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Search of human proteins with 186928827
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 830 0.0
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 819 0.0
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 797 0.0
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 784 0.0
gi|186928831 dermokine isoform 6 [Homo sapiens] 152 4e-37
gi|57864582 hornerin [Homo sapiens] 105 9e-23
gi|55956899 keratin 9 [Homo sapiens] 104 2e-22
gi|109255251 loricrin [Homo sapiens] 102 6e-22
gi|62122917 filaggrin family member 2 [Homo sapiens] 96 7e-20
gi|195972866 keratin 10 [Homo sapiens] 93 4e-19
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 91 2e-18
gi|119395750 keratin 1 [Homo sapiens] 87 3e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 87 3e-17
gi|47132620 keratin 2 [Homo sapiens] 86 8e-17
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 81 2e-15
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 81 2e-15
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 80 3e-15
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 80 4e-15
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 80 4e-15
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 78 2e-14
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 77 3e-14
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 77 3e-14
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 77 3e-14
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 77 3e-14
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 77 3e-14
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 75 8e-14
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 75 8e-14
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 75 1e-13
gi|89276766 trophinin isoform 5 [Homo sapiens] 75 1e-13
gi|48762934 alpha 2 type I collagen [Homo sapiens] 75 1e-13
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 830 bits (2144), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
Query: 361 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 819 bits (2115), Expect = 0.0
Identities = 398/416 (95%), Positives = 398/416 (95%), Gaps = 18/416 (4%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM--- 357
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
Query: 358 ---------------RNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
RNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 797 bits (2059), Expect = 0.0
Identities = 386/398 (96%), Positives = 386/398 (96%), Gaps = 12/398 (3%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ NS
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ------------NS 348
Query: 361 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 349 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 386
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 784 bits (2025), Expect = 0.0
Identities = 379/392 (96%), Positives = 380/392 (96%), Gaps = 12/392 (3%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ NS
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ------------NS 348
Query: 361 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQ 392
ETSPGMFNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 349 ETSPGMFNFDTFWKNFKSKLGFINWDAINKNQ 380
>gi|186928831 dermokine isoform 6 [Homo sapiens]
Length = 189
Score = 152 bits (385), Expect = 4e-37
Identities = 73/86 (84%), Positives = 74/86 (86%), Gaps = 12/86 (13%)
Query: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGM 366
GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ NSETSPGM
Sbjct: 20 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ------------NSETSPGM 67
Query: 367 FNFDTFWKNFKSKLGFINWDAINKDQ 392
FNFDTFWKNFKSKLGFINWDAINK+Q
Sbjct: 68 FNFDTFWKNFKSKLGFINWDAINKNQ 93
Score = 35.0 bits (79), Expect = 0.12
Identities = 31/142 (21%), Positives = 49/142 (34%), Gaps = 32/142 (22%)
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
G G + S+GS S N+G S GG +G G G+ G G SE+S
Sbjct: 15 GEGLEGSSTGSSS---GNHGGSGGG------NGHKPGCEKPGNEARGSGESGIQNSETSP 65
Query: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGM 366
G + + +S + ++ N ++ +
Sbjct: 66 GMFNFDTFWK-----------------------NFKSKLGFINWDAINKNQVPPPSTRAL 102
Query: 367 FNFDTFWKNFKSKLGFINWDAI 388
F W++FK F+NW AI
Sbjct: 103 LYFSRLWEDFKQNTPFLNWKAI 124
Score = 31.6 bits (70), Expect = 1.3
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 219 SVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-------SSGSGSNGDNNNGSSSG 270
S + + + EG S G SGGG+G + G + GSG +G N+ +S G
Sbjct: 8 SDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 66
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 105 bits (261), Expect = 9e-23
Identities = 108/367 (29%), Positives = 151/367 (41%), Gaps = 57/367 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAG------SKVSEA 70
G GE+ E S+G + + HG G S G G+ + + G S+ S
Sbjct: 1630 GLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
Query: 71 LGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127
GQ G+R++ G G RQ G G + + G H+ + H G G +
Sbjct: 1689 YGQHGSGSRQSSGHG-RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS--------GRSS 1739
Query: 128 VRGSWQGVPGHN---GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184
RG ++ GH+ G E+ GH SQ G G G + HG + +F
Sbjct: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF 1793
Query: 185 GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNS 244
+ +G+ GQ + G G++ + Q G GS ++ ++ GSG G S+S
Sbjct: 1794 --DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR-------HGSGSGHSSS 1844
Query: 245 GGGSGSQSG-SSGSGSNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSR 297
G GS SG SS SG +G + SS G SSS SSG + GS G S + G
Sbjct: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
Query: 298 GDSGSESSWGSSTGSSSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
G S GSS+GSSS HG G G+G P + G GSG+S
Sbjct: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSS 1963
Query: 346 QGFRGQG 352
G G G
Sbjct: 1964 YGPYGSG 1970
Score = 104 bits (259), Expect = 2e-22
Identities = 104/352 (29%), Positives = 147/352 (41%), Gaps = 50/352 (14%)
Query: 26 SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82
SG+ S+ + G GH G G S + G+ G ++GS G G+R++ G G
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
Query: 83 VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139
RQ G G + + G + H+ + H G G + RG ++ GH+
Sbjct: 2174 -RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 2224
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G E+ GH SQ G G G + HG + +F + +G+ GQ +
Sbjct: 2225 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSH 2276
Query: 200 GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSG 258
G G++ + Q G GS ++ ++ GSG G S+S G GS SG SS SG
Sbjct: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGR-------HGSGSGHSSSYGQHGSGSGWSSSSG 2329
Query: 259 SNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSRGDSGSESSWGSSTGS 312
+G + SS G SSS SSG + GS G S + G G S GSS+GS
Sbjct: 2330 RHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 2389
Query: 313 SSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
SS HG G G+G P + G GSG+S G G
Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYSPYGSG 2440
Score = 103 bits (257), Expect = 3e-22
Identities = 106/379 (27%), Positives = 143/379 (37%), Gaps = 53/379 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G + G++ + G + +LG+ H G + RHG
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170
+ + + S G G W +S G GS GLG GQ + G T
Sbjct: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ G G S SG S S S + +G SSG
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
GS SG SS G GSS S G GS S S HG G G+GH P
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
Query: 334 GNEARGSGESGIQGFRGQG 352
G GSG S G G G
Sbjct: 2186 GRHGSGSGHSSSHGQHGSG 2204
Score = 100 bits (249), Expect = 2e-21
Identities = 103/352 (29%), Positives = 145/352 (41%), Gaps = 50/352 (14%)
Query: 26 SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82
SG+ S+ + G GH G G S + G+ G ++GS G G+R++ G G
Sbjct: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 1233
Query: 83 VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139
RQ G G + + G H+ + H G G + RG ++ GH+
Sbjct: 1234 -RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 1284
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G E+ GH SQ G G G + HG + +F + +G+ GQ +
Sbjct: 1285 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSY 1336
Query: 200 GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSG 258
G G++ + G GS ++ ++ GSG G S+S G GS SG SS SG
Sbjct: 1337 GHRGSGSSQSSGYGRHGAGSGQSPSRGR-------HGSGSGHSSSYGQHGSGSGWSSSSG 1389
Query: 259 SNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGN---SGGSRGDSGSESSWGSSTGS 312
+G + SS G SSS SSG + GS G S + G G S GSS+GS
Sbjct: 1390 RHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 1449
Query: 313 SSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
SS HG G G+G P + G GSG+S G G
Sbjct: 1450 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYSPYGSG 1500
Score = 99.4 bits (246), Expect = 5e-21
Identities = 105/379 (27%), Positives = 141/379 (37%), Gaps = 53/379 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170
+ + + S G W +S G GS GLG GQ + G T
Sbjct: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ GSG S SG S S S + +G SSG
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
GS SG SS G GSS S G GS S S HG G G+G P
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGQSP---SR 2655
Query: 334 GNEARGSGESGIQGFRGQG 352
G G G S G G G
Sbjct: 2656 GRHGSGLGHSSSHGQHGSG 2674
Score = 99.0 bits (245), Expect = 7e-21
Identities = 109/380 (28%), Positives = 152/380 (40%), Gaps = 42/380 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------GQGQG---NPGGLGTPWV 173
+ + + S G W +S G GS GLG GQ G + G
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
Query: 174 HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE---GC 229
HG G+++G S GA GQ + G G++ + G GS ++ + G
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 230 TNPPPSGS-GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
P G G GS S S Q GS S+G ++ SSSG SSS S G SG SSG
Sbjct: 1606 RQSPSYGRHGSGSGRS--SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG- 1662
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSS--GNHG-GSGGGNGHKPGCEKPGNEARGSGESGI 345
G G G S GSS+ SSS G HG GS +GH G + GSG+S
Sbjct: 1663 -YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGH-------GRQGSGSGQSPS 1714
Query: 346 QGFRGQGVSSNMRNSETSPG 365
+G G G+ + + + G
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSG 1734
Score = 98.6 bits (244), Expect = 9e-21
Identities = 106/378 (28%), Positives = 142/378 (37%), Gaps = 52/378 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69
GSG G +G+ + G HG G S G G + G+ +G G+ S
Sbjct: 897 GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
Query: 70 ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125
G+R + Q G++ + G + +LG+ H G + RHG+
Sbjct: 957 YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGTP 171
+ + S G W +S G GS GLG GQ + G T
Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
Query: 172 WVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQ 225
HG + S G + Q + GQ G+G + G QG+ + PG+G + ++
Sbjct: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSSS 274
SGSG SS+ GSG S SG S S S + +G SSG
Sbjct: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
Query: 275 GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
GS SG SS G GSS S G GS S S HG G G+GH P G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGHSP---SRG 1246
Query: 335 NEARGSGESGIQGFRGQG 352
G G S G G G
Sbjct: 1247 RHGSGLGHSSSHGQHGSG 1264
Score = 98.2 bits (243), Expect = 1e-20
Identities = 108/401 (26%), Positives = 154/401 (38%), Gaps = 74/401 (18%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66
GSG G+ + + + G HG S G+ G+ + G+ S
Sbjct: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125
G G+ ++ +G + GFG + + G V + ++ G HE + + +HG+
Sbjct: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184
+ GH S GHG GS+ G +G+ G+ +G G+ S S
Sbjct: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
Query: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241
G + G+ GQ + G G+ + GYGS R+S++ P SGSG S
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
Query: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
S SG SG Q GSS S+ +GS+SG SSS G +SG SS SG
Sbjct: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
Query: 296 SR------------------------------GDSGSESSWGSSTGSSSGNHGGSGGGNG 325
S+ G GS S W SS G G+ G G G
Sbjct: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
Query: 326 HKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
HK G + G GSG S G+R G S + G
Sbjct: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
Score = 98.2 bits (243), Expect = 1e-20
Identities = 115/414 (27%), Positives = 160/414 (38%), Gaps = 69/414 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 231 ---NPPPS----GSGGGSSNSGGGSGSQSG--------SSGSGSNG-----DNNNGSSSG 270
+P PS GSG G S+S G GS SG SGSG + ++ +G SSG
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 271 GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2061
Query: 324 NGHKPGCEKPGNEAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365
+G PG + G+ +R GSG S G G G+ SS + E+S G
Sbjct: 2062 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115
Score = 97.8 bits (242), Expect = 1e-20
Identities = 116/413 (28%), Positives = 161/413 (38%), Gaps = 67/413 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
G G+ G ++ D G+ G+++ + G+ G Q+ RHG
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
Query: 125 ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175
A + RG GH+ ++ G + S G G G G G G + W
Sbjct: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
Query: 176 ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230
+ S S G+ GQ G + + + Q G GS ++ + +
Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
Query: 231 --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271
+P PS GSG G S+S G GSG +SGSS S G ++ +G SSG
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
Query: 272 SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G+
Sbjct: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
Query: 325 GHKPGCEKPGNEAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365
G PG + G+ +R GSG S G G G+ SS + E+S G
Sbjct: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645
Score = 97.1 bits (240), Expect = 3e-20
Identities = 114/414 (27%), Positives = 160/414 (38%), Gaps = 69/414 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G+ + G HG G S G G+ G+ S
Sbjct: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 231 ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270
+P PS GSG G S+S G GSG S SG S + ++ +G SSG
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 271 GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
Query: 324 NGHKPGCEKPGNEAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365
+G PG + G+ +R GSG S G G G+ SS + E+S G
Sbjct: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
Score = 96.7 bits (239), Expect = 3e-20
Identities = 113/402 (28%), Positives = 152/402 (37%), Gaps = 61/402 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69
GS G+ +GT+ + GH G G A G G G + G A+G S+
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 70 ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115
T + + G + + G + HA G H G
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
Query: 116 QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHG 175
Q+ RHG+ + R S G H S G G S G G Q G +
Sbjct: 902 QSPSYGRHGSGSGRSSSSG--RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959
Query: 176 YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS 235
+ S S G+ G + G G+ Q G GS ++ + + G
Sbjct: 960 HGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG-----RH 1014
Query: 236 GSGGGSSNSGG----GSG---------SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
GSG G S+S G GSG S SG S + ++ +G SSG GSSSG SS
Sbjct: 1015 GSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
Query: 283 -----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
G +SG SS G G S G S S GS + SSG +G G G+G PG + G+
Sbjct: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSGQSPGHGQRGS 1133
Query: 336 EAR----------GSGESGIQGFRGQGV--SSNMRNSETSPG 365
+R GSG S G G G+ SS + E+S G
Sbjct: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175
Score = 95.9 bits (237), Expect = 6e-20
Identities = 104/374 (27%), Positives = 143/374 (38%), Gaps = 43/374 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 1914 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1972 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSASGQSSS 2028
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 2078
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS----GSGGGSSNSGG 246
+G+ G+G + + G PG G +E + S GSG G S+ G
Sbjct: 2079 PSYGRHGSGSGRSSSSGQHG----PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2134
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
GS+SG S G +++GSSS GS S SSG GS SRG GS
Sbjct: 2135 QHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS---- 2190
Query: 307 GSSTGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG---VSSN 356
GS SS G HG GSG + P + G+ + GSG S G G S
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
Query: 357 MRNSETSPGMFNFD 370
++ TS FD
Sbjct: 2251 GQHGSTSGQSSTFD 2264
Score = 95.9 bits (237), Expect = 6e-20
Identities = 101/347 (29%), Positives = 148/347 (42%), Gaps = 46/347 (13%)
Query: 26 SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80
SG+ S+ G + G++ HG G S+ G G++ G+ S G G+R++
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
Query: 81 TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139
G R G G + + G + G HE Q+ +HG+ + GH
Sbjct: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198
S G+G GS+ G +G+ + G+ +G G+ S S G QG+ GQ +
Sbjct: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQ--------NEGCTNPPPSGSGGGSSNSGGGSGS 250
G G + Q G GS R+S++ + SGSG S+ S GSGS
Sbjct: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
Query: 251 -------QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
Q GS+ S+ + GSS+G SSS G S SSG G G G S S
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG--YGRHGAGSGQSLSH 2772
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
GS +G SS ++G G G+G G + G+ GSG+ G +G
Sbjct: 2773 GRHGSGSGQSS-SYGQHGSGSGQSSGYSQHGS---GSGQDGYSYCKG 2815
Score = 94.4 bits (233), Expect = 2e-19
Identities = 113/372 (30%), Positives = 151/372 (40%), Gaps = 33/372 (8%)
Query: 17 GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71
GSG + G Q G S ++ GE G G + S G + +++ G +GS S +
Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+G E+ G RQ +G R +GH G ++ R G + G
Sbjct: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
GH+ T G HG Q GQ G + HG + + +G QG+
Sbjct: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250
GQ + G + Q G GS +S+ + S G S SG SG S
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299
Q GS S S+G +GS SG GSSSG SSS G G S SSG+ G G
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
Query: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGC---EKPGNEARGSG--ESGI-QGFRGQGV 353
S S GSS+G SS +HG G G C E +A G G ESG QG+ G
Sbjct: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
Query: 354 SSNMRNSETSPG 365
+S +S+ G
Sbjct: 834 ASGHFSSQGRHG 845
Score = 94.4 bits (233), Expect = 2e-19
Identities = 114/378 (30%), Positives = 152/378 (40%), Gaps = 52/378 (13%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG S+ G G G G G++ G G+ S S G+R + Q
Sbjct: 682 SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
Query: 86 VPGFGAADALGNRVGEAAHALGN---TGHEIGRQAEDV------IRHGADAVRGSWQGVP 136
G++ L + G+ H G+ +GH GRQ +RHG+ + S G
Sbjct: 742 ---HGSSSGLSSSYGQ--HGSGSHQSSGH--GRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPG-GLGTPWVHGYPGNSAGSFGMNPQ-GAPWG 194
G + +S GH GS G G GQ G G G + G+++G F + G+ G
Sbjct: 795 GSGTSCSSSCGHYESGS-GQASGFGQHESGSGQG----YSQHGSASGHFSSQGRHGSTSG 849
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSGGGSSNSGGGS 248
Q + G + + + Q S AS + + S GSG G S S G
Sbjct: 850 QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG------GSSGGSSGNSGGSR-GDSG 301
GS SG S S + +G SSG SSSG SSG GS SS GSR G S
Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHK-SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
Query: 302 SESSWGSSTGSSSG------------NHGGSGGGNGHKPGCEKPGNEARGSGESGIQG-F 348
GSS+GSSS HG G G+G P + G GSG+S G +
Sbjct: 969 RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYGPY 1027
Query: 349 R-GQGVSSNMRNSETSPG 365
R G G SS+ E+ G
Sbjct: 1028 RSGSGWSSSRGPYESGSG 1045
Score = 92.0 bits (227), Expect = 8e-19
Identities = 102/372 (27%), Positives = 143/372 (38%), Gaps = 39/372 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 2384 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 2441
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 2442 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 2498
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 2499 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 2548
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 2606
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++GSSS GS S SSG GS SRG GS G
Sbjct: 2607 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS----GL 2662
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG---VSSNMR 358
SS G HG GSG + P + G+ + GSG S G G S +
Sbjct: 2663 GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2722
Query: 359 NSETSPGMFNFD 370
+ TS FD
Sbjct: 2723 HGSTSGQSSTFD 2734
Score = 90.5 bits (223), Expect = 2e-18
Identities = 103/340 (30%), Positives = 140/340 (41%), Gaps = 45/340 (13%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G + HG + S G + G+ + S G G+ ++ G G RQ
Sbjct: 2001 SGYGQHGSSSGHSSTHGQHGSAS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 2058
Query: 86 VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
G G + G R + RQ+ RHG+ + R S G G G E+S
Sbjct: 2059 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHGP-GLGESS 2105
Query: 146 GGHGIFGSQGGLGGQGQG-NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF 204
G FG GQ + G G+ GY G G + +G G +G +
Sbjct: 2106 G----FGHHESSSGQSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSS-SGSSSRY 2159
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGSNG 261
G + G+ G+G Q G + P G SG G S+S G GS GS S S G
Sbjct: 2160 GQHGSGSRQSSGHG-----RQGSGSGHSPSRGRHGSGSGHSSSHGQHGS--GSGRSSSRG 2212
Query: 262 --DNNNGSSS----GGSSSGSSSGGSSGGSSGG---SSGNSGGSRGDSGSESSWGSSTGS 312
++ +G SS S SG SS S GS G S G G + G S + GSSTG
Sbjct: 2213 PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 2272
Query: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
SS +HG G G+ G + GSG+S +G G G
Sbjct: 2273 SS-SHGQHGSGSSQS---SSYGQQGSGSGQSPSRGRHGSG 2308
Score = 88.6 bits (218), Expect = 9e-18
Identities = 101/372 (27%), Positives = 142/372 (38%), Gaps = 39/372 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G+
Sbjct: 974 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1032 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 1088
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 1138
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 1196
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++GSSS GS S SSG GS SRG GS G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS----GL 1252
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA------RGSGESGIQGFRGQG---VSSNMR 358
SS G HG GSG + P + G+ + GSG S G G S +
Sbjct: 1253 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312
Query: 359 NSETSPGMFNFD 370
+ TS FD
Sbjct: 1313 HGSTSGQSSTFD 1324
Score = 88.6 bits (218), Expect = 9e-18
Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + GLG HG G+ +G S P + G
Sbjct: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250
G G+ A +Q G GS +Q + G T+ S GS G S+S G GS
Sbjct: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
Query: 251 QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308
S SSG G +G + S S G S SS G G SG S G S+ SGS S
Sbjct: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
Query: 309 STGSSSGNHGGSGG 322
S + GGS G
Sbjct: 2812 YCKGGSNHDGGSSG 2825
Score = 88.2 bits (217), Expect = 1e-17
Identities = 104/342 (30%), Positives = 137/342 (40%), Gaps = 49/342 (14%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G + HG + S G + G+ + S G G+ ++ G G RQ
Sbjct: 1531 SGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 1588
Query: 86 VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
G G + G R + RQ+ RHG+ + R S G G +G E+S
Sbjct: 1589 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHG-SGLGESS 1635
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
G FG GQ HG S S G G+ GQ G
Sbjct: 1636 G----FGHHESSSGQSSSYSQ-------HG--SGSGHSSGYGQHGSRSGQSSRGERHGSS 1682
Query: 206 TNTQGAVAQPGYGSVRASN---QNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGS 259
+ + Q G GS ++S Q G P G SG G S+S G GS GS S S
Sbjct: 1683 SRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS--GSGRSSS 1740
Query: 260 NG--DNNNGSSS----GGSSSGSSSGGSSGGSSGG---SSGNSGGSRGDSGSESSWGSST 310
G ++ +G SS S SG SS S GS G S G G + G S + GSST
Sbjct: 1741 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1800
Query: 311 GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
G SS +HG G G+ G + GSG+S +G G G
Sbjct: 1801 GQSS-SHGQHGSGSSQS---SSYGQQGSGSGQSPSRGRHGSG 1838
Score = 88.2 bits (217), Expect = 1e-17
Identities = 105/364 (28%), Positives = 143/364 (39%), Gaps = 54/364 (14%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G + HG + S G + G+ + S G G+ ++ G G RQ
Sbjct: 2471 SGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-RQ 2528
Query: 86 VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
G G + G R + RQ+ RHG+ + R S G G +G E+S
Sbjct: 2529 GSGSGQSPGHGQRGSGS------------RQSPSYGRHGSGSGRSSSSGQHG-SGLGESS 2575
Query: 146 GGHGIFGSQGGLGGQGQG-NPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF 204
G FG GQ + G G+ GY G G + +G G +G ++
Sbjct: 2576 G----FGHHESSSGQSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGERHGSS-SGSSSHY 2629
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG---SGGGSSNSGGGSGSQSGSSGSGSNG 261
G + G+ G+G Q G P G SG G S+S G GS SG S S
Sbjct: 2630 GQHGSGSRQSSGHG-----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 2684
Query: 262 DNNNG---------SSSGGSSSGSSSGGSSG-----GSSGGSSGNS------GGSRGDSG 301
++ G S SG SS+ S G SG G G +SG S G S G S
Sbjct: 2685 ESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
Query: 302 SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSE 361
S GS + SSG +G G G+G G GSG+S G G G + S+
Sbjct: 2745 SYGHRGSGSSQSSG-YGRHGAGSGQS---LSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQ 2800
Query: 362 TSPG 365
G
Sbjct: 2801 HGSG 2804
Score = 86.7 bits (213), Expect = 3e-17
Identities = 82/303 (27%), Positives = 122/303 (40%), Gaps = 30/303 (9%)
Query: 64 GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122
G + S++ R G+G Q P +G G+ G+++ N H G Q+ +
Sbjct: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
H + + G G H S G+G GS+ G +G+ + G+
Sbjct: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
+ +GQ G+G + G QG+ ++ VR + + ++ GSG S
Sbjct: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
S G S SG + ++ +G SSG S GS SG SS GS+ S G GS
Sbjct: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSE 361
S SS G S G H G + PG+ RGSG SG GQ + R+S
Sbjct: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSG-SGQSPSSGQHGTGFGRSSS 451
Query: 362 TSP 364
+ P
Sbjct: 452 SGP 454
Score = 85.1 bits (209), Expect = 1e-16
Identities = 94/363 (25%), Positives = 135/363 (37%), Gaps = 42/363 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
GSG + + G++ +G+ + G D G + G+ G+ S + G +
Sbjct: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
++ GFG G G + H G++ H G + +HG+ + + S
Sbjct: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194
G + +S G GS G QG+ G V HG + S G + G
Sbjct: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
Query: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
+ G+G FG + G+ +Q G S S+Q GS G S+S G
Sbjct: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
S SG S S ++ + +SG GS SG S G GS S G GS
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
Query: 307 GSSTGSSSGNHG---GSGGGNGHKPGC-EKPGNEARGSGESGIQGFRGQGVSSNMRNSET 362
GS SSSG HG G G GHK + G GSG + G S +
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 363 SPG 365
G
Sbjct: 972 QHG 974
Score = 85.1 bits (209), Expect = 1e-16
Identities = 96/369 (26%), Positives = 137/369 (37%), Gaps = 31/369 (8%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 1444 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALG------NTGHE--------IGRQAEDVI 121
+ G + G + LG+R + + G ++GH Q+
Sbjct: 1502 GWSSSRGPYE-SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1560
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWVHGYPGNS 180
+HGA + + S G H S G+G GS G G GQ G +P + S
Sbjct: 1561 QHGASSGQSSSHGQ--HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG- 239
S G+ G+ G + + +Q G GS +S + + S G
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1678
Query: 240 -GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GSS+ Q GS S+G GS SG S S G G SS S G G G
Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS--SHGQHGSGSG 1736
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG--QGVSSN 356
S S + S +G SS G G+GH + G+ GSG QG G G SS
Sbjct: 1737 RSSSRGPYESRSGHSS-VFGQHESGSGHSSAYSQHGS---GSGHFCSQGQHGSTSGQSST 1792
Query: 357 MRNSETSPG 365
+S G
Sbjct: 1793 FDQEGSSTG 1801
Score = 82.4 bits (202), Expect = 7e-16
Identities = 104/397 (26%), Positives = 147/397 (37%), Gaps = 63/397 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-------HGLGDALSEGVGKAIGKEAGGAAGSKVSE 69
G G+ G +SG+ S G G + G HG G S G + G +G S
Sbjct: 490 GHGQHGS-RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH-----GSGSGQSPSP 543
Query: 70 ALGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR--QAEDVIRHG 124
+ G+ G+R++ G G G + + G + H+ G GH+ R Q+ +HG
Sbjct: 544 SRGRHESGSRQSSSYGPHGY-GSGRSSSRGPYESGSGHSSG-LGHQESRSGQSSGYGQHG 601
Query: 125 ADAVRGSWQGVPGHNGAWETS--------------GGHGIFGSQGGLGGQGQGNPGGLGT 170
+ + S G G +S G HG SQ GQ G +
Sbjct: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
Query: 171 PWVHGYPGNSAGSFGMNPQGAPW-----------GQGGNGGPPNFGTNTQGAVAQPGYGS 219
HG + S+G + G+ W GQ G + G+ +Q G GS
Sbjct: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-GSGQSSGYSQHGSGS 720
Query: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--GSSGSGSN---GDNNNGSSSG---- 270
+S + + SG S G SG S G GSGS+ G GS SG
Sbjct: 721 SHSSGYRKHGSR---SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPS 777
Query: 271 ----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
GSSSG SS GS S + G SG S +G S + G +GH
Sbjct: 778 RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGH 837
Query: 327 KPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETS 363
+ G+ + S SG Q G SS+ E++
Sbjct: 838 FSSQGRHGSTSGQSSSSG-QHDSSSGQSSSYGQHESA 873
Score = 80.9 bits (198), Expect = 2e-15
Identities = 95/345 (27%), Positives = 143/345 (41%), Gaps = 49/345 (14%)
Query: 56 GKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR 115
G+ G+ S ++ G G+ ++ G + + G G + H G+ GH G
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHK-------SSSGQSSGYSQHGSGS-GHSSGY 257
Query: 116 QAEDVIRHGADAVRGS-WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV- 173
+HG+ + + S + +G+ + G HG GS+ LG QG+ V
Sbjct: 258 G-----QHGSRSGQSSRGERHRSSSGSSSSYGQHGS-GSRQSLGHGRQGSGSRQSPSHVR 311
Query: 174 HGYPGNSAGSFGMNPQGAPWG------QGGNGGPPNFGTNTQGAVAQPGY-----GSVRA 222
HG + S G + G+ + + G+G FG + G+ GY GS +
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
Query: 223 SNQNE-GCTNPPPSGSG-GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG--------GS 272
S+Q + G T+ S SG GSS+ S Q S+ S+G + S SG GS
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431
Query: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG---SSTGSSSG--NHG-GSGGGNGH 326
SG S G+ G S +SG SG S +G SS+ SSG HG GSG +GH
Sbjct: 432 GSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGH 491
Query: 327 KPGCEKPGNEARG------SGESGIQGFRGQGVSSNMRNSETSPG 365
+ G +RG +G S G G G ++ +S G
Sbjct: 492 GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSG 536
Score = 60.5 bits (145), Expect = 3e-09
Identities = 61/182 (33%), Positives = 77/182 (42%), Gaps = 20/182 (10%)
Query: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNE--GCTNPPPSGSGG-GSSNSGGG 247
W G N ++ N +G++ +PG S+ R S Q + G N S G NS
Sbjct: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
Query: 248 SGSQSGSSGSGSNGDNN---NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
S G GSGS N +GS SG SSS + G SG SSG S S S G S S
Sbjct: 188 QSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKS--SSGQSSGYS 245
Query: 305 SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEAR-GSGESGIQGFRGQGVSSNMRNSETS 363
GS +G SSG G +G + G G R SG S G G G ++ +
Sbjct: 246 QHGSGSGHSSGY-----GQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
Query: 364 PG 365
G
Sbjct: 301 SG 302
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 104 bits (259), Expect = 2e-22
Identities = 76/211 (36%), Positives = 82/211 (38%), Gaps = 48/211 (22%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
GG F S G G G G GG G + G G S GS+G GG+GG
Sbjct: 460 GGQEDFESSGA-GKIGLGGRGGSGGSYGRGSRGGSGGSYG---------GGGSGG----- 504
Query: 206 TNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
G GGGS + GG GS G SGSG
Sbjct: 505 ------------------------------GYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
G SGG SG S GG SGGS G G SG G G S G S G+HGG G G
Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG 594
Query: 326 HKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G G EA GSG G G G G SS+
Sbjct: 595 ESGGSYGGGEEASGSG-GGYGG--GSGKSSH 622
Score = 84.0 bits (206), Expect = 2e-16
Identities = 60/142 (42%), Positives = 66/142 (46%), Gaps = 15/142 (10%)
Query: 235 SGSG----GGSSNSGG--GSGSQSGSSGS----GSNGDNNNGSSSGGSSSGSSSGGSSGG 284
SG+G GG SGG G GS+ GS GS GS G GS S G S GS GGS G
Sbjct: 468 SGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGS--G 525
Query: 285 SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG---SGGGNGHKPGCEKPGNEARGSG 341
S GGS G GG G S S G +G S GN+GG SGGG+G G G
Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585
Query: 342 ESGIQGFRGQGVSSNMRNSETS 363
G GF G+ S E S
Sbjct: 586 HGGGSGFGGESGGSYGGGEEAS 607
Score = 82.4 bits (202), Expect = 7e-16
Identities = 65/182 (35%), Positives = 79/182 (43%), Gaps = 14/182 (7%)
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+++ G + S G G G + G +G GS+GG GG G G G G G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGR-GSRGGSGGSYGGGGSGGGYGGGSGSRG 514
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
S GS+G G+ G GG G + G ++ G+ G G S N G GSG
Sbjct: 515 GSGGSYG-GGSGSGGGSGGGYGGGSGGGHSGGS----GGGHSGGSGGNYG------GGSG 563
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G SGGG G SGS G GS G + GS GG S GS GG SGG G G
Sbjct: 564 SGG-GSGGGYGGGSGSRG-GSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Query: 299 DS 300
S
Sbjct: 622 HS 623
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/129 (43%), Positives = 59/129 (45%), Gaps = 9/129 (6%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGS 296
SG G GG GS GS G GS G SGGS G SGG GG SG S G SGGS
Sbjct: 468 SGAGKIGLGGRGGS-GGSYGRGSRG------GSGGSYGGGGSGGGYGGGSG-SRGGSGGS 519
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G GS S GS G G+ GG GG+G GN GSG G G G S +
Sbjct: 520 YG-GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGS 578
Query: 357 MRNSETSPG 365
S S G
Sbjct: 579 RGGSGGSHG 587
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/154 (36%), Positives = 65/154 (42%), Gaps = 25/154 (16%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG----SSNSGGGSGS 250
+ G GG G+ GS+R+S + G GGG SS GGGS
Sbjct: 13 RSGGGGGGGLGSG----------GSIRSSYSRFSSSG---GGGGGGRFSSSSGYGGGSSR 59
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS------SGGSSGNSGGSRG--DSGS 302
G G GS G + G S GG S+ S GG GGS SGG +SGG G GS
Sbjct: 60 VCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGS 119
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336
+G GS G GG GGG G G NE
Sbjct: 120 GGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANE 153
Score = 68.9 bits (167), Expect = 7e-12
Identities = 53/127 (41%), Positives = 54/127 (42%), Gaps = 22/127 (17%)
Query: 236 GSGGG---------SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSGG SS GGG G S SSG G G GGS S GGS GG S
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFS 82
Query: 287 GGSSGNS--GGSRGDSG-SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
S G GGSRG G S + SS G G GGSGGG G GSG
Sbjct: 83 ASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGG----------GYGSGFG 132
Query: 344 GIQGFRG 350
G GF G
Sbjct: 133 GFGGFGG 139
Score = 65.1 bits (157), Expect = 1e-10
Identities = 53/131 (40%), Positives = 56/131 (42%), Gaps = 19/131 (14%)
Query: 236 GSGGGSSNSGGG---SGSQSGSSGSGSNGDNNNGSS------------SGGSSSGSSSGG 280
G GGG SGG S S+ SSG G G + SS GG S G S GG
Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGG 75
Query: 281 SSGGSSGGSS---GNSGGSRGDSG-SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336
SGG SS G GGSRG G S + SS G G GGSGGG G G G
Sbjct: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFG 135
Query: 337 ARGSGESGIQG 347
G G G G
Sbjct: 136 GFGGGAGGGDG 146
Score = 63.9 bits (154), Expect = 2e-10
Identities = 41/99 (41%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGS 308
+ G S+G G G S GS GS GGS G G G+ GG G SGS G
Sbjct: 459 EGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
Query: 309 STGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG 347
S G SG+ GGSGGG G G G G G SG G
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGS--GGGHSGGSG 555
Score = 60.5 bits (145), Expect = 3e-09
Identities = 53/129 (41%), Positives = 56/129 (43%), Gaps = 20/129 (15%)
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG--SSSGGSSGGSS-------GGSSGN 292
S SGGG G GS GS + + SS GG G SSS G GGSS GGS G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 293 S--GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG-------ES 343
S GGS G + S G G S G G SGGG G G GSG S
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGF--GGGFGGGSGGGFGGGYGS 129
Query: 344 GIQGFRGQG 352
G GF G G
Sbjct: 130 GFGGFGGFG 138
Score = 55.5 bits (132), Expect = 9e-08
Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 50/171 (29%)
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGNSA 181
++R S+ G GG G F S G GG G+G G G + Y G S
Sbjct: 27 SIRSSYSRFSSSGGG----GGGGRFSSSSGYGGGSSRVCGRGGGGSFG----YSYGGGSG 78
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G F + G +G G G FG SGGG
Sbjct: 79 GGFSASSLGGGFGGGSRG----FG-----------------------------GASGGGY 105
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
S+SGG G G SG G G G SG G GG+ GG G + N
Sbjct: 106 SSSGGFGGGFGGGSGGGFGG----GYGSGFGGFGGFGGGAGGGDGGILTAN 152
Score = 48.9 bits (115), Expect = 8e-06
Identities = 43/116 (37%), Positives = 48/116 (41%), Gaps = 15/116 (12%)
Query: 252 SGSSGSGSNGDNNNGSSSGG------SSSGSSSGGSSGGSSGGSSGNSGGS-----RGDS 300
S S S S G G SGG S SS GG GG SSG GGS RG
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 301 GSES-SWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
GS S+G +G S+S GG GGG+ G G + G G G G G
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGG 122
Score = 37.0 bits (84), Expect = 0.031
Identities = 36/132 (27%), Positives = 51/132 (38%), Gaps = 3/132 (2%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G G G ++ + GG G + S + G G + G FG + G+
Sbjct: 21 GLGSGGSIRSSYSR-FSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGI-FGSQGGLG 158
G +A +LG G G + G + G + G G GG+G FG GG G
Sbjct: 80 GFSASSLGG-GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFG 138
Query: 159 GQGQGNPGGLGT 170
G G GG+ T
Sbjct: 139 GGAGGGDGGILT 150
Score = 37.0 bits (84), Expect = 0.031
Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 17/141 (12%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G G G G G G G + G G G G GS + G G +
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGH 138
G+G G G+ G G G +G R G+ G G G
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYG------GGSGS----------RGGSGGSHGGGSGFGGE 595
Query: 139 NGAWETSGGHGIFGSQGGLGG 159
+G GG GS GG GG
Sbjct: 596 SGG-SYGGGEEASGSGGGYGG 615
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 2/79 (2%)
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
S G GG G GS S S SS G GG GG G + G G G G+
Sbjct: 14 SGGGGGGGLGSGGSIRSSYSRFSSSGG--GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 349 RGQGVSSNMRNSETSPGMF 367
G S ++ + G F
Sbjct: 72 SYGGGSGGGFSASSLGGGF 90
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 102 bits (254), Expect = 6e-22
Identities = 92/250 (36%), Positives = 99/250 (39%), Gaps = 57/250 (22%)
Query: 137 GHNGAWETSGGHGIFG---SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G G GG G FG S GG G G G GG GY G G G
Sbjct: 23 GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGG------GGYSGGGCG-------GGSS 69
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG----GGSSNSGGGSG 249
G GG GG G + G+V G G +S GC + GSG GG +SGGGSG
Sbjct: 70 GGGGGGGIGGCGGGSGGSVKYSGGGG--SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSG------SSSGGSSGGSSGGSSG--NSGGSRGD-- 299
S G S G + SS GG SG S G SSGGSSGG SG +SGG G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVC 187
Query: 300 ----SGSESSWGSSTGSSSG------------------NHGGSGGGNGHKPGCEKPGNEA 337
GS GSS GS SG G SGGG GC G
Sbjct: 188 GYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGG-- 245
Query: 338 RGSGESGIQG 347
G G SG G
Sbjct: 246 -GGGSSGCGG 254
Score = 93.6 bits (231), Expect = 3e-19
Identities = 88/268 (32%), Positives = 104/268 (38%), Gaps = 29/268 (10%)
Query: 89 FGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
FG + G G G G+ G G G G G G+ + SGG
Sbjct: 37 FGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG--GSGGSVKYSGGG 94
Query: 149 GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN- 207
G G G G G G + G G+S G G G GG G + G
Sbjct: 95 GSSGGGSGCFSSGGGGSGCFSS----GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150
Query: 208 -TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--SNSGGGSGSQSGSSGSGSNGDNN 264
+ AV YG V + + G + SG GGGS SGGGSG GSSG +G +
Sbjct: 151 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS 210
Query: 265 NG-----------SSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
+ S GGSS G SGGS SSGG G+SG G SG S S G S
Sbjct: 211 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS 270
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSG 341
G SGGG G G+ GSG
Sbjct: 271 VCGGGSSGGGGG--------GSSVGGSG 290
Score = 92.4 bits (228), Expect = 6e-19
Identities = 79/238 (33%), Positives = 95/238 (39%), Gaps = 26/238 (10%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGN---SA 181
G + G G+ GG GI G GG GG G G+ GG + G G+ S+
Sbjct: 57 GGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G G + G+ G GG G+ + G G ++ SG G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 242 SNSGGGSGSQSGSSGSGSN--GDNNNGSSSGGSSS----------------GSSSGGSSG 283
+SGGG GS G SG GS G ++ GS SG SS GSS GG SG
Sbjct: 177 FSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG 236
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG 341
GS SSG GGS G G S GS S G GG +G G G G G
Sbjct: 237 GSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 89.0 bits (219), Expect = 7e-18
Identities = 61/154 (39%), Positives = 65/154 (42%), Gaps = 18/154 (11%)
Query: 229 CTNPPPSGSGGGSSNSGG-----GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283
C G GGG S GG G GS GSSGSG G + G SGG G SSGG G
Sbjct: 16 CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGC-GYSGGGGYSGGGCGGGSSGGGGG 74
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSG-------GGNGHKPGCEKPGNE 336
G GG G SGGS SG S G +G S GGSG G +G GC G
Sbjct: 75 GGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG 134
Query: 337 ARGSGESGI-----QGFRGQGVSSNMRNSETSPG 365
G SG GF GQ V +S G
Sbjct: 135 GSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGG 168
Score = 89.0 bits (219), Expect = 7e-18
Identities = 81/226 (35%), Positives = 94/226 (41%), Gaps = 30/226 (13%)
Query: 143 ETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPP 202
+TSGG G GG GG G G GG G G G+ G G GG
Sbjct: 18 KTSGGGG---GGGGSGGGGCGFFGG--------------GGSGGGSSGSGCGYSGGGGYS 60
Query: 203 NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
G G+ G G + G + SGGG S+ GG SG GSG
Sbjct: 61 GGGCG-GGSSGGGGGGGIGGCGGGSGGS---VKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 263 NNNGSSSGGSSSGSS-SGGSSGGSSGGSSGNSGGSRGDSGSESSWG--SSTGSSSGNHG- 318
GSS GGS SS GGSSGG SG S GG G + S+G SS GSS G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 319 -GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETS 363
SGGG G G G+ G G G G G S+ + ++TS
Sbjct: 177 FSSGGGGGSVCGYSGGGSGCGG----GSSGGSGSGYVSSQQVTQTS 218
Score = 83.6 bits (205), Expect = 3e-16
Identities = 90/281 (32%), Positives = 108/281 (38%), Gaps = 29/281 (10%)
Query: 40 GHGLGDALSEGVGKAI---GKEAGGAAGSKVSEALGQG-TREAVGTGVRQVPGFGAADAL 95
G G G S G G G GG++GS + G G + G G G G
Sbjct: 21 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80
Query: 96 GNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
G G + G G G G + G G G + GG G F S G
Sbjct: 81 GGGSGGSVKYSGGGGSSGGGS-------GCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133
Query: 156 GL---GGQGQGNPGGLG----TPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF--GT 206
G GG G + GG G Y G S+G G GG G + G
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-----SQSGSSGSGSNG 261
+ G + G GS S+Q T+ P S GG S+ GGGSG S G GS G
Sbjct: 194 SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCG 253
Query: 262 DNNNGSSSGGSSSGSSS---GGSSGGSSGGSS-GNSGGSRG 298
++G SG SG S GGSSGG GGSS G SG +G
Sbjct: 254 GGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 37.4 bits (85), Expect = 0.024
Identities = 62/247 (25%), Positives = 79/247 (31%), Gaps = 70/247 (28%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEG---VGKAIGKEAGGAAGSKVSEAL 71
C SG G G + G + G G G S G G+A+ ++ G S S
Sbjct: 113 CFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG 172
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G + G G V G+ G+ G + +G+ +Q S
Sbjct: 173 GSGCFSSGGGG-GSVCGYSGG---GSGCGGGSSGGSGSGYVSSQQVTQT----------S 218
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
P + G +SGG GG GG G + GG G
Sbjct: 219 CAPQPSYGGG--SSGG-------GGSGGSGCFSSGGGG---------------------- 247
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G G GG G GS GC GG S+ GGG GS
Sbjct: 248 --GSSGCGG------------GSSGIGS--------GCIISGGGSVCGGGSSGGGGGGSS 285
Query: 252 SGSSGSG 258
G SGSG
Sbjct: 286 VGGSGSG 292
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 95.5 bits (236), Expect = 7e-20
Identities = 111/382 (29%), Positives = 155/382 (40%), Gaps = 53/382 (13%)
Query: 16 LGSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK--------AIGKEAGGAA- 63
LGSG++ +G G+ G++ G HG G S G G+ + G+ + G++
Sbjct: 572 LGSGQS----TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 627
Query: 64 -------GSKVSEALGQ-GTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIG 114
GS+ + GQ G+ + TG Q G G + G V + + G HE
Sbjct: 628 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESR 687
Query: 115 RQAEDVIRHGADAVRGSWQGVPGHN-GAWETSGGHGIFGSQG---GLGGQGQGNPGGLGT 170
+HG + + S G G + G G H + Q G G G G G G
Sbjct: 688 SGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQ 747
Query: 171 PWVHGYPGNSAGSFGMNPQGA---PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227
HG + FG + + +GQ +G + G G+ G+G + +
Sbjct: 748 ---HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 804
Query: 228 GCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSG--- 283
T GSG G S G GS SG SSG G + ++ SS G GS S SSG
Sbjct: 805 --TGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYG--QHGSGSSQSSGYGQ 860
Query: 284 -GSSGGSSGNSGGSRGDSGSESSW---GSSTGSSS--GNHG-GSGGGNG---HKPGCEKP 333
GSS G + G R SG S + GS +G SS G HG GSG +G H+ +
Sbjct: 861 HGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQS 920
Query: 334 GNEARGSGESGIQGFRGQGVSS 355
GSG S G+ G SS
Sbjct: 921 SYGQHGSGSSQSSGYGQHGSSS 942
Score = 92.8 bits (229), Expect = 5e-19
Identities = 109/385 (28%), Positives = 143/385 (37%), Gaps = 61/385 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKE---AGGAAGSKVSEALG 72
GSG + G+ +G+ G HG G S G G+ + + G GS S++ G
Sbjct: 798 GSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSG 857
Query: 73 QGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G+ Q GFG + G G H G+ Q+ +HG + G
Sbjct: 858 YGQH---GSSSGQTSGFGQHRSSSGQYSGFGQHGSGSG------QSSGFGQHGTGS--GQ 906
Query: 132 WQGVPGHNGAWETS--GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
+ G H S G HG SQ G GQ HG FG +
Sbjct: 907 YSGFGQHESRSHQSSYGQHGSGSSQSS--GYGQ-----------HGSSSGQTFGFGQHRS 953
Query: 190 GAPWGQG------GNGGPPNFGTNTQGAVAQPGYGS--VRASNQNEGCTNPPPSGSGGGS 241
G+ G G+G FG + G+ G+G R+S N G GSG
Sbjct: 954 GSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYG-----QHGSGSSQ 1008
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GSSGGSSGNSGG----- 295
S+ G GS SG + +++G SG GS S SSG G G SG S G
Sbjct: 1009 SSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYE 1068
Query: 296 --SRGDSGSESSWGSSTGSSSGNHGGSGGGNG----HKPGC-EKPGNEARGSGESGIQGF 348
SR S + GSS S G HG + G H+PG + G GSG GF
Sbjct: 1069 SRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGF 1128
Query: 349 ----RGQGVSSNMRNSETSPGMFNF 369
G G SS E G ++
Sbjct: 1129 GQHGSGTGKSSGFAQHEYRSGQSSY 1153
Score = 89.7 bits (221), Expect = 4e-18
Identities = 106/370 (28%), Positives = 150/370 (40%), Gaps = 55/370 (14%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G+ G G + LS G + G+ +GS S GQ G+G Q
Sbjct: 704 SGYGQHGSSSGQTSGFGQHE-LSSGQSSSFGQHG---SGSGQSSGFGQH-----GSGSGQ 754
Query: 86 VPGFGAADALGNRVGEAAHALGNT-----GHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
GFG ++ + H+ G++ G RQ +HG+ + + + G G +G
Sbjct: 755 SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SG 813
Query: 141 AWETSGGHGIFGSQGGLGGQGQG-------------NPGGLGTPWVHGYP--GNSAGS-- 183
+ +++G FG G GQ G G G+ GY G+S+G
Sbjct: 814 SGQSAG----FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869
Query: 184 -FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQNEGCTN 231
FG + Q + +GQ G+G + FG + G+ G+G S ++S G +
Sbjct: 870 GFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGS 929
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS 290
SG G S+SG G SGSG S+G +GS SG SS SG SSG
Sbjct: 930 SQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQ 989
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGG-----GNGHKPGCEKPGNEARGSGESGI 345
S S+ + G S GSS S G HG S G G + G GSG
Sbjct: 990 HESRSSQSNYGQHGS-GSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQS 1048
Query: 346 QGFRGQGVSS 355
GF G S
Sbjct: 1049 SGFGQHGTGS 1058
Score = 83.2 bits (204), Expect = 4e-16
Identities = 108/394 (27%), Positives = 165/394 (41%), Gaps = 67/394 (17%)
Query: 17 GSGEAGPLQS--GEESTGTNIGEALG-HGLGDALSEGVGK----AIGKEAGGAAGSKVSE 69
G+ E G Q+ G+ TG++ G +G G + S G+ + G+ + ++ ++ S+
Sbjct: 356 GARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSK 415
Query: 70 A--LGQGTREAV-----GTGVRQVPGF-----GAADALGNRVGEAAHALGNTGH-EIGRQ 116
G G+ ++ GTG+ Q GF G+ G ++ +LG H +
Sbjct: 416 CDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGK 475
Query: 117 AEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQG-----NPGGLGTP 171
+HG+ + + S G G +G+ ++SG FG G + GQ G + G +
Sbjct: 476 TSGFGQHGSGSGQSSGFGQCG-SGSGQSSG----FGQHGSVSGQSSGFGQHGSVSGQSSG 530
Query: 172 WVHGYPGNSAGSFGMNPQGAP----WGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227
+ + S+G + G+ +GQ G+ FG + G+ G+G
Sbjct: 531 FGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQY------- 583
Query: 228 GCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSG G S+ G GS SG SSG G + + SS G SSGSS SSG
Sbjct: 584 --------GSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ--SSGYGQ 633
Query: 287 GGSSGNSGGSRGDSGSESS-----WGSSTGSSSG---NHGGSGGGNG-----HKPGCEKP 333
GS SG + SGS S +GS +G SSG + GSG +G + G
Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSY 693
Query: 334 GNEARGSGESGIQGFRG--QGVSSNMRNSETSPG 365
G GS +S G G G +S E S G
Sbjct: 694 GQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSG 727
Score = 80.1 bits (196), Expect = 3e-15
Identities = 114/408 (27%), Positives = 166/408 (40%), Gaps = 88/408 (21%)
Query: 27 GEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG-GAAGSKVSEALGQGTREAVGT 81
G+ +G++ G HG + G G+ + G+ +G G GS ++ G G GT
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQH---GT 902
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNT--------GHEIGR------------QAEDVI 121
G Q GFG ++ ++ H G++ G G+ Q+
Sbjct: 903 GSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFG 962
Query: 122 RHGADAVRGSWQGVPGHNGAWETSG--GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN 179
+HG+ + + S G +G+ ++SG H SQ G G G+ G +G G+
Sbjct: 963 QHGSGSGQSSGFG-QHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG----YGQHGS 1017
Query: 180 SAGS---FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQ 225
S+G FG + Q + +GQ G+G + FG + G+ G+G S ++S
Sbjct: 1018 SSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYG 1077
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGG 284
G + SG G SNSG SG GSG S+G GS SG SS G +G
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGK 1137
Query: 285 SSG------------------GSSGNSGGSRGDSGS-------ESSWGSSTGSSSGNH-G 318
SSG GSS +SG + +SGS + GS SSSG H
Sbjct: 1138 SSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHIS 1197
Query: 319 GSGGGNGHKPGCEKPGNEARGSGES-GIQGFRGQGVSSNMRNSETSPG 365
SG G G GSG+S G+ GQG S + + T G
Sbjct: 1198 DSGQSTGF-------GQYGSGSGQSTGL----GQGESQQVESGSTVHG 1234
Score = 76.3 bits (186), Expect = 5e-14
Identities = 91/336 (27%), Positives = 124/336 (36%), Gaps = 36/336 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG------------ 60
GS G+ +G+ G HG G S G G+ GK +G
Sbjct: 939 GSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998
Query: 61 -GAAGSKVSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAE 118
G GS S++ G G G+ Q GFG + G G H G+ Q+
Sbjct: 999 YGQHGSGSSQSSGYGQH---GSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD------QSS 1049
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+HG + + S G + G HG SQ GQ N G H PG
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHR-PG 1108
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ S G G+ GQ G GT AQ Y S ++S G + SG G
Sbjct: 1109 SGQSS-GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG 1167
Query: 239 GGSSNSGGGSG---SQSGSSGSGSNGDN--NNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
S SG + SGS S+G + ++G S+G GS SG S+G G S
Sbjct: 1168 QHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVE 1227
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
GS E++ G + ++ H SG G + G
Sbjct: 1228 SGSTVHGRQETTHGQTINTT--RHSQSGQGQSTQTG 1261
Score = 70.5 bits (171), Expect = 3e-12
Identities = 95/355 (26%), Positives = 128/355 (36%), Gaps = 46/355 (12%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDALSE-GVGKAIGKEAGGAAGSKVSEALGQGTR 76
G +G QS + + T A GH D+ GV A G AGS+ E+ G
Sbjct: 2008 GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES-GSSVH 2066
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
E GT G HA G R + R G+ S V
Sbjct: 2067 ERHGT------------THGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV- 2113
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
H+G T GH ++ G G G GT +HG G++ GQ
Sbjct: 2114 -HSGVSHTHSGHTYGQARSQHGESGSAIHGRQGT--IHGQTGDTTRH----------GQS 2160
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G+G G+ T G S S+ +E + P+ SG S +G G QSGSSG
Sbjct: 2161 GHGQSTQTGSRTTGRQRS----SHSESSDSEVHSEASPTHSGHTHSQAGSRHG-QSGSSG 2215
Query: 257 SGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
G G + G ++ + G G + G G SG S SWGS T S
Sbjct: 2216 HGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRG-SGHSESSDSEVHSWGSHT--HS 2272
Query: 315 GNHGGSGGGNGHKPGCEKPGNEARGSGES------GIQGFRGQGVSSNMRNSETS 363
G+ G G +PG G G++ G G+ GQ + R+S S
Sbjct: 2273 GHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGY-GQSTQTGSRSSRAS 2326
Score = 63.9 bits (154), Expect = 2e-10
Identities = 103/410 (25%), Positives = 143/410 (34%), Gaps = 74/410 (18%)
Query: 25 QSGEE---STGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
+SGEE +G+N E GHG LS G+ + G E+ + LG + +
Sbjct: 218 ESGEEYESGSGSNSWERKGHG---GLSCGL-ETSGHESNSTQSRIREQKLGSSCSGSGDS 273
Query: 82 GVRQ-VPGFGAADALGNRVGEAA----HALGNTGHEI-----GRQAEDVIRHGADAVRGS 131
G R G+ + G ++ H G G++ G Q+ G V G
Sbjct: 274 GRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSG- 332
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW-----------VHGYPGNS 180
G P G E++ + SQ G G + G P G W +G G+
Sbjct: 333 --GQPSGCGQPESNPCSQSY-SQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQ 389
Query: 181 AGSFGMNPQGAPWGQGGNGGPPN-----------------FGTNTQGAVAQPGY-----G 218
+ S G + G+ G+ N N F + G G+ G
Sbjct: 390 SCSNGQHEYGS-CGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCG 448
Query: 219 SVRASNQNEGCTNPP--------PSGSGGGSSNSGGGSGSQSG----SSGSGSNGDNNNG 266
S + Q+E ++ SG G G GSG SG SGSG +
Sbjct: 449 SGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQH 508
Query: 267 SSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG---SGGG 323
S G SSG GS G S G + SR S + GSS S G +G SG G
Sbjct: 509 GSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFG 568
Query: 324 NGHKPGCEKPGNEARGSGESGIQGF----RGQGVSSNMRNSETSPGMFNF 369
+ G GSG GF G G SS E+ G ++
Sbjct: 569 QHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 618
Score = 53.9 bits (128), Expect = 2e-07
Identities = 83/360 (23%), Positives = 120/360 (33%), Gaps = 53/360 (14%)
Query: 24 LQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGV 83
+Q+G +TG G GV G AGS E+ G E GT
Sbjct: 1941 IQTGSRTTGRR-GSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES-GSSVHERHGT-- 1996
Query: 84 RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWE 143
G H G++GH Q + + GH+G
Sbjct: 1997 ----------THGQTADTTRH--GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSH 2044
Query: 144 TSGGH--GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGMNPQ--GAPWGQ 195
T GH G GSQ G G G HG G++ G + Q G+
Sbjct: 2045 THSGHAHGQAGSQHGESGSSVHERHGT----THGQTGDTTRHAHSGHGQSTQRGSRTAGR 2100
Query: 196 GGNGGPPNFGTNTQGAVAQPG----YGSVRASNQNEGCTNPPPSGSGGGSSN-------S 244
G+G + + V+ YG R+ + G G+ G + S
Sbjct: 2101 RGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQS 2160
Query: 245 GGGSGSQSGSSGSGSNGDNNNGSS------------SGGS-SSGSSSGGSSGGSSGGSSG 291
G G +Q+GS +G +++ SS SG + S S G SG S G G
Sbjct: 2161 GHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQG 2220
Query: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG-IQGFRG 350
+ G GD+ + +G + G+ G+GH + + SG IQG G
Sbjct: 2221 TTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAG 2280
Score = 51.2 bits (121), Expect = 2e-06
Identities = 104/446 (23%), Positives = 154/446 (34%), Gaps = 115/446 (25%)
Query: 17 GSGEAGPLQS--GEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG-GAAGSKVSE 69
G E+ QS G+ +G++ G HG + G G+ + G+ +G G GS +
Sbjct: 988 GQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQ 1047
Query: 70 ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVR 129
+ G G GTG Q GFG ++ + H G++ Q+ +HG+++
Sbjct: 1048 SSGFGQH---GTGSGQSSGFGQYESRSRQSSYGQHGSGSS------QSSGYGQHGSNS-- 1096
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLG------GQGQGNPGGLGTPWVHGYPGNSAGS 183
G G H S G G +GS G G G G G H Y + S
Sbjct: 1097 GQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQ---HEYRSGQS-S 1152
Query: 184 FGMNPQGAPWGQG------GNGGPPNFGTNTQGA------------------VAQPGYGS 219
+G + G+ G G+G +FG + G+ Q G GS
Sbjct: 1153 YGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGS 1212
Query: 220 VRASNQNEGCTNPPPSGSGGGS---------------SNSGGGSGSQSGS-------SGS 257
+++ +G + SGS S SG G +Q+GS S
Sbjct: 1213 GQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQ 1272
Query: 258 GSNGDNNNGS--SSGGSSSGSSSGGSSGGSSGGS----SGNSGGSRGDSG--SESSWGSS 309
N D+ S S S + GS SG + G + G RGD+ S G S
Sbjct: 1273 SENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQS 1332
Query: 310 TGSSSGNHGGSG------------GGNGHKPGCEKPGNEARGS----------------- 340
T + S G G H+P ++ + GS
Sbjct: 1333 TQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTY 1392
Query: 341 ---GESGIQGFRGQGVSSNMRNSETS 363
GE+ G G G S R S T+
Sbjct: 1393 GQTGEATGHGHSGHG-QSTQRGSRTT 1417
Score = 47.8 bits (112), Expect = 2e-05
Identities = 97/429 (22%), Positives = 144/429 (33%), Gaps = 107/429 (24%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK---AIGKEAGGAAGSKVSEA 70
GSG++ SG G+ G++ G HG G S G + G+ + G G+ S++
Sbjct: 1108 GSGQS----SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQS 1163
Query: 71 LGQGTREAVGTGV-----RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGA 125
G G E+ G+G + V G + G + ++ + G + G + G
Sbjct: 1164 SGCGQHES-GSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG---------------- 169
S V G ET+ G I ++ GQGQ G
Sbjct: 1223 SQQVESGSTVHGRQ---ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSE 1279
Query: 170 ---------TPWVHGYPGN---SAGSFGMNPQGAPWGQGGNG---GPPNFGTNTQGAVAQ 214
+ +H G+ +GS QG GQ G+ G G +TQ
Sbjct: 1280 VHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRT 1339
Query: 215 PG-----YGSVRASNQNEGCTNPPPS------------------------------GSGG 239
G + S + G ++ P S G
Sbjct: 1340 SGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSS-----SGGS----------SSGSSSGGSSGG 284
G +SG G +Q GS +G G ++ SS SGGS S G SG
Sbjct: 1400 GHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 285 SSGGSSGNSGGSRGDSGSESSW--GSST--GSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340
+ G G + G GD+ + + G ST GSS+ GSG G+
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519
Query: 341 ---GESGIQ 346
G+SG Q
Sbjct: 1520 HTHGQSGSQ 1528
Score = 47.4 bits (111), Expect = 2e-05
Identities = 92/367 (25%), Positives = 127/367 (34%), Gaps = 55/367 (14%)
Query: 19 GEAGPLQSGEES--------TGTNIGEALGH---GLGDALSEGVGKAIGKEAGGAAGSKV 67
G+AG ES T G+ GH G G + G G+ G + S
Sbjct: 1827 GQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSG-SSTTGRRRSGHSESSD 1885
Query: 68 SEALGQGTREAVGTGVRQVPG-FGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGAD 126
SE G+ G Q G +++ ++ + H G TG D HG
Sbjct: 1886 SEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTH--GQTG--------DTTEHGHP 1935
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN---SAGS 183
+ + Q G GH + G G + G HG G+ +GS
Sbjct: 1936 SHGQTIQ--TGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGH-----THGQAGSHYPESGS 1988
Query: 184 FGMNPQGAPWGQGGNG---GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG-SGG 239
G GQ + G G +TQ G RAS +E + SG S
Sbjct: 1989 SVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGR---RASGHSEYSDSEGHSGVSHT 2045
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
S ++ G +GSQ G SGS + +G++ G + + S G S + G RG
Sbjct: 2046 HSGHAHGQAGSQHGESGSSVH--ERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGS 2103
Query: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG-SGESGIQGFRGQGVSSNMR 358
SESS S + G S +GH G +AR GESG QG
Sbjct: 2104 GHSESS------DSEVHSGVSHTHSGHTYG------QARSQHGESGSAIHGRQGTIHGQT 2151
Query: 359 NSETSPG 365
T G
Sbjct: 2152 GDTTRHG 2158
Score = 45.4 bits (106), Expect = 9e-05
Identities = 92/390 (23%), Positives = 131/390 (33%), Gaps = 61/390 (15%)
Query: 17 GSGEAGPLQSGEESTGTN---IGEALGH---GLGDALSEGVGKAIGKEAGGAAGSKVSEA 70
GS P + E GT IG+ GH G G + G + G++ + S SE
Sbjct: 1603 GSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRG-SRTTGRQRSSHSESSDSE- 1660
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG------ 124
V +GV G++ G++ + Q D RH
Sbjct: 1661 --------VHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGL 1712
Query: 125 --ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
R + + GH+ ++ G G+ + G + G VH G G
Sbjct: 1713 TTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------- 235
G + A G+G G+ T G + G+ S + G + P S
Sbjct: 1773 QTGDTTRHA---HSGHGQSTQTGSRTTGRRSS-GHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828
Query: 236 -GSGGGSSNS-------------GGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
GS G S S G SG SQSG S +G + G G S S S
Sbjct: 1829 AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEV 1888
Query: 281 SSGGS---SGGSSGNSGGSRGDSGS-----ESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
SGGS SG + + G+S S + TG ++ HG G + G
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTT-EHGHPSHGQTIQTGSRT 1947
Query: 333 PGNEARGSGESGIQGFRGQGVSSNMRNSET 362
G RGSG S G S+ + T
Sbjct: 1948 TGR--RGSGHSEYSDSEGPSGVSHTHSGHT 1975
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/323 (24%), Positives = 109/323 (33%), Gaps = 31/323 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDAL-----SEGVGKAIGKEAGGAAGSKVSEALG 72
G+AG Q GE + + HG GD G G G GS SE+
Sbjct: 2052 GQAGS-QHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSD 2110
Query: 73 QGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSW 132
V + +G A + G A H T H Q D RHG S
Sbjct: 2111 SEVHSGV-SHTHSGHTYGQARSQHGESGSAIHGRQGTIHG---QTGDTTRHGQ-----SG 2161
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN---SAGSFGMNPQ 189
G G+ T + +P G H G+ +GS G Q
Sbjct: 2162 HGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH--THSQAGSRHGQSGSSGHGRQ 2219
Query: 190 GAPWGQGGNG---GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS-GSGGGSSNSG 245
G GQ G+ +G +TQ G R S +E + S GS S +
Sbjct: 2220 GTTHGQTGDTTRHAHYGYGQSTQRGSRTTGR---RGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 246 GGSGSQSGSSGSGSNG--DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G +GSQ GS +G + +G + + G S G S +G S + + S
Sbjct: 2277 GQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQST-QTGSRSSRASHFQSHSSER 2335
Query: 304 SSWGSSTGSSSGNHGGSGGGNGH 326
GSS G++G + GH
Sbjct: 2336 QRHGSSQVWKHGSYGPAEYDYGH 2358
Score = 43.1 bits (100), Expect = 4e-04
Identities = 89/379 (23%), Positives = 127/379 (33%), Gaps = 59/379 (15%)
Query: 40 GHGLGDALSE-GVGKAIGKEAGGAAGSKVSEAL-------GQGTREAVGTGVRQVPGFGA 91
GH G A S+ G ++I E G + + GQ T+ T R+ G
Sbjct: 1746 GHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSE 1805
Query: 92 -ADALGNR-VGEAAHALGNTGHEIGRQ---AEDVIRHGADAVRGSWQGVPGHNGAWETSG 146
+D+ G+ + H+ G+T + G Q +E ++ G GH+
Sbjct: 1806 YSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHS-----QS 1860
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA--------------- 191
GHG +Q G G+ G + + G S G A
Sbjct: 1861 GHGQ-STQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRH 1919
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSG-SGGGSSNSGGGS 248
G G G + G Q G + R S +E + PSG S S ++ G +
Sbjct: 1920 QTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQA 1979
Query: 249 GSQSGSSGS----------GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG------SSGN 292
GS SGS G D SG S ++G + G S G+
Sbjct: 1980 GSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGH 2039
Query: 293 SGGSRGDSG-----SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG 347
SG S SG + S G S S HG + G G G+ S G
Sbjct: 2040 SGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAG 2099
Query: 348 FRGQGVSSNMRNSETSPGM 366
RG G S +SE G+
Sbjct: 2100 RRGSG-HSESSDSEVHSGV 2117
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/301 (23%), Positives = 103/301 (34%), Gaps = 51/301 (16%)
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAA----HALGNTGHEIGRQ---AEDVIRHG 124
GQ T+ T RQ F +DA + V H+ T + G Q +E +
Sbjct: 1330 GQSTQTGSRTSGRQ--RFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHER 1387
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGG--LGGQGQGNPGGLGTPWVHGYPGNSAG 182
+ G GH + GHG +G G +G G+ + VH S G
Sbjct: 1388 HETTYGQTGEATGHGHS-----GHGQSTQRGSRTTGRRGSGHSESSDSE-VH-----SGG 1436
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
S Q GQ G+ G +G ++ G T G S+
Sbjct: 1437 SHRPQSQEQTHGQAGS---------QHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKST 1487
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--------SG 294
G S +G GSG + +++ SGGS + S GS G S + +
Sbjct: 1488 QRGS---STTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITH 1544
Query: 295 GSRGDSGSESSWG---------SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
G GD+ S G +TG +H S H G +P + G++G
Sbjct: 1545 GQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGS 1604
Query: 346 Q 346
Q
Sbjct: 1605 Q 1605
Score = 37.4 bits (85), Expect = 0.024
Identities = 57/229 (24%), Positives = 81/229 (35%), Gaps = 23/229 (10%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGA 191
+ PGH + S S+G G G+ G HG G G ++ G
Sbjct: 120 EDTPGHKSGYRHSSW-----SEGEEHGYSSGHSRGT-VKCRHGSNSRRLGRQGNLSSSGN 173
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G + G + G + G SV + ++ PS G SG GS S
Sbjct: 174 QEGSQKRYHRSSCGHSWSGGKDRHGSSSVEL-RERINKSHISPSRESGEEYESGSGSNSW 232
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES-SWGSST 310
+ G S G +SG S + G+S GDSG S + G S
Sbjct: 233 ERKG--------HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSN 284
Query: 311 GSSSGN-HGGSGGGNGHKPGCEKPGNE---ARGSGESGIQGFRGQGVSS 355
S G S H+ G + GN+ + +SGI+G +G G S
Sbjct: 285 SSGCGRPQNASSSCQSHRFGGQ--GNQFSYIQSGCQSGIKGGQGHGCVS 331
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 93.2 bits (230), Expect = 4e-19
Identities = 53/132 (40%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
Query: 227 EGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
EG + G GGGS G G GS G S G +G + GSS GG GSS GGSSGG
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Query: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
GG G+S G G S S G S+G G +GG G G G G + G +S
Sbjct: 514 GG--GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571
Query: 347 GFRGQGVSSNMR 358
G G+ S R
Sbjct: 572 GSVGESSSKGPR 583
Score = 91.3 bits (225), Expect = 1e-18
Identities = 56/131 (42%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+G +GG G + G GYG + + G G GGG S GG G G
Sbjct: 455 GEGSSGGGGRGGGSFGG-----GYGGGSSGGGSSG------GGHGGGHGGSSGG-GYGGG 502
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
SSG GS+G G SS G GSSSGG GGSSGG G GG GS S G GSS
Sbjct: 503 SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSS 562
Query: 314 SGNHGGSGGGN 324
SG H S G+
Sbjct: 563 SGGHKSSSSGS 573
Score = 84.3 bits (207), Expect = 2e-16
Identities = 55/127 (43%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G S+ GGG G GS G G G ++ G SSGG G GGSSGG GG S G S G
Sbjct: 455 GEGSSGGGGRG--GGSFGGGYGGGSSGGGSSGG-GHGGGHGGSSGGGYGGGSSGGGSSGG 511
Query: 299 DSGSESSWGSSTGSSSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G SS G GSSSG +GG SGGG G G G + G G G G SS+
Sbjct: 512 GYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571
Query: 357 MRNSETS 363
E+S
Sbjct: 572 GSVGESS 578
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/163 (36%), Positives = 68/163 (41%), Gaps = 41/163 (25%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GS GG GG+G G+ GG GY G S+G G + G G GG+ G
Sbjct: 457 GSSGG-GGRGGGSFGG-------GYGGGSSGG-GSSGGGHGGGHGGSSGG---------- 497
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYG SGGGSS G G GS SG G S+G GSS GG
Sbjct: 498 ----GYGG---------------GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 272 SSS---GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GSS GGSS G G +SGG + S SS G
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 41/162 (25%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
+SGG G G G GG G G+ GG G+S G G GG+GG
Sbjct: 458 SSGGGGRGGGSFG-GGYGGGSSGG----------GSSGGGHG----------GGHGGS-- 494
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN 263
+ GYG + + G G GG S+SGG GS SG G GS+G
Sbjct: 495 ---------SGGGYGGGSSGGGSSG-------GGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 264 NNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSE 303
G G S GSSSGG GG SSGG +S GS G+S S+
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580
Score = 76.3 bits (186), Expect = 5e-14
Identities = 60/137 (43%), Positives = 67/137 (48%), Gaps = 15/137 (10%)
Query: 219 SVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
SVR S+ ++ G GGG GGG S SS GS G G SSGG S GS S
Sbjct: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLG---GGFSSGGFSGGSFS 58
Query: 279 GGSSGGSS-GGSSGNSGGSRGDSGSESSWGSSTGSSS--GNHGGSGGGNGHKPGCEKPGN 335
GSSGG GGSSG GG G G S+ S GSSS G++GGS GG G
Sbjct: 59 RGSSGGGCFGGSSGGYGGLGGFGG--GSFRGSYGSSSFGGSYGGSFGGGSF-------GG 109
Query: 336 EARGSGESGIQGFRGQG 352
+ G G G GF G G
Sbjct: 110 GSFGGGSFGGGGFGGGG 126
Score = 73.6 bits (179), Expect = 3e-13
Identities = 57/127 (44%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 235 SGSGGGSSNSGGGSG-------SQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
SG GGG GGG G S GS G G S+G + GS S GSS G GGSSGG
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGG-Y 74
Query: 287 GGSSGNSGGS-RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
GG G GGS RG GS S GS GS G G G G G G G G G
Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGG- 133
Query: 346 QGFRGQG 352
GF G G
Sbjct: 134 -GFGGDG 139
Score = 62.8 bits (151), Expect = 5e-10
Identities = 53/166 (31%), Positives = 63/166 (37%), Gaps = 38/166 (22%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP-QGAPWGQGGNGGPPNFGTNTQGA 211
S GG GG G G GG+ + + G+ G F G + +G +GG
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG----------- 64
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
G GGSS GG G G S GS G ++ G S GG
Sbjct: 65 ------------------------GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGG 100
Query: 272 SSSGSS-SGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
S G S GGS GG S G G GG G G +G G SGN
Sbjct: 101 SFGGGSFGGGSFGGGSFGGGGFGGGGFG-GGFGGGFGGDGGLLSGN 145
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/141 (36%), Positives = 57/141 (40%), Gaps = 27/141 (19%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS--Q 251
G GG GG G G S+R S+ GS GG +SGG SG
Sbjct: 17 GGGGGGG---------GCGGGGGVSSLRISSSK---------GSLGGGFSSGGFSGGSFS 58
Query: 252 SGSSGSG-----SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS--SGNSGGSRGDSGSES 304
GSSG G S G G GGS GS S GGS GGS G+ GG GS
Sbjct: 59 RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118
Query: 305 SWGSSTGSSSGNHGGSGGGNG 325
G G G GG GG+G
Sbjct: 119 GGGFGGGGFGGGFGGGFGGDG 139
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 46/124 (37%)
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
G +G + GG+G S GG GG G GY G S+G G G
Sbjct: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSG-----------GYGGGSSGG----------GGG 540
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G GG + G ++ G G GG S+SGG S SGS G
Sbjct: 541 GYGGGSSGGGSSSG-------------------------GGYGGGSSSGGHKSSSSGSVG 575
Query: 257 SGSN 260
S+
Sbjct: 576 ESSS 579
Score = 39.3 bits (90), Expect = 0.006
Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 24/156 (15%)
Query: 46 ALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHA 105
+L EG G + G GG G G G+ +G G G + G G +
Sbjct: 451 SLLEGEGSSGG---GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSS--GGGYGGGSSG 505
Query: 106 LGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP 165
G++G G GS G GH G+ +SGG+G GS GG GG G
Sbjct: 506 GGSSGGGYGG--------------GSSSG--GHGGS--SSGGYG-GGSSGGGGGGYGGGS 546
Query: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGP 201
G G+ GY G S+ + G+ + GP
Sbjct: 547 SGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582
Score = 38.1 bits (87), Expect = 0.014
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG 347
GSSG GG RG S+G G S G SGGG+G G G GS G G
Sbjct: 457 GSSG--GGGRGGG----SFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
Query: 348 FRGQGVSSNMRNSETSPG 365
G SS+ + +S G
Sbjct: 511 GGYGGGSSSGGHGGSSSG 528
Score = 36.6 bits (83), Expect = 0.041
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 22/107 (20%)
Query: 145 SGGHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNS-AGSFGMNPQGAPWGQGGNGGPP 202
SGG GS GG G G GGLG G+ G S GS+G + G +G GG
Sbjct: 53 SGGSFSRGSSGGGCFGGSSGGYGGLG-----GFGGGSFRGSYGSSSFGGSYGGSFGGGSF 107
Query: 203 NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G+ G+ G+G G GGG GG G
Sbjct: 108 GGGSFGGGSFGGGGFGG---------------GGFGGGFGGGFGGDG 139
Score = 33.1 bits (74), Expect = 0.45
Identities = 28/80 (35%), Positives = 30/80 (37%), Gaps = 1/80 (1%)
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
SSS S SGG G GG G G S SS+ S G SGG +G G
Sbjct: 6 SSSKHYSSSRSGGG-GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64
Query: 336 EARGSGESGIQGFRGQGVSS 355
G G G G G S
Sbjct: 65 GCFGGSSGGYGGLGGFGGGS 84
Score = 32.7 bits (73), Expect = 0.59
Identities = 44/176 (25%), Positives = 56/176 (31%), Gaps = 58/176 (32%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G G G G S G + G GHG G S G G G GG++G
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGG--GHGGGHGGSSGGGYGGGSSGGGSSGG----------- 511
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
G+G + G HG + G G
Sbjct: 512 -----------GYGGGSSSGG-------------------------HGGSSSGGYGGGSS 535
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G GG+G GS GG G G GG + G+ +S+GS G + P
Sbjct: 536 GGGG-----GGYG-GGSSGGGSSSGGGYGGGSSS---GGHKSSSSGSVGESSSKGP 582
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS--AGSFGMNPQGAPWGQGGNGGP 201
+SGG+G G GG +G G + + G S GSFG G +G GG GG
Sbjct: 70 SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG----GGSFGGGGFGG- 124
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQ 225
FG G G G + + N+
Sbjct: 125 GGFGGGFGGGFG--GDGGLLSGNE 146
Score = 28.9 bits (63), Expect = 8.5
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 17/77 (22%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
G + RGS+ G G++ S G G FG GG G G GG G G
Sbjct: 81 GGGSFRGSY-GSSSFGGSYGGSFGGGSFG--GGSFGGGSFGGGGFG-----------GGG 126
Query: 184 FGMNPQGAPWGQGGNGG 200
FG G G GG+GG
Sbjct: 127 FG---GGFGGGFGGDGG 140
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/198 (33%), Positives = 83/198 (41%), Gaps = 26/198 (13%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
++GG+G S GQ PG P P +++GS+G + Q + +GQ P
Sbjct: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251
G+ +Q QP YG + S + NPP S SGGG GGG+ Q
Sbjct: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
S SSG GS G N SGG SG GG G SG GG G + SS G
Sbjct: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
Query: 312 SSSGNHGGSGGGNGHKPG 329
G GG GG G G
Sbjct: 243 GRGGGRGGRGGMGGSDRG 260
Score = 74.3 bits (181), Expect = 2e-13
Identities = 73/246 (29%), Positives = 87/246 (35%), Gaps = 39/246 (15%)
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP------QGAPW 193
GA+ T G G GQ Q G + GY +S S+G + Q P
Sbjct: 15 GAYPTQPGQGYSQQSSQPYGQ-QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ 73
Query: 194 GQGGNGGPPNFGTNTQGAVAQ----PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G G GG + ++Q + Q PGYG A + G S G SG S
Sbjct: 74 GYGSTGGYGS-SQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
Query: 250 SQSGSSGSGSNGDNNNGSSSGG--------SSSGSSSGG-------------SSGGSSGG 288
S S G + + G SSSG GG SSGG SGG
Sbjct: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
Query: 289 SSGN----SGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
GN GG G G + G G S G GG GGG G +P RG G G
Sbjct: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP--RGRGGGRGG 250
Query: 345 IQGFRG 350
G G
Sbjct: 251 RGGMGG 256
Score = 66.2 bits (160), Expect = 5e-11
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
G G GG+G+G P G G GY G +G G G P G GG GG G
Sbjct: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
Query: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269
P ++ S +NE C P P G GGG G G G G G + G
Sbjct: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G G GG GG GG G G + DS E
Sbjct: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/266 (24%), Positives = 85/266 (31%), Gaps = 29/266 (10%)
Query: 52 GKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
G+ +++ G + Q T + G G +G + G G+TG
Sbjct: 22 GQGYSQQSSQPYGQQSYSGYSQST-DTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGG 80
Query: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTP 171
Q+ + + G PG+ S G +GS GQ G
Sbjct: 81 YGSSQS-------SQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133
Query: 172 WVHGYPGNSAGS---------FGMNPQ--GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
+G S G +G Q + G GG GG N+G + + G G
Sbjct: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193
Query: 221 RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG----GSSSGS 276
+ G GSGG GG G G G G N SS G G G
Sbjct: 194 YGNQDQSG-----GGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248
Query: 277 SSGGSSGGSSGGSSGNSGGSRGDSGS 302
G GGS G GG R D GS
Sbjct: 249 GGRGGMGGSDRGGFNKFGGPR-DQGS 273
Score = 59.7 bits (143), Expect = 5e-09
Identities = 65/278 (23%), Positives = 95/278 (34%), Gaps = 39/278 (14%)
Query: 29 ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87
+ST T+ G++ G + + G G + G+ G S Q ++ + G P
Sbjct: 43 QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98
Query: 88 GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147
G+G A + G + ++ + GS+ P + G ++ G
Sbjct: 99 GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145
Query: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207
+ G G Q Q N G G G G++G + G G GG N +
Sbjct: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267
G GYG + G GSGGG GGG SG G G
Sbjct: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGGGGGGGGYNRSSG-------GYEPRGR 244
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G G G GG + GSR DS ++S
Sbjct: 245 GGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
Score = 50.4 bits (119), Expect = 3e-06
Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G+G + + G G GG G S ++ G G G + G G + G +
Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159
G +G G G G +G +E G G G +GG+GG
Sbjct: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
Query: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209
+G G P G +S N G G N + TN +
Sbjct: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
Query: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247
+ R + + +G + PPS G SG
Sbjct: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302
G +G G G G G GG S G GG SGG GG +G + +
Sbjct: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
Query: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347
SW + G G G GGN G + G ++ G RG G +G
Sbjct: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
Query: 348 FRGQG 352
RG G
Sbjct: 497 GRGGG 501
Score = 45.8 bits (107), Expect = 7e-05
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 14/140 (10%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GGNG G G + + GYG + G GG S GGG G Q
Sbjct: 379 GGNG---RGGRGRGGPMGRGGYGGGGSGG----------GGRGGFPSGGGGGGGQQRAGD 425
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS-GGSRGDSGSESSWGSSTGSSS 314
N N + S + G GG G+ GG+ GD G G
Sbjct: 426 WKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 315 GNHGGSGGGNGHKPGCEKPG 334
G G GG G + G ++ G
Sbjct: 486 GRGGDRGGFRGGRGGGDRGG 505
Score = 39.7 bits (91), Expect = 0.005
Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 29/183 (15%)
Query: 206 TNTQGAV-AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
T + GA QPG G + S+Q G S SG S G G QS S G + +
Sbjct: 11 TQSYGAYPTQPGQGYSQQSSQPYG----QQSYSGYSQSTDTSGYG-QSSYSSYGQSQNTG 65
Query: 265 NGSSSGGSSSGSSSGGSSGGSSGGSS----------------GNSGGSRGDSGSESSWG- 307
G+ S GS+ GG S SS ++ GS G S SS+G
Sbjct: 66 YGTQSTPQGYGST-GGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ 124
Query: 308 --SSTGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMRNSET 362
S + S ++GG G + P G + + + SG G G G + S
Sbjct: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184
Query: 363 SPG 365
S G
Sbjct: 185 SSG 187
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 87.0 bits (214), Expect = 3e-17
Identities = 53/129 (41%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS--SGNSG 294
SGGGS GGG GSS G +G GG SGGSS GS GGS SG G
Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGG 572
Query: 295 GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS 354
G G GS SS G G S G GGS GG G G RGS G+ + G S
Sbjct: 573 GGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGV---KSSGGS 629
Query: 355 SNMRNSETS 363
S+++ T+
Sbjct: 630 SSVKFVSTT 638
Score = 80.9 bits (198), Expect = 2e-15
Identities = 49/112 (43%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
GYGS +S + G + SG GGG GSG S SG GS G G G SG
Sbjct: 524 GYGSGGSSYGSGGGSYG--SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSG 581
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
SSSGG GGS GG G+SGG GS GSSSG SGG + K
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
Score = 79.7 bits (195), Expect = 4e-15
Identities = 55/136 (40%), Positives = 66/136 (48%), Gaps = 20/136 (14%)
Query: 175 GYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
G G G +G G+ +G GG ++G+ G + YGS +S
Sbjct: 516 GSRGGGGGGYGSG--GSSYGSGGG----SYGSGGGGGGGRGSYGSGGSSY---------- 559
Query: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
GSGGGS SGGG G GS GSGS+ G S GG S GS GGSSGGS G G
Sbjct: 560 -GSGGGSYGSGGGGGGH-GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617
Query: 295 GSRGDSGSESSWGSST 310
S G G +SS GSS+
Sbjct: 618 SSSG--GVKSSGGSSS 631
Score = 79.0 bits (193), Expect = 7e-15
Identities = 50/134 (37%), Positives = 61/134 (45%), Gaps = 7/134 (5%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G S G S S S+ + G S GG G SGGSS GS GGS G+ GG G
Sbjct: 488 GEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGG 547
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGH-------KPGCEKPGNEARGSGESGIQGFRGQ 351
GS S GSS GS G++G GGG GH G + G+ G G SG +G G
Sbjct: 548 GRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGG 607
Query: 352 GVSSNMRNSETSPG 365
++ +S G
Sbjct: 608 SSGGSIGGRGSSSG 621
Score = 76.6 bits (187), Expect = 4e-14
Identities = 52/130 (40%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-----SSGGSS 286
P S S S + G GS+ G G +G ++ GS G SG GG SGGSS
Sbjct: 499 PNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSS 558
Query: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
GS G S GS G G S+GS + SS G GGSGGG G G G + G G G +
Sbjct: 559 YGSGGGSYGSGGGGGGHGSYGSGS-SSGGYRGGSGGGGGGSSGGRGSGGGSSG-GSIGGR 616
Query: 347 GFRGQGVSSN 356
G GV S+
Sbjct: 617 GSSSGGVKSS 626
Score = 69.3 bits (168), Expect = 6e-12
Identities = 58/147 (39%), Positives = 67/147 (45%), Gaps = 33/147 (22%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G G G SGG +GS GG G G G GG G+ +G G+S GS G +
Sbjct: 516 GSRGGGGGGYGSGGSS-YGSGGGSYGSGGGGGGGRGS---YGSGGSSYGS-----GGGSY 566
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG GG G+GS + + + G GSGGG S GG GS G
Sbjct: 567 GSGGGGG---------------GHGSYGSGSSSGGYRG----GSGGGGGGSSGGRGSGGG 607
Query: 254 SSGSGSNGDNNNGSSSGG--SSSGSSS 278
SSG G GSSSGG SS GSSS
Sbjct: 608 SSGGSIGG---RGSSSGGVKSSGGSSS 631
Score = 61.6 bits (148), Expect = 1e-09
Identities = 37/102 (36%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
G GGGS +GGG GS+S + GS + + + GG SG G GG GG G G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 296 SRGDSGSESSWGSSTGS---SSGNHGGSGGGNGHKPGCEKPG 334
G G G +G G GG G G G+ P C G
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151
Score = 59.7 bits (143), Expect = 5e-09
Identities = 41/133 (30%), Positives = 48/133 (36%), Gaps = 8/133 (6%)
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
G + G + G + + + G GG S+ GGG GS G GS N
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVN 69
Query: 265 NGSSSG-------GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G S G GS GG GG G G GG G G GS G
Sbjct: 70 LGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGF 129
Query: 318 GGSG-GGNGHKPG 329
GG G GG G+ G
Sbjct: 130 GGGGFGGGGYGGG 142
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/124 (35%), Positives = 49/124 (39%), Gaps = 15/124 (12%)
Query: 241 SSNSG--GGSGSQSGSSGSGSNGDNNNGSS---SGGSSSGSSSGGSSGGSSGGSSG---- 291
SS SG G G SGS+G + SS SGG SS G GGS G G
Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
Query: 292 ---NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
N GGS+ S S + G G +GG G G G G G G G G GF
Sbjct: 66 SLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG---GFGGGGFGGGGIGGGGFGGF 122
Query: 349 RGQG 352
G
Sbjct: 123 GSGG 126
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/113 (32%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS-FGMNPQGAPWGQGGNGGPPNF 204
GG G FG+ GG G + N GG + + G GS FG G +G GG GG
Sbjct: 51 GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG---- 106
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG-GSGSQSGSSG 256
G G + G+G GSGGG GG G G G G
Sbjct: 107 GGFGGGGIGGGGFGGF---------------GSGGGGFGGGGFGGGGYGGGYG 144
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 1/95 (1%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-SGSQS 252
G GG G ++ V G S+ S G G GG GGG G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
G G G G GS GG G GG GG G
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 65 SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
S++S +V T + G G+ G G + G+ G G G
Sbjct: 491 SRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRG 550
Query: 125 ADAVRGSWQGVPGHN-GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
+ GS G G + G+ GGHG +GS GG +G GG G G GS
Sbjct: 551 SYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY-RGGSGGGG-----GGSSGGRGS 604
Query: 184 FGMNPQGAPWGQGGNGG 200
G + G+ G+G + G
Sbjct: 605 GGGSSGGSIGGRGSSSG 621
Score = 36.2 bits (82), Expect = 0.053
Identities = 35/109 (32%), Positives = 40/109 (36%), Gaps = 19/109 (17%)
Query: 263 NNNGSSSGGSSSGSSSG---------GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
+ +G SGG S S+G SS SGG G G GS + G S
Sbjct: 7 SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
Query: 314 SGNHGGS---------GGGNGHKPGCEKPGNEARGSGESGIQGFRGQGV 353
N GGS GGG G G G G G G GF G G+
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG-GGFGGGGI 114
Score = 35.4 bits (80), Expect = 0.091
Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 22/150 (14%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
SGE P S ST G G G G G G GS S G G R
Sbjct: 494 SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSG---GSSYGSGGGSYGSGGGGGGGRG 550
Query: 78 AVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPG 137
+ G+G G+ G + G+ G G + +G+ + G ++G G
Sbjct: 551 SYGSG-------------GSSYGSGGGSYGSGGGGGGHGS-----YGSGSSSGGYRGGSG 592
Query: 138 HNGAWETSG-GHGIFGSQGGLGGQGQGNPG 166
G + G G G S G +GG+G + G
Sbjct: 593 GGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 30.8 bits (68), Expect = 2.2
Identities = 36/134 (26%), Positives = 46/134 (34%), Gaps = 7/134 (5%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNR- 98
G+ G S G I + + S G G + G G FGA G+R
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGS---FGAGGGFGSRS 66
Query: 99 ---VGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
+G + + GR + +G G G G G GG G FGS G
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
Query: 156 GLGGQGQGNPGGLG 169
G G G GG G
Sbjct: 127 GGFGGGGFGGGGYG 140
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 22/147 (14%)
Query: 56 GKEAGGAAG--SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEI 113
G + G+AG + TR + G G R G + G G + +L N G
Sbjct: 15 GGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSK 74
Query: 114 GRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
G + G G G G GG G GG+GG G G
Sbjct: 75 SISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG----GGGIGGGGFG---------- 120
Query: 174 HGYPGNSAGSFGMNPQGAPWGQGGNGG 200
G+ G+ G FG G +G GG GG
Sbjct: 121 -GF-GSGGGGFG----GGGFGGGGYGG 141
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 86.7 bits (213), Expect = 3e-17
Identities = 88/308 (28%), Positives = 106/308 (34%), Gaps = 46/308 (14%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G++ +PG G + GE G+ G A DA +G PG GA
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPK-GDAG------APGAPGGKGDAGAPGERGPPGLAGA 691
Query: 142 WETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG---APWGQGG 197
GG G G +GG G G G PG GTP + G PG G P+G P G G
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751
Query: 198 NGGPPNFGTNTQ-------------------GAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
+G P G GA PG R S G T PP P+G
Sbjct: 752 DGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811
Query: 238 GGGSSNSG--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--------GSSGGSSG 287
G +G GG G + G G GGS G GS GG
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA 871
Query: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH-----KPGCEKPGNEARGSGE 342
+ G G GS + G S S G G G+ PG P +A GE
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931
Query: 343 SGIQGFRG 350
G G +G
Sbjct: 932 KGSPGAQG 939
Score = 80.1 bits (196), Expect = 3e-15
Identities = 97/348 (27%), Positives = 118/348 (33%), Gaps = 44/348 (12%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G GE GP G L G G A G G K G R
Sbjct: 394 GKGEMGP-------AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446
Query: 77 EAVG-TGVRQVPGFGAADALGNRVGE-AAHALGNTGHEIGRQAEDVIRHGADAVRGSW-- 132
G G+ VPG D GE A+ L E GA RG
Sbjct: 447 GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE----------RGAPGFRGPAGP 496
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
G+PG G G G G +G G G+ G PGG P + G PG+ G G
Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG---PGMRGMPGSPGGPGSDGKPGP 553
Query: 192 PWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG--GG 247
P QG +G GPP G QPG N+G P +G GG G G
Sbjct: 554 PGSQGESGRPGPPG----PSGPRGQPGVMGFPGPKGNDGA--PGKNGERGGPGGPGPQGP 607
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDSGS 302
G + G G G G + G +GG G +G G +GD+G+
Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA 667
Query: 303 ESS-WGSSTGSSSGNHG--GSGGGNGHKPGCEKPGNEARGSGESGIQG 347
+ G + G G G G G + G PG E G G +G G
Sbjct: 668 PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG-GKGAAGPPG 714
Score = 79.0 bits (193), Expect = 7e-15
Identities = 89/326 (27%), Positives = 114/326 (34%), Gaps = 34/326 (10%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G G + G +A G R PG A L G G E G+ A
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP-------GPEGGKGAAGP 712
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWV 173
A QG+PG G + G G G GG G G +G G +G P
Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 174 HGYPGNSA--GSFGM----NPQGAPWGQGGNGGPPNFG--TNTQGAVAQPGYGSVRASNQ 225
G PG+ G+ G+ P+G+P G+ G GPP G +PG R +
Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSP-GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG 831
Query: 226 NEGCTNPP-----PSGSG-GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG 279
+G PP P GSG G G G + G G+ G G S + G
Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891
Query: 280 GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG 339
S G G G + G++G+ S G S G G PG + P
Sbjct: 892 PPGPSGSPGKDGPPGPA-GNTGAPGSPGVSGPKGDAGQPGEKG----SPGAQGPPGAPGP 946
Query: 340 SGESGIQGFRGQGVSSNMRNSETSPG 365
G +GI G RG M SPG
Sbjct: 947 LGIAGITGARGLAGPPGMPGPRGSPG 972
Score = 75.1 bits (183), Expect = 1e-13
Identities = 98/352 (27%), Positives = 120/352 (34%), Gaps = 30/352 (8%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G+ A L+ G G N + G+ G+ G + E G
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP 479
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHA--LGNTGHEIGRQAEDVIRHGADAVRGS--W 132
A G R PGF GE A G G R A G D V G
Sbjct: 480 GAAGE--RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG--EPGRDGVPGGPGM 535
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+PG G + G G GSQG G G P G G P V G+PG G
Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595
Query: 192 PWGQGGNG--GPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
G GG G GPP N T QG G G ++G T PP G +GG
Sbjct: 596 RGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG------DKGDTGPPGPQGLQGLPGTGGP 649
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--------GSSGGSSG-GSSGNSGGSRG 298
G G GD + GG + G G+ G G G G GG +G
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGG-KG 708
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+G G++ G GG G PG + E G G G+ G G
Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLG-SPGPKGDKGEPGGPGADGVPGKDG 759
Score = 73.6 bits (179), Expect = 3e-13
Identities = 77/305 (25%), Positives = 104/305 (34%), Gaps = 37/305 (12%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVI--RHGADAVRGSWQGVPGHN 139
G+ PG R GE G TG G + E+ + +GA G +G PG
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEK----GETGAP-GLKGENGLPGENGAPGPMGP-RGAPGER 308
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G G G G+ G G GQ PG G P G+PG+ + P G+P G G
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQ--PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366
Query: 200 -----------------GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
GPP + G + G + + G PP G+
Sbjct: 367 QRGEPGPQGHAGAQGPPGPPGIN-GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
GG+G + G G +G + G S G G +G G+ G+
Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
G+ G + + G G G PG P +GE G G G MR
Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERG-APG---PAGPRGAAGEPGRDGVPG---GPGMRGM 538
Query: 361 ETSPG 365
SPG
Sbjct: 539 PGSPG 543
Score = 70.9 bits (172), Expect = 2e-12
Identities = 80/292 (27%), Positives = 100/292 (34%), Gaps = 60/292 (20%)
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG----QGNPGGLGTPWVHGYPG 178
+GA +RG G PG NGA G G G G G G G G G P +G PG
Sbjct: 422 NGAPGLRGG-AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG 480
Query: 179 NS-----------AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227
+ AG G+ + P G+ G GP +GA +PG V
Sbjct: 481 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP----AGPRGAAGEPGRDGVPGG---P 533
Query: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG--------GSSSGSSSG 279
G P S G GS G GSQ S G G + G G+
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 280 GSSGGSSG-------GSSGNSG-----------GSRGDSGSESSWG----SSTGSSSGNH 317
G GG G G +G +G G +GD+G G TG G +
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653
Query: 318 GGSG----GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
G G G+ PG +A GE G G G + +R PG
Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAG---APGLRGGAGPPG 702
Score = 68.9 bits (167), Expect = 7e-12
Identities = 68/232 (29%), Positives = 87/232 (37%), Gaps = 18/232 (7%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGM-NPQGA 191
G PG G G G G +G G QG G PG LG + G G AG GM P+G+
Sbjct: 912 GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG-LAGPPGMPGPRGS 970
Query: 192 PWGQG--GNGGPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P QG G G P N + +G G + + G P S G S GG
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030
Query: 248 SGSQSGSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G + + G+ G + G G + S G SG + + GSRG G +
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 306 WGSSTGSSSGNHGGSG-------GGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G +G G +G GN PG P + G G G RG
Sbjct: 1091 RGDK--GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140
Score = 65.9 bits (159), Expect = 6e-11
Identities = 71/249 (28%), Positives = 90/249 (36%), Gaps = 18/249 (7%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
+QG PG G SG G G+ G G G+ G G G P G PG G G P G
Sbjct: 199 YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG-PPGIKG--PAG 255
Query: 191 APWGQGGNGGPPNFGTNTQ-GAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG--G 246
P G G G N + G PG G P P G+ G G G
Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPG 315
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSES 304
+G++ GS+G G + S G GS G++G G RG+ G +
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375
Query: 305 SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE----ARG----SGESGIQGFRGQGVSSN 356
G+ GS GG G PG ARG +G +G G RG
Sbjct: 376 HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435
Query: 357 MRNSETSPG 365
++ PG
Sbjct: 436 KNGAKGEPG 444
Score = 62.4 bits (150), Expect = 7e-10
Identities = 116/429 (27%), Positives = 148/429 (34%), Gaps = 95/429 (22%)
Query: 17 GSGEAGPLQSGEEST-GTNIGEALGHGLGDALSEGVGKAIGKEAG--GAAGSKVSEALGQ 73
G G+AG GE G L G G EG GK G GAAG+ + +
Sbjct: 673 GKGDAGA--PGERGPPGLAGAPGLRGGAGPPGPEG-GKGAAGPPGPPGAAGTPGLQGM-P 728
Query: 74 GTREAVGT----GVRQVPGFGAADALGNRVGEAAHA--LGNTGHEIGRQAEDVIRHGADA 127
G R +G+ G + PG AD + + G +G G Q D GA
Sbjct: 729 GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP--AGQPGDKGEGGAPG 786
Query: 128 VRG--SWQGVPGHNGAWETSGGHGIFGS---QGGLGGQGQ----GNPGGLGTPWVHGYPG 178
+ G +G PG G G G G+ G GG+G+ G G G P V G PG
Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
S + PQG +G GGP GA PG + + G PP PSGS
Sbjct: 847 GSGPAGPPGPQGVKGERGSPGGP--------GAAGFPGARGLPGPPGSNGNPGPPGPSGS 898
Query: 238 GG-----------------------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
G G + G GS G+ G +G
Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 275 GSSSG-----GSSG-----GSSG--GSSGNSG--------------GSRGDSGSESSWGS 308
G GS G G SG G++G SG G+ G+ G + + GS
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018
Query: 309 -STGSSSGNHGGSG-----------GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G+ GG G G GH PG P A SG+ G G G +
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAPGAPGH-PGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077
Query: 357 MRNSETSPG 365
S +PG
Sbjct: 1078 PAGSRGAPG 1086
Score = 56.2 bits (134), Expect = 5e-08
Identities = 81/282 (28%), Positives = 99/282 (35%), Gaps = 42/282 (14%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
GA+ + G +G PG G +G G G G G G PG G+P G G +
Sbjct: 984 GANGLSGE-RGPPGPQGLPGLAGTAGEPGRDGNPGSDGL--PGRDGSPGGKGDRGENGS- 1039
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSS 242
GAP G G+ GPP G V G R + G P P+GS G
Sbjct: 1040 -----PGAP-GAPGHPGPP-------GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086
Query: 243 NSG-----GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--GSSG--------GSSG 287
G G +G + + G G N + G G GS G G SG
Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
G G SG G G G + G S H G G G PG PG G G +
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG-PPGA--PGPCCGGVGAA 1203
Query: 344 GIQGFRGQ--GVSSNMRNSETSPGMFNFDTFWKNFKSKLGFI 383
I G G+ G + E N D + KS G I
Sbjct: 1204 AIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQI 1245
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/215 (26%), Positives = 69/215 (32%), Gaps = 10/215 (4%)
Query: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
GQG G G P G PG + G+P G G + T Q Q V
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDV 160
Query: 221 RASNQNEGCTN-PPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSS 277
++ G P P+G G G + G GS G G+ SG +
Sbjct: 161 KSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGA 220
Query: 278 SGGSSGGSSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
G S G SG G G G G + G H G G NG K
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280
Query: 333 PGNEARGS--GESGIQGFRGQGVSSNMRNSETSPG 365
PG + GE+G G G + R PG
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPG 315
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 85.5 bits (210), Expect = 8e-17
Identities = 52/125 (41%), Positives = 64/125 (51%), Gaps = 13/125 (10%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
GSGG S+SGGG S S S GSG + G S GG S S G SGG SGG G+ GG
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI-SGGGYGSGGGSGGRYGSGGG 578
Query: 296 SRGDSGSESSWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
S+G S S +GS G S G+ GGS G G+ G G G S ++G G+
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG---------GGGSSSVKGSSGEA 629
Query: 353 VSSNM 357
S++
Sbjct: 630 FGSSV 634
Score = 79.3 bits (194), Expect = 6e-15
Identities = 54/130 (41%), Positives = 64/130 (49%), Gaps = 17/130 (13%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GG+GG +G+ + GY S +S + G + GSGGG S SGGG GS GS
Sbjct: 519 GGSGG--------RGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSG 570
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSG 315
G +G GGS GS SGG G S GG + GGSRG S S +GS G SS
Sbjct: 571 GRYGSG--------GGSKGGSISGGGYG-SGGGKHSSGGGSRGGSSSGGGYGSGGGGSSS 621
Query: 316 NHGGSGGGNG 325
G SG G
Sbjct: 622 VKGSSGEAFG 631
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/122 (39%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SS S++ GSG G ++ G S GSSS SGG GS GGS G S G
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSS-YGSGGRQSGSRGGSGGGGSISGGGY 563
Query: 301 GSESSWGSSTGSSSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMR 358
GS G GS G+ GG SGGG G G G +RG SG G G SS+++
Sbjct: 564 GSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVK 623
Query: 359 NS 360
S
Sbjct: 624 GS 625
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/147 (37%), Positives = 65/147 (44%), Gaps = 38/147 (25%)
Query: 155 GGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQ 214
GG GG+G + GG + G+S+ G G+ G GG G +++
Sbjct: 519 GGSGGRGSSSGGGYSS-------GSSSYGSGGRQSGSRGGSGGGG-----------SISG 560
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYGS S G SGGGS S SGGG GS G SG G S GG
Sbjct: 561 GGYGSGGGSGGRYG--------SGGGSKGGSISGGGYGSGGGKHSSG-------GGSRGG 605
Query: 272 SSSGSSSGGSSGGSSG--GSSGNSGGS 296
SSSG G GGSS GSSG + GS
Sbjct: 606 SSSGGGYGSGGGGSSSVKGSSGEAFGS 632
Score = 58.2 bits (139), Expect = 1e-08
Identities = 58/188 (30%), Positives = 75/188 (39%), Gaps = 23/188 (12%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+GG GG G ++ AV G R S + C + GGG GGG GS+S
Sbjct: 11 GRGGGGGGFR-GFSSGSAVVS---GGSRRSTSSFSCLS---RHGGGGGGFGGGGFGSRSL 63
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
GG+ S S S GG G ++G GG G G SS+G +G S
Sbjct: 64 VG-------------LGGTKSISISVAGGGGGFG-AAGGFGGRGGGFGGGSSFGGGSGFS 109
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEA--RGSGESGIQGFRGQGVSSNMRNSETSPGMFNFDT 371
G GG G G G G PG G G G G+ G ++ S P D
Sbjct: 110 GGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDP 169
Query: 372 FWKNFKSK 379
+N K++
Sbjct: 170 EIQNVKAQ 177
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/117 (35%), Positives = 50/117 (42%), Gaps = 5/117 (4%)
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR-GDSGS 302
SG S + + S S + N ++ G S G S G SSG SS SGG + G G
Sbjct: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGG 551
Query: 303 ESSWGSSTGSSSGNHGGSGG----GNGHKPGCEKPGNEARGSGESGIQGFRGQGVSS 355
GS +G G+ GGSGG G G K G G G G+ G G SS
Sbjct: 552 SGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSS 608
Score = 53.1 bits (126), Expect = 4e-07
Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 137 GHNGAWETSGGHGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G G +SGG GS G GG+ G+ GG G G S G G G+
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGG-------GGSISGGGYGSGGGSGGR 572
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
G+GG G+ + G GYGS + + G + S SGGG + GGGS S GSS
Sbjct: 573 YGSGGGSKGGSISGG-----GYGSGGGKHSSGGGSRGG-SSSGGGYGSGGGGSSSVKGSS 626
Query: 256 G 256
G
Sbjct: 627 G 627
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 145 SGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ-----GAPWGQGGNG 199
+GG G FG+ GG GG+G G GG G+ G G G G P G GG G
Sbjct: 77 AGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
Query: 200 GPPNFG 205
GP FG
Sbjct: 137 GPGGFG 142
Score = 39.3 bits (90), Expect = 0.006
Identities = 48/180 (26%), Positives = 55/180 (30%), Gaps = 37/180 (20%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQG 74
C G G G G + G A+ G G S + + GG G G G
Sbjct: 7 CKSRGRGG---GGGGFRGFSSGSAVVSG-GSRRSTSSFSCLSRHGGGGGG------FGGG 56
Query: 75 TREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQG 134
G G R + G G ++ V G G GR
Sbjct: 57 -----GFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGG----------------- 94
Query: 135 VPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194
G G GG G G G GG G G GG G P G G G G P G P G
Sbjct: 95 --GFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGP---GGVGGLGGPGGFGPGGYPGG 149
Score = 35.8 bits (81), Expect = 0.070
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCE 331
S GG GG G SSG++ S G S SS+ + G G GGG G +
Sbjct: 6 SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVG 65
Query: 332 KPGNEA-------RGSGESGIQGFRGQG 352
G ++ G G GF G+G
Sbjct: 66 LGGTKSISISVAGGGGGFGAAGGFGGRG 93
Score = 34.7 bits (78), Expect = 0.16
Identities = 39/146 (26%), Positives = 53/146 (36%), Gaps = 30/146 (20%)
Query: 38 ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGN 97
A G G S G G + G + G+ G + G G ++ G G+G+ G
Sbjct: 517 AFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGG-----GYGSGGGSGG 571
Query: 98 RVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGL 157
R G + G + + G G G G +SGG GS G
Sbjct: 572 RYGSGGGSKGGS------------------ISG---GGYGSGGGKHSSGGGSRGGSSSG- 609
Query: 158 GGQGQGNPGGLGTPWVHGYPGNSAGS 183
GG G G G G+ V G G + GS
Sbjct: 610 GGYGSG---GGGSSSVKGSSGEAFGS 632
Score = 28.9 bits (63), Expect = 8.5
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 9/87 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSE-ALGQGT 75
GSG G + G G G G G G G G +GG GS + + G G+
Sbjct: 551 GSGGGGSISGG--------GYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEA 102
R +G G G + ++ GEA
Sbjct: 603 RGGSSSGGGYGSGGGGSSSVKGSSGEA 629
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 479
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 540 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 575
Score = 73.6 bits (179), Expect = 3e-13
Identities = 57/168 (33%), Positives = 68/168 (40%), Gaps = 18/168 (10%)
Query: 194 GQGGNGGPPN-FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
G+GG GG +G + G GYG R+S G + SG G G SGGG G
Sbjct: 404 GRGGRGGDRGGYGGDRSGG----GYGGDRSSG---GGYSGDRSGGGYGGDRSGGGYGGDR 456
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGGSRGD-SGSESSWGSST 310
G G G G GG GG GG GG G GG RG G +G
Sbjct: 457 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR 516
Query: 311 GS-----SSGNHGGS-GGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
G S G +GG GGG+G+ G ++ G G G RG G
Sbjct: 517 GGYGGDRSRGGYGGDRGGGSGY--GGDRSGGYGGDRSGGGYGGDRGGG 562
Score = 72.0 bits (175), Expect = 9e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 462
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 463 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 512
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 572
Query: 299 DSGSESSW 306
G + +
Sbjct: 573 KMGGRNDY 580
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/225 (31%), Positives = 88/225 (39%), Gaps = 43/225 (19%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206
G G G +G G G+G G GY G+ +G GG GG + G
Sbjct: 393 GRGYGGERGYRGRGGRGGDRG-------GYGGDRSG-------------GGYGGDRSSGG 432
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN- 265
G + GYG R+ G GG + GGG G G G G GD
Sbjct: 433 GYSGDRSGGGYGGDRSGGGYGG------DRGGGYGGDRGGGYG---GDRGGGYGGDRGGY 483
Query: 266 GSSSGGSSSGSSSG-----GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG- 319
G GG G G G GG GG G+ GG GD S +G G SG +GG
Sbjct: 484 GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSG-YGGD 541
Query: 320 -SGGGNGHKPGCEKPGNEARGSGESGIQGFRG--QGVSSNMRNSE 361
SGG G + G G+ RG G G +G G G ++ RN +
Sbjct: 542 RSGGYGGDRSGGGYGGD--RGGGYGGDRGGYGGKMGGRNDYRNDQ 584
Score = 67.4 bits (163), Expect = 2e-11
Identities = 57/205 (27%), Positives = 68/205 (33%), Gaps = 34/205 (16%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 326 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
Query: 236 ---------------------GSGGGSSNSGGGSGSQSG-------SSGSGSNGDNNNGS 267
G GG + GG G +SG SSG G +GD + G
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
G S G G GG G G GG RG G G G G +GG GG G
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGGGYGGDRGGYGGD 501
Query: 328 PGCEKPGNEARGSGESGIQGFRGQG 352
G G G G R +G
Sbjct: 502 RGGYGGDRGGYGGDRGGYGGDRSRG 526
Score = 52.4 bits (124), Expect = 7e-07
Identities = 65/248 (26%), Positives = 92/248 (37%), Gaps = 50/248 (20%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
+ Q + +Q Y +NQ + N SGS GG S + G
Sbjct: 65 GGYENQKQSSYSQQPY-----NNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 118
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 119 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 178
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG----IQGF 348
GG RG G + G TGSS G+ GG GH+ + ++ +QG
Sbjct: 179 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGL 238
Query: 349 RGQGVSSN 356
G+GVS++
Sbjct: 239 -GEGVSTD 245
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 417 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 474
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 475 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 530
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 531 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 584
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/160 (31%), Positives = 55/160 (34%), Gaps = 44/160 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 316 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 375
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 376 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQG 347
G S G +GG SGGG G G G+ RG G G +G
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGGYGGD--RGGGYGGDRG 473
Score = 35.4 bits (80), Expect = 0.091
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 1/97 (1%)
Query: 269 SGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
S S G S G S+ G+ G+ G + S S S +G +T SS G + G
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQA-SQSYSGYGQTTDSSYGQNYSGYSSYGQSY 60
Query: 329 GCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
G E + Q + QG NM +S + G
Sbjct: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGG 97
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 13/83 (15%)
Query: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGS-------SSGN-----HGGSGGGNGHKPGC 330
GG SGG GG RG G + G S GN N +P
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
Query: 331 EKP-GNEARGSGESGIQGFRGQG 352
+P G + RG G G +G+RG+G
Sbjct: 384 SRPSGGDFRGRGYGGERGYRGRG 406
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 482
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 543 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 578
Score = 73.6 bits (179), Expect = 3e-13
Identities = 57/168 (33%), Positives = 68/168 (40%), Gaps = 18/168 (10%)
Query: 194 GQGGNGGPPN-FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
G+GG GG +G + G GYG R+S G + SG G G SGGG G
Sbjct: 407 GRGGRGGDRGGYGGDRSGG----GYGGDRSSG---GGYSGDRSGGGYGGDRSGGGYGGDR 459
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGGSRGD-SGSESSWGSST 310
G G G G GG GG GG GG G GG RG G +G
Sbjct: 460 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDR 519
Query: 311 GS-----SSGNHGGS-GGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
G S G +GG GGG+G+ G ++ G G G RG G
Sbjct: 520 GGYGGDRSRGGYGGDRGGGSGY--GGDRSGGYGGDRSGGGYGGDRGGG 565
Score = 72.0 bits (175), Expect = 9e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 465
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 466 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 515
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 575
Query: 299 DSGSESSW 306
G + +
Sbjct: 576 KMGGRNDY 583
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/225 (31%), Positives = 88/225 (39%), Gaps = 43/225 (19%)
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGT 206
G G G +G G G+G G GY G+ +G GG GG + G
Sbjct: 396 GRGYGGERGYRGRGGRGGDRG-------GYGGDRSG-------------GGYGGDRSSGG 435
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN- 265
G + GYG R+ G GG + GGG G G G G GD
Sbjct: 436 GYSGDRSGGGYGGDRSGGGYGG------DRGGGYGGDRGGGYG---GDRGGGYGGDRGGY 486
Query: 266 GSSSGGSSSGSSSG-----GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG- 319
G GG G G G GG GG G+ GG GD S +G G SG +GG
Sbjct: 487 GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSG-YGGD 544
Query: 320 -SGGGNGHKPGCEKPGNEARGSGESGIQGFRG--QGVSSNMRNSE 361
SGG G + G G+ RG G G +G G G ++ RN +
Sbjct: 545 RSGGYGGDRSGGGYGGD--RGGGYGGDRGGYGGKMGGRNDYRNDQ 587
Score = 67.4 bits (163), Expect = 2e-11
Identities = 57/200 (28%), Positives = 72/200 (36%), Gaps = 32/200 (16%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 329 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
Query: 236 ---------------------GSGGGSSNSGGGSGSQSGSS--GSGSNGDNNNGSSSGGS 272
G GG + GG G +SG G S+G +G SGG
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
Query: 273 SSGSSSGGSSGGSSGGSSG--NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
G SGG GG GG G GG GD G +G G G+ GG GG+ G
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG--GGYGGDRGGYGGDRGGGYGGDRGGYGG 503
Query: 331 EKPGNEARGSGESGIQGFRG 350
++ G G G +G G
Sbjct: 504 DRGGYGGDRGGYGGDRGGYG 523
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/248 (26%), Positives = 92/248 (37%), Gaps = 47/248 (18%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +G
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
++G Q Y +NQ + N SGS GG S + G
Sbjct: 65 QSYGGYENQK--QSSYSQQPYNNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 121
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 122 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 181
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG----IQGF 348
GG RG G + G TGSS G+ GG GH+ + ++ +QG
Sbjct: 182 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGL 241
Query: 349 RGQGVSSN 356
G+GVS++
Sbjct: 242 -GEGVSTD 248
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 420 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 477
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 478 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 533
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 534 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 587
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/160 (31%), Positives = 55/160 (34%), Gaps = 44/160 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 319 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 378
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 379 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSGESGIQG 347
G S G +GG SGGG G G G+ RG G G +G
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGGYGGD--RGGGYGGDRG 476
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 13/83 (15%)
Query: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGS-------SSGN-----HGGSGGGNGHKPGC 330
GG SGG GG RG G + G S GN N +P
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
Query: 331 EKP-GNEARGSGESGIQGFRGQG 352
+P G + RG G G +G+RG+G
Sbjct: 387 SRPSGGDFRGRGYGGERGYRGRG 409
Score = 30.4 bits (67), Expect = 2.9
Identities = 32/122 (26%), Positives = 41/122 (33%), Gaps = 23/122 (18%)
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
S GS QSG + N GS G +S S SG S SG
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG--------Y 53
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETS 363
SS+G S S ++G G E + Q + QG NM +S +
Sbjct: 54 SSYGQSQSGYSQSYG---------------GYENQKQSSYSQQPYNNQGQQQNMESSGSQ 98
Query: 364 PG 365
G
Sbjct: 99 GG 100
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 80.1 bits (196), Expect = 3e-15
Identities = 68/193 (35%), Positives = 82/193 (42%), Gaps = 31/193 (16%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
GS +G G +G + GG+ FG GG G+G GN GG G GY G GS G
Sbjct: 211 GSQRGRGGGSGNFMGRGGN--FGGGGGNFGRG-GNFGGRG-----GYGGGGGGSRGS--- 259
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
+G GG+GG FG + PGY S G G G N GGG G
Sbjct: 260 ---YG-GGDGGYNGFGGDGGNYGGGPGYSSRGGYG-----------GGGPGYGNQGGGYG 304
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309
G G +G N G+ GG+ G + G SG N G +G S S GS
Sbjct: 305 -----GGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSP 359
Query: 310 TGSSSGNHGGSGG 322
G G+ GGSGG
Sbjct: 360 YGGGYGSGGGSGG 372
Score = 72.0 bits (175), Expect = 9e-13
Identities = 65/196 (33%), Positives = 81/196 (41%), Gaps = 37/196 (18%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GSQ G GG G GN G G G+FG G +G+GGN G +G
Sbjct: 211 GSQRGRGG-GSGNFMGRG------------GNFGGG--GGNFGRGGNFGG-------RGG 248
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-SQSGSSGSGSNGDNNNGSSSG 270
G GS + +G N G GG N GGG G S G G G G N G G
Sbjct: 249 YGGGGGGSRGSYGGGDGGYN----GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYG 304
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN--GHKP 328
G GG G + GG+ G GG+ G G+ + +G+ +G N+G GG+ G
Sbjct: 305 G------GGGYDGYNEGGNFG--GGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSS 356
Query: 329 GCEKPGNEARGSGESG 344
G G G G G
Sbjct: 357 GSPYGGGYGSGGGSGG 372
Score = 65.5 bits (158), Expect = 8e-11
Identities = 44/122 (36%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGG 295
S G GGGSG+ G G+ G N G GG+ G GG GGS G G GG
Sbjct: 209 SAGSQRGRGGGSGNFMGRGGNFGGGGGNFGR--GGNFGGRGGYGGGGGGSRGSYGGGDGG 266
Query: 296 SRGDSGSESSWGSSTG-SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVS 354
G G ++G G SS G +GG G G G++ G G G E G G G
Sbjct: 267 YNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGG 326
Query: 355 SN 356
N
Sbjct: 327 GN 328
Score = 58.2 bits (139), Expect = 1e-08
Identities = 65/212 (30%), Positives = 84/212 (39%), Gaps = 37/212 (17%)
Query: 51 VGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTG 110
V KA+ K+ +AGS+ G G+ +G G G G GN G + G G
Sbjct: 198 VKKALSKQEMQSAGSQ--RGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGG 255
Query: 111 HEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGT 170
D +G G++ G PG++ GG +G+QGG G G GG
Sbjct: 256 SRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGG----GYGGGGG--- 308
Query: 171 PWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT 230
GY N G+FG G +G GGN +FG S Q +
Sbjct: 309 --YDGY--NEGGNFG----GGNYGGGGNYN--DFG---------------NYSGQQQSNY 343
Query: 231 NPPPSGSGGGSSNS---GGGSGSQSGSSGSGS 259
P GS GG S+ GGG GS GS G GS
Sbjct: 344 GPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 375
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHG 318
S + + S G GS + GG+ GG GN G G+ G +G G S G++G
Sbjct: 203 SKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG-GNFGGRGGYGGGGGGSRGSYG 261
Query: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
G GG G GN G G S G+ G G
Sbjct: 262 GGDGGYNGFGG--DGGNYGGGPGYSSRGGYGGGG 293
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGSSTGSSS 314
+G N + S S S G GGS G GN GG G+ G ++G
Sbjct: 192 NGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFG------- 244
Query: 315 GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
G G GGG G + + G G+ G GF G G
Sbjct: 245 GRGGYGGGGGGSR--------GSYGGGDGGYNGFGGDG 274
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 79.7 bits (195), Expect = 4e-15
Identities = 70/248 (28%), Positives = 88/248 (35%), Gaps = 16/248 (6%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL----GTPWVHGYPGNSAGSFGMN 187
+ G+ G G +G G GS G G GQ P GL G P G P + G+ G
Sbjct: 270 FSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG-PAGARGNDGAT 328
Query: 188 PQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P G G GPP F GA + G R S +G P G++ G
Sbjct: 329 GAAGPPGPTGPAGPPGF-PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDSGS 302
G+ G+NG + G + SG G G GNSG GS+GD+G+
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447
Query: 303 ESSWG----SSTGSSSGNHGGSGG-GNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM 357
+ G +G G G G G P E G G G G G
Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGP 507
Query: 358 RNSETSPG 365
SPG
Sbjct: 508 AGERGSPG 515
Score = 73.9 bits (180), Expect = 2e-13
Identities = 97/352 (27%), Positives = 126/352 (35%), Gaps = 56/352 (15%)
Query: 52 GKAIGKEAGGAAGSKVSEALGQGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALG 107
G A + A GA G+ ++ G A G+ G++ +PG A L G+ A G
Sbjct: 692 GPAGPRGANGAPGNDGAKG-DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA-G 749
Query: 108 NTGHEIGRQAEDVIRHGADAVRGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPG 166
G + G +D +R + G PG G SG G G++G G +G+ P
Sbjct: 750 PKGAD-GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808
Query: 167 G----LGTPWVHGYPG--NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
G G P G PG G G P G G GPP G V PG
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG----PIGNVGAPGAKGA 864
Query: 221 RASNQNEGCTN----------PPPSGSGG-----GSSNSGGGSGSQSGSSGSGSNGDNNN 265
R S G T P PSG+ G G + GG G + + +G G+
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSS 314
G + S G + G+ G G G RG+ G G S
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS--GEP 982
Query: 315 GNHGGSG-GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
G G SG G PG P A GESG +G G +E SPG
Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG---------AEGSPG 1025
Score = 69.3 bits (168), Expect = 6e-12
Identities = 69/253 (27%), Positives = 89/253 (35%), Gaps = 23/253 (9%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSAGSFG 185
QG+PG GA G G G G G G +G G +G P G PG+ S
Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786
Query: 186 MNP------QGAPWGQGGNGGPPNFG-TNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
P +GAP +G G P G GA QPG +G PP P+G
Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846
Query: 238 GG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
G G + G G++ +G G ++G SG + G +G GG
Sbjct: 847 AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906
Query: 296 S--RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGV 353
RG++G G G G PG + P G GI G RG
Sbjct: 907 KGPRGETGPAGRPGEVGPPGPPGPAGEKGS----PGADGPAGAPGTPGPQGIAGQRGVVG 962
Query: 354 SSNMRNSETSPGM 366
R PG+
Sbjct: 963 LPGQRGERGFPGL 975
Score = 68.6 bits (166), Expect = 1e-11
Identities = 85/307 (27%), Positives = 106/307 (34%), Gaps = 49/307 (15%)
Query: 59 AGGAAGSKVSEALGQGTREAVGT-------GVRQVPGFGAADALGNRVGEAAHALGNTGH 111
A G AG K EA QG G G PGF GEA G G
Sbjct: 606 AVGPAG-KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA----GKPGE 660
Query: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GN 164
+ D+ G RG +G PG G G G G+ G G G G
Sbjct: 661 Q--GVPGDLGAPGPSGARGE-RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717
Query: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224
PG G P + G PG G+ G+ P G G+ GP +GA PG VR
Sbjct: 718 PGSQGAPGLQGMPGER-GAAGLP---GPKGDRGDAGP-------KGADGSPGKDGVRGLT 766
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
G PP G G SG + G+ GD G + G
Sbjct: 767 ---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 285 SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GES 343
+ G G++G ++GD+G G + + G+ G G ARGS G
Sbjct: 824 GAKGEPGDAG-AKGDAGPPGPAGPAGPPGPIGNVGAPGAKG-----------ARGSAGPP 871
Query: 344 GIQGFRG 350
G GF G
Sbjct: 872 GATGFPG 878
Score = 67.8 bits (164), Expect = 2e-11
Identities = 63/248 (25%), Positives = 89/248 (35%), Gaps = 23/248 (9%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG +G G G G +GG G +G+ G PG +G P G G P
Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA 943
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
GAP G GP +G V PG R G + P G+S G G
Sbjct: 944 GAP----GTPGPQGIA-GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWG 307
+G G++ + G S G G +G +G G+ G G+ G
Sbjct: 999 PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058
Query: 308 SSTGSSSGNHGGSGGGNGHKP----------GCEKPGNEARGSGESGIQGFRGQGVSSNM 357
+ SG+ G +G P G + P + +GE G +G +G S +
Sbjct: 1059 PA--GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGL 1116
Query: 358 RNSETSPG 365
+ PG
Sbjct: 1117 QGPPGPPG 1124
Score = 66.2 bits (160), Expect = 5e-11
Identities = 87/313 (27%), Positives = 114/313 (36%), Gaps = 49/313 (15%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAE 118
A G AG++ ++ TG PGF A VG A G G + R +E
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA------VG----AKGEAGPQGPRGSE 364
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
G VRG G PG GA +G G G G G G PG G P G+PG
Sbjct: 365 -----GPQGVRGE-PGPPGPAGAAGPAGNPGADGQPGAKGANGA--PGIAGAP---GFPG 413
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ-GAVAQPGYGSV------------RASNQ 225
S P G P +G +G P G+ GA +PG V R +
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 226 NEGCTN--PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283
G T PP GG S G+ +G G + + GS + G +G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 284 --GSSG--GSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
G+ G GS G+ G G G +G + G + G G G K +PG
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593
Query: 335 NEARGSGESGIQG 347
+GE G+ G
Sbjct: 594 K----AGERGVPG 602
Score = 66.2 bits (160), Expect = 5e-11
Identities = 68/259 (26%), Positives = 85/259 (32%), Gaps = 40/259 (15%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG----QGNPGGLGTPWVHGYPGNSAGSFGMNP 188
+GVPG GA +G G G+QG G G +G G G+P G PG
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG---------- 647
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN---QNEGCTNPP----PSGSGGGS 241
P G G G P G + PG R G PP P G+ G
Sbjct: 648 ---PAGPPGEAGKPG-EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 242 SNSG--------GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
N G G GSQ G G+ G +G S G G
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVR 763
Query: 294 G-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGIQ 346
G G G +G+ G S S G+ G G + PG P A G G
Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 347 GFRGQGVSSNMRNSETSPG 365
G +G+ + + PG
Sbjct: 824 GAKGEPGDAGAKGDAGPPG 842
Score = 61.6 bits (148), Expect = 1e-09
Identities = 90/342 (26%), Positives = 125/342 (36%), Gaps = 53/342 (15%)
Query: 59 AGGAAGSKVSEALGQ-GTREAVGT-GVRQVPGF-GAADALGNR-VGEAAHALGNTGHEIG 114
A G AG+ ++ GQ G + A G G+ PGF GA G + G GN+G
Sbjct: 381 AAGPAGNPGAD--GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP-- 436
Query: 115 RQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWV 173
GA +G G G G G G G +G G +G+ P GL G P
Sbjct: 437 ---------GAPGSKGD-TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGE 486
Query: 174 HGYPGNSA--GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA--------- 222
G PG+ G+ G+ P G+ G+ GP + G +PG +
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPGPAG-PKGSPGEAGRPGEAGLPGAKGLTGSPG 545
Query: 223 SNQNEGCTNPP----------PSGSGGGSSNSG--GGSGSQSGSSGSGSNGDNNNGSSSG 270
S +G T PP P G G +G G G + + G G+ G
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
G + G +G +G G +G +GS G + G G G
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665
Query: 329 GCEKPG-NEARGS----GESGIQGFRGQGVSSNMRNSETSPG 365
PG + ARG GE G+QG G + R + +PG
Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPG---PAGPRGANGAPG 704
Score = 61.6 bits (148), Expect = 1e-09
Identities = 64/230 (27%), Positives = 79/230 (34%), Gaps = 26/230 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG--A 191
G PG GA ++G G G G G G P G P G PG + G P+G
Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP--PGPPGPAGKEGGKGPRGETG 914
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG--GSG 249
P G+ G GPP PG + S +G P + G + G G
Sbjct: 915 PAGRPGEVGPP----------GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964
Query: 250 SQSGSSG----SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDS 300
Q G G G +G+ SG S G G G SG G+ G
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G + S G+ G G G PG P A SG+ G G G
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPGAPG-APGAPGPVGPAGKSGDRGETGPAG 1073
Score = 59.3 bits (142), Expect = 6e-09
Identities = 68/250 (27%), Positives = 88/250 (35%), Gaps = 40/250 (16%)
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGN 179
+ +G D VPG G SG G+ G G G QG QG PG PG
Sbjct: 163 LSYGYDEKSTGGISVPGPMGP---SGPRGLPGPPGAPGPQGFQGPPGE---------PGE 210
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG 239
S M P+G P G NG G +PG R P P G+ G
Sbjct: 211 PGASGPMGPRGPPGPPGKNG--------DDGEAGKPGRPGERGP--------PGPQGARG 254
Query: 240 --GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--G 295
G++ G G + S G+ GD G S +G G G G G
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG 314
Query: 296 SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSS 355
+ G +G+ + G++ + G G G PG GE+G QG RG
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGF-PGA------VGAKGEAGPQGPRGSEGPQ 367
Query: 356 NMRNSETSPG 365
+R PG
Sbjct: 368 GVRGEPGPPG 377
Score = 59.3 bits (142), Expect = 6e-09
Identities = 61/226 (26%), Positives = 78/226 (34%), Gaps = 24/226 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G G G G G QG G G+ G PG +G P + G PG S +G+P
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024
Query: 193 W-----------GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G+ G GPP GA PG + + G T P G
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPG----APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSG 301
+ G +G Q G G+ + G G S G G SG S G +G
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS-GPAG 1139
Query: 302 SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQG 347
GS+ G G NG PG R +G++G G
Sbjct: 1140 PRGPPGSAGAP------GKDGLNGLPGPIGPPGPRGR-TGDAGPVG 1178
Score = 38.5 bits (88), Expect = 0.011
Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G G G G+ G PG +G P G G+ AG G P
Sbjct: 1124 GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD-AGPVG--PP 1180
Query: 190 GAPWGQGGNGGPPNFG 205
G P G G GPP+ G
Sbjct: 1181 GPP-GPPGPPGPPSAG 1195
Score = 35.8 bits (81), Expect = 0.070
Identities = 29/85 (34%), Positives = 32/85 (37%), Gaps = 9/85 (10%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+ GH G G G GS G G G P G G P G PG G+N
Sbjct: 1105 RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD----GLNGLPG 1160
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPG 216
P G G P T G V PG
Sbjct: 1161 PIGPPG----PRGRTGDAGPVGPPG 1181
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 79.7 bits (195), Expect = 4e-15
Identities = 101/350 (28%), Positives = 128/350 (36%), Gaps = 31/350 (8%)
Query: 19 GEAGPL-QSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G GP+ +G +G A G GL G + SEG G AG K S +G R
Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG--------PVGPAGKKGS----RGER 1045
Query: 77 EAVG-TGVRQVPG----FGAADALGNRVGEAAHA-LGNTGHEIGRQAE-DVIRHGADAVR 129
G TG +PG G A G E +G GH+ + + D G +R
Sbjct: 1046 GPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIR 1105
Query: 130 G--SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGS 183
G G PG +GA G G+FG +G G +G G PG G P G G
Sbjct: 1106 GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165
Query: 184 FGMNPQGAPWGQGGNGGPPNFGT-NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
M P GAP +G G + GT G V QPG + + G PP + G
Sbjct: 1166 GSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
G G S +G G G S +G G G SG GS G+
Sbjct: 1226 GDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G G + G+ G G + G E R GE G +G G
Sbjct: 1286 GDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGR-EGEKGAKGEPG 1334
Score = 68.6 bits (166), Expect = 1e-11
Identities = 71/245 (28%), Positives = 82/245 (33%), Gaps = 35/245 (14%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGN--------SAGSF 184
G PG G G G G QG G QG P GL GTP G PGN S G
Sbjct: 623 GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPL 682
Query: 185 GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNS 244
G P G+ G GPP G+ PGY P P G G S N
Sbjct: 683 GHPGHEGPTGEKGAQGPP-------GSAGPPGY--------------PGPRGVKGTSGNR 721
Query: 245 G--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
G G G + G GD G + G G +G +G G G +
Sbjct: 722 GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSA 781
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
G + G G G G PG P E SG++G G G+ R
Sbjct: 782 GEKGKLGVPGLPGYPGRPGPKGSIGF-PGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGE 840
Query: 361 ETSPG 365
PG
Sbjct: 841 RGQPG 845
Score = 62.8 bits (151), Expect = 5e-10
Identities = 78/305 (25%), Positives = 102/305 (33%), Gaps = 28/305 (9%)
Query: 66 KVSEALGQGTREAVG-TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
K+ G R G TG + GF L G+ G+ GH +G+ G
Sbjct: 528 KMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQR----GDFGH-VGQPGPP----G 578
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184
D RG+ +G PG G G G+ G +G +PG G P V G G
Sbjct: 579 EDGERGA-EGPPGPTGQAGEPGPRGLLGPRG--------SPGPTGRPGVTGIDGAPGAKG 629
Query: 185 GMNPQGAPW--GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
+ P G P GQ GN G QG + PG + N G P S G
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGL-PGPQGLIGTPG---EKGPPGNPGIPGLPGSDGPLGHP 685
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
G +G + GS G G + + G G G G +GD G
Sbjct: 686 GHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDG-FPGFKGDVGL 744
Query: 303 ESSWGSSTGSSSGNHGGSGG--GNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
+ G G G G + G E P A G+ G+ G G + S
Sbjct: 745 KGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS 804
Query: 361 ETSPG 365
PG
Sbjct: 805 IGFPG 809
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/257 (28%), Positives = 88/257 (34%), Gaps = 36/257 (14%)
Query: 123 HGADAVRGSWQ--GVPGHNGAWETSGGHGIFGSQGGLGGQG----------QGNPGGLGT 170
HG+ + G G PG G G G+ GS G LG G QG PG G
Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705
Query: 171 PWVHGYPGNSA--GSFGMNPQGAPWGQGGNGGPPNF--GTNTQGAVAQPGYGSVRASNQN 226
P GYPG G+ G G+ G G P F +G +PG R +
Sbjct: 706 P---GYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762
Query: 227 EGCTNPPPSGSGGGSSNSG-GGSGSQSGSSG-------SGSNGDNNNGSSSGGSSSGSSS 278
EG P G G + G GS + G G G G + G
Sbjct: 763 EG-----PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEK 817
Query: 279 GGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPG 334
G S G G G GSRG+ G + G G+ G G K PG + P
Sbjct: 818 GKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 335 NEARGSGESGIQGFRGQ 351
G G QG G+
Sbjct: 878 GFPGPKGPPGHQGKDGR 894
Score = 58.9 bits (141), Expect = 8e-09
Identities = 71/255 (27%), Positives = 89/255 (34%), Gaps = 26/255 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G+PGH G G G G QG G QG G PG +G G PG + G+ G+ P
Sbjct: 494 GLPGHPG---LKGEEGAEGPQGPRGLQGPHGPPGRVGK---MGRPG-ADGARGLPGDTGP 546
Query: 193 WGQGGNGGPPNF-GTNTQ----GAVAQPGYGSVRASNQNEGCTNPPPSGSGG-------- 239
G G G P G Q G V QPG EG P P+G G
Sbjct: 547 KGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEG--PPGPTGQAGEPGPRGLL 604
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSR 297
G S G +G + G+ G N G G G G G G +
Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664
Query: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM 357
G G+ G H G G G K G + P A G G +G +G + +
Sbjct: 665 GPPGNPGIPGLPGSDGPLGHPGHEGPTGEK-GAQGPPGSAGPPGYPGPRGVKGTSGNRGL 723
Query: 358 RNSETSPGMFNFDTF 372
+ + G F F
Sbjct: 724 QGEKGEKGEDGFPGF 738
Score = 58.9 bits (141), Expect = 8e-09
Identities = 81/307 (26%), Positives = 103/307 (33%), Gaps = 35/307 (11%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G AG E E GV +PG+ +G LG G E G+ +
Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPG-PLGPIG-EKGKSGKT- 823
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGN 179
G + G +G PG G G G G +G +G G G PG G P + G PG
Sbjct: 824 ---GQPGLEGE-RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFG----TNTQGAVAQPGYGSVRASNQNEGCTNP--- 232
P+G P QG +G P + G QG PG V G P
Sbjct: 880 PG------PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933
Query: 233 --PPSGSGGGSSNSGGGSGSQSGSSGS-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
PP G G + G+ G G G +G GG G
Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993
Query: 290 SGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG----S 340
G+ G G+ G G G + G GS G G P +K RG +
Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG--PAGKKGSRGERGPPGPT 1051
Query: 341 GESGIQG 347
G+ GI G
Sbjct: 1052 GKDGIPG 1058
Score = 55.5 bits (132), Expect = 9e-08
Identities = 78/277 (28%), Positives = 98/277 (35%), Gaps = 35/277 (12%)
Query: 131 SWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
S +G PG G G G+ G G G +G +G G G HG PG +
Sbjct: 476 SMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR------VGKM 529
Query: 190 GAPWGQGGNGGP----PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
G P G G P P G PG R + G PP G+
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589
Query: 246 GGSGSQSGSSG-------SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G +G Q+G G GS G +G + + G G G G GS
Sbjct: 590 GPTG-QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648
Query: 297 RGDSGSESSWGS-STGSSSGNHG-----GSGGGNGHKPGCEKPGNE--ARG----SGESG 344
+G G + G+ GN G GS G GH PG E P E A+G +G G
Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGH-PGHEGPTGEKGAQGPPGSAGPPG 707
Query: 345 IQGFRGQGVSSNMRNSETSPGMFNFDTFWKNFKSKLG 381
G RG +S R + G D F FK +G
Sbjct: 708 YPGPRGVKGTSGNRGLQGEKGEKGEDGF-PGFKGDVG 743
Score = 52.4 bits (124), Expect = 7e-07
Identities = 49/163 (30%), Positives = 66/163 (40%), Gaps = 15/163 (9%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNS 180
R G + +G+ +G PG +G +G G G G +G +G +G PG +G P + G PG
Sbjct: 1320 REGREGEKGA-KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQM 1378
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFG-TNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSG 238
+ P G P +G G G G + PG + G PP P G
Sbjct: 1379 GPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDP 1438
Query: 239 G-----GSSNSGGGSG-----SQSGSSGS-GSNGDNNNGSSSG 270
G GS G G Q GS GS GS G + +G
Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAG 1481
Score = 47.0 bits (110), Expect = 3e-05
Identities = 67/250 (26%), Positives = 75/250 (30%), Gaps = 38/250 (15%)
Query: 124 GADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYP 177
G D +GS G+PG G G GI GS G G G G PG G P G P
Sbjct: 1250 GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPP 1309
Query: 178 GNSAGSFGMNPQG-----------APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQN 226
G S M +G P G G GP G V G +
Sbjct: 1310 GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG-ARGPPGRVGPEGLRGI------ 1362
Query: 227 EGCTNPPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
P P G G G+ G G S G GD G G
Sbjct: 1363 -----PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA 1417
Query: 285 SSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEA 337
G G G G +GD G GS G G G K PG P +
Sbjct: 1418 GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDT 1477
Query: 338 RGSGESGIQG 347
+G G G
Sbjct: 1478 GPAGPPGPPG 1487
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/225 (27%), Positives = 74/225 (32%), Gaps = 12/225 (5%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQG 190
++G PG G G G G G G G P GL G P + G G M Q
Sbjct: 390 FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQF 449
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-NPPPSGSGG--GSSNSGGG 247
A G G P +F AV Q S++ G T P P G G G G
Sbjct: 450 A--GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGA 507
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESS 305
G Q G +G G + + G G G G G G+ G
Sbjct: 508 EGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+G G G G PG P +A G G+ G RG
Sbjct: 568 FGHVGQPGPPGEDGERGAEG-PPG---PTGQAGEPGPRGLLGPRG 608
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/202 (26%), Positives = 67/202 (33%), Gaps = 28/202 (13%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G +G G +G+ G PG G G PG G G+
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGR-VGPEGLRGI 1362
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG---------- 239
P G+ G G P G + PG +G T P G G
Sbjct: 1363 PGPVGEPGLLGAP-------GQMGPPGPLGPSGLPGLKGDTG--PKGEKGHIGLIGLIGP 1413
Query: 240 -GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G + G G G GD G G + GS G+ G G
Sbjct: 1414 PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473
Query: 297 RGDSGSESSWGSSTGSSSGNHG 318
RGD+G G G+ + HG
Sbjct: 1474 RGDTGPAGPPG-PPGAPAELHG 1494
Score = 32.7 bits (73), Expect = 0.59
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 6/78 (7%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
QG+PG G G G G G +G G P G+ P G G+ M P+G
Sbjct: 1423 QGLPGVQGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPL--GQKGSKGSPGSMGPRG-D 1476
Query: 193 WGQGGNGGPPNFGTNTQG 210
G G GPP G
Sbjct: 1477 TGPAGPPGPPGAPAELHG 1494
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
Query: 318 GG--SGGGNGHKPGCEKPGNEARG 339
GG SGGG G G G+ RG
Sbjct: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
Score = 73.9 bits (180), Expect = 2e-13
Identities = 53/156 (33%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
SNG ++ SSGG+ GS GG S+G SG + SR G+ GS G G
Sbjct: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
Query: 317 HGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
GSGGG G G G + G G+ G G
Sbjct: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG 602
Score = 67.0 bits (162), Expect = 3e-11
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
Query: 321 GGGNG 325
G G G
Sbjct: 595 GSGKG 599
Score = 65.9 bits (159), Expect = 6e-11
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
Score = 64.7 bits (156), Expect = 1e-10
Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 13/142 (9%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGD----NNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
SG GS N G Q GS GD NN GS +G S G G SS S GN
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
Query: 293 --SGGSRGDSGSESSWGSSTGSS------SGNHGGSGGGNGHKPGCEKPGNEARGSGES- 343
SG +G G + S G +G + G GG G G G +PG +G G+
Sbjct: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGH 580
Query: 344 GIQGFRGQGVSSNMRNSETSPG 365
G G + G + + S G
Sbjct: 581 GSGGGKNSGGGKGSGSGKGSDG 602
Score = 60.1 bits (144), Expect = 3e-09
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 41/210 (19%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS---- 516
Query: 117 AEDVIRHGADAVRGSWQGVPGHNGA--------------WETSGGHGIFGSQGGLGGQGQ 162
G + G QG G G+ T+GGHG G Q GG G
Sbjct: 517 ------SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
Query: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA 222
G GG G PG+ GS G G G G G G + + +G +
Sbjct: 571 G--GGQG-------PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQ 621
Query: 223 SNQNE------GCTNPPPSGSGGGSSNSGG 246
S Q + PPP+G GG SGG
Sbjct: 622 SKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 77.0 bits (188), Expect = 3e-14
Identities = 77/259 (29%), Positives = 95/259 (36%), Gaps = 30/259 (11%)
Query: 124 GADAVRGSW-----QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYP 177
GAD + G+ QG PG G G G+ G G G +G+ G PG G P G P
Sbjct: 651 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 710
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP--PPS 235
G P G G +G P G + GA+ PG + + + G T P P
Sbjct: 711 GLPGPEGARGPPGFKGHTGDSGAPGPRGES--GAMGLPGQEGLPGKDGDTGPTGPQGPQG 768
Query: 236 GSGGGSSNSGGGSGSQSGSSGS----GSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG 287
G N GS + G SG+ GS G+N + G G G G G G
Sbjct: 769 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 828
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--------PGCEKPGN 335
G G G G RGD G + G G G G GH PG P
Sbjct: 829 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 888
Query: 336 EARGSGESGIQGFRGQGVS 354
G+ G G RG+ S
Sbjct: 889 PPGPPGQPGFPGLRGESPS 907
Score = 70.5 bits (171), Expect = 3e-12
Identities = 67/245 (27%), Positives = 85/245 (34%), Gaps = 21/245 (8%)
Query: 122 RHGADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHG 175
R G + +G G+PG G G G G+ G +G +G G PG +G P G
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 648
Query: 176 YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS 235
PG + P G G G GPP QG PG +G PP
Sbjct: 649 PPGADGIAGAAGPPGIQ-GSPGKEGPPG----PQGPSGLPGIPGEEGKEGRDGKPGPPGE 703
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG- 294
G G G++ G GD+ G S + G G +G +G
Sbjct: 704 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 763
Query: 295 -------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGI 345
G G +GS S G S + GS G NG PG P GE G+
Sbjct: 764 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 823
Query: 346 QGFRG 350
G G
Sbjct: 824 PGKEG 828
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/245 (28%), Positives = 90/245 (36%), Gaps = 28/245 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G PG G H + G G+ +G+PG G P + G PG P GA
Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGE-KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 386
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGY-GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
+G +G P GA PG G V A G + PP S G + G G +
Sbjct: 387 QEGAHGAP--------GAAGNPGAPGHVGA----PGPSGPPGSVGAPGLRGTPGKDGERG 434
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG-----GSSGNSG--GSRGDSGSESS 305
+G G G + G G G GS G G G++GD G+
Sbjct: 435 EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGI 494
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG-QG-VSSNMRNSETS 363
G S G+ G G G PG P + G G+ GF G QG + +S S
Sbjct: 495 PG-----SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLS 549
Query: 364 PGMFN 368
PG N
Sbjct: 550 PGDIN 554
Score = 56.6 bits (135), Expect = 4e-08
Identities = 77/294 (26%), Positives = 98/294 (33%), Gaps = 57/294 (19%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-- 179
+ G +RGS PG G T G G G G G +G G G P G PG+
Sbjct: 467 KDGEPGLRGS----PGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522
Query: 180 SAGSFGM----NPQGAPWGQGGNG---------------------GPPNFG--TNTQGAV 212
S GS G+ PQG P G+ G GPP +G
Sbjct: 523 SPGSRGLPGFPGPQG-PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGS 272
PG + +G PP G + G G + G GD + G
Sbjct: 582 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641
Query: 273 SSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSS----TGSSSGNHGGSG----- 321
+ G G++G G GS G G G S G G G
Sbjct: 642 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 701
Query: 322 --GGNGHKPGCEKPGNE-ARG-------SGESGIQGFRGQGVSSNMRNSETSPG 365
G +PG PG E ARG +G+SG G RG+ + + E PG
Sbjct: 702 GEPGKAGEPGL--PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 753
Score = 48.9 bits (115), Expect = 8e-06
Identities = 85/338 (25%), Positives = 108/338 (31%), Gaps = 58/338 (17%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G + PG L R GE G TG + E HGA G+ G PGH GA
Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQ-GPTGPPGAKGQEGA--HGAPGAAGN-PGAPGHVGA 408
Query: 142 WETSGGHGIFGSQGGLGGQG-------------QGNPGGLG------TPWVHGYPGNSA- 181
SG G G+ G G G +G+PG +G P + G PG
Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 468
Query: 182 ------GSFGM----------NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
GS G+ G P G G P G PG S
Sbjct: 469 GEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG 528
Query: 226 NEGCTNPP-PSGSGGGSSNSGGG----------SGSQSGSSG----SGSNGDNNNGSSSG 270
G P P+G G SS G + G G G GD G
Sbjct: 529 LPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 588
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
+ G + G G +G GS+G+ G++ G G G G+ P
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN-P 647
Query: 329 GCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGM 366
G A +G GIQG G+ + PG+
Sbjct: 648 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI 685
Score = 45.4 bits (106), Expect = 9e-05
Identities = 81/333 (24%), Positives = 107/333 (32%), Gaps = 72/333 (21%)
Query: 82 GVRQVPGF----GAADALGNRVGEAAHALGNTGHE-IGRQAEDVIRHGADAVRGSWQGVP 136
G R PGF G + A G R GE+ A+G G E + + D G +G +G P
Sbjct: 717 GARGPPGFKGHTGDSGAPGPR-GESG-AMGLPGQEGLPGKDGDTGPTGPQGPQGP-RGPP 773
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQ----------------GNPGGLGTPWVHGYPGNS 180
G NG+ + G G G+ G G +G+ G PG G P G PG
Sbjct: 774 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG-K 832
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY-------GSVRASNQNEGCTNPP 233
G G + G G+ GPP G G PG+ G +N P
Sbjct: 833 PGEPGFKGERGDPGIKGDKGPPG-GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 891
Query: 234 PSGSGGGSSNSGGGSGSQS----------------------------GSSGSGSNGDNNN 265
P G G G ++ S G G
Sbjct: 892 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 951
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHG----- 318
G G GG G SG G +G+ G++ G+ G G
Sbjct: 952 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1011
Query: 319 GSGGGNGHK----PGCEKPGNEARGSGESGIQG 347
G G G+ PG P E +G G+ G
Sbjct: 1012 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG 1044
Score = 33.9 bits (76), Expect = 0.27
Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGG---HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGM 186
G PG G SG G G++G G G G G +G P + G PG G G+
Sbjct: 968 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1027
Query: 187 -NPQG--APWGQGGNGGPP 202
PQG P G G GPP
Sbjct: 1028 PGPQGETGPAGHPGLPGPP 1046
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 77.0 bits (188), Expect = 3e-14
Identities = 77/259 (29%), Positives = 95/259 (36%), Gaps = 30/259 (11%)
Query: 124 GADAVRGSW-----QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYP 177
GAD + G+ QG PG G G G+ G G G +G+ G PG G P G P
Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP--PPS 235
G P G G +G P G + GA+ PG + + + G T P P
Sbjct: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGES--GAMGLPGQEGLPGKDGDTGPTGPQGPQG 1321
Query: 236 GSGGGSSNSGGGSGSQSGSSGS----GSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG 287
G N GS + G SG+ GS G+N + G G G G G G
Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--------PGCEKPGN 335
G G G G RGD G + G G G G GH PG P
Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
Query: 336 EARGSGESGIQGFRGQGVS 354
G+ G G RG+ S
Sbjct: 1442 PPGPPGQPGFPGLRGESPS 1460
Score = 60.1 bits (144), Expect = 3e-09
Identities = 85/328 (25%), Positives = 104/328 (31%), Gaps = 68/328 (20%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGH----------------EIGRQAEDVIRHGA 125
G R +PGF R G A GN G +I A+DV
Sbjct: 1063 GSRGLPGFPGPQGPAGRDG----APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCN--- 1115
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSF 184
D G G+PG G G G G +G G +G+ P GL G P + G P S G
Sbjct: 1116 DCPPGP-PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG-PQGSQGER 1173
Query: 185 G-------------------MNPQGAPWGQGGNG-----GPPNF--------GTNTQGAV 212
G M P G P G +G GPP QG
Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGS 272
PG +G PP G G G++ G GD+ G S
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
Query: 273 SSGSSSGGSSGGSSGGSSGNSG--------GSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
+ G G +G +G G G +GS S G S + GS G N
Sbjct: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353
Query: 325 GHK--PGCEKPGNEARGSGESGIQGFRG 350
G PG P GE G+ G G
Sbjct: 1354 GSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/385 (25%), Positives = 127/385 (32%), Gaps = 68/385 (17%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
GE G +GEE + +G GD + G+ GK G G + S L
Sbjct: 952 GEKGA--AGEEGSPGPVGPR-----GDPGAPGLPGPPGKGKDGEPGLRGSPGL------- 997
Query: 79 VGTGVRQVPG-FGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS----WQ 133
PG G A G G ALG + R A + G+ RG
Sbjct: 998 --------PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI--PGSPGSRGDPGIGVA 1047
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNP---- 188
G PG +G G G G G G QG G G G P G PG S ++P
Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107
Query: 189 -------QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
P G G G P F +G PG + +G PP G
Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGF----KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGI 1163
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGD 299
+ G G + G GD + G + G G++G G GS G
Sbjct: 1164 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 1223
Query: 300 SGSESSWGSS----TGSSSGNHGGSGG-------GNGHKPGCEKPGNE-ARG-------S 340
G G S G G G G +PG PG E ARG +
Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL--PGPEGARGPPGFKGHT 1281
Query: 341 GESGIQGFRGQGVSSNMRNSETSPG 365
G+SG G RG+ + + E PG
Sbjct: 1282 GDSGAPGPRGESGAMGLPGQEGLPG 1306
Score = 57.8 bits (138), Expect = 2e-08
Identities = 63/249 (25%), Positives = 84/249 (33%), Gaps = 24/249 (9%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G PG G H + G G+ +G+PG G P + G PG P GA
Sbjct: 846 GPPGLPGTTSLFTPHPRMPGEQGPKGE-KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 904
Query: 194 GQGGNGGPPNFGT-NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
+G +G P G G V PG S G P G + G GS
Sbjct: 905 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
Query: 253 --------------GSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSGGSSGGSSGNSGGS 296
G G G +G+ S G G ++ G GS + G
Sbjct: 965 PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ-CV 1023
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
+GD G+ G S G+ G G G PG P + G G+ GF G +
Sbjct: 1024 KGDRGAPGIPG-----SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG 1078
Query: 357 MRNSETSPG 365
+ +PG
Sbjct: 1079 RDGAPGNPG 1087
Score = 53.1 bits (126), Expect = 4e-07
Identities = 91/377 (24%), Positives = 111/377 (29%), Gaps = 42/377 (11%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G AGP+ G +IG G E IG G G K S L
Sbjct: 487 GVAGPM--GLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRD 544
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHA-----------LGNTGHEIGRQAEDVIRHGADA 127
G+R PG L VG +G G + G + E R G
Sbjct: 545 GSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQ-GERGEKGTR-GEKG 602
Query: 128 VRG--SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL--------GTPWVHGYP 177
RG + G PG G G G+ G QG G G P G+ G G P
Sbjct: 603 ERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAP 662
Query: 178 GNSAGSFGMNPQGA--PWGQGGNGGPPNF-----GTNTQGAVAQPGYGSVRASNQNEGCT 230
G P GA P G G GPP G PG ++ G
Sbjct: 663 GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVP 722
Query: 231 NPPPSGSGGGSSNSGGGSGSQSGSSGSGSNG-DNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
PP G G G G +G G D NG + G G G
Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG-- 780
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFR 349
G RG+ G + G G+ G PG + GE G+ G +
Sbjct: 781 ---KPGLRGEIGEQGLAGRPGEKGEAGLPGAPG----FPGVRGEKGDQGEKGELGLPGLK 833
Query: 350 GQGVSSNMRNSETSPGM 366
G PG+
Sbjct: 834 GDRGEKGEAGPAGPPGL 850
Score = 52.4 bits (124), Expect = 7e-07
Identities = 72/279 (25%), Positives = 87/279 (31%), Gaps = 48/279 (17%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGM------ 186
G PG G G G G G LG QG G PG G P G PG G G
Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG-LPGEIGFPGKPGP 745
Query: 187 -NPQGAPWGQGGNGGPPNFGT----NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
P G P G NG P GT +G PG +R +G P G
Sbjct: 746 PGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGL 805
Query: 242 SNSGG--GSGSQSGSSGS-------GSNGDNNNGSSSGGSSSGSSSGGSS--------GG 284
+ G G + G G G GD +G + G +S G
Sbjct: 806 PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 865
Query: 285 SSG--GSSGNSG--------------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH-- 326
G G G+ G G +G +G + G + G+ G GH
Sbjct: 866 EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 925
Query: 327 KPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
PG P G G G G+ E SPG
Sbjct: 926 APGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
Score = 46.2 bits (108), Expect = 5e-05
Identities = 77/284 (27%), Positives = 91/284 (32%), Gaps = 43/284 (15%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPG--GL-GTPWVHGYPGNS 180
G D RG +G G G+ G G G+ G G G+G G GL G+P + G G
Sbjct: 946 GKDGERGE-KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004
Query: 181 A--------------GSFGMNPQGAPW--GQGGNGGPPNFG-TNTQGAVAQPGYGSVRAS 223
A G +GAP G G+ G P G G PG S
Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 1064
Query: 224 NQNEGCTNPP-PSGSGGGSSNSG-GGSGSQSGSSGSGSNGDNN-------NGSSSGGSSS 274
G P P+G G N G G + G S S GD N N G
Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL 1124
Query: 275 GSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWG----SSTGSSSGNHGGSG-----GG 323
G G G G G +G++G G + S G G G G
Sbjct: 1125 PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGD 1184
Query: 324 NGHK--PGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
GH PG P G GI G G E PG
Sbjct: 1185 QGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
Score = 45.8 bits (107), Expect = 7e-05
Identities = 53/218 (24%), Positives = 70/218 (32%), Gaps = 30/218 (13%)
Query: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW--GQGGNGGPPNFGTNTQGAVAQPGYGSV 220
G G +G G PG + P GAP G+ G+ G FG +G G
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540
Query: 221 RASNQNEGCTNPP----------------PSGSGG--GSSNSGGGSGSQSGSSGSGSNGD 262
+ ++G P P G G G G G Q G+ G+
Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600
Query: 263 NNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG--SSTGSSSGNHG-- 318
G +G G +G G +GD G G S G G
Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQ-GEKGDVGPAGPPGVPGSVVQQEGLKGEQ 659
Query: 319 GSGGGNGHK-----PGCEKPGNEARGSGESGIQGFRGQ 351
G+ G GH+ PG P G G+QG RG+
Sbjct: 660 GAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGK 697
Score = 45.4 bits (106), Expect = 9e-05
Identities = 81/333 (24%), Positives = 107/333 (32%), Gaps = 72/333 (21%)
Query: 82 GVRQVPGF----GAADALGNRVGEAAHALGNTGHE-IGRQAEDVIRHGADAVRGSWQGVP 136
G R PGF G + A G R GE+ A+G G E + + D G +G +G P
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPR-GESG-AMGLPGQEGLPGKDGDTGPTGPQGPQGP-RGPP 1326
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQ----------------GNPGGLGTPWVHGYPGNS 180
G NG+ + G G G+ G G +G+ G PG G P G PG
Sbjct: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG-K 1385
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY-------GSVRASNQNEGCTNPP 233
G G + G G+ GPP G G PG+ G +N P
Sbjct: 1386 PGEPGFKGERGDPGIKGDKGPPG-GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
Query: 234 PSGSGGGSSNSGGGSGSQS----------------------------GSSGSGSNGDNNN 265
P G G G ++ S G G
Sbjct: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 1504
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHG----- 318
G G GG G SG G +G+ G++ G+ G G
Sbjct: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1564
Query: 319 GSGGGNGHK----PGCEKPGNEARGSGESGIQG 347
G G G+ PG P E +G G+ G
Sbjct: 1565 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG 1597
Score = 33.9 bits (76), Expect = 0.27
Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGG---HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGM 186
G PG G SG G G++G G G G G +G P + G PG G G+
Sbjct: 1521 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1580
Query: 187 -NPQG--APWGQGGNGGPP 202
PQG P G G GPP
Sbjct: 1581 PGPQGETGPAGHPGLPGPP 1599
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 77.0 bits (188), Expect = 3e-14
Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 43/321 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMRNSETSP 364
GQ G + + TSP
Sbjct: 348 AGQNQHPSGATPTLNQLLTSP 368
Score = 56.2 bits (134), Expect = 5e-08
Identities = 74/286 (25%), Positives = 101/286 (35%), Gaps = 37/286 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSGES--GIQGFRGQGVSSNM 357
GGS + P +P ++A +G + G Q G G+ +M
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM 421
Score = 53.1 bits (126), Expect = 4e-07
Identities = 59/239 (24%), Positives = 80/239 (33%), Gaps = 31/239 (12%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW-GQGGN--GGPPNFGTNTQ 209
S GG GG G PG HG +SA +P G P + G+ PP G
Sbjct: 81 SLGGAGG-GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG 139
Query: 210 GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--------SNSGGGSGSQSGSSG--SGS 259
G PG G++ G PP + GGG +N G + SG G +G
Sbjct: 140 GRYEHPGLGAL-------GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGP 192
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE----------SSWGSS 309
D + G S G S+ ++ G+ G G S+ + G
Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252
Query: 310 TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFN 368
G G G GGG G G G A + + G G S G+ +
Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLS 311
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 77.0 bits (188), Expect = 3e-14
Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 43/321 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMRNSETSP 364
GQ G + + TSP
Sbjct: 348 AGQNQHPSGATPTLNQLLTSP 368
Score = 56.2 bits (134), Expect = 5e-08
Identities = 74/286 (25%), Positives = 101/286 (35%), Gaps = 37/286 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSGES--GIQGFRGQGVSSNM 357
GGS + P +P ++A +G + G Q G G+ +M
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM 421
Score = 53.1 bits (126), Expect = 4e-07
Identities = 59/239 (24%), Positives = 80/239 (33%), Gaps = 31/239 (12%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW-GQGGN--GGPPNFGTNTQ 209
S GG GG G PG HG +SA +P G P + G+ PP G
Sbjct: 81 SLGGAGG-GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG 139
Query: 210 GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--------SNSGGGSGSQSGSSG--SGS 259
G PG G++ G PP + GGG +N G + SG G +G
Sbjct: 140 GRYEHPGLGAL-------GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGP 192
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE----------SSWGSS 309
D + G S G S+ ++ G+ G G S+ + G
Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252
Query: 310 TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFN 368
G G G GGG G G G A + + G G S G+ +
Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLS 311
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 77.0 bits (188), Expect = 3e-14
Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 43/321 (13%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
SS G S G G GGG G A GS G Q F
Sbjct: 303 SSAGYG----------VLSSPRQQGGGMMMGPGGG-----GAASLSKAAAGSAAGGFQRF 347
Query: 349 RGQ-----GVSSNMRNSETSP 364
GQ G + + TSP
Sbjct: 348 AGQNQHPSGATPTLNQLLTSP 368
Score = 56.2 bits (134), Expect = 5e-08
Identities = 74/286 (25%), Positives = 101/286 (35%), Gaps = 37/286 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSGES--GIQGFRGQGVSSNM 357
GGS + P +P ++A +G + G Q G G+ +M
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDM 421
Score = 53.1 bits (126), Expect = 4e-07
Identities = 59/239 (24%), Positives = 80/239 (33%), Gaps = 31/239 (12%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW-GQGGN--GGPPNFGTNTQ 209
S GG GG G PG HG +SA +P G P + G+ PP G
Sbjct: 81 SLGGAGG-GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG 139
Query: 210 GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--------SNSGGGSGSQSGSSG--SGS 259
G PG G++ G PP + GGG +N G + SG G +G
Sbjct: 140 GRYEHPGLGAL-------GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGP 192
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE----------SSWGSS 309
D + G S G S+ ++ G+ G G S+ + G
Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252
Query: 310 TGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFN 368
G G G GGG G G G A + + G G S G+ +
Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLS 311
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 75.5 bits (184), Expect = 8e-14
Identities = 75/274 (27%), Positives = 102/274 (37%), Gaps = 27/274 (9%)
Query: 107 GNTGHEIGRQAEDVIRHGADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGN 164
GN G + Q +V +G D + G G+PG G G G G +G G +G
Sbjct: 1449 GNRG--LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGA-- 1504
Query: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224
G G P G + G G+ + G+ G GPP T G+ + R
Sbjct: 1505 KGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPG----TPGSRRKTAAHGRRGHT 1560
Query: 225 QNEGCTN-PPPSGSGG--------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
+G P P G G G G G + G G G G +G
Sbjct: 1561 GPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL 1620
Query: 276 SSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSG--GGNGHKPGCE 331
S G G G G G RG G++ S G + G G G G +G K
Sbjct: 1621 GSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIG 1680
Query: 332 KPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
PG G GE+G++G RG+ +S+ + SPG
Sbjct: 1681 DPG----GPGETGLKGARGKMISAGLPGEMGSPG 1710
Score = 57.8 bits (138), Expect = 2e-08
Identities = 91/351 (25%), Positives = 122/351 (34%), Gaps = 72/351 (20%)
Query: 19 GEAGPLQSGEEST-------GTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEAL 71
G GP+ GE+ T G L G+ G+ G++ + E
Sbjct: 1428 GAPGPV--GEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKG 1485
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEA---AHALGNTG--HEIGRQAEDVIRHGAD 126
+G++ + G R PG A L G + G TG E GRQ
Sbjct: 1486 DEGSQGSPGK--RGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQG--------- 1534
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186
R W G PG G+ + HG G G G G P GL GS G+
Sbjct: 1535 --RRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGL------------EGSLGL 1580
Query: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG- 245
P G+ G G G ++G PG G A NQ G G N G
Sbjct: 1581 KGPQGPRGEAGVKGEKG-GVGSKGPQGPPGPGG-EAGNQ----------GRLGSQGNKGE 1628
Query: 246 -GGSGSQSGSSGSGSNG-DNNNGSSSGGSSSGSSSGGSSG--GSSG--GSSGNSGGSRGD 299
G G + G G N+GS GS + G G G SG G G+ GG G+
Sbjct: 1629 PGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGP-GE 1687
Query: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+G + + G + GS G +PG G G++G +G
Sbjct: 1688 TGLKGARGKMISAGLPGEMGSPG----EPG---------PPGRKGVKGAKG 1725
Score = 45.8 bits (107), Expect = 7e-05
Identities = 65/250 (26%), Positives = 82/250 (32%), Gaps = 45/250 (18%)
Query: 161 GQGNPGGLGTPWVHGYPG--NSAGSFG----MNPQGAPWGQGGNGGPPNFGT-------N 207
G G G G P G PG S G G +GAP G G +GT
Sbjct: 1393 GDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRG 1452
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267
G + G + N +G P G S G G + G+ G +
Sbjct: 1453 LNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPG 1512
Query: 268 SSGGSSSGSSSGGSSG--GSSG-----GSSGNSG--------GSRGDSGSESSWG----- 307
+ G SS G G G G G G G G RG +G + + G
Sbjct: 1513 APGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPD 1572
Query: 308 ---SSTG--SSSGNHGGSG-----GGNGHK--PGCEKPGNEARGSGESGIQGFRGQGVSS 355
S G G G +G GG G K G PG EA G G QG +G+
Sbjct: 1573 GLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDL 1632
Query: 356 NMRNSETSPG 365
+ + PG
Sbjct: 1633 GEKGAVGFPG 1642
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 75.5 bits (184), Expect = 8e-14
Identities = 64/181 (35%), Positives = 83/181 (45%), Gaps = 16/181 (8%)
Query: 137 GHNGAWETSGGHGI-FGSQG--GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G +G+ GG G FG G GG G G G+ GY G+ G G G
Sbjct: 195 GRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDG--- 251
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG G + G+ G+ Q GYG+ + G + +G GGG GGGSGS G
Sbjct: 252 GYGGGGPGYSGGSRGYGSGGQ-GYGNQGSGYGGSGSYDSYNNGGGGGF---GGGSGSNFG 307
Query: 254 SSGSGSN-GDNNNGSSSGGSSSGSSSGGSSGGSSGG-----SSGNSGGSRGDSGSESSWG 307
GS ++ G+ NN SS+ G G + GG S G GG + + G G S S SS+G
Sbjct: 308 GGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367
Query: 308 S 308
S
Sbjct: 368 S 368
Score = 71.6 bits (174), Expect = 1e-12
Identities = 67/201 (33%), Positives = 77/201 (38%), Gaps = 36/201 (17%)
Query: 154 QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA 213
+ G G G G GG G G GN +G G G G GG GG G G
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGF---GGSRGGGGYGGS---GDGYNGFGN 249
Query: 214 QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSS 273
GYG GGG SGG G GSG G N GS GGS
Sbjct: 250 DGGYG-------------------GGGPGYSGGSRGY-----GSGGQGYGNQGSGYGGSG 285
Query: 274 SGSSSGGSSGGSSGGSSGNS---GGSRGDSGSESSWGSSTG-SSSGNHGG--SGGGNGHK 327
S S GG GG SG++ GGS D G+ ++ S+ G GN GG SG G
Sbjct: 286 SYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGG 345
Query: 328 PGCEKPGNEARGSGESGIQGF 348
KP N+ G S +
Sbjct: 346 QYFAKPRNQGGYGGSSSSSSY 366
Score = 62.4 bits (150), Expect = 7e-10
Identities = 49/134 (36%), Positives = 54/134 (40%), Gaps = 17/134 (12%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGS 254
Q G G NFG G G+G N N G G G S GGG G
Sbjct: 193 QRGRSGSGNFGGGRGG-----GFGG----NDNFGRGGNFSGRGGFGGSRGGGGYGG---- 239
Query: 255 SGSGSNGDNNNGSSSGGSS--SGSSSGGSSGGSSGGSSGNSGGSRG--DSGSESSWGSST 310
SG G NG N+G GG SG S G SGG G+ G+ G G DS + G
Sbjct: 240 SGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFG 299
Query: 311 GSSSGNHGGSGGGN 324
G S N GG G N
Sbjct: 300 GGSGSNFGGGGSYN 313
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/137 (32%), Positives = 55/137 (40%), Gaps = 9/137 (6%)
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
S SQ G SGSG+ G G G + G S G GGS G GG G + +G
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG-GGYGGSGDGYNGFG 248
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ--------GFRGQGVSSNMRN 359
+ G G G SGG G+ G + GN+ G G SG G G G SN
Sbjct: 249 NDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGG 308
Query: 360 SETSPGMFNFDTFWKNF 376
+ N++ NF
Sbjct: 309 GGSYNDFGNYNNQSSNF 325
Score = 60.1 bits (144), Expect = 3e-09
Identities = 43/131 (32%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSS-GGSSSGSSSGGSSGGSS--GGSSGNSGGS 296
GS N GGG G G + + G N +G GGS G GGS G + G G GG
Sbjct: 198 GSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGG 257
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G SG +GS G GN G GG+G G G G F G G ++
Sbjct: 258 PGYSGGSRGYGSG-GQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSG--SNFGGGGSYND 314
Query: 357 MRNSETSPGMF 367
N F
Sbjct: 315 FGNYNNQSSNF 325
Score = 52.0 bits (123), Expect = 9e-07
Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
S + S+ S G + +G+ GG G GG+ GG+ GG G G G
Sbjct: 182 SKQEMASASSSQRGRSGSGNFGGGR--GGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGG 239
Query: 308 SSTG-SSSGNHGG-SGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRN 359
S G + GN GG GGG G+ G G+ +G G G G+ G G + N
Sbjct: 240 SGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQG-SGYGGSGSYDSYNN 292
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 8/101 (7%)
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS--GSESSWGSSTGSSSGNH 317
NG N + +S+ S G SG SGN GG RG G+++ S G
Sbjct: 171 NGHNCEVRKALSKQEMASASSSQRGRSG--SGNFGGGRGGGFGGNDNFGRGGNFSGRGGF 228
Query: 318 GGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMR 358
GGS GG G+ G+ G G G G G G S R
Sbjct: 229 GGSRGGGGYGGS----GDGYNGFGNDGGYGGGGPGYSGGSR 265
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 75.1 bits (183), Expect = 1e-13
Identities = 80/267 (29%), Positives = 94/267 (35%), Gaps = 41/267 (15%)
Query: 123 HGADAVRGS--------------WQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGG 167
HG D +GS QG+PG G T G G G G G +G GN G
Sbjct: 737 HGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGA 796
Query: 168 LGTPWVHGYPGNSAGSFGMNPQGAPWG----QGGNGGPPNFGTN----------TQGAVA 213
G P G PG AG G + P G G G P + G N QG
Sbjct: 797 RGLPGPLGPPG-PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855
Query: 214 QPGY-GSVRASNQNEGCTNPPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
QPG G Q +P P G G G G G + G G G S+G
Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGG----GN 324
+G G G G G RGD GS G +G GG G G
Sbjct: 916 RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDR--GPAGPPGGPGDKGDPGE 973
Query: 325 GHKPGCEKPGNEARGSGESGIQGFRGQ 351
+PG + P A +G+ GI G GQ
Sbjct: 974 DGQPGPDGPPGPAGTTGQRGIVGMPGQ 1000
Score = 70.1 bits (170), Expect = 3e-12
Identities = 71/269 (26%), Positives = 93/269 (34%), Gaps = 26/269 (9%)
Query: 123 HGADAVRG-----SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGY 176
HG + V G QG PG G ++G G G G G G G PG G P + G
Sbjct: 887 HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGD 946
Query: 177 PGNSAGSFGMNPQGAPWGQGGNGGP-------PNFGTNTQGAVAQPGYGSVRASNQNEGC 229
PG+ P G P G G G P P+ G Q G + G
Sbjct: 947 PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM 1006
Query: 230 TN-PPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
P P+G+ G G + + G G GSNG G + + + G
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066
Query: 287 GGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGG-----GNGHKPGCEKPGNE 336
G G+ G GS+G G+ G+ + GS G G K G P
Sbjct: 1067 RGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP 1126
Query: 337 ARGSGESGIQGFRGQGVSSNMRNSETSPG 365
G+ G +G RGQ + PG
Sbjct: 1127 RGDKGDHGDRGDRGQKGHRGFTGLQGLPG 1155
Score = 69.7 bits (169), Expect = 4e-12
Identities = 70/262 (26%), Positives = 94/262 (35%), Gaps = 31/262 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG-- 190
G PG G G G G+ G LG +G+ GNPG G P + G PG + G P G
Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743
Query: 191 ---APWGQGGNGGPPNF----------GT----NTQGAVAQPGYGSVRASNQNEGCTNPP 233
P G G+ GPP GT +G + + G ++ G P
Sbjct: 744 GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPL 803
Query: 234 PSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
G + G G + GS G+ + +G + + +G G G
Sbjct: 804 GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863
Query: 294 G--GSRGDSGSESSWGSSTGSSSGNHGGSG-----GGNGHK--PGCEKPGNEARGSGESG 344
G G +GD+GS G S G HG +G GG G + PG A G G
Sbjct: 864 GEPGQKGDAGSPGPQG--LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921
Query: 345 IQGFRGQGVSSNMRNSETSPGM 366
G G E PG+
Sbjct: 922 PAGAPGPAGPLGEPGKEGPPGL 943
Score = 67.4 bits (163), Expect = 2e-11
Identities = 91/343 (26%), Positives = 121/343 (35%), Gaps = 50/343 (14%)
Query: 61 GAAGSKVSEALGQGTREAVGT-GVRQVPG----FGAADALGNRVGEAAHAL--------- 106
GA GSK EA G A+G G R +PG G A G R AH +
Sbjct: 315 GAPGSK-GEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQR---GAHGMPGKPGPMGP 370
Query: 107 ----------GNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGG 156
GN G + +A G + +G +G G G + G G G+ G
Sbjct: 371 LGIPGSSGFPGNPGMK--GEAGPTGARGPEGPQGQ-RGETGPPGPVGSPGLPGAIGTDGT 427
Query: 157 LGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNT------- 208
G +G G+PG G P G PG+ PQG GQ G+ G P F
Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR-GQPGDPGVPGFKGEAGPKGEPG 486
Query: 209 ----QGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
QG + PG R + G PP G+ + G GS G+ G+
Sbjct: 487 PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERG 546
Query: 265 NGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGG 322
SSG S G G+ G +G G +G G G+ GS G
Sbjct: 547 PVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG 606
Query: 323 GNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPG 365
G PG + G SG G G+ ++ + +PG
Sbjct: 607 IRGQPGSMGLPGPK----GSSGDPGKPGEAGNAGVPGQRGAPG 645
Score = 60.5 bits (145), Expect = 3e-09
Identities = 68/250 (27%), Positives = 90/250 (36%), Gaps = 22/250 (8%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSA--GS 183
+G PG +G SG G G G G QG QG PG G P G PG+ G
Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGD 700
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-NPPPSGSGGGSS 242
G P G+ GN G G PG + + +G +P PSG+ G +
Sbjct: 701 PGAVGPLGPRGERGNPGE----RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTG 756
Query: 243 NSG--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
G G G + + G GD G + + G G G +G + G+
Sbjct: 757 PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPT-GEK 815
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHK-----PGCEKPGNEARGSGESGIQGFRGQGVSS 355
G G S + GS G NG G + P + GE G G +G S
Sbjct: 816 GEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875
Query: 356 NMRNSETSPG 365
+ SPG
Sbjct: 876 GPQGLAGSPG 885
Score = 57.0 bits (136), Expect = 3e-08
Identities = 63/234 (26%), Positives = 79/234 (33%), Gaps = 28/234 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNS------------ 180
G PG G G G+ G +G G G+ G G G P G PG
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659
Query: 181 --AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
AG G P G G GPP G +PG V G P
Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPP----GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN 715
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G G +G +G +G + S G S + +G G G +G G
Sbjct: 716 PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP 775
Query: 297 RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
+GD G G+ ++GN G G PG P A +GE G G RG
Sbjct: 776 KGDRGGIGEKGAE--GTAGNDGARG-----LPGPLGPPGPAGPTGEKGEPGPRG 822
Score = 55.1 bits (131), Expect = 1e-07
Identities = 66/245 (26%), Positives = 83/245 (33%), Gaps = 21/245 (8%)
Query: 107 GNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNP 165
GNT GR+ + +G VP G G G GSQG G +G +G P
Sbjct: 103 GNTNFGRGRKGQ----------KGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRP 152
Query: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
G G + G PG P G P G +G F G + G GS
Sbjct: 153 GPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGL-- 210
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS 285
P S G G G Q G+ +G G+ + G S G
Sbjct: 211 ------MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264
Query: 286 SGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
G G + G+ G+ G S G+ + G G GHK G E P E G G
Sbjct: 265 EDGEPGRN-GNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHK-GLEGPKGEVGAPGSKGE 322
Query: 346 QGFRG 350
G G
Sbjct: 323 AGPTG 327
Score = 52.8 bits (125), Expect = 6e-07
Identities = 63/224 (28%), Positives = 75/224 (33%), Gaps = 27/224 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGN--SAGSFGMNPQG 190
G PG G +G G G G G G G PG G G PG + G G
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250
P G G+ G P T G V PG R + G PP G + G G
Sbjct: 1074 GPAGLPGSQGAPG----TPGPVGAPGDAGQRGDPGSRGPIGPP------GRAGKRGLPGP 1123
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGS 308
Q G +GD + G G G G++G G G G G
Sbjct: 1124 QGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGP 1183
Query: 309 STGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GESGIQGFRGQ 351
S G G G PG RGS GE+G +G G+
Sbjct: 1184 S---------GKEGNPGPLGPIGPPG--VRGSVGEAGPEGPPGE 1216
Score = 49.3 bits (116), Expect = 6e-06
Identities = 83/321 (25%), Positives = 108/321 (33%), Gaps = 23/321 (7%)
Query: 19 GEAGPL-QSGEESTGTNIGEALGHG-LGDALSEGVGKAIGKEAG----GAAG--SKVSEA 70
G AGPL + G+E G+ HG +GD G G + G G A
Sbjct: 927 GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPA 986
Query: 71 LGQGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALGNTGHE--IGRQAED--VIR 122
G R VG G R +PG +VG A G+ G +G + V
Sbjct: 987 GTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG-ATGDKGPPGPVGPPGSNGPVGE 1045
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSA 181
G + G+ G PG +GA G G G G G QG G PG +G P G G+
Sbjct: 1046 PGPEGPAGN-DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPG 1104
Query: 182 GSFGMNPQGAPWGQGGNGGP--PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG 239
+ P G G+ G GP P G G R +G PP
Sbjct: 1105 SRGPIGPPGRA-GKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
GS+ G G + G +G N G G G G G G
Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP-GPPGP 1222
Query: 300 SGSESSWGSSTGSSSGNHGGS 320
G ++ G G++ S
Sbjct: 1223 PGPPGHLTAALGDIMGHYDES 1243
Score = 36.2 bits (82), Expect = 0.053
Identities = 53/200 (26%), Positives = 67/200 (33%), Gaps = 30/200 (15%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPP----PSGSGGGSSNSG---- 245
Q GG NFG +G +PG V + G PP P G G G
Sbjct: 98 QTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGP 157
Query: 246 -------------GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
G G S G +G + S+ S GS G GS G
Sbjct: 158 QGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVG- 216
Query: 293 SGGSRGDSGSESSWGSS--TG--SSSGNHGGSG--GGNGHKPGCEKPGNEARGSGESGIQ 346
G RG G + G + TG G+ G G G G + KPG + G +G
Sbjct: 217 PVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGE-PGRNGNP 275
Query: 347 GFRGQGVSSNMRNSETSPGM 366
G G S R +PG+
Sbjct: 276 GEVGFAGSPGARGFPGAPGL 295
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 75.1 bits (183), Expect = 1e-13
Identities = 107/395 (27%), Positives = 152/395 (38%), Gaps = 67/395 (16%)
Query: 27 GEESTGTNIGEALGHG--LGDAL--SEGVGKAIGKEA------------GGAAGSKVSEA 70
G STG G AL G L S G G A+ A GG+ G+ VS
Sbjct: 961 GSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFG 1020
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAE-------DVIRH 123
T G V FG + G + G + A
Sbjct: 1021 SALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFS 1080
Query: 124 GADAVRGSWQGVP----GHNGAWETSGGHG-IFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
GA + + G P G GA+ TS G G + GG + G P G
Sbjct: 1081 GAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFG 1140
Query: 179 NSAGS---FGMNPQGAP-WGQGGN-----GGPPNFGTNTQGAVAQPGY--GSVRASNQNE 227
+ G+ FG P + +G N GGPP+ GA + P + G ++ +
Sbjct: 1141 GAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATS-PSFCDGPSTSTGFSF 1199
Query: 228 GCTNPPPSGSGGGSSNS---GGGSGSQSGSSG---SGSNGDNNNGSSSG-GSSSGSSSG- 279
G +G GGG + S GGG G+ +G SG + S D G+S+G G G+S+G
Sbjct: 1200 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 1259
Query: 280 ----GSSGGSSGGSSGNSG---------GSRGDSGSESSWGSSTGSSSGNHGG--SGGGN 324
G+S G SGG ++G G G G+ +S+GS+ G+S+G GG + G
Sbjct: 1260 GGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGF 1319
Query: 325 GHKPGCEKPGNEAR----GSGESGIQGFRGQGVSS 355
G +P + GSG + GF G+ +S
Sbjct: 1320 GSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTS 1354
Score = 72.0 bits (175), Expect = 9e-13
Identities = 81/231 (35%), Positives = 92/231 (39%), Gaps = 29/231 (12%)
Query: 137 GHNGAWETSGGHGI-FGSQGGLGG---QGQGNPGGLGTP-WVHGYPGNSAGSFGMNPQGA 191
G G TS G G G+ G G G GGLGT G PG S G FG +
Sbjct: 1208 GFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTG-FGGGLGTS 1266
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
GG G FG G V G+G +N + G T +G GG S S G GS+
Sbjct: 1267 AGFSGGLGTSAGFGG---GLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTS-DGFGSR 1322
Query: 252 SGSS-----------GSGSN---GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
+S GSGSN G S+S G SSG S S G SGG S G
Sbjct: 1323 PNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPS---SIVGFSGGPSTGVGFCS 1379
Query: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
G S S S G STG+ G GG G G G G+ G GF
Sbjct: 1380 GPSTSGFSGGPSTGAGFG--GGPNTGAGFGGGPSTSAGFGSGAASLGACGF 1428
Score = 63.5 bits (153), Expect = 3e-10
Identities = 96/317 (30%), Positives = 115/317 (36%), Gaps = 48/317 (15%)
Query: 13 ALCLGSGEAGPLQ-SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEAL 71
+LC GS L G ST A D S G + G
Sbjct: 1156 SLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGN-------------- 1201
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G T G G+ GFG LG G + ++G + G G A G
Sbjct: 1202 GLSTNAGFGGGLNTSAGFGGG--LGTSAGFSGGLSTSSGFDGGL--------GTSAGFGG 1251
Query: 132 WQGVP-GHNGAWETSGGH-GIFGSQGGLGG---QGQGNPGGLGTPWVHGYP-GNSAGSFG 185
G G G TS G G G+ G GG G GGLGT G G SAG
Sbjct: 1252 GPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGF-- 1309
Query: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
G G G PN + +G G+GS SN + G T P + +G S
Sbjct: 1310 ---SGGLSTSDGFGSRPNASFD-RGLSTIIGFGS--GSNTSTGFTGEPSTSTGFSS---- 1359
Query: 246 GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G S G SG S G G SG S+SG S GG S G+ G N+G G S S+
Sbjct: 1360 -GPSSIVGFSGGPSTGV---GFCSGPSTSGFS-GGPSTGAGFGGGPNTGAGFGGGPSTSA 1414
Query: 306 WGSSTGSSSGNHGGSGG 322
S +S G G S G
Sbjct: 1415 GFGSGAASLGACGFSYG 1431
Score = 60.5 bits (145), Expect = 3e-09
Identities = 90/335 (26%), Positives = 127/335 (37%), Gaps = 27/335 (8%)
Query: 13 ALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEA--GGAAGSKVSEA 70
A +G G L + + GT ++G G + S G A G GGA + +
Sbjct: 1102 AFSTSAGFGGALSTAADFGGTP-SNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFG 1160
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130
T G F A + G + + G+ + A A G
Sbjct: 1161 SASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFG 1220
Query: 131 SWQGVP-GHNGAWETSGGH-GIFGSQGGLGG---QGQGNPGGLGTP-WVHGYPGNSAGSF 184
G G +G TS G G G+ G GG G GGLGT G G SAG
Sbjct: 1221 GGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFG 1280
Query: 185 GMNPQGAPWGQGGNGGPPNFGTN-------TQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237
G +G GG G +FG+ + G G+GS ++ + G + G
Sbjct: 1281 GGLVTSDGFG-GGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI--IGF 1337
Query: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG-------SSSGGSSGGSSGGSS 290
G GS+ S G +G S S+G S+G ++ SGG S+G S+SG S G S+G
Sbjct: 1338 GSGSNTSTGFTGEPSTSTGF-SSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGF 1396
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
G + G S + GS + + G G G
Sbjct: 1397 GGGPNTGAGFGGGPSTSAGFGSGAASLGACGFSYG 1431
Score = 40.0 bits (92), Expect = 0.004
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 190 GAPWGQGGNGGPPNFGTNTQGA-VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
G+P G GG + G+ G+G +++ + G ++ + GG S S
Sbjct: 901 GSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFD 960
Query: 249 GSQSGSSGSGSNGDNNNGSSSGG---SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
GS S +G+G G N +S G +S+G S+ GG+ S G G+ S
Sbjct: 961 GSPS--TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVS 1018
Query: 306 WGSSTGSSSGNHGGSGGGN 324
+GS+ +++G +GG+ N
Sbjct: 1019 FGSALNTNAG-YGGAVSTN 1036
Score = 39.7 bits (91), Expect = 0.005
Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 25/143 (17%)
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258
GG P + G V+ G + S G + SG GG S + G SG S S+ G
Sbjct: 814 GGMPCTSASFSGGVSSSFSGPLSTSATFSGGAS---SGFGGTLSTTAGFSGVLSTSTSFG 870
Query: 259 SNGDNNNGSSS------------------GGSSSGSSSGGSSGGSS---GGSSGNSGGSR 297
S + SS GGS S S S G + +S GGS S G
Sbjct: 871 SAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFG 930
Query: 298 GDSGSESSWGSSTGSSSGNHGGS 320
G + S+G S+ S+S N GG+
Sbjct: 931 GTLSTSVSFGGSS-STSANFGGT 952
Score = 39.7 bits (91), Expect = 0.005
Identities = 40/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 199 GGPPNFGTNTQGAVA-QPGYGSVRASNQNEGCTNPPPSGSGGGS-SNSGGGSGSQSGSSG 256
G P T A++ G+G + +++ G +P SGS GG+ S S GS S+G
Sbjct: 870 GSAPTTSTVFSSALSTSTGFGGILSTSVCFG-GSPSSSGSFGGTLSTSICFGGSPCTSTG 928
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSS---GGSSGNSGGSRGDSGSESSWGSSTGSS 313
G G + S GGSSS S++ G + +S GS G G + +S+GS +S
Sbjct: 929 FG--GTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTS 986
Query: 314 SGNHG 318
+G G
Sbjct: 987 TGFGG 991
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Query: 231 NPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS-SSGGSSSGSSSGGSSGGSSGGS 289
N PS SGG GG G G + S S +N S S GG+ S SSS S+ S G
Sbjct: 742 NGAPSSSGG----FSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGC 797
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
+ ++ S S S G S+S + G S +G
Sbjct: 798 AHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSG 833
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/138 (28%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
GAP GG G P T G ++ + G T S +S S G +
Sbjct: 743 GAPSSSGGFSGGPGI---TFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAH 799
Query: 250 SQSGSSGS------GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG----SRGD 299
S S S S G + S G SSS S +S SGG+S GG + G
Sbjct: 800 STSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGF 859
Query: 300 SG---SESSWGSSTGSSS 314
SG + +S+GS+ +S+
Sbjct: 860 SGVLSTSTSFGSAPTTST 877
Score = 28.9 bits (63), Expect = 8.5
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS--SGGSSGNSGGSRGDSGSESSWGSSTG 311
S G+ + ++G+S + + SSSGG SGG + G + ++ S ++ S S G+ +
Sbjct: 724 SRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLST 783
Query: 312 SSSGNHGGS 320
SSS + S
Sbjct: 784 SSSFSSAAS 792
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 74.7 bits (182), Expect = 1e-13
Identities = 83/301 (27%), Positives = 106/301 (35%), Gaps = 34/301 (11%)
Query: 73 QGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAV 128
QG R GT G + + G D L + G A G G E G E+ G
Sbjct: 162 QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPG----APGVKG-EPGAPGEN----GTPGQ 212
Query: 129 RGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPWVHGYPG-----NSAG 182
G+ +G+PG G G G GS G +G G P G G P G PG + G
Sbjct: 213 TGA-RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271
Query: 183 SFGMNPQGAPWGQ------GGNGGPP-----NFGTNTQGAVAQPGYGSVRASNQNEGCTN 231
+ G P G+ G GPP N T +GA PG G
Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
P + G+ G G SG+ G+ + G G GS+G
Sbjct: 332 PVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391
Query: 292 NSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFR 349
G G RG GS G+ + GS G +G G P +A GE G+ G R
Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASG-PAGVRGPNGDAGRPGEPGLMGPR 450
Query: 350 G 350
G
Sbjct: 451 G 451
Score = 72.0 bits (175), Expect = 9e-13
Identities = 100/336 (29%), Positives = 121/336 (36%), Gaps = 53/336 (15%)
Query: 47 LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT-GVRQVPG-FGAADALGNR--VGEA 102
LS VG A G G+K + L G A G G R +PG GAA A G R VGE
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGL-PGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348
Query: 103 AHALGNTGHEIGRQAE--------------DVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
A G+ G E G + E + + G + GS G PG G + G
Sbjct: 349 GPA-GSKG-ESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS-AGPPGPPGLRGSPGSR 405
Query: 149 GIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFG----MNPQGAPWGQGGNGGPPN 203
G+ G+ G G G G+ G G V G P AG G M P+G P G GN GP
Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLP-GSPGNIGP-- 461
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG--GGSGSQSGSSGSGSNG 261
+G V PG P P G G G G G + + G NG
Sbjct: 462 --AGKEGPVGLPGIDG-----------RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNG 508
Query: 262 DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGG 319
D + +G + G + G G G G +G G G S G
Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568
Query: 320 SGGGNG-----HKPGCEKPGNEARGSGESGIQGFRG 350
G G PG P E GESG G G
Sbjct: 569 KPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTG 604
Score = 69.7 bits (169), Expect = 4e-12
Identities = 86/309 (27%), Positives = 116/309 (37%), Gaps = 27/309 (8%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G R PG A +G + G G + + V+ A G+PG GA
Sbjct: 589 GERGPPGESGAAGPTGPIGSRGPS-GPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647
Query: 142 WETSGGHGIFGS---QGGLGGQGQ----GNPGGLGTPWVHGYPGN--SAGSFG----MNP 188
GG G G +G +G G+ G PG +G P G G+ AG+ G P
Sbjct: 648 AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707
Query: 189 QGAPWGQGGNGGP--PNFGTNTQGAVAQPGYGSVRASNQNEGCTN-PPPSGSGGGSSNSG 245
+G+P G+ G GP PN GA QPG R + +G P+G G + +G
Sbjct: 708 RGSP-GERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAG 766
Query: 246 -GGSGSQSGSSGSGS-NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSG 301
G +GS G G G ++G + SG S G +G G G RGD G
Sbjct: 767 PNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826
Query: 302 SESSWGS----STGSSSGNHGGSG-GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
G +G G SG G PG P G G+ G RG+
Sbjct: 827 PVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPG 886
Query: 357 MRNSETSPG 365
+ + PG
Sbjct: 887 VAGAVGEPG 895
Score = 68.6 bits (166), Expect = 1e-11
Identities = 115/430 (26%), Positives = 152/430 (35%), Gaps = 85/430 (19%)
Query: 18 SGEAGPL-------QSGEESTGTNIGE-ALGHGLGDALSEGVGKAIGKE-AGGAAGSKVS 68
SG AGP SG N GE + +G A G G+ A G G K
Sbjct: 597 SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK-G 655
Query: 69 EALGQGTREAVGT----GVRQVPGF----GAADALGNRVGEAAHA--------LGNTGH- 111
E G R +G G R PG G A A G+R GEA A G+ G
Sbjct: 656 EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDR-GEAGAAGPAGPAGPRGSPGER 714
Query: 112 -EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-- 168
E+G + A A G G GA G +G+ G G +G G P G
Sbjct: 715 GEVGPAGPNGFAGPAGAA--GQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772
Query: 169 --------GTPWVHGYPGNSAGSFGMNPQG--------APWGQGGNGGP-----PNFGTN 207
G P + G+PG + + P G P G+ G GP P T
Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPP----PSGSGGGSSNSG-GGSGSQSGSSG-SGSNG 261
GAV PG+ + + G PP P G G G GS + G G +G+ G
Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892
Query: 262 D-------NNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSG--------GSRGDSGSES 304
+ G+ + GS + G +G G+ GN G G +G+ G
Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952
Query: 305 SWGS-STGSSSGNHG--GSGGGNGHK-----PGCEKPGNEARGSGESGIQGFRGQGVSSN 356
+ G + G HG G G +G++ G P G SG QG RG
Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012
Query: 357 MRNSETSPGM 366
+ PG+
Sbjct: 1013 EKGPRGLPGL 1022
Score = 62.4 bits (150), Expect = 7e-10
Identities = 74/266 (27%), Positives = 98/266 (36%), Gaps = 33/266 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G GH G G G+ G QG G G G PG G +G G +G P
Sbjct: 142 GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEP 201
Query: 193 WGQGGNGGPPNFGTN----TQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGG-------- 239
G NG P G +G V PG R S+ + G P P GS G
Sbjct: 202 GAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAP 261
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG--GSSGNS 293
G G G+ + +G G+ SG G + G +G G++G G +G
Sbjct: 262 GPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAP 321
Query: 294 G--GSRGDSGSESSWGSSTGSSSGNHGGSGG-----GNGHKPGCEKPGNEARGSGESGIQ 346
G G RG G + G++ G G GN +PG P SGE G +
Sbjct: 322 GLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKR 381
Query: 347 GFRGQGVSS------NMRNSETSPGM 366
G G+ S+ +R S S G+
Sbjct: 382 GPNGEAGSAGPPGPPGLRGSPGSRGL 407
Score = 62.0 bits (149), Expect = 9e-10
Identities = 67/255 (26%), Positives = 90/255 (35%), Gaps = 23/255 (9%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSA--GS 183
+G PG +G G G G QGG G QG QG PG G G PG G
Sbjct: 519 RGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578
Query: 184 FGM----NPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSG 236
FG+ P+G P G+ G GP ++G PG + G PSG
Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTG-PIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSG 637
Query: 237 SGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
G G + G G + G G+ N G + + G + G G +G
Sbjct: 638 PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAG 697
Query: 295 --GSRGDSGSESSWG--SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRG 350
G G +G S G G + N G +PG + GE+G+ G G
Sbjct: 698 AAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTG 757
Query: 351 QGVSSNMRNSETSPG 365
++ PG
Sbjct: 758 PVGAAGPAGPNGPPG 772
Score = 59.7 bits (143), Expect = 5e-09
Identities = 68/229 (29%), Positives = 86/229 (37%), Gaps = 31/229 (13%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGT---PWVHGYPGNSAGSFGM 186
G PG G G G+ GS+G G G G PG LG P G PG + GS G+
Sbjct: 859 GTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPG-AVGSPGV 917
Query: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG- 245
N GAP G +G P N G G QPG+ R N G P G+ G G
Sbjct: 918 N--GAPGEAGRDGNPGNDG--PPGRDGQPGHKGERGYPGNIG-----PVGAAGAPGPHGP 968
Query: 246 -GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGS 302
G +G +G +G + G G G G G G +G +G
Sbjct: 969 VGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGL 1028
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQ 351
+ G +G+HG G PG P +G SG G G+
Sbjct: 1029 QGLPG-----IAGHHGDQGA-----PGSVGPAGPRGPAGPSGPAGKDGR 1067
Score = 55.8 bits (133), Expect = 7e-08
Identities = 58/259 (22%), Positives = 88/259 (33%), Gaps = 29/259 (11%)
Query: 134 GVPGHNGAWETS-GGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGY---------PGNSAG 182
G PG G + G G+ G +G G +G PG G P G+ PG +
Sbjct: 69 GPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGP 128
Query: 183 SFGMNPQGAPWGQGGNGG--------------PPNFGTNTQGAVAQPGYGSVRASNQNEG 228
+ P G P G+ G G P G PG+ +R N +G
Sbjct: 129 AGARGPAGPP-GKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDG 187
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
P + G + G +G+ + G G+ + G + + S G G
Sbjct: 188 LKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAG 247
Query: 289 SSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
G++G G G G + G+ + G G G PG P G +G+
Sbjct: 248 PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG-LPGLSGPVGPPGNPGANGLT 306
Query: 347 GFRGQGVSSNMRNSETSPG 365
G +G + + PG
Sbjct: 307 GAKGAAGLPGVAGAPGLPG 325
Score = 52.4 bits (124), Expect = 7e-07
Identities = 67/264 (25%), Positives = 80/264 (30%), Gaps = 41/264 (15%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
E+ +R G RG G G G G G G G G P GLG + Y
Sbjct: 27 EETVRKGPAGDRGP----RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82
Query: 178 GNSAGSFGMNPQG-----APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232
G G G P G P G G GP F QG +PG G P
Sbjct: 83 GKGVG-LGPGPMGLMGPRGPPGAAGAPGPQGF----QGPAGEPGEPGQTGPAGARGPAGP 137
Query: 233 PPSGSGGGSSNSGGGSGSQ-----SGSSG----------SGSNGDNNNGSSSGGSSSGSS 277
P G G G + G+ G G G N G +
Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 197
Query: 278 SGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
G G+ G +G G+ G +G+ S GS GS G G
Sbjct: 198 KGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF 257
Query: 327 KPGCEKPGNEARGSGESGIQGFRG 350
PG P E G +G G G
Sbjct: 258 -PGAPGPKGEIGAVGNAGPAGPAG 280
Score = 47.4 bits (111), Expect = 2e-05
Identities = 78/283 (27%), Positives = 97/283 (34%), Gaps = 18/283 (6%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
+GE GP SGE T G GL G G+ + G+ V E G
Sbjct: 843 AGEKGP--SGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGI- 899
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
A G R PG + + GEA GN G++ G D + G RG + G
Sbjct: 900 -AGPPGARGPPGAVGSPGVNGAPGEAGRD-GNPGND-GPPGRDG-QPGHKGERG-YPGNI 954
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G GA G HG G G G +G+ P G +G G G S +G P +
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG-----GGSG 249
G G P G N G PG G P P G G S +G G G
Sbjct: 1015 GPRGLPGLKGHN--GLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
+ + G G G G S GG G G+
Sbjct: 1073 TVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGD 1115
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.131 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,598,459
Number of Sequences: 37866
Number of extensions: 1356712
Number of successful extensions: 49371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 942
Number of HSP's successfully gapped in prelim test: 625
Number of HSP's that attempted gapping in prelim test: 8299
Number of HSP's gapped (non-prelim): 13091
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.