Guide to the Human Genome
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Search of human proteins with 188536055

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
         (403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]             827   0.0  
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]             704   0.0  
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]             704   0.0  
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]               410   e-114
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa...   360   1e-99
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]          338   7e-93
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]             206   4e-53
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]   205   5e-53
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s...   201   1e-51
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ...   194   1e-49
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]      159   4e-39
gi|27436871 carboxypeptidase O [Homo sapiens]                         143   2e-34
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]              96   8e-20
gi|22202611 carboxypeptidase D precursor [Homo sapiens]                47   3e-05
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]             44   2e-04
gi|53832021 carboxypeptidase M precursor [Homo sapiens]                44   2e-04
gi|38327526 carboxypeptidase M precursor [Homo sapiens]                44   2e-04
gi|6631081 carboxypeptidase M precursor [Homo sapiens]                 44   2e-04
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]                42   0.001
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]      42   0.001
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]                42   0.001
gi|4503493 early growth response 1 [Homo sapiens]                      35   0.16 
gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens]             33   0.35 
gi|239754026 PREDICTED: hypothetical protein [Homo sapiens]            32   1.3  
gi|239748557 PREDICTED: hypothetical protein XP_002346722 [Homo ...    32   1.3  
gi|239742540 PREDICTED: hypothetical protein XP_002342571 [Homo ...    32   1.3  
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]    31   1.7  
gi|122937233 discs, large (Drosophila) homolog-associated protei...    30   3.9  
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             30   3.9  
gi|38373671 SEC24-related protein C [Homo sapiens]                     30   3.9  

>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
          Length = 403

 Score =  827 bits (2136), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60
           MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE
Sbjct: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60

Query: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120
           GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA
Sbjct: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120

Query: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180
           MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS
Sbjct: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180

Query: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240
           TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP
Sbjct: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240

Query: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300
           DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE
Sbjct: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300

Query: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELMWPVGSPSTGPMTV 360
           PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELMWPVGSPSTGPMTV
Sbjct: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELMWPVGSPSTGPMTV 360

Query: 361 ASSTPSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGPSWSTP 403
           ASSTPSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGPSWSTP
Sbjct: 361 ASSTPSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGPSWSTP 403


>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
          Length = 436

 Score =  704 bits (1817), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60
           MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE
Sbjct: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60

Query: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120
           GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA
Sbjct: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120

Query: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180
           MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS
Sbjct: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180

Query: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240
           TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP
Sbjct: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240

Query: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300
           DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE
Sbjct: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300

Query: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL 346
           PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL
Sbjct: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL 346


>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
          Length = 436

 Score =  704 bits (1817), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60
           MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE
Sbjct: 1   MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE 60

Query: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120
           GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA
Sbjct: 61  GLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQA 120

Query: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180
           MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS
Sbjct: 121 MAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFS 180

Query: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240
           TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP
Sbjct: 181 TGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNP 240

Query: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300
           DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE
Sbjct: 241 DGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSE 300

Query: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL 346
           PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL
Sbjct: 301 PEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQREL 346


>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
          Length = 419

 Score =  410 bits (1053), Expect = e-114
 Identities = 193/328 (58%), Positives = 247/328 (75%)

Query: 19  RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
           R LLV S +L A  G+ +F G QVLR+   DE Q+  + +LE L+  ++DFWRGPA P  
Sbjct: 2   RGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGS 61

Query: 79  PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
           P+D+RVPF  ++ +K +LESHG++Y  MI+D+Q LLDEE++ M   R   RST++F+Y++
Sbjct: 62  PIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121

Query: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
           YHTLEEIY ++D  V E+  +VSKIQIGN++E + I VLKFSTGGS+ PAIWIDTGIHSR
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSR 181

Query: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
           EW+T A+G+W A KI  DYG+D   T IL+ +DIF+E+VTNPDGFAFTHS NR+WRK +S
Sbjct: 182 EWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRS 241

Query: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
              G  CIGVD NRNW +GFG +G++SNPCSETYHG    SE EV +IV+F+  HGN KA
Sbjct: 242 HTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKA 301

Query: 319 LISIHSYSQMLMYPYGRLLEPVSNQREL 346
            ISIHSYSQ+LMYPYG   EPV +Q EL
Sbjct: 302 FISIHSYSQLLMYPYGYKTEPVPDQDEL 329


>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
           sapiens]
          Length = 419

 Score =  360 bits (924), Expect = 1e-99
 Identities = 172/316 (54%), Positives = 230/316 (72%), Gaps = 2/316 (0%)

Query: 19  RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
           R +L F  +         F GDQVL ++  +E+Q+  L  LE  +  ++DFW+ P  P  
Sbjct: 4   RLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGE 63

Query: 79  PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
              +RVPF  ++ +K +LES G+AYSIMI+D+QVLLD+E + M  +RR ERS N F++ +
Sbjct: 64  TAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGA 122

Query: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
           YHTLEEI   +DN V EH  +VSK+ IG+SFEN+ + VLKFSTGG + PAIW+D GIH+R
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAR 181

Query: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
           EW+T AT +WTANKIVSDYGKD  +T IL+A+DIF+  VTNPDG+ F+ + NR+WRK +S
Sbjct: 182 EWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRS 241

Query: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
              G  C+GVD NRNW +GFGG G++SNPCS++YHGPS  SE EV +IV+FI +HG  KA
Sbjct: 242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKA 301

Query: 319 LISIHSYSQMLMYPYG 334
            I++HSYSQ+LM+PYG
Sbjct: 302 FITLHSYSQLLMFPYG 317


>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
          Length = 421

 Score =  338 bits (866), Expect = 7e-93
 Identities = 161/330 (48%), Positives = 220/330 (66%), Gaps = 1/330 (0%)

Query: 18  RRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPS 77
           R  L + + I ++  GQ  F GDQVLR+  ++  ++S L  L      K++FW+ P+  +
Sbjct: 2   RWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFN 61

Query: 78  LPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYS 137
            PVD+ VP   L+  K++L S GL Y++ I+D+Q LLD E   M  +   ERS+N+F+Y 
Sbjct: 62  RPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYG 121

Query: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTG-GSRHPAIWIDTGIH 196
           +YH+LE IY  +DN   +  D+  +++IG+SFEN+ + VLKFSTG G R PA+W++ GIH
Sbjct: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIH 181

Query: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256
           SREWI+ AT IWTA KIVSDY +D  +T IL  MDIF+  V NPDG+ +T + NRLWRK 
Sbjct: 182 SREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKT 241

Query: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNF 316
           +S  PG  CIG D NRNW + F G G++ NPCSE YHGP   SE EV ++V+FI  HGNF
Sbjct: 242 RSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNF 301

Query: 317 KALISIHSYSQMLMYPYGRLLEPVSNQREL 346
           K  I +HSYSQ+LMYPYG  ++   +  EL
Sbjct: 302 KGFIDLHSYSQLLMYPYGYSVKKAPDAEEL 331


>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
          Length = 417

 Score =  206 bits (523), Expect = 4e-53
 Identities = 109/321 (33%), Positives = 185/321 (57%), Gaps = 13/321 (4%)

Query: 31  ALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPAR----PSLPVDMRVPF 86
           A+  + F  ++V RV  +DEKQ  ++ DL   K  ++DFW   A      ++ VD RV  
Sbjct: 15  AIAPVRFDREKVFRVKPQDEKQADIIKDLA--KTNELDFWYPGATHHVAANMMVDFRVSE 72

Query: 87  SELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIY 146
            E + I++ L+ + + Y I+I D+Q  ++++          E      SY+ Y+  E+I 
Sbjct: 73  KESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVK------EDIPGRHSYAKYNNWEKIV 126

Query: 147 SWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATG 206
           +W +  + ++ ++VS+I+IG++ E+  + VLK      R  AI+ D GIH+REW++ A  
Sbjct: 127 AWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFC 186

Query: 207 IWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCI 266
            W   +    YG+++++T +L+ M+ +I  V N DG+ ++ + NR+WRKN+S      CI
Sbjct: 187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCI 246

Query: 267 GVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSY 325
           G DLNRN+ + +    + ++PC++ Y G +P+SE E  A+ NFI +H N  K  I+ HSY
Sbjct: 247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSY 306

Query: 326 SQMLMYPYGRLLEPVSNQREL 346
           SQML++PYG   +   N  +L
Sbjct: 307 SQMLLFPYGYTSKLPPNHEDL 327


>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
          Length = 437

 Score =  205 bits (522), Expect = 5e-53
 Identities = 107/313 (34%), Positives = 173/313 (55%), Gaps = 9/313 (2%)

Query: 37  FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RPSLPVDMRVPFSELKDI 92
           + GD+V+R + K E++   L  +      KVD W+  +          D+ +P +  + +
Sbjct: 37  YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94

Query: 93  KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
            A+L+   + Y ++I+D+Q  L  E+ +   ++R  RS + ++Y  YH+LEEI +W+ + 
Sbjct: 95  LAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHL 152

Query: 153 VMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANK 212
              HS ++    IG S+E +S+ +LK         A+WID GIH+REWI  A   W   +
Sbjct: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212

Query: 213 IVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNR 272
            +  Y  D  +  +LN +  +I  V N DG+ F+ + +R WRK +S      C GVD NR
Sbjct: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272

Query: 273 NWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMY 331
           NWK  +   G++ +PC +TY GP P+SEPEV A+ NF+  H  + +A +S H+Y+QML+Y
Sbjct: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332

Query: 332 PYGRLLEPVSNQR 344
           PY      + N R
Sbjct: 333 PYSYKYATIPNFR 345


>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
           sapiens]
          Length = 417

 Score =  201 bits (510), Expect = 1e-51
 Identities = 107/331 (32%), Positives = 185/331 (55%), Gaps = 14/331 (4%)

Query: 21  LLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RP 76
           +LV   + +A  G  +F G++V RV  +DE  ++++ +L      ++DFW+  +    +P
Sbjct: 6   VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63

Query: 77  SLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSY 136
              VD RV   +   ++  L+ + L Y ++I +++ +++ +  +  ++          SY
Sbjct: 64  HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRA-------TGHSY 116

Query: 137 SSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIH 196
             Y+  E I +W      E+  ++S+  IG +FE ++I +LK    G   PAI++D G H
Sbjct: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176

Query: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256
           +REWI+ A   W   + V  YG++  +T++L+ +D ++  V N DG+ +T + +R WRK 
Sbjct: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236

Query: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI-TAHGN 315
           +S   G  CIG D NRN+ +G+   G++ NPC ETY GP+ +SE E  A+ +FI     +
Sbjct: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296

Query: 316 FKALISIHSYSQMLMYPYGRLLEPVSNQREL 346
            KA ++IHSYSQM++YPY    +   N  EL
Sbjct: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAEL 327


>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
           [Homo sapiens]
          Length = 423

 Score =  194 bits (493), Expect = 1e-49
 Identities = 115/317 (36%), Positives = 175/317 (55%), Gaps = 13/317 (4%)

Query: 37  FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
           F   QVL  L +  +Q+ +L +L      ++  W+      +    +V F    S++ ++
Sbjct: 23  FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80

Query: 93  KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
           KA+L   G+  S+++ D++ L+ ++      S R   S     Y  YH+L EIYSWI+  
Sbjct: 81  KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136

Query: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
              H D+++KI IG+SFE   + VLK S    +   AIWID GIH+REWI+ A  +W   
Sbjct: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196

Query: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
            I   YG     T++L  +D ++  V N DG+ ++   NR+WRKN+S      CIG DLN
Sbjct: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256

Query: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
           RN+ S  +   G++S+ CSETY G  P+SEPEV A+ +F+  + N  KA IS+HSYSQ +
Sbjct: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316

Query: 330 MYPYGRLLEPVSNQREL 346
           ++PY        +  EL
Sbjct: 317 VFPYSYTRSKSKDHEEL 333


>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
          Length = 360

 Score =  159 bits (402), Expect = 4e-39
 Identities = 107/317 (33%), Positives = 159/317 (50%), Gaps = 50/317 (15%)

Query: 37  FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
           F   QVL  L +  +Q+ +L +L      ++  W+      +    +V F    S++ ++
Sbjct: 23  FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80

Query: 93  KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
           KA+L   G+  S+++ D++ L+ ++      S R   S     Y  YH+L EIYSWI+  
Sbjct: 81  KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136

Query: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
              H D+++KI IG+SFE   + VLK S    +   AIWID GIH+REWI+ A  +W   
Sbjct: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLW--- 193

Query: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
                                FI               NR+WRKN+S      CIG DLN
Sbjct: 194 ---------------------FI-------------GHNRMWRKNRSFYANNHCIGTDLN 219

Query: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
           RN+ S  +   G++S+ CSETY G  P+SEPEV A+ +F+  + N  KA IS+HSYSQ +
Sbjct: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279

Query: 330 MYPYGRLLEPVSNQREL 346
           ++PY        +  EL
Sbjct: 280 VFPYSYTRSKSKDHEEL 296


>gi|27436871 carboxypeptidase O [Homo sapiens]
          Length = 374

 Score =  143 bits (361), Expect = 2e-34
 Identities = 74/236 (31%), Positives = 129/236 (54%), Gaps = 2/236 (0%)

Query: 114 LDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQS 173
           L + RQ +        S  ++SY+ YH + EIY W+     ++ ++V++  +G ++E   
Sbjct: 25  LAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHP 84

Query: 174 ILVLKFST-GGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDI 232
           +  LK S   G+    IW+D GIH+REWI  A   W   +I+ ++  +  +  +L  +D 
Sbjct: 85  MYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDF 144

Query: 233 FIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY 292
           ++  V N DG+ +T + +RLWRK++S      C G DLNRN+ + +   G++ N   +T+
Sbjct: 145 YVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTF 204

Query: 293 HGPSPQSEPEVAAIVNFI-TAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELM 347
            G  P SEPE  A+ +FI +   +    +++HSY Q+++ PYG      SN  E++
Sbjct: 205 CGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMI 260


>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
          Length = 193

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 46/120 (38%), Positives = 65/120 (54%)

Query: 156 HSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANKIVS 215
           HS ++    IG S+E +S+ +LK         A+WID GIH+REWI  A   W   + + 
Sbjct: 8   HSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 67

Query: 216 DYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWK 275
            Y  D  +  +LN +  +I  V N DG+ F+ + +R WRK +S      C GVD NRNWK
Sbjct: 68  TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 127


>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
          Length = 1380

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 52/246 (21%), Positives = 101/246 (41%), Gaps = 33/246 (13%)

Query: 108  KDIQVLL-DEERQAMAKSRRLERSTN-SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQI 165
            K+ + L+ D   +   +S  L  S+N + +   YH+ +++  ++   VM +  I +   +
Sbjct: 900  KEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNL 959

Query: 166  GNSFENQSILVLKFSTGGS----RHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDR 221
            G S E + I  L+ S   +      P I    GIH    +     +  A  +  +Y K+ 
Sbjct: 960  GQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKKNP 1019

Query: 222  VLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPG-IFCIGVDLNRNWKSGFGG 280
             +T +++   I I    NPDG        R   K+ + + G     G DL+ ++ +    
Sbjct: 1020 AVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDFTNN--- 1070

Query: 281  NGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPV 340
                              S+PE  AI+  +    +F   +++   S ++ YPY + ++ V
Sbjct: 1071 -----------------ASQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTV 1113

Query: 341  SNQREL 346
             N+  L
Sbjct: 1114 ENKETL 1119



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 40/202 (19%), Positives = 87/202 (43%), Gaps = 30/202 (14%)

Query: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDTG 194
           +H   ++  ++  F  E+ +I     +G S E++ + V++ S     H    P       
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562

Query: 195 IHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTH---SMNR 251
           +H  E +     +     +  ++G D  +TD+++   I +    NPDG+  +    S++ 
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622

Query: 252 LWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFIT 311
           + R N +          DLNRN+   F      ++P           ++PE  A+++++ 
Sbjct: 623 IGRNNSN--------NFDLNRNFPDQF---VQITDP-----------TQPETIAVMSWMK 660

Query: 312 AHGNFKALISIHSYSQMLMYPY 333
           ++  F    ++H  S ++ YP+
Sbjct: 661 SY-PFVLSANLHGGSLVVNYPF 681



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 31/158 (19%)

Query: 187 PAIWIDTGIHSREWITHATGIWTANKIVSDYGK-DRVLTDILNAMDIFIELVTNPDGFAF 245
           P + +   +H  E ++    I+ A ++ + Y + D  L  +LN  D+++    NPDGF  
Sbjct: 130 PQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFER 189

Query: 246 THS----------MNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGP 295
                             R N          G DLNR++   F            T   P
Sbjct: 190 AREGDCGFGDGGPSGASGRDNSR--------GRDLNRSFPDQF-----------STGEPP 230

Query: 296 SPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
           +    PEV A++ +I     F    ++H  S +  YP+
Sbjct: 231 ALDEVPEVRALIEWI-RRNKFVLSGNLHGGSVVASYPF 267


>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
          Length = 476

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 56/234 (23%), Positives = 96/234 (41%), Gaps = 33/234 (14%)

Query: 121 MAKSRRLERSTN-SFSYSSYHTLEE--IYSWIDNFVMEHSDIVSKIQ-IGNSFENQSILV 176
           M + RRL++    SF Y  Y  L E  +  W+          +S+I  +G SFE + +LV
Sbjct: 37  MRRRRRLQQEDGISFEYHRYPELREALVSVWLQ------CTAISRIYTVGRSFEGRELLV 90

Query: 177 LKFSTGGSRH----PAIWIDTGIHSREWITHATGIWTANKIVSDYGK-DRVLTDILNAMD 231
           ++ S     H    P       +H  E +     I+ A  + ++Y K +  + +++++  
Sbjct: 91  IELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTR 150

Query: 232 IFIELVTNPDGFAFTHSMN---RLWRKNKSIRPGIFCIGVDLNRNW---------KSGFG 279
           I I    NPDGF    S     + W   +S   GI     DLNRN+             G
Sbjct: 151 IHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGI-----DLNRNFPDLDRIVYVNEKEG 205

Query: 280 GNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
           G  ++     +     + +  PE  A++++I     F    ++H    +  YPY
Sbjct: 206 GPNNHLLKNMKKIVDQNTKLAPETKAVIHWI-MDIPFVLSANLHGGDLVANYPY 258


>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)

Query: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
           +YH  E + +++      +S +     IG S + +++ VL        H    P      
Sbjct: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80

Query: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
            +H  E +     +   + +V+  GKD  +T+++N+  I I    NPDGF      +   
Sbjct: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140

Query: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
            + R+N +          DLNRN+   F  N              +   +PE  A++ ++
Sbjct: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178

Query: 311 TAHGNFKALISIHSYSQMLMYPY 333
                F    ++H  + +  YP+
Sbjct: 179 KTE-TFVLSANLHGGALVASYPF 200


>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)

Query: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
           +YH  E + +++      +S +     IG S + +++ VL        H    P      
Sbjct: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80

Query: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
            +H  E +     +   + +V+  GKD  +T+++N+  I I    NPDGF      +   
Sbjct: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140

Query: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
            + R+N +          DLNRN+   F  N              +   +PE  A++ ++
Sbjct: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178

Query: 311 TAHGNFKALISIHSYSQMLMYPY 333
                F    ++H  + +  YP+
Sbjct: 179 KTE-TFVLSANLHGGALVASYPF 200


>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 30/203 (14%)

Query: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PAIWIDT 193
           +YH  E + +++      +S +     IG S + +++ VL        H    P      
Sbjct: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80

Query: 194 GIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMN--- 250
            +H  E +     +   + +V+  GKD  +T+++N+  I I    NPDGF      +   
Sbjct: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140

Query: 251 RLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI 310
            + R+N +          DLNRN+   F  N              +   +PE  A++ ++
Sbjct: 141 SIGRENYN--------QYDLNRNFPDAFEYN--------------NVSRQPETVAVMKWL 178

Query: 311 TAHGNFKALISIHSYSQMLMYPY 333
                F    ++H  + +  YP+
Sbjct: 179 KTE-TFVLSANLHGGALVASYPF 200


>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
          Length = 515

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/218 (24%), Positives = 88/218 (40%), Gaps = 25/218 (11%)

Query: 133 SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PA 188
           +F   S+H+  ++   +       + +     IG SF+ + +LV++FS+   +H    P 
Sbjct: 44  TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 103

Query: 189 IWIDTGIHSREWITHATGIWTANKIVSDY--GKDRVLTDILNAMDIFIELVTNPDGFAFT 246
           + +   IH  E       I+ A  + S+Y  G  R+   +LN   I +    NPDG+   
Sbjct: 104 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRI-QRLLNTTRIHLLPSMNPDGYEVA 162

Query: 247 HSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY-----HGPSPQS-- 299
            +    +    S R       +DLNRN    F    S     +ET      H P PQ   
Sbjct: 163 AAEGAGYNGWTSGRQN--AQNLDLNRN----FPDLTSEYYRLAETRGARSDHIPIPQHYW 216

Query: 300 ----EPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
                PE  AI+ ++     F    S+H    ++ YP+
Sbjct: 217 WGKVAPETKAIMKWMQTI-PFVLSASLHGGDLVVSYPF 253


>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
          Length = 641

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/218 (24%), Positives = 88/218 (40%), Gaps = 25/218 (11%)

Query: 133 SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PA 188
           +F   S+H+  ++   +       + +     IG SF+ + +LV++FS+   +H    P 
Sbjct: 170 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 229

Query: 189 IWIDTGIHSREWITHATGIWTANKIVSDY--GKDRVLTDILNAMDIFIELVTNPDGFAFT 246
           + +   IH  E       I+ A  + S+Y  G  R+   +LN   I +    NPDG+   
Sbjct: 230 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRI-QRLLNTTRIHLLPSMNPDGYEVA 288

Query: 247 HSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY-----HGPSPQS-- 299
            +    +    S R       +DLNRN    F    S     +ET      H P PQ   
Sbjct: 289 AAEGAGYNGWTSGRQN--AQNLDLNRN----FPDLTSEYYRLAETRGARSDHIPIPQHYW 342

Query: 300 ----EPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
                PE  AI+ ++     F    S+H    ++ YP+
Sbjct: 343 WGKVAPETKAIMKWMQTI-PFVLSASLHGGDLVVSYPF 379


>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
          Length = 652

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/218 (24%), Positives = 88/218 (40%), Gaps = 25/218 (11%)

Query: 133 SFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRH----PA 188
           +F   S+H+  ++   +       + +     IG SF+ + +LV++FS+   +H    P 
Sbjct: 181 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 240

Query: 189 IWIDTGIHSREWITHATGIWTANKIVSDY--GKDRVLTDILNAMDIFIELVTNPDGFAFT 246
           + +   IH  E       I+ A  + S+Y  G  R+   +LN   I +    NPDG+   
Sbjct: 241 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRI-QRLLNTTRIHLLPSMNPDGYEVA 299

Query: 247 HSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY-----HGPSPQS-- 299
            +    +    S R       +DLNRN    F    S     +ET      H P PQ   
Sbjct: 300 AAEGAGYNGWTSGRQN--AQNLDLNRN----FPDLTSEYYRLAETRGARSDHIPIPQHYW 353

Query: 300 ----EPEVAAIVNFITAHGNFKALISIHSYSQMLMYPY 333
                PE  AI+ ++     F    S+H    ++ YP+
Sbjct: 354 WGKVAPETKAIMKWMQTI-PFVLSASLHGGDLVVSYPF 390


>gi|4503493 early growth response 1 [Homo sapiens]
          Length = 543

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 36/123 (29%), Positives = 46/123 (37%), Gaps = 16/123 (13%)

Query: 277 GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHG-------NFKALISIHSYSQML 329
           G GG GSNS+  S T++  +   E         +TA         N K L+     SQ  
Sbjct: 71  GGGGGGSNSSSSSSTFNPQADTGEQPY----EHLTAESFPDISLNNEKVLVETSYPSQTT 126

Query: 330 MYP----YGRL-LEPVSNQRELMWPVGSPSTGPMTVASSTPSALSSGTLGSMASCCRPHR 384
             P     GR  LEP  N    +WP    S     V+ + P A SS      AS     +
Sbjct: 127 RLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQ 186

Query: 385 SSP 387
           S P
Sbjct: 187 SPP 189


>gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens]
          Length = 503

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 48/235 (20%)

Query: 128 ERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFST-----G 182
           E     F+Y   +T      ++D+    + D   + Q+G S + + + +L  ++      
Sbjct: 157 EEDIYQFAYCYPYTYTRFQHYLDSLQKRNMDYFFREQLGQSVQQRKLDLLTITSPDNLRE 216

Query: 183 GSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIF-IELVTNPD 241
           G+    ++I   +H  E  +        + +VS +    VL + L    +F I  + NPD
Sbjct: 217 GAEQKVVFITGRVHPGETPSSFVCQGIIDFLVSQHPIACVLREYL----VFKIAPMLNPD 272

Query: 242 GFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEP 301
           G    +    L             +G DLNR+W                    PSP   P
Sbjct: 273 GVYLGNYRCSL-------------MGFDLNRHWLD------------------PSPWVHP 301

Query: 302 EVAAIVNFITAHGN-----FKALISIHSYSQMLM-YPYGRLLEPVSN-QRELMWP 349
            +  +   I    N      +  I IH++S M+  + YG + E     QR+ ++P
Sbjct: 302 TLHGVKQLIVQMYNDPKTSLEFYIDIHAHSTMMNGFMYGNIFEDEERFQRQAIFP 356


>gi|239754026 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 422

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 15/34 (44%), Positives = 16/34 (47%)

Query: 365 PSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGP 398
           P  L     GS+     P RSSP PR RGW   P
Sbjct: 144 PHELHGQGRGSLTEPKEPRRSSPPPRERGWECRP 177


>gi|239748557 PREDICTED: hypothetical protein XP_002346722 [Homo
           sapiens]
          Length = 422

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 15/34 (44%), Positives = 16/34 (47%)

Query: 365 PSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGP 398
           P  L     GS+     P RSSP PR RGW   P
Sbjct: 144 PHELHGQGRGSLTEPKEPRRSSPPPRERGWECRP 177


>gi|239742540 PREDICTED: hypothetical protein XP_002342571 [Homo
           sapiens]
          Length = 422

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 15/34 (44%), Positives = 16/34 (47%)

Query: 365 PSALSSGTLGSMASCCRPHRSSPRPRRRGWRFGP 398
           P  L     GS+     P RSSP PR RGW   P
Sbjct: 144 PHELHGQGRGSLTEPKEPRRSSPPPRERGWECRP 177


>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
          Length = 1009

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 13/136 (9%)

Query: 261 PGIFCIG-VDLNRNWKSGFGGNGSNSN-------PCSETYHGPSPQSEPEVAAIVNFITA 312
           PG+   G  +L +    G G  G++S+       P S  + G +  S P    +    T 
Sbjct: 754 PGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTP 813

Query: 313 HGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELMWPVGSPSTGPMTVA-SSTPSALSSG 371
             +F    +   + Q  + P+     P         P+ S   GP     +S   A +SG
Sbjct: 814 QFSFPPAGTPTPFPQPPLNPF----VPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASG 869

Query: 372 TLGSMASCCRPHRSSP 387
            L S A  C PHRS P
Sbjct: 870 LLLSSAGFCAPHRSQP 885


>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 16/44 (36%), Positives = 20/44 (45%)

Query: 351 GSPSTGPMTVASSTPSALSSGTLGSMASCCRPHRSSPRPRRRGW 394
           GSP T P  VA    +  SS    +  +CC P R  PR    G+
Sbjct: 411 GSPKTSPKAVARRFTTRRSSSVDQARINCCVPPRIHPRSSIPGY 454


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 21/44 (47%), Positives = 21/44 (47%), Gaps = 10/44 (22%)

Query: 349 PVGSPSTGPMTVASSTPSALSSGTLGSMASCCRPHRSSPRPRRR 392
           P G   TGP       PSA SSG  G   S   P   SPRPRRR
Sbjct: 645 PDGEQPTGP-------PSATSSGADGPANS---PDGGSPRPRRR 678


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 13/70 (18%)

Query: 332 PYGRLLEPVSNQRELMWPVGSPSTGPMTVASSTPSALSSGTLGSMASCCRPHRSSPRPRR 391
           P+G  L PV NQ  ++ P G P T    VA+       SG +            +P P  
Sbjct: 109 PFGSPLAPVGNQPPVLQPYGPPPTSAQ-VATQLSGMQISGAV------------APAPPS 155

Query: 392 RGWRFGPSWS 401
            G  FGP  S
Sbjct: 156 SGLGFGPPTS 165


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,267,127
Number of Sequences: 37866
Number of extensions: 805564
Number of successful extensions: 2876
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2825
Number of HSP's gapped (non-prelim): 47
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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