Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 17864090
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
(1259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 2630 0.0
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 2567 0.0
gi|217416343 fibrosin-like 1 [Homo sapiens] 619 e-177
gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo s... 441 e-123
gi|157364934 fibrosin [Homo sapiens] 261 2e-69
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 86 3e-16
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 86 3e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 86 3e-16
gi|55750053 atrophin-1 [Homo sapiens] 84 6e-16
gi|55750041 atrophin-1 [Homo sapiens] 84 6e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 81 5e-15
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 77 8e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 77 1e-13
gi|150417989 cyclin K isoform 1 [Homo sapiens] 73 1e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 71 7e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 8e-11
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 65 3e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 65 3e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 5e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 64 9e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 1e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 64 1e-09
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 64 1e-09
gi|54860079 nadrin isoform 1 [Homo sapiens] 63 2e-09
gi|153792074 proline rich 12 [Homo sapiens] 63 2e-09
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 63 2e-09
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 63 2e-09
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 63 2e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 5e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 61 8e-09
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 2630 bits (6816), Expect = 0.0
Identities = 1259/1259 (100%), Positives = 1259/1259 (100%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
Query: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP
Sbjct: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP
Sbjct: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
Query: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA
Sbjct: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
Query: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ
Sbjct: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
Query: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF
Sbjct: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
Query: 601 GSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQI 660
GSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQI
Sbjct: 601 GSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQI 660
Query: 661 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 720
YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP
Sbjct: 661 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 720
Query: 721 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 780
TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG
Sbjct: 721 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 780
Query: 781 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 840
PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD
Sbjct: 781 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 840
Query: 841 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900
DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES
Sbjct: 841 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900
Query: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960
RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR
Sbjct: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960
Query: 961 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 1020
EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA
Sbjct: 961 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 1020
Query: 1021 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1080
SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR
Sbjct: 1021 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1080
Query: 1081 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1140
ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR
Sbjct: 1081 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1140
Query: 1141 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1200
REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT
Sbjct: 1141 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1200
Query: 1201 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1259
AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
Sbjct: 1201 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1259
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 2567 bits (6654), Expect = 0.0
Identities = 1235/1259 (98%), Positives = 1235/1259 (98%), Gaps = 24/1259 (1%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
Query: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP
Sbjct: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP
Sbjct: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
Query: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA
Sbjct: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
Query: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ
Sbjct: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
Query: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF
Sbjct: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
Query: 601 GSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQI 660
GSLQGAFQPK LTDPFRPMLRKPGKWCAMHVHIAWQI
Sbjct: 601 GSLQGAFQPK------------------------LTDPFRPMLRKPGKWCAMHVHIAWQI 636
Query: 661 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 720
YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP
Sbjct: 637 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 696
Query: 721 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 780
TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG
Sbjct: 697 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 756
Query: 781 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 840
PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD
Sbjct: 757 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 816
Query: 841 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900
DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES
Sbjct: 817 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 876
Query: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960
RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR
Sbjct: 877 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 936
Query: 961 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 1020
EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA
Sbjct: 937 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 996
Query: 1021 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1080
SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR
Sbjct: 997 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1056
Query: 1081 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1140
ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR
Sbjct: 1057 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1116
Query: 1141 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1200
REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT
Sbjct: 1117 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1176
Query: 1201 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1259
AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
Sbjct: 1177 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1235
>gi|217416343 fibrosin-like 1 [Homo sapiens]
Length = 1045
Score = 619 bits (1596), Expect = e-177
Identities = 481/1300 (37%), Positives = 594/1300 (45%), Gaps = 309/1300 (23%)
Query: 10 LRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---SSA 66
+R RRSR+QRDR RR A A ++G G PP + A
Sbjct: 5 VRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGL----RGAPPRGAAPA 60
Query: 67 PSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKR 126
P RPPRR+RRES+S EE++IDGFA+ SF T EALEKD+ALKP ER EK + L KK R
Sbjct: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
Query: 127 EALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSD 186
E+ T + S+ R P S ++ C K P ++ + RDSD
Sbjct: 121 ESETCPPAEPSENRR---PLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSD 177
Query: 187 SESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
+S +SSR+ LSDSSA + G GY CDS+S ++KAS SEKLF
Sbjct: 178 DDSV------LEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKAS-VGSEKLFA----- 225
Query: 247 KDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPI 306
P G E AGP VPK+SGLERS+E S + P P PCP
Sbjct: 226 --PGTDKGPALEKSEAKAGP-VPKVSGLERSRELSAESFL-PTASPAPHAAPCPG----- 276
Query: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
PPP S P E PAP +PP PQ
Sbjct: 277 ---------------------------PPPGSRANPLVKKEP---PAPHRHTPQPPPPQ- 305
Query: 367 PTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
P LL ++P SL +++ L+ LS S S AP + H
Sbjct: 306 PRGLLPTHVPA--------SLGAFAGHSQAAANGLHGLSRSSS--------APLGLGKHV 349
Query: 427 SASPF---PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
S SP P +H L S H H MFA P LPPPP L + SL + GHP
Sbjct: 350 SLSPHGPGPHLSTSHLALRS------QAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHP 403
Query: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQH-- 541
A + ++LRQELNTRFL + GASLGP LR EFHQHQH HQHTHQHTHQH
Sbjct: 404 A-----DHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQH 458
Query: 542 TFTPFPHAIPPTAIMPTPAPPMFDKYPTKVD-PFYRHS---LFHSYPPAVSGIPPMIPPT 597
TF PFP +PPT P APP FDKY K+D P++RHS F S+PPA+ G+P ++P
Sbjct: 459 TFAPFPAGLPPT---PPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP 515
Query: 598 GPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRP---------------- 641
GPFGSLQGAFQPK S+P + T Q L P RP
Sbjct: 516 GPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQ-GRTLVPPGRPRGARDSRSLQKTWVGV 574
Query: 642 ---------MLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPG 692
+ +KPG+WCA+HV IAWQIY HQQK+K +MQ DPHKL+ G K + RPP
Sbjct: 575 APAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK-EMQLDPHKLEVGAKLDLFGRPPA 633
Query: 693 PSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTG 752
P +F H+P DLARP LF + GAAHP PFGP H +FL +PF+RPSTF G
Sbjct: 634 PGVFAGFHYPQDLARP--LFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGG 691
Query: 753 LAAVGGNAFGGLGNPSVTPN-SMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLK 811
L ++ +AFGGLG+ ++ P S+F K+G SV +PHE WNRLHR PPSFP PPPW K
Sbjct: 692 LGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPK 751
Query: 812 PGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK-RHSSHPSPAPVLPVNALGHTR 870
+ ER ++ HDR+ D K+++ER+ +EK R S SPA GH
Sbjct: 752 SVDAERVSALTNHDREPD-------NGKEEQERDLLEKTRLLSRASPA-----TPAGHPV 799
Query: 871 SSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 930
S + +E P ERE E + KE P K+
Sbjct: 800 SG---LLLRAQSELGRSGAPAEREA------------EPRVKESRSPAKE---------- 834
Query: 931 EEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDH 990
E AK AR P+ A P +VKVKEER ED
Sbjct: 835 EAAKMPARASPPH------SKAAP-----------------------GDVKVKEERGED- 864
Query: 991 DLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFM 1050
ASEPP + +HP PL +
Sbjct: 865 ----------EASEPP----AGGLHPAPLQ-----------------------------L 881
Query: 1051 GISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLY 1110
G+ G ER P F W+P R L P R P S L
Sbjct: 882 GL----GRERLGAPGFAWEPFRG-LELPRRAFPAAAPAP--------------GSAALLE 922
Query: 1111 EADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSV 1170
+R +RDREPH YS P R LR + E R +
Sbjct: 923 PPERPYRDREPHGYS-------------PER----------------LRGELERARAPHL 953
Query: 1171 HPA--SLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPP-TAALSAPPPLISTL 1227
PA +LDG L P L ++H+PR+SP A NGLL +TPP AAL APPPL+ T
Sbjct: 954 PPAAPALDGAL------LPSLGALHFPRLSP-AALHNGLLARTPPAAAALGAPPPLV-TA 1005
Query: 1228 GGRPVSP----RRTTPLS----AEIRERPPSHTLKDIEAR 1259
G P P RTTPL E R+ PS ++EAR
Sbjct: 1006 AGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR 1045
>gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo
sapiens]
Length = 266
Score = 441 bits (1134), Expect = e-123
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF 220
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF 220
>gi|157364934 fibrosin [Homo sapiens]
Length = 460
Score = 261 bits (668), Expect = 2e-69
Identities = 132/298 (44%), Positives = 193/298 (64%), Gaps = 17/298 (5%)
Query: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPG 622
MF+KYP K++ +RH+ + ++PPAV G+PP +PP FGSLQGAFQPK++NP ++ R G
Sbjct: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNP-ELPPRLG 59
Query: 623 TVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL 682
VP L QK ++ D FRP LRKPGKWCAMHV +A+ I HQ+K M+ D HKLDF
Sbjct: 60 PVPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEK----MKGDSHKLDF-- 113
Query: 683 KPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPF-GPPPHHSNFLNPAAHL 741
+ + L PGP +GA+ +L+ P++LF+A GA H PF P H FL+P+ H+
Sbjct: 114 RNDLLPCLPGP--YGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHI 171
Query: 742 EPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSV-QNFSNPHEPWNRLHRTP 800
+PF RP++F LAA+ AFGGLG+P+ ++F K+ P F++P +PW RLHR+P
Sbjct: 172 DPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSP 231
Query: 801 PSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPA 858
+FP W++P E R+ + D++R V++R+ S++K++K+R+ R SPA
Sbjct: 232 LTFPA---WVRPPEAARTPGS---DKERPVERREPSITKEEKDRDLPFSRPQLRVSPA 283
Score = 36.2 bits (82), Expect = 0.20
Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 1166 RLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIS 1225
RL+ + PA HP L + P P A LL+KTPP A L APPPL+
Sbjct: 394 RLYGLEPA-------HPLLYSRLAP----PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP 442
Query: 1226 TLGGRPVSPRR 1236
RP SP R
Sbjct: 443 --APRPSSPPR 451
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 85.5 bits (210), Expect = 3e-16
Identities = 125/511 (24%), Positives = 172/511 (33%), Gaps = 134/511 (26%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 76 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 134
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 135 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 171
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 172 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 228
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQ-LLHQNLPPV---QAHPSAQSLS 388
Q P P P +Q AP QRPP P P H L P+ PSA S +
Sbjct: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288
Query: 389 QP----LSAYNSSSLSLNSL--------------SSSRSSTPAKTQPAP--PHISHHPSA 428
QP SL L +S+ P T PA PH S A
Sbjct: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA 348
Query: 429 S----------------PFPLSLPNHSPLHSFTPTLQ---PPAHSHHPNMFAPP-----T 464
S P PL++P+ P + TP Q P AH H P++ P
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMNA 407
Query: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF 524
LPPPP L S HP + ++ QS +S PP L
Sbjct: 408 NLPPPPALKPLSSLSTHHPPSAHPPPLQLM----------PQSQPLPSSPAQPPGL---- 453
Query: 525 HQHQHQHQHTHQHTHQHTFTPFPHAIPPTAI-MPTPAPPMFDKYPTKVDPFYRHSLFHSY 583
T P P + PPT + P PP F +
Sbjct: 454 -------------TQSQNLPPPPASHPPTGLHQVAPQPP-----------------FAQH 483
Query: 584 PPAVSGIPPMIPPTGPFGSLQGAFQPKTSNP 614
P G PP+ PPT P S A ++ P
Sbjct: 484 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514
Score = 52.4 bits (124), Expect = 3e-06
Identities = 82/319 (25%), Positives = 107/319 (33%), Gaps = 60/319 (18%)
Query: 311 TEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQ-GPPEAQLQPAPQPQVQRPPRPQSPTQ 369
++PQL P R P P ++ PP GP L+ + P SPT
Sbjct: 664 SDPQLSGPGH-----MRPSFEPPPTTIAAVPPYIGPDTPALRTLSE---YARPHVMSPTN 715
Query: 370 LLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSAS 429
H P+ + PL AY+ L N + R + + I
Sbjct: 716 RNHPFYMPLNP-------TDPLLAYHMPGL-YNVDPTIRERELREREIREREIRERELRE 767
Query: 430 P----FPLSLPNHSPLHSFTPTLQPPAH-SHHPNMFAPPTALPPP--------PPLTSGS 476
F + P PLH P P H + H + PPTA P P PL
Sbjct: 768 RMKPGFEVKPPELDPLH---PAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERER 824
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF-----HQHQHQH 531
L +AG S D L E A+R ASL P R + H HQH H
Sbjct: 825 LALAGPQLRPEMSYPDRLAAE-------RIHAERMASLTSDPLARLQMFNVTPHHHQHSH 877
Query: 532 QHTHQHTHQH------TFTPFPHAIPPTAIMP----TPAPPMFDKYPTKVDPFYRHSLFH 581
H+H H HQ + P + P P P PP P P + H +
Sbjct: 878 IHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLR 937
Query: 582 SYP----PAVSGIPPMIPP 596
+P P +P IPP
Sbjct: 938 -HPVFGTPYPRDLPGAIPP 955
Score = 49.3 bits (116), Expect = 2e-05
Identities = 65/238 (27%), Positives = 87/238 (36%), Gaps = 23/238 (9%)
Query: 253 VGTLPEHDSQDAGPIVPKISGLERSQE--KSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQ 310
+GT P +P +SQ+ + Q P+ P + P + Q +P PQ
Sbjct: 331 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQ-LPAPQ 389
Query: 311 TE---PQLRAPSPDPDLVQRTEAPPQPPPLST----QPPQG-PPEAQLQPAPQPQVQRPP 362
P L PSP + PP PLS+ PP PP QL P QP P
Sbjct: 390 AHKHPPHLSGPSPF-SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
Query: 363 RPQSPTQLLHQNLPPVQA-HPSA---QSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
+P TQ QNLPP A HP Q QP A + + + T PA
Sbjct: 449 QPPGLTQ--SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 506
Query: 419 PPHISHHP-----SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P S P +AS ++ + PL + + + P PP P P P
Sbjct: 507 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 564
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 85.5 bits (210), Expect = 3e-16
Identities = 125/511 (24%), Positives = 172/511 (33%), Gaps = 134/511 (26%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 688
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 689 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 725
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 782
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQ-LLHQNLPPV---QAHPSAQSLS 388
Q P P P +Q AP QRPP P P H L P+ PSA S +
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 389 QP----LSAYNSSSLSLNSL--------------SSSRSSTPAKTQPAP--PHISHHPSA 428
QP SL L +S+ P T PA PH S A
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA 902
Query: 429 S----------------PFPLSLPNHSPLHSFTPTLQ---PPAHSHHPNMFAPP-----T 464
S P PL++P+ P + TP Q P AH H P++ P
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF 524
LPPPP L S HP + ++ QS +S PP L
Sbjct: 962 NLPPPPALKPLSSLSTHHPPSAHPPPLQLM----------PQSQPLPSSPAQPPGL---- 1007
Query: 525 HQHQHQHQHTHQHTHQHTFTPFPHAIPPTAI-MPTPAPPMFDKYPTKVDPFYRHSLFHSY 583
T P P + PPT + P PP F +
Sbjct: 1008 -------------TQSQNLPPPPASHPPTGLHQVAPQPP-----------------FAQH 1037
Query: 584 PPAVSGIPPMIPPTGPFGSLQGAFQPKTSNP 614
P G PP+ PPT P S A ++ P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Score = 52.4 bits (124), Expect = 3e-06
Identities = 82/319 (25%), Positives = 107/319 (33%), Gaps = 60/319 (18%)
Query: 311 TEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQ-GPPEAQLQPAPQPQVQRPPRPQSPTQ 369
++PQL P R P P ++ PP GP L+ + P SPT
Sbjct: 1218 SDPQLSGPGH-----MRPSFEPPPTTIAAVPPYIGPDTPALRTLSE---YARPHVMSPTN 1269
Query: 370 LLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSAS 429
H P+ + PL AY+ L N + R + + I
Sbjct: 1270 RNHPFYMPLNP-------TDPLLAYHMPGL-YNVDPTIRERELREREIREREIRERELRE 1321
Query: 430 P----FPLSLPNHSPLHSFTPTLQPPAH-SHHPNMFAPPTALPPP--------PPLTSGS 476
F + P PLH P P H + H + PPTA P P PL
Sbjct: 1322 RMKPGFEVKPPELDPLH---PAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERER 1378
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF-----HQHQHQH 531
L +AG S D L E A+R ASL P R + H HQH H
Sbjct: 1379 LALAGPQLRPEMSYPDRLAAE-------RIHAERMASLTSDPLARLQMFNVTPHHHQHSH 1431
Query: 532 QHTHQHTHQH------TFTPFPHAIPPTAIMP----TPAPPMFDKYPTKVDPFYRHSLFH 581
H+H H HQ + P + P P P PP P P + H +
Sbjct: 1432 IHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLR 1491
Query: 582 SYP----PAVSGIPPMIPP 596
+P P +P IPP
Sbjct: 1492 -HPVFGTPYPRDLPGAIPP 1509
Score = 49.3 bits (116), Expect = 2e-05
Identities = 65/238 (27%), Positives = 87/238 (36%), Gaps = 23/238 (9%)
Query: 253 VGTLPEHDSQDAGPIVPKISGLERSQE--KSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQ 310
+GT P +P +SQ+ + Q P+ P + P + Q +P PQ
Sbjct: 885 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQ-LPAPQ 943
Query: 311 TE---PQLRAPSPDPDLVQRTEAPPQPPPLST----QPPQG-PPEAQLQPAPQPQVQRPP 362
P L PSP + PP PLS+ PP PP QL P QP P
Sbjct: 944 AHKHPPHLSGPSPF-SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 363 RPQSPTQLLHQNLPPVQA-HPSA---QSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
+P TQ QNLPP A HP Q QP A + + + T PA
Sbjct: 1003 QPPGLTQ--SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060
Query: 419 PPHISHHP-----SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P S P +AS ++ + PL + + + P PP P P P
Sbjct: 1061 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 85.5 bits (210), Expect = 3e-16
Identities = 125/511 (24%), Positives = 172/511 (33%), Gaps = 134/511 (26%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 688
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 689 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 725
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 782
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQ-LLHQNLPPV---QAHPSAQSLS 388
Q P P P +Q AP QRPP P P H L P+ PSA S +
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 389 QP----LSAYNSSSLSLNSL--------------SSSRSSTPAKTQPAP--PHISHHPSA 428
QP SL L +S+ P T PA PH S A
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA 902
Query: 429 S----------------PFPLSLPNHSPLHSFTPTLQ---PPAHSHHPNMFAPP-----T 464
S P PL++P+ P + TP Q P AH H P++ P
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF 524
LPPPP L S HP + ++ QS +S PP L
Sbjct: 962 NLPPPPALKPLSSLSTHHPPSAHPPPLQLM----------PQSQPLPSSPAQPPGL---- 1007
Query: 525 HQHQHQHQHTHQHTHQHTFTPFPHAIPPTAI-MPTPAPPMFDKYPTKVDPFYRHSLFHSY 583
T P P + PPT + P PP F +
Sbjct: 1008 -------------TQSQNLPPPPASHPPTGLHQVAPQPP-----------------FAQH 1037
Query: 584 PPAVSGIPPMIPPTGPFGSLQGAFQPKTSNP 614
P G PP+ PPT P S A ++ P
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068
Score = 52.4 bits (124), Expect = 3e-06
Identities = 82/319 (25%), Positives = 107/319 (33%), Gaps = 60/319 (18%)
Query: 311 TEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQ-GPPEAQLQPAPQPQVQRPPRPQSPTQ 369
++PQL P R P P ++ PP GP L+ + P SPT
Sbjct: 1218 SDPQLSGPGH-----MRPSFEPPPTTIAAVPPYIGPDTPALRTLSE---YARPHVMSPTN 1269
Query: 370 LLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSAS 429
H P+ + PL AY+ L N + R + + I
Sbjct: 1270 RNHPFYMPLNP-------TDPLLAYHMPGL-YNVDPTIRERELREREIREREIRERELRE 1321
Query: 430 P----FPLSLPNHSPLHSFTPTLQPPAH-SHHPNMFAPPTALPPP--------PPLTSGS 476
F + P PLH P P H + H + PPTA P P PL
Sbjct: 1322 RMKPGFEVKPPELDPLH---PAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERER 1378
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF-----HQHQHQH 531
L +AG S D L E A+R ASL P R + H HQH H
Sbjct: 1379 LALAGPQLRPEMSYPDRLAAE-------RIHAERMASLTSDPLARLQMFNVTPHHHQHSH 1431
Query: 532 QHTHQHTHQH------TFTPFPHAIPPTAIMP----TPAPPMFDKYPTKVDPFYRHSLFH 581
H+H H HQ + P + P P P PP P P + H +
Sbjct: 1432 IHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLR 1491
Query: 582 SYP----PAVSGIPPMIPP 596
+P P +P IPP
Sbjct: 1492 -HPVFGTPYPRDLPGAIPP 1509
Score = 49.3 bits (116), Expect = 2e-05
Identities = 65/238 (27%), Positives = 87/238 (36%), Gaps = 23/238 (9%)
Query: 253 VGTLPEHDSQDAGPIVPKISGLERSQE--KSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQ 310
+GT P +P +SQ+ + Q P+ P + P + Q +P PQ
Sbjct: 885 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQ-LPAPQ 943
Query: 311 TE---PQLRAPSPDPDLVQRTEAPPQPPPLST----QPPQG-PPEAQLQPAPQPQVQRPP 362
P L PSP + PP PLS+ PP PP QL P QP P
Sbjct: 944 AHKHPPHLSGPSPF-SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 363 RPQSPTQLLHQNLPPVQA-HPSA---QSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
+P TQ QNLPP A HP Q QP A + + + T PA
Sbjct: 1003 QPPGLTQ--SQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060
Query: 419 PPHISHHP-----SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P S P +AS ++ + PL + + + P PP P P P
Sbjct: 1061 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 84.3 bits (207), Expect = 6e-16
Identities = 230/986 (23%), Positives = 315/986 (31%), Gaps = 257/986 (26%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG---PPEAQ------L 350
P P P P L P P L A PP L QP G P A L
Sbjct: 286 PSAPPPANFPHVTPNL---PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGL 342
Query: 351 QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P P+ P P S LPP + A + P S+ +SSS + +S SSS SS
Sbjct: 343 PPGPEKGPTLAPSPHS--------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL------QPPAHSHH--PNMFAP 462
SASPFP S S HSF P QPP ++ P+
Sbjct: 395 ----------------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 463 PTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRT 522
PPPPP HP S GA P + T
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPST--------------------GAQSTAHPPVST 478
Query: 523 EFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHS 582
H HQ Q Q Q Q H PP +P P S H+
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHG--------NSGPPPPGAFP---HPLEGGSSHHA 527
Query: 583 YPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPM 642
+P A+S P + P+ P S A P P + T
Sbjct: 528 HPYAMS---PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ---- 580
Query: 643 LRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHP 702
G + H + Q P+ PP P++ +
Sbjct: 581 ----GSYPCSH-----------PSPSQGPQGAPYPF-----------PPVPTVTTS---S 611
Query: 703 HDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH-------LEPFNRPS------- 748
L+ +++ A + T +P GPPP+ +P A+ +P + PS
Sbjct: 612 ATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
Query: 749 TFTGLAAVGGNAFGGLGNPSVTPNSM---------------FGHKDGPSVQNFSNPHEPW 793
+ G + G G+P+V P + GP + EP
Sbjct: 672 GYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731
Query: 794 NRLHRTPPS------FPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV 847
+ TP S P+PPP K ++ AS +A ++ +D+ +S ++ D +
Sbjct: 732 EE-YETPESPVPPARSPSPPP--KVVDVPSHASQSAR-FNKHLDRGFNSCARSDLYFVPL 787
Query: 848 EKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAAD 907
E + V V R+ E+ R RE+++ KERER E ++L
Sbjct: 788 EGSKLAKKRADLVEKVRREAEQRAREEKER------EREREREKERER---EKERELERS 838
Query: 908 EHKAKEGHLP-EKDGHGH-EGRAAGEEAKQLARVP------SPYVRTPVVESARPNSTSS 959
A+EG P E G R E +A VP +P +RT + E ARP+ S
Sbjct: 839 VKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRT-LSEYARPHVMSP 897
Query: 960 RE-----------AEP---RKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRAS 1003
+P PA + ++ + +E R+ D L P
Sbjct: 898 GNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSEL 957
Query: 1004 EP----PPPNSSSSVHPGPLASMPMTVGVTGIHPM---NSISSLDRTRMMTPFMGISPLP 1056
EP P P G LA P G G+HP S+ L+R R+ L
Sbjct: 958 EPLHGVPGPGLDPFPRHGGLALQP---GPPGLHPFPFHPSLGPLERERL--------ALA 1006
Query: 1057 GGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSF 1116
G P+ D Y E R R L NDPL RL +
Sbjct: 1007 AG-----PALRPDM-------SYAERLAAERQHAERVAALGNDPLARLQMLNV------- 1047
Query: 1117 RDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLD 1176
PH + H H H H LH+ ++D H SVHP
Sbjct: 1048 ---TPHHHQHSHIHSH----------------------LHLHQQDAIHAASASVHP---- 1078
Query: 1177 GHLPHPSLITPGLPSMHYPRISPTAG 1202
LI P H RI AG
Sbjct: 1079 -------LIDPLASGSHLTRIPYPAG 1097
Score = 80.1 bits (196), Expect = 1e-14
Identities = 223/1059 (21%), Positives = 350/1059 (33%), Gaps = 195/1059 (18%)
Query: 152 RENDRNLCQHLGKRKKMPKALRQLKP-GQNSCRDSDSESASGESKGFHRSSSRERLSDSS 210
R+N ++ G++K+ P +L+ G+ S + S+ G+++ +++ + R+ ++S
Sbjct: 4 RQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAS 63
Query: 211 APSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLP------------- 257
P G + S+ E + ++A + + + +L
Sbjct: 64 TPKVNKQGR-SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPR 122
Query: 258 --EHDSQDAGPIVPKISGLERSQEKSQDCCKEPI--FEPVVLKDPCPQVAQPIP-QPQTE 312
+ D++ P + +E + S + P + P L P PQ P QP+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLST--QPPQG--PPEAQLQPAPQPQVQRPPRPQSPT 368
+ P P + P PP S Q P G PP QL P V P P P
Sbjct: 183 FE-----PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGP- 235
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSA--YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
+ +A S+ P + + ++ SS S P P P +
Sbjct: 236 ----------KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL 285
Query: 427 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGS 486
++P P + P+ TP L PP P + A PP L G+ + GH
Sbjct: 286 PSAPPPANFPH------VTPNLPPP-----PALRPLNNASASPPGL--GAQPLPGH---- 328
Query: 487 TYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPF 546
L S A G PP T P
Sbjct: 329 ----------------LPSPHAMGQGMGGLPP-----------------GPEKGPTLAPS 355
Query: 547 PHAIPPTAIMPTPAPPMFDKY-----------------PTKVDPFYRHSLFHSYPPAVSG 589
PH++PP A PAPPM Y + PF SYP +
Sbjct: 356 PHSLPP-ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP- 413
Query: 590 IPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVP----HTLLQKDPRLTDPFRPMLRK 645
PPT S Q + S P G P LL PF P
Sbjct: 414 -----PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP---S 465
Query: 646 PGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLF------GAI 699
G H ++ +HHQQ+ ++Q Q + + S PP P F G+
Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ-QQQHHGNSGPPPPGAFPHPLEGGSS 524
Query: 700 HHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHS-NFLNPAAHLEPFNRPSTFTGLAAVG- 757
HH H A +L S +P G PPPH ++ + P + S + + G
Sbjct: 525 HHAHPYAMSPSLGSL--RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 758 -------------GNAFGGLGNPSVTPNS------MFGHKDGPSVQNFSNP--HEPWNRL 796
G + P+VT +S + P+ ++P P+ +
Sbjct: 583 YPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 797 HRTPPSFPT-PPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHP 855
+P ++ T PP KPG + K + P
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
Query: 856 SPAPVLP----VNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKA 911
S P LP A G S+T QI+ E + P R S K + H +
Sbjct: 703 SGLPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Query: 912 KEGHLPEKDGHGHEGRAAGE------EAKQLARVPSPY---VRTPVVESARPNSTSSREA 962
+ + G A + E +LA+ + VR + AR RE
Sbjct: 762 QSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER 821
Query: 963 EPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASM 1022
E K + + VK+ +E + + P P HR PP S+V A++
Sbjct: 822 EREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHR----PPFEPGSAV-----ATV 872
Query: 1023 PMTVGVTGIHPMNSISSLDRTRMMTPFMGISPL--------PGGERFPYPS-FHWDPIRD 1073
P +G + ++S R +M+P P PG + P+ + DP
Sbjct: 873 PPYLG-PDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAR 931
Query: 1074 PLRDPYRELDIHRRDPLGRDFLLRN---DPLHRLSTPRL 1109
RE D+ RD L F ++ +PLH + P L
Sbjct: 932 EREREARERDL--RDRLKPGFEVKPSELEPLHGVPGPGL 968
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/296 (27%), Positives = 102/296 (34%), Gaps = 56/296 (18%)
Query: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQ 379
L Q AP + P L P + P E A P P P T H P +
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 380 AHPSAQSLSQPLSAYNSSSLSLN--SLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN 437
HP PL A + L N +L SS + + + A F +
Sbjct: 901 NHP----FYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Query: 438 HSPLHSFT-PTLQP-PAHSHHPNMFAPPTALPPP-----PPLTSGSLQVAGHPAGSTYSE 490
PLH P L P P H PP P P PL L +A PA
Sbjct: 957 LEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPA------ 1010
Query: 491 QDILRQELN--TRFLAS-QSADRGASLGPPPYLRTEF-----HQHQHQHQHTHQHTHQ-- 540
LR +++ R A Q A+R A+LG P R + H HQH H H+H H HQ
Sbjct: 1011 ---LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQD 1067
Query: 541 --HTFTPFPH-------------AIP-PTAIMPTPAPPMFDKYPTKVDPFYRHSLF 580
H + H IP P +P P P +P + RH LF
Sbjct: 1068 AIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLP----HPLHENEVLRHQLF 1119
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 84.3 bits (207), Expect = 6e-16
Identities = 230/986 (23%), Positives = 315/986 (31%), Gaps = 257/986 (26%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG---PPEAQ------L 350
P P P P L P P L A PP L QP G P A L
Sbjct: 286 PSAPPPANFPHVTPNL---PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGL 342
Query: 351 QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P P+ P P S LPP + A + P S+ +SSS + +S SSS SS
Sbjct: 343 PPGPEKGPTLAPSPHS--------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL------QPPAHSHH--PNMFAP 462
SASPFP S S HSF P QPP ++ P+
Sbjct: 395 ----------------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 463 PTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRT 522
PPPPP HP S GA P + T
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPST--------------------GAQSTAHPPVST 478
Query: 523 EFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHS 582
H HQ Q Q Q Q H PP +P P S H+
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHG--------NSGPPPPGAFP---HPLEGGSSHHA 527
Query: 583 YPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPM 642
+P A+S P + P+ P S A P P + T
Sbjct: 528 HPYAMS---PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ---- 580
Query: 643 LRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHP 702
G + H + Q P+ PP P++ +
Sbjct: 581 ----GSYPCSH-----------PSPSQGPQGAPYPF-----------PPVPTVTTS---S 611
Query: 703 HDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH-------LEPFNRPS------- 748
L+ +++ A + T +P GPPP+ +P A+ +P + PS
Sbjct: 612 ATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
Query: 749 TFTGLAAVGGNAFGGLGNPSVTPNSM---------------FGHKDGPSVQNFSNPHEPW 793
+ G + G G+P+V P + GP + EP
Sbjct: 672 GYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731
Query: 794 NRLHRTPPS------FPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV 847
+ TP S P+PPP K ++ AS +A ++ +D+ +S ++ D +
Sbjct: 732 EE-YETPESPVPPARSPSPPP--KVVDVPSHASQSAR-FNKHLDRGFNSCARSDLYFVPL 787
Query: 848 EKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAAD 907
E + V V R+ E+ R RE+++ KERER E ++L
Sbjct: 788 EGSKLAKKRADLVEKVRREAEQRAREEKER------EREREREKERER---EKERELERS 838
Query: 908 EHKAKEGHLP-EKDGHGH-EGRAAGEEAKQLARVP------SPYVRTPVVESARPNSTSS 959
A+EG P E G R E +A VP +P +RT + E ARP+ S
Sbjct: 839 VKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRT-LSEYARPHVMSP 897
Query: 960 RE-----------AEP---RKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRAS 1003
+P PA + ++ + +E R+ D L P
Sbjct: 898 GNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSEL 957
Query: 1004 EP----PPPNSSSSVHPGPLASMPMTVGVTGIHPM---NSISSLDRTRMMTPFMGISPLP 1056
EP P P G LA P G G+HP S+ L+R R+ L
Sbjct: 958 EPLHGVPGPGLDPFPRHGGLALQP---GPPGLHPFPFHPSLGPLERERL--------ALA 1006
Query: 1057 GGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSF 1116
G P+ D Y E R R L NDPL RL +
Sbjct: 1007 AG-----PALRPDM-------SYAERLAAERQHAERVAALGNDPLARLQMLNV------- 1047
Query: 1117 RDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLD 1176
PH + H H H H LH+ ++D H SVHP
Sbjct: 1048 ---TPHHHQHSHIHSH----------------------LHLHQQDAIHAASASVHP---- 1078
Query: 1177 GHLPHPSLITPGLPSMHYPRISPTAG 1202
LI P H RI AG
Sbjct: 1079 -------LIDPLASGSHLTRIPYPAG 1097
Score = 80.1 bits (196), Expect = 1e-14
Identities = 223/1059 (21%), Positives = 350/1059 (33%), Gaps = 195/1059 (18%)
Query: 152 RENDRNLCQHLGKRKKMPKALRQLKP-GQNSCRDSDSESASGESKGFHRSSSRERLSDSS 210
R+N ++ G++K+ P +L+ G+ S + S+ G+++ +++ + R+ ++S
Sbjct: 4 RQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAS 63
Query: 211 APSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLP------------- 257
P G + S+ E + ++A + + + +L
Sbjct: 64 TPKVNKQGR-SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPR 122
Query: 258 --EHDSQDAGPIVPKISGLERSQEKSQDCCKEPI--FEPVVLKDPCPQVAQPIP-QPQTE 312
+ D++ P + +E + S + P + P L P PQ P QP+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLST--QPPQG--PPEAQLQPAPQPQVQRPPRPQSPT 368
+ P P + P PP S Q P G PP QL P V P P P
Sbjct: 183 FE-----PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGP- 235
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSA--YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
+ +A S+ P + + ++ SS S P P P +
Sbjct: 236 ----------KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL 285
Query: 427 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGS 486
++P P + P+ TP L PP P + A PP L G+ + GH
Sbjct: 286 PSAPPPANFPH------VTPNLPPP-----PALRPLNNASASPPGL--GAQPLPGH---- 328
Query: 487 TYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPF 546
L S A G PP T P
Sbjct: 329 ----------------LPSPHAMGQGMGGLPP-----------------GPEKGPTLAPS 355
Query: 547 PHAIPPTAIMPTPAPPMFDKY-----------------PTKVDPFYRHSLFHSYPPAVSG 589
PH++PP A PAPPM Y + PF SYP +
Sbjct: 356 PHSLPP-ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP- 413
Query: 590 IPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVP----HTLLQKDPRLTDPFRPMLRK 645
PPT S Q + S P G P LL PF P
Sbjct: 414 -----PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP---S 465
Query: 646 PGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLF------GAI 699
G H ++ +HHQQ+ ++Q Q + + S PP P F G+
Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ-QQQHHGNSGPPPPGAFPHPLEGGSS 524
Query: 700 HHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHS-NFLNPAAHLEPFNRPSTFTGLAAVG- 757
HH H A +L S +P G PPPH ++ + P + S + + G
Sbjct: 525 HHAHPYAMSPSLGSL--RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 758 -------------GNAFGGLGNPSVTPNS------MFGHKDGPSVQNFSNP--HEPWNRL 796
G + P+VT +S + P+ ++P P+ +
Sbjct: 583 YPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 797 HRTPPSFPT-PPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHP 855
+P ++ T PP KPG + K + P
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
Query: 856 SPAPVLP----VNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKA 911
S P LP A G S+T QI+ E + P R S K + H +
Sbjct: 703 SGLPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Query: 912 KEGHLPEKDGHGHEGRAAGE------EAKQLARVPSPY---VRTPVVESARPNSTSSREA 962
+ + G A + E +LA+ + VR + AR RE
Sbjct: 762 QSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER 821
Query: 963 EPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASM 1022
E K + + VK+ +E + + P P HR PP S+V A++
Sbjct: 822 EREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHR----PPFEPGSAV-----ATV 872
Query: 1023 PMTVGVTGIHPMNSISSLDRTRMMTPFMGISPL--------PGGERFPYPS-FHWDPIRD 1073
P +G + ++S R +M+P P PG + P+ + DP
Sbjct: 873 PPYLG-PDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAR 931
Query: 1074 PLRDPYRELDIHRRDPLGRDFLLRN---DPLHRLSTPRL 1109
RE D+ RD L F ++ +PLH + P L
Sbjct: 932 EREREARERDL--RDRLKPGFEVKPSELEPLHGVPGPGL 968
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/296 (27%), Positives = 102/296 (34%), Gaps = 56/296 (18%)
Query: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQ 379
L Q AP + P L P + P E A P P P T H P +
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 380 AHPSAQSLSQPLSAYNSSSLSLN--SLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN 437
HP PL A + L N +L SS + + + A F +
Sbjct: 901 NHP----FYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Query: 438 HSPLHSFT-PTLQP-PAHSHHPNMFAPPTALPPP-----PPLTSGSLQVAGHPAGSTYSE 490
PLH P L P P H PP P P PL L +A PA
Sbjct: 957 LEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPA------ 1010
Query: 491 QDILRQELN--TRFLAS-QSADRGASLGPPPYLRTEF-----HQHQHQHQHTHQHTHQ-- 540
LR +++ R A Q A+R A+LG P R + H HQH H H+H H HQ
Sbjct: 1011 ---LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQD 1067
Query: 541 --HTFTPFPH-------------AIP-PTAIMPTPAPPMFDKYPTKVDPFYRHSLF 580
H + H IP P +P P P +P + RH LF
Sbjct: 1068 AIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLP----HPLHENEVLRHQLF 1119
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 81.3 bits (199), Expect = 5e-15
Identities = 140/542 (25%), Positives = 173/542 (31%), Gaps = 76/542 (14%)
Query: 257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLR 316
P + A P + L P+ P + PCP P P L
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA---PCPLQAPPSPLT 577
Query: 317 APSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
P P+ T P PP L++ P QG P L P P Q PP LP
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP---------XLALP 628
Query: 377 PVQAHPSAQSLSQPLSAY-NSSSLSLNSLSSSRSSTPAKTQPAPP-HISHHPSASPFPLS 434
P+QA PS + S PLS S + N+L+ P P+PP P ASP P+S
Sbjct: 629 PLQAPPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVS 686
Query: 435 ----LPNHSPLHSFTPTLQ-PPAHSHHPNMFAPPTALPP---PPPLTSGSLQVAGHPAGS 486
P+ +P P LQ PP+ P M P+A PP PPPL + LQV P S
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPM--SPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 487 TYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPF 546
LA+ S PP L
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPS--PPASLPMS----------------------- 779
Query: 547 PHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFH---SYPPA-VSGIPPMIPPTGPFGS 602
P A PP P A P P+ F + F S P + ++ PP PP
Sbjct: 780 PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839
Query: 603 LQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYH 662
LQ P S + RP T PRLT P P +
Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 663 HQQKVKKQMQSDPHKL---DFGLKPEFLSRPPGPSLFGAIH---HPHDLARPSTLFSAAG 716
H S P +L D G + + PP + A H A P A G
Sbjct: 900 HSSSA----TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 955
Query: 717 AAHPTGTPFGP----------PPHHSNFLNPA-AHLEPFNRPSTFTGLAAVGGNAFGGLG 765
A P GP PA L+P P T G AA G A
Sbjct: 956 APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSR 1015
Query: 766 NP 767
+P
Sbjct: 1016 SP 1017
Score = 71.6 bits (174), Expect = 4e-12
Identities = 173/733 (23%), Positives = 242/733 (33%), Gaps = 94/733 (12%)
Query: 27 RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEED 86
R L A G GGA + A + S + P S P+ R R ++TS
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 87 IIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPH 146
G A + +K + + +E V + + KR AL+ G + P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 173
Query: 147 HYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERL 206
+ R R +G + P A + +P R S S SAS S ++R R
Sbjct: 174 PAMARRS--RAAGTEVGLPRPAPSA--RPRPPTEGPRKSVS-SASEHSTTEPSPAARRRP 228
Query: 207 SDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGP 266
S + S + A S + G P H SQ
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSAR-------------GTPRAPAHPSQ---- 271
Query: 267 IVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQV----AQPIPQPQTEPQLRAPSPDP 322
PK GL+ + P P KD P + + P+ P P P P
Sbjct: 272 --PKPKGLQ--------ALRPPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 323 DLVQRTEAP---PQPPPLSTQPPQGPPEAQLQPAPQ--PQVQRPPRPQSPTQLLHQNLPP 377
D T P P PPL+T P PP P+ Q P P Q+P + PP
Sbjct: 321 DNAA-TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM---TTPP 376
Query: 378 VQAHPSAQ---------SLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSA 428
+QA PS Q SL+ P S L+L+SL ++ S Q ++ P
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 429 SPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTY 488
+ L+ P+ + TP PP + P +LP PPL + SL A P S
Sbjct: 437 TQASLTSPSRP---ASTPPDSPPLQA--------PLSLPASPPLQT-SLSPAVSPLSSPL 484
Query: 489 SEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPH 548
+ + Q L++ LAS S S P L T+ Q P
Sbjct: 485 TIHPL--QALSS--LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
Query: 549 AIPP-----TAIMPTP---APPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
PP +A + TP PP P + P + P +++ PP PP
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 601 GSLQGAFQPKTS---NPIDVAARPGTVPHTLLQKDPRLTDPFRPMLR-KPGKWCAMHVHI 656
LQG P S P A +P P + P P+ P A+ VH+
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 657 AWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAG 716
+ Q P S P PS P LA P +
Sbjct: 661 LQAPFSPPPSPPVQAPFSPP----------ASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 717 AAHPTGTPFGPPP 729
A P +P PP
Sbjct: 711 PASPPMSPSATPP 723
Score = 69.7 bits (169), Expect = 2e-11
Identities = 132/541 (24%), Positives = 179/541 (33%), Gaps = 115/541 (21%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ 359
P + P T P PS P +Q AP P L T P P Q P+P +
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP---LT 577
Query: 360 RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP-- 417
PP P++P+ + PP QA P+ S PL S LS P T P
Sbjct: 578 TPP-PETPSSIA---TPPPQAPPALAS--PPLQGLPSPPLS-----------PLATPPPQ 620
Query: 418 APPHISHHP-SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGS 476
APP ++ P A P P + P SPL TP+ Q P ++ ++ P + PP PP+ +
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLA--TPSPQAP-NALAVHLLQAPFSPPPSPPVQAPF 677
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQ 536
A P + A+ + SL PP
Sbjct: 678 SPPASPPVSPS----------------ATPPSQAPPSLAAPPL----------------- 704
Query: 537 HTHQHTFTPFPHAIPP---TAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI-PP 592
P P A PP +A P APP P +V P S S P + S PP
Sbjct: 705 -----QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP----SPPASPPMSPSATPPP 755
Query: 593 MIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAM 652
+PP LQ P S P+ A+P Q P L P P+ P +
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPP------QAPPALATP--PLQALPSPPASF 807
Query: 653 HVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLF 712
+ + + P + L L PP P + P P
Sbjct: 808 PGQAPFS--PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865
Query: 713 SAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPN 772
S +G GPPP P PS+ G + G + + TP
Sbjct: 866 SVSGPRLTLALAPGPPP------------PPSRSPSS----TLSGPDLAGHSSSATSTPE 909
Query: 773 SMFGHKDGPSVQNFSNP----------HEPWNR------LHRTPPSFPTP-PPWLKPGEL 815
+ G+ GP ++P W+R R P P P PP PG
Sbjct: 910 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
Query: 816 E 816
+
Sbjct: 970 D 970
Score = 68.6 bits (166), Expect = 4e-11
Identities = 79/312 (25%), Positives = 120/312 (38%), Gaps = 59/312 (18%)
Query: 256 LPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQL 315
LP + + P P +S L ++ + + + P P V P P + P
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 316 RAPSPD----PDL----VQRTEAPPQPPPLS---TQPPQGPPEAQLQPAPQPQVQRPPRP 364
+ +P P L +Q +PP PP+S T PPQ PP P P P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746
Query: 365 QSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL--NSLSSSRSSTPAKTQPAPPHI 422
SP+ +PP+ A P Q P ++ S L+ + ++ P + P+PP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP-- 804
Query: 423 SHHPSASPF---------PLSL-PNHSPLHSFTPTLQ-PPAHSHHPNMFA---PPT---- 464
+ P +PF PL+ P +P P LQ PP+ P + A PPT
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 465 ----------AL---PPPPPLTSGSL-----QVAGHPAGSTYSEQDILRQELNTRFLASQ 506
AL PPPPP S S +AGH + +T + +++ +
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--------S 916
Query: 507 SADRGASLGPPP 518
+ GA+ PPP
Sbjct: 917 GPEGGAAASPPP 928
Score = 65.9 bits (159), Expect = 2e-10
Identities = 164/700 (23%), Positives = 228/700 (32%), Gaps = 114/700 (16%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 228
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 229 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 283
Query: 179 QNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEK 238
Q + D+ A G S + PS GT + D ++
Sbjct: 284 QVTPPRKDAAPALGPLSS----------SPLATPSPSGT-------KARPVPPPDNAATP 326
Query: 239 LFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDP 298
L T + P L LP + P P + L + P + P
Sbjct: 327 LPAT--LPPSPPLAT-PLPLAPPSPSAP--PSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 299 CPQVAQPI--PQPQTEPQLRAPSPDP--------------DLVQRTEAPPQPPPLSTQ-- 340
Q PI P T P L+AP P P +Q T + P TQ
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 341 ------PPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHP--SAQSLSQPLS 392
P PP++ AP PP S + + P+ HP + SL+
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAP-----PHISHHPSASPFPLSLPNHSPLHSFTPT 447
SSL + L + S P Q P P + + PS +P PL + +PL TP
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS-APL--TTPH 557
Query: 448 LQPPAHSHHPNMFAPPTALPPPPPLTSGSLQV---AGHPAGSTYSEQDILRQELNTRFLA 504
L+ P + APP+ L PPP T S+ PA ++ Q + L+
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 505 SQSADRGASLGP---------PPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPH------- 548
A +L P P L H Q F+P P
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 549 ------AIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI-PPMIPPTGPFG 601
+ P+A P+ APP P +V P S S P + S PP PP
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPP----SPPASPPMSPSATPPPQAPPPLAAP 733
Query: 602 SLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRP 641
LQ P S P+ +A P LL P P P
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Score = 45.8 bits (107), Expect = 3e-04
Identities = 110/511 (21%), Positives = 162/511 (31%), Gaps = 77/511 (15%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P PP S + + PP P P R P L + L A+ +
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG--KA 147
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP 450
A S+LS + + TP PA ++ A+ + LP +P P +
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPA---MARRSRAAGTEVGLPRPAPSARPRPPTEG 204
Query: 451 P-----AHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLAS 505
P + S H P A P G LQ PA + S + L+S
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPS--AGGGLQ---RPASRSLSS--------SATPLSS 251
Query: 506 QSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFD 565
+ ++ G P R H Q + + P A P A+ P + P+
Sbjct: 252 PARSGPSARGTP---RAPAHPSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLAT 306
Query: 566 KYP--TKVDPFYRHSLFHSYPP---AVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAAR 620
P TK P PP A + +P +PP+ P + P S P +
Sbjct: 307 PSPSGTKARPV---------PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Query: 621 PGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDF 680
P Q P +T P PM P + + + +Q+ P L
Sbjct: 358 PSPPATPPSQAPPSMTTP--PMQAPPSLQTIPPIQVPHSL------TSPSLQAPPSPL-- 407
Query: 681 GLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH 740
L + G A H ++ T S + P TP PP + PA+
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 741 ---------LEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHE 791
+ P + P T L A+ A S +P + P ++ S+
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLA-------SHSPQAPLSSLIMPPLETQSS--- 517
Query: 792 PWNRLHRTPPSFPTPPPWLKPGELERSASAA 822
PPS TPP L LE S A
Sbjct: 518 ------LAPPSLQTPPASLTTPPLENLPSLA 542
Score = 35.0 bits (79), Expect = 0.45
Identities = 81/359 (22%), Positives = 126/359 (35%), Gaps = 67/359 (18%)
Query: 720 PTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKD 779
P G+P PPP + PAA + A GG P P +
Sbjct: 29 PPGSPRPPPP-----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 780 GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSK 839
G S +N ++ R R PP+ T PG + A+ R + ++ +S
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNT-----SPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 840 DD-----KERESVEK--------RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 886
++ K E+ ++ R +S P+P P A + TE
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--------GLP 190
Query: 887 KDKPKERERDHSES-RKDLA-ADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV 944
+ P R R +E RK ++ A EH E AA + P
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPAS 239
Query: 945 RTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASE 1004
R+ + SA P S+ +R +G P P S+ K P+ Q R +
Sbjct: 240 RS-LSSSATPLSSPARSGPSARGTP--RAPAHPSQPK------------PKGLQALRPPQ 284
Query: 1005 PPPPNSSSSVHPGPLASMPM-TVGVTGIH------PMNSISSLDRTRMMTPFMGISPLP 1056
PP ++ GPL+S P+ T +G P N+ + L T +P + +PLP
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-TPLP 342
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 77.4 bits (189), Expect = 8e-14
Identities = 207/938 (22%), Positives = 306/938 (32%), Gaps = 195/938 (20%)
Query: 56 KEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFV--TFEALEKDVALKPQER 113
KE+ + S P P + K+ S+++ + M S T+E+ E+D KP
Sbjct: 554 KEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKC-KPMSY 612
Query: 114 VEKRQTPLTKKKREALTNGLSFHSKKSRL-----SHPHHYSSDRENDRNLCQHLGKRKKM 168
EKRQ L K G H +SR S+P D E +
Sbjct: 613 EEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK------------ 660
Query: 169 PKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQE 228
P LR+L+ SC + + + SS + S S +S+S E
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS------------ESESSSE 708
Query: 229 EKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEP 288
+SD+ E + P K R Q+K +
Sbjct: 709 SSSSDS-----------------------EDSETEMAPKSKKKGHPGREQKKHHHHHHQQ 745
Query: 289 IFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA 348
+ + P P QP P PQ P P P P Q+ + PP PPP + P Q P
Sbjct: 746 MQQA-----PAPVPQQPPPPPQQPP----PPPPP---QQQQQPPPPPPPPSMPQQAAPAM 793
Query: 349 QLQPAPQPQVQRPP-RPQSP----------TQ-LLHQNLPPVQAHPSAQSLSQPLSAYNS 396
+ P P Q P PQ P TQ +LH P + H L QP
Sbjct: 794 KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH-----LPQPPEHSTP 848
Query: 397 SSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHH 456
L+ +++ S + A Q + + P P P SP + TP L P +
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908
Query: 457 PNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGP 516
P + PP PPLTS +Q+ Y +Q + + + T L S P
Sbjct: 909 PQVLLEDEE-PPAPPLTSMQMQL--------YLQQ-LQKVQPPTPLLPSVKVQS----QP 954
Query: 517 PPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYR 576
PP L H Q Q Q P P PP P P P + P +
Sbjct: 955 PPPLPPPPHPSVQQ-----QLQQQPPPPPPPQPQPPPQQQHQPPP-----RPVHLQPM-Q 1003
Query: 577 HSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLT 636
S PP G P PP G Q P+ + P V + H + DP T
Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPPG-----QQPPPPQPAKPQQVIQHHHSPRHH--KSDPYST 1056
Query: 637 DPFRP-----MLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPP 691
R M+ P +Q HQ ++ +Q P K + +P
Sbjct: 1057 GHLREAPSPLMIHSPQM-------SQFQSLTHQSPPQQNVQ--PKKQELRAASVVQPQPL 1107
Query: 692 GPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHL--EPFNRPST 749
IH P + P + P+ P PP H + HL P +P
Sbjct: 1108 VVVKEEKIHSPIIRSEPFS---------PSLRP--EPPKHPESIKAPVHLPQRPEMKPV- 1155
Query: 750 FTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPW 809
+G P + P QN P P + P P P
Sbjct: 1156 -------------DVGRPVIRPPE----------QNAPPPGAPDKDKQKQEPKTPVAPK- 1191
Query: 810 LKPGELERSASAAA----HDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNA 865
K +++ S A+ H + SS S + R + EK A
Sbjct: 1192 -KDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQA----- 1245
Query: 866 LGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHE 925
H E++R ++D ++ R H E+R+ + + +E
Sbjct: 1246 -EHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQE------------ 1292
Query: 926 GRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 963
++ +Q A V + TP +S++P S ++ E
Sbjct: 1293 --QQQQQQQQAAAVAA--AATPQAQSSQPQSMLDQQRE 1326
Score = 47.8 bits (112), Expect = 7e-05
Identities = 112/542 (20%), Positives = 180/542 (33%), Gaps = 106/542 (19%)
Query: 201 SSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSE--KLFNTVIVNKDPELGVGTLPE 258
SS + SDSS+ S T DS+ ++ ++ ++ + + + P+ E
Sbjct: 484 SSSDSSSDSSSDSDSSTD---DSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 259 HDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEP----------VVLKDPCPQVAQPIP- 307
D ++ K E +E + KEP + V K+P P ++P P
Sbjct: 541 KDKKEKKK--EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPT 598
Query: 308 ---------QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQ----GPPEAQ----- 349
+P + + R S D + + + + ++ P P E +
Sbjct: 599 YESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFET 658
Query: 350 LQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
L+P+ +++R T L + P + S + ++SS +S SSS
Sbjct: 659 LKPSTLRELER-----YVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSD 713
Query: 410 STPAKTQPAPP--------------HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
S ++T+ AP H HH P +P P P QPP
Sbjct: 714 SEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP----PPPQQPPPPPP 769
Query: 456 HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLG 515
PP PPPPP Q A
Sbjct: 770 PQQQQQPPP--PPPPP-------------------------------SMPQQAAPAMKSS 796
Query: 516 PPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTP-APPMFDKYPTKVDPF 574
PPP++ T+ + Q + F P H P +P P PP + P P
Sbjct: 797 PPPFIATQVPVLEPQLPGS-------VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP 849
Query: 575 YRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPR 634
+ + PPA+ P P+ P + A PK + P V+ + T L P
Sbjct: 850 HLNQHAVVSPPALHNALPQ-QPSRP-SNRAAALPPKPARPPAVSP---ALTQTPLLPQPP 904
Query: 635 LTDPFRPMLRKPGKWCAMHVHIAWQIYHHQ-QKVKKQMQSDPHKLDFGLKPEFLSRPPGP 693
+ P + +L + Q+Y Q QKV+ P P L PP P
Sbjct: 905 MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHP 964
Query: 694 SL 695
S+
Sbjct: 965 SV 966
Score = 45.1 bits (105), Expect = 4e-04
Identities = 45/165 (27%), Positives = 55/165 (33%), Gaps = 33/165 (20%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQ-PPQGPPEAQLQPAPQP 356
P Q QP P P P+ PDL+ +T PP Q PP PP+ Q PAP P
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAP 265
Query: 357 QVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQ 416
Q PVQ+HP P+ A + ++ T T
Sbjct: 266 Q-------------------PVQSHP-------PIIAATPQPVKTKKGVKRKADTTTPTT 299
Query: 417 PAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP----PAHSHHP 457
P H PS P P + S P P P HP
Sbjct: 300 IDPIH--EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
Score = 36.6 bits (83), Expect = 0.16
Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 48/196 (24%)
Query: 801 PSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPV 860
P+ P P + P S+S ++ D D D DS + + E E+ + H
Sbjct: 471 PAVPPPTKVVAPPSSSDSSSDSSSDSDSSTD--DSEEERAQRLAELQEQLKAVH------ 522
Query: 861 LPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKD 920
EQ+ A +++KPK++E+D E +K ++HK KE
Sbjct: 523 -------------EQLAA---LSQPQQNKPKKKEKDKKEKKK----EKHKRKE------- 555
Query: 921 GHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGE--PAYENPK--K 976
E K A+ P P +T S+ N S +E P K + P YE+ + K
Sbjct: 556 -------EVEENKKSKAKEPPP-KKTKKNNSSNSN-VSKKEPAPMKSKPPPTYESEEEDK 606
Query: 977 SSEVKVKEERKEDHDL 992
+ +E+R+ D+
Sbjct: 607 CKPMSYEEKRQLSLDI 622
Score = 35.8 bits (81), Expect = 0.26
Identities = 62/282 (21%), Positives = 98/282 (34%), Gaps = 31/282 (10%)
Query: 968 EPAYENPKKSSEVKVKEERKEDHDLPPEAPQT--HRASEPPPP-----NSSSS----VHP 1016
+P PKK + K KE++KE H E + +A EPPP NSS+S P
Sbjct: 530 QPQQNKPKKKEKDK-KEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEP 588
Query: 1017 GPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGE--RFPYPSFHWDPIRDP 1074
P+ S P + S + R ++ + I+ LPG + R + +P
Sbjct: 589 APMKSKPPPTYESEEEDKCKPMSYEEKRQLS--LDINKLPGEKLGRVVHIIQSREPSLKN 646
Query: 1075 LRDPYRELDIHRRDPLGRDFLLR--NDPLHRLSTPRLYEAD--------RSFRDREPHDY 1124
E+D P L R L + P+ + D + F E
Sbjct: 647 SNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 1125 SHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSL 1184
S + + ++ GH ++ H + H + PA + P P
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKH----HHHHHQQMQQAPAPVPQQPPPPPQ 762
Query: 1185 ITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIST 1226
P P + P + + P A S+PPP I+T
Sbjct: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAAP-AMKSSPPPFIAT 803
Score = 33.9 bits (76), Expect = 1.0
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 22/116 (18%)
Query: 289 IFEPVVLKDPCPQVAQPIPQP-------QTEPQLRAPSPDPDLVQR-------TEAPPQP 334
+ P L+ P P QP P P Q+ P + A +P P ++ T P
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
Query: 335 PPLSTQPPQGPPEAQLQPAPQ-PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQ 389
P+ +PP PPE + Q + RP +P +++P Q HP+ + S+
Sbjct: 301 DPIH-EPPSLPPEPKTTKLGQRRESSRPVKPPK------KDVPDSQQHPAPEKSSK 349
Score = 31.2 bits (69), Expect = 6.5
Identities = 41/162 (25%), Positives = 56/162 (34%), Gaps = 43/162 (26%)
Query: 327 RTEAPPQPPPLSTQP----PQGPPEAQLQPAPQPQVQRPPRP-QSPTQLLHQNLPPVQAH 381
R E P +ST P PP+ Q P VQ P P + T L P +
Sbjct: 183 RKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV 242
Query: 382 PSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPL 441
P QPL ++ P QP PP +P P + +H P+
Sbjct: 243 P-----PQPL----------------QTPPPVPPQPQPP-------PAPAPQPVQSHPPI 274
Query: 442 HSFTPT-------LQPPAHSHHPNMFAP---PTALPPPPPLT 473
+ TP ++ A + P P P +LPP P T
Sbjct: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTT 316
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 76.6 bits (187), Expect = 1e-13
Identities = 132/550 (24%), Positives = 190/550 (34%), Gaps = 81/550 (14%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 118 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 178 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 219
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 220 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 274
Query: 179 QNSCRDSDSESASGE-SKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSE 237
Q + D+ A G S + S SAP SL T + + S S
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 238 KLFNTVIVNKDPELGVGT----------LPEHDSQDAGPIVPKISGLERSQEKSQDCCKE 287
+ P + T LP + + P P +S L ++ +
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPP-LSTQPPQGPP 346
+ + P P V P P + P +PS P P Q PP L+ P Q PP
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPV--SPSATP--------PSQAPPSLAAPPLQVPP 444
Query: 347 EAQLQPAPQPQVQRPPRPQSPTQL--LHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P P PP+ P L PP QA P+ + PL A S S
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL--ATPPLQALPSPPASFPGQ 502
Query: 405 S--SSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQ----PPAHSHHPN 458
+ S +S P PP + A+P L +P P +PTLQ PP +
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPA---SPTLQAPRRPPTPGPDTS 558
Query: 459 MFAPPTAL-----PPPPPLTSGSL-----QVAGHPAGSTYSEQDILRQELNTRFLASQSA 508
+ P L PPPPP S S +AGH + +T + +++ +
Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--------SGP 610
Query: 509 DRGASLGPPP 518
+ GA+ PPP
Sbjct: 611 EGGAAASPPP 620
Score = 51.6 bits (122), Expect = 5e-06
Identities = 79/329 (24%), Positives = 108/329 (32%), Gaps = 59/329 (17%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P P P + + P P P + P + P + + PS + +P
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Query: 391 LSAYNSSSLSLNSLSSSRS--STPAKTQPAP---PHISHHPSASPFPLSLPNHSPLHSFT 445
+ + SLSSS + S+PA++ P+ P HPS P P L P
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRP----- 273
Query: 446 PTLQPPAHSHHPNM-------FAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQEL 498
P + PP P + A P+ PP P SLQ P + S+
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA------- 326
Query: 499 NTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPT 558
T L S + S P P L TP P A P A+ P
Sbjct: 327 -TTSLGSPTLQATHSFLPSPPLSP-------------------LATPPPQAPPALALPPL 366
Query: 559 PAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI------PPMIPPTGPFGSLQGAFQPKTS 612
APP P + P S P A + + P PP P +Q F P S
Sbjct: 367 QAPPSPPASP-PLSPLATPS-----PQAPNALAVHLLQAPFSPPPSP--PVQAPFSPPAS 418
Query: 613 NPIDVAARPGTVPHTLLQKDPRLTDPFRP 641
P+ +A P + L P P P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPP 447
Score = 31.2 bits (69), Expect = 6.5
Identities = 58/271 (21%), Positives = 84/271 (30%), Gaps = 50/271 (18%)
Query: 800 PPSFPTPPPWLKPGELERSASAAAHDRDRDVDKR----------------DSSVSKDDKE 843
PP P PPP + P L +A A R ++ + S+
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88
Query: 844 RESVEKRHSSHPSPAPV-LPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRK 902
+ + SP PV P A G TR ++ + + R
Sbjct: 89 GRGERAPPAKNTSPGPVSSPGRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRS 145
Query: 903 DLAADEHKAKEGHLP--EKDGHGHEGRAAGEEAKQLARVPSPYVRTPV------VESARP 954
L+A + G P RAAG E PS R P V SA
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205
Query: 955 NSTSSREAEPRKGEPA------------------YENPKKSSEVKVKEERKEDHDLPPEA 996
+ST+ R+ A +P +S R H P+
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK- 264
Query: 997 PQTHRASEPP---PPNSSSSVHPGPLASMPM 1024
P+ +A PP PP ++ GPL+S P+
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 73.2 bits (178), Expect = 1e-12
Identities = 97/373 (26%), Positives = 129/373 (34%), Gaps = 97/373 (26%)
Query: 256 LPEHDSQDAGPIVPKISGLERSQ--EKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEP 313
L + S P VP++ + SQ E SQ K+P +P + P Q +P PQP +
Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQ-QPAQQQQPAQQPKKPSPQPSSPR 331
Query: 314 QLRAP---SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ------RPPRP 364
Q++ SP + PP+ P + T P PP A P +P + PP P
Sbjct: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP-AHPPPDRKPPLAAALGEAEPPGP 390
Query: 365 QSPTQLLHQNLPPVQAHPSAQSLSQPL---------SAYNSSSLSLNSLSSSRS--STPA 413
T L +PP AHP+ PL S+Y + + +S S S +
Sbjct: 391 VDATDLPKVQIPP-PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQS 449
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLT 473
+ P P A P LP H H + P PP P F PP A+PPP P
Sbjct: 450 MMKTEGPSYGALPPAYGPPAHLPYHP--HVYPPNPPPPPVPPPPASFPPP-AIPPPTP-- 504
Query: 474 SGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQH 533
G+P PPP
Sbjct: 505 -------GYPP-------------------------------PPP--------------- 511
Query: 534 THQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPP-AVSGIPP 592
T+ F P P +PPT +P PP P P + PP +PP
Sbjct: 512 ----TYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPP-------PAVPPGGQPPVPP 560
Query: 593 MIPPTG--PFGSL 603
IPP G P G L
Sbjct: 561 PIPPPGMPPVGGL 573
Score = 62.0 bits (149), Expect = 3e-09
Identities = 84/329 (25%), Positives = 117/329 (35%), Gaps = 72/329 (21%)
Query: 294 VLKDPCPQVAQPIPQPQ------TEPQLRAP---SPDPDLVQRTEAPPQPPPLSTQPPQG 344
VL+D C Q+ Q + T QL+ P P P + Q ++ P +QP Q
Sbjct: 246 VLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQK 305
Query: 345 PPEA---QLQPAPQPQVQRPPRPQSPTQLLHQNL-----------PPVQAHPSAQSLSQP 390
P+ Q QPA QP+ + P+P SP Q+ + PP P ++ P
Sbjct: 306 DPQQPAQQQQPAQQPK-KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP 364
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP 450
L + L+++ P P + P P + P +P+H QP
Sbjct: 365 LPPAHPPPDRKPPLAAALGEA---EPPGPVDATDLPKVQIPPPAHP--APVH------QP 413
Query: 451 PAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADR 510
P H P PP PPP +G + + +G Y L S
Sbjct: 414 PPLPHRP----PP---PPPSSYMTGMSTTSSYMSGEGYQS------------LQSMMKTE 454
Query: 511 GASLG--PPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYP 568
G S G PP Y H H H + P P PP + P PP YP
Sbjct: 455 GPSYGALPPAY-------GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYP 507
Query: 569 TKVDPFYRHSLFHSYPPAVSGIPPMIPPT 597
P Y ++PP PP +PPT
Sbjct: 508 PP-PPTYN----PNFPPP----PPRLPPT 527
Score = 41.6 bits (96), Expect = 0.005
Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 44/169 (26%)
Query: 935 QLARVPS--PYVRTPVVESARPNSTSSREAEPRKGEPAY--------ENPKKSSE----- 979
QL + PS P + P V+ ++P S SS ++P++ +P + PKK S
Sbjct: 272 QLQQPPSLQPTPQVPQVQQSQP-SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
Query: 980 --------VKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGI 1031
V KEE K PP+ P+ P PP HP P P+ +
Sbjct: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP-----AHPPPDRKPPLAAALGEA 385
Query: 1032 HPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1080
P + + D ++ P P H P+ P P+R
Sbjct: 386 EPPGPVDATDLPKVQIP---------------PPAHPAPVHQPPPLPHR 419
Score = 32.3 bits (72), Expect = 2.9
Identities = 76/333 (22%), Positives = 105/333 (31%), Gaps = 59/333 (17%)
Query: 513 SLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIP---PTAIMPTPAPPMFDKYPT 569
SL P P + Q Q + P P P P P+ P K
Sbjct: 278 SLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAV 337
Query: 570 KVDPFYRHSLFHSYPPAVSGI-------PPMIPPTG---PFGSLQGAFQPKTSNPID--- 616
V P + PP + I PP PP P + G +P P+D
Sbjct: 338 VVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP--GPVDATD 395
Query: 617 ---VAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCA-MHVHIAWQIYHHQQKVKKQMQ 672
V P P + Q P P RP P + M ++ Q ++ M+
Sbjct: 396 LPKVQIPPPAHPAPVHQPPPL---PHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMK 452
Query: 673 SDPHKLDFGLKPEFLSRPPG----PSLFGAIHHPHDLARPSTLFSAAGAAHPT-GTPFGP 727
++ +G P P P ++ P + P F PT G P P
Sbjct: 453 TEGPS--YGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPP 510
Query: 728 PPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFS 787
P ++ NF P L P + AV + GLG P ++
Sbjct: 511 PTYNPNFPPPPPRLPPTH---------AVPPHPPPGLGLPPA---------------SYP 546
Query: 788 NPHEPWNRLHRTPPSFPTPPPWLKP-GELERSA 819
P P PP P PPP + P G L R+A
Sbjct: 547 PPAVPPGGQPPVPP--PIPPPGMPPVGGLGRAA 577
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 70.9 bits (172), Expect = 7e-12
Identities = 104/422 (24%), Positives = 145/422 (34%), Gaps = 60/422 (14%)
Query: 252 GVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVA---QP--- 305
G G+ DSQ + V S + + +Q C P+ E VL P + QP
Sbjct: 619 GQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA 678
Query: 306 -------IPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQ-----LQPA 353
+P P P L+ PDP + PP P+ T P Q P Q QP
Sbjct: 679 PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPT 738
Query: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
P PQV P+P P Q + +LPP A S L L L + P
Sbjct: 739 PLPQV-LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL----AQVPP 793
Query: 414 KTQPAP--PHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
+ P P P I+ P +LP+ L + T PP P + P A P PP
Sbjct: 794 QMPPIPVVPPITPLAGIDGLPPALPD---LPTATVPPVPPPQYFSPAVILPSLAAPLPPA 850
Query: 472 LTSGSLQVA--GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQH 529
+ LQ HP G+ L T + + ++ PP H
Sbjct: 851 SPALPLQAVKLPHPPGAP------LAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVA 904
Query: 530 QHQHTHQHTHQHTFTPFPHAIP---PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPA 586
Q +P A P PT + P+P + + T P + PP
Sbjct: 905 QLPGQ---------PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQP--------ALPPQ 947
Query: 587 VSGIPPMIPPTGPFGSLQGAFQPKTSNPID--VAARPGTVPHTLLQKDPRLTDPFRPMLR 644
+ P + P P Q P+ + P + +P P +L P L P RP
Sbjct: 948 PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL--PVRPEPL 1005
Query: 645 KP 646
+P
Sbjct: 1006 QP 1007
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 41/178 (23%)
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQG--PPEAQLQPAP-- 354
Q P PQ P PSP + PPQP PP T PPQ PP+ L P P
Sbjct: 909 QPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVL 968
Query: 355 QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAK 414
PQ RPP+P P Q + LPP P +L P +
Sbjct: 969 PPQPTRPPQPVLPPQPM---LPPQPVLPPQPAL------------------------PVR 1001
Query: 415 TQPAPPHISHH--PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
+P PH+ P+A+P L H ++ Q P + PP A+ PP
Sbjct: 1002 PEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQV------PTVPVPPAAVLSPP 1053
Score = 48.9 bits (115), Expect = 3e-05
Identities = 82/347 (23%), Positives = 109/347 (31%), Gaps = 66/347 (19%)
Query: 220 FCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQE 279
F + D +KA D SE + D GT P H S GL +E
Sbjct: 1246 FIEQMKDVMDKAEDMLSED------TDADRGSDPGTSPPHLST---------CGLGTGEE 1290
Query: 280 KSQDCCKEPIFEPVVLKDP------CPQVAQPIPQ-PQTEPQLRAPSPDPDLVQRTEA-- 330
Q P+++ VL CP P P+ P++ P L S P+ Q +
Sbjct: 1291 SRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYK 1350
Query: 331 -------------------------PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQ 365
PP PP P P A Q P P P
Sbjct: 1351 DQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPA 1410
Query: 366 SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL--------------SSSRSST 411
S T Q S SQPL+ + + L++ L S+ +S
Sbjct: 1411 SGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASA 1470
Query: 412 PAKTQPAP-PHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
P + P P P S H S +P P +L +PL A S P+ PT P PP
Sbjct: 1471 PREPLPPPAPEPSPH-SGTPQP-ALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPP 1528
Query: 471 PLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPP 517
+ G S L ++L T AS G P
Sbjct: 1529 SALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTP 1575
Score = 42.0 bits (97), Expect = 0.004
Identities = 53/171 (30%), Positives = 70/171 (40%), Gaps = 33/171 (19%)
Query: 287 EPIFEPVVLKDPCPQVA-QPI--PQPQTEPQLRAPSPDPDLVQRTEAPPQPP-PLSTQP- 341
+P P + P P + QP+ PQP PQ P P P L + PPQP P+ +P
Sbjct: 947 QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP-PQPMLPPQPVLPPQPALPVRPEPL 1005
Query: 342 ---------PQGPPEAQL---QPAP---QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQS 386
P P +Q+ PAP Q P P P +L LP V + +
Sbjct: 1006 QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPEL 1065
Query: 387 LSQPLSAYNSSSLSLNSLSSSRSSTPAKT----QPAPPHISHHPS-ASPFP 432
L Q S SL ++S+S S P +T PA P + P ASP P
Sbjct: 1066 LPQFPS-------SLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCP 1109
Score = 33.5 bits (75), Expect = 1.3
Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 5/69 (7%)
Query: 1172 PASLDGHLPHPSL-ITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGR 1230
P SL H P P++ P LP P PT Q + PP L+ P PL L +
Sbjct: 692 PPSLQQHFPDPAMSFAPVLPPPSTPM--PTGPGQPAPPGQQPPP--LAQPTPLPQVLAPQ 747
Query: 1231 PVSPRRTTP 1239
PV P + P
Sbjct: 748 PVVPLQPVP 756
Score = 32.0 bits (71), Expect = 3.8
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 1179 LPHPSLITPGLP-SMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRT 1237
LPHP PG P +M I P A LL PP A + ++ L G+PV P
Sbjct: 861 LPHP----PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAF 916
Query: 1238 TPLSAEIRERPPSHTLKDIEA 1258
++ P HT++++ A
Sbjct: 917 PQMAPTDVPPSPHHTVQNMRA 937
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 67.4 bits (163), Expect = 8e-11
Identities = 134/580 (23%), Positives = 193/580 (33%), Gaps = 111/580 (19%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 228
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 229 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 283
Query: 179 QNSCRDSDSESASGESKGF-----------------------HRSSSRERLS-------- 207
Q + D+ A G H SS +L+
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 208 DSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGT----------LP 257
SAP SL T + + S S + P + T LP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 258 EHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRA 317
+ + P P +S L ++ + + + P P V P P + P +
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV--S 461
Query: 318 PSPDPDLVQRTEAPPQPPP-LSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQL--LHQN 374
PS P P Q PP L+ P Q PP P P PP+ P L
Sbjct: 462 PSATP--------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 375 LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLS--SSRSSTPAKTQPAPPHISHHPSASPFP 432
PP QA P+ + PL A S S + S +S P PP + A+P
Sbjct: 514 KPPPQAPPAL--ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL- 570
Query: 433 LSLPNHSPLHSFTPTLQ----PPAHSHHPNMFAPPTAL-----PPPPPLTSGSL-----Q 478
L +P P +PTLQ PP ++ P L PPPPP S S
Sbjct: 571 LQVPPSPPA---SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 627
Query: 479 VAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPP 518
+AGH + +T + +++ + + GA+ PPP
Sbjct: 628 LAGHSSSATSTPEELRGYD--------SGPEGGAAASPPP 659
Score = 65.9 bits (159), Expect = 2e-10
Identities = 125/491 (25%), Positives = 158/491 (32%), Gaps = 99/491 (20%)
Query: 301 QVAQPIPQPQTEPQLRAPSPD-PDLVQRTEAPPQPPPLSTQPPQGPPEAQLQ----PAPQ 355
Q+A P+P L PSP P +Q +PP PP G P Q P+P
Sbjct: 333 QLATPLP-------LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385
Query: 356 PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL-NSLSSSRSSTPAK 414
P PQ+P L LPP+QA PS + S PLS + S N+L+ P
Sbjct: 386 LSPLATPPPQAPPALA---LPPLQAPPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 415 TQPAPPHISHHPSASPF-PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLT 473
P+PP +PF P + P SP S TP Q P P++ APP +PP PP +
Sbjct: 442 PPPSPP------VQAPFSPPASPPVSP--SATPPSQAP-----PSLAAPPLQVPPSPPAS 488
Query: 474 SGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQH 533
A P + PPP + Q
Sbjct: 489 PPMSPSATPPPQA-----------------------------PPPLAAPPLQLAKPPPQ- 518
Query: 534 THQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPM 593
P A PP +P+P +P + PF + P A PP
Sbjct: 519 ----------APPALATPPLQALPSPPA----SFPGQA-PFSPSASLPMSPLATP--PPQ 561
Query: 594 IPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMH 653
PP LQ P S + RP T PRLT P P
Sbjct: 562 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 654 VHIAWQIYHHQQKVKKQMQSDPHKL---DFGLKPEFLSRPPGPSLFGAIH---HPHDLAR 707
+ H S P +L D G + + PP + A H A
Sbjct: 622 TLSGPDLAGHSSSA----TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677
Query: 708 PSTLFSAAGAAHPTGTPFGP----------PPHHSNFLNPA-AHLEPFNRPSTFTGLAAV 756
P A GA P GP PA L+P P T G AA
Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737
Query: 757 GGNAFGGLGNP 767
G A +P
Sbjct: 738 GAGAGASSRSP 748
Score = 65.5 bits (158), Expect = 3e-10
Identities = 128/508 (25%), Positives = 172/508 (33%), Gaps = 73/508 (14%)
Query: 27 RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEED 86
R L A G GGA + A + S + P S P+ R R ++TS
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 87 IIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPH 146
G A + +K + + +E V + + KR AL+ G + P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 173
Query: 147 HYSSDRENDRNLCQHLGKRKKMPKAL-RQLKPGQNSCRDSDSESASGESK---------- 195
+ R R +G + P A R G S SE ++ E
Sbjct: 174 PAMARRS--RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 196 -GFHRSSSRERLSDS--------SAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
G R +SR S + S PS+ GT S + K A
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPR 289
Query: 247 KDPELGVGTLPEHDSQDAGPIVPKISG----LERSQEKSQDCCKEPIFEPVVLKDPCPQV 302
KD +G L P S L + S C+ + P+ L P P
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ--LATPLPLAPPSPSA 347
Query: 303 A---QPIPQPQTEPQLRAPSP--DPDLVQRTEAPPQPP--PLSTQPPQGPPEAQLQP--- 352
Q +P P P +A + P L P PP PL+T PPQ PP L P
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 353 APQPQVQRP------PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSS 406
P P P P PQ+P L L + P + + P S S +S
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS------ 461
Query: 407 SRSSTPAKTQP--APPHISHHP-SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPP 463
P+ T P APP ++ P P P + P SP S TP Q P P + APP
Sbjct: 462 -----PSATPPSQAPPSLAAPPLQVPPSPPASPPMSP--SATPPPQAP-----PPLAAPP 509
Query: 464 TALPPPPP-----LTSGSLQVAGHPAGS 486
L PPP L + LQ P S
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPAS 537
Score = 55.1 bits (131), Expect = 4e-07
Identities = 89/356 (25%), Positives = 126/356 (35%), Gaps = 53/356 (14%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQ--PPQGPPEAQLQPAPQ 355
P P +A+ TE L P+P TE P + +++ + P A+ +P+
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 356 PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAK 414
+QRP +S + P ++ PSA+ + P L +L + + P K
Sbjct: 232 GGLQRPAS-RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 415 -TQPAPPHISHHPSASPFP-LSLPNHSPLHSFTPTLQPPAHSHHPN-MFAPPTALPPPPP 471
PA +S P A+P P +L + +P PTL HS A P L PP P
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAP-----PTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH 531
SLQ P + S+ T L S + S P P L
Sbjct: 346 SAPPSLQTLPSPPATPPSQA--------TTSLGSPTLQATHSFLPSPPLSP--------- 388
Query: 532 QHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI- 590
TP P A P A+ P APP P + P S P A + +
Sbjct: 389 ----------LATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPS-----PQAPNALA 432
Query: 591 -----PPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRP 641
P PP P +Q F P S P+ +A P + L P P P
Sbjct: 433 VHLLQAPFSPPPSP--PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Score = 34.7 bits (78), Expect = 0.59
Identities = 71/320 (22%), Positives = 110/320 (34%), Gaps = 59/320 (18%)
Query: 720 PTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKD 779
P G+P PPP + PAA + A GG P P +
Sbjct: 29 PPGSPRPPPP-----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 780 GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSK 839
G S +N ++ R R PP+ T PG + A+ R + ++ +S
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNT-----SPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 840 DD-----KERESVEK--------RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 886
++ K E+ ++ R +S P+P P A + TE
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--------GLP 190
Query: 887 KDKPKERERDHSES-RKDLA-ADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV 944
+ P R R +E RK ++ A EH E AA + P
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPAS 239
Query: 945 RTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASE 1004
R+ + SA P S+ +R +G P P S+ K P+ Q R +
Sbjct: 240 RS-LSSSATPLSSPARSGPSARGTP--RAPAHPSQPK------------PKGLQALRPPQ 284
Query: 1005 PPPPNSSSSVHPGPLASMPM 1024
PP ++ GPL+S P+
Sbjct: 285 VTPPRKDAAPALGPLSSSPL 304
Score = 33.1 bits (74), Expect = 1.7
Identities = 78/342 (22%), Positives = 106/342 (30%), Gaps = 59/342 (17%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P PP S + + PP P P R P L + L + A + + +
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL-RISAEETV-ARGKA 147
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISH-----------HPSASPFPLSLPNHS 439
A S+LS + + TP PA S PSA P P P
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP---PTEG 204
Query: 440 PLHSFT-----PTLQP-PAHSHHP------------NMFAPPTALPPPP---PLTSGSLQ 478
P S + T +P PA P ++ + T L P P G+ +
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 479 VAGHPAGSTYSEQDILRQ---------------ELNTRFLASQSADRGASLGPPPYLRTE 523
HP+ LR L++ LA+ S PP L
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT 324
Query: 524 FHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPT-PAPPMFDKYPTKVDPFYR--HSLF 580
H Q T P P A P +P+ PA P + P + HS
Sbjct: 325 PHSSSLTCQLA---TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 581 HSYP-PAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARP 621
S P ++ PP PP LQ P S P+ A P
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 65.5 bits (158), Expect = 3e-10
Identities = 93/388 (23%), Positives = 142/388 (36%), Gaps = 91/388 (23%)
Query: 275 ERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTE---PQLRAPSPDPDLVQRTEAP 331
++ Q++ Q +P + ++ P P +Q +PQ + Q P P P
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ-------- 306
Query: 332 PQPPPLSTQPPQGPPEAQLQP-----------------------APQPQVQRPPRPQSPT 368
QPP QP Q PP++Q QP AP Q P +PQ
Sbjct: 307 -QPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ--- 362
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSA 428
+ Q VQ +AQ ++ + SS L+S S + ++ P PP S P
Sbjct: 363 --VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 420
Query: 429 SPFPLSLPNH--------SPLHSFTPTLQP-----PAHSHHPNMFAPPTALPPPPPLTSG 475
P S PN SP SF P+ P P + P F+ P+ P P+
Sbjct: 421 ---PSSQPNSNVSSGPAPSP-SSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 476
Query: 476 SLQVAGHPAGSTYSEQ--------------DILRQELNTRFLASQSADRGASLG------ 515
S+ PAGS+ +E+ + LR+ +N ++ DR L
Sbjct: 477 SVM---SPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINK---IDKNEDRKKDLSKMKSLL 530
Query: 516 ---PPPYLRTEFHQHQHQHQHTHQHTHQHTF-TPFPHAIPPTAIMPTPAPPMFDKYPTKV 571
P R Q + + TP P +PPT P+ D +
Sbjct: 531 DILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTK-QQYLCQPLLDAVLANI 589
Query: 572 -DPFYRHSLFHSYPPAVSGI--PPMIPP 596
P + HSL+ ++ PA++ I PP+ P
Sbjct: 590 RSPVFNHSLYRTFVPAMTAIHGPPITAP 617
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 65.5 bits (158), Expect = 3e-10
Identities = 105/462 (22%), Positives = 158/462 (34%), Gaps = 91/462 (19%)
Query: 12 KKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPR 71
+ RRSRS R RRS L SSS S + PP P R
Sbjct: 337 RHRRSRSPVRRRRRSSASLSG-----------------SSSSSSSSRSRSPPKKPPKRTS 379
Query: 72 -PPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTK--KKREA 128
PPR+ RR S SA P R + P T K R +
Sbjct: 380 SPPRKTRRLSPSAS-------------------------PPRRRHRPSPPATPPPKTRHS 414
Query: 129 LTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE 188
T S ++KSR+S S + +H G K+ + KP + +S+ E
Sbjct: 415 PTPQQSNRTRKSRVS-----VSPGRTSGKVTKHKGTEKRESPSPAP-KPRKVELSESE-E 467
Query: 189 SASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKD 248
G+ R + + SS +G S+ ++ +++ + E
Sbjct: 468 DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE----------- 516
Query: 249 PELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQ 308
VG H + P+ E S + P P + P A P +
Sbjct: 517 ----VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP---PPTRRRRSPSPAPPPRR 569
Query: 309 ---PQTEPQLRAPSPDPDL-----------VQRTEAPPQPPPLSTQPPQGPPEAQLQPAP 354
P P+ R PSP P +QR +P PP T P PP+ + P+P
Sbjct: 570 RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP 629
Query: 355 QPQ---VQRPPRPQSPTQLLHQNLPPVQA-HPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P+ PP Q + + + P + + H S S+ S + S R
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHS--PLHSFTPTLQP 450
P +T +PP + S+SP P+ S P+ + T +P
Sbjct: 690 AP-QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Score = 58.5 bits (140), Expect = 4e-08
Identities = 111/461 (24%), Positives = 166/461 (36%), Gaps = 45/461 (9%)
Query: 52 SGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQ 111
S S + + S +PS RP RR R S S + + P
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR--RMPPP 335
Query: 112 ERVEKRQTPLTKKKR-EALTNGLSFHSKKSR-----LSHPHHYSSDRENDRNLCQHLGKR 165
R + ++P+ +++R A +G S S SR P SS R L
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395
Query: 166 KKM----------PKALRQLKPGQ-NSCRDSDSESASGESKG--FHRSSSRERLSDSSAP 212
++ PK P Q N R S + G + G + +R S S AP
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP 455
Query: 213 SSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKIS 272
+S+ D+ K + A S + ++ + + S+D P
Sbjct: 456 KPRKV-ELSESEEDKGGKMAAADSVQQ-RRQYRRQNQQSSSDSGSSSSSEDERP------ 507
Query: 273 GLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP 332
+RS K+ + + P P P+ Q P+ + R+PSP P +R+ + P
Sbjct: 508 --KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR-RRRSPSPPPTRRRRSPS-P 563
Query: 333 QPPPLSTQPPQGPPEAQL-QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPL 391
PPP + P PP + P P+ + P R P Q + PP P ++ S P
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----PKRRTASPPP 619
Query: 392 SAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPL--SLPNHSPLHSFTPTLQ 449
+S S S P K + +P PS S S P+ S + +P Q
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP--Q 677
Query: 450 P-PAHSHHPNMFAPPTALPPPPPL--TSGSLQVAGHPAGST 487
P HS P AP T+ PPP S S Q P+ ST
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718
Score = 48.9 bits (115), Expect = 3e-05
Identities = 99/470 (21%), Positives = 157/470 (33%), Gaps = 98/470 (20%)
Query: 162 LGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFC 221
L K + + + Q K +D D + E K SSRE+ S +P
Sbjct: 126 LKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEK----ESSREKRERSRSP--------- 172
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
+ K+ S + + V ++ + P H ++ P P E++ E
Sbjct: 173 -----RRRKSRSPSPRRRSSPV--RRERKRSHSRSPRHRTKSRSPS-PAPEKKEKTPELP 224
Query: 282 QDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP------ 335
+ K + EP V + +P+P+ P+ + PSP+ + + E P
Sbjct: 225 EPSVK--VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 336 ----------PLSTQPPQG--PPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPS 383
P T+P + P +P +R P P+ T + +PP H
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP--PRRMPPPPRHRR 340
Query: 384 AQSLSQPLSAYNSSSLSLN----SLSSSRSSTPAKTQP-----------------APPHI 422
++S P+ SS SL+ S SSSRS +P K P +PP
Sbjct: 341 SRS---PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397
Query: 423 SHHPSASPFPLSLPNHSPLH-----------SFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
H PS P HSP S +P + H + P P P
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ-SADRGASLGPPPYLRTEFHQHQHQ 530
L + G + D ++Q R Q S+D G+S H +
Sbjct: 458 -RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516
Query: 531 HQHTHQHTHQHTFTPFPH----------------AIPPT--AIMPTPAPP 562
+H+ + +P P + PPT P+PAPP
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP 566
Score = 48.1 bits (113), Expect = 5e-05
Identities = 50/227 (22%), Positives = 83/227 (36%), Gaps = 33/227 (14%)
Query: 810 LKPGELERSASAAAHDRDRDVDKRDSSVSKDDKER----ESVEKRHSSHPSP----APVL 861
+K ++E+ A+ +D D DKRD + +E+ S +R S PSP +PV
Sbjct: 131 IKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
Query: 862 PVNALGHTRSSTEQIRAHLNTEAREK-------DKPKERERDHSESRKDLAADEHKA-KE 913
H+RS + ++ + A EK +P + ++ S +D K K
Sbjct: 191 RERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKP 250
Query: 914 GHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 973
+PE E + E+ K+ R R S S + R P++
Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTR-------------PRSRSRSKSRSRTRSRSPSHTR 297
Query: 974 PKKSSEVKVKEERKEDHDLPPEAPQTHRASE----PPPPNSSSSVHP 1016
P++ + + P P R + PPPP S P
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
Score = 44.7 bits (104), Expect = 6e-04
Identities = 66/320 (20%), Positives = 107/320 (33%), Gaps = 50/320 (15%)
Query: 727 PPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGP---SV 783
PPP H +P R S+ A++ G++ + S +P +
Sbjct: 334 PPPRHRRSRSPVRR----RRRSS----ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Query: 784 QNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKE 843
+ S P R HR P TPPP + + ++ R V S +
Sbjct: 386 RRLSPSASPPRRRHRPSPP-ATPPPKTRHSPTPQQSNRTRKSR---VSVSPGRTSGKVTK 441
Query: 844 RESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKD 903
+ EKR S PSPAP L + A ++ + + ++ ++ S+S
Sbjct: 442 HKGTEKRES--PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS 499
Query: 904 LAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 963
++++ + K H+ +G GR + A PSP R + P R
Sbjct: 500 SSSEDERPKRSHVK----NGEVGRRRRHSPSRSAS-PSPRKRQ---KETSPRGRRRRSPS 551
Query: 964 P----RKGEPAYENPKKSSEVKVKEERKEDHDLPPEA---------------------PQ 998
P R+ P+ P + R+ PP P+
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611
Query: 999 THRASEPPPPNSSSSVHPGP 1018
AS PPPP +S P P
Sbjct: 612 RRTASPPPPPKRRASPSPPP 631
Score = 38.5 bits (88), Expect = 0.041
Identities = 51/234 (21%), Positives = 86/234 (36%), Gaps = 27/234 (11%)
Query: 798 RTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSP 857
R+PP P P + R + +A+ R R ++ + + ++ + + S
Sbjct: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR 427
Query: 858 APVLPVNALGHTRSSTEQIRAHLNTEAREKDKP--KERERDHSESRKD-----LAADE-H 909
V P G ++ H TE RE P K R+ + SES +D AAD
Sbjct: 428 VSVSPGRTSG-------KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
Query: 910 KAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEP 969
+ ++ + G ++ E ++ R +V+ V R +S S R A P
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKR---SHVKNGEVGRRRRHSPS-RSASP----- 531
Query: 970 AYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMP 1023
+P+K + R+ PP + S PPP + P P P
Sbjct: 532 ---SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTP 582
Score = 33.9 bits (76), Expect = 1.0
Identities = 58/285 (20%), Positives = 91/285 (31%), Gaps = 34/285 (11%)
Query: 768 SVTPNSMFGHKD-GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDR 826
S +P+ K+ P + +P P R R+P P P P R + + R
Sbjct: 528 SASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587
Query: 827 DRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 886
R R S +++R+S PSP P + T A
Sbjct: 588 RRSPSPRRYS--------PPIQRRYS--PSPPP----------KRRTASPPPPPKRRASP 627
Query: 887 KDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQ----LARVPSP 942
PK R HS K ++ K + L K G + EA+ PSP
Sbjct: 628 SPPPKRRV-SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP 686
Query: 943 YVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHR- 1001
R P S+ P + P++ + + + V E K+ +PQ+ R
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 1002 -------ASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISS 1039
+ P P P P+ S + + P+ S
Sbjct: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 64.7 bits (156), Expect = 5e-10
Identities = 69/235 (29%), Positives = 91/235 (38%), Gaps = 44/235 (18%)
Query: 256 LPEHDSQDAGPIVP---KISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTE 312
LP + AG P K S + R Q SQ + K P P V Q +
Sbjct: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQH-------SGALFKPPTPPVMQ---SQSVK 698
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAP----QPQVQRPPRPQSPT 368
PQ+ P P+ V PP PPP G AQL+PAP PQ PP P
Sbjct: 699 PQILVP---PNGVVPPPPPPPPPPTP-----GSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750
Query: 369 QLLH--QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
Q+ H Q PP P P A +++ + +S+++ P TQ APP
Sbjct: 751 QVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP------ 804
Query: 427 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPT--------ALPPPPPLT 473
+P P +P +F + PP+ P PPT A PPP PL+
Sbjct: 805 --TPTP-PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Score = 61.2 bits (147), Expect = 6e-09
Identities = 58/224 (25%), Positives = 83/224 (37%), Gaps = 32/224 (14%)
Query: 286 KEPIFEPVVLKDPCPQVAQPIPQPQ--------TEPQLRAPSPDPDLVQRTEA----PPQ 333
K+P F + P P+P P +P SP P +V++ + PP
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT 874
Query: 334 PPPLSTQP---------PQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNL----PPVQA 380
PP + +QP PQ PP + +P QP P P P +L PP
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 381 HPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA--KTQPAPPHISHHPSASPFPLSLPNH 438
P+ P ++ +S++S+P K P P S S+S P
Sbjct: 935 VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994
Query: 439 SPLHSFTPTLQPPAHSHHPNM-FAPPTALPPPPPLTSGSLQVAG 481
+ S PPA S P+ PP A PP P G L ++G
Sbjct: 995 PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP----GKLNLSG 1034
Score = 60.5 bits (145), Expect = 1e-08
Identities = 131/548 (23%), Positives = 167/548 (30%), Gaps = 104/548 (18%)
Query: 274 LERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQ 333
LE S + + P V P P++ P Q P L P P P PP
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP--------PPP 638
Query: 334 PPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSA 393
PPP PP PP Q AP P + T QN H A
Sbjct: 639 PPP----PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN---ASQHSGALFKPPTPPV 691
Query: 394 YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH 453
S S+ L P P PP A P P S P PP
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP---PPLK 748
Query: 454 SH---HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADR 510
H H APPT PPPPP+ + L Q+ +
Sbjct: 749 IHQVQHITQVAPPTP-PPPPPIPAP---------------------------LPPQAPPK 780
Query: 511 GASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTK 570
P P T T P + A PTP PP+ P K
Sbjct: 781 PLVTIPAP-------------------TSTKTVAP----VVTQAAPPTPTPPV---PPAK 814
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQ 630
P + S PP P+ PPT P Q +F K P ++ P V Q
Sbjct: 815 KQPAFPASYIPPSPPTPP--VPVPPPTLP---KQQSFCAKPP-PSPLSPVPSVVKQIASQ 868
Query: 631 KDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRP 690
P T P M +P K + ++A Q VK + + P + P+F P
Sbjct: 869 FPPPPTPP--AMESQPLK--PVPANVAPQ---SPPAVKAKPKWQPSSIPVP-SPDFPPPP 920
Query: 691 PGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTF 750
P SL P + P A PT G P ++ + +P P
Sbjct: 921 PESSLVFPPPPPSPVPAPPP--PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978
Query: 751 TGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWL 810
+ + + G PSV V F+ P E + T P PP
Sbjct: 979 SSIKSSSGAEHPEPKRPSV----------DSLVSKFTPPAESGSPSKETLPPPAAPP--- 1025
Query: 811 KPGELERS 818
KPG+L S
Sbjct: 1026 KPGKLNLS 1033
Score = 55.5 bits (132), Expect = 3e-07
Identities = 164/725 (22%), Positives = 225/725 (31%), Gaps = 139/725 (19%)
Query: 374 NLPPVQAHPSAQSLS-----QPLSAYNSSSLSLNSLSSS--------RSSTPAKTQPAPP 420
++P Q++ S QS S QP S S+ + S + SS P
Sbjct: 542 SIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRP 601
Query: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
+ S P SP P + ++ P PP P PP PPPPPL S S A
Sbjct: 602 YTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP----PPPPPPPPPPLPSQSAPSA 657
Query: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
G A I R L + S GA PP Q Q +
Sbjct: 658 GSAAPMFVKYSTITR-------LQNASQHSGALFKPP---TPPVMQSQSVKPQILVPPNG 707
Query: 541 HTFTPFPHAIPPT------AIMPTPAPPMFDKYPTKVDPFYRHSLFH----------SYP 584
P P PPT + P P P ++ P H + H P
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767
Query: 585 PAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARP--GTVPHTLLQKDPRLTDPF--- 639
P + +PP PP P ++ KT P+ A P T P +K P +
Sbjct: 768 PIPAPLPPQAPPK-PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 640 ----------RPMLRKPGKWCAMHVHIAWQ-IYHHQQKVKKQMQSDPHKLDFGLKPEFLS 688
P L K +CA + +++ Q P P S
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMES 880
Query: 689 RP--PGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNR 746
+P P P+ P A+P S+ P F PPP S+ + P P
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP---DFPPPPPESSLVFPPPPPSPVPA 937
Query: 747 PSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTP 806
P P P + P+ +P + ++ + P P
Sbjct: 938 PP------------------PPPPPTA------SPTPDKSGSPGKKTSK--TSSPGGKKP 971
Query: 807 PPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSP-APVLP--- 862
PP + +S+S A H + DS VSK ES + P P AP P
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKR-PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Query: 863 ----VNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPE 918
VN G + +A + R KD E S+S D E LP
Sbjct: 1031 NLSGVNLPGVLQQGCVSAKAPV-LSGRGKDSVVEFPSPPSDS--DFPP---PPPETELP- 1083
Query: 919 KDGHGHEGRAAGEEAKQLARVPSPYV----RTPVVESARPNSTSSREAEPRKGEPAYENP 974
L + P V +P V P + +K P
Sbjct: 1084 -----------------LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPK 1126
Query: 975 KKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPM 1034
+ S + E E + PQ P P SS SV PG LA + T+ I
Sbjct: 1127 RNDSTRLTQAEISEQPTMATVVPQV-----PTSPKSSLSVQPGFLADLNRTLQRKSITRH 1181
Query: 1035 NSISS 1039
S+SS
Sbjct: 1182 GSLSS 1186
Score = 42.0 bits (97), Expect = 0.004
Identities = 58/261 (22%), Positives = 90/261 (34%), Gaps = 56/261 (21%)
Query: 255 TLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQ 314
T P +SQ P+ ++ K++ P ++P + P P P P E
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAK-----PKWQPSSIPVPSPD----FPPPPPESS 924
Query: 315 LRAPSPDPDLVQRTEAPPQPPPLSTQPP---QGPPEAQLQPAPQPQVQRPP--------- 362
L P P P V APP PPP + P G P + P ++PP
Sbjct: 925 LVFPPPPPSPVP---APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981
Query: 363 ---------RPQSPT--QLLHQNLPPVQA-HPSAQSLSQPLSAYNSSSLSLNSLS----- 405
P+ P+ L+ + PP ++ PS ++L P + L+L+ ++
Sbjct: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 406 ------------SSRSSTPAKTQPAPPHISHHPSASP-FPLSLPNHSPLHSFTPTLQPPA 452
S R P+PP S P P L LP F+ P
Sbjct: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101
Query: 453 H--SHHPNMFAPPTALPPPPP 471
+ P ++ + PPP
Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPP 1122
Score = 37.0 bits (84), Expect = 0.12
Identities = 49/208 (23%), Positives = 79/208 (37%), Gaps = 17/208 (8%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQL-RAPSPDPDLVQRTEAPPQPPP--LSTQPPQGPPEA 348
P VL+ C P+ + + + PSP D ++ PP PP L P + P
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSD----SDFPPPPPETELPLPPIEIPAVF 1093
Query: 349 QLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSR 408
+P+ V P +PQ +++ + PP P ++ A S ++ ++
Sbjct: 1094 SGNTSPKVAVVNP-QPQQWSKMSVKKAPP-PTRPKRNDSTRLTQAEISEQPTMATVVPQV 1151
Query: 409 SSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPP 468
++P + P + + S+ H L S +P A ALPP
Sbjct: 1152 PTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD-------MALPP 1204
Query: 469 PPPLTSGSLQVAGHPAGSTYSEQDILRQ 496
PPP Q AG+ GS S LR+
Sbjct: 1205 PPPELLSDQQKAGY-GGSHISGYATLRR 1231
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 63.9 bits (154), Expect = 9e-10
Identities = 79/346 (22%), Positives = 127/346 (36%), Gaps = 38/346 (10%)
Query: 104 KDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLG 163
K +L + + TP KKK++ G S R SS ++ R+ +
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK--SSKKKKHRSESESKK 226
Query: 164 KRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDS 223
++ + P + K + S S + + +S+ HRS+S +DS+ S
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS----ADSA------------S 270
Query: 224 DSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS-- 281
SD S +++ K T + + P G E D+ + P G +Q S
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP------GTTSTQRPSSP 324
Query: 282 QDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQP 341
+ K+P P KD + + E PSP P+ PP P PL +
Sbjct: 325 ETATKQPS-SPYEDKD----------KDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
Query: 342 PQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL 401
G P+ + PP SPT+ P + S+ S S P S + +S
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP-QPTKVSR 432
Query: 402 NSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPT 447
++ SS S PA + IS P++ HS TP+
Sbjct: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478
Score = 55.8 bits (133), Expect = 2e-07
Identities = 117/520 (22%), Positives = 185/520 (35%), Gaps = 88/520 (16%)
Query: 6 RGHGLRKKRRSRS-QRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKE------- 57
R +++ RSRS QR RSR G + GR+ + S A+ S
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 58 DNGKPPSSAPSRPRPP-RRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEK 116
+ P+ SR R P RR+ R T A + + P R +
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRG-----------------RSRSRTPARRRSR 626
Query: 117 RQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLK 176
++P+ ++ R + + S +SR P R R + R + P
Sbjct: 627 TRSPVRRRSR---SRSPARRSGRSRSRTPAR--RGRSRSRTPARRGRSRSRTPARRSGRS 681
Query: 177 PGQNSCRDSDSESAS---GESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASD 233
+ R S S + G S+ RS R S S P G S S E K
Sbjct: 682 RSRTPARRGRSRSRTPRRGRSRS--RSLVRRGRSHSRTPQRRGR-----SGSSSERKNKS 734
Query: 234 ASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPV 293
+S++ + N PE+ + S+ RS+ KS+ + +
Sbjct: 735 RTSQRRSRS---NSSPEMKKSRISSRRSRSLSS--------PRSKAKSRLSLRRSLSG-- 781
Query: 294 VLKDPCPQVAQPIPQPQT---EPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQL 350
PCP+ P ++ Q +A S P R+ + P PP ++ P +
Sbjct: 782 --SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSRQSHSSS 838
Query: 351 QPAPQPQVQRPPRPQSPT--QLLHQNLPP-----VQAHPSAQSLSQPLSAYNSSSLSLNS 403
P P+ + PPR S T Q Q++ P ++ P + S+ S ++ S S
Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
Query: 404 LSS--------SRSSTP---AKTQPAPPHISHHPSASPFPLSLPNH---------SPLHS 443
+ S SRSS+P K +P SH S+SP P + + SP +
Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 444 FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
L P +SH + P PP S S ++ +P
Sbjct: 959 VESRLL-PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 55.5 bits (132), Expect = 3e-07
Identities = 110/477 (23%), Positives = 164/477 (34%), Gaps = 63/477 (13%)
Query: 13 KRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAP----- 67
+RRSRS+ R R A G RT A S S + +G+ S P
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR 691
Query: 68 SRPRPPRRKRRESTS--------AEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQT 119
SR R PRR R S S + G + +S + K+ + Q R +
Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS-----SERKNKSRTSQRRSRSNSS 746
Query: 120 PLTKKKREALTNGLSFHSK----KSRLSHPHHYSSDRENDRNLCQHLGKRKK----MPKA 171
P KK R + S S KSRLS S + Q +R + PKA
Sbjct: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806
Query: 172 LRQLKP--GQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEE 229
+ P ++S + + S+ H SSS S P G+ + E
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS----ITSPQANE 862
Query: 230 KASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPI 289
++ F + + DPEL T H + P K S R Q S+ +P
Sbjct: 863 QSVTPQRRSCFES---SPDPELKSRTPSRHSCSGSSPPRVKSSTPPR-QSPSRSSSPQPK 918
Query: 290 FEPVVLKDPCPQVAQPIPQPQ------TEPQLRAPSP------------------DPDLV 325
+ ++ P P T + R+ SP PD
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978
Query: 326 QRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQ-LLHQNLP-PVQAHPS 383
+ E PP+ + P +AQ P P + P PQ ++ L Q+ P +
Sbjct: 979 VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
Query: 384 AQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSP 440
+S + P +Y S SL S++S ++ + P + S SP S SP
Sbjct: 1039 VKSSTPPGESYFGVS-SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSP 1094
Score = 45.4 bits (106), Expect = 3e-04
Identities = 67/280 (23%), Positives = 103/280 (36%), Gaps = 45/280 (16%)
Query: 789 PHEPWNRLHRTPPS-FPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV 847
P +P++ + + S PTP K + +R + + R+ K+ S K E ES
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE-RKKSSKKKKHRSESESK 225
Query: 848 EKRHSSHPSPAPVLPVNALGHTRS-----STEQIRAHLNTEAREKDKPKERERDHSESRK 902
+++H P+P RS + + RAH +T A D + S SR
Sbjct: 226 KRKH-RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA---DSASSSDTSRSRSRS 281
Query: 903 DLAADEHKAKEGHLPE-KDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSRE 961
A A G P G EG A E P +TS++
Sbjct: 282 AAAKTHTTALAGRSPSPASGRRGEGDAPFSE---------------------PGTTSTQ- 319
Query: 962 AEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQ-THRASEPPPPN----SSSSVHP 1016
P E A + P E K K+++++ P +P+ + EPP P P
Sbjct: 320 -RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
Query: 1017 GPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLP 1056
PLA+ P++ P+N S TR +P LP
Sbjct: 379 QPLATTPLSQ-----EPVNPPSEASPTRDRSPPKSPEKLP 413
Score = 45.1 bits (105), Expect = 4e-04
Identities = 99/466 (21%), Positives = 152/466 (32%), Gaps = 63/466 (13%)
Query: 24 RRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSA 83
RRSR G A RT SSS + K PS P K + T
Sbjct: 795 RRSRSGSSQPKA----KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850
Query: 84 EEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLS 143
+ S + +A E+ V + + E P K + + + + + S
Sbjct: 851 RQG--------SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS 902
Query: 144 HPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR 203
P S R + PK + P Q S S S S S + SR
Sbjct: 903 TPPRQSPSRSSS-----------PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR 951
Query: 204 ERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQD 263
S+ S L Y S + K + + ++ ++ P++ T P
Sbjct: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG----- 1006
Query: 264 AGPIVPKISGLERS--QEKSQDCCKEPIFEPVVLKDPCPQVAQPIP-------------- 307
P +SG + QEKS+D + + L C V P
Sbjct: 1007 -----PSLSGSKSPCPQEKSKDSLVQSCPGSLSL---CAGVKSSTPPGESYFGVSSLQLK 1058
Query: 308 -QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQ- 365
Q QT P R+ + P++ Q P S P+G P + + P R
Sbjct: 1059 GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDR 1118
Query: 366 ---SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHI 422
S + +L + P Q+ + S S P + ++S L + L ++ S P
Sbjct: 1119 GEFSASPMLKSGMSPEQSRFQSDSSSYP-TVDSNSLLGQSRLETAESKEKMALPPQEDAT 1177
Query: 423 SHHP----SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPT 464
+ P SPFP+ S L F TL+ P +P T
Sbjct: 1178 ASPPRQKDKFSPFPVQDRPESSL-VFKDTLRTPPRERSGAGSSPET 1222
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/354 (20%), Positives = 116/354 (32%), Gaps = 48/354 (13%)
Query: 20 RDRERRSRGGLGAGAAGGGGAGRTRALSLAS----------SSGSDKEDNGKPPSSAPSR 69
R RRSR G G G G +LS +S S G + D+ P + P
Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
Query: 70 PRPPRRK-------------RRESTSAEEDIIDGFAMTSFV-------TFEALEKDVALK 109
PRP R +RE + +E + + + + + L+ +
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
Query: 110 PQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMP 169
PQER E +P +K K S + S R + + K + P
Sbjct: 1553 PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612
Query: 170 KALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEE 229
+A S DS E + + R S S PS G+ ++S E
Sbjct: 1613 RA--------QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS---STESSPEH 1661
Query: 230 KASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPI 289
++ + + + +P+ T P S + P + + + L R + +S E
Sbjct: 1662 PPKSRTARRGSRS---SPEPKTKSRTPPRRRSSRSSPELTRKARLSR-RSRSASSSPETR 1717
Query: 290 FEPVVLKDPCPQVAQPIPQPQTEPQLR---APSPDPDLVQRTEAPPQPPPLSTQ 340
P V+ P P ++ R A SP R P P P Q
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
Score = 39.7 bits (91), Expect = 0.018
Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 352 PAPQPQVQ--RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
PAP+ V+ RPP P + + + S+ S S S+ +SSS S +S SSS S
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 410 STPAKTQPAPPHISHHPSASPFPLS 434
S+ + PA P P A P P S
Sbjct: 2644 SSSSSPSPAKP----GPQALPKPAS 2664
Score = 38.9 bits (89), Expect = 0.031
Identities = 75/341 (21%), Positives = 116/341 (34%), Gaps = 52/341 (15%)
Query: 268 VPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQR 327
VP+ ERS S +KD P+ + + P LR S P
Sbjct: 1410 VPRTPSRERSSSASSP----------EMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSL 1459
Query: 328 TEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRP-PRPQSPT--QLLHQNLPPVQAHPSA 384
+ + P + P +G E P P+ Q P PR +SP+ +L ++ L P + +
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519
Query: 385 QS-------------------LSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP-------- 417
+S SQ L S+S S S S + AKT+
Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579
Query: 418 -APPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS---HHPNMFAP-PTALPPPPPL 472
+ P + SP S SP P P A S P AP P ALP
Sbjct: 1580 GSSPEVDSKSRLSP-RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638
Query: 473 TSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQ 532
S S P GS+ +E S++A RG+ P P ++ + +
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPP------KSRTARRGSRSSPEPKTKSRTPPRRRSSR 1692
Query: 533 HTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDP 573
+ + T + + + + + PP + P+ P
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP 1733
Score = 38.1 bits (87), Expect = 0.053
Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 13/199 (6%)
Query: 348 AQLQPAPQPQVQRPPRPQ-SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSS 406
+ L P+ ++R P P +P + + + PP + S S+ +SSS S +S SS
Sbjct: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 407 SRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTAL 466
S SS+ + + + S S+SP P + +P PP + P +L
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
Query: 467 PPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQ 526
L+ + E+ + + R S S++RG+ G R+ H+
Sbjct: 2686 RDSRSLSYSPV------------ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733
Query: 527 HQHQHQHTHQHTHQHTFTP 545
+ + H+ + +P
Sbjct: 2734 RRRETPSPRPMRHRSSRSP 2752
Score = 37.4 bits (85), Expect = 0.091
Identities = 56/266 (21%), Positives = 83/266 (31%), Gaps = 31/266 (11%)
Query: 167 KMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSD 226
+ P AL L+P + S S S+S S SSS S SS+ S G+ +
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575
Query: 227 QEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCK 286
+ S + K V + PE S + S S S
Sbjct: 2576 LKRVPSPTPAPK--EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 287 EPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQG 344
+ P PQ P+ +P P +R+ +P +P ++
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 345 PPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P + +P+PQP PR Q Q S+ S
Sbjct: 2694 SPVERRRPSPQPS----PRDQ-----------------------QSSSSERGSRRGQRGD 2726
Query: 405 SSSRSSTPAKTQPAPPHISHHPSASP 430
S S S + P+P + H S SP
Sbjct: 2727 SRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 36.2 bits (82), Expect = 0.20
Identities = 50/205 (24%), Positives = 76/205 (37%), Gaps = 33/205 (16%)
Query: 14 RRSRSQ-----RDRERRS-RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---- 63
RRSRS +D+ R + R G+ ++ A RAL S SGS + G P
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 64 --SSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP- 120
S+P P R RR S S+ E K + P R R +P
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPE-----------------PKTKSRTPPRRRSSRSSPE 1696
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LT+K R + + + S ++R P + R + ++ + + R +
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRH---RRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Query: 181 SCRDSDSESASGESKGFHRSSSRER 205
S S + +G RS SR R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSR 1778
Score = 34.7 bits (78), Expect = 0.59
Identities = 38/213 (17%), Positives = 78/213 (36%), Gaps = 11/213 (5%)
Query: 817 RSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRS---ST 873
RS R +R S S +++ +S + S + +P + + + RS S+
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764
Query: 874 EQIRAHLNTEAREK---DKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 930
+ +A R P +++ + R+ + + P +
Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK 824
Query: 931 EEAKQLARVP----SPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSS-EVKVKEE 985
+++K +R SP+ + R S +S +A + P + +SS + ++K
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR 884
Query: 986 RKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGP 1018
H +P ++S PP + S S P P
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
Score = 33.5 bits (75), Expect = 1.3
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 44/235 (18%)
Query: 798 RTPP----SFPTPPPWLK---PGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV--E 848
RTPP S +PPP K P S+S+ R S++ +SV +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
Query: 849 KRHSSHPSPAPVLPVNALG-HTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAAD 907
+R SP P L H+ S + R +T R+ S SR ++
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ-----------SPSRS--SSP 915
Query: 908 EHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKG 967
+ K K P + H G ++ PSP T R S S +
Sbjct: 916 QPKVKAIISPRQ--RSHSGSSS----------PSPSRVTSRTTPRRSRSVSPCSNVESRL 963
Query: 968 EPAYENPKKSS-EVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLAS 1021
P Y + SS + KVK E PP Q+H S P P + PGP S
Sbjct: 964 LPRYSHSGSSSPDTKVKPET------PPR--QSHSGSISPYPKVKAQTPPGPSLS 1010
Score = 33.1 bits (74), Expect = 1.7
Identities = 54/263 (20%), Positives = 86/263 (32%), Gaps = 24/263 (9%)
Query: 756 VGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSF-----PTPPPWL 810
V G+ G + T +S H SV PH PP+ P+ L
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE----PPASTGAQQPSALAAL 2524
Query: 811 KPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTR 870
+P + RS+S+++ SS S S + SS PV P AL
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS----LPVQPEVALKRVP 2580
Query: 871 SSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 930
S T + + + P +R+R S S ++ + ++
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKR-RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 931 EEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDH 990
+ + PSP P A P S ++ P GE +P+K + ++
Sbjct: 2640 SSSSSSSSSPSPAKPGP---QALPKPASPKKPPP--GERRSRSPRKPI-----DSLRDSR 2689
Query: 991 DLPPEAPQTHRASEPPPPNSSSS 1013
L + R S P P S
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQS 2712
Score = 32.3 bits (72), Expect = 2.9
Identities = 29/111 (26%), Positives = 40/111 (36%), Gaps = 14/111 (12%)
Query: 920 DGHGHEGRAAGEEAKQLA-RVPSPY--------VRTPVVESARPNSTSSREAEPRKGEPA 970
DG + + EAKQ A P PY R+P + + R P
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 971 YENPKKSSEVKVK---EERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGP 1018
E K S + K + E +K H P P++ R S+ S S P P
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSP--TPKSKRKSKDKKRKRSRSTTPAP 255
Score = 32.3 bits (72), Expect = 2.9
Identities = 54/254 (21%), Positives = 87/254 (34%), Gaps = 40/254 (15%)
Query: 777 HKDGPSVQNFSNPHEPWNRLHRTPPSFP----------TPPPWLKPGELERSASAAAHDR 826
H+ PSV + + + R S P +P P KP L+RS S + ++
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP--KPRGLQRSRSRSRREK 1781
Query: 827 DRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALG---HTRSSTEQIRAHLNTE 883
R +RD S S +S +R S + V G H+RS Q + ++
Sbjct: 1782 TRTTRRRDRSGSS-----QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 884 AREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPY 943
R + R R SRK +++ P K A ++
Sbjct: 1837 RR-----RGRSRTPPTSRK-----RSRSRTSPAPWKRSRSRASPATHRRSRS-------- 1878
Query: 944 VRTPVVESARPNSTSSREAEPR-KGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRA 1002
RTP++ R S +S + R + + + S R+ PP + R+
Sbjct: 1879 -RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937
Query: 1003 SEPPPPNSSSSVHP 1016
P S S P
Sbjct: 1938 RTPTTRRRSRSRTP 1951
Score = 31.2 bits (69), Expect = 6.5
Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 11 RKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLAS------------SSGSDKED 58
RK+ RS + + RR+ A +A R+R+ S A+ S S +
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 59 NGKPPSSAP-----SRPRPPRRKRRESTSAEED 86
G P S P RP P ++ +S ED
Sbjct: 305 EGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Score = 31.2 bits (69), Expect = 6.5
Identities = 60/303 (19%), Positives = 97/303 (32%), Gaps = 42/303 (13%)
Query: 719 HPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHK 778
H + +P P P + P +H E + P T G A + S TP+ G
Sbjct: 433 HASSSPESPKPAPA----PGSHREISSSP---TSKNRSHGRAKRDKSH-SHTPSRRMGRS 484
Query: 779 DGPSV--QNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELER---SASAAAHDRDRDVDKR 833
P+ + S P R H S P W + +R S S R R +
Sbjct: 485 RSPATAKRGRSRSRTPTKRGHSRSRS----PQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Query: 834 DSSVSKDDKER---ESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKP 890
S S++ + R S + S SPA +R+ + R+ T AR + +
Sbjct: 541 GWSRSRNTQRRGRSRSARRGRSHSRSPA----TRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 891 KERERDHSESRKDLAADEHKAK-----------------EGHLPEKDGHGHEGRAAGEEA 933
+ R S SR +++ P + R
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 934 KQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKS-SEVKVKEERKEDHDL 992
+ +R P+ R+ AR + S R+G P++ S + R H
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 993 PPE 995
P+
Sbjct: 717 TPQ 719
Score = 30.8 bits (68), Expect = 8.5
Identities = 49/235 (20%), Positives = 79/235 (33%), Gaps = 16/235 (6%)
Query: 798 RTPP---SFPTPPPWLKPGELER---SASAAAHDRDRDVDK--RDSSVSKDDKERESVEK 849
RTPP S + P + L R SAS++ R R + R SVS + +S
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742
Query: 850 RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEH 909
R S + G + S + + +R + R RD S S + +
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802
Query: 910 KAKEGH---LPEKDGHGHEGR--AAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEP 964
+++ + G G+ R A E ++ +R RTP R S +S
Sbjct: 1803 RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWK 1862
Query: 965 R---KGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHP 1016
R + PA +S + R P ++ + S S P
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917
Score = 30.8 bits (68), Expect = 8.5
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 354 PQPQVQRPPRP---QSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P V PP Q P+ L L P + S+ S S S+ +SSS S +S SSS SS
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAA--LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Query: 411 TP---AKTQPAPPHIS--HHPSASPFP 432
+ + P P ++ PS +P P
Sbjct: 2560 SSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Score = 30.8 bits (68), Expect = 8.5
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 3/80 (3%)
Query: 11 RKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSA---P 67
RK+R S S S + ++ + + + S +SSS S KP A P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 68 SRPRPPRRKRRESTSAEEDI 87
+ P+ P R S S + I
Sbjct: 2663 ASPKKPPPGERRSRSPRKPI 2682
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 63.5 bits (153), Expect = 1e-09
Identities = 87/332 (26%), Positives = 117/332 (35%), Gaps = 57/332 (17%)
Query: 300 PQVAQP--IPQPQTEPQLRAPSPDPDLVQRTEAP---PQPPPLSTQPPQGPPEAQLQP-- 352
PQ +P PQP+ EP L A +P L + E P PQP L P P P
Sbjct: 763 PQAEEPHLSPQPE-EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 353 ---APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
+PQP+ + PQS L P ++H S + PLS +
Sbjct: 822 PCLSPQPE-ESHLSPQSEEPCLSPR--PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
Query: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNM---FAPPTAL 466
P P P +S P LS P PL S P P + S P++ PP L
Sbjct: 879 ELPLFPPPGEPSLS--PLLGEPALSEPGEPPL-SPLPEELPLSPSGEPSLSPQLMPPDPL 935
Query: 467 PPP-PPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFH 525
PPP P+ + + A P G EL F A +D + L P L T
Sbjct: 936 PPPLSPIITAAAPPALSPLG-----------ELEYPFGAKGDSDPESPLAAP-ILETPIS 983
Query: 526 QHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPP-------MFDKYPTKVDPFYRHS 578
+ P +PP + P+P P + + P + P +HS
Sbjct: 984 PPPEAN------------CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031
Query: 579 LFHSYPPAVSGIPPMIP-----PTGPFGSLQG 605
L P PP +P P P G + G
Sbjct: 1032 LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063
Score = 60.8 bits (146), Expect = 8e-09
Identities = 108/440 (24%), Positives = 137/440 (31%), Gaps = 83/440 (18%)
Query: 310 QTEPQLRAP-SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT 368
Q EPQL AP + + L+ E P PP P PPEA P ++ P P++
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA-- 482
Query: 369 QLLHQNLP----PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISH 424
LH + P P+ P LS P + S L + LS S P+ P +S
Sbjct: 483 --LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP--LSP 538
Query: 425 HPSASPF--PLSLPNHSPLHSFTPTLQPPAHSH------HPNMFAPPTALP-PPPPLTSG 475
P ASP P SP PT PP S M PP P PPP S
Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598
Query: 476 SLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTH 535
S E+ L L+ D + + PPP +
Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPED--SPMSPPP-----------EESPMS 645
Query: 536 QHTHQHTFTPFP---HAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPP 592
+P P PP P PP ++ PT S PP S + P
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPP--EESPT------------SPPPEASRLSP 691
Query: 593 MIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAM 652
PP P + P D A P P L P P P+ +P + C
Sbjct: 692 --PPED---------SPTSPPPEDSPASPP--PEDSLMSLPLEESPLLPLPEEP-QLCPR 737
Query: 653 HVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLF 712
PH +P RP P L PH +P
Sbjct: 738 -------------------SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC 778
Query: 713 SAAGAAHPTGTPFGPPPHHS 732
A P +P PH S
Sbjct: 779 LCAVPEEPHLSPQAEGPHLS 798
Score = 57.8 bits (138), Expect = 7e-08
Identities = 190/890 (21%), Positives = 278/890 (31%), Gaps = 206/890 (23%)
Query: 278 QEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP--QPP 335
Q K D ++ + L+ P A P P P + SP T A +PP
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRP---PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392
S P P E L+ PQ Q P P +P L P A P+ P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP--TAPPTYPPYPSPTG 2204
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFT------- 445
A + L + S + P + PP H ++P P P L +
Sbjct: 2205 APAQPPM-LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 446 -------PTLQPPAHSH--------HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSE 490
P L PP + A + PP S H G
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 491 QDILRQELNTRFLASQSADRGASLG-----PPPYLRTEFHQHQHQHQHTHQHTHQHTFTP 545
D+ + L R ASQ + LG PPP Q +H F P
Sbjct: 2324 PDVFKAPLTPR--ASQVEPQSPGLGLRPQEPPP----------AQALAPSPPSHPDIFRP 2371
Query: 546 ----FPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFG 601
P+A PP P P P P + +PP P+ PF
Sbjct: 2372 GSYTDPYAQPPLTPRPQPPP----------------------PESCCALPPRSLPSDPFS 2409
Query: 602 SLQGAFQPKTSNPIDVAARPGTV----------------PHTLLQKDPRLTDPFRPMLRK 645
+ + Q ++S+ + RP + P++ P+ DPF P+ +
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469
Query: 646 PGKWCAMHVHIAWQIYHHQQKVKKQMQSDP--------HKLDFGLKPEFLSRPPGPSLFG 697
P A + H + P K+ G P F+ R PG F
Sbjct: 2470 PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV-RSPGTGAFV 2528
Query: 698 AIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEP---FNRPSTFTGLA 754
P P + P P PPPH N +H P +P +
Sbjct: 2529 GTPSPMRFTFPQAV-GEPSLKPPVPQPGLPPPHGIN-----SHFGPGPTLGKPQSTNYTV 2582
Query: 755 AVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFS-NPHEPWNRLHRTPPSFPTPPPWLKPG 813
A G F G+P G G + +++ +P P + L PP+ P+L G
Sbjct: 2583 ATGN--FHPSGSP-------LGPSSGSTGESYGLSPLRPPSVL--PPPAPDGSLPYLSHG 2631
Query: 814 ELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSST 873
+RS + V+KR+ + + E + P ++ L T
Sbjct: 2632 ASQRSGITS------PVEKREDPGTGMGSSLATAELPGTQDPG------MSGLSQTELEK 2679
Query: 874 EQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEA 933
++ R L RE ++ +R+ K+ AA A G + G E + E
Sbjct: 2680 QRQRQRL----RELLIRQQIQRNTLRQEKETAA----AAAGAVGPPGSWGAEPSSPAFE- 2730
Query: 934 KQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLP 993
QL+R +P+ T KSS V + + L
Sbjct: 2731 -QLSRGQTPFAGT---------------------------QDKSSLVGLPPSKLSGPILG 2762
Query: 994 PEA-PQTHRASEPPPPNSSSSV-------------------HPGPL-------------- 1019
P + P R S PPPP + SS+ +PG L
Sbjct: 2763 PGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQ 2822
Query: 1020 --ASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISP-LPG-GERFPYPS 1065
A+ M ++ P L R + +P GIS LPG GE P P+
Sbjct: 2823 ATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPA 2872
Score = 53.1 bits (126), Expect = 2e-06
Identities = 54/200 (27%), Positives = 75/200 (37%), Gaps = 27/200 (13%)
Query: 295 LKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPP-----QGPPEAQ 349
L + P + P P + P +P+ P R PP+ P S P + E+
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 350 LQPAPQPQVQRPPRPQSPTQLLHQN-LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSR 408
L P P+ PP SP L ++ L P + P + +L PLS +S S
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP 553
Query: 409 SSTPAKTQPAPP-----HISHHPSASPF-------PLSLPNHS----PLHSFTPTLQPPA 452
S P + P P +S P SP P+S P + P +P PP
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
Query: 453 HSHHPNMFAPPTA--LPPPP 470
S + PP A L PPP
Sbjct: 614 ES---PLSPPPEASRLSPPP 630
Score = 53.1 bits (126), Expect = 2e-06
Identities = 100/375 (26%), Positives = 132/375 (35%), Gaps = 52/375 (13%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA-QLQPAPQP 356
P P+ + P P+ P P E+P PPP P PPEA +L P P+
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP-EESPLSPPPEASRLSPPPED 632
Query: 357 QVQRPP---RPQSPTQLLHQNLP-PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP 412
PP P SP + + P PV + S PLS S + +SR S P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 413 AKTQPAPPHISHHPSASPFP----LSLP-NHSPLHSF--TPTLQPPAHSHHPNMFAPPTA 465
+ P P P ASP P +SLP SPL P L P + H +
Sbjct: 693 PEDSPTSPPPEDSP-ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751
Query: 466 LPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFH 525
L P P S Q A P S E+ L L+ Q+ G L P P E H
Sbjct: 752 LSPRPEEPHLSPQ-AEEPHLSPQPEEPCLCAVPEEPHLSPQA--EGPHLSPQP---EELH 805
Query: 526 -QHQHQHQHTHQHTHQHTFTPFP---HAIPPT---AIMPTP----APPMFDKYPTKVDPF 574
Q + H + +P P H P + + P P P +K P P
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP- 864
Query: 575 YRHSLFHSYPPAVSG-IP-----PMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTL 628
PP G P P+ PP G + + P P + PG P +
Sbjct: 865 -------EKPPEEPGQCPAPEELPLFPPPG-----EPSLSPLLGEP--ALSEPGEPPLSP 910
Query: 629 LQKDPRLTDPFRPML 643
L ++ L+ P L
Sbjct: 911 LPEELPLSPSGEPSL 925
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/188 (30%), Positives = 72/188 (38%), Gaps = 25/188 (13%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPP--LSTQPPQGPPEAQLQPAPQPQ 357
P+ + P P +T P P P E+P PPP L T PP P ++L P P+
Sbjct: 523 PEESPPSPALET-PLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASRLSPPPEES 579
Query: 358 VQRPP---RPQSPTQLLHQNLPPVQAHP-SAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
PP P SP + PP + P S PLS +S S S P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639
Query: 414 KTQP--APPHISHHPSASPFPL-----SLPNHSPLH---SFTPTLQPPAHSHHPNMFAPP 463
+ P PP +S SP P+ P SPL +PT PP S + PP
Sbjct: 640 EESPMSPPPEVSR---LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS---RLSPPP 693
Query: 464 TALPPPPP 471
P PP
Sbjct: 694 EDSPTSPP 701
Score = 50.8 bits (120), Expect = 8e-06
Identities = 95/417 (22%), Positives = 137/417 (32%), Gaps = 52/417 (12%)
Query: 257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEP--VVLKDPCPQVAQPIPQPQTEPQ 314
PE P ++S S + P+ P V P P V++ P P+ P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 315 LRAP-----SPDPDLVQRTEAP---PQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
P SP P+ + + P P PP P PPE L P + P P+
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 367 PTQLLHQNLPPVQAHPSAQSLS-QPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS-- 423
P P + P LS +P + S LS P PH+S
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 424 -HHPSASPFPLSL--------PNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTS 474
P SP P L P+ SP+ P L P H + + L P P +
Sbjct: 792 AEGPHLSPQPEELHLSPQTEEPHLSPVPE-EPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 475 GSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHT 534
S ++ P R E A L PPP E +
Sbjct: 851 LSPELEKPPLSP--------RPEKPPEEPGQCPAPEELPLFPPP---GEPSLSPLLGEPA 899
Query: 535 HQHTHQHTFTPFPHAIP-----PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSG 589
+ +P P +P ++ P PP D P + P + + PPA+S
Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP--DPLPPPLSPI----ITAAAPPALS- 952
Query: 590 IPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKP 646
P+ PFG+ +G P++ + P + P DP +P PM+ P
Sbjct: 953 --PLGELEYPFGA-KGDSDPESPLAAPILETPISPPPEANCTDP---EPVPPMILPP 1003
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/221 (26%), Positives = 81/221 (36%), Gaps = 27/221 (12%)
Query: 266 PIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLV 325
P P L S+ + P E + P P+ + P +P P P L
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP-PSPAL- 532
Query: 326 QRTEAPPQPPPLST-------QPPQGPPEAQLQPAPQPQVQR--PPRPQSPTQLLHQNLP 376
E P PPP ++ + P PP +L +P P+ R PP +SP +
Sbjct: 533 ---ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE-S 588
Query: 377 PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP----HISHHPSASPF- 431
P+ P A L P + S LS S S P ++ +PP +S P SP
Sbjct: 589 PMSPPPEASRLFPP---FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
Query: 432 -PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P + SPL + PP S + PP P PP
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEES---PLSPPPEESPTSPP 683
Score = 48.5 bits (114), Expect = 4e-05
Identities = 94/378 (24%), Positives = 125/378 (33%), Gaps = 75/378 (19%)
Query: 298 PCPQVAQPIP----QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQP---PQGPPE--- 347
P P+ ++ P P + P +P P R PP+ P+S P P PP
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 348 --------AQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQAHPSAQSLSQPLSAYN 395
++L P P+ PP +SPT + + PP + S P S
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 396 SSSL-SLNSLSSSRSSTPAKTQPAP----PHIS---HHPSASPFPLSLPNHSPLHSFTPT 447
SL SL S P + Q P PH+S P SP P P+ SP + P
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEPHLSP-QAEEPH 769
Query: 448 LQP----------PAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQE 497
L P P H P P P L P S E+ L +
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS--PQTEEPHLSPVPEEPCLSPQ 827
Query: 498 LNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMP 557
L+ QS + L P P + H + +P P PP
Sbjct: 828 PEESHLSPQSEE--PCLSPRP-----------EESHLSPELEKPPLSPRPEK-PPEEPGQ 873
Query: 558 TPAPPMFDKYPTKVDPFYRHSLFHSYPPAVS--GIPPMIP-----PTGPFGSLQGAFQ-- 608
PAP +P +P L PA+S G PP+ P P P G + Q
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGE---PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 609 -----PKTSNPIDVAARP 621
P +PI AA P
Sbjct: 931 PPDPLPPPLSPIITAAAP 948
Score = 44.3 bits (103), Expect = 7e-04
Identities = 107/434 (24%), Positives = 144/434 (33%), Gaps = 100/434 (23%)
Query: 227 QEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCK 286
+ KA + E+L + P G L DS +G + GLE K+ D K
Sbjct: 2280 ESRKALEVKKEELGAS-----SPSYGPPNLGFVDSPSSGT---HLGGLEL---KTPDVFK 2328
Query: 287 EPI------FEP----VVLKDPCPQVAQPI-PQPQTEPQLRAPSPDPDLVQRTEAPPQPP 335
P+ EP + L+ P AQ + P P + P + P D P P
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD-------PYAQP 2381
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN 395
PL+ P+PQ PP P+S L ++LP S P S
Sbjct: 2382 PLT---------------PRPQ---PPPPESCCALPPRSLP-----------SDPFSRVP 2412
Query: 396 SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
+S S +S S + P + P SP P S P P + P A H
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP-----QSRDPFAPLH 2467
Query: 456 HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ------SAD 509
P PP L SL G PA EL+ + + Q S
Sbjct: 2468 KPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG----ELHAKVPSGQPPNFVRSPG 2523
Query: 510 RGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIM------PTPAPPM 563
GA +G P +R F Q + P P PP I PT P
Sbjct: 2524 TGAFVGTPSPMRFTFPQAVGEPSLKPP-------VPQPGLPPPHGINSHFGPGPTLGKPQ 2576
Query: 564 FDKYPTKVDPFY---------RHSLFHSYPPAVSGIPPMIPPTGPFGSL----QGAFQPK 610
Y F+ S SY + P ++PP P GSL GA Q
Sbjct: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRS 2636
Query: 611 -TSNPIDVAARPGT 623
++P++ PGT
Sbjct: 2637 GITSPVEKREDPGT 2650
Score = 43.5 bits (101), Expect = 0.001
Identities = 86/444 (19%), Positives = 148/444 (33%), Gaps = 72/444 (16%)
Query: 98 TFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRN 157
+ + L++ L+ Q++++++Q +++++ L ++ +L ++ +
Sbjct: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQL 3955
Query: 158 LCQHLGKRKKMPKALRQLKPGQ-NSCRDSDSESASGESK-GFHRSSSRERLSDSSAPSSL 215
Q ++++ + +Q + G N R S + + + L S+P +L
Sbjct: 3956 QQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015
Query: 216 GTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLE 275
G ++ A S + ++ L +GT PE + + G + P +SG
Sbjct: 4016 GPTLLLTGK--EQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG-- 4071
Query: 276 RSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQP---QTEPQLRAPSPDPDLV------- 325
SQ +P QP PQP Q +P LR P V
Sbjct: 4072 ----DSQLLLVQP---------------QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 326 ----------QRTEAPPQP-----PPLSTQPPQGPPEAQLQPAPQPQVQRP------PRP 364
+EA P P +S G L QP ++RP P+P
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP 4172
Query: 365 QSPTQLLH--QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS------------S 410
P +L Q LP V P+ L L + + L LS +
Sbjct: 4173 PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQ 4232
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH--SHHPNMFAPPTALPP 468
+ PP+ SP L L F P P PP P
Sbjct: 4233 QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP 4292
Query: 469 PPPLTSGSLQVAGHPAGSTYSEQD 492
P L++G + HP S Q+
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQE 4316
Score = 43.1 bits (100), Expect = 0.002
Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 30/191 (15%)
Query: 299 CPQVAQ-PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQ 357
CP + P+ P EP L +P L + P PPLS P + P +P+ PQ
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSE-----PGEPPLSPLPEELPLSPSGEPSLSPQ 928
Query: 358 VQRP-PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSS----LSLNSLSSSRSSTP 412
+ P P P + ++ PP A L P A S L+ L + S P
Sbjct: 929 LMPPDPLPPPLSPIITAAAPP--ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPP 986
Query: 413 ----AKTQPAPPHISHHPSASPF----PLSL----PNHSPL--HSFTPTLQPPAHSHHPN 458
+P PP I SP P+ + P SPL HS P PP+ P
Sbjct: 987 EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP- 1045
Query: 459 MFAPPTALPPP 469
A P ++P P
Sbjct: 1046 --ALPLSVPSP 1054
Score = 42.4 bits (98), Expect = 0.003
Identities = 55/191 (28%), Positives = 69/191 (36%), Gaps = 41/191 (21%)
Query: 287 EPIFEPVVLK-DPCPQVAQPIPQPQTEPQLRAPSPDPDLVQ----RTEAPPQPP---PLS 338
EP P ++ DP P PI P L SP +L + ++ P+ P P+
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYPFGAKGDSDPESPLAAPIL 978
Query: 339 TQPPQGPPEAQL-QPAPQPQVQRPPRPQSPT---------------------QLLHQNLP 376
P PPEA P P P + PP P SP L+ QN P
Sbjct: 979 ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Query: 377 PVQAHPSAQSLS--QPLSAYN-----SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSAS 429
P Q P A LS PLS S L+ + + + S P P S PS
Sbjct: 1039 PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPM 1098
Query: 430 PFPLSLPNHSP 440
LS P SP
Sbjct: 1099 G-DLSCPAPSP 1108
Score = 39.7 bits (91), Expect = 0.018
Identities = 54/197 (27%), Positives = 68/197 (34%), Gaps = 43/197 (21%)
Query: 293 VVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQ- 351
V+ K+P + P Q Q + L R P Q P T P QG Q Q
Sbjct: 4204 VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL 4263
Query: 352 ---PAPQ----PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P PQ ++ PRPQ P P + A P A S L +
Sbjct: 4264 GGFPGPQTGPLQELGAGPRPQGP--------PRLPAPPGALSTGPVLGPVH--------- 4306
Query: 405 SSSRSSTPAKTQPAPPHISHHPSASPFPLS-LPNHSPLHSFTPTLQPPAHSHHPNMFAPP 463
TP + P P PS P P S LP + L PP H P P
Sbjct: 4307 -----PTPPPSSPQEP---KRPSQLPSPSSQLPTEAQL--------PPTHPGTPKP-QGP 4349
Query: 464 TALPPPPPLTSGSLQVA 480
T PPP ++ + Q+A
Sbjct: 4350 TLEPPPGRVSPAAAQLA 4366
Score = 36.6 bits (83), Expect = 0.16
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 295 LKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP-----PLSTQPPQGPPEAQ 349
L P P+ P P P P +P +P + TE +PP PL++ P P+ +
Sbjct: 4906 LSAPPPEEPSPPPSPLA-PSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 350 LQPAPQPQVQRPPR 363
+P + + RPPR
Sbjct: 4965 ARPPEEGEDSRPPR 4978
Score = 36.2 bits (82), Expect = 0.20
Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 14/127 (11%)
Query: 274 LERSQEKSQDCCKEPIF-EPVVLKDP------CPQVAQPIPQPQTEP-QLRAPSPDPDLV 325
++R ++SQ + P + EP P C P PQT P Q P P
Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286
Query: 326 QRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLL--HQNLPPVQAHPS 383
R APP LST P GP P+ + +RP + SP+ L LPP HP
Sbjct: 4287 PRLPAPPGA--LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP--THPG 4342
Query: 384 AQSLSQP 390
P
Sbjct: 4343 TPKPQGP 4349
Score = 35.8 bits (81), Expect = 0.26
Identities = 123/545 (22%), Positives = 170/545 (31%), Gaps = 99/545 (18%)
Query: 317 APSPDPDLVQRTEAPPQP-PPLSTQPPQGPPEAQ-----LQPAPQPQVQRPPRPQSPTQL 370
+PS P L+ T+ P Q P QPPQGPP Q L P +P P T L
Sbjct: 3620 SPSQSPRLL--TKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTAL 3677
Query: 371 LHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLS--------------------SSRSS 410
Q Q A SL+ P + +L+L SL + +
Sbjct: 3678 AQQQ--QQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQ 3735
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPT---LQPPAHSHHPNMFAPPTALP 467
+ Q H+ + P + P L PP S H + +
Sbjct: 3736 QQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPP--SSHQGLLVQQLSPQ 3793
Query: 468 PP--PPLTSGSLQVA----GHPAGSTYSEQDILRQELNT--RFLAS-QSADRGASLGPPP 518
PP P G QVA HP Q RQ L T R L+S Q A +G L
Sbjct: 3794 PPQGPQGMLGPAQVAVLQQQHP--GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHR 3851
Query: 519 YLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHS 578
+ + Q Q QHQ Q + H +
Sbjct: 3852 LVTAQQQQQQQQHQ------QQGSMAGLSH-------------------------LQQSL 3880
Query: 579 LFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDP 638
+ HS P +S P G LQ Q + + + LQ+
Sbjct: 3881 MSHSGQPKLSA-----QPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 639 FRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL--KPEFLSRPPGPSLF 696
+ L++ + Q+ QQ+ ++Q Q + GL + L P
Sbjct: 3936 QQQQLQQQQQQQLQQQQ--QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993
Query: 697 GAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFT-GLAA 755
P A+P FS+ GA PT G N ++PA E PST G A
Sbjct: 3994 QVALGPGMPAKPLQHFSSPGALGPTLLLTG---KEQNTVDPAVSSEATEGPSTHQGGPLA 4050
Query: 756 VGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGEL 815
+G P S+ G VQ P P S PP PG+
Sbjct: 4051 IGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ---------PSSLQLQPPLRLPGQQ 4101
Query: 816 ERSAS 820
++ S
Sbjct: 4102 QQQVS 4106
Score = 34.7 bits (78), Expect = 0.59
Identities = 53/205 (25%), Positives = 70/205 (34%), Gaps = 34/205 (16%)
Query: 314 QLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS-PTQLLH 372
+L P P + +PPP +T QL Q QR P P S P Q
Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQ 2814
Query: 373 QNLPPVQAHPSAQSLSQPLSAYNSSS----LSLNSLS------SSRSSTPAKTQPAPP-- 420
Q L Q +A S+ +SA S+ L +L S+R P + P P
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGP 2874
Query: 421 ----HISHH------PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHP--------NMFAP 462
+ H+ P +PFP P P F P + P H P + P
Sbjct: 2875 AQFIELRHNVQKGLGPGGTPFPGQGPPQRP--RFYPVSEDP-HRLAPEGLRGLAVSGLPP 2931
Query: 463 PTALPPPPPLTSGSLQVAGHPAGST 487
PP P + SL H G T
Sbjct: 2932 QKPSAPPAPELNNSLHPTPHTKGPT 2956
Score = 34.7 bits (78), Expect = 0.59
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Query: 379 QAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPS-ASPFPLSLPN 437
Q P+ + +Q YN S+L + LS+ P +P+PP PS +P P S P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSA-----PPPEEPSPP-----PSPLAPSPASPPT 4930
Query: 438 HSPLHSFT-PTLQPPAHSHHPNMFAPPTALPPP 469
+ T P +PP S P +P +A P P
Sbjct: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Score = 33.5 bits (75), Expect = 1.3
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQ---PPPLSTQP-PQGPPEAQLQPAPQPQVQR 360
P P+P T+ + D+ Q + PP+ PPP P P PP L P +
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQS 386
PP P SP L P A P ++
Sbjct: 4944 PPVP-SPLPLASS---PESARPKPRA 4965
Score = 33.1 bits (74), Expect = 1.7
Identities = 35/140 (25%), Positives = 48/140 (34%), Gaps = 8/140 (5%)
Query: 946 TPVVESARPNSTSS--REAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRAS 1003
TP P S R EP + +P ++ + + PP P+
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP---- 2387
Query: 1004 EPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPY 1063
+PPPP S ++ P L S P + V S S T P P RF
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFS-RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
Query: 1064 PS-FHWDPIRDPLRDPYREL 1082
P + P R RDP+ L
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPL 2466
Score = 31.2 bits (69), Expect = 6.5
Identities = 48/192 (25%), Positives = 65/192 (33%), Gaps = 29/192 (15%)
Query: 375 LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLS 434
L P + P A S+P A + R +P + A P + P+A+ L
Sbjct: 3094 LGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLG 3153
Query: 435 L-----------------PNHSPLH-----SFTPTLQPPAHSHHPNMFAPP--TALPPPP 470
L P S H SF T PPAH P+ + P ++L
Sbjct: 3154 LKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKF 3213
Query: 471 PLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSAD----RGASLGPPPYLRTEFHQ 526
L SG+L + G PA S E D + L L D L L +
Sbjct: 3214 ELESGALTLPGGPAASG-DELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQP 3272
Query: 527 HQHQHQHTHQHT 538
Q Q Q QH+
Sbjct: 3273 AQQQQQQQQQHS 3284
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 63.5 bits (153), Expect = 1e-09
Identities = 51/166 (30%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 310 QTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQ 369
Q+ P+ P P P Q+ P QPPP P Q PP P P Q Q PP PQ ++
Sbjct: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH----PQPHQQQQPPPPPQDSSK 108
Query: 370 LLHQN----LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHH 425
+ P V + P A S + P + S + S P T PP ++
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA--------PPGSGPGPTPTPPPAVTSA 160
Query: 426 PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P +P P +P S PT P A P PP A+P P P
Sbjct: 161 PPGAPPP------TPPSSGVPTTPPQAGGPPP----PPAAVPGPGP 196
Score = 54.7 bits (130), Expect = 6e-07
Identities = 58/164 (35%), Positives = 64/164 (39%), Gaps = 34/164 (20%)
Query: 314 QLRAP-SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLH 372
Q R P P P Q PP PPP Q Q PP Q P P Q PP PQ P Q
Sbjct: 42 QNRGPMGPGPG--QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ-PHQ--- 95
Query: 373 QNLPPVQAHPSAQSLSQPLSAYNSSSL-SLNSLSSSRSSTPAKTQPAPPHISHHPSASPF 431
Q PP P Q S+P+ A + S + SS P T PP P + P
Sbjct: 96 QQQPP----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPAT---PPTSGAPPGSGPG 148
Query: 432 PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSG 475
P TPT P S APP A PPP P +SG
Sbjct: 149 P------------TPTPPPAVTS------APPGA-PPPTPPSSG 173
Score = 37.4 bits (85), Expect = 0.091
Identities = 37/115 (32%), Positives = 39/115 (33%), Gaps = 12/115 (10%)
Query: 516 PPPYLRTEFHQHQHQ---HQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVD 572
PPP HQ Q Q Q Q H P PH P P P P K
Sbjct: 63 PPP------HQQQQQPPPQQPPPQQPPPHQ--PPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
Query: 573 PFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHT 627
P + S PPA S PP PPT G T P +A PG P T
Sbjct: 115 PGPAPGV-GSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPT 168
Score = 36.2 bits (82), Expect = 0.20
Identities = 51/210 (24%), Positives = 57/210 (27%), Gaps = 63/210 (30%)
Query: 417 PAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGS 476
P P P P P P P QPP H P+ PPPPP S
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQ 536
VA P + G PP
Sbjct: 109 PVVAQGPGPAP-----------------------GVGSAPP------------------- 126
Query: 537 HTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPP 596
+ P A PPT + APP PT PPAV+ PP PP
Sbjct: 127 -----ASSSAPPATPPT----SGAPPGSGPGPTPTP-----------PPAVTSAPPGAPP 166
Query: 597 TGPFGSLQGAFQPKTSN-PIDVAARPGTVP 625
P S P+ P AA PG P
Sbjct: 167 PTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
Score = 35.0 bits (79), Expect = 0.45
Identities = 34/112 (30%), Positives = 38/112 (33%), Gaps = 14/112 (12%)
Query: 249 PELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQ 308
P GVG+ P S A P P SG P P V P P P P
Sbjct: 117 PAPGVGSAPPASSS-APPATPPTSGAPPGSGPGPT----PTPPPAVTSAP-PGAPPPTPP 170
Query: 309 ----PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQP 356
P T PQ P P P V P P P P GP ++ P+P
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAV----PGPGPGPKQGPGPGGPKGGKMPGGPKP 218
Score = 30.8 bits (68), Expect = 8.5
Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 954 PNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSS 1013
P S P P ++ ++ + ++ H PP PQ H+ +PPPP SS
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH-PQPHQQQQPPPPPQDSS 107
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 63.5 bits (153), Expect = 1e-09
Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 32/194 (16%)
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQ---------LQ 351
+VAQP P E + P + + + EAP P L+T P G PE+ +
Sbjct: 409 EVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPS-LATSPALGHPESTPKSLHPWYGIT 467
Query: 352 PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSST 411
P P+ ++ P P++P+ P+ H S S S+P SA S +LS+ SLSS +S
Sbjct: 468 PTSSPKTKKRPAPRAPSA------SPLALHASRLSHSEPPSATPSPALSVESLSSESASQ 521
Query: 412 PAKTQ----PAPPHIS-----HHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAP 462
A + PA P S H P P+SL +S L S ++P
Sbjct: 522 TAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQ-------M 574
Query: 463 PTALPPPPPLTSGS 476
P A P P T GS
Sbjct: 575 PQASPGLAPRTRGS 588
Score = 44.3 bits (103), Expect = 7e-04
Identities = 61/223 (27%), Positives = 85/223 (38%), Gaps = 52/223 (23%)
Query: 305 PIPQPQTEPQ----LRAPSPDPDLVQRTEAPPQ--PPPLSTQPPQGPPEAQLQPA----- 353
P+P+P+ P+ AP DP + +A P+ P PL GPP +
Sbjct: 348 PVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGT 407
Query: 354 -----PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSL--SQPLSAYNSSSLSLNSLS- 405
P P +P +P + + + P+A SL S L S+ SL+
Sbjct: 408 EEVAQPSPTASLESKPYNPFE--EEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYG 465
Query: 406 -SSRSSTPAKTQPAPPHISHHPSASPFPL--SLPNHSPLHSFTPT--------------- 447
+ SS K +PAP PSASP L S +HS S TP+
Sbjct: 466 ITPTSSPKTKKRPAP----RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQ 521
Query: 448 ------LQPPA---HSHHPNMFAPPTALPPPPPLTSGSLQVAG 481
L+PPA S P + AP T P T+ SL +G
Sbjct: 522 TAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSG 564
Score = 40.8 bits (94), Expect = 0.008
Identities = 52/238 (21%), Positives = 76/238 (31%), Gaps = 12/238 (5%)
Query: 792 PWNRLHRTPPSF-PTP-PPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK 849
PW L + P P P PP PG + + + +V + + S + K E+
Sbjct: 370 PWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEE 429
Query: 850 RHSSHPSPAPVLPV----NALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLA 905
AP P ALGH S+ + + K K+R + S LA
Sbjct: 430 EEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLA 489
Query: 906 ADEHKAKEGHLPEKDGHG--HEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 963
+ P + E A Q A + + P V +
Sbjct: 490 LHASRLSHSEPPSATPSPALSVESLSSESASQTA--GAELLEPPAVPKSSSEPAVHAPGT 547
Query: 964 PRKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRASEPPPPNSSSSVHPGPL 1019
P N +S ++ E R E P AP+T +S P P S P PL
Sbjct: 548 PGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPL 605
Score = 37.4 bits (85), Expect = 0.091
Identities = 62/261 (23%), Positives = 91/261 (34%), Gaps = 46/261 (17%)
Query: 303 AQPIPQPQTEPQLRAPSPDPDLV----------------QRTEAPPQPPPLSTQPPQGPP 346
A P +PQ + R P +L T APP P P S+ +
Sbjct: 272 ASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLV 331
Query: 347 E---------AQLQPAPQPQVQRPPRPQSPTQLLHQNLP---PVQAHPSAQSLSQPLSAY 394
E +L P P+ + P+P T ++ P VQA P + P S+
Sbjct: 332 EQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSS- 390
Query: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL-QPPAH 453
+ S +S T QP+P +PF + P+L PA
Sbjct: 391 SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPAL 450
Query: 454 SH--------HPNMFAPPTALPP----PPPLTSGSLQVAGHPAGSTYSEQDILRQE--LN 499
H HP PT+ P P P + +A H + ++SE L+
Sbjct: 451 GHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALS 510
Query: 500 TRFLASQSADR--GASLGPPP 518
L+S+SA + GA L PP
Sbjct: 511 VESLSSESASQTAGAELLEPP 531
Score = 34.3 bits (77), Expect = 0.77
Identities = 65/304 (21%), Positives = 102/304 (33%), Gaps = 42/304 (13%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRP 364
P QP+ + Q + D+ + P P+ PEA +PQ+ P +P
Sbjct: 233 PFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEA------RPQI--PTKP 284
Query: 365 QSPTQLLHQNLPPV-----------QAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
+ P +L PP ++ A +P S+ +L + SSS +
Sbjct: 285 RVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRL 344
Query: 414 KTQPAP-PHISHHPS-ASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P P P + PS +P P P L P +P PP++ P PP
Sbjct: 345 HELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAP--------LPPSSSPGPPS 396
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH 531
S ++ G + S L + F + D+ P L T H
Sbjct: 397 QDSRQVENGGTEEVAQPSPTASLESKPYNPF-EEEEEDKEEEAPAAPSLAT---SPALGH 452
Query: 532 QHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHS--LFHSYPPAVSG 589
+ + + P + P T P P P P H+ L HS PP+ +
Sbjct: 453 PESTPKSLHPWYGITPTSSPKTKKRPAPRAP-------SASPLALHASRLSHSEPPSATP 505
Query: 590 IPPM 593
P +
Sbjct: 506 SPAL 509
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 63.2 bits (152), Expect = 2e-09
Identities = 74/258 (28%), Positives = 96/258 (37%), Gaps = 45/258 (17%)
Query: 260 DSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP-----QVAQPIPQPQTEP- 313
+S G VP +G+ D +PV P P Q+A QPQ
Sbjct: 550 ESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG 609
Query: 314 --QL------RAPSPDPDLVQRTEAPPQP-PPLSTQPPQGPPEAQLQPA----PQPQVQR 360
QL A P P ++R P P PP PP G P Q P +
Sbjct: 610 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 669
Query: 361 PPR--PQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
PP P PTQ H PP Q PSA S LSA S SL+ + + P A
Sbjct: 670 PPTRSPSPPTQ--HTGQPPGQ--PSAPS---QLSAPRRYSSSLSPIQAPNHPPPQPPTQA 722
Query: 419 PP--HISHHPSASPFPLSLPN--------HSPLHSFTPTLQPPAHSHHPNMFAPPTALPP 468
P H + P P++LP+ H+P + TP PP +P +LP
Sbjct: 723 TPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-------SLPA 775
Query: 469 PPPLTSGSLQVAGHPAGS 486
P L G+ + A AG+
Sbjct: 776 PQTLAGGNPETAQPHAGT 793
Score = 52.4 bits (124), Expect = 3e-06
Identities = 83/350 (23%), Positives = 112/350 (32%), Gaps = 68/350 (19%)
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG------PPEAQ-LQPAPQPQVQRPPRPQ 365
P + P P D A P+PPP S++ P A L+ P P PP+P+
Sbjct: 521 PAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 580
Query: 366 SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP-------AKTQPA 418
P P A +QP +A S LS+ ++ +P K PA
Sbjct: 581 DPVSAA-VPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPA 639
Query: 419 PPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQ 478
PP + P P S S P+L P PPT P PP +G Q
Sbjct: 640 PPKPGNPPPGHPGGQS---SSGTSQHPPSLSP----------KPPTRSPSPPTQHTG--Q 684
Query: 479 VAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHT 538
G P+ + Q R +S + A PPP T+ H ++
Sbjct: 685 PPGQPSAPS--------QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQG-- 734
Query: 539 HQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTG 598
P P A+P + P S+ P + PP PP G
Sbjct: 735 -----PPNPMALPSEHGLEQP----------------------SHTPPQTPTPPSTPPLG 767
Query: 599 PFG-SLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPG 647
SL NP GT+P PR P + PG
Sbjct: 768 KQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPG 817
Score = 44.3 bits (103), Expect = 7e-04
Identities = 47/158 (29%), Positives = 62/158 (39%), Gaps = 23/158 (14%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQ 357
P QP QP QL AP + +AP P PPQ P +A +P
Sbjct: 678 PTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP------PPQPPTQATPLMHTKPN 731
Query: 358 VQRPPRPQS-PTQL-LHQ--NLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
Q PP P + P++ L Q + PP P + + PL N S + +L+ T
Sbjct: 732 SQGPPNPMALPSEHGLEQPSHTPPQTPTPPS---TPPLGKQNPSLPAPQTLAGGNPET-- 786
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPP 451
A PH P P P+ P + P S P QPP
Sbjct: 787 ----AQPHAGTLP--RPRPVPKPRNRP--SVPPPPQPP 816
Score = 34.3 bits (77), Expect = 0.77
Identities = 43/164 (26%), Positives = 59/164 (35%), Gaps = 14/164 (8%)
Query: 445 TPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLA 504
+P QPP + P A P PPP +S + +G G+ S IL Q + +
Sbjct: 520 SPAFQPPLPPTDGSTVVP--AGPEPPPQSSRAESSSG--GGTVPSSAGILEQGPSPGDGS 575
Query: 505 SQSADRGASLGPPPYLRTEFH----QHQHQ-----HQHTHQHTHQHTFTPFPHAIPPTAI 555
S P R Q+Q Q HQ + H + P PH +
Sbjct: 576 PPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPH-NAAGPSPHTLRRAVK 634
Query: 556 MPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
P PAPP P S +PP++S PP P+ P
Sbjct: 635 KPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPP 678
Score = 30.8 bits (68), Expect = 8.5
Identities = 38/129 (29%), Positives = 47/129 (36%), Gaps = 29/129 (22%)
Query: 690 PPGPSLFGAIHHPHDLA-RPSTLFSAAGAAH---PTGTPFGP-----PPHHSNFLNP--A 738
P G S G HP L+ +P T + H P G P P P +S+ L+P A
Sbjct: 651 PGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQA 710
Query: 739 AHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHR 798
+ P P+ T L N+ G PN M PS P
Sbjct: 711 PNHPPPQPPTQATPLMHTKPNSQG-------PPNPM----ALPSEHGLEQP-------SH 752
Query: 799 TPPSFPTPP 807
TPP PTPP
Sbjct: 753 TPPQTPTPP 761
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 63.2 bits (152), Expect = 2e-09
Identities = 99/415 (23%), Positives = 141/415 (33%), Gaps = 64/415 (15%)
Query: 2 DGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGK 61
DGP R G + R S GA G GR R + G+ E
Sbjct: 1165 DGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLE---- 1220
Query: 62 PPSSAPSRPRPPRRKRRESTSAEEDI--IDGFAMTSFVTFEALEKDVALKPQERVEKRQT 119
P + P+ TS+ + I D ++ S +T E +E + + VE++Q
Sbjct: 1221 PLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKI-----KEVEEKQP 1275
Query: 120 PLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKAL--RQLKP 177
+ K + + L F KS HP Y + L L K +P ++ R L+P
Sbjct: 1276 EM---KSGFMASFLDF--LKSGKRHPPLYQA------GLTPPLSPPKSVPPSVPARGLQP 1324
Query: 178 GQNSCR-------------DSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSD 224
+ E+A E G S +RL + + F +
Sbjct: 1325 QPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDE 1384
Query: 225 SDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIV---------PKISGLE 275
D K D E + + + DP L P+ S GP + P + GL
Sbjct: 1385 EDSVAKNRDLQ-ESISSAISALDDPPLAG---PKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 276 RSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP 335
+ EP +L++ P P P PQ +P P P P L P PP
Sbjct: 1441 SANSNGTP-------EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPAL-------PSPP 1486
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
PL P PP L P P P + PP P P P A PS + P
Sbjct: 1487 PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541
Score = 49.3 bits (116), Expect = 2e-05
Identities = 46/170 (27%), Positives = 60/170 (35%), Gaps = 32/170 (18%)
Query: 325 VQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSA 384
+ + PP P T P GPP A P P PP+ PSA
Sbjct: 1402 ISALDDPPLAGPKDTSTPDGPPLAPAAAVPGP-------------------PPLPGLPSA 1442
Query: 385 QSLSQPLSAYNSSSLSLNSLSSSRSSTPAKT-QPAPPHISHHPSASPFPLSLPNHSPLHS 443
S P L + PA T QP PP P P +LP+ PL +
Sbjct: 1443 NSNGTP-------EPPLLEEKPPPTPPPAPTPQPQPP-----PPPPPPQPALPSPPPLVA 1490
Query: 444 FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDI 493
TP+ PP P A P+ PPPPP + PA + + ++
Sbjct: 1491 PTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Score = 42.7 bits (99), Expect = 0.002
Identities = 100/408 (24%), Positives = 138/408 (33%), Gaps = 68/408 (16%)
Query: 284 CCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP------PL 337
C P P+ D CP P P P P+ R P + + PP+P PL
Sbjct: 1128 CRSRPALSPLGDIDFCP----PNPGPDG-PRRRGRKPTK---AKRDGPPRPRGRPRIRPL 1179
Query: 338 STQPPQGPPEAQLQP--APQPQVQ-----RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
GP A A +P+ + R T+L + L P++ S +
Sbjct: 1180 EVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRL--EPLKPLKIKLSVPKAGEG 1237
Query: 391 LSAYNSSSLS---LNSLSSS--RSSTPAK---TQPAPPHISHHPSAS--PFPLSLPNHSP 440
L + ++S NSL SS R AK + P + AS F S H P
Sbjct: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
Query: 441 LHS--FTPTLQPP--------AHSHHPNMFAPPTALPPPPPLTS----GSLQVA------ 480
L+ TP L PP A P A P A+P PPP + G+L+ A
Sbjct: 1298 LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP-AVPHPPPSGAFGLGGALEAAESEGLG 1356
Query: 481 -GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTH 539
G P+ ++++ R N L S S+D S+ L+
Sbjct: 1357 LGCPSPCKRLDEELKR---NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP 1413
Query: 540 QHTFTPFPHAIPPTAIMPTPAP-PMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTG 598
+ T TP + P A +P P P P + P PP + PP PP
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP---------EPPLLEEKPPPTPPPA 1464
Query: 599 PFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKP 646
P Q P P + P P P L P P + P
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Score = 40.0 bits (92), Expect = 0.014
Identities = 39/146 (26%), Positives = 51/146 (34%), Gaps = 23/146 (15%)
Query: 332 PQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPL 391
P PPP + Q Q P L A P + P P Q LP V +H + S S
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP-----QLLPSVLSHAPSPSPS--- 815
Query: 392 SAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPP 451
+S + ++ L + + P PP P P PL L H H P P
Sbjct: 816 ----ASKVGVHLLEPATRDGAPQPPPPPP-----PPPPPMPLQLEAHLRSHGLEPAAPSP 866
Query: 452 AHSHHPNMFAPPT------ALPPPPP 471
++ P AL P PP
Sbjct: 867 RLRPEESLDPPGAMQELLGALEPLPP 892
Score = 37.4 bits (85), Expect = 0.091
Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 35/232 (15%)
Query: 163 GKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCD 222
G +++ AL L P S + G +RS S + + AP + C
Sbjct: 878 GAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ---GTKAPRFVPLTSICF 934
Query: 223 SDS--DQEEKASDASSEKLFNTVIVNK-----------DPELGVGTLPEHDSQDA-GPIV 268
DS EE++ + E++F + DP+ G G P + D GP
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYC 994
Query: 269 P-KISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQR 327
P + SG + ++ +P P + P A+P+ Q+ P AP P P
Sbjct: 995 PGRASG---AGPETPGLGLDPNKPPEL---PSTVNAEPLGLIQSGPHQAAPPPPP----- 1043
Query: 328 TEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQ 379
PP PPP P+G + + + +P + S LL + PP Q
Sbjct: 1044 ---PPPPPPAPASEPKGGLTSPIFCSTKP---KKLLKTSSFHLLRRRDPPFQ 1089
Score = 35.4 bits (80), Expect = 0.35
Identities = 45/163 (27%), Positives = 56/163 (34%), Gaps = 34/163 (20%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P Q PP PP PP PPR PTQ NL S S
Sbjct: 221 PAQTPPYRPGPPDPPP--------------PPR-HLPTQF---NL--------LASSSAA 254
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAP------PHISHHPSASPFPLSLPNHSPLHSF 444
+A SS L + S + P + P H SA P P P H+ H
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
Query: 445 TPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGST 487
+ P+ H N+ P P P +G AG P+G+T
Sbjct: 315 SCGGSYPSMGHRANLACSPLGGGEPSP-GAGEPSKAG-PSGAT 355
Score = 35.4 bits (80), Expect = 0.35
Identities = 53/211 (25%), Positives = 75/211 (35%), Gaps = 47/211 (22%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQ--RTEAPPQPPPLSTQPPQGPPEAQ 349
P+VL P PQ+ + P A L++ + PQPPP PP PP
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPP---PPPPPPPPMP 847
Query: 350 LQ--------------PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN 395
LQ P+P+ + + P Q L L P+ P + P
Sbjct: 848 LQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPP----- 902
Query: 396 SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQ------ 449
+S + + RS +P T+ AP + ++ FP SL SF PT++
Sbjct: 903 -NSEGKDPAGAYRSPSPQGTK-APRFVP--LTSICFPDSLLQDEE-RSFFPTMEEMFGGG 957
Query: 450 ---------PPAHSHHPNMFAPPTALPPPPP 471
PP P A P PP PP
Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGP---PPGPP 985
Score = 33.9 bits (76), Expect = 1.0
Identities = 48/198 (24%), Positives = 72/198 (36%), Gaps = 48/198 (24%)
Query: 691 PGPSLFGAIHHPHDL-ARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPST 749
P S A HP +RP + S+ P PF PP + + HL+P P+
Sbjct: 143 PSSSALSAYQHPASFGSRPFPVPSSLSLQDP---PFSPPANGLLSPHDVLHLKPSQAPTV 199
Query: 750 FTGLA---AVGGNAFGGLG-NPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPT 805
+ L GG G G P+ TP P+ P P P
Sbjct: 200 PSSLGFERLAGGGVLGPAGLGPAQTP-----------------PYRP-------GPPDPP 235
Query: 806 PPPWLKPGE--LERSASAAAHDRDRDVDK-------------RDSSVSKDDKERESVEKR 850
PPP P + L S+SAAA ++ + + ++ + D + ++
Sbjct: 236 PPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP 295
Query: 851 HSSHPSPAPVLPVNALGH 868
S+ P P P P +AL H
Sbjct: 296 ASAQPPPPPP-PAHALQH 312
Score = 33.5 bits (75), Expect = 1.3
Identities = 42/143 (29%), Positives = 50/143 (34%), Gaps = 31/143 (21%)
Query: 332 PQPPPLSTQ-PPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P P LS Q PP PP L SP +LH L P QA P+ S
Sbjct: 163 PVPSSLSLQDPPFSPPANGLL--------------SPHDVLH--LKPSQA-PTVPS---- 201
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPA--PPHISHHPSASPFPLSLPNHSPLHSFTPTL 448
SL L+ PA PA PP+ P P P LP L + +
Sbjct: 202 -------SLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAA 254
Query: 449 QPPAHSHHPNMFAPPTALPPPPP 471
A P ++ A P PPP
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPP 277
Score = 33.1 bits (74), Expect = 1.7
Identities = 32/154 (20%), Positives = 57/154 (37%), Gaps = 30/154 (19%)
Query: 284 CCKEPIFEPVVLKDPCPQVAQPIPQP-QTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPP 342
C ++P P V Q P+ + P +AP+P PP+P
Sbjct: 1662 CARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP----------PPKPETPEKTTS 1711
Query: 343 QGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLN 402
+ PPE P+ + PP P+ P+ L PV+ + +++
Sbjct: 1712 EKPPEQ----TPETAMPEPPAPEKPSL-----LRPVEKEKEKEKVTR----------GER 1752
Query: 403 SLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLP 436
L R+++ +T+P + P+ S P + P
Sbjct: 1753 PLRGERATSGRQTRPERSLATGQPATSRLPKARP 1786
Score = 32.7 bits (73), Expect = 2.2
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 5/82 (6%)
Query: 1180 PHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPP----LISTLGGRPVSPR 1235
P P P LPS P ++PT + PP A+ +PPP + L P P
Sbjct: 1473 PPPPPPQPALPSPP-PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
Query: 1236 RTTPLSAEIRERPPSHTLKDIE 1257
+P E+ + P H K E
Sbjct: 1532 APSPEDPELPDTRPLHLAKKQE 1553
Score = 31.2 bits (69), Expect = 6.5
Identities = 38/157 (24%), Positives = 47/157 (29%), Gaps = 21/157 (13%)
Query: 467 PPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL-GPPPYLRTEFH 525
PPPPP T+ S Q H L + D L PPP L
Sbjct: 764 PPPPPPTAQSTQPTPHGL-----------------LLEAGGPDLPLVLPPPPPQLLPSVL 806
Query: 526 QHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYR-HSLFHSYP 584
H + H P P P P PP P +++ R H L + P
Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP--PPMPLQLEAHLRSHGLEPAAP 864
Query: 585 PAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARP 621
+ P G L GA +P P D P
Sbjct: 865 SPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
Score = 31.2 bits (69), Expect = 6.5
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 13/71 (18%)
Query: 412 PAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P Q P +SH PS SP + H L+P P PP PPPPP
Sbjct: 796 PPPPQLLPSVLSHAPSPSPSASKVGVH--------LLEPATRDGAPQ--PPPPPPPPPPP 845
Query: 472 LTSGSLQVAGH 482
+ LQ+ H
Sbjct: 846 M---PLQLEAH 853
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 62.8 bits (151), Expect = 2e-09
Identities = 92/391 (23%), Positives = 128/391 (32%), Gaps = 95/391 (24%)
Query: 322 PDLVQRTEAPPQP----PPLSTQPPQGPPEAQLQPAPQPQV----QRPPRPQSPTQLLHQ 373
P + + PP P PP S+ P L P P Q RP QSP Q
Sbjct: 1433 PSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQ 1492
Query: 374 NLPPVQAHPSAQSL-------------SQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
P +P+AQ+L +Q S +S++ S + S S+ P P PP
Sbjct: 1493 REPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPP 1552
Query: 421 HISHHPSASP--------------------------------FPLSLPNH--SPLHSFTP 446
S++ + P ++P H +P H F P
Sbjct: 1553 SSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGH-FLP 1611
Query: 447 TLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ 506
+ P H PP PPP P Q H S + + SQ
Sbjct: 1612 SQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQ 1671
Query: 507 SADRGASLGPPPYLRTEFHQHQHQHQHTH----QHTHQHTFT---PFPHAIPPTAIM--- 556
+A PPP H H H T Q HQH P P PP++++
Sbjct: 1672 TAGHHLPPPPPPPGPAP-HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASG 1730
Query: 557 ------------PTPAPPMF--DKYPTKVDPFYRHSLFHS-------YPPAVSGIPPMIP 595
P PP+F +PT V P+ + H+ + P+ +G +P
Sbjct: 1731 HHTTSAQALHHPPHQGPPLFPSSAHPT-VPPYPSQATHHTTLGPGPQHQPSGTGPHCPLP 1789
Query: 596 PTGPFGSLQGAFQPKTSNPIDVAARPGTVPH 626
TGP QP+ N I G PH
Sbjct: 1790 VTGPH------LQPQGPNSIPTPTASGFCPH 1814
Score = 51.2 bits (121), Expect = 6e-06
Identities = 113/495 (22%), Positives = 160/495 (32%), Gaps = 94/495 (18%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP--QPPPLSTQPPQGPPEAQ 349
P V P + P PQL+A P P + E P P P +T P +Q
Sbjct: 1286 PCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQ 1345
Query: 350 LQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAH--------PSAQSLSQPLSAYNS----S 397
P++ +P P S + P QAH P S A N +
Sbjct: 1346 NTCKSPPKMSKPGSPGS--------VIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKT 1397
Query: 398 SLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN-HSPLHSFTPTLQPPAHSHH 456
L LS++ + +K P H+ + S+ LP+ + LH PP+
Sbjct: 1398 ELQQKQLSNNNQAL-SKNHPPQTHVRN--SSEQLSQKLPSVPTKLHC------PPS---- 1444
Query: 457 PNMFAPPTALPPPPPLTSGSL--QVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL 514
P++ PP + P P+ G L + GS Y SQS G
Sbjct: 1445 PHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHH------------SQSPQVGTPQ 1492
Query: 515 GPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFP-------------HAIPPTAIMPTPAP 561
P R + Q+ +T Q T FT P ++ TA P P P
Sbjct: 1493 REPQ--RNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPP 1550
Query: 562 PMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARP 621
P Y P ++ ++S + +GP +L G +T V
Sbjct: 1551 PPSSSYYQNQQPSANFQNYNQLKGSLS--QQTVFTSGPNQALPGTTSQQT-----VPGHH 1603
Query: 622 GTVPHTLLQKDPRL--------TDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQS 673
T H L ++P + P P PG H+ Q HQQ +
Sbjct: 1604 VTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGP------HLVQQPNSHQQHSVAHVVG 1657
Query: 674 DPHKLDFGLKPEFLSR----PPGPSLFGAIHHPHDLARPSTLFSAAGAAHP----TGTPF 725
H + G + PP P G H H PST A H + P
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717
Query: 726 GPPPHHSNFLNPAAH 740
PPP S+ L H
Sbjct: 1718 PPPPPPSSVLASGHH 1732
Score = 47.4 bits (111), Expect = 9e-05
Identities = 79/334 (23%), Positives = 104/334 (31%), Gaps = 88/334 (26%)
Query: 304 QPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPR 363
Q +P P PS +P + +T A PPP PP PP PAP P + + P
Sbjct: 1597 QTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPP----PP--PP-----PAPGPHLVQQPN 1645
Query: 364 PQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423
+ H P P + SQ T P PP
Sbjct: 1646 SHQQHSVAHVVGPVHAVTPGSHIHSQ---------------------TAGHHLPPPP--- 1681
Query: 424 HHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
P P P +H P H T A H APP PPPPP S+ +GH
Sbjct: 1682 --PPPGPAP---HHHPPPHPSTGLQGLQAQHQHVVNSAPPPP-PPPPP---SSVLASGHH 1732
Query: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTF 543
S +Q+ GPP + + H + Q TH T
Sbjct: 1733 TTS------------------AQALHHPPHQGPPLFPSS---AHPTVPPYPSQATHHTTL 1771
Query: 544 TPFPHAIP----PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
P P P P +P P + + P + P SG P G
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIP-----------TPTASG---FCPHPGS 1817
Query: 600 FGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDP 633
G P+ ++P+ PG +P Q P
Sbjct: 1818 VALPHGVQGPQQASPV-----PGQIPIHRAQVPP 1846
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 62.8 bits (151), Expect = 2e-09
Identities = 92/391 (23%), Positives = 128/391 (32%), Gaps = 95/391 (24%)
Query: 322 PDLVQRTEAPPQP----PPLSTQPPQGPPEAQLQPAPQPQV----QRPPRPQSPTQLLHQ 373
P + + PP P PP S+ P L P P Q RP QSP Q
Sbjct: 1433 PSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQ 1492
Query: 374 NLPPVQAHPSAQSL-------------SQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
P +P+AQ+L +Q S +S++ S + S S+ P P PP
Sbjct: 1493 REPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPP 1552
Query: 421 HISHHPSASP--------------------------------FPLSLPNH--SPLHSFTP 446
S++ + P ++P H +P H F P
Sbjct: 1553 SSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGH-FLP 1611
Query: 447 TLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ 506
+ P H PP PPP P Q H S + + SQ
Sbjct: 1612 SQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQ 1671
Query: 507 SADRGASLGPPPYLRTEFHQHQHQHQHTH----QHTHQHTFT---PFPHAIPPTAIM--- 556
+A PPP H H H T Q HQH P P PP++++
Sbjct: 1672 TAGHHLPPPPPPPGPAP-HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASG 1730
Query: 557 ------------PTPAPPMF--DKYPTKVDPFYRHSLFHS-------YPPAVSGIPPMIP 595
P PP+F +PT V P+ + H+ + P+ +G +P
Sbjct: 1731 HHTTSAQALHHPPHQGPPLFPSSAHPT-VPPYPSQATHHTTLGPGPQHQPSGTGPHCPLP 1789
Query: 596 PTGPFGSLQGAFQPKTSNPIDVAARPGTVPH 626
TGP QP+ N I G PH
Sbjct: 1790 VTGPH------LQPQGPNSIPTPTASGFCPH 1814
Score = 51.2 bits (121), Expect = 6e-06
Identities = 113/495 (22%), Positives = 160/495 (32%), Gaps = 94/495 (18%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP--QPPPLSTQPPQGPPEAQ 349
P V P + P PQL+A P P + E P P P +T P +Q
Sbjct: 1286 PCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQ 1345
Query: 350 LQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAH--------PSAQSLSQPLSAYNS----S 397
P++ +P P S + P QAH P S A N +
Sbjct: 1346 NTCKSPPKMSKPGSPGS--------VIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKT 1397
Query: 398 SLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN-HSPLHSFTPTLQPPAHSHH 456
L LS++ + +K P H+ + S+ LP+ + LH PP+
Sbjct: 1398 ELQQKQLSNNNQAL-SKNHPPQTHVRN--SSEQLSQKLPSVPTKLHC------PPS---- 1444
Query: 457 PNMFAPPTALPPPPPLTSGSL--QVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL 514
P++ PP + P P+ G L + GS Y SQS G
Sbjct: 1445 PHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHH------------SQSPQVGTPQ 1492
Query: 515 GPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFP-------------HAIPPTAIMPTPAP 561
P R + Q+ +T Q T FT P ++ TA P P P
Sbjct: 1493 REPQ--RNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPP 1550
Query: 562 PMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARP 621
P Y P ++ ++S + +GP +L G +T V
Sbjct: 1551 PPSSSYYQNQQPSANFQNYNQLKGSLS--QQTVFTSGPNQALPGTTSQQT-----VPGHH 1603
Query: 622 GTVPHTLLQKDPRL--------TDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQS 673
T H L ++P + P P PG H+ Q HQQ +
Sbjct: 1604 VTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGP------HLVQQPNSHQQHSVAHVVG 1657
Query: 674 DPHKLDFGLKPEFLSR----PPGPSLFGAIHHPHDLARPSTLFSAAGAAHP----TGTPF 725
H + G + PP P G H H PST A H + P
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717
Query: 726 GPPPHHSNFLNPAAH 740
PPP S+ L H
Sbjct: 1718 PPPPPPSSVLASGHH 1732
Score = 47.4 bits (111), Expect = 9e-05
Identities = 79/334 (23%), Positives = 104/334 (31%), Gaps = 88/334 (26%)
Query: 304 QPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPR 363
Q +P P PS +P + +T A PPP PP PP PAP P + + P
Sbjct: 1597 QTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPP----PP--PP-----PAPGPHLVQQPN 1645
Query: 364 PQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423
+ H P P + SQ T P PP
Sbjct: 1646 SHQQHSVAHVVGPVHAVTPGSHIHSQ---------------------TAGHHLPPPP--- 1681
Query: 424 HHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
P P P +H P H T A H APP PPPPP S+ +GH
Sbjct: 1682 --PPPGPAP---HHHPPPHPSTGLQGLQAQHQHVVNSAPPPP-PPPPP---SSVLASGHH 1732
Query: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTF 543
S +Q+ GPP + + H + Q TH T
Sbjct: 1733 TTS------------------AQALHHPPHQGPPLFPSS---AHPTVPPYPSQATHHTTL 1771
Query: 544 TPFPHAIP----PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
P P P P +P P + + P + P SG P G
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIP-----------TPTASG---FCPHPGS 1817
Query: 600 FGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDP 633
G P+ ++P+ PG +P Q P
Sbjct: 1818 VALPHGVQGPQQASPV-----PGQIPIHRAQVPP 1846
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 62.8 bits (151), Expect = 2e-09
Identities = 103/407 (25%), Positives = 132/407 (32%), Gaps = 100/407 (24%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQP-----APQP-----QVQRPPRPQSPTQLLHQNLPPVQA 380
P QPP + PP PP Q QP PQP VQ P P SP Q +H +PP
Sbjct: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHP-SPPQGMH--MPPQLE 366
Query: 381 HPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQ----PAPPHISHHPSASPFPLSLP 436
P P++ ++ +N TP + P+ P + P P P P
Sbjct: 367 TPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP 426
Query: 437 NHSPLHSFTPTLQPPAHSHHPNMFAPPTALP-------PPPPLTSGS--LQVAGHPAGST 487
H+P PN F+ P LP PPPP L V+G P +
Sbjct: 427 QHTP-------------GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPS 473
Query: 488 YSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFP 547
+ FL +S PPP L H Q +P P
Sbjct: 474 H------------LFLEQRSPPPPP---PPPTLLNSSHPVPTQ-------------SPLP 505
Query: 548 HAIPPTAIMPTPAPPMFDK-YPTK--VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQ 604
P A P+F + P + + P + H P + P IPP PF L
Sbjct: 506 FTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPF--LP 563
Query: 605 GAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQ 664
G QP HT P L P P L P + Q Q
Sbjct: 564 GPGQPFLPT------------HT----QPNLQGPLHPPLPPPHQ---------PQPQQPQ 598
Query: 665 QKVKKQMQ---SDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARP 708
Q+ Q Q PH+ +P P P HH H L+ P
Sbjct: 599 QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
Score = 61.2 bits (147), Expect = 6e-09
Identities = 76/275 (27%), Positives = 96/275 (34%), Gaps = 49/275 (17%)
Query: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRP----- 361
P+P PQ R P P P+ Q T P P +QPP+ P + Q + P PQ + P
Sbjct: 410 PRPAVGPQ-RFPGP-PEFPQHTPGPV--PNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGV 465
Query: 362 -PRPQSPTQL-LHQNLPPV---------QAHP----SAQSLSQPLSAYNSSSLSLNSLSS 406
P+ P+ L L Q PP +HP S +QP A+N
Sbjct: 466 SGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQ-PVFPR 524
Query: 407 SRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTAL 466
R PA P P I H S P + F P QP F P
Sbjct: 525 ERPVRPALQPPGPVGILH--------FSQPGSATTRPFIPPRQP---------FLPGPGQ 567
Query: 467 PPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQ 526
P P T +LQ HP Q +Q Q + PP + H
Sbjct: 568 PFLPTHTQPNLQGPLHPPLPP-PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP 626
Query: 527 HQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAP 561
QH QH H H H H ++PP +MP P
Sbjct: 627 PQHPPQHQHHHHHHHL------SVPPPPLMPMSQP 655
Score = 52.0 bits (123), Expect = 4e-06
Identities = 64/244 (26%), Positives = 75/244 (30%), Gaps = 58/244 (23%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPD-------------------LVQRTEAPPQPPPLS 338
P P P+ + Q RAP P D L QR+ PP PPP
Sbjct: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTL 491
Query: 339 TQ-----PPQGP-PEAQLQPAPQPQVQRP--PR---------PQSPTQLLHQNLPPVQAH 381
P Q P P Q PA Q Q+P PR P P +LH + P
Sbjct: 492 LNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATT 551
Query: 382 -----PSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLP 436
P L P + + N P QP P P P P P
Sbjct: 552 RPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQP----QQPQQQPPPQHQP 607
Query: 437 NHSPLHSFTPTLQPPA-------------HSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
H P H P QPP H HH PP +P P +Q A
Sbjct: 608 PHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQ 667
Query: 484 AGST 487
A S+
Sbjct: 668 ASSS 671
Score = 50.8 bits (120), Expect = 8e-06
Identities = 54/186 (29%), Positives = 70/186 (37%), Gaps = 16/186 (8%)
Query: 300 PQVAQPIPQPQTEPQLRAPS----PDPDLVQRTEAPPQPPPLSTQPPQGP--PEAQLQPA 353
P QP T+P L+ P P P Q + QPPP P Q P P Q QP
Sbjct: 563 PGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPP 622
Query: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
PQ Q PP+ Q H ++PP P +Q +P + SSSR P
Sbjct: 623 PQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRP-----HVQTAQPQASSSRMQCPQ 677
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPP---P 470
+ S + S P P +P +S L P A SH M + + P
Sbjct: 678 RQGLRHNTTSQNVSKRPMQQMQPT-APRNSNLREL-PIAPSHVIEMSSSRCSATPSAQVK 735
Query: 471 PLTSGS 476
P+ S S
Sbjct: 736 PIVSAS 741
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/153 (30%), Positives = 55/153 (35%), Gaps = 23/153 (15%)
Query: 298 PCPQVAQPIPQPQTEPQLRAP-SPDPDLVQRTEAPPQPPP----------LSTQPPQGPP 346
P PQ Q P PQ +P + P P P + PPQ PP LS PP P
Sbjct: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMP 651
Query: 347 EAQLQPAPQPQVQRP----PRPQSP-TQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL 401
+Q Q P Q +P R Q P Q L N QP + NS+ L
Sbjct: 652 MSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLREL 711
Query: 402 N-------SLSSSRSSTPAKTQPAPPHISHHPS 427
+SSSR S Q P + PS
Sbjct: 712 PIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744
Score = 36.2 bits (82), Expect = 0.20
Identities = 40/166 (24%), Positives = 55/166 (33%), Gaps = 36/166 (21%)
Query: 1005 PPPPNSSSSVHPGPLAS-MPMTV---------------------------GVTGIHPMNS 1036
PPPP +S HP P S +P T G GI +
Sbjct: 486 PPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQ 545
Query: 1037 ISSLDRTRMMTPFMGISPLPGGERFP---YPSFHWDPIRDPLRDPYRELDIHRRDPLGRD 1093
S + P P PG P P+ P+ PL P++ +
Sbjct: 546 PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQ-GPLHPPLPPPHQPQPQQPQQQPPPQ 604
Query: 1094 FLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDP 1139
+ P H+ P ++ + P + HHHHHHH LSV P
Sbjct: 605 HQPPHQPPHQ--PPPQHQPPPQHPPQHPPQHQHHHHHHH--LSVPP 646
Score = 32.3 bits (72), Expect = 2.9
Identities = 109/569 (19%), Positives = 168/569 (29%), Gaps = 129/569 (22%)
Query: 507 SADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDK 566
S+ RG G P R Q + + H+ P + P A P P PP
Sbjct: 272 SSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQP 331
Query: 567 YPTKVDPFYRHSLF------HSYPPAVSGIPPMI---------PPTGP------------ 599
+ P L H PP +PP + PP P
Sbjct: 332 IRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHF 391
Query: 600 ----FGSLQGAFQPKTSNPIDVAA-------------RPGTVPHTLLQKDPRLTDPFRPM 642
+Q P S P PG VP++ Q PRL P +
Sbjct: 392 KGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQP-PRL--PLQDQ 448
Query: 643 LRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSR-----------PP 691
R P DP L +P F S PP
Sbjct: 449 WRAP---------------------PPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP 487
Query: 692 GPSLFGAIH-----HPHDLARPSTLFSAAGA--AHPTGTPFGP---PPHHSNFLNPAAHL 741
P+L + H P +P F+ G P P P PP L+
Sbjct: 488 PPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILH----- 542
Query: 742 EPFNRPSTFTGLAAVGGNA--FGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRT 799
F++P + T + G G P + P + GP PH+P + +
Sbjct: 543 --FSQPGSATTRPFIPPRQPFLPGPGQPFL-PTHTQPNLQGPLHPPLPPPHQPQPQQPQQ 599
Query: 800 PPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAP 859
P PP P H + + + H P P
Sbjct: 600 QPPPQHQPPHQPP-----------HQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPP 648
Query: 860 VLPVNALGHTRSSTEQIRAHLNTEAREKDK-----PKERERDHSESRKDLAADEHKAKEG 914
++P+ S Q R H+ T + P+ + H+ + ++++ + +
Sbjct: 649 LMPM--------SQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQP 700
Query: 915 HLPEKDGHGHEGRAAGE----EAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPA 970
P A + + + PS V+ P+V SA P S + + +G+
Sbjct: 701 TAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVK-PIV-SASPPSRAVAGSRSSQGKTE 758
Query: 971 YENPKKSSEVKVKEERKEDHDLPPEAPQT 999
+ S + KEE K + + P E +T
Sbjct: 759 VKVKPASPVAQPKEEAKTETEFPDEDEET 787
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 61.6 bits (148), Expect = 5e-09
Identities = 120/492 (24%), Positives = 159/492 (32%), Gaps = 126/492 (25%)
Query: 292 PVVLKDPCPQ----VAQPIP----QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST---- 339
PV+ P PQ V+ P+P QPQ + +AP+P + P P L++
Sbjct: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEK 676
Query: 340 ----QPPQGPPEAQLQP------APQPQVQRPPRPQSPTQLLHQNLPP---VQAHPSAQS 386
QPP P A L PQ + Q+P + P H ++P V A P AQ
Sbjct: 677 IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP----HLSVPASVIVSAPPPAQD 732
Query: 387 LSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA-----------------------PPHI- 422
+ + L + S S PA PA PH+
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 423 SHHPSASPF-----PLSL---PNHSPLHSFTPTLQPPAHSHHPNMF-------------- 460
S HP+ P P S+ P+ PLH P PP P +F
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPT---LPGIFVIQNQLGVPPPASN 849
Query: 461 -APPTALPPPPPL------TSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGAS 513
AP PP PPL G L A H S+ S E ++R A +D
Sbjct: 850 PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD---- 905
Query: 514 LGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFD----KYPT 569
+ +F Q H+ T P H +P A P P P F +P
Sbjct: 906 ------FQLQFPPSQGPHK-------SPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA 952
Query: 570 KVDPFYRHSLFHSYPPAV-----SGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPG-- 622
P FH P + +G P P T SL P S + A G
Sbjct: 953 LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTST--SLGPLTSPAASVLVSGQAPSGTP 1010
Query: 623 TVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHK---LD 679
T P P P+L K A ++ V K S P K L
Sbjct: 1011 TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL--------NVAKAASSGPGKPSGLQ 1062
Query: 680 FGLKPEFLSRPP 691
+ K L +PP
Sbjct: 1063 YESKLSGLKKPP 1074
Score = 58.5 bits (140), Expect = 4e-08
Identities = 131/517 (25%), Positives = 181/517 (35%), Gaps = 97/517 (18%)
Query: 309 PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT 368
P T QL A +P L + A P P G A + A QV +P Q P
Sbjct: 503 PHTGGQLIA---NPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPV 559
Query: 369 QLLHQNLP----PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSS-RSSTPAK-TQPAPPHI 422
L +LP P A P+A ++ Q ++ S+ LN+ + +TPA T A P +
Sbjct: 560 SLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVL 619
Query: 423 SHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP---LTSGSLQV 479
+ P A P ++ PL P Q P + P APP A P P +S V
Sbjct: 620 TVQP-APQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIV 678
Query: 480 AGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTH 539
G P +T + IL Q+ FL + + + S
Sbjct: 679 LGQPPSATPTA--ILTQDSLQMFLPQERSQQPLS-------------------------- 710
Query: 540 QHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIP---PMIPP 596
PH P +++ + PP D P P + + P P P IP
Sbjct: 711 ----AEGPHLSVPASVIVSAPPPAQD--PAPATPVAKGAGLGPQAPDSQASPAPAPQIPA 764
Query: 597 TGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHI 656
P L+G P +S + A G PH P P RP R P +
Sbjct: 765 AAP---LKGP-GPSSSPSLPHQAPLGDSPHL---PSPH---PTRPPSRPPSR-------- 806
Query: 657 AWQIYHHQQKVKKQMQSDP-HKLDFGLKPEFLSRPPGPSLF---GAIHHPHDLARPSTLF 712
Q V + P H P + P P +F + P + P+
Sbjct: 807 -------PQSVSRPPSEPPLHPC-----PPPQAPPTLPGIFVIQNQLGVPPPASNPAP-- 852
Query: 713 SAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPN 772
+A G P P PP L PA HL P + S AV ++ P+ TP
Sbjct: 853 TAPGPPQPPLRPQSQPPEGP--LPPAPHLPPSSTSS------AVASSSETSSRLPAPTP- 903
Query: 773 SMFGHKDGPSVQNFSNPHEPWNRLHRTP-PSFPTPPP 808
S F + PS +P P LH P P+ P PPP
Sbjct: 904 SDFQLQFPPSQGPHKSPTPP-PTLHLVPEPAAPPPPP 939
Score = 49.3 bits (116), Expect = 2e-05
Identities = 81/319 (25%), Positives = 111/319 (34%), Gaps = 92/319 (28%)
Query: 200 SSSRERLSDSSAPSSLGTGY--------FCDSDSDQEEKASDASSEKLFNTVIVNKDPEL 251
+SS E++ PS+ T F + Q+ +++ + +VIV+ P
Sbjct: 671 ASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPP- 729
Query: 252 GVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVV-----LKDPCPQVAQPI 306
+QD P P G + + D P P + LK P P + +
Sbjct: 730 ---------AQDPAPATPVAKGAGLGPQ-APDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
Query: 307 PQ----------PQTEPQLRAPSPDPDLVQRTEAPPQPPPLST-QPPQGPP--------E 347
P P P R PS P Q PP PPL PPQ PP +
Sbjct: 780 PHQAPLGDSPHLPSPHPT-RPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQ 838
Query: 348 AQL-------QPAP------QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAY 394
QL PAP QP ++ P+ Q P LPP P
Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLR--PQSQPP----EGPLPPAPHLPP----------- 881
Query: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS 454
+S+S ++ S S + S PA P+ S F L P H +PT P H
Sbjct: 882 SSTSSAVASSSETSSRLPA------------PTPSDFQLQFPPSQGPHK-SPTPPPTLH- 927
Query: 455 HHPNMFAPPTALPPPPPLT 473
+ P A PPPPP T
Sbjct: 928 ----LVPEPAAPPPPPPRT 942
Score = 45.1 bits (105), Expect = 4e-04
Identities = 145/635 (22%), Positives = 196/635 (30%), Gaps = 164/635 (25%)
Query: 305 PIPQPQTEPQLRAPS-------PDPDLV-QRTEAPPQPPPLSTQPPQ---------GPPE 347
P P +P AP P P+++ RT P QP P PP+ P
Sbjct: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
Query: 348 AQL--QPAPQPQVQRPPRPQS------------------PTQLLHQNL---PPVQAHPSA 384
A L Q P Q+P PQ+ P L N+ PP +A
Sbjct: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
Query: 385 Q-----SLSQPLSAY---NSSSLSLNS-------------------LSSSRSSTPAKT-- 415
+LS+P+S + SS+ + + L S+ PA
Sbjct: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
Query: 416 ---QPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP--PAHSHH-----PNMFAPPTA 465
A PH A+P + PL S P L P AHS H P P
Sbjct: 496 QILAAAAPHTGGQLIANPILTNQNLAGPL-SLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
Query: 466 LPPPPPLTSGSLQVAGHPAGSTYSEQDILR---------QELNTRFLASQSADRGASLG- 515
P L +GSL PA + + +L+ LNT Q A A+ G
Sbjct: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
Query: 516 ------------PPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPH-AIPPTAIMPTPAPP 562
PP + T Q Q Q P P A PP A P P+P
Sbjct: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQAAAPPQATTPQPSPG 669
Query: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF--GSLQGAF-QPKTSNPIDVAA 619
+ P K+ V G PP PT SLQ Q ++ P+
Sbjct: 670 LASS-PEKI---------------VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713
Query: 620 RPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLD 679
+VP +++ P P + A +A Q Q P
Sbjct: 714 PHLSVPASVIVSAP-----------PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI 762
Query: 680 FGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAA 739
P + PGPS ++ H L L S HPT P PP + P +
Sbjct: 763 PAAAP---LKGPGPSSSPSLPHQAPLGDSPHLPS----PHPTRPPSRPPSRPQSVSRPPS 815
Query: 740 H-----LEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWN 794
P P T G+ + LG P N P +P
Sbjct: 816 EPPLHPCPPPQAPPTLPGIFVIQNQ----LGVPPPASN---------PAPTAPGPPQPPL 862
Query: 795 RLHRTPPSFPTPP-PWLKPGELERSASAAAHDRDR 828
R PP P PP P L P + ++++ R
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Score = 38.5 bits (88), Expect = 0.041
Identities = 50/186 (26%), Positives = 69/186 (37%), Gaps = 23/186 (12%)
Query: 312 EPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLL 371
+ QL PD + V + + P S++ + P L + +PP P PT+L
Sbjct: 1190 DKQLAKEKPD-EYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP-PHLPTKL- 1246
Query: 372 HQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAP------PHISHH 425
V H A A SSSLS +S SSS +S+ + P P I +
Sbjct: 1247 ------VIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTY 1300
Query: 426 PSASPFPLSLPNHSP------LHS--FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSL 477
+ S L L +H+ P QPP + PP PPPPP T
Sbjct: 1301 EARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMN 1360
Query: 478 QVAGHP 483
HP
Sbjct: 1361 GTVDHP 1366
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 60.8 bits (146), Expect = 8e-09
Identities = 231/1055 (21%), Positives = 338/1055 (32%), Gaps = 193/1055 (18%)
Query: 102 LEKDVALKPQERVEKRQTPLTKKKREALTNGL---------SFHSKKSR-LSHPHHYSSD 151
+E D++ +E E+RQ + + L G S H K+ SHP S
Sbjct: 41 MEADLSQLSEE--ERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGR 98
Query: 152 RENDRNLCQHLGKRKKMPKALR--QLKPGQNSCRDSDSESASG-ESKGFHRSSSRER-LS 207
+ Q + + R Q PG++ S ES S + K H+SS LS
Sbjct: 99 PPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLS 158
Query: 208 DSSAPSSLGT--GYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAG 265
+ +A S++ + F D + +AS + K +V K+ G + Q
Sbjct: 159 EVNALSAVSSVVNKFNPFDLISDSEASQEETTK--KQKVVQKEQGKPEGIIKPPLQQQPP 216
Query: 266 PIVPKISGLERSQEKSQDCCKEPIF--EPVVLKDPCPQVAQPIPQPQTEPQ--------- 314
+PK G R + QD + I +P +K P +PI P PQ
Sbjct: 217 KPIPKQQGPGRDPLQ-QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
Query: 315 -------------LRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRP 361
+R S P L ++ P Q P P Q P + QP P + P
Sbjct: 276 RDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP---AKPP 332
Query: 362 PRPQSPTQLLHQN----LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP 417
+P T+ L Q PPVQ + + +QPL + S S K
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA 392
Query: 418 APPHISHHPSASPFP-------------------LSLPNHSPLHSFTPTLQP-----PAH 453
PP + P+ P P L P +P + TP QP PA
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 454 SHHPNMFA--------PPTALP---PPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRF 502
P + PP+ LP PPP G + GS
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS---------------- 496
Query: 503 LASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPP 562
A + + S PPP Q T + Q P + P+A P+PA P
Sbjct: 497 -AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ------PGSAKPSAQQPSPAKP 549
Query: 563 MFDKYPTKVDPFYRHSLFHSYPPAVS---------GIPPMIPPTGPFGSL------QGAF 607
+ V S PP VS G+P I P L + F
Sbjct: 550 SAQQSTKPVS--QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF 607
Query: 608 QPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKV 667
T V + G P +P LT+ + A+ +A Q K+
Sbjct: 608 NTCTECQTTVCSLCGFNP------NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
Query: 668 K--------------KQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFS 713
K Q Q K D K + LS+ P P P L + TL
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD-LSKAPEPK------KPPPLVKQPTLHG 714
Query: 714 AAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPS---VT 770
+ A PP + PA EP A + P+ V+
Sbjct: 715 SPSAKAK------QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Query: 771 PNSMFGHKDGPSVQNFSNPHE---PWNRLHRTPPSFPTPPPWLKPGELERSA-SAAAHDR 826
+S D PS + S E P + PS PP K + A A D
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828
Query: 827 DRDVDKRDSSVSKDDKERESVEKRH-----SSHPSPAP-VLPVNALGHTRSSTEQIRAHL 880
SS SK K+ + V+K+ + SP P P+ T
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888
Query: 881 NTEAREKDKPKERERDHS-------ESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEA 933
++ KP+E+ R S ++ K + G L G G +
Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL---FGFGASIFSQASNL 945
Query: 934 KQLARVPSPYVRT----PVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKED 989
A P P+ ++ P+ ++ P+ + + P+ A P KS VK + +
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
Query: 990 HDLPPEAPQ------THRASEPPPPNSSSSVHPGP 1018
L P+A Q T +PPP S S+ P
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
Score = 49.3 bits (116), Expect = 2e-05
Identities = 48/174 (27%), Positives = 62/174 (35%), Gaps = 13/174 (7%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQ 357
P Q+ P + P P + + PP PPP PP PP P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP-----PPPPPP 2426
Query: 358 VQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSS-LSLNSLSSSRSSTPAKTQ 416
+ PP PT L + L +A L ++ +++ L N L +R T A
Sbjct: 2427 LP-PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA-PP 2484
Query: 417 PAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
P PP S PS F H P S P P P PT + P P
Sbjct: 2485 PVPPKPSSIPSGLVF-----THRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 11/95 (11%)
Query: 328 TEAPPQPPPLSTQPPQGPPEAQL-QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQS 386
T APP PP + P G +P+ P +P PQ PT P HP
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT----TQKPTDIHPKPTG 2535
Query: 387 LSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPH 421
LS +SS++LN ++S+ P+ T P PH
Sbjct: 2536 LSL------TSSMTLNLVTSADYKLPSPTSPLSPH 2564
Score = 33.5 bits (75), Expect = 1.3
Identities = 73/348 (20%), Positives = 127/348 (36%), Gaps = 49/348 (14%)
Query: 713 SAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPN 772
+AA AA + G P H + A L + +AAV A GL SV P
Sbjct: 17 AAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEER-RQIAAVMSRA-QGLPKGSVPPA 74
Query: 773 SMFGHKDGPSV---QNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRD 829
+ + PS+ Q + H P P P P L +S + ++
Sbjct: 75 AA----ESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPG------LSKSRTTDTFRSEQK 124
Query: 830 VDKRDSSVS--KDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAH---LNTEA 884
+ R S K+ K R +++ H S P + VNAL S + ++EA
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 885 REKDKPKERERDHSESRKD---LAADEHKAKEGHLPEKDGHG-----HEGRAAGEEAKQL 936
+++ K+++ E K + + +P++ G G +G ++Q
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
Query: 937 ARVPSP----------YVRTPVVESAR------PNSTSSREAEPRKGEPAYENPKKSSEV 980
++ S +TP + A+ + +++A+ +GE + S+
Sbjct: 245 EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
Query: 981 KVKEERKEDHDLPPEAPQTHRASEPPP--PNSSSSVHPGPLASMPMTV 1026
+++ PP H S+P P P + S PLA P TV
Sbjct: 305 PIQQPTP---GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
Score = 33.5 bits (75), Expect = 1.3
Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 8/108 (7%)
Query: 317 APSPDPDLVQRTEAPPQPPPLSTQPP--QGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQN 374
A P P AP + P +QPP QGPP++ Q P P P + ++ +
Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
Query: 375 LPPVQAHPS---AQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAP 419
P + P+ ++ +P +S SL + ++ P K + +P
Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSL---TAEPQKAVLPTKLEKSP 1053
Score = 33.1 bits (74), Expect = 1.7
Identities = 164/760 (21%), Positives = 238/760 (31%), Gaps = 155/760 (20%)
Query: 335 PPLSTQPPQGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSA 393
PP + + P + +L + P Q RPP P P Q S Q L
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP----- 126
Query: 394 YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN-----HSPLHSFTP-- 446
S S SL S+S T K + H S P LS N S ++ F P
Sbjct: 127 --GRSPSTISLKESKSRTDLKEE-------HKSSMMPGFLSEVNALSAVSSVVNKFNPFD 177
Query: 447 ----------------TLQPPAHSHHPNMFAPPTALPPPPPLTSGS------LQVAGHPA 484
+ + PP PP P+ LQ G P
Sbjct: 178 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK 237
Query: 485 GSTYSEQDILRQELNTRFLASQSADRGASL-GPPPYLRTEFHQHQHQHQHTHQHTHQHTF 543
+ + + ++ SQ G + GP +T+ + Q + T Q
Sbjct: 238 SISSQQPEKIK---------SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI 288
Query: 544 TPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSL 603
P +P+P+ P + PT P + P P PP P G
Sbjct: 289 VRGESVKPS---LPSPSKPPIQQ-PTPGKPPAQQPGHEKSQPG-----PAKPPAQPSGLT 339
Query: 604 QG-AFQPKTSNPIDVAARPGTVPHTLLQKDP-RLTDPFRPMLRKPGKWCAMHVHIAWQIY 661
+ A QP T P PGT K P + P +P ++ G +
Sbjct: 340 KPLAQQPGTVKP--PVQPPGTT------KPPAQPLGPAKPPAQQTGS----------EKP 381
Query: 662 HHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSL--FGAIHHPHDLARPSTLFSAAGAAH 719
+Q K + P G P ++ PGP+ + P LA+ L S A A
Sbjct: 382 SSEQPGPKALAQPP---GVGKTP---AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 720 PTGTPF---GPPPHHSNFLNP----AAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPN 772
PT TP GP + P A P PS G A G P+ P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG----PAKPPP 491
Query: 773 SMFGHKDGPSVQNFSNPHEPWNRLHRTP-PSFP--TPPPWLKPGELERSASA------AA 823
G PS Q S P P P P T PP +PG + SA +A
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 824 HDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTE 883
+ V + S K+ S P + P+ +T ++ H+ +
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-------CNTTELLLHVPEK 604
Query: 884 AREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDG----HGHEGRAAGEEAKQLARV 939
A +E + + + HL E + RA G + +
Sbjct: 605 ANFNTC--------TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 940 PSPYVRTPVV--------ESARPNSTS-----------SREAEPRKGEPAYENPKKSSEV 980
P P ++T V S +P TS S+ EP+K P + P
Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 981 KVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 1020
K ++ PPEA + + P P+ S P+A
Sbjct: 717 SAKAKQ------PPEADSLSKPAPPKEPSVPSEQDKAPVA 750
Score = 33.1 bits (74), Expect = 1.7
Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 6/92 (6%)
Query: 381 HPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSP 440
HP + ++ P+ L++ + T + +PA S PS S P
Sbjct: 2342 HPPSSVIALPMKE------QLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFR 2395
Query: 441 LHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL 472
S + QPP P PP PPPPPL
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Score = 32.0 bits (71), Expect = 3.8
Identities = 54/225 (24%), Positives = 86/225 (38%), Gaps = 33/225 (14%)
Query: 23 ERRSRGGLGAGAAGGGGAGRTRALSLAS------SSGSDKEDNGKPPSSAPSRPRPPRRK 76
E RSRG + T S++S SS S K+ K A RP P
Sbjct: 1709 EDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLP 1768
Query: 77 RRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQER---VEKRQTPLTKKKREALTNGL 133
E +S EE E E++ LK QE+ +E++Q + KK + + L
Sbjct: 1769 TIEDSSEEE--------------ELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDEL 1814
Query: 134 SFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGE 193
++ R P S E D + + L + +M + R +SC + S S +
Sbjct: 1815 RAQRRRERPKTPPSNLSPIE-DASPTEELRQAAEMEELHR------SSCSEY-SPSIESD 1866
Query: 194 SKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEK 238
+GF S E++ + L T S +D++ S+K
Sbjct: 1867 PEGF--EISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQK 1909
Score = 32.0 bits (71), Expect = 3.8
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 16/80 (20%)
Query: 325 VQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ-RPPRPQSPTQ-------------- 369
++R PQ PPQ E+QL P P Q + P PTQ
Sbjct: 3853 IERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQ 3912
Query: 370 -LLHQNLPPVQAHPSAQSLS 388
L HQ + P Q P+ Q+++
Sbjct: 3913 TLYHQQVSPYQTQPTFQAVA 3932
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,853,828
Number of Sequences: 37866
Number of extensions: 4546826
Number of successful extensions: 54529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 513
Number of HSP's successfully gapped in prelim test: 1915
Number of HSP's that attempted gapping in prelim test: 24999
Number of HSP's gapped (non-prelim): 19195
length of query: 1259
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1145
effective length of database: 13,930,794
effective search space: 15950759130
effective search space used: 15950759130
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.