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Search of human proteins with 55749431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749431 transcription elongation factor A (SII)-like 3
[Homo sapiens]
(200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 419 e-117
gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 419 e-117
gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 376 e-105
gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 354 2e-98
gi|55749459 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46
gi|55749442 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46
gi|65505873 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46
gi|55749451 transcription elongation factor A (SII)-like 4 [Homo... 182 2e-46
gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 171 3e-43
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 1e-09
gi|55749466 transcription elongation factor A (SII)-like 8 [Homo... 56 2e-08
gi|23503247 transcription elongation factor A (SII)-like 8 [Homo... 56 2e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 3e-08
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 54 7e-08
gi|55956788 nucleolin [Homo sapiens] 54 1e-07
gi|21361639 DIPB protein [Homo sapiens] 50 1e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 50 1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 2e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 3e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 49 3e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 49 3e-06
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 48 6e-06
gi|55743140 WW domain binding protein 5 [Homo sapiens] 47 8e-06
gi|55743147 WW domain binding protein 5 [Homo sapiens] 47 8e-06
gi|10047100 WW domain binding protein 5 [Homo sapiens] 47 8e-06
gi|55743145 WW domain binding protein 5 [Homo sapiens] 47 8e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 47 1e-05
gi|148746195 trichohyalin [Homo sapiens] 47 1e-05
gi|171916097 repetin [Homo sapiens] 47 1e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 47 1e-05
>gi|55749431 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 419 bits (1076), Expect = e-117
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD
Sbjct: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180
SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG
Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180
Query: 181 VRGVRGGGRGQRGLHDIPYL 200
VRGVRGGGRGQRGLHDIPYL
Sbjct: 181 VRGVRGGGRGQRGLHDIPYL 200
>gi|14249718 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 419 bits (1076), Expect = e-117
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD
Sbjct: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180
SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG
Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180
Query: 181 VRGVRGGGRGQRGLHDIPYL 200
VRGVRGGGRGQRGLHDIPYL
Sbjct: 181 VRGVRGGGRGQRGLHDIPYL 200
>gi|61175239 transcription elongation factor A (SII)-like 5 [Homo
sapiens]
Length = 206
Score = 376 bits (966), Expect = e-105
Identities = 182/206 (88%), Positives = 191/206 (92%), Gaps = 6/206 (2%)
Query: 1 MEKPYNKNEG------NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP 54
MEK Y +NEG NLE+EGKPEDE +DEGKSDEEEKPD+EGKTECEGKREDEGEP
Sbjct: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60
Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114
GDEGQLEDEG+QEKQG+SEGE KPQ EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT
Sbjct: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120
Query: 115 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 174
DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA
Sbjct: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180
Query: 175 PRGQRGVRGVRGGGRGQRGLHDIPYL 200
PRGQRGVRGVRGGGRGQ+ L D+PY+
Sbjct: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206
>gi|118600971 transcription elongation factor A (SII)-like 6 [Homo
sapiens]
Length = 183
Score = 354 bits (909), Expect = 2e-98
Identities = 171/183 (93%), Positives = 175/183 (95%), Gaps = 1/183 (0%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPD EGKTECEGKR+ EGEPGDEGQL
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDAEGKTECEGKRKAEGEPGDEGQL 60
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
ED+GSQEKQG+SEGEGKPQGEGKPASQAKPE QPRAAEKRPA DYVPRKAKRKTDRGTDD
Sbjct: 61 EDKGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRPAGDYVPRKAKRKTDRGTDD 120
Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRG 180
SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA +G G
Sbjct: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA-QGDNG 179
Query: 181 VRG 183
V G
Sbjct: 180 VSG 182
>gi|55749459 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
>gi|55749442 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
>gi|65505873 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
>gi|55749451 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
>gi|17933774 transcription elongation factor A (SII)-like 2 [Homo
sapiens]
Length = 227
Score = 171 bits (434), Expect = 3e-43
Identities = 95/229 (41%), Positives = 138/229 (60%), Gaps = 31/229 (13%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD----------------------------E 32
MEK +N+NEG N+GK ++E +P EGK + +
Sbjct: 1 MEKLFNENEGMPSNQGKIDNEEQPPHEGKPEVACILEDKKLENEGNTENTGKRVEEPLKD 60
Query: 33 EEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPES 92
+EKP+ GK + EGK E +G+ +G + EG E+ GR+EGEG+P E +P S+ +PES
Sbjct: 61 KEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPES 120
Query: 93 QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152
+ RAA KRPAED +PRKAKRKT++G K +E + + + S+E+M+RE +++R +++
Sbjct: 121 ETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVEDK 180
Query: 153 LRK-KQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
RK KQK+G F WMQR++QDPF PRG R RG G +R DIPY+
Sbjct: 181 RRKSKQKLGAFLWMQRNLQDPFYPRGPREFRG--GCRAPRRDTEDIPYV 227
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 60.1 bits (144), Expect = 1e-09
Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 18/184 (9%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKT-ECEGKREDEGEPGDEGQLEDEGSQEKQGR 71
E EG+ E E ++EG+ + EE+ + EG+ E EG+ E+ G+E + E+EG +E +G
Sbjct: 950 EEEGEWEGE---EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 72 SEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQE 131
EGEG+ + E + + + E + E E + + K G ++ +E+ +E
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 132 ---RHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGG 188
+ EE R+ G+ + +++ K G Q+ + V +G G
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQK-----------KSVTNTQGNG 1115
Query: 189 RGQR 192
+ QR
Sbjct: 1116 KEQR 1119
Score = 56.6 bits (135), Expect = 1e-08
Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 29/180 (16%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEG-KTECEGKREDEGEPGD---- 56
E+ + EG E EG+ E+E EG+ + EE+ + EG + E EGK E+EGE G+
Sbjct: 879 EEEEGEGEGEEEGEGEGEEE-----EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE 933
Query: 57 ----EGQLED---EGSQE------KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103
EG+ ED EG +E ++ EGEG+ +GEG+ + + E + E E
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE-GEEGEGEGEEEEGEGEGEE 992
Query: 104 DYVPRKAKRKTDRGTDDSPKDSQEDLQ---ERHLSSEEMMRECGDVSRAQEELRKKQKMG 160
+ + + + + G ++ + +E+ + E + EE E G+ +EE +++K G
Sbjct: 993 EEGEEEGEEEGE-GEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGEEEGEEREKEG 1050
Score = 56.2 bits (134), Expect = 2e-08
Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 13/161 (8%)
Query: 6 NKNEGNLENEGKPEDEVEPDDEGKS-DEEEKPDVEGKTECEGKREDEGEPGDEGQL---- 60
+K G +E G+ E E+ +E K D EE+ E + + +R E E G E +
Sbjct: 680 DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
E+EG +E++ EGEGK +GEG+ + + E + E++ E R K + D
Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGE---EVEGEREKEEGERKKEE----RAGKEEKGEEEGD 792
Query: 121 SPKDSQEDLQERHLSSEEMMR-ECGDVSRAQEELRKKQKMG 160
+ +E+ + R EE E G+V + E ++++ G
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833
Score = 56.2 bits (134), Expect = 2e-08
Identities = 43/140 (30%), Positives = 73/140 (52%), Gaps = 12/140 (8%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR---EDEGEPGD-EGQLED 62
+ E E EG+ E+ ++EG+ +EEE EGK E EG+ E+EGE G+ EG+ E+
Sbjct: 826 REEEEEEGEGEEEEGEGEEEEGEGEEEEG---EGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 63 -EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT--- 118
EG E++G EGE + +GEG+ + + E + E + E+ + + + + G
Sbjct: 883 GEGEGEEEGEGEGE-EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 119 DDSPKDSQEDLQERHLSSEE 138
+D + +E+ E EE
Sbjct: 942 EDGEGEGEEEEGEWEGEEEE 961
Score = 53.1 bits (126), Expect = 2e-07
Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 13/156 (8%)
Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65
++ E N E E E+E +E + D EE+ + EG EGK E EGE + + ++EG
Sbjct: 719 HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG----EGKEEGEGEEVEGEREKEEGE 774
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPA---------EDYVPRKAKRKTDR 116
++K+ R+ E K + EG + E++ R EK E R+ + +
Sbjct: 775 RKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834
Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152
G ++ + +E+ + E E G+ +EE
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Score = 50.8 bits (120), Expect = 7e-07
Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 5/147 (3%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE-CEGKREDEGEPGDEGQLEDEGSQE 67
EG E EG+ + ++EG+ + EE+ + EG+ E EG+ E+EGE G+ + E EG E
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE-GEGEEEEGEGKGE 922
Query: 68 KQG-RSEGEG-KPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125
++G EGEG + +GEG+ + E + E E+ + + + + ++ +
Sbjct: 923 EEGEEGEGEGEEEEGEGE-GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981
Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEE 152
+E+ E EE E + +EE
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Score = 50.1 bits (118), Expect = 1e-06
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+ + EG E E + E EVE + EG+ E E + EG+ E E +RE EGE G+E +
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE-EREKEGE-GEENRRN 1058
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99
E +E++G+ + G+ + E + + K S+ + + K
Sbjct: 1059 REEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Score = 49.3 bits (116), Expect = 2e-06
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 10/98 (10%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKT-----ECEGKREDEGEPGDEGQLE 61
+ EG E E + E E E + EG +EEE+ +VEG+ E EG+ E+ E G+E + E
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEG--EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99
EG + ++ R E E + EGK + E++ + E+
Sbjct: 1050 GEGEENRRNREEEE---EEEGKYQETGEEENERQDGEE 1084
Score = 46.2 bits (108), Expect = 2e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 23/174 (13%)
Query: 1 MEKPYNKNEGNLENE---GKPEDEVEPDDEGKSDEEEKP----------DVEG--KTECE 45
+E K EG + E GK E E D+G+ +EEE +VEG E +
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 46 GKREDEGEPG----DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKR- 100
G+RE+E E G +EG+ E+E + ++ EG+G+ +GE + E + E+
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 101 --PAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152
E+ + + + G + + + + +E EE E G+ +EE
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE-GEGEGEEEE 936
Score = 42.4 bits (98), Expect = 3e-04
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 7/142 (4%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEE--EKPDVEGKTECEGKREDEGEPGDEGQ 59
++ + K +G E E K ++ + + EE E+ EG+ E EG RE+E E EG+
Sbjct: 699 KEEWKKRDGE-EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE-EGDREEEEEKEGEGK 756
Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR---KTDR 116
E EG + + R + EG+ + E + + K E + E E + K + +
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816
Query: 117 GTDDSPKDSQEDLQERHLSSEE 138
G + K +E+ +E EE
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEE 838
Score = 41.6 bits (96), Expect = 5e-04
Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
EK + E + +G+ +++ E + + + ++ + G+ E E+EG+ +E + E
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752
Query: 62 DEGSQEKQGRS-EGE-GKPQGEGKPASQA-KPESQPRAAEKRPAEDYVPRKAKRKTDRGT 118
EG +E +G EGE K +GE K +A K E ++ E+ + + G
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812
Query: 119 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMG 160
+ + +E ER EE E + +EE +++ G
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854
Score = 41.6 bits (96), Expect = 5e-04
Identities = 38/155 (24%), Positives = 67/155 (43%), Gaps = 6/155 (3%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR---EDEGEPGDEG 58
E+ + EG E EG+ + +EG+ +EE+ E K E EG + E+E G G
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG-RG 805
Query: 59 QLEDEGSQEKQGR-SEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRG 117
+ ++EG + + G EG+G+ + E + + E + E E+ K + + + G
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 118 TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152
+ + E E E E G+ +EE
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEE-GEGEGEEEE 899
Score = 40.4 bits (93), Expect = 0.001
Identities = 51/226 (22%), Positives = 94/226 (41%), Gaps = 37/226 (16%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRED----------- 50
E+ NE N++ G +++ E + +D+ E EGK + G+ ED
Sbjct: 603 EQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS--EGKAKSVGEAEDGPEGRGDGTCE 660
Query: 51 EGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPR---AAEKRPAEDYVP 107
EG G E ++E + ++ + GE + GEG+ K E + R E++ E
Sbjct: 661 EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQ 720
Query: 108 RKAKRKTDRGTDDSPKDSQEDLQERHLSSE--------------EMMRECGDVSRAQEEL 153
++ ++ + G ++ + +E+ +R E E RE + R +EE
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 154 RKKQKMGGFHWMQRD-VQDPFAPRGQRGVRG--VRGG----GRGQR 192
K++ G Q + ++ RG+ G V GG G+G+R
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826
>gi|55749466 transcription elongation factor A (SII)-like 8 [Homo
sapiens]
Length = 117
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130
E EGKPQ K E P+ AE +P+E+ V ++A+ G + + +ED
Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66
Query: 131 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 167
RHL EEM+R ++ R +EE+R+ + K HW QR
Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104
>gi|23503247 transcription elongation factor A (SII)-like 8 [Homo
sapiens]
Length = 117
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130
E EGKPQ K E P+ AE +P+E+ V ++A+ G + + +ED
Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66
Query: 131 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 167
RHL EEM+R ++ R +EE+R+ + K HW QR
Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 55.5 bits (132), Expect = 3e-08
Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
+E P + E E+EG E E + + +S+ E D EG+ + E + + E +E Q
Sbjct: 2116 IEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP--RAAEKRPAEDYV-PRKAKRKTDRG 117
E EG + + +EGE +P+ EG A +A+ E+QP E AE+ P +T
Sbjct: 2176 ELEGVEAPE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEA 2233
Query: 118 TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 151
++ +S+ + Q S ++ G A E
Sbjct: 2234 EGEAQPESEGETQGEKKGSPQVSLGDGQSEEASE 2267
Score = 50.4 bits (119), Expect = 1e-06
Identities = 40/139 (28%), Positives = 71/139 (51%), Gaps = 16/139 (11%)
Query: 13 ENEGKPEDEV------EPDDEGKSDEEEKPDVEGKT-ECEGKREDEGE----PGDEGQLE 61
E + +PE EV E + + +S++ E +VE +T E EG+ + E E P EG+++
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010
Query: 62 DEGSQEKQGRSEG-EGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
E +E Q S+G E +P+ EG+ A + + E+Q + +P D V + + +
Sbjct: 2011 -EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAP---EAEEEAQE 2066
Query: 121 SPKDSQEDLQERHLSSEEM 139
+ + QE E H SE++
Sbjct: 2067 AEGEVQEAEGEAHPESEDV 2085
Score = 49.7 bits (117), Expect = 2e-06
Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 11/96 (11%)
Query: 9 EGNLENEGKPEDEVEPDDEG-----KSDEEEKPDVEG---KTECEGKREDEGEPGDEGQL 60
EG ++ + E+E +P+ +G KS+ EE +VEG KTE + + E +G E +
Sbjct: 2006 EGEMQ---EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRA 96
E + ++ + +EGE P+ E A +A+ E+QP +
Sbjct: 2063 EAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPES 2098
Score = 49.3 bits (116), Expect = 2e-06
Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 34/164 (20%)
Query: 1 MEKPYNKNEGNLENEG----KPEDEVEPDDEG----KSDEEEKPDVEGKTECEGKREDEG 52
+E P + E E+E + E EV+P+ EG ++++E +P+ E E + EDE
Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933
Query: 53 EP-GDEGQLEDEGSQEKQGRS------------EGEGKPQGEGKPASQAKPESQPRAAEK 99
E G E Q +E +QE +G++ E E +P+ E A + + E+Q E
Sbjct: 1934 ESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA 1993
Query: 100 RPAEDYV------------PRKAKRKTDRGTDDSPKDSQEDLQE 131
+P + V +A+ ++D G + PK E+ QE
Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESD-GVEAQPKSEGEEAQE 2036
Score = 48.5 bits (114), Expect = 4e-06
Identities = 48/195 (24%), Positives = 82/195 (42%), Gaps = 45/195 (23%)
Query: 1 MEKPYNKNEGNLENEG--KPE-----DEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE 53
+E P + E E+EG PE E E + + +S++ E P+ EG+ + E + + E
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894
Query: 54 PGDEGQLEDEGSQ----EKQGR----------SEGEGKPQGEGKPASQAKPESQPRAAEK 99
E Q E EG++ EK+ + +EGE +P+ EG A +A+ +Q +
Sbjct: 1895 AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQT 1954
Query: 100 RPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159
+P + + +SQE + EE E DV + E+ ++
Sbjct: 1955 QPESEVI-----------------ESQE-------AEEEAQPESEDVEALEVEVETQEAE 1990
Query: 160 GGFHWMQRDVQDPFA 174
G DV+ P A
Sbjct: 1991 GEAQPESEDVEAPEA 2005
Score = 48.5 bits (114), Expect = 4e-06
Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 14/143 (9%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
+E K EG+ + E + E ++E + E E + EG+ E + D E E Q
Sbjct: 2037 VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP 2096
Query: 61 EDEG---------SQEKQG----RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVP 107
E EG +Q+ +G +EGE +P+ EG A +A+ E+QP +E A+D
Sbjct: 2097 ESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPE-SEGVEAQDAEG 2155
Query: 108 RKAKRKTDRGTDDSPKDSQEDLQ 130
++ +++Q +L+
Sbjct: 2156 EAQPESEGIEAQEAEEEAQPELE 2178
Score = 41.2 bits (95), Expect = 6e-04
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 13/123 (10%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEG----KTECEGKREDEG--EPGDEGQLEDEGSQ 66
E EG+ + E E + +++ E +P++EG + E E + E EG P EG+ + E
Sbjct: 2184 EAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEG 2243
Query: 67 EKQGRSEGEGKPQ---GEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123
E QG E +G PQ G+G+ S+ ES E RP P G+ P
Sbjct: 2244 ETQG--EKKGSPQVSLGDGQ--SEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPS 2299
Query: 124 DSQ 126
S+
Sbjct: 2300 SSR 2302
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67
+E NL+ E + +P ++ E P+ EG E +P EG E +
Sbjct: 1810 HEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEG----------EAQPESEGVEAPEAEGD 1859
Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103
Q +EGE +P+ E A +A+ E+QP + + E
Sbjct: 1860 AQ-EAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894
Score = 38.5 bits (88), Expect = 0.004
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 14/141 (9%)
Query: 7 KNEGNLENEG-KPEDEVEPDDEGKSDEE------EKPDVEGKTECEGKREDEGEPGDEGQ 59
K E L+ EG + E+ E + EG+ +EE E+ EG E EG + +E + G EG
Sbjct: 1326 KTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQE-EGVQLEEVKEGPEGG 1384
Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119
L+ E +E G E EG P+ EG Q E+ + +D V + + +
Sbjct: 1385 LQGEALEE--GLKE-EGLPE-EGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAE 1440
Query: 120 DSPKDSQEDLQE--RHLSSEE 138
P + E+ E HLS +
Sbjct: 1441 PCPAEGTEEPTEPPSHLSETD 1461
Score = 37.4 bits (85), Expect = 0.009
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 3/94 (3%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G E EG E E + G + +++G+ G ++ G EG E E Q
Sbjct: 1788 GEAEQEG--EGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQ 1845
Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103
SEG P+ EG A +A+ E+QP + + E
Sbjct: 1846 PESEGVEAPEAEG-DAQEAEGEAQPESEDVEAPE 1878
Score = 36.2 bits (82), Expect = 0.019
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL 60
+E P + E E EG E E + + + + E P+ EG+ + E + E +GE Q+
Sbjct: 2196 IEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQV 2255
Query: 61 E-DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 111
+G E+ S P E +P P +RP P ++
Sbjct: 2256 SLGDGQSEEASES---SSPVPEDRPTPPPSPGGD--TPHQRPGSQTGPSSSR 2302
Score = 35.8 bits (81), Expect = 0.025
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 11/79 (13%)
Query: 13 ENEGKPEDEVEPDD----EGKSDEEEKPDVEGKTECEGKREDEG------EPGDEGQLED 62
E EG E+ V+ ++ EG +E + + +TE EG++E+E E G EG L++
Sbjct: 1311 EGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEG-LQE 1369
Query: 63 EGSQEKQGRSEGEGKPQGE 81
EG Q ++ + EG QGE
Sbjct: 1370 EGVQLEEVKEGPEGGLQGE 1388
Score = 35.0 bits (79), Expect = 0.043
Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 17/132 (12%)
Query: 13 ENEGKPEDEVEPDDEGKSDE---------EEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63
EN + E ++E EG E EE EG E + E+ E EGQ E+E
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353
Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAK--PES--QPRAAEKRPAEDYVPRKAK---RKTDR 116
E+ + GEG Q EG + K PE Q A E+ E+ +P + ++
Sbjct: 1354 AQLEEIEETGGEGL-QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSE 1412
Query: 117 GTDDSPKDSQED 128
+ K SQED
Sbjct: 1413 ASSPDGKGSQED 1424
Score = 32.3 bits (72), Expect = 0.28
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 46 GKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKP------ASQAKPESQPRAAEK 99
G R E +PGD+ LE G + G+ EG P + +P +S P+S +
Sbjct: 986 GLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQG 1045
Query: 100 RPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR 141
E A+ DR + S L R +S ++MR
Sbjct: 1046 AAPEGVSEAPAEAGADREAPAGCRVSLRALPGRVSASTQIMR 1087
Score = 29.3 bits (64), Expect = 2.3
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 12/85 (14%)
Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG--------QLE----DEGSQ 66
EDE E D E + + T E + +E + G EG QLE +EG Q
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ 1332
Query: 67 EKQGRSEGEGKPQGEGKPASQAKPE 91
E+ + E + +GEG+ +A+ E
Sbjct: 1333 EEGVQLEETKETEGEGQQEEEAQLE 1357
Score = 28.9 bits (63), Expect = 3.0
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 20 DEVEPDDEGKSDEEEKPDVE--GKTECEGKREDE-GEPGDEGQLEDEGSQEKQ--GRSEG 74
D + + EGK+ E G+ E EG+ E GE G +G ++ Q + G +
Sbjct: 1766 DAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825
Query: 75 EGKPQG-EGKPASQAKPESQPRA 96
G+ G EG A +A+ E+QP +
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPES 1848
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 54.3 bits (129), Expect = 7e-08
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 20/147 (13%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEG-------KREDEGEPGDEGQ 59
KNE + E + + E + GK D++EK + +GK + G K +++G+ G++G+
Sbjct: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK 183
Query: 60 LEDEGSQEK-------QGRSE-GEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 111
E +EK + R E G+GK +GK K + + ED R+
Sbjct: 184 GNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK-----EGKDVKVKEDEKEREDG 238
Query: 112 RKTDRGTDDSPKDSQEDLQERHLSSEE 138
++ + G ++ +EDL+E EE
Sbjct: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEE 265
Score = 43.9 bits (102), Expect = 9e-05
Identities = 37/158 (23%), Positives = 72/158 (45%), Gaps = 13/158 (8%)
Query: 9 EGNLEN---EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--REDEGEPGDEGQLEDE 63
E N+E+ +G + E + +E++K D E + E +G+ +ED+ E G+E +
Sbjct: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE-----D 156
Query: 64 GSQEKQGRSEGE-GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSP 122
G ++K G +GE K + +GK K + + ++ RK D
Sbjct: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
Query: 123 KDSQEDLQERHLSSEEMMRECG--DVSRAQEELRKKQK 158
K +++ ++ + +E RE G D +EE K+++
Sbjct: 217 KGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKE 254
Score = 43.1 bits (100), Expect = 2e-04
Identities = 23/105 (21%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 2 EKPYNKNEGNLENEGKP--EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQ 59
E K +G +GK ED E ++ K +E+ K +GK +GK + + + G + +
Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVK 227
Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
++++ + + G+ + G + GK K E + + ++ +D
Sbjct: 228 VKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
Score = 41.6 bits (96), Expect = 5e-04
Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRED----EGEPGD 56
+E+ YN+N N G+ + P E + E ++ ++E TE G++++ E + +
Sbjct: 72 VEEDYNENAKN----GEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEE 127
Query: 57 EGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116
E Q EDE Q ++ G+ +G+ + + + + ED K + +
Sbjct: 128 EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED----GKKGEDGK 183
Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 161
G + K+ ED +E EE +E GD ++ K K G
Sbjct: 184 GNGEDGKEKGEDEKE-----EEDRKETGDGKENEDGKEKGDKKEG 223
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/91 (37%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 7 KNEGNLENEGKPED---EVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63
K E E E + E + D + K D++E DV+ K E E +RED E DEG E+E
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK-EDEKEREDGKE--DEGGNEEE 248
Query: 64 GSQEKQG-RSEGEGKPQGEGKPASQAKPESQ 93
+EK+ + E EGK + E K K E Q
Sbjct: 249 AGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
Score = 35.4 bits (80), Expect = 0.033
Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 7/71 (9%)
Query: 2 EKPYNKNEGNLENEGKP----EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDE 57
E K +G+ + EGK EDE E +D GK DE + GK + + K E+EG+ DE
Sbjct: 210 ENEDGKEKGD-KKEGKDVKVKEDEKERED-GKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
Query: 58 GQLEDEGSQEK 68
+ ED+G +E+
Sbjct: 268 IK-EDDGKKEE 277
Score = 30.4 bits (67), Expect = 1.0
Identities = 23/54 (42%), Positives = 32/54 (59%), Gaps = 6/54 (11%)
Query: 15 EGKPEDEVEPDDEGKSDEE---EKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65
E + E E +DEG ++EE EK D+ K E EGK EDE + D+G+ E+ S
Sbjct: 230 EDEKEREDGKEDEGGNEEEAGKEKEDL--KEEEEGKEEDEIKE-DDGKKEEPQS 280
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 53.5 bits (127), Expect = 1e-07
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72
E++ EDE + +DE + ++E +P EDE + DE +D+ +E
Sbjct: 149 EDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEE 208
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQER 132
E +GK A++ P AE ED D DD D ++D +E
Sbjct: 209 EAMETTPAKGKKAAKVVPVKAKNVAED---EDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265
Query: 133 HLSSEEMMRECGDVSRAQEELRKKQ 157
EE ++E + ++E+ K++
Sbjct: 266 EEEEEEPVKEA--PGKRKKEMAKQK 288
Score = 37.0 bits (84), Expect = 0.011
Identities = 25/123 (20%), Positives = 53/123 (43%), Gaps = 21/123 (17%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKR----------------EDEGEPGD 56
E+E +DE + DD+ +++ + + T +GK+ ++E + D
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 57 EGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116
E +DE ++ + E + + E +P +A P +K A+ +AK++
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEA-----PGKRKKEMAKQKAAPEAKKQKVE 299
Query: 117 GTD 119
GT+
Sbjct: 300 GTE 302
Score = 34.7 bits (78), Expect = 0.056
Identities = 24/125 (19%), Positives = 52/125 (41%), Gaps = 18/125 (14%)
Query: 4 PYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKT------------------ECE 45
P +++E + ++E +D+ + +D+ + + E +GK E +
Sbjct: 182 PASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEED 241
Query: 46 GKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDY 105
+ ED+ + D+ +DE +E++ E E + GK + + A+K+ E
Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301
Query: 106 VPRKA 110
P A
Sbjct: 302 EPTTA 306
Score = 30.0 bits (66), Expect = 1.4
Identities = 16/50 (32%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE 51
E+ +++E + ++E +D+ E D+E + +EEE+P E GKR+ E
Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP----VKEAPGKRKKE 283
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 50.1 bits (118), Expect = 1e-06
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 6/162 (3%)
Query: 4 PYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63
P EG + E + + E E + E ++ EE + + E ++E E + E+E E + + E++
Sbjct: 69 PPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEED 128
Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK-TDRGTDDSP 122
+E + E E + + + S+A+ E++ + E R AKRK D G D S
Sbjct: 129 SEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLST 188
Query: 123 KDSQEDLQ----ERHLSSEEMMRECGDVSRAQEELRKKQKMG 160
QED Q + + + A EELR K G
Sbjct: 189 Y-CQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGG 229
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Query: 2 EKPYNKNEGNLENEGKPEDEV--EPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQ 59
E+ ++ E E E + E+E E D+E + D EE+ + E ++E E ++EGE EG+
Sbjct: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156
Query: 60 LEDEGSQEKQGRSEGE 75
E E + + E E
Sbjct: 157 TEAESEFDPEIEMEAE 172
Score = 33.1 bits (74), Expect = 0.16
Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 20 DEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLED--EGSQEKQGRSEGEGK 77
DE EPD+ ++E + G C E + L + GSQ ++GEG
Sbjct: 19 DECEPDEAPGAEEVCREC--GFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGA 76
Query: 78 PQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT-DRGTDDSPKDSQEDLQERHLSS 136
+ E + + + E + A E+ +E+ + + +T + D+S ++S+ED +E
Sbjct: 77 GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
Query: 137 EEMMRECGDVSRAQEE 152
+E E + + E
Sbjct: 137 QESEAEEDNQEEGESE 152
Score = 28.1 bits (61), Expect = 5.2
Identities = 13/48 (27%), Positives = 26/48 (54%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKRE 49
E+ ++ E E + + E E E + E +++ E P++E + E KR+
Sbjct: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRK 178
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 50.1 bits (118), Expect = 1e-06
Identities = 32/138 (23%), Positives = 68/138 (49%), Gaps = 10/138 (7%)
Query: 9 EGNLENEGKPED----EVEPDDEGKSDEEEK-PDVEGKTECEGKREDEGEPGDEGQLEDE 63
EG EG+ E+ E +P+ EG+++ + K + E + E EGK ++EGE DEG++ E
Sbjct: 760 EGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGE--DEGEIHAE 817
Query: 64 GSQEKQGRSEGEGK---PQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
+ K E E + + G+ + K ++ +E+ + +++ + ++
Sbjct: 818 DGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEE 877
Query: 121 SPKDSQEDLQERHLSSEE 138
++ +E+ +E +EE
Sbjct: 878 QEEEEEEEEEEEEKGNEE 895
Score = 43.9 bits (102), Expect = 9e-05
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 41/183 (22%)
Query: 15 EGKPEDEVE-----------PDDEGKSDEEEKPD-VEGKTECEGKRE---DEGEPGDEGQ 59
E KPE+E P + K D++E P E E E E +EGE EG+
Sbjct: 709 ESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGE 768
Query: 60 LEDEGSQEKQGRSEGEGKPQG-----------EGKPASQAKPESQPRA------------ 96
E++ E Q EGE + QG EGK ++ + E + A
Sbjct: 769 TEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGET 828
Query: 97 -AEKRPAEDYVPRKAKRK--TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEEL 153
+++ AE++ K K D G D +E+ +E EE E + +EE
Sbjct: 829 ESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888
Query: 154 RKK 156
+K
Sbjct: 889 EEK 891
Score = 43.5 bits (101), Expect = 1e-04
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 20/112 (17%)
Query: 6 NKNEGNLENEGKPEDEVEPDD---EGKSDEEEKPDVEGKTECEGKREDEG---------- 52
N+ EG +NEG+ E E+ +D +G E E ++ + E K +++G
Sbjct: 798 NEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGG 857
Query: 53 -------EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97
E ++ + E+E QE++ E E + +G +P S PE++ + A
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQA 909
Score = 42.0 bits (97), Expect = 3e-04
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 18/124 (14%)
Query: 7 KNEGNLENEGKPED-EVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLED--- 62
+ EG E +GK E+ E E + EGK D EG+ E E ED G+EG+ E
Sbjct: 780 EGEGETETQGKGEECEDENEAEGKGDN------EGEDEGEIHAEDGEMKGNEGETESQEL 833
Query: 63 ------EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 116
E +++G +G G G+ + + + E + E+ E+ + + + ++
Sbjct: 834 SAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE--EEEEEEEEEK 891
Query: 117 GTDD 120
G ++
Sbjct: 892 GNEE 895
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 49.3 bits (116), Expect = 2e-06
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE-PGDEGQLEDEGSQEKQGRSEGEGK 77
E E+E EGK + E + E + + KRE E E + G+ E +G ++K+ R + +
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 78 PQGEGKPASQ----AKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERH 133
+ E K + K E + R + ++ ++ +++ +R + K+ +E +ER
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER- 160
Query: 134 LSSEEMMRECGDVSRAQEELRKKQK 158
E RE V +EE ++K++
Sbjct: 161 --KERKKRERKQVGEKEEERKEKER 183
Score = 48.5 bits (114), Expect = 4e-06
Identities = 36/165 (21%), Positives = 78/165 (47%), Gaps = 15/165 (9%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSD-EEEKPDVEGKTECEG------------KREDEGE 53
+ EG E E + + E ++ K + E+E+ GK E +G +RE E +
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107
Query: 54 PGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 113
G+E + + ++++GR+ EGK + + + + + + R E+R E RK ++K
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER--ERKERKK 165
Query: 114 TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
+R ++ +++ + + E R+ R ++E R+++K
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/151 (24%), Positives = 74/151 (49%), Gaps = 4/151 (2%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
E E E + E + E + E K + E+ + + E E KRE G+ +G+ + E + K
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRE-RGKKEKKGERKKEERERK 98
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128
+ R E E K +GE K + K E + R + ++ ++ +++ +R + K+ +E
Sbjct: 99 KRRREKENK-EGEEKE-KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 129 LQERHLSSEEMMRECGDVSRAQEEL-RKKQK 158
+ER + ++ G+ ++E RK++K
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERK 187
Score = 45.4 bits (106), Expect = 3e-05
Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 5/134 (3%)
Query: 28 GKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG---RSEGEGKPQGEGKP 84
G E + + E +T EGK+E E E E + ++ +E++ R G+ + +GE K
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 85 ASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECG 144
+ + + + R E + E+ RK K K +RG S + + + +E E RE
Sbjct: 93 EERERKKRR-REKENKEGEEKEKRKKKEKKERGR-TSKEGKERERKEERKREERKERERK 150
Query: 145 DVSRAQEELRKKQK 158
R +E RK++K
Sbjct: 151 KEEREKERERKERK 164
Score = 43.1 bits (100), Expect = 2e-04
Identities = 34/173 (19%), Positives = 79/173 (45%), Gaps = 18/173 (10%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE------PG 55
EK + G E +G+ + E + E K EK + EG+ + + K++++ E G
Sbjct: 74 EKERKRERGKKEKKGERKKE---ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 115
E + ++E +E++ E + + + + + + K + + EK RK ++K +
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 116 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168
R + K+ + +ER +E ++ +E +++QK +W +++
Sbjct: 191 RNRKERKKERER--KERRERKKERKKK-------EERKKERQKDRQTNWREKE 234
Score = 40.8 bits (94), Expect = 8e-04
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--------REDEGEPGDEG 58
K E + + ++ E +++ K ++EK + G+T EGK + +E + +
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKE-RGRTSKEGKERERKEERKREERKERERK 150
Query: 59 QLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 118
+ E E +E++ R + E K GE + + K + + E+ E R+ K + +R
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 119 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK 155
+ K+ ++ +ER + RE R ++E +K
Sbjct: 211 ERKKKEERK--KERQKDRQTNWREKERGKRERKERKK 245
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/91 (30%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGS 65
+K +G L +E + E+E E ++E + DEEE+ + E + E E + E+E E +E + E+E +
Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Query: 66 -----QEKQGRSEGEGKPQGEGKPASQAKPE 91
QE + + P+ G + KPE
Sbjct: 309 PDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
Score = 40.0 bits (92), Expect = 0.001
Identities = 36/190 (18%), Positives = 81/190 (42%), Gaps = 11/190 (5%)
Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67
+E + + +G E E ++E + +EEE+ D E + E E + E+E E +E + E+E +E
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQE 127
++ + + A +A P + +P + + ++D D+ +
Sbjct: 305 EEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVI---VEVRSDDDKDEDTHSRKS 361
Query: 128 DLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGG 187
+ + + M R G++ ++ + K + R V +P P ++ G+
Sbjct: 362 TVTDESEMQDMMTR--GNLGLLEQAIALKAE------QVRTVCEPGCPPAEQSQLGLGEP 413
Query: 188 GRGQRGLHDI 197
G+ + L +
Sbjct: 414 GKAAKPLDTV 423
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 48.9 bits (115), Expect = 3e-06
Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Query: 7 KNEGNLENEGKPEDEVEP-----------DDEGKSDEEEKPDVEGKTECEGKREDEGEPG 55
K E E E +PE E E E K +E EK + EG+ E E EDEG
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKS 545
Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103
D+ + EG EK+G SE E Q EG+ ++A+ E EK+ E
Sbjct: 546 DQAE---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590
Score = 45.4 bits (106), Expect = 3e-05
Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 21/120 (17%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ--G 70
E EG+ E+E EG+ +EEE E EG + D+ E EG E EGS EK+
Sbjct: 522 EEEGEKEEE-----EGQEEEEE--------EDEGAKSDQAE---EGGSEKEGSSEKEEGE 565
Query: 71 RSEGEGKPQGEGKPASQAKPES--QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128
+ EGE + + EG+ A +AK E + ++ E E+ V K ++ PK E+
Sbjct: 566 QEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 624
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEK--PDVEGKTECEGKREDEGEPGDEGQLED-E 63
+ EG E E E+E E D+ KSD+ E+ + EG +E E ++EGE E + E+ E
Sbjct: 522 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 581
Query: 64 GSQEK--QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED--YVPRKAKRKTDRGTD 119
+EK + +SE + A KPE K P E+ P ++G
Sbjct: 582 AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 641
Query: 120 DSPKDSQED 128
PK E+
Sbjct: 642 PVPKSPVEE 650
Score = 32.0 bits (71), Expect = 0.36
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 19/118 (16%)
Query: 21 EVEPDDEGK----SDEEEKPDVEGKTECEG--------KRED---EGEPGDEGQLEDEGS 65
E E +EGK E+EK EG +E EG ++ED GE + ++E E
Sbjct: 758 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 817
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123
++ GR E +G P + + +K + V + ++ T G D + K
Sbjct: 818 EKGSGREEEKGVVTN----GLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATK 871
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/66 (31%), Positives = 29/66 (43%)
Query: 11 NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70
N E EGK E E E ++G EEEK V + E +G E ++ + EK
Sbjct: 803 NGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 862
Query: 71 RSEGEG 76
G+G
Sbjct: 863 SEGGDG 868
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 48.9 bits (115), Expect = 3e-06
Identities = 38/108 (35%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Query: 7 KNEGNLENEGKPEDEVEP-----------DDEGKSDEEEKPDVEGKTECEGKREDEGEPG 55
K E E E +PE E E E K +E EK + EG+ E E EDEG
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKS 169
Query: 56 DEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAE 103
D+ + EG EK+G SE E Q EG+ ++A+ E EK+ E
Sbjct: 170 DQAE---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214
Score = 45.4 bits (106), Expect = 3e-05
Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 21/120 (17%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ--G 70
E EG+ E+E EG+ +EEE E EG + D+ E EG E EGS EK+
Sbjct: 146 EEEGEKEEE-----EGQEEEEE--------EDEGAKSDQAE---EGGSEKEGSSEKEEGE 189
Query: 71 RSEGEGKPQGEGKPASQAKPES--QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128
+ EGE + + EG+ A +AK E + ++ E E+ V K ++ PK E+
Sbjct: 190 QEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEK--PDVEGKTECEGKREDEGEPGDEGQLED-E 63
+ EG E E E+E E D+ KSD+ E+ + EG +E E ++EGE E + E+ E
Sbjct: 146 EEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 205
Query: 64 GSQEK--QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED--YVPRKAKRKTDRGTD 119
+EK + +SE + A KPE K P E+ P ++G
Sbjct: 206 AKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 265
Query: 120 DSPKDSQED 128
PK E+
Sbjct: 266 PVPKSPVEE 274
Score = 32.0 bits (71), Expect = 0.36
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 19/118 (16%)
Query: 21 EVEPDDEGK----SDEEEKPDVEGKTECEG--------KRED---EGEPGDEGQLEDEGS 65
E E +EGK E+EK EG +E EG ++ED GE + ++E E
Sbjct: 382 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 441
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123
++ GR E +G P + + +K + V + ++ T G D + K
Sbjct: 442 EKGSGREEEKGVVTN----GLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATK 495
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/66 (31%), Positives = 29/66 (43%)
Query: 11 NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70
N E EGK E E E ++G EEEK V + E +G E ++ + EK
Sbjct: 427 NGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 486
Query: 71 RSEGEG 76
G+G
Sbjct: 487 SEGGDG 492
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 47.8 bits (112), Expect = 6e-06
Identities = 46/205 (22%), Positives = 80/205 (39%), Gaps = 26/205 (12%)
Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEE-----EKPDVEGKTECEGKREDEGEPG-DEGQ 59
+++EG+ + G E E ++ SD+E +K D + + ++E G DE +
Sbjct: 116 DEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDK 175
Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPA-------------EDYV 106
L++ EK ++ E +PQ Q E + + ++RP E+
Sbjct: 176 LQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQP 235
Query: 107 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRA----QEELRKKQKMGGF 162
+ K D+ P+ S E + RH EE + +R E LR K+K
Sbjct: 236 QLSDEEKMQNSDDERPQASDE--EHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIA 293
Query: 163 HWMQRDVQDPFAPRGQRGVRGVRGG 187
+ D D P+ G + GG
Sbjct: 294 SDSEAD-SDTEVPKDNSGTMDLFGG 317
Score = 42.0 bits (97), Expect = 3e-04
Identities = 37/171 (21%), Positives = 72/171 (42%), Gaps = 31/171 (18%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGK---SDEEEKPDVEGKTECEGKREDEGEPGDEG 58
E+ +E L+N DD+ K +D+EE+P + + E++ DE
Sbjct: 166 ERAQGSDEDKLQNS---------DDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDER 216
Query: 59 QLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA--EKRPAEDYVPRKAKRKTDR 116
+ + EKQ S+ E +PQ + Q + +P+A+ E R ++D + K ++ R
Sbjct: 217 PVASDNDDEKQ-NSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESAR 275
Query: 117 GTD----------------DSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 151
G+D DS DS ++ + + + ++ D+S +
Sbjct: 276 GSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSD 326
Score = 38.1 bits (87), Expect = 0.005
Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG-RS 72
++ E E + D G + ++ + + G D+ E GD GQ ++E G S
Sbjct: 10 SDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQ---PSNKELFGDDS 66
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK--TDRGTDDSPKDSQEDLQ 130
E EG G + +++ A+E+ ED P + ++ DD + + D
Sbjct: 67 EDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGG 126
Query: 131 ERHLSSE 137
H +E
Sbjct: 127 SHHSEAE 133
Score = 36.6 bits (83), Expect = 0.015
Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 14/139 (10%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+ N++E + ++ + D + D S+ + EG G E E ++ +
Sbjct: 82 ERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSD 141
Query: 62 DE--GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119
DE G ++K +S+ E + + +Q E D + + + TD
Sbjct: 142 DEKWGREDKSDQSDDEKIQNSDDEERAQGSDE------------DKLQNSDDDEKMQNTD 189
Query: 120 DSPKDSQEDLQERHLSSEE 138
D + D + + LS EE
Sbjct: 190 DEERPQLSDDERQQLSEEE 208
Score = 33.1 bits (74), Expect = 0.16
Identities = 37/176 (21%), Positives = 57/176 (32%), Gaps = 33/176 (18%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE---------- 51
E+P +E ++N + ++ SD+EE+ D + ++ EDE
Sbjct: 233 EQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAI 292
Query: 52 ----------GEPGDEGQLED--EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEK 99
P D D G+ + S+GE KP G+P + + E
Sbjct: 293 ASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEP 352
Query: 100 RPAEDYVPRKAKRKTDRGTD-----------DSPKDSQEDLQERHLSSEEMMRECG 144
P K TD G D P+ E EEM+ E G
Sbjct: 353 IPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEG 408
Score = 30.0 bits (66), Expect = 1.4
Identities = 31/152 (20%), Positives = 58/152 (38%), Gaps = 11/152 (7%)
Query: 30 SDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE-GKPASQA 88
+D E+ + +E E K D G D Q E+ S SE + +G+ G+P+++
Sbjct: 2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQ-ENAASGSNASGSESDQDERGDSGQPSNKE 60
Query: 89 --KPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSE-------EM 139
+S+ A D ++ +++ +D+ ++H SE E
Sbjct: 61 LFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEG 120
Query: 140 MRECGDVSRAQEELRKKQKMGGFHWMQRDVQD 171
R G ++ E +K W + D D
Sbjct: 121 HRSDGGSHHSEAEGSEKAHSDDEKWGREDKSD 152
>gi|55743140 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 47.4 bits (111), Expect = 8e-06
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125
Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++
Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56
Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164
+ED+ RHLS+E+M RE V E R + K+ W
Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92
Score = 38.1 bits (87), Expect = 0.005
Identities = 19/41 (46%), Positives = 24/41 (58%)
Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43
K K EG ENE +P+ E EP E K +EEEK + E K +
Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42
Score = 36.6 bits (83), Expect = 0.015
Identities = 18/33 (54%), Positives = 21/33 (63%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47
EGKPE+E EP E + EEKP+ E K E E K
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40
>gi|55743147 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 47.4 bits (111), Expect = 8e-06
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125
Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++
Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56
Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164
+ED+ RHLS+E+M RE V E R + K+ W
Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92
Score = 38.1 bits (87), Expect = 0.005
Identities = 19/41 (46%), Positives = 24/41 (58%)
Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43
K K EG ENE +P+ E EP E K +EEEK + E K +
Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42
Score = 36.6 bits (83), Expect = 0.015
Identities = 18/33 (54%), Positives = 21/33 (63%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47
EGKPE+E EP E + EEKP+ E K E E K
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40
>gi|10047100 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 47.4 bits (111), Expect = 8e-06
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125
Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++
Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56
Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164
+ED+ RHLS+E+M RE V E R + K+ W
Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92
Score = 38.1 bits (87), Expect = 0.005
Identities = 19/41 (46%), Positives = 24/41 (58%)
Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43
K K EG ENE +P+ E EP E K +EEEK + E K +
Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42
Score = 36.6 bits (83), Expect = 0.015
Identities = 18/33 (54%), Positives = 21/33 (63%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47
EGKPE+E EP E + EEKP+ E K E E K
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40
>gi|55743145 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 47.4 bits (111), Expect = 8e-06
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 66 QEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS 125
Q+ +G+ E E +P+ E +P + KPE + + E+ KAK S ++
Sbjct: 5 QKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--------KAKGTFRERLIQSLQEF 56
Query: 126 QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 164
+ED+ RHLS+E+M RE V E R + K+ W
Sbjct: 57 KEDIHNRHLSNEDMFRE---VDEIDEIRRVRNKLIVMRW 92
Score = 38.1 bits (87), Expect = 0.005
Identities = 19/41 (46%), Positives = 24/41 (58%)
Query: 3 KPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTE 43
K K EG ENE +P+ E EP E K +EEEK + E K +
Sbjct: 2 KSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEAKAK 42
Score = 36.6 bits (83), Expect = 0.015
Identities = 18/33 (54%), Positives = 21/33 (63%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK 47
EGKPE+E EP E + EEKP+ E K E E K
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPEEEEKLEEEAK 40
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 47.0 bits (110), Expect = 1e-05
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 16/192 (8%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74
+G P P GK E+ KP + GK G+ D GE G +G+ D G+ ++GR
Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGK---NGEPGDPGEDGRKGEKGDSGASGREGRDGP 1873
Query: 75 EGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHL 134
+G+ G Q P VP K DRG S K Q ER L
Sbjct: 1874 KGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGS-KGEQGLPGERGL 1932
Query: 135 SSE--------EMMRECGDVSRAQEELRK--KQKMGGFHWMQRDVQDPFAPRGQRGVRGV 184
E ++ G + A E+ + + G F + + P G++G G
Sbjct: 1933 RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992
Query: 185 RG--GGRGQRGL 194
G G G+RGL
Sbjct: 1993 EGPIGFPGERGL 2004
Score = 39.7 bits (91), Expect = 0.002
Identities = 52/196 (26%), Positives = 72/196 (36%), Gaps = 23/196 (11%)
Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75
G P + +P D G + G + G++ D G PG G + G + G E
Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642
Query: 76 GKPQGEGKPAS------QAKPESQPRAAEK----RPAED---YVPRKAKRKTDRGTDDSP 122
G P G P + P + EK P ED P + K DRG P
Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702
Query: 123 KDSQEDLQERHLSSEEMMRECGDV-SRAQEELRKKQKMGGFHWM--QRDVQDPFAPRGQR 179
R + + RE G+ R QE R + G +R ++ P G +
Sbjct: 1703 GP-----PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757
Query: 180 GVRGVRG--GGRGQRG 193
G GVRG G +G RG
Sbjct: 1758 GDPGVRGPAGEKGDRG 1773
Score = 39.7 bits (91), Expect = 0.002
Identities = 51/197 (25%), Positives = 73/197 (37%), Gaps = 26/197 (13%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G +EG P D P G+ P V G G++ D+G+PG++G+ GS +
Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV---GEKGDQGDPGEDGRNGSPGSSGPK 1693
Query: 70 GRSEGEGKPQGEGK-----PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD--SP 122
G G P G+ P ++ K E R E P +RG + P
Sbjct: 1694 GDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP 1753
Query: 123 KDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVR 182
Q D R + E+ GD R L + + G + P P G G
Sbjct: 1754 PGPQGDPGVRGPAGEK-----GD--RGPPGLDGRSGLDG----KPGAAGPSGPNGAAGKA 1802
Query: 183 GVRG-----GGRGQRGL 194
G G G RG++GL
Sbjct: 1803 GDPGRDGLPGLRGEQGL 1819
Score = 38.9 bits (89), Expect = 0.003
Identities = 46/185 (24%), Positives = 68/185 (36%), Gaps = 17/185 (9%)
Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75
G+ D P +G+S + KP G + G G+PG +G G + +QG
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL---PGLRGEQGLPGPS 1823
Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLS 135
G P GKP KP + E P + P + RK ++G + D +
Sbjct: 1824 GPPGLPGKPGEDGKPGLNGKNGE--PGD---PGEDGRKGEKGDSGASGREGRDGPKGERG 1878
Query: 136 SEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--GGRGQRG 193
+ ++ G Q G V P+G RG G +G G G+RG
Sbjct: 1879 APGILGPQGPPGLPGPVGPPGQGFPG-------VPGGTGPKGDRGETGSKGEQGLPGERG 1931
Query: 194 LHDIP 198
L P
Sbjct: 1932 LRGEP 1936
Score = 38.1 bits (87), Expect = 0.005
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 2/102 (1%)
Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83
P G + E KP + G G + G PG+ G+ ++G + +QGR G P G
Sbjct: 2027 PGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGP 2086
Query: 84 PASQAKPESQPRAAEKRPAEDYVP--RKAKRKTDRGTDDSPK 123
P S E P + AK + D PK
Sbjct: 2087 PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPK 2128
Score = 35.4 bits (80), Expect = 0.033
Identities = 47/180 (26%), Positives = 66/180 (36%), Gaps = 21/180 (11%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG------QLEDEGSQEK 68
+G+P D + G + P G+ EG R G GD G + D G
Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKR--PAEDYVPRKAKRKTDRGTDDSPKDSQ 126
GRS +GKP G P AA K P D +P + G P
Sbjct: 1778 DGRSGLDGKPGAAG-------PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830
Query: 127 EDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG 186
+ ++ E GD E+ RK +K G R+ +D P+G+RG G+ G
Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPG---EDGRKGEK-GDSGASGREGRD--GPKGERGAPGILG 1884
Score = 33.9 bits (76), Expect = 0.095
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Query: 18 PEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGK 77
P+ V+ G S E+ P ++G G D+G GD G +G + + G +G
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151
Query: 78 PQGEGKPASQAKPESQP 94
P G+ A PE +P
Sbjct: 2152 PGLPGE-RGMAGPEGKP 2167
Score = 33.9 bits (76), Expect = 0.095
Identities = 44/179 (24%), Positives = 66/179 (36%), Gaps = 20/179 (11%)
Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83
P G + + G +G R D G+PGD+G + G + G G +G+
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 84 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR-E 142
P + P P + P +D VP K D G + R L E ++
Sbjct: 2589 PGAAGIP-GDPGS----PGKDGVPGIRGEKGDVGF----------MGPRGLKGERGVKGA 2633
Query: 143 CG-DVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--GGRGQRGLHDIP 198
CG D + + G + ++ +P P GQ G G G G +G RG P
Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVP-GQSGAPGKEGLIGPKGDRGFDGQP 2691
Score = 33.9 bits (76), Expect = 0.095
Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 7/98 (7%)
Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGE---G 82
D+G+ E P + G G G PG G + G + QG+ +GE P GE G
Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQ-KGERGPPGERVVG 2754
Query: 83 KPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
P P + PA PR K + DD
Sbjct: 2755 APGVPGAPGERGEQGRPGPAG---PRGEKGEAALTEDD 2789
Score = 33.1 bits (74), Expect = 0.16
Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 6/111 (5%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74
+G+P P G P ++G G R D GE G G + G+ + EG
Sbjct: 1304 DGRPGS---PGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEG 1360
Query: 75 EGKPQGEGKPASQAKPESQPRAAEKRP-AEDYVPRKAKR--KTDRGTDDSP 122
G P +G P P + + P +P A + K DRG P
Sbjct: 1361 PGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPP 1411
Score = 32.7 bits (73), Expect = 0.21
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 6/95 (6%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G + G+ + E DEG + P G+ G G G++G D G +
Sbjct: 1625 GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRN 1684
Query: 70 GRSEGEGKPQGE-GKPASQAKP----ESQPRAAEK 99
G S G P+G+ G+P P ++ P A EK
Sbjct: 1685 G-SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREK 1718
Score = 32.0 bits (71), Expect = 0.36
Identities = 28/109 (25%), Positives = 39/109 (35%), Gaps = 5/109 (4%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
+G ++G+ P G E +P V G++ GK G GD G G +
Sbjct: 2637 DGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGD 2696
Query: 69 QGRSEGEGKPQGEGKPA-----SQAKPESQPRAAEKRPAEDYVPRKAKR 112
QG G P G P A P P + R E +K +R
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER 2745
Score = 31.6 bits (70), Expect = 0.47
Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 17/191 (8%)
Query: 18 PEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGK 77
P E +G S E+ P EG G+R +G+ G D G Q G + GE
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRG------DPGPQGPPGLALGERG 2025
Query: 78 PQG----EGKPASQAKPESQPRAA----EKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL 129
P G G+P P RA RP E + + ++G D P
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085
Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG--G 187
+ + E G ++ + G D Q P RG G++G RG G
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGD-QGPKGDRGVPGIKGDRGEPG 2144
Query: 188 GRGQRGLHDIP 198
RGQ G +P
Sbjct: 2145 PRGQDGNPGLP 2155
Score = 31.6 bits (70), Expect = 0.47
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 9/57 (15%)
Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEG 82
D+G + P ++G D GEPG GQ + G ++G + EGKP +G
Sbjct: 2124 DQGPKGDRGVPGIKG---------DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG 2171
Score = 31.6 bits (70), Expect = 0.47
Identities = 19/61 (31%), Positives = 26/61 (42%)
Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGK 83
P + G + E KP ++G G G+PG G G QG S +G+P G
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP 2214
Query: 84 P 84
P
Sbjct: 2215 P 2215
Score = 31.2 bits (69), Expect = 0.61
Identities = 41/177 (23%), Positives = 60/177 (33%), Gaps = 19/177 (10%)
Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE-----PGDEGQLEDEGSQEKQG 70
G E + P + G P +G GK+ ++G+ PG GQ G Q +G
Sbjct: 1412 GPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRG 1471
Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDY-VPRKAKRKTDRGTDDSPKDSQEDL 129
G G P + + PA +P A R +G + P +
Sbjct: 1472 PPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQ- 1530
Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG 186
E G+ R + + G + DV P PRG GV+G RG
Sbjct: 1531 -----------GEKGEPGRPGDPAVVGPAVAGPKGEKGDV-GPAGPRGATGVQGERG 1575
Score = 29.6 bits (65), Expect = 1.8
Identities = 42/166 (25%), Positives = 56/166 (33%), Gaps = 19/166 (11%)
Query: 36 PDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPR 95
P V G G R + G+PG G+ G ++G G P G P S P +
Sbjct: 2400 PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP---GPPGSVGPPGASGL 2456
Query: 96 AAEKRPAEDYVPRKAKRKTD---RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 152
+K +P + + RG D P S E GDV A
Sbjct: 2457 KGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSA--- 2513
Query: 153 LRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRG-----GGRGQRG 193
+ G + P PRG +G G RG G +G RG
Sbjct: 2514 -----GLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRG 2554
Score = 29.3 bits (64), Expect = 2.3
Identities = 20/76 (26%), Positives = 27/76 (35%), Gaps = 1/76 (1%)
Query: 15 EGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEG 74
+G+P E P G + + G G +G PG GQ+ + G GR
Sbjct: 2206 KGEP-GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGA 2264
Query: 75 EGKPQGEGKPASQAKP 90
GK G P P
Sbjct: 2265 SGKDGDRGSPGVPGSP 2280
Score = 28.5 bits (62), Expect = 4.0
Identities = 24/96 (25%), Positives = 34/96 (35%), Gaps = 4/96 (4%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL- 60
E+ + +G + G+ + P G P G G R +GEPG GQ+
Sbjct: 1297 ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVI 1356
Query: 61 --EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP 94
E G ++G G P G P P P
Sbjct: 1357 GGEGPGLPGRKG-DPGPSGPPGPRGPLGDPGPRGPP 1391
Score = 28.5 bits (62), Expect = 4.0
Identities = 17/57 (29%), Positives = 23/57 (40%)
Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG 70
++G D +P D+G E G G +G+PG G D GS K G
Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605
Score = 27.7 bits (60), Expect = 6.8
Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 26 DEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKP 84
+ G + P G+ G+ + G+PG++GQ G + +G G G P G P
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG-DPGVGVPGSPGPP 2382
Score = 27.7 bits (60), Expect = 6.8
Identities = 17/58 (29%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 35 KPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEG--KPQGEGKPASQAKP 90
+P +G G R ++GE G G+ D G ++G +G G G P S P
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPP 2382
Score = 27.7 bits (60), Expect = 6.8
Identities = 22/99 (22%), Positives = 35/99 (35%), Gaps = 3/99 (3%)
Query: 8 NEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQE 67
++G + G P P EG + +G+ G + D+GE G+ G G
Sbjct: 2657 HKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQP---GPKGDQGEKGERGTPGIGGFPG 2713
Query: 68 KQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYV 106
G G P G + Q + E+ P + V
Sbjct: 2714 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752
Score = 27.3 bits (59), Expect = 8.9
Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
Query: 45 EGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKR-PAE 103
+G++ + GE G GQ+ G GR+ G P Q P S E+ P
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRT---------GAPGPQGPPGSATAKGERGFPGA 1303
Query: 104 DYVPRKAKRKTDRGTDDSP 122
D P R + GT +P
Sbjct: 1304 DGRPGSPGRAGNPGTPGAP 1322
Score = 27.3 bits (59), Expect = 8.9
Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 11/95 (11%)
Query: 6 NKNEGNLENEGKPE---DEVEPDDEGKSDEEEKPDVEGKTECEGK---REDEGEPGDEGQ 59
N ++G + G P D EP G+ P G EGK + G PG G
Sbjct: 2122 NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG 2181
Query: 60 LEDEGSQEKQGRSEGEGKPQG----EGKPASQAKP 90
D G G + G PQG +G+P P
Sbjct: 2182 HGDPGPPGAPGLA-GPAGPQGPSGLKGEPGETGPP 2215
Score = 27.3 bits (59), Expect = 8.9
Identities = 17/55 (30%), Positives = 20/55 (36%)
Query: 24 PDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78
P G+ E KP G+ GK D G PG G G +G G P
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298
Score = 27.3 bits (59), Expect = 8.9
Identities = 32/122 (26%), Positives = 40/122 (32%), Gaps = 10/122 (8%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G + GKP GK + P V G G +GEPG G Q
Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTG----APGQAVV 2303
Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDL 129
G +G+ G A E P A R +P K + G P D ED
Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGE--PGAKGDRG----LPGPRGEKGEAGRAGEPGDPGEDG 2357
Query: 130 QE 131
Q+
Sbjct: 2358 QK 2359
Score = 27.3 bits (59), Expect = 8.9
Identities = 16/57 (28%), Positives = 24/57 (42%)
Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72
G P E + G E+ +P EG G GE G++G + G + +G S
Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/174 (22%), Positives = 83/174 (47%), Gaps = 9/174 (5%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
EK + K E L E + E EP + + EEE+ + E +RE + E + +L
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE-QLRKLERQELRRERQEEEQQQQRLR 301
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR-----KTDR 116
E Q+ + + E E + Q E + Q + E Q E++ + R+ ++ + +R
Sbjct: 302 RE--QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 117 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170
++ +E+ +E+ L E+ +R + R +++LR++Q++ ++R+ Q
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQL-RREQQLRREQQLRREQQLRREQQ 412
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 14/140 (10%)
Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78
E+ E +E + +E + E + E + +RE E E QL E QE++ R + +
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERR--EQQLRRE--QEEERREQQLRRE 367
Query: 79 QGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 138
Q E + Q + E Q R ++ E + R+ + + + Q+ +E+ L E+
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE----------QQLRREQQLRREQ 417
Query: 139 MMRECGDVSRAQEELRKKQK 158
+R + R QEE R +QK
Sbjct: 418 QLRREQQLRREQEEERHEQK 437
Score = 39.7 bits (91), Expect = 0.002
Identities = 32/158 (20%), Positives = 71/158 (44%), Gaps = 10/158 (6%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE--GEPGDEGQLEDEGSQEKQG 70
E + ++E E + +EE+ + + + E E +RE + E +E + + ++++
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130
R E + + + + + Q + E Q R ++ E + R+ + + ++ + +E +
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168
ERH E R + R QEE R W++R+
Sbjct: 432 ERHEQKHEQERREQRLKREQEERR--------DWLKRE 461
Score = 38.9 bits (89), Expect = 0.003
Identities = 34/149 (22%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDE-GEPGDEGQLEDEGSQEKQGR 71
+ E + E ++ ++E + +++E+ + + + E E +RE +E +L+ E+Q R
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 72 SEGEGKPQGEGKPASQAKPESQPRAAE-KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130
E E + + K + + E + R KR E+ + KR+ +R ++ +E L+
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKM 159
+R + RE +V R ++E R++Q++
Sbjct: 600 QR------LKRE--EVERLEQEERREQRL 620
Score = 38.1 bits (87), Expect = 0.005
Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 22/192 (11%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEE-------KPDVEGKTECEGKREDEGEP 54
E+ + + E + + E E + K EEE + + + + E E +RE +
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQ---GEGKPASQAKPESQPRAAEKRPAEDYVPR--K 109
+E +LE E +++ R + E + Q E + Q Q E+R + V R +
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 110 AKRKTDRGTDDSPKDS----------QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159
+R+ R + P++ QE+ +++ L E+ R + R +EE R +Q++
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 160 GGFHWMQRDVQD 171
H +R Q+
Sbjct: 673 KREHEEERREQE 684
Score = 37.7 bits (86), Expect = 0.007
Identities = 32/132 (24%), Positives = 63/132 (47%), Gaps = 12/132 (9%)
Query: 31 DEEEKPDVEGKTEC-EGKREDEG----EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPA 85
DEE++ +GK + +R++E EP D QLE+E Q ++ + + + + EG+
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDR-QLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 86 SQAKPESQPRAAEKRPAEDYVPRKA-KRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECG 144
S+ + + R ++R E + R+ + + +R ++ S + + EE +R
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR-- 212
Query: 145 DVSRAQEELRKK 156
R ELR+K
Sbjct: 213 ---RELLELRRK 221
Score = 37.4 bits (85), Expect = 0.009
Identities = 31/153 (20%), Positives = 66/153 (43%), Gaps = 17/153 (11%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72
+ + + E+ E + EE + + E C+G +E ++ + + ++GR
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRK-AKRKTDRGTDDSPKDSQEDLQE 131
E + Q + E Q R ++ +++ R+ RK + + Q +LQE
Sbjct: 225 EKQ-----------QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 132 -----RHLSSEEMMRECGDVSRAQEELRKKQKM 159
R L +E+ RE + + Q+ LR++Q++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Score = 37.4 bits (85), Expect = 0.009
Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 13/162 (8%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
E L + + E + + + E E+ ++ + + ++E E + +E QL E QE+
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR-RQELERKFREEEQLRQETEQEQ 1739
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 128
R E K E Q +PE + + ++ + + + + +R ++ SQE
Sbjct: 1740 LRRQERYRKILEE----EQLRPEREEQQLRRQERDRKFREEEQLRQER--EEQQLRSQES 1793
Query: 129 LQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170
+R EE +R+ R +++LR +Q+ G + W + +Q
Sbjct: 1794 --DRKFREEEQLRQ----EREEQQLRPQQRDGKYRWEEEQLQ 1829
Score = 37.0 bits (84), Expect = 0.011
Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 5/161 (3%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEG-QL 60
E+ K+E + ++ E D K +EE + + + + + KR+ E E + +L
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 61 EDEGSQEKQGRSEGE-GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 119
E+E +E+Q R E + + Q E + + E + R ++ +E + R+ + + ++
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 120 -DSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 159
+ K +++ +E+ L E+ R D +EE R++Q++
Sbjct: 552 REEEKRLEQERREQRLKREQEERR--DQLLKREEERRQQRL 590
Score = 36.6 bits (83), Expect = 0.015
Identities = 31/149 (20%), Positives = 75/149 (50%), Gaps = 7/149 (4%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRS 72
+ E + E ++ + + + +++ + + + + E + +RE + + + E + +E+Q R
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 73 EGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKA---KRKTDRGTDDSPKDSQEDL 129
E E + + E K + + + R E+R D++ R+ + + +R +D +E+
Sbjct: 428 EQE-EERHEQKHEQERREQRLKREQEER--RDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 130 QERHLSSEEMMRECGDVSRAQEELRKKQK 158
+ER L EE R R +++LR++Q+
Sbjct: 485 RERWLKLEEEERR-EQQERREQQLRREQE 512
Score = 36.6 bits (83), Expect = 0.015
Identities = 31/175 (17%), Positives = 81/175 (46%), Gaps = 9/175 (5%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+P + E + + E+E++ ++E EE + + E + +++DE + +E L
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 62 DE------GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 115
+E +E+Q R E E + + E + + + + E+ + ++ ++
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL- 1094
Query: 116 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 170
++ K +++ + + EE+ +E + R + E R++Q++ + + +VQ
Sbjct: 1095 --REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Score = 36.6 bits (83), Expect = 0.015
Identities = 32/157 (20%), Positives = 74/157 (47%), Gaps = 12/157 (7%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+ + LE + + E+E++ ++E EE + + E + + E+E + +E L
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDS 121
+E +EK+ R E E Q + E + + E++ + ++ +++ +R +
Sbjct: 1126 EE--REKRRRQELE----------RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 122 PKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
+ QE+ Q E+ +E R +EEL+++++
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Score = 35.4 bits (80), Expect = 0.033
Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Query: 17 KPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQG-RSEGE 75
+ E + +E +++EE+ +G E E++ + +L +G +EKQ R E +
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234
Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAK--------RKTDRGTDDSPKDSQE 127
+ E + K E+ R E++ E+ R+ + RK +R + +E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 128 DLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
Q+R +++ R+ + R Q+E R++Q+
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Score = 35.4 bits (80), Expect = 0.033
Identities = 27/158 (17%), Positives = 75/158 (47%), Gaps = 5/158 (3%)
Query: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78
E+E + EEE+ + + + E + +RE + + + E + +E+Q R E + +
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 79 QGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 138
+ + + Q + E + E++ ++ ++ KR+ + D ++ + + E+ ++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 139 MMRECGDVSR-----AQEELRKKQKMGGFHWMQRDVQD 171
+ R+ + R +EE R++Q+ ++R+ ++
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Score = 35.0 bits (79), Expect = 0.043
Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+P + E + + E+E++ ++E EE + + E + + E+E + +E L
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 62 DEGSQ------EKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 113
+E + E+Q R E E + + E + + Q R + R E+ +K K++
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 32.3 bits (72), Expect = 0.28
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 26/168 (15%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKP--------------DVEGKTECEGKREDEG 52
+ E LE K E E E ++ ++EE++ +E + + +
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 53 EPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPR-KAK 111
EGQ + +EK+ R E E + Q E + Q + E Q R D+ + +A+
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR--------DFTWQWQAE 774
Query: 112 RKTDRGTDD-SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
K++RG S + + +ER L +EE R+ + EE K+Q+
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEE--RQQREQRFLPEEEEKEQR 820
Score = 32.3 bits (72), Expect = 0.28
Identities = 35/182 (19%), Positives = 80/182 (43%), Gaps = 30/182 (16%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSD-------EEEKPDVEGKTECEGKREDEGEP 54
E+ Y + E E + + + D++ +SD E+E + K C+G+ ++
Sbjct: 1196 ERQYREEE---ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 55 GDEGQLEDEGSQ--------EKQGRSEGEGKPQGEGK----PASQAKPESQPRAAEKRPA 102
++ QL D SQ E+Q R + + + + + P + + + A++R
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 103 EDYVPR------KAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKK 156
+ + + +++ + TD ++ ++ LQER + + R+ D +EELR +
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER--EEQPLRRQERDRKFREEELRHQ 1370
Query: 157 QK 158
++
Sbjct: 1371 EQ 1372
Score = 32.3 bits (72), Expect = 0.28
Identities = 28/158 (17%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP-GDEGQL 60
++ + ++E L+ + E ++ + + EE+P + + + R D +E QL
Sbjct: 1618 DRKFREDEQLLQE--REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675
Query: 61 EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDD 120
EG +++ R E + K + E + + + E + E++ + RK + + +
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
Query: 121 SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
+ + + R + EE +R R +++LR++++
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRP----EREEQQLRRQER 1769
Score = 31.2 bits (69), Expect = 0.61
Identities = 33/161 (20%), Positives = 65/161 (40%), Gaps = 7/161 (4%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+ + E L E E+ E + +EE + + + E +RE + + + E
Sbjct: 329 EQQEERREQQLRRE--QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDS 121
+ +E+Q R E + + + + + Q + E Q R ++ E R ++ +
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 122 PKDSQED-----LQERHLSSEEMMRECGDVSRAQEELRKKQ 157
K QE+ +E E R + R QEE R+++
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 29.6 bits (65), Expect = 1.8
Identities = 35/162 (21%), Positives = 66/162 (40%), Gaps = 13/162 (8%)
Query: 7 KNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQ 66
+ E L EG+ E ++ + + EE+ + + E E K E + +LE + +
Sbjct: 1670 REEEQLLQEGE-EQQLRRQERDRKFREEEQQLR-RQERERKFLQEEQQLRRQELERKFRE 1727
Query: 67 EKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQ 126
E+Q R E E Q + Q R + E P + +++ R D +
Sbjct: 1728 EEQLRQETE-----------QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 127 EDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRD 168
E L++ + +E R +E+LR++++ QRD
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Score = 28.5 bits (62), Expect = 4.0
Identities = 29/179 (16%), Positives = 81/179 (45%), Gaps = 33/179 (18%)
Query: 13 ENEGKPEDEVEPDDEGKSDEE------EKPDVEGKTECEGKREDEGEPGDEGQL------ 60
E + + +DE++ ++E EE ++ + + + E E ++E+E G+E +
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 61 ------EDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114
E+E QE++ E + + + Q + E + + E++ + ++ +++
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 115 DRG---------------TDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 158
+R ++ K +++L+ ++ EE+ +E + R ++E R++++
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 47.0 bits (110), Expect = 1e-05
Identities = 25/98 (25%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
Query: 6 NKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGK--REDE----GEPGDEGQ 59
N + G + +G+ + D +G+S +PD +G++ GK R+D+ G+P +GQ
Sbjct: 448 NSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQ 507
Query: 60 LEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97
G ++QG+S G+P +G+ + ++ + Q +++
Sbjct: 508 SSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS 545
Score = 42.4 bits (98), Expect = 3e-04
Identities = 19/89 (21%), Positives = 47/89 (52%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
+G + G+P+ + + G++D +++ G+TE +G+ + +GQ G ++
Sbjct: 373 QGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQPRAA 97
QG+S G+P +G+ + + + Q +++
Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSS 461
Score = 42.4 bits (98), Expect = 3e-04
Identities = 19/85 (22%), Positives = 44/85 (51%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
+G + G+P+ + + G++D + + G+T+ +G+ +P +GQ G ++
Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDR 492
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQ 93
Q +S G+P G+G+ + + + Q
Sbjct: 493 QDQSYHYGQPDGQGQSSHYGQTDRQ 517
Score = 39.7 bits (91), Expect = 0.002
Identities = 20/88 (22%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G E +G+ + D +G+ G+T+ +G+ G+P +GQ G ++Q
Sbjct: 404 GQTERQGQSSHYSQMDRQGQGSHY------GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQ 457
Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAA 97
G+S G+ +G+ + ++P+ Q +++
Sbjct: 458 GQSSHYGQTDRQGQSSHYSQPDKQGQSS 485
Score = 37.4 bits (85), Expect = 0.009
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
Query: 12 LENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQ----- 66
++ +G+ + D +G+S +PD +G+ G+ + +G+ GQ + +G
Sbjct: 418 MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQ 477
Query: 67 -EKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97
+KQG+S GK + + +P+ Q +++
Sbjct: 478 PDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSS 509
Score = 35.4 bits (80), Expect = 0.033
Identities = 15/68 (22%), Positives = 36/68 (52%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G + +G+ +PD +G+S + D +G++ G+ + +G+ GQ + +G
Sbjct: 512 GQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHY 571
Query: 70 GRSEGEGK 77
G+++ +G+
Sbjct: 572 GQTDRQGQ 579
Score = 35.0 bits (79), Expect = 0.043
Identities = 19/95 (20%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 5 YNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEG 64
Y+ ++ N + +G + P+ +G+S +PD + ++ G+ + + + GQ E +G
Sbjct: 353 YHYDQTNRQGQGSHYSQ--PNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQG 410
Query: 65 SQ------EKQGRSEGEGKPQGEGKPASQAKPESQ 93
++QG+ G+ +G+ + +P+ Q
Sbjct: 411 QSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
Score = 34.7 bits (78), Expect = 0.056
Identities = 18/85 (21%), Positives = 41/85 (48%)
Query: 9 EGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEK 68
+G + GK + + + G+ D + + G+T+ +G+ G+P +GQ ++
Sbjct: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
Query: 69 QGRSEGEGKPQGEGKPASQAKPESQ 93
QG+S G+ +G+ + + + Q
Sbjct: 541 QGQSSHYGQTDRQGQSSHYGQTDRQ 565
Score = 33.9 bits (76), Expect = 0.095
Identities = 18/94 (19%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGE------PGDEGQLEDE 63
G + +G+ + D +G+S +PD +G++ G+ + +G+ +GQ
Sbjct: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97
+QG+S G+P + + + + + Q +++
Sbjct: 368 SQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSS 401
Score = 33.9 bits (76), Expect = 0.095
Identities = 16/80 (20%), Positives = 39/80 (48%)
Query: 10 GNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQ 69
G + +G+ + D +G+S +PD +G++ + + +G+ GQ + +G
Sbjct: 500 GQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHY 559
Query: 70 GRSEGEGKPQGEGKPASQAK 89
G+++ +G+ G+ Q +
Sbjct: 560 GQTDRQGQSYHYGQTDRQGQ 579
Score = 32.7 bits (73), Expect = 0.21
Identities = 37/182 (20%), Positives = 73/182 (40%), Gaps = 24/182 (13%)
Query: 14 NEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEG----SQEKQ 69
+ G+PE + G+S+++++ + E R+D ++ + +D+ E+Q
Sbjct: 145 HHGQPERQDRDSHHGQSEKQDRDSHHSQPE----RQDRDSHHNQSERQDKDFSFDQSERQ 200
Query: 70 GRSEGEGKPQGEGKPASQAKPESQPRAAEK--RPAEDYVPRKAKRKTDRGTDDSPKDSQE 127
+ GK + QAK + A + +P +D +++R T + S+
Sbjct: 201 SQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT--------QQSET 252
Query: 128 DLQERHLSSEEMMRE---CGDVSRAQEEL---RKKQKMGGFHWMQRDVQDPFAPRGQRGV 181
Q H + + CG R +EL + ++ H+ Q D QD GQ
Sbjct: 253 LGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDR 312
Query: 182 RG 183
+G
Sbjct: 313 QG 314
Score = 30.4 bits (67), Expect = 1.0
Identities = 26/132 (19%), Positives = 54/132 (40%), Gaps = 13/132 (9%)
Query: 6 NKNEGNLENEGKPEDEVEPDDE--GKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDE 63
NK+ G ++ + E D + G + + + E + + + E + GD
Sbjct: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS----HH 146
Query: 64 GSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 123
G E+Q R G+ + + + + ++PE Q R + +E ++ D D S +
Sbjct: 147 GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE-------RQDKDFSFDQSER 199
Query: 124 DSQEDLQERHLS 135
SQ+ + +S
Sbjct: 200 QSQDSSSGKKVS 211
Score = 30.0 bits (66), Expect = 1.4
Identities = 34/172 (19%), Positives = 71/172 (41%), Gaps = 13/172 (7%)
Query: 16 GKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGE 75
G+ + + + G++D +++ G+T+ +G+ + +GQ ++QG+S
Sbjct: 284 GQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHY 343
Query: 76 GKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDS----QEDLQE 131
G+ +G+ + Q + + P + + + G D+ S Q D Q+
Sbjct: 344 GQMDRKGQCYHYDQTNRQGQGSHYSQ-----PNRQGQSSHYGQPDTQDQSSHYGQTDRQD 398
Query: 132 RHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRG 183
+ + R+ G S + R+ Q G H+ Q D Q + GQ +G
Sbjct: 399 QSSHYGQTERQ-GQSSHYSQMDRQGQ---GSHYGQTDRQGQSSHYGQPDRQG 446
Score = 30.0 bits (66), Expect = 1.4
Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 13 ENEGKPEDEVEPDDEGKSDEEEKPDVEG------KTECEGKREDEGEPGDEGQLEDEGSQ 66
+ +G+ +PD +G+S + D +G +T +G+ +P +GQ G
Sbjct: 323 DRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQP 382
Query: 67 EKQGRSEGEGKPQGEGKPASQAKPESQPRAA 97
+ Q +S G+ + + + + E Q +++
Sbjct: 383 DTQDQSSHYGQTDRQDQSSHYGQTERQGQSS 413
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 46.6 bits (109), Expect = 1e-05
Identities = 43/166 (25%), Positives = 75/166 (45%), Gaps = 14/166 (8%)
Query: 12 LENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQL-EDEGSQEKQG 70
L +P +E E + + + D KTE E + E+E E DE + +DEG + ++
Sbjct: 239 LSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREA 298
Query: 71 RSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 130
E K +GE P + KPE ++RP ++ + R T SQE+ +
Sbjct: 299 PILKEFKEEGEEIP--RVKPEEM---MDERPKTRSQEQEVLERGGRFT-----RSQEEAR 348
Query: 131 ERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPR 176
+ HL+ ++ +E S +EE R+ + G ++ + P PR
Sbjct: 349 KSHLARQQQEKEMKTTSPLEEEEREIKSSQG---LKEKSKSPSPPR 391
Score = 28.1 bits (61), Expect = 5.2
Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 14/171 (8%)
Query: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTEC------EGKREDEGEP 54
+EK LE E + E+E DE P EG E E
Sbjct: 141 LEKQQELLRQRLEREAREAAELEEASAESEDEMIHP--EGVASLLPPDFQSSLERPELEL 198
Query: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEG-----KPASQAKPESQPRAAEKRPAEDYVPRK 109
+ E++G S+ E +GE + A AK + AE+ ++ R
Sbjct: 199 SRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRN 258
Query: 110 AKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMG 160
+ + DR ++ +E+ +E EE E G SR L++ ++ G
Sbjct: 259 LRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDE-GQKSREAPILKEFKEEG 308
Score = 28.1 bits (61), Expect = 5.2
Identities = 19/93 (20%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Query: 2 EKPYNKNEGNLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLE 61
E+ + E E + + E E E + + + E++ + + + E +RE E + GD +
Sbjct: 1247 EREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR-- 1304
Query: 62 DEGSQEKQGRSEGEGKPQGEGKPASQAKPESQP 94
++ R G + + + K S+++ S P
Sbjct: 1305 ----DRERDRERGRERDRRDTKRHSRSRSRSTP 1333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.130 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,459,812
Number of Sequences: 37866
Number of extensions: 652275
Number of successful extensions: 16576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 631
Number of HSP's successfully gapped in prelim test: 693
Number of HSP's that attempted gapping in prelim test: 4138
Number of HSP's gapped (non-prelim): 7388
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.