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Search of human proteins with 59939900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 686 0.0
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 645 0.0
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 503 e-142
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 493 e-140
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 485 e-137
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 465 e-131
gi|45594240 limbic system-associated membrane protein [Homo sapi... 353 2e-97
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 316 2e-86
gi|157819143 IgLON family member 5 [Homo sapiens] 312 2e-85
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 108 9e-24
gi|109150416 peroxidasin [Homo sapiens] 100 2e-21
gi|118572606 hemicentin 1 [Homo sapiens] 100 3e-21
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 98 9e-21
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 98 9e-21
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 98 9e-21
gi|110349719 titin isoform N2-A [Homo sapiens] 97 2e-20
gi|126517478 peroxidasin homolog-like [Homo sapiens] 96 5e-20
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 96 6e-20
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 93 4e-19
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 93 4e-19
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 92 5e-19
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 92 5e-19
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 92 7e-19
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 92 9e-19
gi|205277425 immunoglobulin superfamily, member 9 isoform a [Hom... 87 2e-17
gi|205277423 immunoglobulin superfamily, member 9 isoform b [Hom... 87 3e-17
gi|7657359 contactin 5 isoform long [Homo sapiens] 86 5e-17
gi|28373129 contactin 5 isoform short [Homo sapiens] 86 5e-17
gi|4827022 contactin 2 precursor [Homo sapiens] 86 6e-17
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 86 6e-17
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 686 bits (1769), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA 60
MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA
Sbjct: 1 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA 60
Query: 61 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 120
WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR
Sbjct: 61 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 120
Query: 121 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL 180
VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL
Sbjct: 121 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL 180
Query: 181 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 240
EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS
Sbjct: 181 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 240
Query: 241 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA
Sbjct: 241 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
Query: 301 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF
Sbjct: 301 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 645 bits (1665), Expect = 0.0
Identities = 322/331 (97%), Positives = 322/331 (97%)
Query: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
VV S L GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI
Sbjct: 15 VVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 74
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV
Sbjct: 75 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
Query: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 187
PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR
Sbjct: 135 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 194
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 247
DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF
Sbjct: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 254
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP 307
QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP
Sbjct: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP 314
Query: 308 GAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
GAVIDGVNSASRALACLWLSGTLLAHFFIKF
Sbjct: 315 GAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 503 bits (1294), Expect = e-142
Identities = 242/338 (71%), Positives = 280/338 (82%), Gaps = 1/338 (0%)
Query: 1 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA 60
M++ W +F+ AL GVPVRSGDATFPKAMDNVTVRQGESATLRCTID+RVTRVA
Sbjct: 8 MHNSISWAIFTGLAALCLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVA 67
Query: 61 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 120
WLNRSTILYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTDNHPKTSR
Sbjct: 68 WLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSR 127
Query: 121 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL 180
VHLIVQV P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GFVSEDEYL
Sbjct: 128 VHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGFVSEDEYL 186
Query: 181 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 240
EI I R+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG L CEAS
Sbjct: 187 EIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEAS 246
Query: 241 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
AVP AEFQW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+NKLG+TNA
Sbjct: 247 AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNA 306
Query: 301 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
SI L+GPGAV + N SR C+WL L+ H +KF
Sbjct: 307 SIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 344
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 493 bits (1270), Expect = e-140
Identities = 241/331 (72%), Positives = 275/331 (83%), Gaps = 1/331 (0%)
Query: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
VV S L GVPVRSGDATFPKAMDNVTVRQGESATLRCTID+RVTRVAWLNRSTI
Sbjct: 15 VVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTI 74
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
LYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV
Sbjct: 75 LYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
Query: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 187
P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GFVSEDEYLEI I R
Sbjct: 135 SPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGFVSEDEYLEIQGITR 193
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 247
+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG L CEASAVP AEF
Sbjct: 194 EQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEF 253
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP 307
QW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+NKLG+TNASI L+GP
Sbjct: 254 QWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGP 313
Query: 308 GAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
GAV + N SR C+WL L+ H +KF
Sbjct: 314 GAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 344
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 485 bits (1248), Expect = e-137
Identities = 241/342 (70%), Positives = 275/342 (80%), Gaps = 12/342 (3%)
Query: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
VV S L GVPVRSGDATFPKAMDNVTVRQGESATLRCTID+RVTRVAWLNRSTI
Sbjct: 15 VVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTI 74
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
LYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV
Sbjct: 75 LYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
Query: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 187
P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GFVSEDEYLEI I R
Sbjct: 135 SPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGFVSEDEYLEIQGITR 193
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 247
+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG L CEASAVP AEF
Sbjct: 194 EQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEF 253
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY-- 305
QW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+NKLG+TNASI L+
Sbjct: 254 QWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFEV 313
Query: 306 ---------GPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
GPGAV + N SR C+WL L+ H +KF
Sbjct: 314 KTTALTPWKGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 355
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 465 bits (1196), Expect = e-131
Identities = 227/299 (75%), Positives = 257/299 (85%), Gaps = 1/299 (0%)
Query: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
VV S L GVPVRSGDATFPKAMDNVTVRQGESATLRCTID+RVTRVAWLNRSTI
Sbjct: 15 VVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTI 74
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
LYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV
Sbjct: 75 LYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
Query: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 187
P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GFVSEDEYLEI I R
Sbjct: 135 SPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGFVSEDEYLEIQGITR 193
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 247
+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG L CEASAVP AEF
Sbjct: 194 EQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEF 253
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG 306
QW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+NKLG+TNASI L+G
Sbjct: 254 QWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFG 312
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 353 bits (905), Expect = 2e-97
Identities = 171/306 (55%), Positives = 235/306 (76%), Gaps = 5/306 (1%)
Query: 21 GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPR 80
G+PVRS D F + DN+TVRQG++A LRC ++D+ ++VAWLNRS I++AG+DKWS+DPR
Sbjct: 26 GLPVRSVD--FNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPR 83
Query: 81 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV 140
V + +YS+ IQ VDVYDEG YTCSVQT + PKTS+V+LIVQVPP+I NISSD+TV
Sbjct: 84 VELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTV 143
Query: 141 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALND 200
NEGS+VTL+C+A GRPEP +TWRHL+ G+ F E+EYLEI I R+QSG+YEC A N+
Sbjct: 144 NEGSNVTLVCMANGRPEPVITWRHLT-PTGREFEGEEEYLEILGITREQSGKYECKAANE 202
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
V++ DV++VK+TVNYPP I+++K+ + G++ L CEASAVP +F+W++++TR+ +
Sbjct: 203 VSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSA- 261
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRA 320
+G+ I++ S+LT NV+E+ YGNYTCVA NKLG TNAS+ L+ PG+V G+N +
Sbjct: 262 NGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSV-RGINGSISL 320
Query: 321 LACLWL 326
LWL
Sbjct: 321 AVPLWL 326
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 316 bits (809), Expect = 2e-86
Identities = 156/329 (47%), Positives = 215/329 (65%), Gaps = 3/329 (0%)
Query: 7 WVVFSATTALLFIPGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS 65
W+ + +P FP A+DN+ VR+G++A LRC ++D ++ AWLNRS
Sbjct: 16 WLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
Query: 66 TILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 125
+I++AG DKWS+DPRV I YS+ IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
Query: 126 QVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDI 185
QVPP+I +IS+D+TVNEG++VTL CLA G+PEP+++WRH+S +YL+I I
Sbjct: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKP--FENGQYLDIYGI 193
Query: 186 KRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMA 245
RDQ+GEYECSA NDV+ PDVRKVK+ VN+ P I + K+ V+ G+ G++ CE + VP
Sbjct: 194 TRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP 253
Query: 246 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
F+W+K E +L G G+ I+N S LT NV+++ +GNYTCVA NKLG TNAS+ L
Sbjct: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
Query: 306 GPGAVIDGVNSASRALACLWLSGTLLAHF 334
P G+ ++ L W L+ F
Sbjct: 314 PPSTAQYGITGSADVLFSCWYLVLTLSSF 342
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 312 bits (800), Expect = 2e-85
Identities = 162/302 (53%), Positives = 213/302 (70%), Gaps = 9/302 (2%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 90
F DN TV +G++ATL C ID+ VTRVAWLNRS ILYAGND+W+ DPRV +L+NTP +
Sbjct: 35 FNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEE 94
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 150
+SI+I V + DEG YTCS QT + P T++V+LIV VP +I+NISS +TVNEG +V LLC
Sbjct: 95 FSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLC 154
Query: 151 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-AAPDVRKV 209
LA+GRPEPTVTWR L GF SE E LEISDI+R Q+GEYEC N V +APD R+V
Sbjct: 155 LAVGRPEPTVTWRQLR----DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
Query: 210 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL-DGMRIENK 268
+TVNYPP I+ + ++G+ +L CEA AVP A+FQW+K++ L++G +G++++ +
Sbjct: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRALACLWLSG 328
S L F NVS + YGNYTC A N+LG ++AS+ L PG++ NSA R L L
Sbjct: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSL---ENSAPRPPGLLALLS 327
Query: 329 TL 330
L
Sbjct: 328 AL 329
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 108 bits (269), Expect = 9e-24
Identities = 90/305 (29%), Positives = 133/305 (43%), Gaps = 38/305 (12%)
Query: 38 VTVRQGESATLRCTIDDRVTR------VAWLNRST----ILYAGNDKWSIDPRVIILVNT 87
VT R GES LRC + VT V W + G +DP +
Sbjct: 33 VTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASL 92
Query: 88 PTQYSIMIQNVDVYDEGPYTCSV-----QTDNHPKTSRVHLIVQVPPQIMNISSD-ITVN 141
+ S+ ++ V D+G Y C V Q D S VHL + PP I
Sbjct: 93 HDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAK 152
Query: 142 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 195
EG S+T+ C A G P+P VTW +KEG + +Y L ++ + R+ G Y C
Sbjct: 153 EGGSITMTCTAFGNPKPIVTW----LKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTC 208
Query: 196 SALNDVAAPDVRKVKITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAEFQWFKEE 253
A + + V + V PP+I S +N V++ Q +L+C A A P + W+ ++
Sbjct: 209 RAYS-IQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQD 267
Query: 254 TRLATGLD---GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG---NTNASITLYGP 307
+ D +RI G TL F V +D G YTCV +N LG + +A +T+ P
Sbjct: 268 ENVYFQNDLKLRVRILIDG---TLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYP 324
Query: 308 GAVID 312
V++
Sbjct: 325 ARVLN 329
Score = 74.7 bits (182), Expect = 1e-13
Identities = 75/278 (26%), Positives = 110/278 (39%), Gaps = 31/278 (11%)
Query: 38 VTVRQGESATLRCT-IDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
+ ++G S T+ CT + V WL T+L A K+ + + S+ +
Sbjct: 149 IEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASG-KYQV-----------SDGSLTVT 196
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 156
+V D G YTC + HL+VQ PP I++ +ITVN L C A P
Sbjct: 197 SVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYP 256
Query: 157 -EPTVTWRHLSVKEGQGFVSE---------DEYLEISDIKRDQSGEYECSALNDVAAPDV 206
T TW E F ++ D L I +K + SG+Y C N +
Sbjct: 257 GNLTYTWYWQD--ENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPS 314
Query: 207 RKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAE-FQWFKEETRLATGLD-GM 263
+TV YP ++ V VG G + C A P A +W K+ L + G
Sbjct: 315 ASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGW 374
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 301
+ G ++ +E+ G YTCV N LG S
Sbjct: 375 TLMEDG---SIRIEEATEEALGTYTCVPYNTLGTMGQS 409
Score = 66.2 bits (160), Expect = 4e-11
Identities = 74/295 (25%), Positives = 121/295 (41%), Gaps = 34/295 (11%)
Query: 36 DNVTVRQGESATLRCTIDDRVTRVA--WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSI 93
+N+TV + A L C + + W + +Y ND + RV IL++ ++
Sbjct: 236 ENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQND---LKLRVRILIDG----TL 288
Query: 94 MIQNVDVYDEGPYTC--SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
+I V D G YTC S P S +L VQ P +++N+ I V G + C
Sbjct: 289 IIFRVKPEDSGKYTCVPSNSLGRSPSAS-AYLTVQYPARVLNMPPVIYVPVGIHGYIRCP 347
Query: 152 AIGRPEPTVT-W----RHLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAP- 204
P TV W R L V++ G+ + ED + I + + G Y C N +
Sbjct: 348 VDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMG 407
Query: 205 DVRKVKITVNYPPYISKAKNTGV--SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
++ + PPY + G++ ++ C A+ P W K G
Sbjct: 408 QSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRK------VGKPS 461
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-------YGPGAV 310
+ +L F +S++D+G + CVATN + + AS L + PG+V
Sbjct: 462 RSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSV 516
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 100 bits (249), Expect = 2e-21
Identities = 90/297 (30%), Positives = 121/297 (40%), Gaps = 37/297 (12%)
Query: 21 GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDP 79
G P R TF N V GES TL C+ R++W +DP
Sbjct: 337 GSPARP---TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR------GDRTPLPVDP 387
Query: 80 RVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDIT 139
RV I TP+ + IQNV D G Y CS + + +IVQ PQ D
Sbjct: 388 RVNI---TPSG-GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRV 443
Query: 140 VNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYEC 195
V EG +V C A G P P + W LSV + + V L IS + G+YEC
Sbjct: 444 VIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSV-DRRHLVLSSGTLRISGVALHDQGQYEC 502
Query: 196 SALNDVAAPDVRKVKITVN---YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 252
A+N + + V +TV P + S +T V VG L C + P W K
Sbjct: 503 QAVNIIGSQKV-VAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNK- 560
Query: 253 ETRLATGLDGMRIENKGRM-----STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
DG+++ G+ LT +V D G Y CVA N +G+ + S+ L
Sbjct: 561 --------DGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 609
Score = 69.7 bits (169), Expect = 3e-12
Identities = 51/184 (27%), Positives = 84/184 (45%), Gaps = 16/184 (8%)
Query: 129 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVK-EGQGFVSEDEYLEIS 183
P+I + D V G++V C A G P+P + W LS+K + + + +D L I
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQ 305
Query: 184 DIKRDQSGEYECSALNDVAAPDVRKVKITVNY------PPYISKAKNTGVSVGQKGILSC 237
+ + G Y+C A N A +V+ ++T+ Y P ++ + +NT V VG+ L C
Sbjct: 306 NTQETDQGIYQCMAKN--VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 363
Query: 238 EASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
A+ P W + + + I G L NV + D G Y C ATN + +
Sbjct: 364 SATGHPPPRISWTRGDRTPLPVDPRVNITPSG---GLYIQNVVQGDSGEYACSATNNIDS 420
Query: 298 TNAS 301
+A+
Sbjct: 421 VHAT 424
Score = 68.9 bits (167), Expect = 6e-12
Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 12/214 (5%)
Query: 92 SIMIQNVDVYDEGPYTCSVQ-TDNHPKTSRVHLIV---QVPPQIMNISSDITVNEGSSVT 147
++MIQN D+G Y C + KT V L P + + V G SVT
Sbjct: 301 TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVT 360
Query: 148 LLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA 203
L C A G P P ++W R + + ++ L I ++ + SGEY CSA N++ +
Sbjct: 361 LECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 420
Query: 204 PDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGM 263
I P + ++ V GQ CEA P W K ++L+ +
Sbjct: 421 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHL 480
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
+ + TL V+ D G Y C A N +G+
Sbjct: 481 VLSS----GTLRISGVALHDQGQYECQAVNIIGS 510
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 99.8 bits (247), Expect = 3e-21
Identities = 82/278 (29%), Positives = 121/278 (43%), Gaps = 24/278 (8%)
Query: 37 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++ + +S L C + T R+ W +L + ++SI L N + I
Sbjct: 3721 SLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI------LENG----FLHI 3770
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
Q+ V D G Y C R+ L V VPP I +++TV TL C A G
Sbjct: 3771 QSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGI 3830
Query: 156 PEPTVTWRH----LSVKEGQG---FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
P+P++ WR L+V + Q +S + IS D + YEC+ N A D R
Sbjct: 3831 PKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SVDDTATYECTVTNG-AGDDKRT 3888
Query: 209 VKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
V +TV PP I+ + + V+ +++C AS VP W K RL DG RI +
Sbjct: 3889 VDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILS 3948
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
G + L G YTCVA N G+ + +TL+
Sbjct: 3949 SGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLH 3983
Score = 95.1 bits (235), Expect = 8e-20
Identities = 78/277 (28%), Positives = 122/277 (44%), Gaps = 27/277 (9%)
Query: 33 KAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 91
++ +N++V + S +L C + + W D W + + + + +
Sbjct: 2391 RSPENISVVEKNSVSLTCEASGIPLPSITWFK---------DGWPVSLSNSVRILSGGRM 2441
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLL 149
++Q + D G YTC V+ + L V VPP I+ N D+ V E SVTL
Sbjct: 2442 LRLMQTT-MEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLT 2500
Query: 150 CLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
C G P P +TW + L E +S +L+I++++ +G Y C A + A
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA-SSPAGHK 2559
Query: 206 VRKVKITVNYPPYISKAKNTG------VSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
R + V P I+ + G V + L CEA + P A WFK+ T L +
Sbjct: 2560 SRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN 2619
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ +RI GR TL N E + G Y+CVATN+ G
Sbjct: 2620 RN-IRILPGGR--TLQILNAQEDNAGRYSCVATNEAG 2653
Score = 93.6 bits (231), Expect = 2e-19
Identities = 71/281 (25%), Positives = 114/281 (40%), Gaps = 32/281 (11%)
Query: 36 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIIL-----VNTPTQ 90
+NVTV GE A L C I V N W + R + L + T
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDY-------------NLTWQRNDRDVRLAEPARIRTLAN 573
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 150
S+ +++V D G Y C V ++ + V L VQ PP++ + + + GS V+++C
Sbjct: 574 LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMC 633
Query: 151 LAIGRPEPTVTWR---HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR 207
A G P+P + W V + ++ D L I + +G Y C A N
Sbjct: 634 SATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 208 KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG----LDGM 263
+ P + V++G ++ C+ S +P + +WFK + L +D +
Sbjct: 694 STLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPL 753
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ L + D G+YTCVA N+ G ITL
Sbjct: 754 -------LGLLKIQETQDLDAGDYTCVAINEAGRATGKITL 787
Score = 91.3 bits (225), Expect = 1e-18
Identities = 79/276 (28%), Positives = 113/276 (40%), Gaps = 22/276 (7%)
Query: 37 NVTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++TV + TL C D V WL L A PRV IL + +Y + I
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQA-------TPRVRIL--SGGRY-LQI 3679
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
N D+ D YTC T L V VPP I + + S L C+A G
Sbjct: 3680 NNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGV 3739
Query: 156 PEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKI 211
P P +TWR L+ + + E+ +L I +G Y C A N A D R++ +
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATN-AAGTDRRRIDL 3798
Query: 212 TVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT--GLDGMRIENK 268
V+ PP I+ N V V + L+CEA+ +P W K L + R+ +
Sbjct: 3799 QVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSS 3858
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G +L + S D Y C TN G+ ++ L
Sbjct: 3859 G---SLVIISPSVDDTATYECTVTNGAGDDKRTVDL 3891
Score = 91.3 bits (225), Expect = 1e-18
Identities = 78/277 (28%), Positives = 118/277 (42%), Gaps = 24/277 (8%)
Query: 39 TVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 97
TV + A L C D T + W + +L K++ +P ++++N
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEP----------YGELILEN 4228
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 157
V + D G YTC T V L V V P + D+++N+G + L C A G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 158 PTVTWRHLSVKEGQGFVSEDEYLE--ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
P +TW + F S + + E I + ++ SG Y C+A N V V+ +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGF--VKAIGFVYVK 4346
Query: 216 PPYISKA---KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMS 272
P + K N +G IL+CE P QW ++ + RI G S
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS---HRIRQLGNGS 4403
Query: 273 TLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGP 307
+ V+E D G+YTCVATN+ G + S+TL P
Sbjct: 4404 LAIYGTVNE-DAGDYTCVATNEAGVVERSMSLTLQSP 4439
Score = 90.9 bits (224), Expect = 1e-18
Identities = 62/210 (29%), Positives = 95/210 (45%), Gaps = 10/210 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDI--TVNEGSSVTLLCLAIGRPEPT 159
D G YTC + L V PP + + + TV + V L C A G P P
Sbjct: 1892 DAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPV 1951
Query: 160 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
+TW R LS F++ + ++I + +G Y+C A+N A ++ + V+
Sbjct: 1952 ITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YSLQVHV 2010
Query: 216 PPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTL 274
P IS + N V V L CEA +P W K+ + +++ +G+++ + GR+ L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILAL 2070
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
T +S D G YTCVA N G I L
Sbjct: 2071 TSAQIS--DTGRYTCVAVNAAGEKQRDIDL 2098
Score = 90.9 bits (224), Expect = 1e-18
Identities = 77/283 (27%), Positives = 118/283 (41%), Gaps = 23/283 (8%)
Query: 33 KAMDNVTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 91
+++ V VR+G S +L C + V W ++ V IL + +
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-------HVEILADGQMLH 3116
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSS-VTLLC 150
I+ +V D G Y C HL V VPP I ++ V S+ VTL C
Sbjct: 3117 ---IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC 3173
Query: 151 LAIGRPEPTVTW--RHLSVKEGQGF----VSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
A G P PT+ W H ++ +S L+I+ + SG Y C A N +
Sbjct: 3174 DATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGK 3232
Query: 205 DVRKVKITVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
+ +++ PP ++ A+ + V +G+ L C A+ +P QW K+ +A+G +
Sbjct: 3233 AQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASG-E 3291
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
RI STL + D G YTCVATN G + L
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNL 3334
Score = 89.4 bits (220), Expect = 4e-18
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G Y C Q ++ L VQVPP I + + +TL C A G P P +T
Sbjct: 4052 DAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDIT 4111
Query: 162 WRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 214
W K+G+ V L+I+ ++ +G Y C A N VA K+TV+
Sbjct: 4112 WH----KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAAN-VAGSSSTSTKLTVH 4166
Query: 215 YPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMST 273
PP I S + V+ + IL C A +P W K+ LA L E G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE--- 4223
Query: 274 LTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L NV +D G YTCVA N G +++L
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 89.4 bits (220), Expect = 4e-18
Identities = 67/234 (28%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 75 WSIDPRVI---ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI 131
W D R I I + S+ I V D G YTC ++ L V VPP+I
Sbjct: 4112 WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171
Query: 132 MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--GFVSEDEY--LEISDIKR 187
+ TVNE S L C+A G P P + W+ +V G + + Y L + ++
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVL 4231
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVN-YPPYISKAKNTGVSVGQKGILSCEASAVPMAE 246
+ SG Y C A N+ A D V +TV+ P + + ++ G++ LSC+A+ +P+ +
Sbjct: 4232 EDSGFYTCVA-NNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 247 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
W + D + S L VS++D G Y C A N +G A
Sbjct: 4291 LTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 88.2 bits (217), Expect = 1e-17
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD----ITVNEG 143
P ++ I V D G YTC + L V VPP I + S+ + V EG
Sbjct: 3015 PGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREG 3074
Query: 144 SSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 199
+SV+L C + P P +TW R ++ +++ + L I + +G+Y C A+N
Sbjct: 3075 TSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNTGV--SVGQKGILSCEASAVPMAEFQWFKEETRLA 257
VA D + + V PP I + + ++ L+C+A+ +P W K R+
Sbjct: 3135 -VAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIE 3193
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
D + + S L D GNYTC+A+N G
Sbjct: 3194 NS-DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 87.4 bits (215), Expect = 2e-17
Identities = 67/215 (31%), Positives = 101/215 (46%), Gaps = 15/215 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS---DITVNEGSSVTLL 149
+ I + D Y+C +L V + P I N S +I V G S++L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 150 CLAIGRPEPTVTWR---HLSVK-EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
C G P PTVTW H +K +G + E L++ +I +G Y C A+N VA
Sbjct: 2314 CEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVN-VAGMT 2372
Query: 206 VRKVKITVNYPPYI--SKAKNTGVSVGQKG--ILSCEASAVPMAEFQWFKEETRLATGLD 261
+K ++V+ PP I + +SV +K L+CEAS +P+ WFK+ ++ +
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-N 2431
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+RI + GRM L + +D G YTCV N G
Sbjct: 2432 SVRILSGGRM--LRLMQTTMEDAGQYTCVVRNAAG 2464
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/280 (26%), Positives = 113/280 (40%), Gaps = 30/280 (10%)
Query: 40 VRQGESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 97
V +G+ TL CT+ + + W+ S +L + + S+ I+
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-----------YITVRSDGSLHIER 949
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 157
V + D G YTC ++V V P I + ++ EG VTL C A G P+
Sbjct: 950 VQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPK 1009
Query: 158 PTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 213
P+V W +S + D L + ++SGEY C+A N A RKV++TV
Sbjct: 1010 PSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN-TAGYAKRKVQLTV 1068
Query: 214 NYPPYI-------SKAKNTGVSV--GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
P + S+ K +SV G++ L CE ++P W KE ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHT 1128
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G M D G Y CVATN GN ++ L
Sbjct: 1129 FLPSGSMK---ITETRTSDSGMYLCVATNIAGNVTQAVKL 1165
Score = 87.0 bits (214), Expect = 2e-17
Identities = 79/285 (27%), Positives = 114/285 (40%), Gaps = 41/285 (14%)
Query: 35 MDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSI 93
+++V V++ +S TL C + V + W L I +
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL---------- 2535
Query: 94 MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----ITVNEGSSVTL 148
I NV V G YTC + K+ L V V P I + SD +TV S +L
Sbjct: 2536 QITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSL 2595
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKRDQSGEYECSALND 200
+C A P T+TW K+G S L+I + + D +G Y C A N+
Sbjct: 2596 VCEAYSYPPATITW----FKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI---------LSCEASAVPMAEFQWFK 251
A ++ ++ V PP I+K G + K + L CEA A+P A W+K
Sbjct: 2652 -AGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ L + D + I G TL D G YTCVA+N G
Sbjct: 2711 DGQPLKSD-DHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 85.1 bits (209), Expect = 8e-17
Identities = 71/249 (28%), Positives = 110/249 (44%), Gaps = 27/249 (10%)
Query: 80 RVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-- 137
+V+IL P + I V D G YTC + + + + V VPP I +SD
Sbjct: 2823 KVLIL---PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP 2879
Query: 138 --ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKR 187
+TV S + CL+ G P P +W+ K+GQ + +D + L+I + +
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQ----KDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYI--SKAKNTGVSVGQKGILSCEASAVPMA 245
G Y C A N A + + V+ PP + K++N V V L+CE S P
Sbjct: 2936 TDIGRYVCVAEN-TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPP 2994
Query: 246 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SIT 303
+ W K E + + + + GR TL D G YTC+A N+ G + S+T
Sbjct: 2995 DLSWLKNEQPIKLNTNTLIVPG-GR--TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051
Query: 304 LYGPGAVID 312
+Y P ++ D
Sbjct: 3052 VYVPPSIKD 3060
Score = 82.0 bits (201), Expect = 7e-16
Identities = 62/220 (28%), Positives = 97/220 (44%), Gaps = 11/220 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ + + + D G YTC K + L V VPP IM +++V +V LLC +
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQS 2127
Query: 153 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
P PT+TW L K G L+I D + +G Y C A N VA +
Sbjct: 2128 DAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN-VAGKTEKN 2186
Query: 209 VKITVNYPPYISKAKN-TGVSVGQKGILS--CEASAVPMAEFQWFKEETRLATGLDG-MR 264
+ + PP I + T ++V + ++S CE+S +P W K+ + + T G +R
Sbjct: 2187 YNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVR 2246
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
I + GR ++ + D Y+CVA+N G L
Sbjct: 2247 ILSGGRQLQISI--AEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 81.6 bits (200), Expect = 9e-16
Identities = 62/206 (30%), Positives = 94/206 (45%), Gaps = 10/206 (4%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 163
G YTC + V L V PP I S++ V + + L C A G P P +TW+
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQ 4022
Query: 164 ----HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI 219
+++ V L+IS R+ +G Y C A N A + K+K+ V PP I
Sbjct: 4023 KEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNP-AGTALGKIKLNVQVPPVI 4081
Query: 220 S-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFN 278
S K ++V + LSCEA +P + W K+ + + R+ + G +L
Sbjct: 4082 SPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAF 4137
Query: 279 VSEKDYGNYTCVATNKLGNTNASITL 304
V D G+YTC+A N G+++ S L
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/223 (29%), Positives = 99/223 (44%), Gaps = 19/223 (8%)
Query: 95 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLA 152
I + D G Y C + K + + V VPP I + +S V + + L C
Sbjct: 1699 IMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHV 1758
Query: 153 IGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKRDQSGEYECSALNDVAAP 204
G P PT+ W +K+GQ D + L I+ + +G Y C A N A
Sbjct: 1759 TGSPPPTIMW----LKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN-TAGD 1813
Query: 205 DVRKVKITVNYPPYI-SKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDG 262
++ ++TV+ PP I S + V V K + L C A+ +P W K++ + T
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN 1873
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
++I++ GR+ L +D G YTCVATN G T I L+
Sbjct: 1874 LKIQSSGRV--LQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914
Score = 80.9 bits (198), Expect = 2e-15
Identities = 72/276 (26%), Positives = 111/276 (40%), Gaps = 32/276 (11%)
Query: 36 DNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIM 94
+ V+V L C + + W L+ G DP V +L +
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG------DPNVELLDRGQVLH--- 1511
Query: 95 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLA 152
++N D+G Y C+V + + L + +PP I N+++DI+V S + L C
Sbjct: 1512 LKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECET 1571
Query: 153 IGRPEPTVTWRHLSVKEGQG--------FVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
G P P +TW K+GQ ++ + +YL I + S Y C N VA
Sbjct: 1572 RGLPMPAITW----YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVAN-VAGT 1626
Query: 205 DVRKVKITVNYPPYI----SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
+ + V PP I + N V + L C+A+ P W K+ +
Sbjct: 1627 AEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKAN- 1685
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
D +RIE G+ L + E D G Y CVAT+ G
Sbjct: 1686 DNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAG 1719
Score = 80.5 bits (197), Expect = 2e-15
Identities = 73/279 (26%), Positives = 120/279 (43%), Gaps = 27/279 (9%)
Query: 38 VTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
+ V +G+S +L C + V W+ L +D I+ ++
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL----------QLK 2351
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN---ISSDITVNEGSSVTLLCLAI 153
N+ V D G Y C + L V PP I+ +I+V E +SV+L C A
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS 2411
Query: 154 GRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 209
G P P++TW +S+ +S L + + +G+Y C N AA + RK+
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN--AAGEERKI 2469
Query: 210 -KITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 265
++V PP+I + ++ V Q L+CE + P+ E W K+ L + I
Sbjct: 2470 FGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQED-EAHHI 2528
Query: 266 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ GR +T NV G YTC+A++ G+ + S +L
Sbjct: 2529 ISGGRFLQIT--NVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 79.7 bits (195), Expect = 3e-15
Identities = 66/229 (28%), Positives = 96/229 (41%), Gaps = 41/229 (17%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSD----ITVNEGSSVTLLCLAI 153
+ G Y C+ +V L V V P++ +S D I+V G VTL C
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVK 1104
Query: 154 GRPEPTVTW------------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 201
P P +TW RH + G ++I++ + SG Y C A N +
Sbjct: 1105 SLPPPIITWAKETQLISPFSPRHTFLPSGS--------MKITETRTSDSGMYLCVATN-I 1155
Query: 202 AAPDVRKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
A + VK+ V+ PP I + K+ V VGQ+ + C A P+ W K G
Sbjct: 1156 AGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSK-------GG 1208
Query: 261 DGMRIENKGRMS----TLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
M ++ + +S TL+ + D G YTCVATN G ITL+
Sbjct: 1209 STMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Score = 78.6 bits (192), Expect = 8e-15
Identities = 65/219 (29%), Positives = 84/219 (38%), Gaps = 11/219 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS--DITVNEGSSVTLLC 150
+ I V D G YTC + + V VPP I DITV VTL C
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLEC 3643
Query: 151 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
+ P P +TW L +S YL+I++ + Y C A N +A
Sbjct: 3644 KSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN-IAGKTT 3702
Query: 207 RKVKITVNYPPYISKAKNTGVSVGQKG-ILSCEASAVPMAEFQWFKEETRLATGLDGMRI 265
R+ +TVN PP I + V + K +L C A VP W K+ LA I
Sbjct: 3703 REFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI 3762
Query: 266 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G L + D G Y C+ATN G I L
Sbjct: 3763 LENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798
Score = 77.8 bits (190), Expect = 1e-14
Identities = 74/277 (26%), Positives = 103/277 (37%), Gaps = 22/277 (7%)
Query: 38 VTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 97
++V GE TL C + + + T L + PR L + S+ I
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS-----PFSPRHTFLPSG----SMKITE 1139
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 157
D G Y C T V L V VPP+I + V G V + C A G P
Sbjct: 1140 TRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPL 1199
Query: 158 PTVTWR---HLSVKEGQGFVSE-DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 213
P +TW + +G+ VS D L I +G Y C A N +A D ++ + V
Sbjct: 1200 PVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN-IAGTDETEITLHV 1258
Query: 214 NYPPYISKAK---NTGVS---VGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
PP + + NT Q+ C A P +W L G+ I
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILE 1318
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G + L +V+ D G Y CVA N+ G T L
Sbjct: 1319 DGTL--LVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Score = 76.6 bits (187), Expect = 3e-14
Identities = 61/257 (23%), Positives = 108/257 (42%), Gaps = 17/257 (6%)
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
L+ G + +P + IL + ++I +V YD G Y C + + +L V V
Sbjct: 1301 LHNGRELTGREPGISILEDGTL---LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 128 PPQIMNIS--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQG----FVSEDEYLE 181
PP I + ++++V L C G P P + W +V+ + V+ + L+
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILK 1417
Query: 182 ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCE 238
+ + +G Y C A+N +A + I V PP I + V + + L C+
Sbjct: 1418 LFRATPEDAGRYSCKAIN-IAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQ 1476
Query: 239 ASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN- 297
P + WFK+ L G + + ++G++ L N D G Y C +N G
Sbjct: 1477 VKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 298 -TNASITLYGPGAVIDG 313
+ +T+Y P ++ G
Sbjct: 1535 AKDIKLTIYIPPSIKGG 1551
Score = 75.1 bits (183), Expect = 8e-14
Identities = 56/216 (25%), Positives = 92/216 (42%), Gaps = 11/216 (5%)
Query: 95 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 154
I V + DEG Y C + ++ V PP ++ + +++TV G L CL I
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 155 RPEPTVTW----RHLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 209
+ +TW R + + E + LE+ +K + +GEY C ++ V
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSE-GGSSAASV 604
Query: 210 KITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 268
+TV PP ++ KN + G + + C A+ P + W + G R+ +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVND-MFIVGSHRYRMTSD 663
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G TL N + KD G Y C+A+N G + TL
Sbjct: 664 G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696
Score = 74.7 bits (182), Expect = 1e-13
Identities = 62/233 (26%), Positives = 104/233 (44%), Gaps = 18/233 (7%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS--SDITVNEGSSVTLLC 150
+ I++ V D G YTC ++ + VPP I + +TV EG+ ++LLC
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 151 LAIGRPEPTVTWRHLS---VKEGQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 204
+ G P P + W+ + + G V S L+IS ++ + Y C A N VA
Sbjct: 2219 ESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN-VAGT 2277
Query: 205 DVRKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGL 260
++ + V P I+ + + + G+ L CE +P W K+ L
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKA- 2336
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVI 311
G+ I ++G + L +VS D G Y CVA N G T+ ++++ P ++I
Sbjct: 2337 KGVEILDEGHILQLKNIHVS--DTGRYVCVAVNVAGMTDKKYDLSVHAPPSII 2387
Score = 72.8 bits (177), Expect = 4e-13
Identities = 79/325 (24%), Positives = 125/325 (38%), Gaps = 50/325 (15%)
Query: 17 LFIPGVPVRSGDATFPK-AMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKW 75
++IP + + GD P + V ++ + TL C A + S Y
Sbjct: 2663 VYIPPI-INKGDLWGPGLSPKEVKIKVNNTLTLECEA------YAIPSASLSWYKDGQPL 2715
Query: 76 SIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI- 134
D V I N T + I+ + D G YTC + +QVPP +
Sbjct: 2716 KSDDHVNIAANGHT---LQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLW 2772
Query: 135 -------------SSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDE--- 178
+ D+ +N + ++L C P PT+TW K+G S D+
Sbjct: 2773 EIGNMLDTGRNGEAKDVIIN--NPISLYCETNAAPPPTLTW----YKDGHPLTSSDKVLI 2826
Query: 179 -----YLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKA-----KNTGVS 228
L+I K + +G Y C A+N+ A D + + V PP I A + V
Sbjct: 2827 LPGGRVLQIPRAKVEDAGRYTCVAVNE-AGEDSLQYDVRVLVPPIIKGANSDLPEEVTVL 2885
Query: 229 VGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYT 288
V + ++ C +S P W K+ L D + + GR+ L N D G Y
Sbjct: 2886 VNKSALIECLSSGSPAPRNSWQKDGQPLLED-DHHKFLSNGRI--LQILNTQITDIGRYV 2942
Query: 289 CVATNKLGNTNA--SITLYGPGAVI 311
CVA N G+ ++ ++ P +VI
Sbjct: 2943 CVAENTAGSAKKYFNLNVHVPPSVI 2967
Score = 72.0 bits (175), Expect = 7e-13
Identities = 66/232 (28%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 84 LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
L+ P + IQ D G YTC + T ++ L V PP + +D+++ G
Sbjct: 748 LIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIG 807
Query: 144 SSVTLLCLAIGRPEPTVTWRHLS---VKEGQGFVSEDEYLE-----ISDIKRDQSGEYEC 195
S+VTL C G PEPT+ WR L + VS L I ++ G Y C
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 196 SALNDVA-APDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASA-VPMAEFQWFKE 252
A N V +T P I + + V GQ+ L C A P+ E +W K
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKN 927
Query: 253 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L + + + G +L V +D G YTCVA+N G N + ++
Sbjct: 928 SAMLLQN-PYITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSV 975
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 25/220 (11%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI--SSDITVNEGSSVTLLC 150
I I V D YTC +L V PP + N + +ITV +GSS ++ C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 151 LAIGRPEPTVTW----------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALND 200
+ G P P++ W HL+V G V L++ + + SG+Y C A N+
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHLTVST-HGMV-----LQLLKAETEDSGKYTCIASNE 3511
Query: 201 VAAPDVRKVKITVNYPPYIS---KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
A + + V PP+I+ + + V V L+C AS +P + W K+ L
Sbjct: 3512 -AGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
+++ G L +D G YTC+A++ G+
Sbjct: 3571 ---QTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607
Score = 63.2 bits (152), Expect = 3e-10
Identities = 60/237 (25%), Positives = 93/237 (39%), Gaps = 31/237 (13%)
Query: 92 SIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 147
++ I+N D G Y C S TD T R P++M + S++ V G
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI----EAPKLMVVQSELLVALGDITV 720
Query: 148 LLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEISDIKRDQ---SGEYECSALNDVAA 203
+ C G P P V W ++ F+ D L + I+ Q +G+Y C A+N+ A
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINE-AG 779
Query: 204 PDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
K+ + V PP +I + + + +G L C P +W + LD
Sbjct: 780 RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRR--------LDN 831
Query: 263 MRIENKG---------RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAV 310
M I ++ R L N+ D G Y C A N+ G + T+ G V
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLV 888
Score = 63.2 bits (152), Expect = 3e-10
Identities = 62/274 (22%), Positives = 119/274 (43%), Gaps = 23/274 (8%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
TF + +V++ +GE L C + ++ W + I+ A D VN
Sbjct: 4261 TFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS----------VNGH 4310
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM-NISSDITVNEGSSVT 147
++ ++I+ V D G Y C+ + + + V+ PP + S+ G +
Sbjct: 4311 SE--LVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAI 4368
Query: 148 LLCLAIGRPEPTVTWRHLSVK-EGQGFVSE--DEYLEISDIKRDQSGEYECSALNDVAAP 204
L C G P PT+ W V E + + + L I + +G+Y C A N+
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428
Query: 205 DVRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGM 263
+ R + +T+ PP I+ + T ++ G K IL+C+A+ P W ++ ++ D +
Sbjct: 4429 E-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD-DRV 4486
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
+ + ++L + ++D + CVA N +G+
Sbjct: 4487 NVLSN---NSLYIADAQKEDTSEFECVARNLMGS 4517
Score = 57.8 bits (138), Expect = 1e-08
Identities = 51/203 (25%), Positives = 80/203 (39%), Gaps = 18/203 (8%)
Query: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
V F +++ PV GD +P N G +A L C + T NR
Sbjct: 4334 VGFVKAIGFVYVKEPPVFKGD--YPS---NWIEPLGGNAILNCEVKGDPTPTIQWNRK-- 4386
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
+D + + S+ I D G YTC + + L +Q
Sbjct: 4387 --------GVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR---HLSVKEGQGFVSEDEYLEISD 184
PP I + +N G + L C A G P+PT+TW H + + V + L I+D
Sbjct: 4439 PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIAD 4498
Query: 185 IKRDQSGEYECSALNDVAAPDVR 207
+++ + E+EC A N + + VR
Sbjct: 4499 AQKEDTSEFECVARNLMGSVLVR 4521
Score = 57.0 bits (136), Expect = 2e-08
Identities = 70/296 (23%), Positives = 113/296 (38%), Gaps = 30/296 (10%)
Query: 22 VPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPR 80
VP A P +V+V GE+ L C + T + WL + +G + R
Sbjct: 3243 VPPSVAGAEIPS---DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE-----R 3294
Query: 81 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVPPQIMNISSD-- 137
+ + N T + I D G YTC V T+ + R+ +L V V P I +
Sbjct: 3295 IRVSANGST---LNIYGALTSDTGKYTC-VATNPAGEEDRIFNLNVYVTPTIRGNKDEAE 3350
Query: 138 -ITVNEGSSVTLLCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGE 192
+ +S+ + C A G P P + W L + ++ + + I +
Sbjct: 3351 KLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAV 3410
Query: 193 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQW 249
Y C A N A D + + V PP + + T V G ++C P W
Sbjct: 3411 YTCVASNR-AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAW 3469
Query: 250 FKEETRLATGLDG-MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++ L GLD + + G + L +D G YTC+A+N+ G + L
Sbjct: 3470 LRDGQPL--GLDAHLTVSTHGMV--LQLLKAETEDSGKYTCIASNEAGEVSKHFIL 3521
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 37 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 408 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 457
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 458 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 517
Query: 156 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 518 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 576
Query: 213 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 577 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 630
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L E+D G YTC A N+LG+ +A I L
Sbjct: 631 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 663
Score = 82.4 bits (202), Expect = 5e-16
Identities = 79/285 (27%), Positives = 112/285 (39%), Gaps = 34/285 (11%)
Query: 37 NVTVRQGESATLRCTIDDRVTRVAWLNRST------ILYAGNDKWSIDPRVIILVNTPTQ 90
+VTV G SA L C R R L AG S P +L
Sbjct: 677 DVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVL------ 730
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV--QVPPQIMNISSDITVNEGSSVTL 148
++V D+ PY C + + LIV PPQI + + + V EG V+L
Sbjct: 731 ---FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSL 787
Query: 149 LCLAI-GRPEPTVTWRHLSVKEGQGF-------VSEDEYLEISDIKRDQSGEYECSALND 200
C+ + GRP P W +K+G+ + D L + ++ +G Y C A N
Sbjct: 788 PCIVLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATN- 842
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVS-VGQKGILSCEASAVPMAEFQWFKEETRLATG 259
A R V++ V PP I ++ G L C AS VP W KE L +
Sbjct: 843 TAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSR 902
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +G TL S +D G Y C ATN +G ++ + L
Sbjct: 903 GPHYNVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 944
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 373 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 432
Query: 162 ----WRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
WR L G+ D LEIS I G Y+C A N V + V P
Sbjct: 433 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 491
Query: 218 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 492 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 547
Query: 277 FNVSEKDYGNYTCVATNKLGNTNASITLY 305
V+ +D GNY+C ATN++G ++TLY
Sbjct: 548 QGVAPEDAGNYSCQATNEVGTDQETVTLY 576
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 19/217 (8%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G YTC + ++ + L V PQ+ + D+TV G S L C A GRP PTVT
Sbjct: 642 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 701
Query: 162 WRH-----LSVKEGQGFVS-----EDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVK 210
WR L ++ G G S + L + + Y C A N ++
Sbjct: 702 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 761
Query: 211 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATG-LDGMRIEN 267
+T + PP I S A V GQ L C A P+ E W K+ L G +R +
Sbjct: 762 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD- 820
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+L ++ G Y+CVATN G+ + + L
Sbjct: 821 ----GSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL 853
Score = 75.5 bits (184), Expect = 6e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 16/208 (7%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW- 162
G Y+C + V L+VQVPP+I ++ NEG +L C+A G P PT+TW
Sbjct: 834 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 893
Query: 163 ---RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP-- 217
L+ + VS++ L I+ +G Y C+A N V ++++++VN P
Sbjct: 894 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSS-QEMRLSVNTKPRI 952
Query: 218 YISKAKNTGV------SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
+++ ++N V G++ L CEA P W K+ + + + G
Sbjct: 953 HMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG-- 1010
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTN 299
+L V D G+Y C A+N G+ +
Sbjct: 1011 -SLRLAQVQVGDSGHYECTASNPAGSAS 1037
Score = 72.4 bits (176), Expect = 5e-13
Identities = 55/233 (23%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 85 VNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGS 144
++ Q +++IQ V D G Y+C + V L PP + +++ + V G
Sbjct: 537 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE 596
Query: 145 SVTLLCLAIGRPEPTVTW-----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 199
L+C A G P P V W + EG S L I + +G Y C A+N
Sbjct: 597 EAVLVCEASGVPPPRVIWYRGGLEMILAPEG----SSSGKLRIPAAQERDAGTYTCRAVN 652
Query: 200 DVAAPDVRKVKITVNYPPYISK-AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR--- 255
++ ++++ V + P +++ ++ V +G+ +L+C A+ P W + + +
Sbjct: 653 ELGDASA-EIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLG 711
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 308
L G + L F +V+ +D Y C A N G A L G
Sbjct: 712 LRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 764
Score = 52.8 bits (125), Expect = 4e-07
Identities = 45/191 (23%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 32 PKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 90
P A ++T +G A+L C + W + L + +++ +L+ P+
Sbjct: 863 PTATHHIT-NEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPS- 920
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-------MNISSDITVNEG 143
D G Y C+ + + L V P+I N+ +T G
Sbjct: 921 ---------AQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAG 971
Query: 144 SSVTLLCLAIGRPEPTVTWRHLS-----VKEGQGFVSEDEYLEISDIKRDQSGEYECSAL 198
VTL C A G P P VTW S + G + L ++ ++ SG YEC+A
Sbjct: 972 EEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS-LRLAQVQVGDSGHYECTAS 1030
Query: 199 NDVAAPDVRKV 209
N + R V
Sbjct: 1031 NPAGSASHRYV 1041
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 165 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 216
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 341 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 400
Query: 217 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 274
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 401 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 455
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ D G Y CVA+N G T AS+ L
Sbjct: 456 EISGIIPTDGGRYQCVASNANGVTRASVWL 485
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 37 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 574
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 575 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 634
Query: 156 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 635 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 693
Query: 213 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 747
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L E+D G YTC A N+LG+ +A I L
Sbjct: 748 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 780
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 88 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 1841 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 1900
Query: 144 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 199
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 1901 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 1960
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 1961 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 2019
Query: 258 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 2020 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 2065
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/247 (28%), Positives = 114/247 (46%), Gaps = 22/247 (8%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ + V V D G Y C+ + R L VQVPPQ+ + V G ++ L C+
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCV 1142
Query: 152 AIGRPEPTVTW-RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
A G PEP ++W + V +G+G + + I+ +G Y C A N A D +V+
Sbjct: 1143 AEGNPEPQLSWSKDGVVLQGRG---PQGSVHFAAIRTSDAGRYRCEASNS-AGVDAWEVE 1198
Query: 211 ITVNYPPYISKAKNTGV---SVGQKGILSCEASAVPMAEFQWFK-EETRLATGLDGMRIE 266
+ V PP+ + +G+ G+ L C A P + W K + G G+ +
Sbjct: 1199 LRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVL 1258
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGPGAV--------IDGVNS 316
+G +L +VS D G+Y C ATN++G+T+ A + +Y P ++ + G+
Sbjct: 1259 EEG---SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAG 1315
Query: 317 ASRALAC 323
S L C
Sbjct: 1316 QSLTLEC 1322
Score = 90.5 bits (223), Expect = 2e-18
Identities = 79/293 (26%), Positives = 121/293 (41%), Gaps = 27/293 (9%)
Query: 23 PVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGNDKWSIDPRV 81
PV GD + ++ VTV + +L+C + + V ++WL +S PR+
Sbjct: 2842 PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL-------PFSPSPRL 2892
Query: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-ITV 140
+L + + + +V D Y C + L VQVPP+I + + +T
Sbjct: 2893 QVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 2949
Query: 141 NEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
SSV+L C P P VTW + LS+ E + L++ + SG Y C
Sbjct: 2950 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE 3009
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAVPMAEFQWFK 251
ALN A D + V+++V PP +A V VG K +LSCE A+P W+K
Sbjct: 3010 ALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK 3068
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ L + R L D G Y+C +N G + TL
Sbjct: 3069 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 3118
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 153 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 4120
Query: 209 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 4121 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 4175
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+ STL VS +D G Y C A N++G T A
Sbjct: 4176 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 4208
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 3889
Query: 162 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 3890 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 3948
Query: 218 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 3949 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 4004
Query: 277 FNVSEKDYGNYTCVATNKLGN 297
+ S +D GNY C+A N G+
Sbjct: 4005 AHASPEDAGNYLCIAKNSAGS 4025
Score = 82.4 bits (202), Expect = 5e-16
Identities = 79/285 (27%), Positives = 112/285 (39%), Gaps = 34/285 (11%)
Query: 37 NVTVRQGESATLRCTIDDRVTRVAWLNRST------ILYAGNDKWSIDPRVIILVNTPTQ 90
+VTV G SA L C R R L AG S P +L
Sbjct: 794 DVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVL------ 847
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV--QVPPQIMNISSDITVNEGSSVTL 148
++V D+ PY C + + LIV PPQI + + + V EG V+L
Sbjct: 848 ---FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSL 904
Query: 149 LCLAI-GRPEPTVTWRHLSVKEGQGF-------VSEDEYLEISDIKRDQSGEYECSALND 200
C+ + GRP P W +K+G+ + D L + ++ +G Y C A N
Sbjct: 905 PCIVLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATN- 959
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVS-VGQKGILSCEASAVPMAEFQWFKEETRLATG 259
A R V++ V PP I ++ G L C AS VP W KE L +
Sbjct: 960 TAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSR 1019
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +G TL S +D G Y C ATN +G ++ + L
Sbjct: 1020 GPHYNVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 1061
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 36 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 92
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 3040 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 3086
Query: 93 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 149
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 3145
Query: 150 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 3146 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 3203
Query: 206 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 3204 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 3262
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G + +L + D G YTCVA N G
Sbjct: 3263 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 490 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 549
Query: 162 ----WRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
WR L G+ D LEIS I G Y+C A N V + V P
Sbjct: 550 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 608
Query: 218 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 609 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 664
Query: 277 FNVSEKDYGNYTCVATNKLGNTNASITLY 305
V+ +D GNY+C ATN++G ++TLY
Sbjct: 665 QGVAPEDAGNYSCQATNEVGTDQETVTLY 693
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 103 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 159
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 2230 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 2289
Query: 160 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 2290 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 2348
Query: 216 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 2349 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 2407
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 310
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 2408 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 2446
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 19/217 (8%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G YTC + ++ + L V PQ+ + D+TV G S L C A GRP PTVT
Sbjct: 759 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 818
Query: 162 WRH-----LSVKEGQGFVS-----EDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVK 210
WR L ++ G G S + L + + Y C A N ++
Sbjct: 819 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 878
Query: 211 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATG-LDGMRIEN 267
+T + PP I S A V GQ L C A P+ E W K+ L G +R +
Sbjct: 879 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD- 937
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+L ++ G Y+CVATN G+ + + L
Sbjct: 938 ----GSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL 970
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 158
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 1567 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 1626
Query: 159 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 214
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 1627 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 1685
Query: 215 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 1686 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 1742
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 314
+TL +V G + C ATN+ G A + + G GV
Sbjct: 1743 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 1785
Score = 76.3 bits (186), Expect = 4e-14
Identities = 79/312 (25%), Positives = 127/312 (40%), Gaps = 34/312 (10%)
Query: 37 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 2079 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 2129
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 155
DV+D G YTC +L V V P + S +TV EG +L C G
Sbjct: 2130 RADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGV 2189
Query: 156 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 205
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 2190 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 2244
Query: 206 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 261
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 2245 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 2303
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 319
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 2304 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 2361
Query: 320 ALACLWLSGTLL 331
A L TLL
Sbjct: 2362 ITAALHSPLTLL 2373
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 148
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 3367 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 3426
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 204
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 3427 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 3481
Query: 205 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 3482 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 3537
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+EN R + + + +D G YTC+A + G
Sbjct: 3538 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 3566
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 163
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 3982
Query: 164 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 220
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 3983 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 4041
Query: 221 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 279
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 4042 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 4098
Query: 280 SEKDYGNYTCVATNKLGNTNASITL 304
+D G YTC A N +G + L
Sbjct: 4099 EGQDAGTYTCTAENAVGRARRRVHL 4123
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 140
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 2592 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 2651
Query: 141 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 192
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 2652 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 2707
Query: 193 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 231
Y C A N VA D + + + PP K + +
Sbjct: 2708 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766
Query: 232 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 2767 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 2823
Query: 292 TNKLG 296
+N++G
Sbjct: 2824 SNEVG 2828
Score = 72.8 bits (177), Expect = 4e-13
Identities = 66/251 (26%), Positives = 97/251 (38%), Gaps = 68/251 (27%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 163
G Y+C + V L+VQVPP+I ++ NEG +L C+A G P PT+TW
Sbjct: 951 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 1010
Query: 164 -----------HLSV-KEGQ----------------------GFVSE------------- 176
H +V KEG GF S+
Sbjct: 1011 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSK 1070
Query: 177 ---DEY-------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT- 225
+EY L ++ ++ SG YEC+A N + R V + V PP +
Sbjct: 1071 YVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYV-LGVQVPPQVQPGPRVL 1129
Query: 226 GVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYG 285
V VG+ L+C A P + W K DG+ ++ +G ++ F + D G
Sbjct: 1130 KVLVGEALDLNCVAEGNPEPQLSWSK---------DGVVLQGRGPQGSVHFAAIRTSDAG 1180
Query: 286 NYTCVATNKLG 296
Y C A+N G
Sbjct: 1181 RYRCEASNSAG 1191
Score = 72.4 bits (176), Expect = 5e-13
Identities = 55/233 (23%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 85 VNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGS 144
++ Q +++IQ V D G Y+C + V L PP + +++ + V G
Sbjct: 654 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE 713
Query: 145 SVTLLCLAIGRPEPTVTW-----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 199
L+C A G P P V W + EG S L I + +G Y C A+N
Sbjct: 714 EAVLVCEASGVPPPRVIWYRGGLEMILAPEG----SSSGKLRIPAAQERDAGTYTCRAVN 769
Query: 200 DVAAPDVRKVKITVNYPPYISK-AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR--- 255
++ ++++ V + P +++ ++ V +G+ +L+C A+ P W + + +
Sbjct: 770 ELGDASA-EIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLG 828
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 308
L G + L F +V+ +D Y C A N G A L G
Sbjct: 829 LRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 881
Score = 72.4 bits (176), Expect = 5e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 159
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 2417 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 2476
Query: 160 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 2477 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 2535
Query: 216 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 261
P I S + V+V L CEA A P W K+ +L G
Sbjct: 2536 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 2595
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G++I N ++D G YTCV TN+LG
Sbjct: 2596 GLQI-----------LNAQKEDAGQYTCVVTNELG 2619
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 75 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 134
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 3440 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 3499
Query: 135 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 191
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 3500 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 3555
Query: 192 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 247
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 3556 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 3613
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 304
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 3614 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 3670
Query: 305 ------YGPGAVIDGVNSAS 318
GP AV VN +
Sbjct: 3671 TVPTIRSGPPAVNVSVNQTA 3690
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 148
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 2806 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 2865
Query: 149 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 2866 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925
Query: 205 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 2926 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 2984
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ TL D G YTC A N G + L
Sbjct: 2985 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 3023
Score = 69.7 bits (169), Expect = 3e-12
Identities = 59/229 (25%), Positives = 87/229 (37%), Gaps = 27/229 (11%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN--EGSSVTLL 149
S+ + +V D G Y C + + R L+V VPP I V+ G S+TL
Sbjct: 1262 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 1321
Query: 150 CLAIGRPEPTVTWRH-------------------LSVKEGQGFVSEDEYLEISDIKRDQS 190
C A G P P + W G + E + L I+ S
Sbjct: 1322 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDS 1381
Query: 191 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEF 247
G Y C A N R + V PP + A +G G L C S VP +
Sbjct: 1382 GLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQV 1440
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+W K+ + G ++++ G++ +T +V D G Y CVA + G
Sbjct: 1441 EWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG--DEGRYQCVAFSPAG 1487
Score = 68.6 bits (166), Expect = 8e-12
Identities = 79/308 (25%), Positives = 124/308 (40%), Gaps = 30/308 (9%)
Query: 24 VRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVI 82
+RSG P A+ NV+V Q +A L C D V+W D+ +DPR
Sbjct: 3675 IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVPLDPRSP 3718
Query: 83 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE 142
P + S+ IQ V D G Y C L V PP I S++T+
Sbjct: 3719 RFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 3777
Query: 143 GSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
+ L C A G P+P V W +++G + L ++ S ++EC
Sbjct: 3778 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 3837
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQWFKEETR 255
N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W K +
Sbjct: 3838 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 3896
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPGAVIDGV 314
L G R+ G + + G YTC A N G + + L V+ +
Sbjct: 3897 LGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQASPVVKPL 3953
Query: 315 NSASRALA 322
S RA+A
Sbjct: 3954 PSVVRAVA 3961
Score = 67.8 bits (164), Expect = 1e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 2044 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 2103
Query: 162 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 2104 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGHSEKHYNLNVWVAP 2162
Query: 218 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 274
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 2163 VFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 2222
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++++ G YTC +N +GN++ + L
Sbjct: 2223 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 2250
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 150
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 1524
Query: 151 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 1525 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 1583
Query: 207 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 1584 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 1643
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+E G S L + E G Y+CVA++ G
Sbjct: 1644 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 1674
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 40 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 3280
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 154
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 3281 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 3339
Query: 155 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 3340 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 3398
Query: 211 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 266
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 3399 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 3453
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +L V D G Y+CVA ++ G L
Sbjct: 3454 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 3488
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 3696
Query: 153 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 3697 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 3755
Query: 209 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 263
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 3756 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 3815
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 312
N L +D + CV +N++G + +T++ P + D
Sbjct: 3816 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 3861
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 159
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 4191 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 4249
Query: 160 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 4250 IHW----IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 4305
Query: 213 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 266
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 4361
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+L NV D G Y CVA N LG+ A
Sbjct: 4362 ------SLWLENVETGDAGTYDCVAHNLLGSATA 4389
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ I + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 4272 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 4331
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 204
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 4332 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 4387
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 245
R + V P S TGV G+K G+ + S + A
Sbjct: 4388 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 4428
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 165 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 216
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 458 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 517
Query: 217 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 274
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 518 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 572
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ D G Y CVA+N G T AS+ L
Sbjct: 573 EISGIIPTDGGRYQCVASNANGVTRASVWL 602
Score = 35.8 bits (81), Expect = 0.056
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 12/95 (12%)
Query: 37 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++TVR G+ LRC T + WL L A + T S+ +
Sbjct: 4317 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-----------RLRTLPDGSLWL 4365
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ 130
+NV+ D G Y C T+R L+V+ PQ
Sbjct: 4366 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 37 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 524 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 573
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 574 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 633
Query: 156 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 634 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 692
Query: 213 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 693 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 746
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L E+D G YTC A N+LG+ +A I L
Sbjct: 747 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 779
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 489 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 548
Query: 162 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W R L G+ D LEIS I G Y+C A N V + V P
Sbjct: 549 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 607
Query: 218 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 608 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 663
Query: 277 FNVSEKDYGNYTCVATNKLGNTNASITLY 305
V+ +D GNY+C ATN++G ++TLY
Sbjct: 664 QGVAPEDAGNYSCQATNEVGTDQETVTLY 692
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 165 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 216
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 457 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 516
Query: 217 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 274
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 517 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 571
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ D G Y CVA+N G T AS+ L
Sbjct: 572 EISGIIPTDGGRYQCVASNANGVTRASVWL 601
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 97.1 bits (240), Expect = 2e-20
Identities = 75/277 (27%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 37 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++ V GESA C + + R+ W + + G + + + NTP + I
Sbjct: 6279 SIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY-----TITCVGNTP---HLRI 6330
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ-IMNISSDITVNEGSSVTLLCLAIG 154
V D G YTC D L V+ PP+ + + + +G S+ L C G
Sbjct: 6331 LKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISG 6390
Query: 155 RPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
PE V+W H S K F++ L I++ + SG+Y C A N V
Sbjct: 6391 SPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASC-S 6449
Query: 209 VKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
+TV PP + K G G IL CE S P E W K+ ++ +I +
Sbjct: 6450 TALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNS-KKFKITS 6508
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
K ++L N+ D G Y C ATN++G+ S ++
Sbjct: 6509 KHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 93.6 bits (231), Expect = 2e-19
Identities = 71/283 (25%), Positives = 117/283 (41%), Gaps = 21/283 (7%)
Query: 31 FPKAMDNVTVRQGESATLRCTID-DRVTRVAWLNRSTILYAGND-KWSIDPRVIILVNTP 88
F K ++ V + L C +D DR V W L G D K + ++ L
Sbjct: 3646 FIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE--- 3702
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ-IMNISSDITVNEGSSVT 147
I + D G Y C+ + + + V+ PP + + + G S
Sbjct: 3703 ------IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESAR 3756
Query: 148 LLCLAIGRPEPTVTWRHLSVKEGQG------FVSEDEYLEISDIKRDQSGEYECSALNDV 201
L C G P VTW + + + FV+ + L+I+D+K + SG Y C A+NDV
Sbjct: 3757 LHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDV 3816
Query: 202 AAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
+ D +I + PP +I + + G +L CE S E WFK++ ++ +
Sbjct: 3817 GS-DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSS- 3874
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT 303
R+ ++ + L F+ + D G Y CV N++G T
Sbjct: 3875 KKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 3917
Score = 90.9 bits (224), Expect = 1e-18
Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 18/284 (6%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 89
F ++++TV GE A L+ +I+ + V WL + ++ + R+ + N T
Sbjct: 5612 FVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE----NIRITFVENVAT 5667
Query: 90 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLL 149
+ + + G Y C ++ D + + L+V P I+ + +TV G + TL
Sbjct: 5668 ---LQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLE 5724
Query: 150 CLAIGRPEPTVTWRH------LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-- 201
C G PE +V W S K F ++ L I ++R +G Y N+V
Sbjct: 5725 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGK 5784
Query: 202 -AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
+ V V P + + KNTG +G IL C+ + WF E+T++ +G
Sbjct: 5785 SSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGA 5844
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ + TL ++ D GNYTCVA N G+ L
Sbjct: 5845 K-YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 5887
Score = 85.9 bits (211), Expect = 5e-17
Identities = 71/283 (25%), Positives = 119/283 (42%), Gaps = 18/283 (6%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
+F + D+V V G S T I +V W S L G + I L +
Sbjct: 6835 SFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG------ESCNISLEDFV 6888
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
T+ + V + G Y+C V D + HL V+ P + +D +V GS + L
Sbjct: 6889 TELELF--EVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVL 6946
Query: 149 LCLAIGRPEPTVTW---RHLSVKEGQGFVSEDE---YLEISDIKRDQSGEYECSALNDVA 202
G P +V+W +L + + ++ E LEI + + +Y C N+ A
Sbjct: 6947 EATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENE-A 7005
Query: 203 APDVRKVKITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
D+ + ++V PPY I ++ +G+ L C+ P W+KE T+L +
Sbjct: 7006 GQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSA-P 7064
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+++ K +++L V D G Y+C A N +G +S L
Sbjct: 7065 AYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 7107
Score = 85.5 bits (210), Expect = 6e-17
Identities = 56/215 (26%), Positives = 96/215 (44%), Gaps = 9/215 (4%)
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 156
+VD G YTC V + + HL ++ P + + +D ++ +G + L G P
Sbjct: 7836 DVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTP 7895
Query: 157 EPTVTWRH--LSVKEGQ----GFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
+VTW+ ++V Q + LEI + +G+Y C + + + D +
Sbjct: 7896 PISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNC-YIENASGKDSCSAQ 7954
Query: 211 ITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 269
I + PPY + + + VSVG L C+ + P W+K +T+L ++ +
Sbjct: 7955 ILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRP-TTTYKMHFRN 8013
Query: 270 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++TL F V D G Y C A N +G +AS L
Sbjct: 8014 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFL 8048
Score = 84.0 bits (206), Expect = 2e-16
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 156
N+D+ G YTC V + + L V+ P + SD +V G S+ L G
Sbjct: 5954 NIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTL 6013
Query: 157 EPTVTWR----HLSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
+VTW+ +++ E V+ ++ LEI + + +G+Y C N+ A DV
Sbjct: 6014 PISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENE-AGRDVCGAL 6072
Query: 211 ITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 269
++ PPY +++ + +VG L C+ + P W+K +T+L + R
Sbjct: 6073 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPE-YRTYFTN 6131
Query: 270 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
++TL F V+ D G YTC A N +G ++
Sbjct: 6132 NVATLVFNKVNINDSGEYTCKAENSIGTASS 6162
Score = 81.6 bits (200), Expect = 9e-16
Identities = 78/307 (25%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 29 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 87
AT + +++ V G++ TL CT+ W L + N K+ I N
Sbjct: 7586 ATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDN-KYKIS-----FFNK 7639
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGS 144
+ I+ NV D G Y+ VQ + L V VPP + GS
Sbjct: 7640 VSGLKII--NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGS 7697
Query: 145 SVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYE 194
SV + C G P +V+W H EG S +Y L ++ ++ SG+Y
Sbjct: 7698 SVVMECKVYGSPPISVSWFH----EGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 7753
Query: 195 CSALNDVAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 253
C A N +A D +TV PP ++ K V G + P WFK
Sbjct: 7754 CIATN-MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS 7812
Query: 254 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY--GPGAVI 311
+ L G D + + ++ L F+V G YTC+ +N+ G + + LY P +
Sbjct: 7813 SELVPG-DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFV 7871
Query: 312 DGVNSAS 318
+N S
Sbjct: 7872 KRLNDYS 7878
Score = 80.1 bits (196), Expect = 3e-15
Identities = 71/286 (24%), Positives = 118/286 (41%), Gaps = 27/286 (9%)
Query: 30 TFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
+F K ++N T SAT + T+ + WL IL ++ + I V++
Sbjct: 5049 SFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVY------ISFVDSV 5102
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
++ I++VD G YTC + ++ + L+VQ P QI+ + + V E +TL
Sbjct: 5103 A--TLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTL 5160
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSAL 198
C+ G PE V W +K+G+ V + I + + SG+Y
Sbjct: 5161 ECVVAGTPELKVKW----LKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 5216
Query: 199 NDVAAP--DVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR 255
ND + D + N PP + K +G + C+ S QWFK+
Sbjct: 5217 NDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKE 5276
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 301
++T R+ R +L N+ +D NYTC +N G+ S
Sbjct: 5277 ISTSAK-YRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACS 5321
Score = 79.7 bits (195), Expect = 3e-15
Identities = 61/236 (25%), Positives = 97/236 (41%), Gaps = 10/236 (4%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLLC 150
S+ + V D G YTC V +L V+ P + + + +G + L C
Sbjct: 4262 SLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLAC 4321
Query: 151 LAIGRPEPTVTW----RHL--SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
G P +TW R + S K FV L ++D+ + SGEY C A N+ +
Sbjct: 4322 KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSD 4381
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ I P + + K V +L E + P E WFK+ T L +G +
Sbjct: 4382 HCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK-YK 4440
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAVIDGVNSAS 318
+ + +L D G Y C TN++G++ +A +TL P + I + S S
Sbjct: 4441 TFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTS 4496
Score = 79.3 bits (194), Expect = 4e-15
Identities = 66/289 (22%), Positives = 115/289 (39%), Gaps = 28/289 (9%)
Query: 31 FPKAMDNVTVRQGESATLRCTID--DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
F K + +++ G+ L+ TI+ + ++ V + ++ I+ ++ W + +
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW--------ISYSE 7545
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
++ V+ + G YTC ++ D + L V P I+ I V G + TL
Sbjct: 7546 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTL 7605
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSAL 198
C G PE + W K+G+ S+++Y L+I ++ SG Y
Sbjct: 7606 ECTVAGTPELSTKW----FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 7661
Query: 199 NDVAAPDVR---KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR 255
N V +V P + K K T G ++ C+ P WF E
Sbjct: 7662 NPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNE 7721
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+++G + LT + E D G+YTC+ATN G+ S L
Sbjct: 7722 ISSGRK-YQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPL 7769
Score = 77.8 bits (190), Expect = 1e-14
Identities = 76/289 (26%), Positives = 123/289 (42%), Gaps = 33/289 (11%)
Query: 30 TFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYA-GNDKWSIDPRVIILVNT 87
TF K +D++ G++ TL+ + V W+ ++ G K S V +L+
Sbjct: 3925 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLI-- 3982
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 147
I +V + G YTC + + +TS LIV+ P +I+ + I V G T
Sbjct: 3983 -------IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPAT 4035
Query: 148 LLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSA 197
L G PE W K+G+ V+ +Y L+ + SG+Y
Sbjct: 4036 LEYTVAGTPELKPKW----YKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 4091
Query: 198 LNDVAAPDVRKVKITV---NYPPYISK-AKNTGVSVGQKGILSCE-ASAVPMAEFQWFKE 252
N+V + + TV + P+ +K +N V L C+ A ++PM WFK+
Sbjct: 4092 SNEVGSSSC-ETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPM-RVSWFKD 4149
Query: 253 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 301
+A D RI ++L V D GN+TC ATN +G+ ++S
Sbjct: 4150 GKEIAAS-DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 4197
Score = 77.0 bits (188), Expect = 2e-14
Identities = 61/243 (25%), Positives = 98/243 (40%), Gaps = 12/243 (4%)
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV-NEGSSVT 147
T S+ + D G Y C + D TS+ L V+ PPQ + S + V G S T
Sbjct: 4821 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTT 4880
Query: 148 LLCLAIGRPEPTVTW----RHLSV--KEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 201
C G P+ V+W ++ K G F+ +IS + + SG Y C A ND
Sbjct: 4881 FECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDA 4940
Query: 202 AAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
+++ V PP +I + K V L CE + P E W K + +
Sbjct: 4941 GTASC-SIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSS- 4998
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS--ITLYGPGAVIDGVNSAS 318
+ ++ + L D G Y C+ +N+ G+ + S + L P + I + + +
Sbjct: 4999 KKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTT 5058
Query: 319 RAL 321
L
Sbjct: 5059 TVL 5061
Score = 76.6 bits (187), Expect = 3e-14
Identities = 60/227 (26%), Positives = 94/227 (41%), Gaps = 10/227 (4%)
Query: 95 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 154
+ N+ V D G YTC +S L V+ PP I +G+ V L C G
Sbjct: 7365 MHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQG 7424
Query: 155 RPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQS--GEYECSALNDVAAPDVRK 208
P V+W R L + +SE+ I + D + GEY+C A NDV + D
Sbjct: 7425 TPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCV 7483
Query: 209 VKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
I + PP ++ K + VG++ L WFK++ + D + I
Sbjct: 7484 GSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 7543
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGPGAVID 312
++TL F V + G YTC N G A++++ P +++
Sbjct: 7544 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVE 7590
Score = 75.5 bits (184), Expect = 6e-14
Identities = 72/288 (25%), Positives = 114/288 (39%), Gaps = 21/288 (7%)
Query: 29 ATFPKAMDNVTVRQGESATLRCTIDDRVTRVA-WLNRSTILYAGNDKWSIDPRVIILVNT 87
AT + ++ V QG+ ATL+ A W L G+ K+ I T
Sbjct: 4579 ATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS-KYKISV-------T 4630
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGS 144
T + I + + D G YT VQ D + + + V +PP + +GS
Sbjct: 4631 DTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGS 4690
Query: 145 SVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSAL 198
+ L C+ G ++ W + +S E F D +LEIS ++ SG Y CSA
Sbjct: 4691 FIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSAT 4750
Query: 199 NDVAAPDVRKVKITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
N A + +TV PPY + K ++ V+ + L +WFK+ L
Sbjct: 4751 NK-AGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH 4809
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
+G + ++L F D G Y C +N +G + TL+
Sbjct: 4810 SGA-ARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 4856
Score = 75.1 bits (183), Expect = 8e-14
Identities = 70/286 (24%), Positives = 113/286 (39%), Gaps = 25/286 (8%)
Query: 40 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWS---IDPRVIILVNTPTQYSIMI 95
V+ G+S+ L C I RV W L A +DK+ ID +I +N
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPA-SDKYRMTFIDSVAVIQMN--------- 5484
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
N+ D G + C Q + +IV+ PP + + + + V+L C G
Sbjct: 5485 -NLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 5543
Query: 156 PEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQS--GEYECSALNDVAAPDVRKV 209
P V W R L + S++ + I + D S GEY C A N+V + D
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS-DTCVC 5602
Query: 210 KITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 268
+ + PP ++SK + V G+ L QW KE+ + + +RI
Sbjct: 5603 TVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFV 5662
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVID 312
++TL F + G Y C N G A++ + P +++
Sbjct: 5663 ENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVE 5708
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/292 (23%), Positives = 114/292 (39%), Gaps = 32/292 (10%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 89
F K ++ V V G+SA+L+C + V+W Y G+ K + P ++
Sbjct: 7963 FVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW-------YKGDTK--LRPTTTYKMHFRN 8013
Query: 90 QYSIMIQN-VDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGSS 145
+ ++ N VD+ D G Y C + ++ L VQ +PP D+ G
Sbjct: 8014 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLP 8073
Query: 146 VTLLCLAIGRPEPTVTWRHLSVKEGQ----------GFVSEDEYLEISDIKRDQSGEYEC 195
V C G +V+W K+G+ F+ L I R +G+Y C
Sbjct: 8074 VVFDCAISGSEPISVSW----YKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSC 8129
Query: 196 SALNDV--AAPDVRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 252
+A N + A+ R + PP+ + VG+ C + + W K+
Sbjct: 8130 TATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKD 8189
Query: 253 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +G +I + LT V + D G YTC A N++G + + L
Sbjct: 8190 SREIRSG-GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 8240
Score = 73.6 bits (179), Expect = 2e-13
Identities = 68/285 (23%), Positives = 112/285 (39%), Gaps = 26/285 (9%)
Query: 33 KAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 91
+ ++ + V G A C I R W +Y +DK SI I
Sbjct: 3460 RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE-SDKCSIRSSKYIS------- 3511
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ--VPPQIMNISSDITVNEGSSVTLL 149
S+ I V D G YTC + + L V PP ++ +T G + +
Sbjct: 3512 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFI 3571
Query: 150 CLAIGRPEPTVTWRHLSVKEGQGF-------VSEDE---YLEISDIKRDQSGEYECSALN 199
C G P W+ K+G +S+ E LE+S++ G Y C A N
Sbjct: 3572 CTVTGTPVIETIWQ----KDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASN 3627
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
A + I ++ P +I + + ++ +K L C+ W K+ +L G
Sbjct: 3628 KFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPG 3687
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
D +I + +++TL KD G Y C A+N+ G+++ S T+
Sbjct: 3688 KD-YKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 3731
Score = 72.4 bits (176), Expect = 5e-13
Identities = 66/285 (23%), Positives = 114/285 (40%), Gaps = 20/285 (7%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDD-RVTRVAWL-NRSTILYAGNDKWSIDPRVIILVNTP 88
F K + + + G++ LR ++ + V WL +R ++ + S + R+ + N
Sbjct: 6553 FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVI-----RESENTRISFIDNIA 6607
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
T + + + + + G Y C ++ D + L V P +I+ +TV G+ L
Sbjct: 6608 T---LQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFAL 6664
Query: 149 LCLAIGRPEPTVTW----RHLSV--KEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVA 202
C+ G PE + W R LS K F+++ L+I + G Y N V
Sbjct: 6665 ECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724
Query: 203 APDVR---KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
+ V + P +I K K+ +G +L C S WF++ + +G
Sbjct: 6725 KSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSG 6784
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ + TL + D G YTCVA N G+ S L
Sbjct: 6785 -PKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 6828
Score = 72.0 bits (175), Expect = 7e-13
Identities = 66/289 (22%), Positives = 113/289 (39%), Gaps = 20/289 (6%)
Query: 38 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
+ +R G+S T C I RV+W GN+ +I I ++ + I
Sbjct: 4871 LVLRNGQSTTFECQITGTPKIRVSWY------LDGNEITAIQKHGISFIDGLATFQISGA 4924
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 156
V+ + G Y C + D + + L V+ PP + + V + S V L C G P
Sbjct: 4925 RVE--NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTP 4982
Query: 157 EPTVTW--RHLSVKEGQGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
VTW + ++ + + D L I+ +GEY+C N+ + +
Sbjct: 4983 PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSC-STR 5041
Query: 211 ITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 269
+ + PP +I K +NT + + P W K++ L D + I
Sbjct: 5042 VALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDED-DNVYISFVD 5100
Query: 270 RMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVIDGVNS 316
++TL +V G YTC A N+ G A + + P +++ S
Sbjct: 5101 SVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKS 5149
Score = 72.0 bits (175), Expect = 7e-13
Identities = 67/282 (23%), Positives = 102/282 (36%), Gaps = 19/282 (6%)
Query: 41 RQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVD 99
+QGES L C I +V+W + L+ + W + I V T I
Sbjct: 6377 KQGESIQLECKISGSPEIKVSWFRNDSELH---ESWKYNMSFINSVALLT-----INEAS 6428
Query: 100 VYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPT 159
D G Y C + L V+ PP S + +GS V L C G P
Sbjct: 6429 AEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFE 6488
Query: 160 VTW--RHLSVKEGQGFVSE----DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 213
V W V+ + F D L I +++ GEY C A N+V + D +
Sbjct: 6489 VVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGS-DTCSCSVKF 6547
Query: 214 NYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMS 272
PP ++ K +T +G L W K+ + + RI ++
Sbjct: 6548 KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIA 6607
Query: 273 TLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVID 312
TL + + G Y C N G +A +T+ P +I+
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIE 6649
Score = 70.9 bits (172), Expect = 2e-12
Identities = 70/281 (24%), Positives = 112/281 (39%), Gaps = 25/281 (8%)
Query: 38 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGND-KWSIDPRVIILVNTPTQYSIMI 95
+TV GE+ TL C + V W +L + K+S ++ S+ I
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS---------SLRI 5763
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIV----QVPPQIMNISSDITVNEGSSVTLLCL 151
+V+ D G YT VQ +N K+S ++ VPP + G+S L C
Sbjct: 5764 LSVERQDAGTYTFQVQ-NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK 5822
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYECSALNDVAAPD 205
G +V W H K G + + L+++ + G Y C A N VA D
Sbjct: 5823 VAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN-VAGSD 5881
Query: 206 VRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ +TV PP ++ + + V G+ + P + WF+ L G D
Sbjct: 5882 ECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCN 5940
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
I + ++ L FN+ G YTCV +N G + + L+
Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLF 5981
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/220 (25%), Positives = 91/220 (41%), Gaps = 8/220 (3%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
SI I NVD D G Y C D T + ++ PP+ + SDI+ G V L
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTT 7514
Query: 152 AIGRPEPTVTW---RHLSVKEGQG-FVSEDE---YLEISDIKRDQSGEYECSALNDVAAP 204
G +V W + V+E ++S E L+ S ++ +G+Y C ND
Sbjct: 7515 IEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQ 7574
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ + + K ++ V+ G L C + P +WFK+ L T + +
Sbjct: 7575 ECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKEL-TSDNKYK 7633
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
I ++S L NV+ D G Y+ N +G + + +L
Sbjct: 7634 ISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 7673
Score = 69.7 bits (169), Expect = 3e-12
Identities = 72/291 (24%), Positives = 104/291 (35%), Gaps = 30/291 (10%)
Query: 31 FPKAMDNVTVRQGESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDP--RVIILVN 86
F ++ + G+S +L+C + +T V+W Y G+ K P R N
Sbjct: 6081 FVTELEPLEAAVGDSVSLQCQVAGTPEIT-VSW-------YKGDTKLRPTPEYRTYFTNN 6132
Query: 87 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEG 143
T ++ V++ D G YTC + +S+ +Q +PP DI G
Sbjct: 6133 VAT---LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVG 6189
Query: 144 SSVTLLCLAIGRPEPTVTWRHLSV------KEGQGFVSEDEYLEISDIKRDQSGEYECSA 197
VTL C G V W V FV L+I SG+Y CSA
Sbjct: 6190 LPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSA 6249
Query: 198 LNDVAAPDVRKVKITVNYP---PYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 253
N + ++T P P+ K + V G+ C + W K+
Sbjct: 6250 SNPLGTAS-SSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 6308
Query: 254 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ G I G L V + D G YTC ATN +G S L
Sbjct: 6309 KEIRPG-GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Score = 69.7 bits (169), Expect = 3e-12
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 34/241 (14%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP---PQIMNISSDITVNEGSSVTLL 149
+ ++ + D G YTC V D ++++ P P + +TV+EG V L
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLS 8366
Query: 150 CLAIGRPEPTVTWRHLSVKEGQ----------GFVSEDEYLEISDIKRDQSGEYECSALN 199
C G + W +K G+ F S LE+ D+ + SG+Y C A N
Sbjct: 8367 CHVQGSEPIRIQW----LKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN 8422
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILS----------------CEASAVP 243
VA D K K+T+ P ++ A G+ +S + P
Sbjct: 8423 -VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481
Query: 244 MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT 303
+ +W K + R + I KG + L + ++ D G Y CVA N+ G +++
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVN 8541
Query: 304 L 304
L
Sbjct: 8542 L 8542
Score = 68.2 bits (165), Expect = 1e-11
Identities = 62/287 (21%), Positives = 111/287 (38%), Gaps = 21/287 (7%)
Query: 29 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 87
A F K +++ ++ +G+ L T V W ++ P + T
Sbjct: 7868 AKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGI---------NVTPSQRCNITT 7918
Query: 88 PTQYSIM-IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 146
+ +I+ I + V D G Y C ++ + + +++ PP + + V+ G S
Sbjct: 7919 TEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSA 7978
Query: 147 TLLCLAIGRPEPTVTWRHLSVK------EGQGFVSEDEYLEISDIKRDQSGEYECSALN- 199
+L C G PE V+W K F + L + + + SGEY C A N
Sbjct: 7979 SLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENS 8038
Query: 200 --DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
+V+A V+ P + + ++ +VG + C S W+K+ L
Sbjct: 8039 VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++ +TL F G Y+C ATN +G+ ++S L
Sbjct: 8099 DS-PNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 67.8 bits (164), Expect = 1e-11
Identities = 72/306 (23%), Positives = 119/306 (38%), Gaps = 49/306 (16%)
Query: 38 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
VTV+ G+ A I R +++W +L G ++ +Y++++
Sbjct: 3248 VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK--------CKFLHDGQEYTLLLI 3299
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV-------------PPQIMNISSDITVNEG 143
D YTC + D T+ L V+V PP I+ D +EG
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEG 3359
Query: 144 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF---VSEDEY-LEISDIKRDQSGEYECSA 197
C G + V+W + +K + F ED Y LEI++ + G Y A
Sbjct: 3360 QPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3418
Query: 198 LNDVA-----------APD-------VRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCE 238
N V AP+ +++++ + P I K + V++G +CE
Sbjct: 3419 SNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478
Query: 239 ASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNT 298
+ P FQWFK + D I + +S+L D G YTC A+N+ G+
Sbjct: 3479 IQSAPNVRFQWFKAGREIYES-DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 299 NASITL 304
+ + TL
Sbjct: 3538 SCTATL 3543
Score = 67.0 bits (162), Expect = 2e-11
Identities = 48/217 (22%), Positives = 85/217 (39%), Gaps = 8/217 (3%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ + N+++ D YTC V L V+ PP + S+V +
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAI 5352
Query: 152 AIGRPEPTVTWRHLSVKEGQG------FVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
G P + W V+ G +L + + ++G+Y C NDV +
Sbjct: 5353 LKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDS 5412
Query: 206 VRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ + P ++ K + + V G L C+ + P WF+ E L D R
Sbjct: 5413 CTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPAS-DKYR 5471
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 301
+ ++ + N+S +D G++ C A N G+T+ S
Sbjct: 5472 MTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 5508
Score = 66.2 bits (160), Expect = 4e-11
Identities = 63/288 (21%), Positives = 113/288 (39%), Gaps = 23/288 (7%)
Query: 29 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 87
ATF K + + +V G L T V+W+ + L + +++ SI T
Sbjct: 6927 ATFVKRLADFSVETGSPIVLEATYTGTPPISVSWI-KDEYLISQSERCSI---------T 6976
Query: 88 PTQYSIMIQNVD--VYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSS 145
T+ S +++ ++ + D Y+C ++ + + V PP + + G
Sbjct: 6977 MTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEP 7036
Query: 146 VTLLCLAIGRPEPTVTW--RHLSVKEGQG----FVSEDEYLEISDIKRDQSGEYECSALN 199
TL C G PE ++W H ++ F + L I+ + GEY C A N
Sbjct: 7037 ATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADN 7096
Query: 200 DVAAPDVRKVKITV--NYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 256
V A V + PP+ + K K+ ++G C + + W+K+ L
Sbjct: 7097 SVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLL 7156
Query: 257 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ ++ ++TL + G Y C A+N LG ++S L
Sbjct: 7157 KDDAN-LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203
Score = 66.2 bits (160), Expect = 4e-11
Identities = 57/226 (25%), Positives = 94/226 (41%), Gaps = 17/226 (7%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV---QVPP--QIMNISSDITVNEGSSV 146
++ I D G Y CS +S LI+ +VPP + +S D+ + G S
Sbjct: 7172 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLAL--GESG 7229
Query: 147 TLLCLAIGRPEPTVTWR--HLSVKEGQGF----VSEDEYLEISDIKRDQSGEYECSALND 200
T C G +TW + ++ G + V L + + + +G+Y C A N
Sbjct: 7230 TFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASN- 7288
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGIL--SCEASAVPMAEFQWFKEETRLAT 258
+A D ++ V PP K V Q C+ P + W+K+ET +
Sbjct: 7289 IAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQE 7348
Query: 259 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
R+ ++ L N+S +D G+YTC A N G+ ++S +L
Sbjct: 7349 S-SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 7393
Score = 66.2 bits (160), Expect = 4e-11
Identities = 70/283 (24%), Positives = 115/283 (40%), Gaps = 32/283 (11%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGND-KWSIDPRVIILVNTPT 89
F + +++ TV + + A C + V W + G K+ D +
Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSI-------- 12876
Query: 90 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ-VPPQIMNISSDITVNEGSSVTL 148
+ ++I++ + DE Y C V+ + SR L V+ +P +I+ DI G+ V
Sbjct: 12877 -HRLIIKDCRLDDECEYACGVED----RKSRARLFVEEIPVEIIRPPQDILEAPGADVVF 12931
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQG----FVSEDEY--LEISDIKRDQSGEYECSALNDVA 202
L + + + V W ++ QG +SE + L+I DIK GEY A + A
Sbjct: 12932 LA-ELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEA 12990
Query: 203 APDVRKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
+ K+ + P I A ++ V VG+ + A P AE +WFKE L+T
Sbjct: 12991 -----RAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST--- 13042
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
I+ ++ + D G Y V NK G I L
Sbjct: 13043 -KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINL 13084
Score = 64.3 bits (155), Expect = 1e-10
Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 29/285 (10%)
Query: 31 FPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 89
F K + NV + L C I + RV+W + A +D++ R+ + T
Sbjct: 4115 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEI-AASDRY----RIAFVEGTA- 4168
Query: 90 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLL 149
S+ I VD+ D G +TC K S LIVQ PP + V GS+V L
Sbjct: 4169 --SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226
Query: 150 CLAIGRPEPTVTW---RHLSVKEGQGFVSE---DEYLEISDIKRDQSGEYECSALNDVAA 203
G T+ W V G ++++ + LE+ +K SG Y C N
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286
Query: 204 PDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ ++ K + + + G L+C+ + P + WF + +
Sbjct: 4287 VECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI------ 4340
Query: 263 MRIENKGRMS------TLTFFNVSEKDYGNYTCVATNKLGNTNAS 301
+ +K RMS L +V +D G Y C A N+ G+ + S
Sbjct: 4341 -KESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 4384
Score = 63.9 bits (154), Expect = 2e-10
Identities = 68/287 (23%), Positives = 114/287 (39%), Gaps = 37/287 (12%)
Query: 37 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
+V V + + TL C + +V WL + K + R + S I
Sbjct: 5149 SVDVTEKDPMTLECVVAGTPELKVKWLK--------DGKQIVPSRYFSMSFENNVASFRI 5200
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIV---QVPPQIMNISSDITVNEGSSVTLLCLA 152
Q+V D G YT V+ D + +L V +PP + + GSS+ + C
Sbjct: 5201 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKV 5260
Query: 153 IGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSALNDVA 202
G + W K+G+ + +Y LE+++++ + + Y C N VA
Sbjct: 5261 SGSLPISAQW----FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSN-VA 5315
Query: 203 APDVRKVKITVNYPP--YISKAKNTGV---SVGQKGILSCEASAVPMAEFQWFKEETRLA 257
D +TV PP + + + +V K IL P + +WFK++ L
Sbjct: 5316 GDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILK----GTPPFKIKWFKDDVELV 5371
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+G I +G S L ++V G YTC TN +G+ + + L
Sbjct: 5372 SGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTML 5417
Score = 63.5 bits (153), Expect = 3e-10
Identities = 57/219 (26%), Positives = 80/219 (36%), Gaps = 12/219 (5%)
Query: 95 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 154
I ++ D G YTCS HL V+ PP + VN + V L L G
Sbjct: 4734 ISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGG 4793
Query: 155 RPEPTVTW----RHLSVKEGQGFVSED--EYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
T+ W + L + +D LE+ K SG Y C NDV K
Sbjct: 4794 TAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTA-TSK 4852
Query: 209 VKITVNYPPYISKAKNTGVSV---GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 265
+ V PP K K + V V GQ C+ + P W+ + + T + I
Sbjct: 4853 ATLFVKEPPQFIK-KPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEI-TAIQKHGI 4910
Query: 266 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++T ++ G Y C A N G + SI L
Sbjct: 4911 SFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 4949
Score = 63.2 bits (152), Expect = 3e-10
Identities = 62/279 (22%), Positives = 100/279 (35%), Gaps = 16/279 (5%)
Query: 25 RSGDATFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVII 83
R+ +F + + N G S L C + VAW + T + +G +
Sbjct: 5796 RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQT------- 5848
Query: 84 LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
+ ++ + ++D D G YTC R L VQ PP + + V G
Sbjct: 5849 -TFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPG 5907
Query: 144 SSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEY--LEISDIKRDQSGEYECSA 197
+VT + G P V W R L + ED LE+ +I QSGEY C
Sbjct: 5908 KNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVV 5967
Query: 198 LNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
N+ ++ + + V G+ IL + W K+ +
Sbjct: 5968 SNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNIT 6027
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
T + I + L N +++D G Y+C N+ G
Sbjct: 6028 TS-EKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAG 6065
Score = 62.8 bits (151), Expect = 4e-10
Identities = 64/293 (21%), Positives = 105/293 (35%), Gaps = 36/293 (12%)
Query: 22 VPVRSGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPR 80
V VR + K + + GESA L C + V +V W N+K +
Sbjct: 3731 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK--------NNKELSESN 3782
Query: 81 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV 140
+ + ++ + I +V V D G Y+C D + ++++ PP + +
Sbjct: 3783 TVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADI 3842
Query: 141 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQS 190
G++ L C G ++W K+ + S +Y LEI
Sbjct: 3843 VRGTNALLQCEVSGTGPFEISW----FKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADV 3898
Query: 191 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWF 250
GEYEC N+V + P ++ K + GQ L W
Sbjct: 3899 GEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 3958
Query: 251 KEETRLATGLDGMRIENKGRMS------TLTFFNVSEKDYGNYTCVATNKLGN 297
K G + +R + K +MS L +V G YTC+A N+ G+
Sbjct: 3959 K-------GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS 4004
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/221 (21%), Positives = 88/221 (39%), Gaps = 8/221 (3%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ I N++ D G Y C + T + + PP+ + SD + G +V L +
Sbjct: 6514 SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAI 6573
Query: 152 AIGRPEPTVTW---RHLSVKEGQG----FVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
G +V W R ++E + F+ L++ + SG+Y C ND
Sbjct: 6574 VEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMR 6633
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ V + I K + V+ G L C + P +WFK+ L+
Sbjct: 6634 ECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSAD-SKHH 6692
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
I ++++L D G Y+ N +G +N +++++
Sbjct: 6693 ITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVH 6733
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/224 (25%), Positives = 94/224 (41%), Gaps = 12/224 (5%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGSSVTL 148
S+ I ++ D+G Y+ V+ V + V VPP + D+ G+SV L
Sbjct: 6701 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 6760
Query: 149 LCLAIGRPEPTVTWRH-----LSVKEGQGFVSEDEY-LEISDIKRDQSGEYECSALNDVA 202
C G +V W +S + Q SE+ L +S ++ +G Y C A N VA
Sbjct: 6761 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAAN-VA 6819
Query: 203 APDVRKVKITVNYPPYISKAKNT-GVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
D +TV PP + ++ V G + P + +WFK L G +
Sbjct: 6820 GSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG-E 6878
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
I + ++ L F V + G+Y+C+ TN G+ + + L+
Sbjct: 6879 SCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 6922
Score = 58.9 bits (141), Expect = 6e-09
Identities = 56/254 (22%), Positives = 92/254 (36%), Gaps = 30/254 (11%)
Query: 74 KWSIDPRVIILVNTPTQYSIMIQN---------VDVYDEGPYTCSVQTD---NHPKTSRV 121
KW D R ++ +Y I +N +++D G YT + + + +T+
Sbjct: 4049 KWYKDGRPLV---ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT 4105
Query: 122 HLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY-- 179
L + P ++ + L C G V+W K+G+ + D Y
Sbjct: 4106 VLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSW----FKDGKEIAASDRYRI 4161
Query: 180 --------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQ 231
LEI + + +G + C A N V + D I P +++K + V G
Sbjct: 4162 AFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGS 4221
Query: 232 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
L +WFK L +G I + S+L + V D G YTC
Sbjct: 4222 AVCLKSTFQGSTPLTIRWFKGNKELVSG-GSCYITKEALESSLELYLVKTSDSGTYTCKV 4280
Query: 292 TNKLGNTNASITLY 305
+N G S L+
Sbjct: 4281 SNVAGGVECSANLF 4294
Score = 58.5 bits (140), Expect = 8e-09
Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 19/285 (6%)
Query: 29 ATFPKAMD-NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVN 86
ATF + ++ + +++G++ L C + ++ W + K S R+ + +
Sbjct: 4299 ATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI-----KESSKHRMSFVES 4353
Query: 87 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 146
T + + +V + D G Y C Q + +IV+ P I V + V
Sbjct: 4354 TAV---LRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDV 4410
Query: 147 TLLCLAIGRPEPTVTW--RHLSVKEGQGFVS--EDEYLEISDIK--RDQSGEYECSALND 200
LL G P +TW + ++ G+ + + +D + + +K +GEY+C N+
Sbjct: 4411 MLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE 4470
Query: 201 VAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
V + + ++T+ PP +I K ++T G W K+ + T
Sbjct: 4471 VGS-SICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEI-TE 4528
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
D +R+ + +++L + K G Y C A N G S L
Sbjct: 4529 DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 4573
Score = 57.4 bits (137), Expect = 2e-08
Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 9/204 (4%)
Query: 109 SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK 168
S+ + KTS+ V+ +I S+ +++NEG + L G + + +
Sbjct: 33019 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELT 33078
Query: 169 EGQ----GFVSEDEYLEISDIKRDQSGEYECSALNDVAAP----DVRKVKITVNYPPYIS 220
+ G D+ L I G C + D+ K + P +IS
Sbjct: 33079 NSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFIS 33138
Query: 221 KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVS 280
+ ++ ++ GQ + +CE S P E +WFK ++ + I + +L N S
Sbjct: 33139 QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISIS-SNVSISRSRNVYSLEIRNAS 33197
Query: 281 EKDYGNYTCVATNKLGNTNASITL 304
D G YT A N G +A+ +L
Sbjct: 33198 VSDSGKYTIKAKNFRGQCSATASL 33221
Score = 54.3 bits (129), Expect = 2e-07
Identities = 61/245 (24%), Positives = 91/245 (37%), Gaps = 58/245 (23%)
Query: 117 KTSRVHLIVQVP---PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR------HLSV 167
+T+RV V++P P +++ ++TV EG SVTL C G P PTVTW S+
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 168 KEGQGFVSEDEYLEISDIKRDQSGEYECSALND---VAAPDVRKVKITVNY--------- 215
F S L I + + SG + CSA+N+ V+ V+++ +
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1047
Query: 216 ----------------------------------PPYISKAKNTGVSVGQKGILSCEASA 241
P +I+K + G + C+
Sbjct: 1048 KFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107
Query: 242 VPMAEFQWFKEETRLATGLDGMRIENK--GRMSTLTFFNVSEKDYGNYTCVATNKLGNTN 299
P W K L TG NK G + ++ D G YT V NK G T+
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFAD-DAGEYTIVVRNKHGETS 1166
Query: 300 ASITL 304
AS +L
Sbjct: 1167 ASASL 1171
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/253 (22%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 59 VAWLNRSTILYAGND-KWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPK 117
+ W +TIL +G K I ++ S+ I D G Y C V +
Sbjct: 4424 ITWFKDNTILRSGRKYKTFIQDHLV---------SLQILKFVAADAGEYQCRVTNEVGSS 4474
Query: 118 TSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSED 177
+ ++ PP + + G + G TVTW +K+ +D
Sbjct: 4475 ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW----LKDSDEITEDD 4530
Query: 178 EY----------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS-KAKNTG 226
L +S I+ G+Y C A ND + ++V P I+ +A +
Sbjct: 4531 NIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL-LSVKEPATITEEAVSID 4589
Query: 227 VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGN 286
V+ G L + S +WFK+ L G +I +S L + +KD G
Sbjct: 4590 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLG-SKYKISVTDTVSILKIISTEKKDSGE 4648
Query: 287 YTCVATNKLGNTN 299
YT N +G ++
Sbjct: 4649 YTFEVQNDVGRSS 4661
Score = 53.9 bits (128), Expect = 2e-07
Identities = 69/289 (23%), Positives = 120/289 (41%), Gaps = 36/289 (12%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDDRVT----RVAWLNRSTILYAGNDKWSIDPRVIILV 85
T K ++N TV + A ID ++ +++W Y G +K + I +
Sbjct: 8657 TLIKDIENQTVLKDNDAVFE--IDIKINYPEIKLSW-------YKGTEKLEPSDKFEISI 8707
Query: 86 NTPTQYSIMIQNVDVYDEGPY--TCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
+ ++++ ++N + D+G Y C P + L V P ++ D+T+ EG
Sbjct: 8708 DGD-RHTLRVKNCQLKDQGNYRLVCG------PHIASAKLTVIEPAWERHLQ-DVTLKEG 8759
Query: 144 SSVTLLCLAIGRPEPTVTW-RHLSVKEGQG-FVSEDEY----LEISDIKRDQSGEYECSA 197
+ T+ C P W R+ + + QG +E E+ L I+D++ + G+Y C
Sbjct: 8760 QTCTMTC-QFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKY 8818
Query: 198 LNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
+ + ++R I + + +N VS Q CE S A W+K T L
Sbjct: 8819 EDLETSAELR---IEAEPIQFTKRIQNIVVSEHQSATFECEVS-FDDAIVTWYKGPTEL- 8873
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA-TNKLGNTNASITLY 305
T N GR +T NV+ D G Y+ +A G ++ LY
Sbjct: 8874 TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELY 8922
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/285 (26%), Positives = 108/285 (37%), Gaps = 32/285 (11%)
Query: 13 TTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRST-ILYAG 71
T A LF+ PV F K +++ TV +G +A L C + +V W T IL +
Sbjct: 12274 THANLFVKEPPVE-----FTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSK 12328
Query: 72 NDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI 131
+ D RV LV I + D YTC + KTS +V +
Sbjct: 12329 KYEIVADGRVRKLV---------IHDCTPEDIKTYTCDAKDF---KTSCNLNVVPPHVEF 12376
Query: 132 MNISSDITVNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF--VSED--EYLEISDI 185
+ +D+ V E C + R V W +K+G+ + +S+ L I+
Sbjct: 12377 LRPLTDLQVREKEMARFEC-ELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKC 12435
Query: 186 KRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMA 245
D EY C A + + + N VS L CE S P A
Sbjct: 12436 LLDDEAEYSCEVR---TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSK-PGA 12491
Query: 246 EFQWFK-EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 289
E W+K +E + TG I +GR L N +D GNY C
Sbjct: 12492 EVIWYKGDEEIIETG--RYEILTEGRKRILVIQNAHLEDAGNYNC 12534
Score = 52.8 bits (125), Expect = 4e-07
Identities = 53/231 (22%), Positives = 92/231 (39%), Gaps = 25/231 (10%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G YT + T V+ PPQ++ +TV G + GRP+P ++
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVN--APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271
Query: 162 WRHLSVKEGQGFVSE-----DEY-LEISDIKRDQSGEYECSALND-----------VAAP 204
W GF + EY L + + + + Y C A ND V P
Sbjct: 3272 WYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3331
Query: 205 DV--RKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+V ++ V P I+ ++T S GQ C S + + W+ ++ ++
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPS-RF 3389
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVI 311
R+ L +D G YT VA+N +G ++ A+++L P +++
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3440
Score = 52.8 bits (125), Expect = 4e-07
Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 208 KVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIE 266
K K+T P I K K+ +G+ LSC+ P+ + +W++ L ++
Sbjct: 30524 KTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK-YKMS 30582
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ GR TLT ++D G YTC+ATN++G S L
Sbjct: 30583 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 30620
Score = 48.9 bits (115), Expect = 6e-06
Identities = 62/282 (21%), Positives = 112/282 (39%), Gaps = 38/282 (13%)
Query: 28 DATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNT 87
+A F K + N+ V + ++ L C + V W Y G+++ R IL
Sbjct: 12462 EAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIW-------YKGDEEIIETGRYEILTEG 12514
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 147
+ ++IQN + D G Y C + + +VH ++ + ++ ++ + EG
Sbjct: 12515 RKRI-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---ELAAEFISKPQNLEILEGEKAE 12570
Query: 148 LLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR----------DQSGEYECSA 197
+C +I + V W+ ++ + S D+Y I+D K+ G Y
Sbjct: 12571 FVC-SISKESFPVQWK----RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 12625
Query: 198 LNDVAAPD---VRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEET 254
AA + K++I V K+T V Q+ + +CE + A+ +WF+ E
Sbjct: 12626 GAARAAAHLTVIEKLRIVV-------PLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEE 12677
Query: 255 RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ + I K + TL + D NY TN G
Sbjct: 12678 AIFDSSKYI-ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 12718
Score = 48.5 bits (114), Expect = 8e-06
Identities = 75/314 (23%), Positives = 124/314 (39%), Gaps = 50/314 (15%)
Query: 6 YWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS 65
Y + + TTA+L + + + F + +VTV + A C + R V W
Sbjct: 11468 YQALNAITTAILTVKEI-----ELDFAVPLKDVTVPERRQARFECVLT-REANVIWSKGP 11521
Query: 66 TILYAGNDKWSI--DPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHL 123
I+ + +DK+ I D + ILV +Q+ DEG YT V+ KTS
Sbjct: 11522 DIIKS-SDKFDIIADGKKHILVINDSQFD---------DEGVYTAEVEGK---KTSARLF 11568
Query: 124 IVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK-----------EGQG 172
+ + + M+ D TV EG + T +C + + V W K EG+
Sbjct: 11569 VTGIRLKFMSPLEDQTVKEGETATFVC-ELSHEKMHVVWFKNDAKLHTSRTVLISSEGKT 11627
Query: 173 FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQK 232
E + + + DI + ++ E S+ ++K+ P + K + +
Sbjct: 11628 HKLEMKEVTLDDISQIKAQVKELSS--------TAQLKVLEADPYFTVKLHDKTAVEKDE 11679
Query: 233 GILSCEASA-VPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC-V 290
L CE S VP+ +WFK+ + I+ G L KD G Y C
Sbjct: 11680 ITLKCEVSKDVPV---KWFKDGEEIVPS-PKYSIKADGLRRILKIKKADLKDKGEYVCDC 11735
Query: 291 ATNKLGNTNASITL 304
T+K T A++T+
Sbjct: 11736 GTDK---TKANVTV 11746
Score = 48.1 bits (113), Expect = 1e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 26 SGDAT-FPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLN-RSTILYAGNDKWSIDPRVI 82
SG+A K M +VT + GE+A L C I R + + W ++ + K S D R
Sbjct: 30529 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRT- 30587
Query: 83 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI---MNISSDIT 139
+++ + + DEG YTC + + L++Q PQ +
Sbjct: 30588 --------HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY 30639
Query: 140 VNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 184
GS++ L + IGRP P +TW H GQ + E + I +
Sbjct: 30640 GAVGSTLRLHVMYIGRPVPAMTWFH-----GQKLLQNSENITIEN 30679
Score = 47.8 bits (112), Expect = 1e-05
Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 15/184 (8%)
Query: 129 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEGQGFVSED---EYLEI 182
P I D+T G + L C +GRP P + W ++ + +S D L +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 183 SDIKRDQSGEYECSALNDVAAPDVRKVKITVN-----YPPYISKAKNTGVSVGQKGILSC 237
+++ G Y C A N+V + K+ + +P Y K K G +VG L
Sbjct: 30593 MTEEQEDEGVYTCIATNEVGEVETSS-KLLLQATPQFHPGYPLKEKYYG-AVGSTLRLHV 30650
Query: 238 EASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDY-GNYTCVATNKLG 296
P+ WF + +L + + IEN + L NV K + G Y +N G
Sbjct: 30651 MYIGRPVPAMTWFHGQ-KLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 30709
Query: 297 NTNA 300
+A
Sbjct: 30710 TVDA 30713
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/186 (22%), Positives = 73/186 (39%), Gaps = 20/186 (10%)
Query: 138 ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ------------GFVSEDEYLEISDI 185
+ V EGS+ T G P P V+W ++GQ F L I +
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSW----FRDGQVISTSTLPGVQISFSDGRAKLTIPAV 70
Query: 186 KRDQSGEYECSALN---DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAV 242
+ SG Y A N + VK P ++ + ++ V G + L + +
Sbjct: 71 TKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 243 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
P +++++ + + LD +I +G + +L +D G Y+ ATN +G ++
Sbjct: 131 PTPVVKFYRDGAEIQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 303 TLYGPG 308
L G
Sbjct: 190 ELLVQG 195
Score = 47.0 bits (110), Expect = 2e-05
Identities = 64/300 (21%), Positives = 114/300 (38%), Gaps = 35/300 (11%)
Query: 13 TTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGN 72
TTA L + G V F K + ++ V + S L C + W + L + N
Sbjct: 2256 TTAKLIVEGAVVE-----FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKS-N 2309
Query: 73 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 132
K++I R + ++ +++V D+G Y+ + D T ++ + + P I+
Sbjct: 2310 GKYTITSR-------RGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPR-PIAIL 2359
Query: 133 NISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEI 182
SD V EG V L + + W +K+GQ D L I
Sbjct: 2360 QGLSDQKVCEGDIVQLE-VKVSLESVEGVW----MKDGQEVQPSDRVHIVIDKQSHMLLI 2414
Query: 183 SDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAV 242
D+ ++ +G Y + A +++V I+ K+ V G K +L C+ S
Sbjct: 2415 EDMTKEDAGNYSFTI---PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVP 2471
Query: 243 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
+ +W+ + ++ D ++ KG L D G Y + N N S+
Sbjct: 2472 DVTSVKWYLNDEQIKPD-DRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSV 2530
Score = 45.4 bits (106), Expect = 7e-05
Identities = 67/286 (23%), Positives = 116/286 (40%), Gaps = 29/286 (10%)
Query: 33 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS 92
+ + +VTV GE+AT C + V W + L + + PR V+T T
Sbjct: 12200 RPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSD---KVVPRSEGKVHTLT--- 12253
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP-QIMNISSDITVNEGSSVTLLCL 151
+++V + D G VQ + +L V+ PP + D TV EG++ L C
Sbjct: 12254 --LRDVKLEDAG----EVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLEC- 12306
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN-DVAAPDVRKVK 210
+ R V W K G + +Y ++D + + ++C+ + D + K
Sbjct: 12307 EVSRENAKVKW----FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 12362
Query: 211 ITVN---YPPYISKAKN-TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLDGMR 264
+ N PP++ + T + V +K + CE S A+ +WFK+ + G
Sbjct: 12363 TSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGAEIKKG-KKYD 12420
Query: 265 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAV 310
I +KG + L D Y+C + T+ +T+ AV
Sbjct: 12421 IISKGAVRILVINKCLLDDEAEYSCEV--RTARTSGMLTVLEEEAV 12464
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 188 DQSGEYECSALN----DVAAPDVRKVKITV---NYPPYISKAKNTGVSVGQKGILSCEAS 240
++ +Y+ A+ +++ P +T+ N PP I +SV K +L+ +A
Sbjct: 19257 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRID------LSVAMKSLLTVKAG 19310
Query: 241 A----------VPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCV 290
PM W K+ T L +G+++ + + TL F+V+ KD G+YT
Sbjct: 19311 TNVCLDATVFGKPMPTVSWKKDGTLLKPA-EGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369
Query: 291 ATNKLGNTNASITL 304
A N G+ +A+I L
Sbjct: 19370 AENSSGSKSATIKL 19383
Score = 44.7 bits (104), Expect = 1e-04
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 127 VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSED----E 178
+PP+I + SDI+++EG +T+ C G P P VTW R + +E F E+
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 33386
Query: 179 YLEISDIKRDQSGEYECSALND 200
L I D+++ G Y S N+
Sbjct: 33387 TLIIMDVQKQDGGLYTLSLGNE 33408
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/202 (21%), Positives = 75/202 (37%), Gaps = 25/202 (12%)
Query: 129 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQG-----FVSEDEYLE-- 181
P+I TV +GS +G+P+P W VK + + ED E
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 182 ISDIKRDQSGEYECSALNDVAAPD---------VRKVKITVNYPPYISKAKNTGVSVGQK 232
I D+ + S A+N + + T ++K K+T
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT------M 2191
Query: 233 GILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVAT 292
CE S P + +W+K+ + G D R+ + ++ L+ + D +Y+CV
Sbjct: 2192 ATFECETSE-PFVKVKWYKDGMEVHEG-DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 293 NKLGNTNASITLYGPGAVIDGV 314
N + L GAV++ V
Sbjct: 2250 ED-ENVKTTAKLIVEGAVVEFV 2270
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 6/142 (4%)
Query: 166 SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD---VRKVKITVNYPPYISKA 222
SV+E + ++E +S + S E + +AL + + + RK+K T+ ++K
Sbjct: 32510 SVREVKSQMTETRE-SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLA-ARILTKP 32567
Query: 223 KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK 282
++ V G+ SC+ P+ W ++ L+T K + ST +V
Sbjct: 32568 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQAS 32626
Query: 283 DYGNYTCVATNKLGNTNASITL 304
D GNY+ V N G A TL
Sbjct: 32627 DEGNYSVVVENSEGKQEAEFTL 32648
Score = 43.1 bits (100), Expect = 4e-04
Identities = 52/228 (22%), Positives = 78/228 (34%), Gaps = 29/228 (12%)
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEP 158
+VYD Y C + + +++ PP+ + T G +V PEP
Sbjct: 31663 EVYD---YYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 31719
Query: 159 TVTWRHLSVKEGQGFVSEDE-------------YLEISDIKRDQSGEYECSALNDVAAPD 205
VTW K GQ D L I+ + D EY A N
Sbjct: 31720 HVTW----YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 31775
Query: 206 VR-KVKITVNYPPYISKAK--------NTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 256
+ K+ +T++ PP S + N GQ S +P +W K+ L
Sbjct: 31776 CKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPL 31835
Query: 257 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ G + I L + +D G Y ATN G+T+ L
Sbjct: 31836 SLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 31883
Score = 42.7 bits (99), Expect = 5e-04
Identities = 67/302 (22%), Positives = 107/302 (35%), Gaps = 41/302 (13%)
Query: 13 TTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGN 72
T+A LF+ G+ ++ F +++ TV++GE+AT C + V W L+
Sbjct: 11563 TSARLFVTGIRLK-----FMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTS- 11616
Query: 73 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 132
R +++ + + + ++ V + D V+ + +V ++ P
Sbjct: 11617 -------RTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKV---LEADPYFT 11666
Query: 133 NISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEI 182
D T E +TL C + + P V W K+G+ V +Y L+I
Sbjct: 11667 VKLHDKTAVEKDEITLKC-EVSKDVP-VKW----FKDGEEIVPSPKYSIKADGLRRILKI 11720
Query: 183 SDIKRDQSGEYECSALND--VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 240
GEY C D A V I V P Y V VG+ E S
Sbjct: 11721 KKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLY-----GVEVFVGETAHFEIELS 11775
Query: 241 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
P QW + L D IE+ G+ L N G + A N N
Sbjct: 11776 E-PDVHGQWKLKGQPLTASPDCEIIED-GKKHILILHNCQLGMTGEVSFQAANAKSAANL 11833
Query: 301 SI 302
+
Sbjct: 11834 KV 11835
Score = 41.6 bits (96), Expect = 0.001
Identities = 58/259 (22%), Positives = 98/259 (37%), Gaps = 28/259 (10%)
Query: 43 GESATLRCTIDDRVTRVAWL-NRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVY 101
G SA C + W+ + S I + ++ D + + I +V +
Sbjct: 11133 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGK---------DRKLHIIDVQLS 11183
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQ--IMNISSDITVNEGSSVTLLCLAIGRPEPT 159
D G YTC ++ N KTS L+V+ P + + ++TV +G + L C E
Sbjct: 11184 DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERD 11241
Query: 160 VTWRH----LSVKEGQ---GFVSEDEYLEISDIKRDQSGEYEC---SALNDVAAPDVRKV 209
V WR + K G+ G + L I+D +G Y +A N + V+ V
Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301
Query: 210 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENK 268
++ ++ + ++ V I +C+ A +WFK + A D I
Sbjct: 11302 EVIRDW--LVKPIRDQHVKPKGTAIFACDI-AKDTPNIKWFKGYDEIPAEPNDKTEILRD 11358
Query: 269 GRMSTLTFFNVSEKDYGNY 287
G L N +D Y
Sbjct: 11359 GNHLYLKIKNAMPEDIAEY 11377
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 13/124 (10%)
Query: 128 PPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS----VKEGQ-GFVSEDEY 179
PP+I ++ + V G + L + GRP P VTWR + V++GQ V +
Sbjct: 18603 PPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF 18662
Query: 180 LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEA 239
L I + RD SG+Y + +N V ++ P +S K + V+ SC
Sbjct: 18663 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTK-----TSCHV 18717
Query: 240 SAVP 243
S P
Sbjct: 18718 SWAP 18721
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 16/101 (15%)
Query: 127 VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR----------HLSVKEGQGFVSE 176
+PP+I+ + IT+ G + + G+P PT W+ HL+V +
Sbjct: 18898 LPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK----ADS 18952
Query: 177 DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
L I D+ R SG Y +A N + D +K+K+ V P
Sbjct: 18953 SSILIIKDVTRKDSGYYSLTAENS-SGTDTQKIKVVVMDAP 18992
Score = 40.8 bits (94), Expect = 0.002
Identities = 55/287 (19%), Positives = 113/287 (39%), Gaps = 33/287 (11%)
Query: 40 VRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
+ +G++ C I + + W + N SI V I + YS+ I+N
Sbjct: 33145 INEGQNVLFTCEISGEPSPEIEW-------FKNNLPISISSNVSIS-RSRNVYSLEIRNA 33196
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHL----IVQVPPQ--IMNISSDITVNEGSSVTLLCLA 152
V D G YT + ++ L +V+ P + ++ S D ++ S + ++
Sbjct: 33197 SVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMS 33256
Query: 153 IGRPEPT-----------VTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 201
+ E + +T + Q S E S ++ S S + +
Sbjct: 33257 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQE----SFVEMSSSSFMGISNMTQL 33312
Query: 202 AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILS--CEASAVPMAEFQWFKEETRLATG 259
+ + +K + P +A + +S+ + +L+ C + P E W ++ +
Sbjct: 33313 ESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 33372
Query: 260 LDG-MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
G IEN ++TL +V ++D G YT N+ G+ +A++ ++
Sbjct: 33373 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 33419
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/182 (24%), Positives = 71/182 (39%), Gaps = 16/182 (8%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
TF + + +V V +G +AT I V V+W ++ S P V I +
Sbjct: 7 TFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVIST-----STLPGVQISFSDG 61
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV---PPQIMNISSDITVNEGSS 145
+ + I V + G Y+ + TS L+V+ PP + +TV +GS
Sbjct: 62 -RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ 120
Query: 146 VTLLCLAIGRPEPTVTWRH--LSVKEGQGFVSEDE----YLEISDIKRDQSGEYECSALN 199
V L G P P V + ++ F E L I++ + SG Y +A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 200 DV 201
V
Sbjct: 181 SV 182
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 27/175 (15%)
Query: 142 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRD------------- 188
EG + +GRP P W H +GQ V++ Y IK D
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFH----DGQQIVND--YTHKVVIKEDGTQSLIIVPATPS 1523
Query: 189 QSGEYECSALNDVAAPDVRKVKITVNY------PPYISKAKNTGVSVGQKGILSCEASAV 242
SGE+ A N + V +TV P ++ K KN + G + + A+
Sbjct: 1524 DSGEWTVVAQNRAGRSSI-SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGN 1582
Query: 243 PMAEFQWFKEETRLAT-GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
P + W K + +RIE + L + +D YT A NK G
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637
Score = 40.0 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 109 SVQTDNHPKTSRVHLIVQVPPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRH- 164
++ + P L VPP+I + + S +TV G++V L G+P PTV+W+
Sbjct: 19273 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 19332
Query: 165 ---LSVKEGQGFVSEDEY--LEISDIKRDQSGEYECSALN 199
L EG + LE+ + R SG+Y +A N
Sbjct: 19333 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 19372
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/140 (22%), Positives = 60/140 (42%), Gaps = 16/140 (11%)
Query: 182 ISDIKRDQSGEYECSALNDVAAPD----VRKVKITVNYPPYIS-----KAKNTGVSVGQK 232
+ ++ Q E+ A+N++ + + V PP I + V G+
Sbjct: 15356 VENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEP 15415
Query: 233 GILSCEASAVPMAEFQWFKEETRLATGLDGMRI--ENKGRMSTLTFFNVSE---KDYGNY 287
+ + + +PM + +W K ET + D ++I E R T ++ + +D G Y
Sbjct: 15416 VHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTY 15475
Query: 288 TCVATNKLGNT--NASITLY 305
T A+N+LG+ N + +Y
Sbjct: 15476 TVTASNRLGSVFRNVHVEVY 15495
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 15/174 (8%)
Query: 134 ISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEIS 183
+ + + G V +L GRP PTVTWR K+ + S+ Y L I
Sbjct: 27277 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWR----KDEKNLGSDARYSIENTDSSSLLTIP 27332
Query: 184 DIKRDQSGEYECSALNDVAAPDVRKVKITV-NYPPYISKAKNTGVSVGQKGILSCEASAV 242
+ R+ +G+Y + N V P V + V + P K + VS G +L
Sbjct: 27333 QVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLID 27392
Query: 243 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ + E R AT + +K ++ ++SEK + +A N++G
Sbjct: 27393 GGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG 27446
Score = 38.1 bits (87), Expect = 0.011
Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 20/173 (11%)
Query: 30 TFPKAMDNVTVRQGES-ATLRCTIDDRVTRVAWLNRSTILYAGNDKWSI--DPRVIILVN 86
TF + + +V ++ ++ AT C + +V W ++ G DK+ + D +V
Sbjct: 2175 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG-DKYRMHSDRKV----- 2228
Query: 87 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 146
+ + I +D D Y+C + D + KT+ ++ + + DI V E S
Sbjct: 2229 ----HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSG 2284
Query: 147 TLLCLAIGRPEPTVTWRHLSVK---EGQGFVSE---DEYLEISDIKRDQSGEY 193
L C+ + W H V+ G+ ++ + L + D+ ++ GEY
Sbjct: 2285 ELECI-VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 17/85 (20%)
Query: 128 PPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----- 179
PP++ + ITV G ++ +L GRPEP +TW KEG+ V E
Sbjct: 17905 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW----TKEGKVLVREKRVDLIQD 17960
Query: 180 -----LEISDIKRDQSGEYECSALN 199
L+I + R G+Y SA N
Sbjct: 17961 LPRVELQIKEAVRADHGKYIISAKN 17985
Score = 38.1 bits (87), Expect = 0.011
Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 4/115 (3%)
Query: 191 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWF 250
GE E S +++ P K + + P + + +N V L C+ + P +W+
Sbjct: 30906 GESEWSEISEPITP---KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWY 30962
Query: 251 KE-ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++ + +A GL E KG L +V++ D Y ATN+ G+ + + +L
Sbjct: 30963 RQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASL 31017
Score = 38.1 bits (87), Expect = 0.011
Identities = 59/297 (19%), Positives = 106/297 (35%), Gaps = 73/297 (24%)
Query: 30 TFPKAMDNVTVRQGESATLRCTID-DRVTRVAWLNRSTILYAG------NDKWSIDPRVI 82
T P++M TV +GESA C D + V V WL + +L K+ +
Sbjct: 32565 TKPRSM---TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 32621
Query: 83 -ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN 141
+ + YS++++N + E +T ++Q K V PP++ +
Sbjct: 32622 SVQASDEGNYSVVVENSEGKQEAEFTLTIQ-----KARVTEKAVTSPPRVKS-------- 32668
Query: 142 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 201
PEP V S + +K + + + +
Sbjct: 32669 --------------PEPRVK-------------SPEAVKSPKRVKSPEPSHPKAVSPTET 32701
Query: 202 AAPDVRKVK-ITVNYPPYISKAKNTGVSVGQKGILSC--EASAVPMAEFQWFKEETRLAT 258
KV+ + V+ PP I++ S + L+C E+S + E W+K
Sbjct: 32702 KPTPTEKVQHLPVSAPPKITQFLKAEAS-KEIAKLTCVVESSVLRAKEVTWYK------- 32753
Query: 259 GLDGMRIENKGRMS---------TLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG 306
DG +++ G L N++E D G Y C + + G + ++ G
Sbjct: 32754 --DGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 32808
Score = 36.6 bits (83), Expect = 0.033
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 58/312 (18%)
Query: 4 PAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLN 63
P Y V T L + P P+R G + ++ RQG +RC D V+
Sbjct: 27861 PDYIDVTRETITLKWNP--PLRDGGSKIVGY--SIEKRQGNERWVRCNFTD----VSECQ 27912
Query: 64 RSTILYAGNDKWS---IDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 120
+ + D++ I + ++ P+Q S +I D +N P
Sbjct: 27913 YTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRD-------------ENVPP--- 27956
Query: 121 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----------RHLSVKEG 170
IV+ P+ + + + G S+ + L GRP P VTW ++ + +
Sbjct: 27957 ---IVEFGPEYFD---GLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDV 28010
Query: 171 QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVKITVNYPPYISKAKNTGVSV 229
G S L + D RD G Y A N + KVK+ + + T ++
Sbjct: 28011 LGSTS----LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNIT- 28065
Query: 230 GQKGILSCEA----SAVPMAEFQWFKEET-RLATGLDGMRIENKGRMSTLTFFNVSEKDY 284
G+K L +A P+ + K ET RLA L IE+K + T + +
Sbjct: 28066 GEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL----IEDKCEAQSYTAIKLINGNE 28121
Query: 285 GNYTCVATNKLG 296
+ A NK G
Sbjct: 28122 YQFRVSAVNKFG 28133
Score = 36.2 bits (82), Expect = 0.043
Identities = 42/206 (20%), Positives = 64/206 (31%), Gaps = 50/206 (24%)
Query: 44 ESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDE 103
E A L C ++ V R + Y K + + Y + I N+ D+
Sbjct: 32731 EIAKLTCVVESSVLRA----KEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQ 32786
Query: 104 GPYTCSVQTDN-----------------HPKTSRVHLI---------------------- 124
G Y C + + H K S++
Sbjct: 32787 GEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPE 32846
Query: 125 -VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR---HLSVKEGQGFVSEDE-- 178
+ P I+ D TV+ S A G P PT W + G+ +SED+
Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGG 32906
Query: 179 -YLEISDIKRDQSGEYECSALNDVAA 203
+LEI SG Y C+ N +
Sbjct: 32907 FFLEIHKTDTSDSGLYTCTVKNSAGS 32932
Score = 35.8 bits (81), Expect = 0.056
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 220 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD-GMRIENKGRMSTLTFFN 278
S+ KN + G C+ S P+ + W+K+ R+ G M GR S L
Sbjct: 1295 SRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS-LRIPV 1353
Query: 279 VSEKDYGNYTCVATNKLGNTNASITLY 305
V +D G YT A+N GN S LY
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSGKLY 1380
Score = 35.4 bits (80), Expect = 0.073
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 243 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
P+ W KEE L D + I+N G S L + KD+G Y ATN G+ A+
Sbjct: 15132 PVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 15189
Query: 303 TLY---GPGAVID 312
+ PG V+D
Sbjct: 15190 RVEVFDVPGPVLD 15202
Score = 35.0 bits (79), Expect = 0.096
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 126 QVPPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVSED--- 177
Q P+I + + + +TV G+ + L G+PEP +TW + +K+ + E+
Sbjct: 13685 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 13744
Query: 178 -EYLEISDIKRDQSGEYECSALN 199
+ I D KR +G Y A+N
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVN 13767
Score = 34.7 bits (78), Expect = 0.12
Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 19/141 (13%)
Query: 71 GNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD---NHPKTSRVHLIVQ- 126
G+DKW+ V + T T +IQ +E + S Q + + P+ V +I +
Sbjct: 22091 GSDKWATCATVKVTEATITG---LIQG----EEYSFRVSAQNEKGISDPRQLSVPVIAKD 22143
Query: 127 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSV------KEGQGFVSEDE 178
+PP + + TV G + + IGRP P VTW +V + +
Sbjct: 22144 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNS 22203
Query: 179 YLEISDIKRDQSGEYECSALN 199
L I D R+ G Y N
Sbjct: 22204 LLTIKDACREDVGHYVVKLTN 22224
Score = 34.7 bits (78), Expect = 0.12
Identities = 34/158 (21%), Positives = 64/158 (40%), Gaps = 21/158 (13%)
Query: 72 NDKWSIDPRV----IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ- 126
++KWS RV ++ N + + V V ++G + P++ V ++ +
Sbjct: 23174 SEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGR--------SDPRSLAVPIVAKD 23225
Query: 127 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRH--LSVKEGQGFVSEDEY--- 179
+ P + S +V G + + GRP+PT+TW L +K+ D
Sbjct: 23226 LVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 23285
Query: 180 -LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 216
L I + +D G+Y + N V +T++ P
Sbjct: 23286 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323
Score = 33.9 bits (76), Expect = 0.21
Identities = 38/181 (20%), Positives = 62/181 (34%), Gaps = 17/181 (9%)
Query: 151 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV-RKV 209
+A G P ++EG+ + + L + E A++ AP++ V
Sbjct: 13635 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDV 13694
Query: 210 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 269
K+ V G K L + P + W K + L + IEN
Sbjct: 13695 KLLAGLT----------VKAGTKIELPATVTGKPEPKITWTKADMILKQD-KRITIENVP 13743
Query: 270 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY-----GPGAVIDGVNSASRALACL 324
+ ST+T + D G Y A N G A + + GP A D + + +
Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 13803
Query: 325 W 325
W
Sbjct: 13804 W 13804
Score = 33.5 bits (75), Expect = 0.28
Identities = 54/289 (18%), Positives = 94/289 (32%), Gaps = 68/289 (23%)
Query: 83 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV-----QVPPQIMNISSD 137
+++ S++I D G +T Q + V L V QV P + +
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKN 1564
Query: 138 ITVNEGSSVTLLCLAIGRPEPTVTW--------RHLSVKEGQGFVSEDEYLEISDIKRDQ 189
+ + EGS + + A G P P + W H K + L+I
Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624
Query: 190 SGEYECSALN------------------------------------DVAAPDVRKVKITV 213
S Y +A+N ++AAP++ + +
Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684
Query: 214 NYPPY--------------ISKAKNTGVSVGQKGILSCEASAVPMAE----FQWFKEETR 255
+ K K T + + + G E P+ + +W +
Sbjct: 1685 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L + +R+ N+ +L + +D G TC ATNK G + S TL
Sbjct: 1745 LEAA-NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792
Score = 33.5 bits (75), Expect = 0.28
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 129 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW---RHLSVKEGQGFVSED--EYLEIS 183
P I+ + V EG + C G P+P V W L K + V D YL+I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIV 1900
Query: 184 DIKRDQSGEYECSALNDVAAPDVRKVKITV 213
D K +GE + +A N + KVK+ +
Sbjct: 1901 DCKSYDTGEVKVTAENPEGVIE-HKVKLEI 1929
Score = 33.5 bits (75), Expect = 0.28
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 23/109 (21%)
Query: 130 QIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF-------VSEDEY--- 179
+I+ +TV EG S C G P PTVTW +++GQ V+ +Y
Sbjct: 32562 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTW----LRKGQVLSTSARHQVTTTKYKST 32617
Query: 180 LEISDIKRDQSGEYECSALNDVAAPD------VRKVKIT---VNYPPYI 219
EIS ++ G Y N + ++K ++T V PP +
Sbjct: 32618 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 32666
Score = 33.1 bits (74), Expect = 0.36
Identities = 53/279 (18%), Positives = 103/279 (36%), Gaps = 31/279 (11%)
Query: 33 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS 92
K +VT + + ++ V W ++S + + + R + +
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKV--------HK 2850
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+M+QN+ D G YT V + L V+ I +I V E + + C
Sbjct: 2851 LMLQNISPSDAGEYTAVV----GQLECKAKLFVET-LHITKTMKNIEVPETKTASFECEV 2905
Query: 153 IGRPEPTVTWRH---LSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSALNDVAAPDVR 207
P++ ++ + + E V + + L I + + S EY ND
Sbjct: 2906 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND------- 2958
Query: 208 KVKITVNYPPYISKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATGLDGMRIE 266
+V T+ P + + ++ +K ++ E + ++W K + + D ++
Sbjct: 2959 QVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKS-TDKCQMR 3017
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
K +L NV D +YT VA G ++ TLY
Sbjct: 3018 TKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLY 3052
Score = 33.1 bits (74), Expect = 0.36
Identities = 29/134 (21%), Positives = 50/134 (37%), Gaps = 6/134 (4%)
Query: 174 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN-----YPPYISKAKNTGVS 228
V +D L ++ +K + ++ +A N V R+ + PP I + +
Sbjct: 18852 VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIK 18911
Query: 229 VGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYT 288
G+K + P +W K E + T + + S L +V+ KD G Y+
Sbjct: 18912 AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVHKADSSSILIIKDVTRKDSGYYS 18970
Query: 289 CVATNKLGNTNASI 302
A N G I
Sbjct: 18971 LTAENSSGTDTQKI 18984
Score = 32.7 bits (73), Expect = 0.47
Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 26/135 (19%)
Query: 38 VTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI- 95
VT+R G S L ++ R V W K ID +++T YS++I
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITW-----------SKQGIDLASRAIIDTTESYSLLIV 29504
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
V+ YD G YT + + K++ V + V P G ++ + R
Sbjct: 29505 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP-------------GPCPSVKVKEVSR 29551
Query: 156 PEPTVTWRHLSVKEG 170
T+TW ++ G
Sbjct: 29552 DSVTITWEIPTIDGG 29566
Score = 32.7 bits (73), Expect = 0.47
Identities = 43/205 (20%), Positives = 73/205 (35%), Gaps = 16/205 (7%)
Query: 114 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEG 170
+ P T + + +Q P ++ V S+ TL+C G P+P V W + +G
Sbjct: 30914 SEPITPKSDVPIQAP-HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADG 30972
Query: 171 -----QGFVSEDEYLEISDIKRDQSGEYECSALND------VAAPDVRKVKITVNYPPYI 219
Q F L I+ + D + Y+ A N A+ +V +V ++ P +
Sbjct: 30973 LKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTL 31031
Query: 220 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 279
G+ + S P W K + + I + S + V
Sbjct: 31032 EGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGV 31091
Query: 280 SEKDYGNYTCVATNKLGNTNASITL 304
KD G Y A N+ G ++ L
Sbjct: 31092 ERKDAGFYVVCAKNRFGIDQKTVEL 31116
Score = 32.3 bits (72), Expect = 0.62
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 12/125 (9%)
Query: 182 ISDIKRDQSGEYECSALNDVAA--PDVRKVKITVN---YPP--YISKAKNTGVSVGQKGI 234
+ +K + EY SA+N V P IT PP ++ + VG+
Sbjct: 16778 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFA 16837
Query: 235 LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK--DYGNYTCVAT 292
L+ S P + WFK+E A L+ R K +TL + K D G Y V
Sbjct: 16838 LTGRYSGKPKPKVSWFKDE---ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVE 16894
Query: 293 NKLGN 297
N G+
Sbjct: 16895 NSTGS 16899
Score = 32.3 bits (72), Expect = 0.62
Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 12/132 (9%)
Query: 182 ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEAS 240
++D++ + ++ SA+N D +V T+ ++ + + + Q ++ AS
Sbjct: 28315 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGAS 28374
Query: 241 AVPMAEFQ--------WFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVAT 292
+Q W K ++ L+ D I STLT N + D G YT
Sbjct: 28375 IRLFIAYQGRPTPTAVWSKPDSNLSLRAD---IHTTDSFSTLTVENCNRNDAGKYTLTVE 28431
Query: 293 NKLGNTNASITL 304
N G+ + + T+
Sbjct: 28432 NNSGSKSITFTV 28443
Score = 32.3 bits (72), Expect = 0.62
Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 133 NISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRD 188
++ +T+ G+S+ L+ GRP P +TW + + + L + + R
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 29510
Query: 189 QSGEYECSALN 199
+G+Y A N
Sbjct: 29511 DAGKYTIEAEN 29521
Score = 32.0 bits (71), Expect = 0.81
Identities = 47/217 (21%), Positives = 85/217 (39%), Gaps = 18/217 (8%)
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 150
+ + I D D G YTC+V+ +S L ++ + ++ + S +T
Sbjct: 32907 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD--TEAQKVSTQKTSEITPQK 32964
Query: 151 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK-- 208
A+ + E ++ + L +E + +SE + E +K + S + AA + K
Sbjct: 32965 KAVVQEE--ISQKALRSEEIK--MSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI 33020
Query: 209 VKITVNYPPYIS---------KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
V + S KA +T +S+ + L +A+ + +W L T
Sbjct: 33021 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVEL-TN 33079
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ R G TLT S +D G TC++ K G
Sbjct: 33080 SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG 33116
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/89 (21%), Positives = 35/89 (39%)
Query: 216 PPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLT 275
P ++ K + GQ + PM E WF + ++ + + +L
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 276 FFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ D G +T VA N+ G ++ S+ L
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVIL 1545
Score = 31.6 bits (70), Expect = 1.1
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 138 ITVNEGSSVTLLCLAIGRPEPTVTWRH----LSVKEGQGF--VSEDEYLEISDIKRDQSG 191
+ G ++ + +GRP+PTVTW+ L + F + L I++ R SG
Sbjct: 21075 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSG 21134
Query: 192 EYECSALNDV 201
Y +A N V
Sbjct: 21135 PYPLTARNIV 21144
Score = 31.2 bits (69), Expect = 1.4
Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 23/155 (14%)
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLIV--------QVPPQIMNISSDITVNEGSSVTLLC 150
D+ + G Y V+ N S+ V +PP I ++ + V EG++V ++
Sbjct: 16080 DLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI-DLKEFMEVEEGTNVNIVA 16138
Query: 151 LAIGRPEPTVTWRHLSVKEGQG-------------FVSEDEYLEISDIKRDQSGEYECSA 197
G P PT+TW K+ V + L I +R +G Y +A
Sbjct: 16139 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 16198
Query: 198 LNDV-AAPDVRKVKITVNYPPYISKAKNTGVSVGQ 231
+N++ A ++ + P + K VS Q
Sbjct: 16199 VNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ 16233
Score = 30.8 bits (68), Expect = 1.8
Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 4/78 (5%)
Query: 133 NISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRD 188
N V G+S+ L GRP PT W +LS++ L + + R+
Sbjct: 28362 NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421
Query: 189 QSGEYECSALNDVAAPDV 206
+G+Y + N+ + +
Sbjct: 28422 DAGKYTLTVENNSGSKSI 28439
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 2/94 (2%)
Query: 212 TVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGR 270
T+++ P I+ + ++ V GQ + P AE +W+ L + N
Sbjct: 32369 TLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQES-SKIHYTNTSG 32427
Query: 271 MSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ TL + D G Y V TN G + TL
Sbjct: 32428 VLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 32461
Score = 30.4 bits (67), Expect = 2.4
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 230 GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 289
G+K + AVP+ W K+ + D + ++N + L D G YT
Sbjct: 14401 GEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRLTMKNDHISAHLEVPKSVRADAGIYTI 14459
Query: 290 VATNKLGNTNASITL 304
NKLG+ ASI +
Sbjct: 14460 TLENKLGSATASINV 14474
Score = 30.4 bits (67), Expect = 2.4
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 14/71 (19%)
Query: 143 GSSVTLLCLAIGRPEPTVTWR-----HLSVKEGQGFVSEDEYLE---------ISDIKRD 188
GS + + + GRP P +W ++K+G + ED LE I + KR
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 189 QSGEYECSALN 199
+G+Y +A N
Sbjct: 15885 HTGKYSITAKN 15895
Score = 30.0 bits (66), Expect = 3.1
Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 133 NISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRD 188
++ I V+ G + ++ G+P PTVTW R L + + + I + +R
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS 16588
Query: 189 QSGEYECSALND 200
G Y A N+
Sbjct: 16589 HQGVYSLLAKNE 16600
Score = 30.0 bits (66), Expect = 3.1
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 38 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
+ +R G S L I R T V W G I II V T + S+++
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKW---------GKVDGEIRDAAIIDV-TSSFTSLVLD 23001
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHL-IVQVPPQIMNISSDITVNEGSSVT 147
NV+ YD G YT +++ + K++ V + ++ P +N+ + S+T
Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 23053
Score = 30.0 bits (66), Expect = 3.1
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 27/145 (18%)
Query: 71 GNDKWSI--DPRVIILVNTPTQYSIMIQ-NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ- 126
G +KWSI + +V V T Q V Y+E + + P+ V +I +
Sbjct: 24255 GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE-------KGKSDPRVLGVPVIAKD 24307
Query: 127 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF----------V 174
+ P + + ++ G + + IGRP P ++W VK+G+
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISW----VKDGEPLKQTTRVNVEET 24363
Query: 175 SEDEYLEISDIKRDQSGEYECSALN 199
+ L I + +D G+Y +A N
Sbjct: 24364 ATSTVLHIKEGNKDDFGKYTVTATN 24388
Score = 29.6 bits (65), Expect = 4.0
Identities = 24/129 (18%), Positives = 47/129 (36%), Gaps = 7/129 (5%)
Query: 182 ISDIKRDQSGEYECSALNDVAAPDVRKVKITV-----NYPPYISKAKNT-GVSVGQKGIL 235
++ + Q ++ A N+ D R + + V P + NT + G+ +
Sbjct: 24272 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKI 24331
Query: 236 SCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 295
P W K+ L + +E + L ++ D+G YT ATN
Sbjct: 24332 EIPVIGRPRPNISWVKDGEPLKQ-TTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSA 24390
Query: 296 GNTNASITL 304
G ++++
Sbjct: 24391 GTATENLSV 24399
Score = 29.6 bits (65), Expect = 4.0
Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 16/125 (12%)
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP---------QIMNISSDITVN 141
Y + I +V D+ YT + + + L V + P + ++
Sbjct: 31748 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQ 31807
Query: 142 EGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSE--DEY-LEISDIKRDQSGEYE 194
EG SV G P PT+ W + LS+ + E D Y L I D + +G Y
Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 31867
Query: 195 CSALN 199
+A N
Sbjct: 31868 VTATN 31872
Score = 29.3 bits (64), Expect = 5.2
Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 12/131 (9%)
Query: 181 EISDIKRDQSGEYECSALNDVA------APDVRKVKITVNYPPYI---SKAKNTGVSVGQ 231
+++ ++ Q+ ++ A+N P+ VK + P I + A+ + VG
Sbjct: 17175 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGD 17234
Query: 232 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
LS VP + W KE+ T RI+ S L N + +D G Y+
Sbjct: 17235 TLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDVTPVGSKLEIRNAAHEDGGIYSLTV 17291
Query: 292 TNKLGNTNASI 302
N G+ S+
Sbjct: 17292 ENPAGSKTVSV 17302
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 3/130 (2%)
Query: 176 EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT-GVSVGQKGI 234
ED+ E I R+ +G + S +D + + +I K K+ V G+ +
Sbjct: 24669 EDQRYEFRVIARNAAGNF--SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFV 24726
Query: 235 LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNK 294
L + P+ + W K+ L M I++ + +TL + D G Y +N
Sbjct: 24727 LEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV 24786
Query: 295 LGNTNASITL 304
G + IT+
Sbjct: 24787 GGTKSIPITV 24796
Score = 29.3 bits (64), Expect = 5.2
Identities = 33/147 (22%), Positives = 56/147 (38%), Gaps = 31/147 (21%)
Query: 176 EDEYLEISDIKRDQSGEYECSALNDVAAPDVRK---------VKITVNYPPYISKAKNTG 226
++ Y E++++ DQ E+ A N AA V + VK V P + K
Sbjct: 25740 QETYFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797
Query: 227 VSVGQKG---ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM--------STLT 275
V V + G ++ + + P+ W K DG+ IE + R + LT
Sbjct: 25798 VIVVKAGEVLKINADIAGRPLPVISWAK---------DGIEIEERARTEIISTDNHTLLT 25848
Query: 276 FFNVSEKDYGNYTCVATNKLGNTNASI 302
+ +D G Y N G + ++
Sbjct: 25849 VKDCIRRDTGQYVLTLKNVAGTRSVAV 25875
Score = 28.9 bits (63), Expect = 6.8
Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 13/95 (13%)
Query: 13 TTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGN 72
T+A L I P++ F K + N+ V + +SAT C + V W T L +
Sbjct: 8823 TSAELRIEAEPIQ-----FTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTEL-TES 8876
Query: 73 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYT 107
K++ N + + I NV DEG Y+
Sbjct: 8877 QKYNFR-------NDGRCHYMTIHNVTPDDEGVYS 8904
Score = 28.9 bits (63), Expect = 6.8
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 243 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
P E +W K + + D I+ ++L NV+ D G YT N G +A +
Sbjct: 22970 PTPEVKWGKVDGEIR---DAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 23026
Query: 303 TL 304
T+
Sbjct: 23027 TV 23028
Score = 28.9 bits (63), Expect = 6.8
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 138 ITVNEGSSVTLLCLAIGRPEPTVTWR--HLSVKEGQGF----VSEDEYLEISDIKRDQSG 191
IT GS T+ GRP P VTW+ + +KE + L + D R SG
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716
Query: 192 EYECSALNDVAAPDVRKVKITVNYP 216
Y + N + + P
Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIGRP 28741
Score = 28.5 bits (62), Expect = 8.9
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 8/88 (9%)
Query: 136 SDITVNEGSSVTLLCLAIGRPEPTVTWRH--LSVKEGQGFV--SEDE---YLEISDIKRD 188
+ +TV G +V L G+P+P+++W L +KE + FV S+ E L I + K++
Sbjct: 27571 AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE-FVRFSKTENKITLSIKNAKKE 27629
Query: 189 QSGEYECSALNDVAAPDVRKVKITVNYP 216
G+Y N V V IT+ P
Sbjct: 27630 HGGKYTVILDNAVCRIAVPITVITLGPP 27657
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 95.9 bits (237), Expect = 5e-20
Identities = 63/216 (29%), Positives = 95/216 (43%), Gaps = 15/216 (6%)
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
T + +QN+ D G +TC + + ++IVQ PPQ D V E +V
Sbjct: 379 TSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEW 438
Query: 149 LCLAIGRPEPTVTWRHLSVK---EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
LC A G P P + W + EGQ V L I + G+YEC A++ +
Sbjct: 439 LCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG--- 495
Query: 206 VRKVKITVNYPP-----YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
V+KV + + P + ++T V VG+ +SC A P W KE ++ T
Sbjct: 496 VKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQI-TES 554
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
++++G TLT ++ D G Y CVA N G
Sbjct: 555 GKFHVDDEG---TLTIYDAGFPDQGRYECVARNSFG 587
Score = 63.2 bits (152), Expect = 3e-10
Identities = 73/290 (25%), Positives = 109/290 (37%), Gaps = 23/290 (7%)
Query: 33 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS--TILYAGNDK----W-----SIDPRV 81
+A+ +VTV + + R T + + V N T GN K W S+D
Sbjct: 219 RAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLED 278
Query: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD-NHPKTSRVHL---IVQVPPQIMNISSD 137
+N ++MI+N D+G Y C + KT L + P + D
Sbjct: 279 DTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQD 338
Query: 138 ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKE--GQGFVSEDEYLEISDIKRDQSGEYEC 195
V G+S TL C+A G P P +TW + E G V+ L + +I + G + C
Sbjct: 339 TEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTC 398
Query: 196 SALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEET 254
A N I V PP + V + + + CEA P W K
Sbjct: 399 HANNSHGTVQA-AANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGG 457
Query: 255 RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+L ++G TL ++ D G Y C A + LG S+ L
Sbjct: 458 QLP--VEGQHTVLSS--GTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 95.5 bits (236), Expect = 6e-20
Identities = 76/272 (27%), Positives = 113/272 (41%), Gaps = 25/272 (9%)
Query: 43 GESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVY 101
G S C + DR T++ W L G+ S+ V+ IQN+D
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEGGQLPPGH---SVQDGVL-----------RIQNLDQS 3459
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM-NISSDI-TVNEGSSVTLLCLAIGRPEPT 159
+G Y C + L++Q P ++ NI + + TV G +V CLA+G P+P
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQ 3519
Query: 160 VTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI 219
VTW + G V + I+ ++ +G+Y C+A N A V + V P I
Sbjct: 3520 VTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATN-AAGTTQSHVLLLVQALPQI 3578
Query: 220 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 279
S + V G + C AS P + W K + L R+EN + L +V
Sbjct: 3579 SMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP---PDSRLEN----NMLMLPSV 3631
Query: 280 SEKDYGNYTCVATNKLGNTNASITLYGPGAVI 311
+D G Y C ATN+ G A L P V+
Sbjct: 3632 RPQDAGTYVCTATNRQGKVKAFAHLQVPERVV 3663
Score = 83.2 bits (204), Expect = 3e-16
Identities = 62/224 (27%), Positives = 94/224 (41%), Gaps = 17/224 (7%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV------PPQIMNISSDITVNEGSSV 146
+ I + D G Y C Q +V +IV PQ+ +++TV G +
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229
Query: 147 TLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
TL C A G P PT+ W L E + L I + + SG+Y C+A + +
Sbjct: 3230 TLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEA 3289
Query: 207 RKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 265
+ + V PPY + ++ V G+ L C A P FQW +R+ + L G
Sbjct: 3290 -TIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQW----SRVGSSLPG--- 3341
Query: 266 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGP 307
R L F + +D G Y C TNK+G+ A + + GP
Sbjct: 3342 RATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP 3385
Score = 79.7 bits (195), Expect = 3e-15
Identities = 71/283 (25%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 39 TVRQGESATLRCTIDDRVTRVA--WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
TV+QG+ A+ +C I D ++ W R+ L D I P I+ T+ S
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLEWKTRNQEL---EDNVHISPNGSIITIVGTRPS---- 3084
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI-SSDITVNEGSSVTLLCLAIGR 155
+ G Y C S V+L V PP + + + V G +VTL C++ G
Sbjct: 3085 -----NHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGE 3139
Query: 156 PEPTVTWRHLSVKEGQ------GFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 209
P + W +S + G + L+IS K +G Y C A N + ++V
Sbjct: 3140 PRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQ-KQV 3198
Query: 210 KITVN-------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
++ V+ P ++ V G L C A+ P W K + L
Sbjct: 3199 EVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPW---- 3254
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 305
+++ TL V+++D G Y C AT+ G+ A+I L+
Sbjct: 3255 ---QHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILH 3294
Score = 62.4 bits (150), Expect = 6e-10
Identities = 79/331 (23%), Positives = 123/331 (37%), Gaps = 52/331 (15%)
Query: 12 ATTALLFIPGVPVRSGDATFPKAM---DNVTVRQGESATLRCTIDDRV-TRVAWLNRSTI 67
A TA I V + + DA+ P + +V +G++ L C + +V W R
Sbjct: 2031 AGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGG- 2089
Query: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV-- 125
S+ P + + + + V D G Y C V+ + PK + + + V
Sbjct: 2090 --------SLPPHTQVHGSR-----LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLH 2136
Query: 126 ---------QVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 173
VP I S V EG ++ L C+ G+ VTW
Sbjct: 2137 GTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH 2196
Query: 174 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN-------YPPYISKAKNTG 226
+ L + + SGEY C + + P V +T+ PP ++ ++
Sbjct: 2197 QTHGSLLRLHQVTPADSGEYVCHVVG-TSGPLEASVLVTIEASVIPGPIPPVRIESSSST 2255
Query: 227 VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGN 286
V+ GQ LSC + A+ W+K L ++ R S L F S D G
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA-------RHQVRGSRLYIFQASPADAGQ 2308
Query: 287 YTCVATNKLGNTNASITLYGPGAVIDGVNSA 317
Y C A+N + ASIT+ G G N A
Sbjct: 2309 YVCRASNGM---EASITVTVTGT--QGANLA 2334
Score = 62.4 bits (150), Expect = 6e-10
Identities = 64/282 (22%), Positives = 99/282 (35%), Gaps = 36/282 (12%)
Query: 38 VTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 97
+TV G +ATLRC+ +T A WS + + +++I
Sbjct: 3221 LTVEAGHTATLRCS-------------ATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPR 3267
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 157
V D G Y C+ + + + L V+ PP + +V G +V L CLA G P
Sbjct: 3268 VAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPP 3327
Query: 158 PTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
T W + + +E L + SG Y C N V + + ++ V PP
Sbjct: 3328 LTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEA-FAQLLVQGPP 3386
Query: 218 YISKAKNTGV---------------SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
A + S+G C + + +WFKE +L G
Sbjct: 3387 GSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--- 3443
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ + L N+ + G Y C A G AS L
Sbjct: 3444 ----HSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQL 3481
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/229 (24%), Positives = 88/229 (38%), Gaps = 26/229 (11%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---------VPPQIMNISSDITVNEG 143
+ I V D G Y C V + + + + +Q V P I SS TV EG
Sbjct: 2585 LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEG 2644
Query: 144 SSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA 203
++ L C+ +P+ +TW + +L + + SGEY C A N++ A
Sbjct: 2645 QTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDA 2704
Query: 204 PD---VRKVKITVNYP-------PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 253
+ V V + P P ++ ++ V+ G+ L+C A+ W K
Sbjct: 2705 LEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRG 2764
Query: 254 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
L + ++ R S L +VS D G Y C G AS+
Sbjct: 2765 GSLPS-------HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASV 2806
Score = 54.7 bits (130), Expect = 1e-07
Identities = 71/296 (23%), Positives = 113/296 (38%), Gaps = 47/296 (15%)
Query: 38 VTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 97
+TV+ G+ A RC+ T T+ + G + + I + +
Sbjct: 1875 LTVQPGQLAEFRCSATGSPT-------PTLEWTGGPGGQLPAKAQIHGGI-----LRLPA 1922
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP--PQIMNISSDITVNEGSSVTLLCLAIGR 155
V+ D+ Y C + + +R L V P++ V+ G +V L C A G
Sbjct: 1923 VEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGV 1982
Query: 156 PEPTVTWRHLSVKEGQGFV-------SEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
P T+TWR KEG ++ L I I +G Y C A + R
Sbjct: 1983 PSATITWR----KEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQAR- 2037
Query: 209 VKITV------NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA--TGL 260
+++ V + PP ++ + V+ GQ L+C + A+ W++ L T +
Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV 2097
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNS 316
G R L VS D G Y C N G ASIT+ +V+ G +S
Sbjct: 2098 HGSR---------LRLPQVSPADSGEYVCRVENGSGPKEASITV----SVLHGTHS 2140
Score = 54.7 bits (130), Expect = 1e-07
Identities = 68/290 (23%), Positives = 107/290 (36%), Gaps = 51/290 (17%)
Query: 40 VRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V +G++ L C + + +V W R L A + R+ +L TP
Sbjct: 2448 VAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHG--SRLRLLQVTPA--------- 2496
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLIVQ----------VPPQIMNISSDITVNEGSSVTL 148
D G Y C V + + + V + +Q V + SS ++ G ++ L
Sbjct: 2497 ---DSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAP 204
CL + T+TW K G S + L I + SGEY C N +
Sbjct: 2554 NCLVASQAPHTITW----YKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSR 2609
Query: 205 DVRKVKITVN----------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEET 254
+ + +T+ PP ++ + V GQ L+C + P A W+K
Sbjct: 2610 ETSLI-VTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGG 2668
Query: 255 RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L + R + G S L +S D G Y C A N + ASI +
Sbjct: 2669 SLPS-----RHQTHG--SHLRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 22/223 (9%)
Query: 93 IMIQNVDVYDEGPYTCS----VQTDNHPKTSRVHLIVQVPPQIMNI-SSDITVNEGSSVT 147
+ I+NV + D G Y C+ D T V + +++I +TV G
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAE 1884
Query: 148 LLCLAIGRPEPTVTWR-----HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVA 202
C A G P PT+ W L K L + ++ +Y C A + A
Sbjct: 1885 FRCSATGSPTPTLEWTGGPGGQLPAKA----QIHGGILRLPAVEPTDQAQYLCRA-HSSA 1939
Query: 203 APDVRKVKITVN---YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 259
V + + V+ P + T V G+ L C A+ VP A W KE L
Sbjct: 1940 GQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQ 1999
Query: 260 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
R + ++TL ++ D G Y CVAT+ G A I
Sbjct: 2000 ARSERTD----IATLLIPAITTADAGFYLCVATSPAGTAQARI 2038
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/242 (22%), Positives = 87/242 (35%), Gaps = 28/242 (11%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV-----QVPPQIMNISSDITVNEGSSV 146
+++I + D G Y C + +R+ ++V PP + SS +V EG ++
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068
Query: 147 TLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
L C+ G VTW L + + SGEY C N + P
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENG-SGPKE 2127
Query: 207 RKVKITV--------NYPPYISKAK-------NTGVSVGQKGILSCEASAVPMAEFQWFK 251
+ ++V +Y P + ++ V+ GQ L+C A+ W K
Sbjct: 2128 ASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK 2187
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVI 311
L R + G S L V+ D G Y C G AS+ + +VI
Sbjct: 2188 RGGSLPA-----RHQTHG--SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVI 2240
Query: 312 DG 313
G
Sbjct: 2241 PG 2242
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/271 (23%), Positives = 99/271 (36%), Gaps = 47/271 (17%)
Query: 40 VRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIM-IQN 97
V +G++ L C + + +V W R L A + T S++ +
Sbjct: 2163 VAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQ---------------THGSLLRLHQ 2207
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP------PQIMNISSDITVNEGSSVTLLCL 151
V D G Y C V + P + V + ++ P + SS TV EG ++ L C+
Sbjct: 2208 VTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCV 2267
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPDVR 207
G+ VTW K G + + L I +G+Y C A N + A
Sbjct: 2268 VAGQAHAQVTW----YKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITV 2323
Query: 208 KVKIT----VNYP-----PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT 258
V T + YP P + ++ V+ GQ L+C A+ W K L
Sbjct: 2324 TVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP- 2382
Query: 259 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 289
+ ++ S L + S D G Y C
Sbjct: 2383 ------VRHQTHGSLLRLYQASPADSGEYVC 2407
Score = 49.7 bits (117), Expect = 4e-06
Identities = 70/297 (23%), Positives = 106/297 (35%), Gaps = 53/297 (17%)
Query: 40 VRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS-IMIQN 97
V +GE+ L C + + +V W R L + + T+ S + + +
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ---------------TRGSRLRLHH 2782
Query: 98 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQ--------VP-----PQIMNISSDITVNEGS 144
V D G Y C V + P + V + ++ VP P I S V EG
Sbjct: 2783 VSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQ 2842
Query: 145 SVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
++ L C+ G+ VTW L ++ + SGEY C
Sbjct: 2843 TLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 205 DVRKVKITVN-------------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFK 251
+ V +T+ P YI +A ++ V+ GQ L+C A+ W+K
Sbjct: 2903 EA-SVLVTIEPSSPGPIPAPGLAQPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQVTWYK 2960
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG-NTNASITLYGP 307
L R + G S L VS D G Y C A + G AS T+ P
Sbjct: 2961 RGGSLPA-----RHQTHG--SQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVP 3010
Score = 47.4 bits (111), Expect = 2e-05
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 32/231 (13%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQ---------VPPQIMNISSDITVNEGSSVTLLCLA 152
D G Y C V + P + V + ++ V P + SS V EG ++ L CL
Sbjct: 2401 DSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLV 2460
Query: 153 IGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
G+ VTW L + + SGEY C + + V +T
Sbjct: 2461 AGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEA-SVLVT 2519
Query: 213 VN------------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 260
+ YP I ++ + ++ G L+C ++ W+K L +
Sbjct: 2520 IQQRLSGSHSQGVAYPVRI-ESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPS-- 2576
Query: 261 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN--TNASITLYGPGA 309
R + G S L V+ D G Y C +N G+ T+ +T+ G G+
Sbjct: 2577 ---RHQIVG--SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622
Score = 46.2 bits (108), Expect = 4e-05
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-ITVNEGSSV 146
PTQ+ + N+ + + C ++D ++ + PPQ++ + I + G +V
Sbjct: 370 PTQFRCVSTNMCI--PASFHCDEESDCPDRSDEFGCM---PPQVVTPPRESIQASRGQTV 424
Query: 147 TLLCLAIGRPEPTVTWR----HLSVKEGQGFVSED--EYLEISDIKRDQSGEYECSALN 199
T C+AIG P P + WR H+ SE L I D+K G Y C A+N
Sbjct: 425 TFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 483
Score = 46.2 bits (108), Expect = 4e-05
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 34/232 (14%)
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIV-QVPPQIMNISSD----ITVNEGSSVTLLCL 151
+V D G Y C+ + + TSR L+V + P + + ++ + +V G+ VT +C
Sbjct: 1735 SVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICT 1794
Query: 152 AIGR-PEPTVTWRHL-SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN---------- 199
A + P T+ W L + K + + L I +++ +G Y C+ N
Sbjct: 1795 AKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTAT 1854
Query: 200 -DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT 258
V A + +PP ++ V GQ C A+ P +W T
Sbjct: 1855 LHVQASGTLSAPVVSIHPPQLT------VQPGQLAEFRCSATGSPTPTLEW--------T 1900
Query: 259 GLDGMRIENKGRM--STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 308
G G ++ K ++ L V D Y C A + G A L+ G
Sbjct: 1901 GGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1952
Score = 37.4 bits (85), Expect = 0.019
Identities = 47/201 (23%), Positives = 74/201 (36%), Gaps = 25/201 (12%)
Query: 116 PKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEGQG 172
P+T++ L+V+V P + V +G S +L C G P W V G
Sbjct: 1670 PETNQAPLVVEVHP------ARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQ 1723
Query: 173 FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY------ISKAKNTG 226
+ L ++ +G Y C+ N + + + ++ V P + + ++
Sbjct: 1724 QRHQGSELHFPSVQPSDAGVYICTCRN-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQS 1782
Query: 227 VSVGQKGILSCEA-SAVPMAEFQWFKEETRLATG-LDGMRIENKGRMSTLTFFNVSEKDY 284
V G C A S P W TRL G L ++ G LT NV D
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVW----TRLHNGKLPTRAMDFNG---ILTIRNVQLSDA 1835
Query: 285 GNYTCVATNKLGNTNASITLY 305
G Y C +N + TL+
Sbjct: 1836 GTYVCTGSNMFAMDQGTATLH 1856
Score = 32.0 bits (71), Expect = 0.81
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 1/69 (1%)
Query: 228 SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNY 287
S GQ +C A VP W + + + + ++G TL +V E D G Y
Sbjct: 419 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSH-PRVTVTSEGGRGTLIIRDVKESDQGAY 477
Query: 288 TCVATNKLG 296
TC A N G
Sbjct: 478 TCEAMNARG 486
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 92.8 bits (229), Expect = 4e-19
Identities = 74/281 (26%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 37 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 156 PEPTVTW----RHLSVKE----GQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 204
P P++TW R++S +E G V + L + I+ +GEY C+A N +
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI-GQ 393
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGM 263
D + + + V Y P + G + ++CE A P A WF++ L ++ +
Sbjct: 394 DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+I N S L SE D+GNY C A N++G + L
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 43 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 100
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 101 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 158
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 159 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 211
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 212 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 268
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/186 (19%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 44 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 102
E TL C D + + W R++ +++ ++D +++ + S+ ++++ D
Sbjct: 323 EQVTLTCEASGDPIPSITW--RTSTRNISSEEKTLDGHMVVRSHARVS-SLTLKSIQYTD 379
Query: 103 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW 162
G Y C+ + ++L VQ P++ + T EG+ V + C P T++W
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATISW 438
Query: 163 RHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
++GQ S + YLE++ + G Y C+A+N + + +
Sbjct: 439 ----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Query: 211 ITVNYP 216
+ + P
Sbjct: 495 VQADTP 500
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 227 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 282
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 283 DYGNYTCVATNKLGN 297
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 92.8 bits (229), Expect = 4e-19
Identities = 74/281 (26%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 37 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 156 PEPTVTW----RHLSVKE----GQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 204
P P++TW R++S +E G V + L + I+ +GEY C+A N +
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI-GQ 393
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGM 263
D + + + V Y P + G + ++CE A P A WF++ L ++ +
Sbjct: 394 DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+I N S L SE D+GNY C A N++G + L
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 43 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 100
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 101 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 158
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 159 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 211
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 212 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 268
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/186 (19%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 44 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 102
E TL C D + + W R++ +++ ++D +++ + S+ ++++ D
Sbjct: 323 EQVTLTCEASGDPIPSITW--RTSTRNISSEEKTLDGHMVVRSHARVS-SLTLKSIQYTD 379
Query: 103 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW 162
G Y C+ + ++L VQ P++ + T EG+ V + C P T++W
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATISW 438
Query: 163 RHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
++GQ S + YLE++ + G Y C+A+N + + +
Sbjct: 439 ----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Query: 211 ITVNYP 216
+ + P
Sbjct: 495 VQADTP 500
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 227 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 282
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 283 DYGNYTCVATNKLGN 297
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 88 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 650 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 709
Query: 144 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 199
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 710 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 769
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 770 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 828
Query: 258 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 829 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 874
Score = 90.5 bits (223), Expect = 2e-18
Identities = 79/293 (26%), Positives = 121/293 (41%), Gaps = 27/293 (9%)
Query: 23 PVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGNDKWSIDPRV 81
PV GD + ++ VTV + +L+C + + V ++WL +S PR+
Sbjct: 1651 PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL-------PFSPSPRL 1701
Query: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-ITV 140
+L + + + +V D Y C + L VQVPP+I + + +T
Sbjct: 1702 QVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 1758
Query: 141 NEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
SSV+L C P P VTW + LS+ E + L++ + SG Y C
Sbjct: 1759 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE 1818
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAVPMAEFQWFK 251
ALN A D + V+++V PP +A V VG K +LSCE A+P W+K
Sbjct: 1819 ALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK 1877
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ L + R L D G Y+C +N G + TL
Sbjct: 1878 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1927
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2870
Query: 153 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 2929
Query: 209 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 2930 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 2984
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+ STL VS +D G Y C A N++G T A
Sbjct: 2985 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 3017
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 2639 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2698
Query: 162 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 2699 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 2757
Query: 218 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 2758 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 2813
Query: 277 FNVSEKDYGNYTCVATNKLGN 297
+ S +D GNY C+A N G+
Sbjct: 2814 AHASPEDAGNYLCIAKNSAGS 2834
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 36 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 92
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 1849 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 1895
Query: 93 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 149
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 1954
Query: 150 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 1955 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 2012
Query: 206 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 2013 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 2071
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G + +L + D G YTCVA N G
Sbjct: 2072 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 103 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 159
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 1039 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1098
Query: 160 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 1099 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 1157
Query: 216 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 1158 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 1216
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 310
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 1217 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1255
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 158
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 376 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 435
Query: 159 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 214
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 436 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 494
Query: 215 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 495 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 551
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 314
+TL +V G + C ATN+ G A + + G GV
Sbjct: 552 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 594
Score = 76.3 bits (186), Expect = 4e-14
Identities = 79/312 (25%), Positives = 127/312 (40%), Gaps = 34/312 (10%)
Query: 37 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 888 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 938
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 155
DV+D G YTC +L V V P + S +TV EG +L C G
Sbjct: 939 RADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGV 998
Query: 156 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 205
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 999 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 1053
Query: 206 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 261
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 1054 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 1112
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 319
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 1113 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 1170
Query: 320 ALACLWLSGTLL 331
A L TLL
Sbjct: 1171 ITAALHSPLTLL 1182
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 148
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 2176 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2235
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 204
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 2236 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 2290
Query: 205 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 2291 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 2346
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+EN R + + + +D G YTC+A + G
Sbjct: 2347 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 2375
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 163
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2791
Query: 164 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 220
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 2792 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 2850
Query: 221 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 279
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 2851 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 2907
Query: 280 SEKDYGNYTCVATNKLGNTNASITL 304
+D G YTC A N +G + L
Sbjct: 2908 EGQDAGTYTCTAENAVGRARRRVHL 2932
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 140
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 1401 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 1460
Query: 141 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 192
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 1461 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1516
Query: 193 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 231
Y C A N VA D + + + PP K + +
Sbjct: 1517 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1575
Query: 232 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 1576 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 1632
Query: 292 TNKLG 296
+N++G
Sbjct: 1633 SNEVG 1637
Score = 72.4 bits (176), Expect = 5e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 159
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 1226 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1285
Query: 160 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 1286 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 1344
Query: 216 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 261
P I S + V+V L CEA A P W K+ +L G
Sbjct: 1345 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 1404
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G++I N ++D G YTCV TN+LG
Sbjct: 1405 GLQI-----------LNAQKEDAGQYTCVVTNELG 1428
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 75 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 134
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 2249 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2308
Query: 135 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 191
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 2309 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 2364
Query: 192 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 247
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 2365 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 2422
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 304
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 2423 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 2479
Query: 305 ------YGPGAVIDGVNSAS 318
GP AV VN +
Sbjct: 2480 TVPTIRSGPPAVNVSVNQTA 2499
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 148
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 1615 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1674
Query: 149 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 1675 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1734
Query: 205 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 1735 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1793
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ TL D G YTC A N G + L
Sbjct: 1794 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 1832
Score = 68.6 bits (166), Expect = 8e-12
Identities = 79/308 (25%), Positives = 124/308 (40%), Gaps = 30/308 (9%)
Query: 24 VRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVI 82
+RSG P A+ NV+V Q +A L C D V+W D+ +DPR
Sbjct: 2484 IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVPLDPRSP 2527
Query: 83 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE 142
P + S+ IQ V D G Y C L V PP I S++T+
Sbjct: 2528 RFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 2586
Query: 143 GSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
+ L C A G P+P V W +++G + L ++ S ++EC
Sbjct: 2587 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 2646
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQWFKEETR 255
N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W K +
Sbjct: 2647 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2705
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPGAVIDGV 314
L G R+ G + + G YTC A N G + + L V+ +
Sbjct: 2706 LGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQASPVVKPL 2762
Query: 315 NSASRALA 322
S RA+A
Sbjct: 2763 PSVVRAVA 2770
Score = 67.8 bits (164), Expect = 1e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 853 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 912
Query: 162 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 913 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGRSEKHYNLNVWVAP 971
Query: 218 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 274
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 972 VFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 1031
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++++ G YTC +N +GN++ + L
Sbjct: 1032 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 1059
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 150
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 274 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 333
Query: 151 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 334 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 392
Query: 207 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 393 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 452
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+E G S L + E G Y+CVA++ G
Sbjct: 453 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 483
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 40 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 2089
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 154
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 2090 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 2148
Query: 155 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 2149 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 2207
Query: 211 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 266
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 2208 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 2262
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +L V D G Y+CVA ++ G L
Sbjct: 2263 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 2297
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2505
Query: 153 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 2506 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 2564
Query: 209 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 263
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 2565 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2624
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 312
N L +D + CV +N++G + +T++ P + D
Sbjct: 2625 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2670
Score = 58.9 bits (141), Expect = 6e-09
Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 150 CLAIGRPEPTVTWRHLSVKE---GQGFVS--EDEYLEISDIKRDQSGEYECSALNDVAAP 204
C G P+P VTWR E GQ V+ E+ L ++ + SG+YEC A N+V +
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGST 83
Query: 205 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 252
R+ K+ V PP I + N GQ L C+A+ P+ E W K+
Sbjct: 84 S-RRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Score = 58.9 bits (141), Expect = 6e-09
Identities = 53/185 (28%), Positives = 76/185 (41%), Gaps = 26/185 (14%)
Query: 128 PPQIMNISS--DITVNEGSSVTLLCLAIGRPEPTVTWR-----------HLSVKEGQGFV 174
PP ++ + ++ G+ V L C G P P V W HL V+E
Sbjct: 215 PPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE----- 269
Query: 175 SEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKG 233
+ + L I+ G Y+C A + A R ++ V+ PP I + TG V+V +
Sbjct: 270 -DGQVLRITGSHVGDEGRYQCVAFSP-AGQQARDFQLRVHAPPTIWGSNETGEVAVMEDH 327
Query: 234 I--LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
+ L CEA VP WFK+ L T + GR L D G YTC A
Sbjct: 328 LVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRG-GRQ--LQLGRAQSSDAGVYTCKA 384
Query: 292 TNKLG 296
+N +G
Sbjct: 385 SNAVG 389
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 159
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 3000 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 3058
Query: 160 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 3059 IHW----IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 3114
Query: 213 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 266
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 3170
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+L NV D G Y CVA N LG+ A
Sbjct: 3171 ------SLWLENVETGDAGTYDCVAHNLLGSATA 3198
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ I + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 3081 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3140
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 204
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 3141 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 3196
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 245
R + V P S TGV G+K G+ + S + A
Sbjct: 3197 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 3237
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/241 (22%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN--EGSSVTLL 149
S+ + +V D G Y C + + R L+V VPP I V+ G S+TL
Sbjct: 58 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 117
Query: 150 CLAIGRPEPTVTWRH-------------------LSVKEGQGFVSEDEYLEISDIKRDQS 190
C A G P P + W G + E + L I+ +S
Sbjct: 118 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRS 177
Query: 191 GE--YECSALNDVAAPDVRKV----------KITVNYPPYISKAKNTGVSVGQKGI---L 235
G + AP + + PP + A +G G L
Sbjct: 178 GRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVEL 237
Query: 236 SCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 295
C S VP + +W K+ + G ++++ G++ +T +V D G Y CVA +
Sbjct: 238 QCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG--DEGRYQCVAFSPA 295
Query: 296 G 296
G
Sbjct: 296 G 296
Score = 35.8 bits (81), Expect = 0.056
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 12/95 (12%)
Query: 37 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++TVR G+ LRC T + WL L A + T S+ +
Sbjct: 3126 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-----------RLRTLPDGSLWL 3174
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ 130
+NV+ D G Y C T+R L+V+ PQ
Sbjct: 3175 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
Score = 35.0 bits (79), Expect = 0.096
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 14/98 (14%)
Query: 237 CEASAVPMAEFQWFK-EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 295
C P + W K + G G+ + +G +L +VS D G+Y C ATN++
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG---SLFLASVSPADSGDYECQATNEV 80
Query: 296 GNTN--ASITLYGPGAV--------IDGVNSASRALAC 323
G+T+ A + +Y P ++ + G+ S L C
Sbjct: 81 GSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLEC 118
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 88 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 143
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 559 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 618
Query: 144 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 199
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 619 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 678
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 257
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 679 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 737
Query: 258 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 738 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 783
Score = 90.5 bits (223), Expect = 2e-18
Identities = 79/293 (26%), Positives = 121/293 (41%), Gaps = 27/293 (9%)
Query: 23 PVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGNDKWSIDPRV 81
PV GD + ++ VTV + +L+C + + V ++WL +S PR+
Sbjct: 1560 PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL-------PFSPSPRL 1610
Query: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-ITV 140
+L + + + +V D Y C + L VQVPP+I + + +T
Sbjct: 1611 QVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 1667
Query: 141 NEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
SSV+L C P P VTW + LS+ E + L++ + SG Y C
Sbjct: 1668 ILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCE 1727
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAVPMAEFQWFK 251
ALN A D + V+++V PP +A V VG K +LSCE A+P W+K
Sbjct: 1728 ALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK 1786
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ L + R L D G Y+C +N G + TL
Sbjct: 1787 DGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1836
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2779
Query: 153 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 2838
Query: 209 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 267
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 2839 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 2893
Query: 268 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+ STL VS +D G Y C A N++G T A
Sbjct: 2894 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 2926
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 2548 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2607
Query: 162 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 2608 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 2666
Query: 218 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 276
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 2667 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 2722
Query: 277 FNVSEKDYGNYTCVATNKLGN 297
+ S +D GNY C+A N G+
Sbjct: 2723 AHASPEDAGNYLCIAKNSAGS 2743
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 36 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 92
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 1758 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 1804
Query: 93 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 149
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 1863
Query: 150 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 205
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 1864 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 1921
Query: 206 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 1922 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 1980
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G + +L + D G YTCVA N G
Sbjct: 1981 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 103 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 159
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 948 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1007
Query: 160 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 1008 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 1066
Query: 216 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 1067 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 1125
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 310
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 1126 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1164
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 158
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 285 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 344
Query: 159 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 214
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 345 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 403
Query: 215 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 271
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 404 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 460
Query: 272 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 314
+TL +V G + C ATN+ G A + + G GV
Sbjct: 461 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 503
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 148
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 2085 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2144
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 204
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 2145 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 2199
Query: 205 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 261
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 2200 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 2255
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+EN R + + + +D G YTC+A + G
Sbjct: 2256 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 2284
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 104 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 163
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2700
Query: 164 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 220
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 2701 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 2759
Query: 221 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 279
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 2760 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 2816
Query: 280 SEKDYGNYTCVATNKLGNTNASITL 304
+D G YTC A N +G + L
Sbjct: 2817 EGQDAGTYTCTAENAVGRARRRVHL 2841
Score = 75.5 bits (184), Expect = 6e-14
Identities = 79/312 (25%), Positives = 126/312 (40%), Gaps = 34/312 (10%)
Query: 37 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 797 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 847
Query: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 155
DV+D G YTC +L V V P + S +TV EG L C G
Sbjct: 848 RADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGV 907
Query: 156 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 205
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 908 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 962
Query: 206 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 261
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 963 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 1021
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 319
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 1022 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 1079
Query: 320 ALACLWLSGTLL 331
A L TLL
Sbjct: 1080 ITAALHSPLTLL 1091
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 140
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 1310 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKT 1369
Query: 141 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 192
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 1370 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1425
Query: 193 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 231
Y C A N VA D + + + PP K + +
Sbjct: 1426 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1484
Query: 232 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 291
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 1485 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 1541
Query: 292 TNKLG 296
+N++G
Sbjct: 1542 SNEVG 1546
Score = 73.2 bits (178), Expect = 3e-13
Identities = 74/285 (25%), Positives = 111/285 (38%), Gaps = 38/285 (13%)
Query: 37 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTIL--------YAGNDKWSIDPRVIILVNT 87
NV+ G+S TL C + V + WL + ++ Y + W +L
Sbjct: 27 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLL--- 83
Query: 88 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSS 145
S+ + D G Y+C + HL+V PP ++ + ++ G+
Sbjct: 84 DEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGAD 143
Query: 146 VTLLCLAIGRPEPTVTWR-----------HLSVKEGQGFVSEDEYLEISDIKRDQSGEYE 194
V L C G P P V W HL V+E + + L I+ G Y+
Sbjct: 144 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE------DGQVLRITGSHVGDEGRYQ 197
Query: 195 CSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGI--LSCEASAVPMAEFQWFK 251
C A + A R ++ V+ PP I + TG V+V + + L CEA VP WFK
Sbjct: 198 CVAFSP-AGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK 256
Query: 252 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ L T + GR L D G YTC A+N +G
Sbjct: 257 DGALLPTSTKVVYTRG-GRQ--LQLGRAQSSDAGVYTCKASNAVG 298
Score = 72.4 bits (176), Expect = 5e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 159
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 1135 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1194
Query: 160 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 215
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 1195 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 1253
Query: 216 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 261
P I S + V+V L CEA A P W K+ +L G
Sbjct: 1254 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 1313
Query: 262 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
G++I N ++D G YTCV TN+LG
Sbjct: 1314 GLQI-----------LNAQKEDAGQYTCVVTNELG 1337
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 75 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 134
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 2158 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2217
Query: 135 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 191
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 2218 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 2273
Query: 192 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 247
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 2274 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 2331
Query: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 304
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 2332 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 2388
Query: 305 ------YGPGAVIDGVNSAS 318
GP AV VN +
Sbjct: 2389 TVPTIRSGPPAVNVSVNQTA 2408
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 148
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 1524 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1583
Query: 149 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 204
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 1584 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1643
Query: 205 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 1644 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1702
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ TL D G YTC A N G + L
Sbjct: 1703 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 1741
Score = 68.6 bits (166), Expect = 8e-12
Identities = 79/308 (25%), Positives = 124/308 (40%), Gaps = 30/308 (9%)
Query: 24 VRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVI 82
+RSG P A+ NV+V Q +A L C D V+W D+ +DPR
Sbjct: 2393 IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVPLDPRSP 2436
Query: 83 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE 142
P + S+ IQ V D G Y C L V PP I S++T+
Sbjct: 2437 RFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 2495
Query: 143 GSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
+ L C A G P+P V W +++G + L ++ S ++EC
Sbjct: 2496 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECV 2555
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQWFKEETR 255
N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W K +
Sbjct: 2556 VSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2614
Query: 256 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPGAVIDGV 314
L G R+ G + + G YTC A N G + + L V+ +
Sbjct: 2615 LGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQASPVVKPL 2671
Query: 315 NSASRALA 322
S RA+A
Sbjct: 2672 PSVVRAVA 2679
Score = 67.4 bits (163), Expect = 2e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 161
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 762 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 821
Query: 162 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 822 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGHSEKHYNLNVWVAP 880
Query: 218 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 274
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 881 VFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 940
Query: 275 TFFNVSEKDYGNYTCVATNKLGNTNASITL 304
++++ G YTC +N +GN++ + L
Sbjct: 941 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 968
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 150
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 183 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 242
Query: 151 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 243 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 301
Query: 207 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 302 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 361
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
R+E G S L + E G Y+CVA++ G
Sbjct: 362 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 392
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 40 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 1998
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 154
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 1999 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 2057
Query: 155 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 2058 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 2116
Query: 211 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 266
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 2117 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 2171
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ +L V D G Y+CVA ++ G L
Sbjct: 2172 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 2206
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 152
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2414
Query: 153 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 208
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 2415 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 2473
Query: 209 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 263
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 2474 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2533
Query: 264 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 312
N L +D + CV +N++G + +T++ P + D
Sbjct: 2534 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2579
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 102 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 159
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 2909 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 2967
Query: 160 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 212
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 2968 IHW----IKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVL 3023
Query: 213 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 266
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 3079
Query: 267 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
+L NV D G Y CVA N LG+ A
Sbjct: 3080 ------SLWLENVETGDAGTYDCVAHNLLGSATA 3107
Score = 55.1 bits (131), Expect = 9e-08
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 92 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 151
S+ I+ + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 2990 SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3049
Query: 152 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 204
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 3050 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 3105
Query: 205 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 245
R + V P S TGV G+K G+ + S + A
Sbjct: 3106 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 3146
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/194 (25%), Positives = 72/194 (37%), Gaps = 27/194 (13%)
Query: 127 VPPQIMNISSDITVN--EGSSVTLLCLAIGRPEPTVTWRH-------------------L 165
VPP I V+ G S+TL C A G P P + W
Sbjct: 15 VPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGW 74
Query: 166 SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT 225
G + E + L I+ SG Y C A N R + V PP + A
Sbjct: 75 GQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAA 133
Query: 226 GVSVGQKGI---LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK 282
+G G L C S VP + +W K+ + G ++++ G++ +T +V
Sbjct: 134 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG-- 191
Query: 283 DYGNYTCVATNKLG 296
D G Y CVA + G
Sbjct: 192 DEGRYQCVAFSPAG 205
Score = 35.8 bits (81), Expect = 0.056
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 12/95 (12%)
Query: 37 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
++TVR G+ LRC T + WL L A + T S+ +
Sbjct: 3035 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-----------RLRTLPDGSLWL 3083
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ 130
+NV+ D G Y C T+R L+V+ PQ
Sbjct: 3084 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 92.0 bits (227), Expect = 7e-19
Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 32/285 (11%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTP 88
+ P+ N T +GE T C ++W R+ L N+K+ IL +
Sbjct: 212 SMPQKSFNATAERGEEMTFSCRASGSPEPAISWF-RNGKLIEENEKY-------ILKGSN 263
Query: 89 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 148
T+ + ++N+ D GPY C + L V V P I+ + ++ T G VTL
Sbjct: 264 TE--LTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQ-VTL 320
Query: 149 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLE---------------ISDIKRDQSGEY 193
+C A G P P +TW+ +G F D+ L+ I D+K SG Y
Sbjct: 321 VCDAEGEPIPEITWKR--AVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRY 378
Query: 194 ECSALNDVAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 252
+C A + + + + + + Y P +IS G +SC+ + P A W ++
Sbjct: 379 DCEAASRIGGHQ-KSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRD 437
Query: 253 ETRL-ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 296
+ L A ++ + GR L S+ D+G Y C ATN +G
Sbjct: 438 KLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 88.2 bits (217), Expect = 1e-17
Identities = 82/292 (28%), Positives = 127/292 (43%), Gaps = 29/292 (9%)
Query: 30 TFPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSI-DPRVIILVNT 87
TF + + +QGE A + C + V+WL Y + +I D R +L N
Sbjct: 116 TFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWL------YHNEEVTTISDNRFAMLANN 169
Query: 88 PTQYSIMIQNVDVYDEGPYTCS--VQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEG 143
++ I N++ DEG Y C V+ + +IV VPP I S + T G
Sbjct: 170 ----NLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERG 225
Query: 144 SSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEIS--DIKRDQSGEYECSALN 199
+T C A G PEP ++W ++E + ++ + E++ +I G Y C A N
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATN 285
Query: 200 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE-----T 254
A D ++ + V P+I + KN + L C+A P+ E W + T
Sbjct: 286 K-AGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFT 344
Query: 255 RLATGLDGMRIENKGR--MSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
LDG RIE KG+ S+L +V D G Y C A +++G S+ L
Sbjct: 345 EGDKSLDG-RIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYL 395
Score = 38.5 bits (88), Expect = 0.009
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 227 VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGN 286
+SVG+ +C A P + W+ + + ++ +G S LT +N + +D G
Sbjct: 32 LSVGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGI 90
Query: 287 YTCVATNKLGNT 298
Y C AT+ G T
Sbjct: 91 YRCQATDAKGQT 102
Score = 30.8 bits (68), Expect = 1.8
Identities = 36/171 (21%), Positives = 64/171 (37%), Gaps = 29/171 (16%)
Query: 136 SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDI 185
S + ++ G S C AIG PE ++ W + +G+ +S L I +
Sbjct: 28 SKVELSVGESKFFTCTAIGEPE-SIDWYN---PQGEKIISTQRVVVQKEGVRSRLTIYNA 83
Query: 186 KRDQSGEYECSALN----DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASA 241
+ +G Y C A + A V ++ + + +S + G+ + C S+
Sbjct: 84 NIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQE---FKQGEDAEVVCRVSS 140
Query: 242 VPMAEFQWFKEETRLATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTC 289
P W + T D N+ M + L N+++ D G Y C
Sbjct: 141 SPAPAVSWLYHNEEVTTISD-----NRFAMLANNNLQILNINKSDEGIYRC 186
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 91.7 bits (226), Expect = 9e-19
Identities = 72/291 (24%), Positives = 119/291 (40%), Gaps = 31/291 (10%)
Query: 37 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 155
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 156 PEPTVTW----RHLSVKEGQGFVSEDEY-----------------LEISDIKRDQSGEYE 194
P P++TW R++S +E + ++ L + I+ +GEY
Sbjct: 335 PIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 394
Query: 195 CSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEET 254
C+A N + D + + + V Y P + G + ++CE A P A WF++
Sbjct: 395 CTASNTI-GQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQ 453
Query: 255 RL-ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
L ++ ++I N S L SE D+GNY C A N++G + L
Sbjct: 454 LLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 504
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 43 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 100
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 101 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 158
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 159 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 211
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 212 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 268
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/195 (20%), Positives = 78/195 (40%), Gaps = 29/195 (14%)
Query: 44 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWS---------IDPRVIILVNTPTQYSI 93
E TL C D + + W ST + +K S +D +++ + S+
Sbjct: 323 EQVTLTCEASGDPIPSITW-RTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVS-SL 380
Query: 94 MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAI 153
++++ D G Y C+ + ++L VQ P++ + T EG+ V + C
Sbjct: 381 TLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVF 439
Query: 154 GRPEPTVTWRHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDV 201
P T++W ++GQ S + YLE++ + G Y C+A+N +
Sbjct: 440 AYPSATISW----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 495
Query: 202 AAPDVRKVKITVNYP 216
+ + + + P
Sbjct: 496 GQESLEFILVQADTP 510
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 227 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 282
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 283 DYGNYTCVATNKLGN 297
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|205277425 immunoglobulin superfamily, member 9 isoform a [Homo
sapiens]
Length = 1179
Score = 87.4 bits (215), Expect = 2e-17
Identities = 86/301 (28%), Positives = 126/301 (41%), Gaps = 30/301 (9%)
Query: 37 NVTVRQGESATLRCTIDDRVTR-----VAWLNRSTIL----YAGNDKWSIDPRVIILVNT 87
+V R GES L C + R + WL +L G IDP + V
Sbjct: 28 SVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRL 87
Query: 88 PTQYSIMIQNVDVYDEGPYTCSV-------QTDNHPKTSRVHLIVQVPPQIMNISSDIT- 139
S+ I+ + V D+G Y C V D+ S VHL V PPQ +
Sbjct: 88 QKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLE 147
Query: 140 VNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVS-EDEYLEISDIKRDQSGEYECS 196
V E VTL C+A G P P VTW R + +GQG V ++ L I ++R SG Y C
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQ 207
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM-AEFQWFKEETR 255
A + + + + P + KN+ V+ Q L+C A A P + WF++
Sbjct: 208 ASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267
Query: 256 LATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTCVATNKL---GNTNASITLYGPGA 309
+ R++ + R+ +L D G YTCV +N L + +A +T+ P
Sbjct: 268 V---FHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQ 324
Query: 310 V 310
V
Sbjct: 325 V 325
Score = 70.9 bits (172), Expect = 2e-12
Identities = 73/288 (25%), Positives = 111/288 (38%), Gaps = 28/288 (9%)
Query: 40 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V++ E TLRC + V W R L G + + ++ I+ V
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-----------NGTLRIRRV 196
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP-E 157
+ G YTC + T L+V PP I+ + TVN V+L C A P
Sbjct: 197 ERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPAN 256
Query: 158 PTVTW-------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
T +W H+S + + + D L + + D +G Y C N + P
Sbjct: 257 LTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAY 316
Query: 211 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEF-QWFKEETRLATGLDGMRIENK 268
+TV YP + + T + +G G++ C A P F W K+ L LD ++
Sbjct: 317 LTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQ--LDKFPGWSQ 374
Query: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS----ITLYGPGAVID 312
G +L +E G Y+C N LG S + L P A I+
Sbjct: 375 GTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIE 422
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 75 WSIDPRVIILVNTP-----TQYSIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIV 125
W+ D + + L P T+ S++I + G Y+C S+ T +RV ++
Sbjct: 357 WTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRV--LL 414
Query: 126 QVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEIS 183
+ PP + + E G + + C A G P P V+W + +GQ V + L +
Sbjct: 415 KAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILR 474
Query: 184 DIKRDQSGEYECSALNDVA 202
+ ++ G +ECSA N VA
Sbjct: 475 PLTKEAHGHWECSASNAVA 493
>gi|205277423 immunoglobulin superfamily, member 9 isoform b [Homo
sapiens]
Length = 1163
Score = 86.7 bits (213), Expect = 3e-17
Identities = 82/283 (28%), Positives = 118/283 (41%), Gaps = 27/283 (9%)
Query: 37 NVTVRQGESATLRCTIDDRVTR-----VAWLNRSTIL----YAGNDKWSIDPRVIILVNT 87
+V R GES L C + R + WL +L G IDP + V
Sbjct: 28 SVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRL 87
Query: 88 PTQYSIMIQNVDVYDEGPYTCSV-------QTDNHPKTSRVHLIVQVPPQIMNISSDIT- 139
S+ I+ + V D+G Y C V D+ S VHL V PPQ +
Sbjct: 88 QKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLE 147
Query: 140 VNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVS-EDEYLEISDIKRDQSGEYECS 196
V E VTL C+A G P P VTW R + +GQG V ++ L I ++R SG Y C
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQ 207
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM-AEFQWFKEETR 255
A + + + + P + KN+ V+ Q L+C A A P + WF++
Sbjct: 208 ASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267
Query: 256 LATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTCVATNKL 295
+ R++ + R+ +L D G YTCV +N L
Sbjct: 268 V---FHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGL 307
Score = 57.4 bits (137), Expect = 2e-08
Identities = 70/287 (24%), Positives = 104/287 (36%), Gaps = 42/287 (14%)
Query: 40 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 98
V++ E TLRC + V W R L G + + ++ I+ V
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-----------NGTLRIRRV 196
Query: 99 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP-E 157
+ G YTC + T L+V PP I+ + TVN V+L C A P
Sbjct: 197 ERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPAN 256
Query: 158 PTVTW-------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 210
T +W H+S + + + D L + + D +G Y C N + P
Sbjct: 257 LTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAY 316
Query: 211 ITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF-QWFKEETRLATGLDGMRIENKG 269
+TV P G++ C A P F W K+ L LD ++G
Sbjct: 317 LTVLCMP---------------GVIRCPVRANPPLLFVSWTKDGKALQ--LDKFPGWSQG 359
Query: 270 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS----ITLYGPGAVID 312
+L +E G Y+C N LG S + L P A I+
Sbjct: 360 TEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIE 406
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 75 WSIDPRVIILVNTP-----TQYSIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIV 125
W+ D + + L P T+ S++I + G Y+C S+ T +RV ++
Sbjct: 341 WTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRV--LL 398
Query: 126 QVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEIS 183
+ PP + + E G + + C A G P P V+W + +GQ V + L +
Sbjct: 399 KAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILR 458
Query: 184 DIKRDQSGEYECSALNDVA 202
+ ++ G +ECSA N VA
Sbjct: 459 PLTKEAHGHWECSASNAVA 477
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 85.9 bits (211), Expect = 5e-17
Identities = 73/288 (25%), Positives = 114/288 (39%), Gaps = 40/288 (13%)
Query: 38 VTVRQGESATLRCTIDDRVTRV--AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
V+VR+G+ L C+ + +W+ + D R I T Y +
Sbjct: 205 VSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDS-----RRFISQETGNLYISKV 259
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----------------I 138
Q DV G Y C V K + + V PP + + +D +
Sbjct: 260 QTSDV---GSYICLV------KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 310
Query: 139 TVNEGSSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
T +G++V + C A+G P PT+TW ++ + LEI +++ D +G YEC
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECR 370
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 256
A N R YP ++ K +T + G C+A+ P ++W K L
Sbjct: 371 AENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL 430
Query: 257 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ R+E L NV++ D G Y C+A NK G AS L
Sbjct: 431 S---PQSRVEMVN--GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHP--KTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLL 149
+MI NV+ D G Y C + ++ + ++ P +N + I V + V +
Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 502
Query: 150 CLAIGRPEPTVTWR--HLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
C G P+PT++W+ +V+E + + D L I + + G+Y C N + ++
Sbjct: 503 CKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEI 562
Query: 207 RKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEA 239
++V P I K T ++VG+ +L+C+A
Sbjct: 563 -IASLSVKEPTRIELTPKRTELTVGESIVLNCKA 595
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/171 (23%), Positives = 62/171 (36%), Gaps = 17/171 (9%)
Query: 139 TVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY---------LEISDIKRDQ 189
T ++ V L C G P P+ W ++ G E +Y + + +
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRW----LRNGTEIDLESDYRYSLIDGTFIISNPSEAKD 167
Query: 190 SGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV--GQKGILSCEASA-VPMAE 246
SG Y+C A N V + R+ + Y S + VSV GQ +L C P
Sbjct: 168 SGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEII 227
Query: 247 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
+ W E D R ++ L V D G+Y C+ N + N
Sbjct: 228 YSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKNTVTN 277
Score = 36.6 bits (83), Expect = 0.033
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 16/111 (14%)
Query: 196 SALNDVAAPDVRKVKITVNYPPYISKAKNTGV----SVGQKGILSCEASAVPMAEFQWFK 251
S +N + D K +V+Y P + + + S +K L+CE P+ ++W +
Sbjct: 78 SPINLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLR 137
Query: 252 EETRLATGLDGMRIENKGRMS----TLTFFNVSE-KDYGNYTCVATNKLGN 297
T + +E+ R S T N SE KD G+Y C+ATN +G+
Sbjct: 138 NGTEID-------LESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGS 181
Score = 28.5 bits (62), Expect = 8.9
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP 129
+MI+N+ + G Y C VQT + L+V+ PP
Sbjct: 635 LMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP 671
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 85.9 bits (211), Expect = 5e-17
Identities = 73/288 (25%), Positives = 114/288 (39%), Gaps = 40/288 (13%)
Query: 38 VTVRQGESATLRCTIDDRVTRV--AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 95
V+VR+G+ L C+ + +W+ + D R I T Y +
Sbjct: 131 VSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDS-----RRFISQETGNLYISKV 185
Query: 96 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----------------I 138
Q DV G Y C V K + + V PP + + +D +
Sbjct: 186 QTSDV---GSYICLV------KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 236
Query: 139 TVNEGSSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEISDIKRDQSGEYECS 196
T +G++V + C A+G P PT+TW ++ + LEI +++ D +G YEC
Sbjct: 237 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECR 296
Query: 197 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 256
A N R YP ++ K +T + G C+A+ P ++W K L
Sbjct: 297 AENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL 356
Query: 257 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
+ R+E L NV++ D G Y C+A NK G AS L
Sbjct: 357 S---PQSRVEMVN--GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHP--KTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLL 149
+MI NV+ D G Y C + ++ + ++ P +N + I V + V +
Sbjct: 369 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 428
Query: 150 CLAIGRPEPTVTWR--HLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
C G P+PT++W+ +V+E + + D L I + + G+Y C N + ++
Sbjct: 429 CKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEI 488
Query: 207 RKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEA 239
++V P I K T ++VG+ +L+C+A
Sbjct: 489 -IASLSVKEPTRIELTPKRTELTVGESIVLNCKA 521
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/171 (23%), Positives = 62/171 (36%), Gaps = 17/171 (9%)
Query: 139 TVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY---------LEISDIKRDQ 189
T ++ V L C G P P+ W ++ G E +Y + + +
Sbjct: 38 TDSDEKKVALNCEVRGNPVPSYRW----LRNGTEIDLESDYRYSLIDGTFIISNPSEAKD 93
Query: 190 SGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV--GQKGILSCEASA-VPMAE 246
SG Y+C A N V + R+ + Y S + VSV GQ +L C P
Sbjct: 94 SGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEII 153
Query: 247 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 297
+ W E D R ++ L V D G+Y C+ N + N
Sbjct: 154 YSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKNTVTN 203
Score = 28.5 bits (62), Expect = 8.9
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP 129
+MI+N+ + G Y C VQT + L+V+ PP
Sbjct: 561 LMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP 597
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 85.5 bits (210), Expect = 6e-17
Identities = 77/311 (24%), Positives = 120/311 (38%), Gaps = 60/311 (19%)
Query: 11 SATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILY 69
+A LF P + R T+ G+ TL C + V R+ W L
Sbjct: 230 AAEDTRLFAPSIKARFPAETYALV--------GQQVTLECFAFGNPVPRIKWRKVDGSL- 280
Query: 70 AGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP 129
+ +W T + ++ I +V DEG Y C + T + +IVQ P
Sbjct: 281 --SPQW-----------TTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQP 327
Query: 130 QIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY------LEIS 183
+ + + SD + GS++ C A G+P PTV W ++ G+ S++ L S
Sbjct: 328 EWLKVISDTEADIGSNLRWGCAAAGKPRPTVRW----LRNGEPLASQNRVEVLAGDLRFS 383
Query: 184 DIKRDQSGEYECSALN-------------DVAAPDVRKVKITVNYPPYISKAKNTGVSVG 230
+ + SG Y+C A N APD R + P + G
Sbjct: 384 KLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIP----------AARG 433
Query: 231 QKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCV 290
+ ++ C+ A P A W K T + + + G TL N+S D G YTC
Sbjct: 434 GEILIPCQPRAAPKAVVLWSK-GTEILVNSSRVTVTPDG---TLIIRNISRSDEGKYTCF 489
Query: 291 ATNKLGNTNAS 301
A N +G N++
Sbjct: 490 AENFMGKANST 500
Score = 70.1 bits (170), Expect = 3e-12
Identities = 47/162 (29%), Positives = 67/162 (41%), Gaps = 5/162 (3%)
Query: 143 GSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVA 202
G VTL C A G P P + WR + + + + L+I + + G YEC A N
Sbjct: 254 GQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKG 313
Query: 203 APDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 262
V+ I P ++ +T +G C A+ P +W + LA+
Sbjct: 314 RDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS---Q 370
Query: 263 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
R+E L F +S +D G Y CVA NK G AS L
Sbjct: 371 NRVEVLA--GDLRFSKLSLEDSGMYQCVAENKHGTIYASAEL 410
Score = 49.7 bits (117), Expect = 4e-06
Identities = 51/235 (21%), Positives = 88/235 (37%), Gaps = 13/235 (5%)
Query: 93 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV--PPQIMN-ISSDITVNEGSSVTLL 149
+ + + D G Y C + + + L VQ P +N + I G + +
Sbjct: 380 LRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIP 439
Query: 150 CLAIGRPEPTVTWR---HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 206
C P+ V W + V + V+ D L I +I R G+Y C A N + +
Sbjct: 440 CQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANS 499
Query: 207 RKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAE--FQWFKEETRLATGLDG-- 262
+ + + +++G L C AS P + F W ++ + G
Sbjct: 500 TGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 263 -MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGPGAVIDGV 314
R K + LT N + G YTC+A + + + A++ + GP GV
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGV 614
Score = 38.5 bits (88), Expect = 0.009
Identities = 39/165 (23%), Positives = 62/165 (37%), Gaps = 9/165 (5%)
Query: 146 VTLLCLAIGRPEPTVTWR----HLSVKEGQGFVSEDEYLEISD-IKRDQSGEYECSALND 200
V L C A P T W+ + ++ G L I + K +G Y+C A N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 201 VAAPDVRKVKITVNYPPYISKAKNTGVSV--GQKGILSCEASA-VPMAEFQWFKEETRLA 257
V R+ + + SK + V G +L C A P ++W E
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNF 176
Query: 258 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 302
DG ++ L + D GNY+C+AT+ + + S+
Sbjct: 177 IPTDGRHFVSQ-TTGNLYIARTNASDLGNYSCLATSHMDFSTKSV 220
Score = 37.0 bits (84), Expect = 0.025
Identities = 41/164 (25%), Positives = 64/164 (39%), Gaps = 28/164 (17%)
Query: 75 WSIDPRVII---LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI 131
WS +++ V +++I+N+ DEG YTC + S L V+ +I
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKI 511
Query: 132 MNISSDITVNEGSSVTLLCLAIGRP--EPTVTW----------------RHLSVKEGQGF 173
S +N G ++TL C A P + T TW R +VKE G
Sbjct: 512 TLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIG- 570
Query: 174 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 217
L I + + G+Y C A V + ++ + V PP
Sbjct: 571 -----DLTILNAQLRHGGKYTCMAQTVVDSAS-KEATVLVRGPP 608
Score = 30.0 bits (66), Expect = 3.1
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 228 SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSE-KDYGN 286
S ++ +L+C A A P A ++W T + G R + G L N ++ +D G
Sbjct: 52 STEEQVLLACRARASPPATYRWKMNGTEMKLE-PGSRHQLVG--GNLVIMNPTKAQDAGV 108
Query: 287 YTCVATNKLG 296
Y C+A+N +G
Sbjct: 109 YQCLASNPVG 118
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 85.5 bits (210), Expect = 6e-17
Identities = 92/304 (30%), Positives = 140/304 (46%), Gaps = 34/304 (11%)
Query: 24 VRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGNDKWSIDPRV 81
V+ FP NVTV +G +A L C +D T + W N + LY + K D R+
Sbjct: 21 VKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRI 79
Query: 82 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHL-IVQVP--PQIMNISSDI 138
++ + + SI + +V + DEG YTCS+ T KTS+ +L ++ VP PQI SS
Sbjct: 80 ELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKAYLTVLGVPEKPQISGFSS-- 136
Query: 139 TVNEGSSVTLLCLAIG-RPEPTVTW--RHLSVKEGQGFVSED---EYLEIS---DIKRDQ 189
V EG + L C G +P + W +K+ + ED + +S D + D+
Sbjct: 137 PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDR 196
Query: 190 SGE-------YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGV-SVGQKGILSCEASA 241
S + + +LN A P V + ++Y P + +T GQ IL+CE+
Sbjct: 197 SDDGVAVICRVDHESLN--ATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKG 254
Query: 242 VPMAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 300
P+ E W K+ L D R+ GR + F N + D G Y C ATN +G ++A
Sbjct: 255 KPLPEPVLWTKDGGELP---DPDRMVVSGRELNILFLN--KTDNGTYRCEATNTIGQSSA 309
Query: 301 SITL 304
L
Sbjct: 310 EYVL 313
Score = 32.7 bits (73), Expect = 0.47
Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 87 TPTQYSIMIQNVDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVPPQIMNISSDITVNE 142
T T S + VD D+G C V ++ T +V L + P + I S E
Sbjct: 183 TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE 242
Query: 143 GSSVTLLCLAIGRPEPT-VTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 195
G + L C + G+P P V W K+G D L I + + +G Y C
Sbjct: 243 GQPLILTCESKGKPLPEPVLW----TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRC 298
Query: 196 SALNDVAAPDVRKVKITVNYP 216
A N + V I + P
Sbjct: 299 EATNTIGQSSAEYVLIVHDVP 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,929,661
Number of Sequences: 37866
Number of extensions: 537052
Number of successful extensions: 5316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 201
Number of HSP's that attempted gapping in prelim test: 1457
Number of HSP's gapped (non-prelim): 2096
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.