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Search of human proteins with 28872756
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872756 fibroblast growth factor 14 isoform 1B [Homo
sapiens]
(252 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 523 e-149
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 377 e-105
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 286 2e-77
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 285 2e-77
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 284 5e-77
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 284 5e-77
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 284 5e-77
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 281 5e-76
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 279 1e-75
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 278 4e-75
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 235 2e-62
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 125 3e-29
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 123 1e-28
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 121 5e-28
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 98 6e-21
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 97 1e-20
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 96 4e-20
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 92 3e-19
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 87 1e-17
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 87 1e-17
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 86 2e-17
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 2e-16
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 84 2e-16
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 2e-16
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 2e-16
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 74 9e-14
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens] 55 6e-08
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens] 50 1e-06
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 50 2e-06
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 49 4e-06
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 523 bits (1347), Expect = e-149
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MVKPVPLFRRTDFKLLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGK 60
MVKPVPLFRRTDFKLLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGK
Sbjct: 1 MVKPVPLFRRTDFKLLLCNHKDLFFLRVSKLLDCFSPKSMWFLWNIFSKGTHMLQCLCGK 60
Query: 61 SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA 120
SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA
Sbjct: 61 SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA 120
Query: 121 IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL 180
IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL
Sbjct: 121 IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL 180
Query: 181 NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM 240
NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM
Sbjct: 181 NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM 240
Query: 241 NGGKPVNKSKTT 252
NGGKPVNKSKTT
Sbjct: 241 NGGKPVNKSKTT 252
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 377 bits (967), Expect = e-105
Identities = 184/190 (96%), Positives = 185/190 (97%)
Query: 63 KKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 122
K+ DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ
Sbjct: 58 KRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 117
Query: 123 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 182
GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK
Sbjct: 118 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 177
Query: 183 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 242
EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG
Sbjct: 178 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 237
Query: 243 GKPVNKSKTT 252
GKPVNKSKTT
Sbjct: 238 GKPVNKSKTT 247
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 286 bits (731), Expect = 2e-77
Identities = 138/194 (71%), Positives = 162/194 (83%), Gaps = 5/194 (2%)
Query: 58 CGKSLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLR 117
C + + +PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLR
Sbjct: 55 CSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLR 114
Query: 118 VVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
VVAIQGVK LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWF
Sbjct: 115 VVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 174
Query: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSAS 237
LGLNKEGQ MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S +
Sbjct: 175 LGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGT 229
Query: 238 AIMNGGKPVNKSKT 251
MNGGK VN+ T
Sbjct: 230 PTMNGGKVVNQDST 243
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 285 bits (730), Expect = 2e-77
Identities = 137/182 (75%), Positives = 159/182 (87%), Gaps = 5/182 (2%)
Query: 70 DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLY 129
+PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQGVK LY
Sbjct: 5 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
Query: 130 IAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG 189
+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKEGQ MKG
Sbjct: 65 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
Query: 190 NRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKS 249
NRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S + MNGGK VN+
Sbjct: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGGKVVNQD 179
Query: 250 KT 251
T
Sbjct: 180 ST 181
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 284 bits (727), Expect = 5e-77
Identities = 134/190 (70%), Positives = 159/190 (83%)
Query: 63 KKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 122
K+N P +PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 37 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 96
Query: 123 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 182
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 97 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 156
Query: 183 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 242
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 157 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
Query: 243 GKPVNKSKTT 252
GK ++ +++T
Sbjct: 217 GKSMSHNEST 226
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 284 bits (727), Expect = 5e-77
Identities = 134/190 (70%), Positives = 159/190 (83%)
Query: 63 KKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 122
K+N P +PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 37 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 96
Query: 123 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 182
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 97 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 156
Query: 183 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 242
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 157 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
Query: 243 GKPVNKSKTT 252
GK ++ +++T
Sbjct: 217 GKSMSHNEST 226
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 284 bits (727), Expect = 5e-77
Identities = 134/190 (70%), Positives = 159/190 (83%)
Query: 63 KKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 122
K+N P +PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 66 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 125
Query: 123 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 182
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 126 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 185
Query: 183 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 242
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 186 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 245
Query: 243 GKPVNKSKTT 252
GK ++ +++T
Sbjct: 246 GKSMSHNEST 255
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 281 bits (718), Expect = 5e-76
Identities = 133/192 (69%), Positives = 159/192 (82%)
Query: 61 SLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVA 120
S K+ + +PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVA
Sbjct: 54 SKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVA 113
Query: 121 IQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGL 180
IQGV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGL
Sbjct: 114 IQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGL 173
Query: 181 NKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIM 240
NKEG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++
Sbjct: 174 NKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVL 233
Query: 241 NGGKPVNKSKTT 252
NGGK ++ +++T
Sbjct: 234 NGGKSMSHNEST 245
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 279 bits (714), Expect = 1e-75
Identities = 132/187 (70%), Positives = 158/187 (84%)
Query: 66 KNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 125
K+ ++PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQGV+
Sbjct: 6 KSYSEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQ 65
Query: 126 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 185
T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNKEG+
Sbjct: 66 TKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGE 125
Query: 186 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 245
MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NGGK
Sbjct: 126 IMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKS 185
Query: 246 VNKSKTT 252
++ +++T
Sbjct: 186 MSHNEST 192
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 278 bits (710), Expect = 4e-75
Identities = 131/183 (71%), Positives = 155/183 (84%)
Query: 70 DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLY 129
+PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQGV+T LY
Sbjct: 17 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 76
Query: 130 IAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG 189
+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNKEG+ MKG
Sbjct: 77 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 136
Query: 190 NRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKS 249
N VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NGGK ++ +
Sbjct: 137 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHN 196
Query: 250 KTT 252
++T
Sbjct: 197 EST 199
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 235 bits (600), Expect = 2e-62
Identities = 114/174 (65%), Positives = 134/174 (77%)
Query: 57 LCGKSLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGL 116
LCG + +PQLKGIVT+L+CRQG+YLQ +PDG++ GT +D+++ T FNLIPVGL
Sbjct: 52 LCGGRPARPDRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGL 111
Query: 117 RVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAW 176
RVV IQ K G Y+AMN EG LY S FT EC+FKE VFENYYV+Y+S LYRQ+ SGRAW
Sbjct: 112 RVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAW 171
Query: 177 FLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTP 230
+LGL+KEGQ MKGNRVKKTK AAHFLPK LEVAMY+EPSLH V E P P
Sbjct: 172 YLGLDKEGQVMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPEASPSSPPAP 225
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 125 bits (315), Expect = 3e-29
Identities = 58/137 (42%), Positives = 91/137 (66%), Gaps = 2/137 (1%)
Query: 73 LKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYI 130
LKGI+ R LYCR G++L++ P+G + GT+ D + + I + + +V+I+GV +GLY+
Sbjct: 57 LKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYL 116
Query: 131 AMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGN 190
MN +G LY SE T EC F+E EN+Y YSS LY+ ++GR +++ LNK+G +G
Sbjct: 117 GMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176
Query: 191 RVKKTKPAAHFLPKPLE 207
R K+ + HFLP+P++
Sbjct: 177 RTKRHQKFTHFLPRPVD 193
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 123 bits (309), Expect = 1e-28
Identities = 60/137 (43%), Positives = 90/137 (65%), Gaps = 2/137 (1%)
Query: 73 LKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYI 130
L GI+ R LYCR G++LQ+ PDG++ GT+ D + + I V + +V+I+GV +GLY+
Sbjct: 60 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL 119
Query: 131 AMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGN 190
MN +G LY SE T EC F+E EN+Y YSS +Y+ ++GR +F+ LNK+G G
Sbjct: 120 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA 179
Query: 191 RVKKTKPAAHFLPKPLE 207
R K+ + HFLP+P++
Sbjct: 180 RSKRHQKFTHFLPRPVD 196
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 121 bits (304), Expect = 5e-28
Identities = 58/144 (40%), Positives = 93/144 (64%), Gaps = 3/144 (2%)
Query: 67 NPTD-PQLKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQG 123
+PTD LKGI+ R LYCR G++L++ P+G + GT+ D + + I + + +++I+G
Sbjct: 49 SPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRG 108
Query: 124 VKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKE 183
V +GLY+ MN G LY S+ T EC F+E EN+Y Y+S LY+ +S R +++ LNK+
Sbjct: 109 VDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKD 168
Query: 184 GQAMKGNRVKKTKPAAHFLPKPLE 207
G +G R K+ + HFLP+P++
Sbjct: 169 GSPREGYRTKRHQKFTHFLPRPVD 192
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 98.2 bits (243), Expect = 6e-21
Identities = 51/129 (39%), Positives = 83/129 (64%), Gaps = 5/129 (3%)
Query: 80 LYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGY 137
LYCR G ++LQ++PDG ++G+ + + S L + V +V I+GV + ++AM+ +G
Sbjct: 91 LYCRVGIGFHLQIYPDGKVNGSHEANMLSVL-EIFAVSQGIVGIRGVFSNKFLAMSKKGK 149
Query: 138 LYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG--NRVKKT 195
L+ S FT +CKF+E EN Y Y+S ++R +++GR W++ LNK G+A +G RVK
Sbjct: 150 LHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQ 209
Query: 196 KPAAHFLPK 204
+ HFLP+
Sbjct: 210 HISTHFLPR 218
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 97.1 bits (240), Expect = 1e-20
Identities = 50/139 (35%), Positives = 85/139 (61%), Gaps = 11/139 (7%)
Query: 79 RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
+LYC Y+LQ+HP G ++G+ ++S S L + V + +VAI+G+ +G Y+AMN G L
Sbjct: 47 KLYCATKYHLQLHPSGRVNGSLENSAYSIL-EITAVEVGIVAIRGLFSGRYLAMNKRGRL 105
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLY----------RQQESGRAWFLGLNKEGQAMK 188
Y SE ++ EC+F E + E Y Y+S LY RQ + R W++ +N +G+ +
Sbjct: 106 YASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRR 165
Query: 189 GNRVKKTKPAAHFLPKPLE 207
G + ++T+ ++ FLP+ L+
Sbjct: 166 GFKTRRTQKSSLFLPRVLD 184
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 95.5 bits (236), Expect = 4e-20
Identities = 47/127 (37%), Positives = 76/127 (59%), Gaps = 2/127 (1%)
Query: 77 VTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 136
V RL+CR +YL++ G + GT++ N + + V + +VAI+GV++ Y+AMN EG
Sbjct: 66 VRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEG 125
Query: 137 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 196
LY + +C FKE + EN+Y Y+S + +G F+ LN++G ++G + KK +
Sbjct: 126 KLYAKKECNEDCNFKELILENHYNTYASA--KWTHNGGEMFVALNQKGIPVRGKKTKKEQ 183
Query: 197 PAAHFLP 203
AHFLP
Sbjct: 184 KTAHFLP 190
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 92.4 bits (228), Expect = 3e-19
Identities = 54/128 (42%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 79 RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 136
RLYC G ++LQ PDG + G D T +L L PV VV+I GV + ++AM+ +G
Sbjct: 85 RLYCNVGIGFHLQALPDGRIGGAHAD-TRDSLLELSPVERGVVSIFGVASRFFVAMSSKG 143
Query: 137 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 196
LY S FT EC FKE + N Y Y S Y F+ L+K G+ KGNRV T
Sbjct: 144 KLYGSPFFTDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTM 197
Query: 197 PAAHFLPK 204
HFLP+
Sbjct: 198 KVTHFLPR 205
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 87.0 bits (214), Expect = 1e-17
Identities = 47/135 (34%), Positives = 78/135 (57%), Gaps = 4/135 (2%)
Query: 71 PQLKGIVT--RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGL 128
P L+G V RL+ ++L++ P G + GT+ ++ + V + VV I+ V +G
Sbjct: 34 PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
Query: 129 YIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMK 188
Y+AMN G LY S L+T +C+F+E + EN + Y+S +R++ G+ FL L++ G
Sbjct: 94 YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
Query: 189 GNRVKKTKPAAHFLP 203
G R ++ +AHFLP
Sbjct: 152 GGRTRRYHLSAHFLP 166
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 87.0 bits (214), Expect = 1e-17
Identities = 47/128 (36%), Positives = 75/128 (58%), Gaps = 9/128 (7%)
Query: 79 RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 136
RLYC G ++LQ+ PDG + GT +++ S L + V VV++ GV++ L++AMN +G
Sbjct: 87 RLYCNVGIGFHLQVLPDGRISGTHEENPYS-LLEISTVERGVVSLFGVRSALFVAMNSKG 145
Query: 137 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 196
LY + F ECKF+E++ N Y Y S LY + ++ L+K G+ +G++V
Sbjct: 146 RLYATPSFQEECKFRETLLPNNYNAYESDLY------QGTYIALSKYGRVKRGSKVSPIM 199
Query: 197 PAAHFLPK 204
HFLP+
Sbjct: 200 TVTHFLPR 207
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 86.3 bits (212), Expect = 2e-17
Identities = 41/125 (32%), Positives = 74/125 (59%), Gaps = 2/125 (1%)
Query: 79 RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
+L+ Y+L++ +G + GTK ++ ++ + V + VVA++ + + Y+AMN +G L
Sbjct: 81 KLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKL 140
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 198
Y S+ F +CK KE + EN Y Y+S + Q +GR ++ LN +G +G + ++ +
Sbjct: 141 YGSKEFNNDCKLKERIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTS 198
Query: 199 AHFLP 203
AHFLP
Sbjct: 199 AHFLP 203
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 2e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 80 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 198
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 199 AHFLPKPL 206
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 2e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 80 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 198
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 199 AHFLPKPL 206
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 2e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 80 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 198
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 199 AHFLPKPL 206
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 2e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 80 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 138
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 139 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 198
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 199 AHFLPKPL 206
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 74.3 bits (181), Expect = 9e-14
Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 79 RLYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGY 137
RLYC+ G ++L++HPDG +DG ++ S L VV+I+GV Y+AM +G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGR 223
Query: 138 LYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKP 197
L S+ T EC F E + N Y Y S Y +W++ L + GQ G++ +
Sbjct: 224 LLASKCVTDECFFFERLESNNYNTYRSRKY------TSWYVALKRTGQYKLGSKTGPGQK 277
Query: 198 AAHFLP 203
A FLP
Sbjct: 278 AILFLP 283
>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
Length = 209
Score = 55.1 bits (131), Expect = 6e-08
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 26/162 (16%)
Query: 87 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 146
+L++ DG + G D S S L L + V+ I GVKT ++ +G LY S F P
Sbjct: 60 HLEIREDGTVGGAADQSPES-LLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
Query: 147 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA----AHF 201
E C F+E + E+ Y +Y S A L L+ + GN+ PA A F
Sbjct: 119 EACSFRELLLEDGYNVYQS---------EAHGLPLH-----LPGNKSPHRDPAPRGPARF 164
Query: 202 LPKP-LEVAMYREPSL-----HDVGETVPKPGVTPSKSTSAS 237
LP P L A+ P + DVG + P V PS+ S S
Sbjct: 165 LPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPS 206
>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
Length = 251
Score = 50.4 bits (119), Expect = 1e-06
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 83 RQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSE 142
R Y+LQ+H +G +DG + S L + V I GV + Y+ M+ G ++ S
Sbjct: 48 RNSYHLQIHKNGHVDGAPHQTIYSALM-IRSEDAGFVVITGVMSRRYLCMDFRGNIFGSH 106
Query: 143 LFTPE-CKFKESVFENYYVIYSSMLYR----QQESGRAWFLGLN 181
F PE C+F+ EN Y +Y S Y + RA+ G+N
Sbjct: 107 YFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMN 150
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 49.7 bits (117), Expect = 2e-06
Identities = 38/158 (24%), Positives = 74/158 (46%), Gaps = 13/158 (8%)
Query: 53 MLQCLCGKSLKKNKNPTDPQLKGIVT--RLYCR-QGYYLQMHPDGALDGTKDDSTN--ST 107
++ CL + +++ TD + ++ +LY R G ++Q+ + ++ +D
Sbjct: 16 LVLCLQAQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKL 75
Query: 108 LFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSML 166
+ G RV ++G +TGLYI MN +G L S +C F E V EN Y +
Sbjct: 76 IVETDTFGSRV-RVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAK 134
Query: 167 YRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPK 204
Y W++ ++G+ KG++ ++ + HF+ +
Sbjct: 135 Y------EGWYMAFTRKGRPRKGSKTRQHQREVHFMKR 166
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 119 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 150
Query: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPK 204
+ ++G+ KG++ ++ + HF+ +
Sbjct: 151 MAFTRKGRPRKGSKTRQHQREVHFMKR 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,372,518
Number of Sequences: 37866
Number of extensions: 482253
Number of successful extensions: 1061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1002
Number of HSP's gapped (non-prelim): 50
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.