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Search of human proteins with 22749459
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749459 glypican 2 [Homo sapiens]
(579 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749459 glypican 2 [Homo sapiens] 1175 0.0
gi|5031719 glypican 6 precursor [Homo sapiens] 451 e-127
gi|21614525 glypican 4 [Homo sapiens] 400 e-111
gi|167001141 glypican 1 precursor [Homo sapiens] 385 e-107
gi|4758464 glypican 5 [Homo sapiens] 147 3e-35
gi|4758462 glypican 3 [Homo sapiens] 125 8e-29
gi|28269693 xylosyltransferase I [Homo sapiens] 38 0.029
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 38 0.029
gi|167466169 growth arrest-specific 1 [Homo sapiens] 37 0.038
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 37 0.065
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 37 0.065
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 36 0.085
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 36 0.085
gi|4758392 forkhead box D1 [Homo sapiens] 36 0.11
gi|109452587 family with sequence similarity 98, member B isofor... 36 0.11
gi|36796743 methylenetetrahydrofolate dehydrogenase (NADP+ depen... 35 0.14
gi|11034843 ras homolog gene family, member U [Homo sapiens] 35 0.14
gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens] 35 0.19
gi|114145479 neuroepithelial cell transforming gene 1 isoform 1 ... 35 0.25
gi|19923327 neuroepithelial cell transforming gene 1 isoform 2 [... 35 0.25
gi|34452681 ring finger protein 10 [Homo sapiens] 35 0.25
gi|239753407 PREDICTED: hypothetical protein [Homo sapiens] 34 0.32
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 34 0.32
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] 34 0.42
gi|148839294 Ca2+-dependent activator protein for secretion 2 is... 34 0.42
gi|148839284 Ca2+-dependent activator protein for secretion 2 is... 34 0.42
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens] 34 0.42
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens] 34 0.42
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens] 34 0.42
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens] 33 0.55
>gi|22749459 glypican 2 [Homo sapiens]
Length = 579
Score = 1175 bits (3040), Expect = 0.0
Identities = 579/579 (100%), Positives = 579/579 (100%)
Query: 1 MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLR 60
MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLR
Sbjct: 1 MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLR 60
Query: 61 VCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQH 120
VCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQH
Sbjct: 61 VCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQH 120
Query: 121 SLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHP 180
SLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHP
Sbjct: 121 SLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHP 180
Query: 181 QYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSE 240
QYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSE
Sbjct: 181 QYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSE 240
Query: 241 ALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGL 300
ALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGL
Sbjct: 241 ALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGL 300
Query: 301 LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAP 360
LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAP
Sbjct: 301 LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAP 360
Query: 361 PPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAA 420
PPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAA
Sbjct: 361 PPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAA 420
Query: 421 DASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATAR 480
DASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATAR
Sbjct: 421 DASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATAR 480
Query: 481 MKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGG 540
MKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGG
Sbjct: 481 MKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGG 540
Query: 541 GGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR 579
GGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR
Sbjct: 541 GGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR 579
>gi|5031719 glypican 6 precursor [Homo sapiens]
Length = 555
Score = 451 bits (1160), Expect = e-127
Identities = 227/512 (44%), Positives = 329/512 (64%), Gaps = 16/512 (3%)
Query: 2 SALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRV 61
+ + PLL LLL L P RSC E RQ GA+G+SL IP I+GEHLR+
Sbjct: 7 AVILPLLGLLLSL-------PAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRI 59
Query: 62 CPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHS 121
CPQEYTCC++E E +L ++++ F LVE++ F+ T +RH+KFDEFF E+L A+ S
Sbjct: 60 CPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKS 119
Query: 122 LTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQ 181
L +F +YG LY Q++ +F LF+ L+ +Y L++ L DFWA+LLER+F L++PQ
Sbjct: 120 LNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQ 179
Query: 182 YSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEA 241
Y F DYL C+S+ L+PFGD PR+L++Q+TR +AAR FVQGL GR V +
Sbjct: 180 YHFSEDYLECVSKYTD----QLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRV 235
Query: 242 LKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGL 300
KV + GC +ALM+++ CP CRG+P++ PC +CLNV++GCL+++ L+ +W ++D +
Sbjct: 236 SKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAM 295
Query: 301 LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPA-RNRRA 359
L++A++L+GPF+ E + I VKISE +M +QENS +VSA+VFQ CG P P PA R+ R+
Sbjct: 296 LLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARS 355
Query: 360 PPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMA 419
P E + EERPTTAAGT+L RLV +++E+L + W+ L T+C D +
Sbjct: 356 AP--ENFNTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVT 413
Query: 420 ADASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATA 479
A S E CW G + RYLP ++ Q+NNPE+ VD + PD R++ + LR T
Sbjct: 414 AGTSNE-EECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTN 472
Query: 480 RMKTAALGHDLDGQDADEDASGSGGGQQYADD 511
++K A G+D++ QD +++SGSG G DD
Sbjct: 473 KLKNAYNGNDVNFQDTSDESSGSGSGSGCMDD 504
>gi|21614525 glypican 4 [Homo sapiens]
Length = 556
Score = 400 bits (1028), Expect = e-111
Identities = 201/478 (42%), Positives = 305/478 (63%), Gaps = 6/478 (1%)
Query: 29 TRSCAETRQVLGARGYSLNLIPPALISGEHLRVCPQEYTCCSSETEQRLIRETEATFRGL 88
++SC+E R++ ++G++ N P I+G+HL++CPQ TCCS E E++ +++ F+ +
Sbjct: 27 SKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSV 86
Query: 89 VEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRL 148
V + + L A+R++KFDEFF E+L A+ SL +F +YG LY Q++ +F LF L
Sbjct: 87 VSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVEL 146
Query: 149 RDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGSLQPFGD 208
+ +Y L++ L DFWA+LLER+F L++ QY F +YL C+S+ L+PFGD
Sbjct: 147 KRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTE----QLKPFGD 202
Query: 209 SPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPLCRGVPS 268
PR+L+LQ+TR VAAR F QGL +VVS+ V + C+ AL+++I C CRG+ +
Sbjct: 203 VPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVT 262
Query: 269 LMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGLLILADKLQGPFSFELTAESIGVKISEG 327
+ PC +C N++RGCL+++G L+ +W N++D +L++A++L+GPF+ E + I VKIS+
Sbjct: 263 VKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDA 322
Query: 328 LMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTTAAGTNL 387
+M +Q+NS +VS +VFQ CGPP P+PA + EERPTTAAGT+L
Sbjct: 323 IMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSL 382
Query: 388 HRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPPVVGGSP 447
RLV +++E+L + + FW+ L VC D RMAA E CW G G+ RYL V G
Sbjct: 383 DRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNE-DDCWNGKGKSRYLFAVTGNGL 441
Query: 448 AEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASGSGGG 505
A Q NNPE++VD S PD+ R+ + LR T++MK A G+D+D D +++SG G G
Sbjct: 442 ANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSG 499
>gi|167001141 glypican 1 precursor [Homo sapiens]
Length = 558
Score = 385 bits (988), Expect = e-107
Identities = 206/506 (40%), Positives = 302/506 (59%), Gaps = 16/506 (3%)
Query: 23 GSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRVCPQEYTCCSSETEQRLIRETE 82
G A +RSC E RQ+ GA+G+SL+ +P A ISGEHLR+CPQ YTCC+SE E+ L +
Sbjct: 23 GDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENLANRSH 82
Query: 83 ATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFN 142
A + DS L LA + R FD+ F +L+ ++ +L F ++G LY Q+A F
Sbjct: 83 AELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFR 142
Query: 143 GLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGS 202
L+S LR +Y + L++TLA+FWA+LLER+F LHPQ P DYL CL + A +
Sbjct: 143 DLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAE----A 198
Query: 203 LQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPL 262
L+PFG++PR LRL+ TR VAAR+FVQGL +VV + +VP+ CS+A+M+L+ C
Sbjct: 199 LRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRAVMKLVYCAH 258
Query: 263 CRGVPSLMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGLLILADKLQGPFSFELTAESIG 321
C GVP PC +C NV++GCL+++ L+ +W N LD ++++ DK G E S+
Sbjct: 259 CLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVH 318
Query: 322 VKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTT 381
++E + LQ+N ++A+V Q CG P N + P P E+ R + ERP +
Sbjct: 319 TWLAEAINALQDNRDTLTAKVIQGCGNPKV----NPQGPGPEEKRRR--GKLAPRERPPS 372
Query: 382 AAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPP 441
L +LV E + +L ++ FW L T+C + + AS + CW G RGRYLP
Sbjct: 373 G---TLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMALSTASDDR--CWNGMARGRYLPE 427
Query: 442 VVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASG 501
V+G A Q+NNPE++VD + PD+ R++ +QL+ T R+++A G+D+D QDA +D SG
Sbjct: 428 VMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYNGNDVDFQDASDDGSG 487
Query: 502 SGGGQQYADDWMAGAVAPPARPPRPP 527
SG G DD + V+ + R P
Sbjct: 488 SGSGDGCLDDLCSRKVSRKSSSSRTP 513
>gi|4758464 glypican 5 [Homo sapiens]
Length = 572
Score = 147 bits (370), Expect = 3e-35
Identities = 114/443 (25%), Positives = 199/443 (44%), Gaps = 26/443 (5%)
Query: 30 RSCAETRQVLGARGY-SLNLIPPALISGEHLRVC-PQEYTCCSSETEQRLIRETEATFRG 87
++C E R++ R ++ +P + +G L+VC ++ TCC+ + E+R +
Sbjct: 28 QTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQ 87
Query: 88 LVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSR 147
++ S S L ++ F E ++ A++ + LF +Y + + A +
Sbjct: 88 FLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAA-------AS 140
Query: 148 LRDFYGESGE---GLDDTLADFWAQLLERVFPLLHPQYSFP--PDYLLCLSRLASSTDGS 202
+++F+ + G G D +F + + +FPL++ P D L S
Sbjct: 141 VQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSECIRMARRD 200
Query: 203 LQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPL 262
+ PFG+ P+R+ Q+ R+L+ +R F+Q L G V++ + S+ CS+AL+++ CP
Sbjct: 201 VSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPH 260
Query: 263 CRGVPSLMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGLLILADKLQGPFSFELTAESIG 321
C+G+ PC G+CLNV+RGCL+ L P W Y+ L L+D + G + +
Sbjct: 261 CQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIGHVLLNFH 320
Query: 322 VKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTT 381
+ +++ ++ N K+ QV + CG P P ++ R + + T T
Sbjct: 321 LLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETL 380
Query: 382 AAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGR-YLP 440
A E L R F+ L+ +C + AAD PCW G + Y
Sbjct: 381 ANRRK------EFINSLRLYRSFYGGLADQLCANELAAAD----GLPCWNGEDIVKSYTQ 430
Query: 441 PVVGGSPAEQVNNPELKVDASGP 463
VVG Q NPE+KV P
Sbjct: 431 RVVGNGIKAQSGNPEVKVKGIDP 453
>gi|4758462 glypican 3 [Homo sapiens]
Length = 580
Score = 125 bits (315), Expect = 8e-29
Identities = 121/517 (23%), Positives = 210/517 (40%), Gaps = 32/517 (6%)
Query: 7 LLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRVC-PQE 65
L++ +L PG +C + R L +P + G L+VC P+
Sbjct: 10 LVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKG 69
Query: 66 YTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQL 125
TCCS + E++ L++ + L + F E F ++ A++ +
Sbjct: 70 PTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAM 129
Query: 126 FSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFP 185
F ++Y L Q A F G F Y G D + D +L + +FP+++ Q P
Sbjct: 130 FKNNYPSLTPQ-AFEFVGEFFTDVSLYIL---GSDINVDDMVNELFDSLFPVIYTQLMNP 185
Query: 186 --PDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALK 243
PD L ++ L+ FG+ P+ + Q++++L R F+Q L G V++
Sbjct: 186 GLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDH 245
Query: 244 VPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSS-RGLEPDWGNYLDGLLI 302
+ S+ C + L R+ C C+G+ + PC G+C V++GC++ ++ W Y+ L
Sbjct: 246 LKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEE 305
Query: 303 LADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPP 362
L + + + E + I + + Y+Q+N+ K++ + + C R+ P
Sbjct: 306 LVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPED 365
Query: 363 REEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADA 422
++ + E T ++ EL ++L F++ L +C S +A +
Sbjct: 366 LFIDKKVLKVAHVEHEETLSSRRR------ELIQKLKSFISFYSALPGYICSHSPVAEND 419
Query: 423 SLEAAPCWTGAGR-GRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRL----QLRAA 477
+L CW G RY Q N ELK+ P V +L QL
Sbjct: 420 TL----CWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRT 475
Query: 478 TARMKTAALGHDLD---------GQDADEDASGSGGG 505
+ K L +LD G D DE GSG G
Sbjct: 476 MSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDG 512
>gi|28269693 xylosyltransferase I [Homo sapiens]
Length = 959
Score = 37.7 bits (86), Expect = 0.029
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 8/62 (12%)
Query: 502 SGGGQQYADDWMAGAVAPPARP-PR------PPYPPR-RDGSGGKGGGGSARYNQGRSRS 553
SG G++ + G PP P PR P P R G GG GGGG R Q R+R
Sbjct: 40 SGAGERRGGAAVGGGEQPPPAPAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARG 99
Query: 554 GG 555
GG
Sbjct: 100 GG 101
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 6/70 (8%)
Query: 492 GQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQG-- 549
GQD +SG G G Y + +G + R GSGG GGGG YN+
Sbjct: 178 GQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSG 237
Query: 550 ----RSRSGG 555
R R GG
Sbjct: 238 GYEPRGRGGG 247
Score = 32.7 bits (73), Expect = 0.94
Identities = 24/79 (30%), Positives = 26/79 (32%), Gaps = 24/79 (30%)
Query: 492 GQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYP---------------PRRDGSG 536
G+ G GGGQQ A DW P P P+ DG G
Sbjct: 406 GRGGFPSGGGGGGGQQRAGDWKC---------PNPTCENMNFSWRNECNQCKAPKPDGPG 456
Query: 537 GKGGGGSARYNQGRSRSGG 555
G GG N G R GG
Sbjct: 457 GGPGGSHMGGNYGDDRRGG 475
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/58 (34%), Positives = 24/58 (41%)
Query: 502 SGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIG 559
S GGQQ + P + Y G GG GGGG+ +Q SGG S G
Sbjct: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
>gi|167466169 growth arrest-specific 1 [Homo sapiens]
Length = 345
Score = 37.4 bits (85), Expect = 0.038
Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 20/88 (22%)
Query: 496 DEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRR-DGSGGKGGGGSARYNQGRSRSG 554
DE +G GG+Q DD P+PPR G+ GG G Y GR SG
Sbjct: 271 DEQRTGGAGGEQPLDD-----------DDGVPHPPRPGSGAAASGGRGDLPYGPGRRSSG 319
Query: 555 G----ASIGFHTQTILILSLSALALLGP 578
G A G T IL L LLGP
Sbjct: 320 GGGRLAPRGAWTPLASIL----LLLLGP 343
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/192 (26%), Positives = 75/192 (39%), Gaps = 21/192 (10%)
Query: 344 QECGPPDPVPARNRRAP--PPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARM 401
+ P P AR+++ P P R GR +++P T+ H + R+ A
Sbjct: 974 RHASPARPPAARSQQHPSVPRRMTPGR-----APQQQPPPPVATSQHHPGPQSRD--AGR 1026
Query: 402 RGFWARLSLTVCGDSRMAADA-SLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDA 460
RLSLT G R + S ++ +T + RG LP + Q + + D
Sbjct: 1027 SPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGM-LPTAL----QNQDEDAQGSYDD 1081
Query: 461 SGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPP 520
+V + R AA A+ A+L E +G+G G + G A P
Sbjct: 1082 DSTEVEAQDVRAPAHAARAKEAAASLPK----HQQVESPTGAGAGGDHRSQ--RGHAASP 1135
Query: 521 ARPPRPPYPPRR 532
ARP RP P R
Sbjct: 1136 ARPSRPGGPQSR 1147
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 36.6 bits (83), Expect = 0.065
Identities = 42/138 (30%), Positives = 50/138 (36%), Gaps = 21/138 (15%)
Query: 435 RGRYLPPVVGGSPAEQVNNP-ELKVDASGPDVPTRRRRLQLRAATARMKT---------A 484
RGR V SPA+ + P P VP AA+A T A
Sbjct: 288 RGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA 347
Query: 485 ALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPA------RPPRPPYPPRRDGSGGK 538
A L + + + SG YA AVAPPA PRPP G GG
Sbjct: 348 APPSALGPKASPAPSHNSGTPAPYAQ-----AVAPPAPSGPSTTQPRPPSVQPSGGGGGG 402
Query: 539 GGGGSARYNQGRSRSGGA 556
GGG + + S GGA
Sbjct: 403 SGGGGSSSSSNSSAGGGA 420
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 36.2 bits (82), Expect = 0.085
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 36/129 (27%)
Query: 482 KTAALGHDLDGQDADEDASGSGGGQQ--YADDWMAGAV-----APPARPPRPPY------ 528
+ AA+ D DG++A S G + + DW G + P R P+ PY
Sbjct: 602 RVAAVDAD-DGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
Query: 529 -----PP----------------RRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILI 567
PP G GG GGGGS + Q SRSGG ILI
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEH-QRPSRSGGGETSLDLTLILI 719
Query: 568 LSLSALALL 576
++L +++ +
Sbjct: 720 IALGSVSFI 728
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 36.2 bits (82), Expect = 0.085
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 36/129 (27%)
Query: 482 KTAALGHDLDGQDADEDASGSGGGQQ--YADDWMAGAV-----APPARPPRPPY------ 528
+ AA+ D DG++A S G + + DW G + P R P+ PY
Sbjct: 602 RVAAVDAD-DGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
Query: 529 -----PP----------------RRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILI 567
PP G GG GGGGS + Q SRSGG ILI
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEH-QRPSRSGGGETSLDLTLILI 719
Query: 568 LSLSALALL 576
++L +++ +
Sbjct: 720 IALGSVSFI 728
>gi|4758392 forkhead box D1 [Homo sapiens]
Length = 465
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 25/115 (21%)
Query: 487 GHDLDGQDADEDASGSGGGQQYA------------------------DDWMAGAVAPPA- 521
G D + ++ ++D G GGG + A +D +APPA
Sbjct: 25 GEDEEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYAGEDELEDLEEEEDDDDILLAPPAG 84
Query: 522 RPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILILSLSALALL 576
P PP P G+G GGGG G S GA ++L +A+L
Sbjct: 85 GSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAIL 139
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 35.8 bits (81), Expect = 0.11
Identities = 15/36 (41%), Positives = 19/36 (52%)
Query: 520 PARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGG 555
P P PP+ R++G GG+GG G GR GG
Sbjct: 317 PPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGG 352
>gi|36796743 methylenetetrahydrofolate dehydrogenase (NADP+
dependent) 1-like [Homo sapiens]
Length = 978
Score = 35.4 bits (80), Expect = 0.14
Identities = 21/44 (47%), Positives = 23/44 (52%), Gaps = 9/44 (20%)
Query: 522 RPPRPPYPPRR------DGSGGKGGGGSAR---YNQGRSRSGGA 556
RPP+PP PPRR SGG GGGG R Q R + G A
Sbjct: 14 RPPQPPGPPRRLRVPCRASSGGGGGGGGGREGLLGQRRPQDGQA 57
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 35.4 bits (80), Expect = 0.14
Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 515 GAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGA 556
G A P R PP PPRR+ GG+GG G GR R+GGA
Sbjct: 6 GDPAFPDRCEAPPVPPRRE-RGGRGGRGPGEPG-GRGRAGGA 45
>gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens]
Length = 865
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/61 (40%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 495 ADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSG 554
A +AS GGQ +D GA A P P PR G GG G GG R+ Q ++RS
Sbjct: 20 APPEASHLLGGQGPEED--GGAGAKPLGPRAQAAAPRERGGGGGGAGGRPRF-QYQARSD 76
Query: 555 G 555
G
Sbjct: 77 G 77
>gi|114145479 neuroepithelial cell transforming gene 1 isoform 1
[Homo sapiens]
Length = 596
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 430 WTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHD 489
W R P GSP E PEL + G R+ Q RA+T T
Sbjct: 492 WFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQV---- 547
Query: 490 LDGQDADEDASGSGGGQQYADD 511
+ DE+A G G Q A+D
Sbjct: 548 ----EVDENAYRCGSGMQMAED 565
>gi|19923327 neuroepithelial cell transforming gene 1 isoform 2
[Homo sapiens]
Length = 542
Score = 34.7 bits (78), Expect = 0.25
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 430 WTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHD 489
W R P GSP E PEL + G R+ Q RA+T T
Sbjct: 438 WFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQV---- 493
Query: 490 LDGQDADEDASGSGGGQQYADD 511
+ DE+A G G Q A+D
Sbjct: 494 ----EVDENAYRCGSGMQMAED 511
>gi|34452681 ring finger protein 10 [Homo sapiens]
Length = 811
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 484 AALGHDLD---GQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGG 540
AA D+D G ++ +SGS GQQ PP P + S GK
Sbjct: 9 AATASDMDKNSGSNSSSASSGSSKGQQ-----------PPRSASAGPAGESKPKSDGKNS 57
Query: 541 GGSARYNQGRSRSGGASIGFHTQT 564
GS RYN+ R S + F+ Q+
Sbjct: 58 SGSKRYNRKRELSYPKNESFNNQS 81
>gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]
Length = 182
Score = 34.3 bits (77), Expect = 0.32
Identities = 28/75 (37%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 474 LRAATARMKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRD 533
+RA A TAA G G A SG GGQ+ + A APP P P
Sbjct: 1 MRAPPATAATAAGGATGGGPQAAR-RSGVQGGQRNS----TSARAPPPPPLAPSSSSSSG 55
Query: 534 GSGGKGGGGSARYNQ 548
SG GGGGS Q
Sbjct: 56 SSGSSGGGGSGSAGQ 70
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 34.3 bits (77), Expect = 0.32
Identities = 27/82 (32%), Positives = 30/82 (36%), Gaps = 16/82 (19%)
Query: 489 DLDGQDADEDASGSGGGQQYADDWMA---GAVAPPARPPRP---------PYPPRRDGSG 536
D DG D D S G Y D + + APP R P P Y RDG G
Sbjct: 262 DRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYG 321
Query: 537 GK----GGGGSARYNQGRSRSG 554
G S Y+ GR R G
Sbjct: 322 GSRDSYSSSRSDLYSSGRDRVG 343
Score = 32.7 bits (73), Expect = 0.94
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 10/80 (12%)
Query: 491 DGQDADEDASGSGGG-------QQYADDWMAGAVAPPARPPRPPYPPR--RDGSGGKGGG 541
D +DA D +G Q + +G PP PPR PPR R G GG GG
Sbjct: 61 DAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGPPP-PPRSRGPPRGLRGGRGGSGGT 119
Query: 542 GSARYNQGRSRSGGASIGFH 561
G GG S+ F+
Sbjct: 120 RGPPSRGGHMDDGGYSMNFN 139
>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 33.9 bits (76), Expect = 0.42
Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 22/126 (17%)
Query: 433 AGRGRYLP-PVVG----GSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALG 487
AG GR+ P P VG G ++ V SG +RR LR R + A LG
Sbjct: 111 AGGGRHSPRPAVGTIFRGGRKGRLREGRGAVRGSG-----KRRGWGLRPQRVRSRLAGLG 165
Query: 488 HDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGG-KGGGGSARY 546
G A G G + +P P + R G GG +GGGG AR
Sbjct: 166 APRGGAAAPRGWGGQGAERLGVH-----------QPGLPTHAALRGGGGGSEGGGGGARP 214
Query: 547 NQGRSR 552
+ R+R
Sbjct: 215 SPPRAR 220
>gi|148839294 Ca2+-dependent activator protein for secretion 2
isoform a [Homo sapiens]
Length = 1296
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 490 LDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSAR 545
LD ++E++ G ++ + D + A + PP P RRD G GGGG+AR
Sbjct: 2 LDPSSSEEESDE--GLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAAR 55
>gi|148839284 Ca2+-dependent activator protein for secretion 2
isoform b [Homo sapiens]
Length = 1255
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 490 LDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSAR 545
LD ++E++ G ++ + D + A + PP P RRD G GGGG+AR
Sbjct: 2 LDPSSSEEESDE--GLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAAR 55
>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
Length = 571
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 518 APPARPPRPPYP----PRRDGSGGKGGGGSARYNQGRSRSGG 555
A PA P PP P PRR G G GGGG+ R R G
Sbjct: 14 ADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGGGDRDRDSG 55
>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 518 APPARPPRPPYP----PRRDGSGGKGGGGSARYNQGRSRSGG 555
A PA P PP P PRR G G GGGG+ R R G
Sbjct: 14 ADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGGGDRDRDSG 55
>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 518 APPARPPRPPYP----PRRDGSGGKGGGGSARYNQGRSRSGG 555
A PA P PP P PRR G G GGGG+ R R G
Sbjct: 14 ADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGGGDRDRDSG 55
>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/39 (46%), Positives = 19/39 (48%), Gaps = 5/39 (12%)
Query: 522 RPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIGF 560
RPP PPR G GG+GGG G R GG GF
Sbjct: 160 RPPGEKGPPRGGGRGGRGGGRG-----GGGRGGGRGGGF 193
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,225,400
Number of Sequences: 37866
Number of extensions: 1407169
Number of successful extensions: 11914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 11106
Number of HSP's gapped (non-prelim): 776
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.