Search of human proteins with 110681712

Search of human proteins with 110681712

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110681712 hepatoma derived growth factor-like 1 [Homo
sapiens]
         (251 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]     526   e-150
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]    249   2e-66
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...   213   2e-55
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...   213   2e-55
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...   147   7e-36
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...   147   7e-36
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho...   137   1e-32
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...   135   3e-32
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...   135   3e-32
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...   135   3e-32
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            52   4e-07
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]          50   2e-06
gi|33286446 opioid growth factor receptor [Homo sapiens]               45   6e-05
gi|7657575 sirtuin 1 isoform a [Homo sapiens]                          45   6e-05
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    45   8e-05
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       45   8e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             44   2e-04
gi|30795231 brain abundant, membrane attached signal protein 1 [...    44   2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              44   2e-04
gi|28274705 family with sequence similarity 9, member A [Homo sa...    44   2e-04
gi|153070260 myristoylated alanine-rich protein kinase C substra...    43   2e-04
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo...    43   2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     43   2e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    43   2e-04
gi|55956788 nucleolin [Homo sapiens]                                   42   4e-04
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    42   5e-04
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    42   5e-04
gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Ho...    42   5e-04
gi|217035154 RCSD domain containing 1 [Homo sapiens]                   42   7e-04
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    41   9e-04

>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
          Length = 251

 Score =  526 bits (1354), Expect = e-150
 Identities = 251/251 (100%), Positives = 251/251 (100%)

Query: 1   MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYK 60
           MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYK
Sbjct: 1   MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFGTHETAFLSPKRLFPYK 60

Query: 61  ECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPT 120
           ECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPT
Sbjct: 61  ECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPT 120

Query: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
           HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE
Sbjct: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180

Query: 181 RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA 240
           RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA
Sbjct: 181 RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA 240

Query: 241 EAPGGGDRDSL 251
           EAPGGGDRDSL
Sbjct: 241 EAPGGGDRDSL 251


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score =  249 bits (635), Expect = 2e-66
 Identities = 141/251 (56%), Positives = 161/251 (64%), Gaps = 28/251 (11%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQP------NRYQVFFFGTHETAFLSPKRLFPYKEC 62
           YK GDLVFAK+KGY HWPARI+ M +       N+YQVFFFGTHETAFL PK LFPY+E 
Sbjct: 10  YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122
           KEKFGKPNKR+GFS GLWEIENNPTV+AS    + +K   + P PEPEAAEGD DK  +A
Sbjct: 70  KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNA 129

Query: 123 GGGGDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
            G  DE GK   D+P +E  EKG LKR AGD  ED+PKRPKEA   + EE E        
Sbjct: 130 EGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE-------- 181

Query: 181 RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA 240
                  A  ++ E P  + VE  S PSEPG    PPQ EEEE  EEE A +E      A
Sbjct: 182 -------AATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKE-----DA 229

Query: 241 EAPGGGDRDSL 251
           EAPG  D +SL
Sbjct: 230 EAPGIRDHESL 240


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score =  213 bits (541), Expect = 2e-55
 Identities = 122/218 (55%), Positives = 139/218 (63%), Gaps = 22/218 (10%)

Query: 36  NRYQVFFFGTHETAFLSPKRLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPL 95
           N+YQVFFFGTHETAFL PK LFPY+E KEKFGKPNKR+GFS GLWEIENNPTV+AS    
Sbjct: 36  NKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQS 95

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEE--EKGPLKRSAGDPP 153
           + +K   + P PEPEAAEGD DK  +A G  DE GK   D+P +E  EKG LKR AGD  
Sbjct: 96  SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 155

Query: 154 EDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLV 213
           ED+PKRPKEA   + EE E               A  ++ E P  + VE  S PSEPG  
Sbjct: 156 EDSPKRPKEAENPEGEEKE---------------AATLEVERPLPMEVEKNSTPSEPGSG 200

Query: 214 CEPPQPEEEELREEEVADEEASQEWHAEAPGGGDRDSL 251
             PPQ EEEE  EEE A +E      AEAPG  D +SL
Sbjct: 201 RGPPQEEEEEEDEEEEATKE-----DAEAPGIRDHESL 233


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
           sapiens]
          Length = 256

 Score =  213 bits (541), Expect = 2e-55
 Identities = 122/218 (55%), Positives = 139/218 (63%), Gaps = 22/218 (10%)

Query: 36  NRYQVFFFGTHETAFLSPKRLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPL 95
           N+YQVFFFGTHETAFL PK LFPY+E KEKFGKPNKR+GFS GLWEIENNPTV+AS    
Sbjct: 59  NKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQS 118

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEE--EKGPLKRSAGDPP 153
           + +K   + P PEPEAAEGD DK  +A G  DE GK   D+P +E  EKG LKR AGD  
Sbjct: 119 SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 178

Query: 154 EDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLV 213
           ED+PKRPKEA   + EE E               A  ++ E P  + VE  S PSEPG  
Sbjct: 179 EDSPKRPKEAENPEGEEKE---------------AATLEVERPLPMEVEKNSTPSEPGSG 223

Query: 214 CEPPQPEEEELREEEVADEEASQEWHAEAPGGGDRDSL 251
             PPQ EEEE  EEE A +E      AEAPG  D +SL
Sbjct: 224 RGPPQEEEEEEDEEEEATKE-----DAEAPGIRDHESL 256


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score =  147 bits (372), Expect = 7e-36
 Identities = 83/199 (41%), Positives = 110/199 (55%), Gaps = 27/199 (13%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           +K GDLVFAK+KGY HWPARI+ +        PN+Y +FFFGTHETAFL PK LFPY +C
Sbjct: 5   FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEG------DE 116
           K+K+GKPNKR+GF+ GLWEI+NNP    S  P  S   S D   PE   A+G      DE
Sbjct: 65  KDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVS---SSDSEAPEANPADGSDADEDDE 121

Query: 117 DKPTHA-----GGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQE--- 168
           D+   A          +  + D D     +   LKR          KR ++A+ D +   
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181

Query: 169 ----EEAEAERAAEAERAA 183
               EE  +E ++E+E+ +
Sbjct: 182 VSPSEEENSESSSESEKTS 200



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 9/79 (11%)

Query: 110 EAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEE 169
           E A+  E +    G  GDEL   +DD+P  +++G   R  G P         ++ P+ E 
Sbjct: 355 ERADRGEAERGSGGSSGDEL--REDDEPV-KKRGRKGRGRGPPSS------SDSEPEAEL 405

Query: 170 EAEAERAAEAERAAAAAAA 188
           E EA+++A+  ++++   A
Sbjct: 406 EREAKKSAKKPQSSSTEPA 424


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score =  147 bits (372), Expect = 7e-36
 Identities = 83/199 (41%), Positives = 110/199 (55%), Gaps = 27/199 (13%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           +K GDLVFAK+KGY HWPARI+ +        PN+Y +FFFGTHETAFL PK LFPY +C
Sbjct: 5   FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEG------DE 116
           K+K+GKPNKR+GF+ GLWEI+NNP    S  P  S   S D   PE   A+G      DE
Sbjct: 65  KDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVS---SSDSEAPEANPADGSDADEDDE 121

Query: 117 DKPTHA-----GGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQE--- 168
           D+   A          +  + D D     +   LKR          KR ++A+ D +   
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181

Query: 169 ----EEAEAERAAEAERAA 183
               EE  +E ++E+E+ +
Sbjct: 182 VSPSEEENSESSSESEKTS 200



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 9/79 (11%)

Query: 110 EAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEE 169
           E A+  E +    G  GDEL   +DD+P  +++G   R  G P         ++ P+ E 
Sbjct: 355 ERADRGEAERGSGGSSGDEL--REDDEPV-KKRGRKGRGRGPPSS------SDSEPEAEL 405

Query: 170 EAEAERAAEAERAAAAAAA 188
           E EA+++A+  ++++   A
Sbjct: 406 EREAKKSAKKPQSSSTEPA 424


>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
           sapiens]
          Length = 203

 Score =  137 bits (344), Expect = 1e-32
 Identities = 74/180 (41%), Positives = 105/180 (58%), Gaps = 15/180 (8%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           YK+GDLVFAK+KGY HWPARI+ + +       N+Y +FFFGTHETAFL PK LFPYKE 
Sbjct: 9   YKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEY 68

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122
           K+KFGK NKR+GF+ GLWEIENNP V+ +      ++ S +         EG       +
Sbjct: 69  KDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSE------TEGEGGNTADASS 122

Query: 123 GGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEE--AEAERAAEAE 180
              GD + + D     + EK   KR      + + K+ +++  D++++   E E  + +E
Sbjct: 123 EEEGDRV-EEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSE 181


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  135 bits (340), Expect = 3e-32
 Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 27/238 (11%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           +K GDL+FAK+KGY HWPAR++ +         N+  +FFFGTHETAFL PK +FPY E 
Sbjct: 5   FKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSEN 64

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEK--GSGDGPWPEPEAAEGDEDKPT 120
           KEK+GKPNKR+GF+ GLWEI+NNP V+ S    A+++   S D    E E +   ED   
Sbjct: 65  KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDH 124

Query: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
                 +++ K  D    +  +   KR A                  E++ E E A    
Sbjct: 125 EEKASNEDVTKAVDITTPKAARRGRKRKA------------------EKQVETEEAGVVT 166

Query: 181 RAAAAAAATAVDEES-PFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
            A A+       +   P    V+       P +V +P   E + + EE+ + ++  +E
Sbjct: 167 TATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEE 224



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 113 EGDEDKPTHAGGGGDELGKPDDDKPTEE-EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA 171
           +G E+K        DE G+ ++DKP +E +K   K+      ++  K    +  D EEE 
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEG 279

Query: 172 EAERAAEAERAAAAAAATA 190
           + ++  E +R       TA
Sbjct: 280 D-DQEGEKKRKGGRNFQTA 297


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score =  135 bits (340), Expect = 3e-32
 Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 27/238 (11%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           +K GDL+FAK+KGY HWPAR++ +         N+  +FFFGTHETAFL PK +FPY E 
Sbjct: 5   FKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSEN 64

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEK--GSGDGPWPEPEAAEGDEDKPT 120
           KEK+GKPNKR+GF+ GLWEI+NNP V+ S    A+++   S D    E E +   ED   
Sbjct: 65  KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDH 124

Query: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
                 +++ K  D    +  +   KR A                  E++ E E A    
Sbjct: 125 EEKASNEDVTKAVDITTPKAARRGRKRKA------------------EKQVETEEAGVVT 166

Query: 181 RAAAAAAATAVDEES-PFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
            A A+       +   P    V+       P +V +P   E + + EE+ + ++  +E
Sbjct: 167 TATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEE 224



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 113 EGDEDKPTHAGGGGDELGKPDDDKPTEE-EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA 171
           +G E+K        DE G+ ++DKP +E +K   K+      ++  K    +  D EEE 
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEG 279

Query: 172 EAERAAEAERAAAAAAATA 190
           + ++  E +R       TA
Sbjct: 280 D-DQEGEKKRKGGRNFQTA 297


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  135 bits (340), Expect = 3e-32
 Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 27/238 (11%)

Query: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
           +K GDL+FAK+KGY HWPAR++ +         N+  +FFFGTHETAFL PK +FPY E 
Sbjct: 5   FKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSEN 64

Query: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEK--GSGDGPWPEPEAAEGDEDKPT 120
           KEK+GKPNKR+GF+ GLWEI+NNP V+ S    A+++   S D    E E +   ED   
Sbjct: 65  KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDH 124

Query: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
                 +++ K  D    +  +   KR A                  E++ E E A    
Sbjct: 125 EEKASNEDVTKAVDITTPKAARRGRKRKA------------------EKQVETEEAGVVT 166

Query: 181 RAAAAAAATAVDEES-PFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
            A A+       +   P    V+       P +V +P   E + + EE+ + ++  +E
Sbjct: 167 TATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEE 224



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 113 EGDEDKPTHAGGGGDELGKPDDDKPTEE-EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA 171
           +G E+K        DE G+ ++DKP +E +K   K+      ++  K    +  D EEE 
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEG 279

Query: 172 EAERAAEAERAAAAAAATA 190
           + ++  E +R       TA
Sbjct: 280 D-DQEGEKKRKGGRNFQTA 297


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 20/185 (10%)

Query: 86  PTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPT------HAGGGGDELGKPDDDKPTE 139
           P V A       E G+  G    PE +EG E+ P        AGGGG + G   + + T 
Sbjct: 18  PEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTR 77

Query: 140 EEKGPLKRSAGDPP-EDAPKRPKEAAPDQEEE-------AEAERAAEAERAAAAAAATAV 191
              G  +   G P   + P+  +E +  Q+ E       A+ E   EA+R    +AA   
Sbjct: 78  GAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPER 137

Query: 192 DEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWH------AEAPGG 245
            EE+     V  GSA  E G   +   P  + +  E  A +    E        AE P G
Sbjct: 138 QEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAG 197

Query: 246 GDRDS 250
              D+
Sbjct: 198 DSVDA 202



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/163 (26%), Positives = 57/163 (34%), Gaps = 13/163 (7%)

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEE---KGPLKRSAGDP 152
           A  +G   GP   PE      ++P   G  G E   P+  +  EE       +K + G  
Sbjct: 5   AEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGG 64

Query: 153 PEDAPKRPKEAAPDQEEEAEAERAAE-----AERAAAAAAATAVDEESPFLVA--VENGS 205
           P+  P+           E EAE  A       +     + A  V+  SP   A     G 
Sbjct: 65  PDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE 124

Query: 206 APSEPGLVCEPPQPEEEELR---EEEVADEEASQEWHAEAPGG 245
           A  EP     P + EE E R    E  A  EA     AE P G
Sbjct: 125 AQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLG 167



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 10/102 (9%)

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPED 155
           A+E+    G     EAA GD      A  G D +G     +P E+E+   +RS   P E+
Sbjct: 330 AAEEAEVPGVKGSEEAAPGD----ARADAGEDRVGDGPQQEPGEDEE-RRERSPEGPREE 384

Query: 156 APKRPKEAAPDQEEEAEAER-AAEAERAAAAAAATAVDEESP 196
                +E +PD     EA R AAE E    A  +  + EE P
Sbjct: 385 EAAGGEEESPDSSPHGEASRGAAEPE----AQLSNHLAEEGP 422



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 41/164 (25%), Positives = 53/164 (32%), Gaps = 12/164 (7%)

Query: 96  ASEKGSGDGPWPEPEAAEGDE----DKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGD 151
           A +    +GP  +   AEG      D     G   D  G   D    E   G     AGD
Sbjct: 196 AGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGD-SVEAGD 254

Query: 152 PPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEE-------SPFLVAVENG 204
           P  D  +    A    E E  A  + +AE  A  A   + + +       SP   A+E  
Sbjct: 255 PAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVA 314

Query: 205 SAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAPGGGDR 248
           +  S      E      EE     V   E +    A A  G DR
Sbjct: 315 AGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDR 358


>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 18/169 (10%)

Query: 12  GDLVFAKLKGYAHWPARI----EHMTQPNRYQVFF---FGTHETAFLSPKRLFPYKECKE 64
           GDLV+ KL  Y  WP +I    + + +P   + FF   FGT + A++  ++L PY   KE
Sbjct: 9   GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68

Query: 65  KFGKPNKRRGFSAGLWEIEN-----NPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKP 119
           +  K NK + F   +  +E          Q S    + +K   +          GDE + 
Sbjct: 69  EMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRK 128

Query: 120 THAGGG------GDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKE 162
                G      G+   +          K PLKR+    P    + PK+
Sbjct: 129 LSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKD 177


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 86  PTVQASDCPLASEKGSGDGPWP------EPEAAEGDEDKPTHAGGGGDELGKPDDDKPTE 139
           P   A D P A       GP P      EP  +  +   P  AG  GDE  +   + P  
Sbjct: 566 PAGPAGDEP-AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 624

Query: 140 EEKGPLKRSAGDPPEDAPKR---PKEAAPDQEEEAEAERAAEAERAAAAAAA 188
              GP    AGD P ++P     P  A P ++E A+A  AAE + A   ++A
Sbjct: 625 RPAGP----AGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 37/148 (25%), Positives = 52/148 (35%), Gaps = 12/148 (8%)

Query: 85  NPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDK--------PTHAGGGGDELGKPDDDK 136
           +P   A D P  S     + P P P    GDE          P  AG  GDE  +   + 
Sbjct: 525 SPAGPAGDEPAESPS---ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 581

Query: 137 PTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESP 196
           P     GP +    + P + P  P+ A P  +E AE+       R A  A     +  S 
Sbjct: 582 PGPSPAGPTRDEPAESPSETP-GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 640

Query: 197 FLVAVENGSAPSEPGLVCEPPQPEEEEL 224
                  G    EP    E  + ++ E+
Sbjct: 641 TPGPSPAGPTRDEPAKAGEAAELQDAEV 668



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 32/205 (15%)

Query: 62  CKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAA-EGDEDKPT 120
           CK  +G  +K R F        + P        +  E   GD   P+ EA+ +G    P 
Sbjct: 282 CKFVWGPQDKLRRFKPS-----SLPHPLEGSRKVEEEGSPGD---PDHEASTQGRTCGPE 333

Query: 121 HAGGGG--DELGKPDDDKPTEEEKGPLKRSAGD-------------PPEDAPKRPKEAAP 165
           H+ GGG  DE  +P   +P  ++ GPL+RS GD              P+++ KR  E + 
Sbjct: 334 HSKGGGRVDEGPQPRSVEP--QDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSR 391

Query: 166 DQEEEAE--AERAAEAERAAAAAAATAVDEESPFLVAVE-NGSAPSEPGLVCEPPQPEE- 221
            ++   E   + A+E E+ A      A+ + S      E  G  P E    C  P     
Sbjct: 392 REQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARV 451

Query: 222 -EELREEEVADEEASQEWHAEAPGG 245
            +++R+    DE A     A A GG
Sbjct: 452 ADKVRKRRKVDEGAGDS-AAVASGG 475



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 10/150 (6%)

Query: 104 GPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKR---P 160
           GP      +  +   P+ AG  GDE  +   + P     GP    AGD P ++P     P
Sbjct: 509 GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGP----AGDEPAESPSETPGP 564

Query: 161 KEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPG-LVCEPPQP 219
           + A P  +E AE+         A        +  S        G A  EP     E P P
Sbjct: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 624

Query: 220 EEEELREEEVADEEASQEWHAEAPGGGDRD 249
                  +E A  E+  E    +P G  RD
Sbjct: 625 RPAGPAGDEPA--ESPSETPGPSPAGPTRD 652



 Score = 32.0 bits (71), Expect = 0.52
 Identities = 36/138 (26%), Positives = 45/138 (32%), Gaps = 6/138 (4%)

Query: 111 AAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEE 170
           A  G      H   G  E G  +D   TE   GP + + G P E     P  A P  +E 
Sbjct: 480 ALAGSPAPSGHPKAGHSENGVEED---TEGRTGPKEGTPGSPSE--TPGPSPAGPAGDEP 534

Query: 171 AEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPG-LVCEPPQPEEEELREEEV 229
           AE+       R A  A     +  S        G A  EP     E P P       +E 
Sbjct: 535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594

Query: 230 ADEEASQEWHAEAPGGGD 247
           A+  +       A   GD
Sbjct: 595 AESPSETPGPRPAGPAGD 612


>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
          Length = 747

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 47/157 (29%), Positives = 65/157 (41%), Gaps = 11/157 (7%)

Query: 95  LASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPE 154
           +A E      P   P AA  D +            G+P   +P  +  G L+RS G+P  
Sbjct: 1   MADEAALALQPGGSPSAAGADRE------AASSPAGEPLRKRPRRDGPG-LERSPGEPGG 53

Query: 155 DAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVC 214
            AP+R   AA      A A  AA    A A AAA   ++E+    A   G   + PGL  
Sbjct: 54  AAPEREVPAAARGCPGAAA--AALWREAEAEAAAAGGEQEAQATAAA--GEGDNGPGLQG 109

Query: 215 EPPQPEEEELREEEVADEEASQEWHAEAPGGGDRDSL 251
              +P   +   +E  D+E  +E  A A   G RD+L
Sbjct: 110 PSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNL 146


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 48/183 (26%), Positives = 77/183 (42%), Gaps = 16/183 (8%)

Query: 71  KRRGFSAGLWEIENNPTVQ-ASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDEL 129
           +RRG  +   +++    +Q A D  +  ++  G G  P    A   E +P  A GGG   
Sbjct: 16  QRRGLDSRGLKVDLAQRLQEALDAEMLEDEAGGGGAGPG--GACKAEPRPVAASGGGPGG 73

Query: 130 GKPDDDKPTEEEKGPLKRSAGD--PPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAA 187
            + +D++  EE++  L     +  PP  A  +  +  P+  E A  E AAE + +   A 
Sbjct: 74  DEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAE 133

Query: 188 ATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAPGGGD 247
           ATA           E G    E     EP +   +E    EV  ++A++E       G D
Sbjct: 134 ATA--GSGGVNGGEEQGLGKREED---EPEERSGDETPGSEVPGDKAAEE------QGDD 182

Query: 248 RDS 250
           +DS
Sbjct: 183 QDS 185



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 45/151 (29%), Positives = 61/151 (40%), Gaps = 24/151 (15%)

Query: 94  PLASEKGSGDGPWPEPE-------AAEGD-EDKPTHA----GG--GGDE--LGKPDDDKP 137
           P A   G    P PEP        AAE D  +KP  A    GG  GG+E  LGK ++D+P
Sbjct: 98  PPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEP 157

Query: 138 TEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPF 197
             EE+   +    + P D  K  +E   DQ+ E      ++ ER          DE    
Sbjct: 158 --EERSGDETPGSEVPGD--KAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGRA 213

Query: 198 LVAVENGSAPSEPGLVCEPPQPEEEELREEE 228
                  +  S      + P P EEE ++EE
Sbjct: 214 YYEFREEAYHSR----SKSPLPPEEEAKDEE 240


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 48/171 (28%), Positives = 75/171 (43%), Gaps = 35/171 (20%)

Query: 83   ENNPTVQASDCP----LASEKGSGDGPWPEPEAAEGD----EDKPTHAGGGGDELGKPDD 134
            E  P  +A D P    L SE  +G       E  E +    ++KP  AG   +E G+ + 
Sbjct: 4871 EKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET 4930

Query: 135  DK-----PTEEEKGPLKRSAGDPPED----APKRPKEAAPDQEEEAEAERAAEAERAAAA 185
            D+     P E E+GP +    +  E+    A  +  +AA   EE +E ++ +  E+   A
Sbjct: 4931 DQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEA 4990

Query: 186  AAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQ 236
                  DEE       ENG  P++ G      QP+EEE RE+   +E+  +
Sbjct: 4991 ------DEEGG-----ENG--PADQGF-----QPQEEEEREDSDTEEQVPE 5023



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 11/137 (8%)

Query: 107  PEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPD 166
            PEPEA +  +D    +    D+ G  D D    EE+ PL+    + PE+A    +E    
Sbjct: 4874 PEPEALDLPDDLNLDSE---DKNGGEDTDNEEGEEENPLEIK--EKPEEAGHEAEERGET 4928

Query: 167  QEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELRE 226
            + ++ E++   E E   +       +EE      ++ G+   +      P +  EE+ + 
Sbjct: 4929 ETDQNESQSPQEPEEGPSEDDKAEGEEE------MDTGADDQDGDAAQHPEEHSEEQQQS 4982

Query: 227  EEVADEEASQEWHAEAP 243
             E  D+EA +E     P
Sbjct: 4983 VEEKDKEADEEGGENGP 4999



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 8/131 (6%)

Query: 108  EPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGD-PPEDAPKRPKEAAPD 166
            E  A E  ED       G  E  + DD+K ++ E G L +  GD   E+A K  +    D
Sbjct: 4723 EDNAIEMSEDFDGKMHDGELEEQEEDDEK-SDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781

Query: 167  QEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELRE 226
             +EE + E     E          +DEE   LVA ++           +  Q +++E +E
Sbjct: 4782 DDEEEDEEE----EDNKTEETGPGMDEEDSELVAKDDNLDSGNSNK--DKSQQDKKEEKE 4835

Query: 227  EEVADEEASQE 237
            E  AD+    E
Sbjct: 4836 EAEADDGGQGE 4846



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 30/133 (22%), Positives = 50/133 (37%), Gaps = 8/133 (6%)

Query: 63   KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122
            K K G+ +  R         ++N  V      + ++  +  GP  +P+A   D D   H 
Sbjct: 5098 KRKPGQADNERSMG------DHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHI 5151

Query: 123  GGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEE--EAEAERAAEAE 180
              G D       D  ++E++   K S  D  E+  +       +QEE   A+ E+    E
Sbjct: 5152 KQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEE 5211

Query: 181  RAAAAAAATAVDE 193
              +   A    DE
Sbjct: 5212 IKSGTTAPLGFDE 5224



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 40/171 (23%), Positives = 62/171 (36%), Gaps = 28/171 (16%)

Query: 60   KECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKP 119
            KE  E+ G   + RG        E       S  P   E+G       E + AEG+E+  
Sbjct: 4912 KEKPEEAGHEAEERG--------ETETDQNESQSPQEPEEGPS-----EDDKAEGEEEMD 4958

Query: 120  THAGG-GGDELGKPDDDKPTEEEKGPLKRSAGDP------PEDAPKRPKEAAPDQEEEAE 172
            T A    GD    P++    +++    K    D       P D   +P+E    ++ + E
Sbjct: 4959 TGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTE 5018

Query: 173  AERAAEAERAA-AAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEE 222
             +     ER   A+   T V+        ++N  A    G   E  Q +EE
Sbjct: 5019 EQVPEALERKEHASCGQTGVEN-------MQNTQAMELAGAAPEKEQGKEE 5062


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 42/143 (29%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 86   PTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPL 145
            PT  A+  P   E  S     P PE    +   P  A    +E   P    PT EE  P 
Sbjct: 1078 PTSPAAAVPTPEEPTSPAAAVPTPE----EPTSPAAAVPTPEEPASPAAAVPTPEE--PA 1131

Query: 146  KRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEA--ERAAAAAAATAVDEESPFLVAVEN 203
              +A  P  + P  P  A P  EE A A  A     E A+ AAA     E + F   V  
Sbjct: 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT 1191

Query: 204  GSAPSEPGLVCEPPQPEEEELRE 226
               P+ P      P      L E
Sbjct: 1192 LEEPTSPAASVPTPAAMVATLEE 1214



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 41/144 (28%), Positives = 52/144 (36%), Gaps = 19/144 (13%)

Query: 94   PLASEKGSGDGPWPEPEAAEGDEDKPTHAG--GGGDELGKPDDDKPTEEE---------- 141
            P+  E G+ +GP          E+  T A      +E   P    PT EE          
Sbjct: 963  PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT 1022

Query: 142  -KGPLKRSAGDPPEDAPKRPKEAAPDQEE---EAEAERAAEAERAAAAAAATAVDEESPF 197
             + P   +A  PP + P  P  A P  EE    A A    E   + AAA  T  +  SP 
Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP- 1081

Query: 198  LVAVENGSAPSEPGLVCEPPQPEE 221
              AV     P+ P      P PEE
Sbjct: 1082 AAAVPTPEEPTSPAAAV--PTPEE 1103



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/160 (28%), Positives = 55/160 (34%), Gaps = 10/160 (6%)

Query: 86   PTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPL 145
            PT  A+  P   E  S     P PE    +   P  A    +E   P    PT EE  P 
Sbjct: 1026 PTSPAAAVPPPEEPTSPAAAVPTPE----EPTSPAAAVPTPEEPTSPAAAVPTPEE--PT 1079

Query: 146  KRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEA--ERAAAAAAATAVDEESPFLVAVEN 203
              +A  P  + P  P  A P  EE      A     E A+ AAA    +E +    AV  
Sbjct: 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139

Query: 204  GSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP 243
               P+ P      P PEE       V   E S    A  P
Sbjct: 1140 PEEPAFPAPAV--PTPEESASAAVAVPTPEESASPAAAVP 1177



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 29/113 (25%), Positives = 41/113 (36%), Gaps = 4/113 (3%)

Query: 108  EPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQ 167
            EP +       P       +E   P    PT EE   L  +  +P E  P  P  A P  
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE--PTSPAAAVPTL 1251

Query: 168  EEEAEAERA--AEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQ 218
            EE   +  A     E ++ AA+    +E +    AV N   P+ P      P+
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 7/120 (5%)

Query: 109  PEAAEGDEDKPTHAGGG---GDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAP 165
            P AA    ++PT +       +EL  P    PT EE  P   +A     + P  P  A P
Sbjct: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEE--PASPAAAVSNLEEPASPAAAVP 1301

Query: 166  DQEEEAEAERAAEAERAAA--AAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEE 223
              E  A    +       A  AAA   ++E SP  V     SA ++   + E   P  EE
Sbjct: 1302 TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEE 1361


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/159 (31%), Positives = 72/159 (45%), Gaps = 23/159 (14%)

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPED 155
           A+ +  G     EP+AA     +P  A  G +   KPD D   + E+   ++ A    E+
Sbjct: 29  AATEEEGTPKESEPQAAA----EPAEAKEGKE---KPDQDAEGKAEEKEGEKDAAAAKEE 81

Query: 156 APKRPKEAAPDQEE---EAEAER--AAEAERAAAAAAATAVDEESPFLVAVENGSAPSEP 210
           APK    A P++ E   EA+AE   A E E+AA   AA     E+P   A E  +AP+E 
Sbjct: 82  APK----AEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGG---EAP--KAAEAAAAPAES 132

Query: 211 GLVC--EPPQPEEEELREEEVADEEASQEWHAEAPGGGD 247
                 E P  EE E ++ E     A+QE  ++     D
Sbjct: 133 AAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASD 171



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 42/136 (30%), Positives = 55/136 (40%), Gaps = 21/136 (15%)

Query: 127 DELGKPDDDKP----TEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERA 182
           DE  K  D K     TEEE  P +       E A  +  +  PDQ+ E +AE   E E+ 
Sbjct: 16  DEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEE-KEGEKD 74

Query: 183 AAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQ-PEEEELR-------EEEVADEEA 234
           AAAA      EE+P     E            EPP+ PE+E+         E   A E A
Sbjct: 75  AAAA-----KEEAP---KAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAA 126

Query: 235 SQEWHAEAPGGGDRDS 250
           +    + AP  G+  S
Sbjct: 127 AAPAESAAPAAGEEPS 142



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 40/163 (24%), Positives = 61/163 (37%), Gaps = 28/163 (17%)

Query: 61  ECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEK---GSGDGPWPEPEAAEGDED 117
           E KE   KP++     A   E E +      + P A  +   G+ +     P+A E ++ 
Sbjct: 50  EAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQA 109

Query: 118 KPTHAGGG------------GDELGKPDDDKPTEEEKGPLK------------RSAGDPP 153
            P  A GG             +       ++P++EE  P K            +S G P 
Sbjct: 110 APGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPA 169

Query: 154 EDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESP 196
            D+     EAAP  +E   A  A  +   A   AA+A +E  P
Sbjct: 170 SDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASA-EEPKP 211



 Score = 32.0 bits (71), Expect = 0.52
 Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 89  QASDCPLASEKGSGDGPWPEPEAAEGDED----KPTHAGGGGDELGKPDDDKPTEEEKGP 144
           +  + P    +G  +    E +AA   E+    +P    G  +   +P    P +E+  P
Sbjct: 53  EGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPK-APEQEQAAP 111

Query: 145 LKRSAGDPPE--DAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVE 202
              + G+ P+  +A   P E+A     E  ++   E ++  A AA  A + +S    A +
Sbjct: 112 GPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASD 171

Query: 203 NGSAPSE 209
           +    SE
Sbjct: 172 SKPGSSE 178


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 53/185 (28%), Positives = 69/185 (37%), Gaps = 23/185 (12%)

Query: 67   GKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGG 126
            G+ +   G  A   E E  P  +  + P A     GD    E EA    ED       G 
Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAE----GDAQEAEGEAQPESEDVEAPEAEGE 1882

Query: 127  DELGKPDDDKPTEE-EKGPLKRSAGDPPEDAPKRPKEAAPDQEE----EAEAERAAEAER 181
             +    D + P  E E  P    A     +AP+  KEA P+ E     E E E   E+E 
Sbjct: 1883 AQPESEDVETPEAEWEVQPESEGA-----EAPEAEKEAQPETESVEALETEGEDEPESEG 1937

Query: 182  AAAAAAATAVDE----ESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
            A A  A  A  E      P    +E+  A  E       P+ E+ E  E EV  +EA  E
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEEE-----AQPESEDVEALEVEVETQEAEGE 1992

Query: 238  WHAEA 242
               E+
Sbjct: 1993 AQPES 1997



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 11/172 (6%)

Query: 88   VQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKR 147
            V+  +    ++  S D   PE E    + ++       G E     + +  +E +G  ++
Sbjct: 1984 VETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK 2043

Query: 148  SAGDP-PE----DAPKRPKEA--APDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVA 200
            + GD  PE    +AP+  +EA  A  + +EAE E   E+E   A  A      ES  + A
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEA 2103

Query: 201  VE-NGSAPSEPGLVCEPPQPEEEELREEE-VADEEASQEWHAEAPGGGDRDS 250
             E  G A    G+  E P+ E E   E E +   EA  E   E+ G   +D+
Sbjct: 2104 PEAEGEAQKAEGI--EAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDA 2153



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 36/134 (26%), Positives = 51/134 (38%)

Query: 111  AAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEE 170
            AA GD+D     G  G E  + + +   E E      + GD  E   +   E+   +  E
Sbjct: 1819 AAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE 1878

Query: 171  AEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVA 230
            AE E   E+E      A   V  ES    A E            E  + E E+  E E A
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA 1938

Query: 231  DEEASQEWHAEAPG 244
            + + ++E   EA G
Sbjct: 1939 EAQEAEEAAQEAEG 1952



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/191 (26%), Positives = 71/191 (37%), Gaps = 19/191 (9%)

Query: 61   ECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPT 120
            E  E  G+  K  G  A   E E  P  +  + P A  +   +    E + AEG E +P 
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG-EAQPE 2160

Query: 121  HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQE--EEAEAERAAE 178
              G    E          EEE  P          +AP+   EA P+ E  E  EAE  A+
Sbjct: 2161 SEGIEAQE---------AEEEAQPELEGV-----EAPEAEGEAQPESEGIEAPEAEGEAQ 2206

Query: 179  AERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCE-PPQPEEEELREEEVADEEASQE 237
             E      A  A +E  P    VE   A  E     E   Q E++   +  + D ++ + 
Sbjct: 2207 PE-LEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEA 2265

Query: 238  WHAEAPGGGDR 248
              + +P   DR
Sbjct: 2266 SESSSPVPEDR 2276



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 49/202 (24%), Positives = 72/202 (35%), Gaps = 36/202 (17%)

Query: 60   KECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGS-GDGPWPEPEAAEGDEDK 118
            +E +E  G+  K  G        +  P     + P A E+    +G   E E     E +
Sbjct: 2032 EEAQEVEGETQKTEG--------DAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083

Query: 119  PTHAGGGGDELGKPDDDKPTEEEKGPLKRSAG-DPPE------------DAPKRPKEAAP 165
               A     E     +     E +G  +++ G + PE            +AP+   EA P
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQP 2143

Query: 166  DQE----EEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEE 221
            + E    ++AE E   E+E      A  A +E  P L  VE   A  E        QPE 
Sbjct: 2144 ESEGVEAQDAEGEAQPESE---GIEAQEAEEEAQPELEGVEAPEAEGE-------AQPES 2193

Query: 222  EELREEEVADEEASQEWHAEAP 243
            E +   E   E   +    EAP
Sbjct: 2194 EGIEAPEAEGEAQPELEGVEAP 2215



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 18/162 (11%)

Query: 80   WEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTE 139
            WE++  P  + ++ P A ++   +    E    EG ED+P   G    E      ++  +
Sbjct: 1897 WEVQ--PESEGAEAPEAEKEAQPETESVEALETEG-EDEPESEGAEAQEA-----EEAAQ 1948

Query: 140  EEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLV 199
            E +G  +      PE      +EA    EEEA+ E               A  E  P   
Sbjct: 1949 EAEGQTQ------PESEVIESQEA----EEEAQPESEDVEALEVEVETQEAEGEAQPESE 1998

Query: 200  AVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAE 241
             VE   A  E     E  QPE + +  +  ++ E +QE   E
Sbjct: 1999 DVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGE 2040



 Score = 32.0 bits (71), Expect = 0.52
 Identities = 26/115 (22%), Positives = 42/115 (36%), Gaps = 7/115 (6%)

Query: 74   GFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPD 133
            G  A   E E  P ++  + P A E+   +    E   AEG+    +     G++ G P 
Sbjct: 2195 GIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQ 2254

Query: 134  ---DDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAA 185
                D  +EE       S+   PED P  P     D   +    +   +   A++
Sbjct: 2255 VSLGDGQSEE----ASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASS 2305



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 29/131 (22%), Positives = 44/131 (33%), Gaps = 13/131 (9%)

Query: 96   ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPED 155
            A E+G  +   PE  +  G E          D  G  +DD   EEE G    SA   P +
Sbjct: 1389 ALEEGLKEEGLPEEGSVHGQE---LSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAE 1445

Query: 156  APKRPKE----------AAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGS 205
              + P E          +A +++  ++ E   E    A          +     A  + S
Sbjct: 1446 GTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505

Query: 206  APSEPGLVCEP 216
                  L C+P
Sbjct: 1506 VACSAALDCDP 1516


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 34/82 (41%), Positives = 42/82 (51%), Gaps = 13/82 (15%)

Query: 166 DQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELR 225
           D+ EEAEA  AA AE AAAA AA A  E    ++ VE+           E  + EEE+  
Sbjct: 189 DEAEEAEAAAAA-AEAAAAAEAAAAAAE----VIVVEDEEE--------EEKEEEEEKEE 235

Query: 226 EEEVADEEASQEWHAEAPGGGD 247
           EEE  +EE   E   E  GGG+
Sbjct: 236 EEEEGEEEGGGEEGEEGGGGGE 257



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 14/88 (15%)

Query: 161 KEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPE 220
           KE   +++++ EAE   EAE AAAAA A A         A E  +A +E  +V +  + E
Sbjct: 179 KEYIAEKQKDDEAE---EAEAAAAAAEAAA---------AAEAAAAAAEVIVVEDEEEEE 226

Query: 221 EEELREEEVADEEASQEWHAE--APGGG 246
           +EE  E+E  +EE  +E   E    GGG
Sbjct: 227 KEEEEEKEEEEEEGEEEGGGEEGEEGGG 254



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 30/109 (27%), Positives = 38/109 (34%), Gaps = 7/109 (6%)

Query: 131 KPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATA 190
           K  DD+  E E       A    E A    +    + EEE E E   E E          
Sbjct: 185 KQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEG 244

Query: 191 VDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEV-ADEEASQEW 238
             EE       E G    E     E  + EEEE  EE++ A +E  + W
Sbjct: 245 GGEEG------EEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRW 287


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/132 (31%), Positives = 51/132 (38%), Gaps = 11/132 (8%)

Query: 96  ASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPED 155
           A+E G+  G   E  AA G+E      G  G   G P + KP E    P K  A D  + 
Sbjct: 204 AAEAGAASG---EQAAAPGEEAAAGEEGAAG---GDPQEAKPQEAAVAPEKPPASDETKA 257

Query: 156 APKRPKEAAPDQEEEAEAERAAEAERAAAAAA---ATAVDEESPFLVAVENG-SAPS-EP 210
           A +  K      EE   +  A EA  AA   A     A   E P   A  +  +APS E 
Sbjct: 258 AEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEA 317

Query: 211 GLVCEPPQPEEE 222
              C P  P  E
Sbjct: 318 QPECSPEAPPAE 329



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 20/123 (16%)

Query: 88  VQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKR 147
           V     P A+E G+ +       A   D+++P  AG G           P+  EKG  + 
Sbjct: 41  VNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAAS--------PSAAEKG--EP 90

Query: 148 SAGDPPEDAPKRPKEAAPDQEEEAE--AERAAEAERAAAAAAATAVDEESPFLVAVENGS 205
           +A   PE      ++ AP + E AE  +  AAE E A+AA++ +     SP     E+G+
Sbjct: 91  AAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTS-----SP---KAEDGA 142

Query: 206 APS 208
            PS
Sbjct: 143 TPS 145



 Score = 33.1 bits (74), Expect = 0.24
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 32/202 (15%)

Query: 67  GKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGG 126
           G+P       AG   +E     +      A+E GS      E  +A      P    G  
Sbjct: 88  GEPAAAAAPEAGASPVEKEAPAEGE----AAEPGSPTAAEGEAASAASSTSSPKAEDGAT 143

Query: 127 DELGKPDDDKPTEEEKG-PLKRSAGDPPEDAPKRPKEAAPDQEEEAEA-----ERAAEAE 180
                P ++ P +++K    K+S         K  KEA    E EA A     + AA   
Sbjct: 144 PS---PSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGA 200

Query: 181 RAAAAAAATAVDEESPF----LVAVENGSA---------------PSEPGLVCEPPQPEE 221
            AAAA A  A  E++        A E G+A               P +P    E    EE
Sbjct: 201 AAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEE 260

Query: 222 EELREEEVADEEASQEWHAEAP 243
               EE+ A+E  +     EAP
Sbjct: 261 PSKVEEKKAEEAGASAAACEAP 282



 Score = 33.1 bits (74), Expect = 0.24
 Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 33/148 (22%)

Query: 97  SEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDA 156
           ++K +G+G   E  AAEG +D+   A GG                      +A      A
Sbjct: 174 NKKEAGEGGEAEAPAAEGGKDE---AAGGA---------------------AAAAAEAGA 209

Query: 157 PKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEP 216
               + AAP +E  A  E AA  +   A     AV  E P           S+     E 
Sbjct: 210 ASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKP---------PASDETKAAEE 260

Query: 217 PQPEEEELREEEVADEEASQEWHAEAPG 244
           P   EE+  EE  A   A +   A  PG
Sbjct: 261 PSKVEEKKAEEAGASAAACEAPSAAGPG 288



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 12/106 (11%)

Query: 109 PEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLK--RSAGDPPEDAPKRPKEAAPD 166
           P  A G E+      G         D  P   E G  +  ++ G  P    + P  A   
Sbjct: 28  PSKANGQENGHVKVNG---------DASPAAAESGAKEELQANGSAPAADKEEPAAAGSG 78

Query: 167 QEEEAEAERAAEAERAAAAAAATAVDEESPFL-VAVENGSAPSEPG 211
               + AE+   A  AA  A A+ V++E+P    A E GS  +  G
Sbjct: 79  AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEG 124


>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
           sapiens]
          Length = 674

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 64/245 (26%), Positives = 92/245 (37%), Gaps = 50/245 (20%)

Query: 43  FGTHETAFLSPKRLFPYKECKEKFGKPNKRRGFSAGLWEIE-----NNPTVQASDCPLAS 97
           F   + A LSP  L    +  +K   P + +    G+ E E     + P      CP   
Sbjct: 134 FADGQRAPLSPSLLIRTLQGSDK--NPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVE 191

Query: 98  EKGSGDGPWPEPE----AAEGDEDKP-THAGGGGDELGKPDDDKPTEEEKGPLK-----R 147
           E+   +    E      +A     KP T     G+E  +  +DK TE  KG  K     R
Sbjct: 192 EEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPR 251

Query: 148 SAGDPPEDAPKRPKEAAPDQEEEAEAE----RAAEAERAAAAAAATAV--------DEES 195
           S+G  P     R  EA+ ++EE+A  E     AA   +++A A    +        DEE 
Sbjct: 252 SSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEE 311

Query: 196 PFLVAV----ENGSAPSEPGLVCEPP--------------QPEEEELREEEVADEEASQE 237
             + A+    ++G A   P   C PP                EEEE  EE+   +  S E
Sbjct: 312 GEVKALGAAEKDGEAECPP---CIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDE 368

Query: 238 WHAEA 242
              EA
Sbjct: 369 EEGEA 373



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 36/170 (21%), Positives = 62/170 (36%), Gaps = 24/170 (14%)

Query: 81  EIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEE 140
           E E+    + SD     E+G  +     P      +      G   +E    D D  + E
Sbjct: 352 EEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAE 411

Query: 141 EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVA 200
           ++   + SA  PP  A  +     P ++ E E +   ++E           D+E     A
Sbjct: 412 DEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSE-----------DKEDDSEAA 460

Query: 201 VENGSAPSEPGLVCEPPQPEEEE-------LREEEVADEEASQEWHAEAP 243
           +  G A S+P     P  P++            +E  +EEA+++W    P
Sbjct: 461 L--GEAESDP----HPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEP 504


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 53/187 (28%), Positives = 70/187 (37%), Gaps = 20/187 (10%)

Query: 60  KECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEA---AEGDE 116
           KE KE+ GK  +      G  E E     + +  P A E  S     PE EA    + + 
Sbjct: 476 KEAKEEEGKEEE------GGEEEEAEGGEEETKSPPAEEAAS-----PEKEAKSPVKEEA 524

Query: 117 DKPTHAGGGGDELGK-PDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAER 175
             P  A     E  K P + K  E+ K P K  A  PPE A    KE A    E    E+
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE-AKSPEKEEAKSPAEVKSPEK 583

Query: 176 AAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEAS 235
           A    +  A + A A   E       E   +P+E     + P  EE +   E  + E+A 
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE----AKSPVKEEAKSPAEVKSPEKAK 639

Query: 236 QEWHAEA 242
                EA
Sbjct: 640 SPTKEEA 646



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 20/126 (15%)

Query: 133 DDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEE-------AEAERAAEAERAAAA 185
           ++ K  E+ K PLK  A  P ++ PK+ +  +P +EEE        E  + AE E+A A 
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850

Query: 186 AAA----TAVDEESPFLVA----VENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
                   +  EE+P   A    VE    P+      E P+  + E ++EE  D++    
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA-----VEKPKESKVEAKKEEAEDKKKVPT 905

Query: 238 WHAEAP 243
              EAP
Sbjct: 906 PEKEAP 911



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 5/125 (4%)

Query: 127 DELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEA-ERAAAA 185
           +E GK ++    EE +G  + +   P E+A    KEA    +EEA++   A++ E+  A 
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539

Query: 186 AAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAPGG 245
           + A     E     A E   +P E     + P+ EE +   E  + E+A      EA   
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPE----AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595

Query: 246 GDRDS 250
            +  S
Sbjct: 596 AEAKS 600



 Score = 36.2 bits (82), Expect = 0.028
 Identities = 48/205 (23%), Positives = 77/205 (37%), Gaps = 28/205 (13%)

Query: 52  SPKRLFPYKE---CKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPE 108
           SP   FP K     KE+   P K +        ++ +      + P   E  S     P 
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKS------PLKEDAKAPEKEIPKKEEVKS-----PV 824

Query: 109 PEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQE 168
            E  +  E K        +E   P   K TEE+K   K  A       PK  ++  P  E
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883

Query: 169 EEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVC----------EPPQ 218
           +  E++  A+ E A         ++E+P  V V+  + P E   V           EP +
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943

Query: 219 PEEEELREEEVADEEASQEWHAEAP 243
           P E   ++E   +++ ++E  A+ P
Sbjct: 944 PAE---KKEAAPEKKDTKEEKAKKP 965



 Score = 35.0 bits (79), Expect = 0.062
 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 127 DELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAA 186
           +E  K   ++  +EE+G  +  A    E+    P E A   E+EA++    EA+  A A 
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531

Query: 187 AATAVDEESPFLV-AVENGSAPSEPGLVCEP--PQPEEEELRE----------EEVADEE 233
           +    + +SP  V + E   +P++      P    PE+EE +           +  A EE
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591

Query: 234 ASQEWHAEAP 243
           A     A++P
Sbjct: 592 AKSPAEAKSP 601



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 15/144 (10%)

Query: 110 EAAEGDEDKPTHAGGGGDELGKPDDDKPTEEE-KGPLKRSAGDPPEDAPKRP-KEAA--- 164
           E  E +E +     G  +E G+ ++ +  EEE K P    A  P ++A K P KE A   
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA-KSPVKEEAKSP 527

Query: 165 -----PDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQP 219
                P++EE          E+A + A   A           E   +P+E     + P+ 
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE----VKSPEK 583

Query: 220 EEEELREEEVADEEASQEWHAEAP 243
            +   +EE  +  EA     A++P
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSP 607



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 12/151 (7%)

Query: 52   SPKRLFPYKECKEK----FGKPNKRRGFSAGLWEIENNPTVQA--SDCPLASEKGSGDGP 105
            +PK+  P  + +EK      KP + +   A   E E+   V     + P   E      P
Sbjct: 864  APKKEAPKPKVEEKKEPAVEKPKESK-VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP 922

Query: 106  WPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAP 165
              + E A+ + D          E  KP + K    EK   K      PE+ PK   +A  
Sbjct: 923  KEKTEVAKKEPDDAK-----AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977

Query: 166  DQEEEAEAERAAEAERAAAAAAATAVDEESP 196
            D +  ++     +AE+A  +++    D + P
Sbjct: 978  DDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008



 Score = 32.7 bits (73), Expect = 0.31
 Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 6/117 (5%)

Query: 127 DELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAA 186
           +E   P+  K   +E+      A  P ++  K P++A    +EEA++   A++   A   
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759

Query: 187 AATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAP 243
              + + ++P   A E   +P++     +   P +EE++  E A     ++  A+AP
Sbjct: 760 DVKSPEAKTP---AKEEARSPADK-FPEKAKSPVKEEVKSPEKAKSPLKED--AKAP 810



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)

Query: 107 PEPEAAEGDED--KPTHAGGGGDELGKPD---DDKPTEEEKGPLKRSAGDPP-------E 154
           PE E A+  E    P  A     E  K     + K  E+ K P+K  A  P        E
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714

Query: 155 DAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVC 214
           +A    K  +P +EE    E+A    +  A +   A   E    + V++  A +      
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774

Query: 215 EPPQPEEEELREEEVADEEASQE 237
             P  +  E  +  V +E  S E
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPE 797



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 3/116 (2%)

Query: 128 ELGKPDDDK-PTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAA 186
           E+  P+  K PT+EE    +++     E+A    K  +P + E    E+A    +A A +
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690

Query: 187 AATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEA 242
              A         + E   +P +     + P+  +  ++EE    E+A      EA
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKE--EAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 29/108 (26%), Positives = 43/108 (39%), Gaps = 17/108 (15%)

Query: 135 DKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEE 194
           ++ TEEE+   K   G          KE    +EEEAE          A  AA+   + +
Sbjct: 468 EEVTEEEEKEAKEEEG----------KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517

Query: 195 SPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEA 242
           SP     E   +P+E     + P+ EE +   E  + E+A      EA
Sbjct: 518 SP---VKEEAKSPAE----AKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 25/112 (22%), Positives = 50/112 (44%), Gaps = 9/112 (8%)

Query: 127 DELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEA----ERA 182
           +E   P+  K  E+E+      A  P +   K P++A    + EA++   A++    E  
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703

Query: 183 AAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEA 234
           +   A + V EE+    + E   +P +     + P+  +  ++EE  + E+A
Sbjct: 704 SPEKAKSPVKEEAK---SPEKAKSPVKE--EAKTPEKAKSPVKEEAKSPEKA 750


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 48/187 (25%), Positives = 75/187 (40%), Gaps = 22/187 (11%)

Query: 68   KPNKRR--GFSAGLWEIENNPTVQASDCPLASEKGSGDGPW-PEPEAAEGDEDKPTHAGG 124
            + NK R  GF   L+     P        +  +K + +G   P P   E +E K T    
Sbjct: 1260 RQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIE-EEVKET---- 1314

Query: 125  GGDELGKPDDDKPTEEEKGPLK--RSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERA 182
             G+ L  P ++   EE   P+    S G+ PED   +P+E   ++EEE E E   E E  
Sbjct: 1315 -GEAL-LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372

Query: 183  AAAA-------AATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEAS 235
                        A + ++E P +   +  SA  +     E  + E+EE    E  D +  
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDH---EEEEEEDEEPSHNEDHDADDE 1429

Query: 236  QEWHAEA 242
             + H E+
Sbjct: 1430 DDSHMES 1436



 Score = 34.7 bits (78), Expect = 0.081
 Identities = 33/118 (27%), Positives = 45/118 (38%), Gaps = 9/118 (7%)

Query: 136  KPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEA------ERAAAAAAAT 189
            +  +E K   K +   PPE  P  P E    +E++  +E           E       A 
Sbjct: 1260 RQNKERKTGFKLNLYTPPE-TPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEAL 1318

Query: 190  AVDEESPFLVAVENGSAPSEPGLVCEPP--QPEEEELREEEVADEEASQEWHAEAPGG 245
               EE+         S  + PG   E    +PEEEE  EEE  +EE  +E   E  GG
Sbjct: 1319 LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG 1376



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 17/91 (18%)

Query: 168  EEEAEAERAAE-----------------AERAAAAAAATAVDEESPFLVAVENGSAPSEP 210
            EEE EAE+ AE                 + RA +  +   V  ++ +L + E+     E 
Sbjct: 999  EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058

Query: 211  GLVCEPPQPEEEELREEEVADEEASQEWHAE 241
            G + E  +   EE  EEE  +EE  +E   E
Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEE 1089



 Score = 31.6 bits (70), Expect = 0.68
 Identities = 35/152 (23%), Positives = 59/152 (38%), Gaps = 14/152 (9%)

Query: 108  EPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGD-----------PPEDA 156
            E E  E +E++     GGG+    PD  K  E+E+  +     D             ++ 
Sbjct: 1358 EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417

Query: 157  PKRPKEAAPDQEEEAEAERA-AEAERAAAAAAATAVDEESPFL-VAVENGSAPSEPGLVC 214
            P   ++   D E+++  E A  E E     +    ++ +  FL + V+ G +  E  + C
Sbjct: 1418 PSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDC 1477

Query: 215  EPPQPEEEELREEEVA-DEEASQEWHAEAPGG 245
                        +E+A D EA  E   E P G
Sbjct: 1478 GVDLTASCNSEPKELAGDPEAVPESDEEPPPG 1509



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 27/120 (22%)

Query: 131  KPDDDKPTEEEKGPLKRSAGDPP---EDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAA 187
            +PD+    EE+K   +      P   E+  K   EA   QEE    E  A          
Sbjct: 1282 EPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCA---------- 1331

Query: 188  ATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHAEAPGGGD 247
                    P       G  P +   + +P + EEEE  EEE  +EE  +E   E  GGG+
Sbjct: 1332 --------PVSPNTSPGEKPEDD--LIKPEEEEEEE--EEE--EEEEEEEEGEEEEGGGN 1377



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 18/77 (23%), Positives = 32/77 (41%), Gaps = 5/77 (6%)

Query: 128  ELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAA 187
            EL K   ++  EEE    +    +  ED     +E   ++EEE E E    +        
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEED-----EEEEEEEEEEEEEENIQSSPPRLTKPQ 1117

Query: 188  ATAVDEESPFLVAVENG 204
            + A+  + PF++  + G
Sbjct: 1118 SVAIKRKRPFVLKKKRG 1134


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 38/150 (25%), Positives = 62/150 (41%), Gaps = 7/150 (4%)

Query: 99  KGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPP----E 154
           KG+ +G   + E ++ +ED  +      DE    D+D   E E   +K +A  P     +
Sbjct: 132 KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDED---EIEPAAMKAAAAAPASEDED 188

Query: 155 DAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVC 214
           D      E   D EE+   E A E   A    AA  V  ++  +   E+     E     
Sbjct: 189 DEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD 248

Query: 215 EPPQPEEEELREEEVADEEASQEWHAEAPG 244
           +    E+++  ++E  +EE  +E   EAPG
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEEPVKEAPG 278



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 12/82 (14%)

Query: 94  PLASEKGSGDGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPP 153
           P+ ++  + D    E +  E D+D         DE  + DDD+  EEE+   +    +P 
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDD---------DEDDEDDDDEDDEEEE---EEEEEEPV 273

Query: 154 EDAPKRPKEAAPDQEEEAEAER 175
           ++AP + K+    Q+   EA++
Sbjct: 274 KEAPGKRKKEMAKQKAAPEAKK 295



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 27/108 (25%), Positives = 39/108 (36%), Gaps = 18/108 (16%)

Query: 130 GKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAAT 189
           GK     P +  K        D  E+     +E   D E+E E E   E     AAAAA 
Sbjct: 123 GKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182

Query: 190 AVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
           A ++E                    E  + +E++  +EE   EE + E
Sbjct: 183 ASEDEDD------------------EDDEDDEDDDDDEEDDSEEEAME 212


>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 18/181 (9%)

Query: 12  GDLVFAKLKGYAHWPARIEHMTQPNRYQ-------VFFFGTHETAFLSPKRLFPYKECKE 64
           G+LV+ KL+G++ WP RI       R +       V +FG  + + +  ++L P      
Sbjct: 293 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCS 352

Query: 65  KFGKP--NKRRGFSAGLWEIENNPTVQASDC-PLASEKGSGDGPWPEPEAAEGDEDKPTH 121
            F +   NK+  +   ++E+    + +A    P+  +    D      +A E        
Sbjct: 353 AFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESD----TAKAVEVQNKPMIE 408

Query: 122 AGGGGDELGKPDDDKPTEEEKGPLKRSAGD----PPEDAPKRPKEAAPDQEEEAEAERAA 177
              GG +   P   +P EEEK P K    D    P   A   P  A   ++  AE  +  
Sbjct: 409 WALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVK 468

Query: 178 E 178
           E
Sbjct: 469 E 469


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 18/181 (9%)

Query: 12  GDLVFAKLKGYAHWPARIEHMTQPNRYQ-------VFFFGTHETAFLSPKRLFPYKECKE 64
           G+LV+ KL+G++ WP RI       R +       V +FG  + + +  ++L P      
Sbjct: 293 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCS 352

Query: 65  KFGKP--NKRRGFSAGLWEIENNPTVQASDC-PLASEKGSGDGPWPEPEAAEGDEDKPTH 121
            F +   NK+  +   ++E+    + +A    P+  +    D      +A E        
Sbjct: 353 AFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESD----TAKAVEVQNKPMIE 408

Query: 122 AGGGGDELGKPDDDKPTEEEKGPLKRSAGD----PPEDAPKRPKEAAPDQEEEAEAERAA 177
              GG +   P   +P EEEK P K    D    P   A   P  A   ++  AE  +  
Sbjct: 409 WALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVK 468

Query: 178 E 178
           E
Sbjct: 469 E 469


>gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Homo
           sapiens]
          Length = 723

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 18/181 (9%)

Query: 12  GDLVFAKLKGYAHWPARIEHMTQPNRYQ-------VFFFGTHETAFLSPKRLFPYKECKE 64
           G+LV+ KL+G++ WP RI       R +       V +FG  + + +  ++L P      
Sbjct: 104 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCS 163

Query: 65  KFGKP--NKRRGFSAGLWEIENNPTVQASDC-PLASEKGSGDGPWPEPEAAEGDEDKPTH 121
            F +   NK+  +   ++E+    + +A    P+  +    D      +A E        
Sbjct: 164 AFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESD----TAKAVEVQNKPMIE 219

Query: 122 AGGGGDELGKPDDDKPTEEEKGPLKRSAGD----PPEDAPKRPKEAAPDQEEEAEAERAA 177
              GG +   P   +P EEEK P K    D    P   A   P  A   ++  AE  +  
Sbjct: 220 WALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVK 279

Query: 178 E 178
           E
Sbjct: 280 E 280


>gi|217035154 RCSD domain containing 1 [Homo sapiens]
          Length = 416

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 22/161 (13%)

Query: 89  QASDCPLASEKGSGDG-----PWPEP-------EAAEGDEDKPTHAGGGGDELGKP---- 132
           +A   PL+SE  +G+G     P  +P          + +ED+ T     G++  +     
Sbjct: 212 KAPGSPLSSEGAAGEGVRTLGPAEKPPLRRSPSRTEKQEEDRATEEAKNGEKARRSSEEV 271

Query: 133 DDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAAAAAAATAVD 192
           D   P +EE     +++G   E+    P+E  P   EEAE E+A E +           +
Sbjct: 272 DGQHPAQEEVPESPQTSGPEAENRCGSPREEKP-AGEEAEMEKATEVKGERVQNEEVGPE 330

Query: 193 EESPFLVAVENGSAPSE-----PGLVCEPPQPEEEELREEE 228
            +S     +E G+A  E     PG V     P++E+ +E++
Sbjct: 331 HDSQETKKLEEGAAVKETPHSPPGGVKGGDVPKQEKGKEKQ 371


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 50/182 (27%), Positives = 68/182 (37%), Gaps = 26/182 (14%)

Query: 81  EIENNPTVQASDCPLASEKGSGD-GPWPEPEAAEGDEDKPTHAGGGGDELGKP------- 132
           E +  P VQ    P   + G GD G  P P+A   ++      GGG    G P       
Sbjct: 582 EADGQPAVQ----PAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAG 637

Query: 133 DDDKPTEEE----KGPLKR-----SAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAERAA 183
           D  +P E+     K PL         G PPE   +R  E A   +  ++ E A  AE   
Sbjct: 638 DTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLD 697

Query: 184 AAAAATAVDEESPFLVAVENGSAPSEPGL-VCEPPQPEEEELREEEVADEEASQEWHAEA 242
            A     + E+    V  +      E  L V E    E  + R+E+  D+    E H E 
Sbjct: 698 HAVLLQVIKEQQ---VQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQE- 753

Query: 243 PG 244
           PG
Sbjct: 754 PG 755



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 30/150 (20%)

Query: 107 PEPEAAEGDEDKPT-------HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKR 159
           PE +A E  E+ P         A GG     +  + +  E  +GP+ R    PP      
Sbjct: 765 PEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPP------ 818

Query: 160 PKEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQP 219
             +  PD E  A   +  + ++ AA  AA  V E             P  P  V  P   
Sbjct: 819 --DGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKE------------LPKGPEQVPVPDPA 864

Query: 220 EEEELREEEVADEEASQEWHAEAPGGGDRD 249
            E    EE +A+E   Q   ++   GG +D
Sbjct: 865 REAGGPEERLAEEFPGQ---SQDVTGGSQD 891


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.129    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,293,395
Number of Sequences: 37866
Number of extensions: 822195
Number of successful extensions: 8228
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 687
Number of HSP's that attempted gapping in prelim test: 4768
Number of HSP's gapped (non-prelim): 2821
length of query: 251
length of database: 18,247,518
effective HSP length: 100
effective length of query: 151
effective length of database: 14,460,918
effective search space: 2183598618
effective search space used: 2183598618
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.