Guide to the Human Genome
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Search of human proteins with 5453920

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]
         (467 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]         971   0.0  
gi|10835000 pancreatic lipase precursor [Homo sapiens]                675   0.0  
gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]       640   0.0  
gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]       445   e-125
gi|21245106 lipase, member H precursor [Homo sapiens]                 197   2e-50
gi|4557727 lipoprotein lipase precursor [Homo sapiens]                194   1e-49
gi|5174497 endothelial lipase precursor [Homo sapiens]                192   7e-49
gi|194097335 lipase C precursor [Homo sapiens]                        183   3e-46
gi|39752679 lipase, member I [Homo sapiens]                           172   6e-43
gi|7706661 phospholipase A1 member A [Homo sapiens]                   152   5e-37
gi|118572606 hemicentin 1 [Homo sapiens]                               30   4.7  
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     30   6.1  
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]              30   6.1  

>gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]
          Length = 467

 Score =  971 bits (2511), Expect = 0.0
 Identities = 467/467 (100%), Positives = 467/467 (100%)

Query: 1   MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT 60
           MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT
Sbjct: 1   MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT 60

Query: 61  NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120
           NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC
Sbjct: 61  NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120

Query: 121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA 180
           ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA
Sbjct: 121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA 180

Query: 181 GSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMG 240
           GSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMG
Sbjct: 181 GSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMG 240

Query: 241 HLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAA 300
           HLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAA
Sbjct: 241 HLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAA 300

Query: 301 YPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGV 360
           YPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGV
Sbjct: 301 YPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGV 360

Query: 361 SITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLW 420
           SITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLW
Sbjct: 361 SITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLW 420

Query: 421 NNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC 467
           NNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC
Sbjct: 421 NNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC 467


>gi|10835000 pancreatic lipase precursor [Homo sapiens]
          Length = 465

 Score =  675 bits (1742), Expect = 0.0
 Identities = 315/468 (67%), Positives = 377/468 (80%), Gaps = 4/468 (0%)

Query: 1   MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT 60
           ML  WT++L LLGA  GKEVCYE LGCFSD  PW G   RPL ILPWSP+ + TRFLLYT
Sbjct: 1   MLPLWTLSL-LLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYT 59

Query: 61  NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120
           NENPNNFQ +  +D S+I  SNF+ +RKTRFIIHGFIDKG+E+W+ ++CK LF+VE VNC
Sbjct: 60  NENPNNFQEVA-ADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNC 118

Query: 121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA 180
           ICVDWK GS+  YTQA+ N+R+VGA+VA  ++ L + + Y PS VH+IGHSLGAH AGEA
Sbjct: 119 ICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEA 178

Query: 181 GSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQM 239
           G +T G + RITGLDP E  F+ TPE VRLDPSDA FVDVIHTD AP++P LGFG +Q +
Sbjct: 179 GRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVV 238

Query: 240 GHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFA 299
           GHLDFFPNGG  MPGCKKN LSQIVD+DGIW GTRDF ACNHLRSYKYY +SI+NPDGFA
Sbjct: 239 GHLDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFA 298

Query: 300 AYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYG 359
            +PC SY  F ++KCFPCP  GCPQMGHYAD++ G+T++  QKF+L+TG+ASNFARWRY 
Sbjct: 299 GFPCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYK 358

Query: 360 VSITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFL 419
           VS+TLSG+  TG I V+LFGNKGN+ QY IF+G LKP STHS EFD+ +DVG ++ VKF+
Sbjct: 359 VSVTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFI 418

Query: 420 WNNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC 467
           W NNVINPTLP+VGA+KI V+    K  +NFCS +TVRE+ LLTLTPC
Sbjct: 419 WYNNVINPTLPRVGASKIIVETNVGKQ-FNFCSPETVREEVLLTLTPC 465


>gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]
          Length = 470

 Score =  640 bits (1651), Expect = 0.0
 Identities = 294/469 (62%), Positives = 361/469 (76%), Gaps = 2/469 (0%)

Query: 1   MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT 60
           ML  WT+ L LL   +GKEVCY  LGCFSD +PW GT  RP+K+LPWSPE I TRFLLYT
Sbjct: 2   MLPPWTLGLLLLATVRGKEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYT 61

Query: 61  NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120
           NENPNNFQ++  ++P TIEASNFQ+DRKTRFIIHGF+DK ++SW +DMCKK+FEVE+VNC
Sbjct: 62  NENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMFEVEKVNC 121

Query: 121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA 180
           ICVDW+ GS+A YTQA  N+RVVGA+ A ++  L T+  Y    VH+IGHSLGAH A EA
Sbjct: 122 ICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEA 181

Query: 181 GSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQM 239
           G +  G + RITGLDP    F+  PEEVRLDPSDA FVDVIHTD++P++P LGFG +Q++
Sbjct: 182 GRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKV 241

Query: 240 GHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFA 299
           GHLDFFPNGG+ MPGCKKN LS I D+DGIW G   FV+CNHLRS++YY  S+LNPDGF 
Sbjct: 242 GHLDFFPNGGKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSFEYYSSSVLNPDGFL 301

Query: 300 AYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYG 359
            YPC SY  F+  KCFPCP +GCP+MGHYAD+F G+TS  +Q FFLNTGE+ NF  WRY 
Sbjct: 302 GYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFFLNTGESGNFTSWRYK 361

Query: 360 VSITLSGR-TATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKF 418
           VS+TLSG+    G I++AL+G+  N+ QY IF+G LKP ++H+   D   +VG I+KVKF
Sbjct: 362 VSVTLSGKEKVNGYIRIALYGSNENSKQYEIFKGSLKPDASHTCAIDVDFNVGKIQKVKF 421

Query: 419 LWNNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC 467
           LWN   IN + PK+GA++ITVQ GE+ T YNFCS DTV E+ L +L PC
Sbjct: 422 LWNKRGINLSEPKLGASQITVQSGEDGTEYNFCSSDTVEENVLQSLYPC 470


>gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]
          Length = 467

 Score =  445 bits (1145), Expect = e-125
 Identities = 228/470 (48%), Positives = 299/470 (63%), Gaps = 6/470 (1%)

Query: 1   MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT 60
           ML  W +     G ++GKEVCYE LGCF D  PW  T    L  LPWSPEKI TRFLLYT
Sbjct: 1   MLGIWIVAFLFFGTSRGKEVCYERLGCFKDGLPWTRTFSTELVGLPWSPEKINTRFLLYT 60

Query: 61  NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC 120
             NPN +Q +   + STI+AS F  D+ TR  I G+  K D  W  DMC  L ++E++NC
Sbjct: 61  IHNPNAYQEISAVNSSTIQASYFGTDKITRINIAGW--KTDGKWQRDMCNVLLQLEDINC 118

Query: 121 ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA 180
           I +DW  GS+  Y  A NN+RVVGA+VA  +D+L+ ++ Y PSKVHLIGHSLGAH+AGEA
Sbjct: 119 INLDWINGSRE-YIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEA 177

Query: 181 GSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMG 240
           GS+ PGL RITGLDP    F +TP+EVRLDPSDA+FVDVIHT+AA ++  LG GT    G
Sbjct: 178 GSRIPGLGRITGLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACG 237

Query: 241 HLDFFPNGGESMPGCKKNALSQI-VDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFA 299
           HLDF+PNGG+ MPGC+      +  + +        F  CNH RSY++Y ESILNPD F 
Sbjct: 238 HLDFYPNGGKHMPGCEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESILNPDAFI 297

Query: 300 AYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQ-QKFFLNTGEASNFARWRY 358
           AYPC SY SF++  CF C  +GCP MGH+AD+F  +  +     +FLNTG  S FARWR+
Sbjct: 298 AYPCRSYTSFKAGNCFFCSKEGCPTMGHFADRFHFKNMKTNGSHYFLNTGSLSPFARWRH 357

Query: 359 GVSITLSGRTAT-GQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVK 417
            +S+ LSG   T G + + + G    T +++I  G L+PG T++   DA ++VG I  V+
Sbjct: 358 KLSVKLSGSEVTQGTVFLRVGGAVRKTGEFAIVSGKLEPGMTYTKLIDADVNVGNITSVQ 417

Query: 418 FLWNNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC 467
           F+W  ++   +  K+GA  +    G+      FCS+D +  + L  L PC
Sbjct: 418 FIWKKHLFEDSQNKLGAEMVINTSGKYGYKSTFCSQDIMGPNILQNLKPC 467


>gi|21245106 lipase, member H precursor [Homo sapiens]
          Length = 451

 Score =  197 bits (500), Expect = 2e-50
 Identities = 125/351 (35%), Positives = 174/351 (49%), Gaps = 39/351 (11%)

Query: 52  IGTRFLLYTNENPNNFQILLLSDPSTIEAS---NFQMDRKTRFIIHGFIDKGDES-WVTD 107
           +  R +LYT +N        L+   TI +S   N  + +KT FI+HGF   G    W+ D
Sbjct: 39  LNVRLMLYTRKN--------LTCAQTINSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDD 90

Query: 108 MCKKLFEVEEVNCICVDWKKGSQAT-YTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVH 166
           + K L  VE++N + VDW +G+    YT A++  R V   + + +D +L E +     ++
Sbjct: 91  LVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGA-SLDDIY 149

Query: 167 LIGHSLGAHVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAA 225
           +IG SLGAH++G  G    G L RITGLDP    F   P + RLDPSDA FVDVIH+D  
Sbjct: 150 MIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTD 209

Query: 226 PLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSY 285
            L      G  + +G++DF+PNGG   PGC K  L           G   +  C+H RS 
Sbjct: 210 AL------GYKEPLGNIDFYPNGGLDQPGCPKTIL-----------GGFQYFKCDHQRSV 252

Query: 286 KYYLESILNPDGFAAYPCTSYKSFESDKCFPC---PDQGCPQMGHYADKFAGR---TSEE 339
             YL S+       AYPC SY+ + + KC  C     + CP +G+YAD +          
Sbjct: 253 YLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWKDHLRGKDPP 312

Query: 340 QQKFFLNTGEASNFARWRYGVS-ITLSGRTATGQIKVALFGNKGNTHQYSI 389
             K F +T E S F  + Y V  IT +     G I + L    GNT +  I
Sbjct: 313 MTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKI 363


>gi|4557727 lipoprotein lipase precursor [Homo sapiens]
          Length = 475

 Score =  194 bits (493), Expect = 1e-49
 Identities = 132/419 (31%), Positives = 205/419 (48%), Gaps = 19/419 (4%)

Query: 52  IGTRFLLYTNENPNNFQILLLSDPS-TIEASNFQMDRKTRFIIHGFIDKGD-ESWVTDMC 109
           I ++F L T E+       L+   + ++   +F    KT  +IHG+   G  ESWV  + 
Sbjct: 37  IESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLV 96

Query: 110 KKLFEVE-EVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLI 168
             L++ E + N I VDW   +Q  Y  +A   ++VG  VA+ ++ +  E++YP   VHL+
Sbjct: 97  AALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLL 156

Query: 169 GHSLGAHVAGEAGSKT-PGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPL 227
           G+SLGAH AG AGS T   ++RITGLDP   +FE      RL P DADFVDV+HT     
Sbjct: 157 GYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRG- 215

Query: 228 IPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKY 287
            P    G  + +GH+D +PNGG   PGC      +++   G+       V C+H RS   
Sbjct: 216 SPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGL-GDVDQLVKCSHERSIHL 274

Query: 288 YLESILNPDG-FAAYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLN 346
           +++S+LN +    AY C+S ++FE   C  C    C  +G+  +K   + S    K +L 
Sbjct: 275 FIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRS---SKMYLK 331

Query: 347 TGEASNFARWRYGVSITLSG---RTATGQ-IKVALFGNKGNTHQYSIFRGILKPGSTHSY 402
           T     +  + Y V I  SG    T T Q  +++L+G    +         +    T+S+
Sbjct: 332 TRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSF 391

Query: 403 EFDAKLDVGTIEKVKFLWNNNVINP-----TLPKVGATKITVQKGEEKTVYNFCSEDTV 456
               ++D+G +  +K  W ++         + P     KI V+ GE +    FCS + V
Sbjct: 392 LIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKV 450


>gi|5174497 endothelial lipase precursor [Homo sapiens]
          Length = 500

 Score =  192 bits (487), Expect = 7e-49
 Identities = 137/431 (31%), Positives = 207/431 (48%), Gaps = 37/431 (8%)

Query: 51  KIGTRFLLYTNENPNNFQILL-LSDPSTIEASNFQMDRKTRFIIHGFIDKGD-ESWVTDM 108
           K   RF L T+++P +    L +     +E  +F M  KT FIIHG+   G  E+W+  +
Sbjct: 46  KPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKL 105

Query: 109 CKKLFEVE-EVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHL 167
              L   E + N + VDW   +   YT A NN RVVG  +A+MLD L  +  +    VHL
Sbjct: 106 VSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHL 165

Query: 168 IGHSLGAHVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAP 226
           IG+SLGAHVAG AG+   G + RITGLDP    FE      RL P DADFVDV+HT    
Sbjct: 166 IGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRS 225

Query: 227 LIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGT-RDFVACNHLRSY 285
               L  G    +GH+D +PNGG+  PGC  N +     L  I  GT  + V C H R+ 
Sbjct: 226 F--GLSIGIQMPVGHIDIYPNGGDFQPGCGLNDV-----LGSIAYGTITEVVKCEHERAV 278

Query: 286 KYYLESILNPDGFA-AYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFF 344
             +++S++N D  + A+ CT    F+   C  C    C  +G+ A K     ++   K +
Sbjct: 279 HLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKM---RNKRNSKMY 335

Query: 345 LNTGEASNFARWRYGVSITLSGRTATGQIK----VALFGNKGNTHQYSI-FRGILKPGST 399
           L T     F  + Y + I +      G+I+    V L+G   ++    +     ++  +T
Sbjct: 336 LKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNAT 395

Query: 400 HSYEFDAKLDVGTIEKVKFLW--------------NNNVINPTLP--KVGATKITVQKGE 443
           +++    + D+G + K++  W               + +  P  P  ++   +I V+ GE
Sbjct: 396 NTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGE 455

Query: 444 EKTVYNFCSED 454
            +    FC+ED
Sbjct: 456 TQRKLTFCTED 466


>gi|194097335 lipase C precursor [Homo sapiens]
          Length = 499

 Score =  183 bits (464), Expect = 3e-46
 Identities = 150/470 (31%), Positives = 213/470 (45%), Gaps = 42/470 (8%)

Query: 25  LGCFSDTEPWG--GTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASN 82
           LG     EP+G    A+   K L     ++ TRFLL+   N    QI + + P T++   
Sbjct: 23  LGQSLKPEPFGRRAQAVETNKTL----HEMKTRFLLFGETN-QGCQIRI-NHPDTLQECG 76

Query: 83  FQMDRKTRFIIHGF-IDKGDESWVTDMCKKLFE--VEEVNCICVDWKKGSQATYTQAANN 139
           F        IIHG+ +D   E+W+  M   L     + VN   VDW   +   YT A  N
Sbjct: 77  FNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRN 136

Query: 140 VRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPG---LSRITGLDPV 196
            R+VG +VA +L  L        S VHLIG+SLGAHV+G AGS   G   + RITGLD  
Sbjct: 137 TRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAA 196

Query: 197 EASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCK 256
              FE +    RL P DA+FVD IHT     +  L  G  Q +GH DF+PNGG   PGC 
Sbjct: 197 GPLFEGSAPSNRLSPDDANFVDAIHTFTREHMG-LSVGIKQPIGHYDFYPNGGSFQPGCH 255

Query: 257 KNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFA-AYPCTSYKSFESDKCF 315
              L + +   G  A T+  + C+H RS   +++S+L+    + AYPC    SF    C 
Sbjct: 256 FLELYRHIAQHGFNAITQT-IKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCL 314

Query: 316 PCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGVSITLSGRTAT---GQ 372
            C    C  +G++  +       + ++ FL T   S F  + Y   I    +T T     
Sbjct: 315 SCKKGRCNTLGYHVRQ---EPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTT 371

Query: 373 IKVALFGNKGNTHQYSIFRGI-LKPGSTHSYEFDAKLDVGTIEKVKFLWNNNVI------ 425
             ++L G K    +  I  G  +    T+S+     +D+G +  +KF W N+ +      
Sbjct: 372 FTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWD 431

Query: 426 ----------NPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLT 465
                      P    +    I V+ GE +    FCSE+T  +D LL  T
Sbjct: 432 TVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENT--DDLLLRPT 479


>gi|39752679 lipase, member I [Homo sapiens]
          Length = 481

 Score =  172 bits (436), Expect = 6e-43
 Identities = 109/330 (33%), Positives = 163/330 (49%), Gaps = 32/330 (9%)

Query: 51  KIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGD-ESWVTDMC 109
           +I T  ++YT  N N  + L   + S     NF   +KT ++IHG+   G    W+ +  
Sbjct: 61  RIETILMMYTRNNLNCAEPLFEQNNSL--NVNFNTQKKTVWLIHGYRPVGSIPLWLQNFV 118

Query: 110 KKLFEVEEVNCICVDWKKGSQA-TYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLI 168
           + L   E++N I VDW +G+    Y +A  N R V   ++  +  LL ++       H I
Sbjct: 119 RILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLL-KHGASLDNFHFI 177

Query: 169 GHSLGAHVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPL 227
           G SLGAH++G  G    G L RITGLDP    F   P   RLD +DA FVDVIH+D+   
Sbjct: 178 GVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSN-- 235

Query: 228 IPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKY 287
               G G  + +GH+DF+PNGG   PGC K+  S I            F+ CNH R+   
Sbjct: 236 ----GLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGI-----------QFIKCNHQRAVHL 280

Query: 288 YLESILNPDGFAAYPCTSYKSFESDKCFPC---PDQGCPQMGHYADKFAGRTSEEQQ--- 341
           ++ S+     F ++PC SYK +++  C  C    ++ CP++G+ A  F G   E  +   
Sbjct: 281 FMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRP 340

Query: 342 ---KFFLNTGEASNFARWRYGVSITLSGRT 368
                FL+T     F  + + +SI +  +T
Sbjct: 341 LRTTVFLDTSGTYPFCTYYFVLSIIVPDKT 370


>gi|7706661 phospholipase A1 member A [Homo sapiens]
          Length = 456

 Score =  152 bits (385), Expect = 5e-37
 Identities = 97/277 (35%), Positives = 137/277 (49%), Gaps = 25/277 (9%)

Query: 55  RFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDE-SWVTDMCKKLF 113
           +FLL+   NP+  Q  L+   S ++ S F     T+ IIHGF   G + SW+    + L 
Sbjct: 52  QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLL 109

Query: 114 EVEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLG 173
                N I VDW  GS   Y  A  NV  +  +++  L+ LL       S +H+IG SLG
Sbjct: 110 RATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKLLV-LGVSESSIHIIGVSLG 168

Query: 174 AHVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLG 232
           AHV G  G    G L +ITGLDP    +     E RLD  DA FV+ IHTD   L     
Sbjct: 169 AHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNL----- 223

Query: 233 FGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESI 292
            G    +GH+D+F NGG+  PGC              +AG   ++ C+H+R+   Y+ ++
Sbjct: 224 -GIRIPVGHVDYFVNGGQDQPGCPTF----------FYAGY-SYLICDHMRAVHLYISAL 271

Query: 293 LNPDGFAAYPCTSYKSFESDKCFPCPDQ---GCPQMG 326
            N     A+PC SYK+F + +C  C +     CP++G
Sbjct: 272 ENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIG 308


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 76   STIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNCICVD 124
            S++E+   Q++    F IH  I KGD S   + C   F ++ V   C D
Sbjct: 5062 SSVESDYNQIEETLGFKIHASISKGDRS---NQCPSGFTLDSVGPFCAD 5107


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 14/90 (15%)

Query: 185 PGLSRITGLDPVEASFESTPEEV---RLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGH 241
           P LS++T L  VE    ST E+      DP D+     +H  + P  PF     N     
Sbjct: 584 PELSQLTALRSVELEESSTDEDFFQSSTDPKDSSLPGDLHVTSGPESPF-----NNIFND 638

Query: 242 LDFFPNGGESMPGCKKNALSQIVDLDGIWA 271
           +D      E +P  +K  +  +++L+G+ A
Sbjct: 639 VD----KSEDLPSHQK--IFDLMELNGVQA 662


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 8/67 (11%)

Query: 256 KKNALSQIVDLDGIWAGTRDFVACNHLRSYKYY--------LESILNPDGFAAYPCTSYK 307
           K N L Q   L GI+   R        R ++ Y        L+ ++ P G++AY C    
Sbjct: 275 KSNELPQANRLPGIFDDVRGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGEC 334

Query: 308 SFESDKC 314
           SF  D C
Sbjct: 335 SFPLDSC 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,690,541
Number of Sequences: 37866
Number of extensions: 852760
Number of successful extensions: 1884
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1833
Number of HSP's gapped (non-prelim): 14
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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