Guide to the Human Genome
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Name: DNMT3A Sequence: fasta or formatted (912aa) NCBI GI: 28559069
Description:

DNA cytosine methyltransferase 3 alpha isoform a

Referenced in:

DNA Methylation

Other entries for this name:
alt mRNA [912aa] DNA cytosine methyltransferase 3 alpha isoform a
alt prot [166aa] DNA cytosine methyltransferase 3 alpha isoform c
alt prot [723aa] DNA cytosine methyltransferase 3 alpha isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         67           3
 C cysteine            3.1         28           2
 D aspartate           5.2         47           3
 E glutamate           9.3         85           3
 F phenylalanine       3.5         32           2
 G glycine             8.8         80           2
 H histidine           1.5         14           1
 I isoleucine          3.4         31           2
 K lysine              6.6         60           2
 L leucine             5.8         53           2
 M methionine          2.7         25           1
 N asparagine          3.2         29           3
 P proline             7.7         70           4
 Q glutamine           3.5         32           2
 R arginine            7.1         65           3
 S serine              6.5         59           3
 T threonine           3.6         33           2
 V valine              6.5         59           2
 W tryptophan          2.1         19           2
 Y tyrosine            2.6         24           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA cytosine methyltransferase 3 alpha isoform a [Ho... 
DNMT3A                1.000   DNA cytosine methyltransferase 3 alpha isoform a [Ho...
DNMT3A                0.769   DNA cytosine methyltransferase 3 alpha isoform b [Ho...
DNMT3B                0.428   DNA cytosine-5 methyltransferase 3 beta isoform 6 [H...
DNMT3B                0.428   DNA cytosine-5 methyltransferase 3 beta isoform 2 [H...
DNMT3B                0.426   DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho...
DNMT3B                0.332   DNA cytosine-5 methyltransferase 3 beta isoform 3 [H...
DNMT3A                0.151   DNA cytosine methyltransferase 3 alpha isoform c [Ho...
DNMT3L                0.121   cytosine-5-methyltransferase 3-like protein isoform ...
DNMT3L                0.121   cytosine-5-methyltransferase 3-like protein isoform ...
PWWP2B                0.022   PWWP domain containing 2 isoform 1 
PWWP2A                0.019   PWWP domain containing 2A isoform b 
C4orf8                0.016   hypothetical protein LOC8603 
NES                   0.015   nestin 
SMTNL1                0.014   smoothelin-like 1 
NEFH                  0.013   neurofilament, heavy polypeptide 200kDa 
RP1L1                 0.012   retinitis pigmentosa 1-like 1 
RPGR                  0.012   retinitis pigmentosa GTPase regulator isoform C [Hom...
OGFR                  0.011   opioid growth factor receptor 
ATRX                  0.011   transcriptional regulator ATRX isoform 1 
ATRX                  0.011   transcriptional regulator ATRX isoform 2 
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform e...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform d...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform a ...
TCOF1                 0.011   Treacher Collins-Franceschetti syndrome 1 isoform c ...
GTF2F1                0.011   general transcription factor IIF, polypeptide 1, 74...
HNRNPUL2              0.010   heterogeneous nuclear ribonucleoprotein U-like 2 [H...
HCN4                  0.010   hyperpolarization activated cyclic nucleotide-gated p...
LOC100292262          0.010   PREDICTED: hypothetical protein 
ZNF335                0.010   zinc finger protein 335 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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