Guide to the Human Genome
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Search of human proteins with 4758074

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758074 crystallin, beta B3 [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758074 crystallin, beta B3 [Homo sapiens]                         447   e-126
gi|4503061 crystallin, beta B1 [Homo sapiens]                         253   1e-67
gi|4503063 crystallin, beta B2 [Homo sapiens]                         246   1e-65
gi|12056461 crystallin, beta A3 [Homo sapiens]                        170   7e-43
gi|4503059 crystallin, beta A4 [Homo sapiens]                         146   1e-35
gi|16936542 crystallin, beta A2 [Homo sapiens]                        144   5e-35
gi|16936540 crystallin, beta A2 [Homo sapiens]                        144   5e-35
gi|7019357 crystallin, beta A2 [Homo sapiens]                         144   5e-35
gi|8922120 crystallin, gamma S [Homo sapiens]                         120   6e-28
gi|10518338 crystallin, gamma C [Homo sapiens]                        118   4e-27
gi|148491074 crystallin, gamma B [Homo sapiens]                       112   2e-25
gi|148491057 crystallin, gamma A [Homo sapiens]                       112   2e-25
gi|13377002 crystallin, gamma D [Homo sapiens]                        106   2e-23
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi...   104   5e-23
gi|89886227 absent in melanoma 1-like [Homo sapiens]                  103   8e-23
gi|62988361 absent in melanoma 1 [Homo sapiens]                        93   1e-19
gi|21389517 gammaN-crystallin [Homo sapiens]                           91   7e-19
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]    28   4.4  
gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho...    28   5.7  
gi|239750232 PREDICTED: hypothetical protein XP_002347325 [Homo ...    28   5.7  
gi|118918417 testis specific protein, Y-linked 2 [Homo sapiens]        28   5.7  
gi|223633988 hypothetical protein LOC85379 [Homo sapiens]              28   7.4  
gi|239758109 PREDICTED: hypothetical protein [Homo sapiens]            28   7.4  
gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo ...    28   7.4  
gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]          28   7.4  
gi|90186264 ankyrin repeat domain 55 isoform 2 [Homo sapiens]          28   7.4  
gi|239747006 PREDICTED: similar to testis specific protein, Y-li...    27   9.7  
gi|239746996 PREDICTED: similar to Testis-specific Y-encoded pro...    27   9.7  
gi|118026929 testis specific protein, Y-linked 3 [Homo sapiens]        27   9.7  

>gi|4758074 crystallin, beta B3 [Homo sapiens]
          Length = 211

 Score =  447 bits (1149), Expect = e-126
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ 60
           MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
Sbjct: 1   MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ 60

Query: 61  VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE 120
           VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
Sbjct: 61  VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE 120

Query: 121 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH 180
           NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
Sbjct: 121 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH 180

Query: 181 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS 211
           WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
Sbjct: 181 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS 211


>gi|4503061 crystallin, beta B1 [Homo sapiens]
          Length = 252

 Score =  253 bits (645), Expect = 1e-67
 Identities = 107/188 (56%), Positives = 142/188 (75%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           G+Y+++++ELENFQG+R E S EC +L D   ++V SI V +GPW+AFE   FRGE F+L
Sbjct: 57  GNYRLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFIL 116

Query: 82  EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141
           EKG+YPRW+ WS+S  SD L+S RP+ +D+  HK+ LFE   F G  +EI  DD PSLW 
Sbjct: 117 EKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWV 176

Query: 142 HGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQK 201
           +GF DRV SV+  +GTWVGY++PGYRG QY+ E G++RHWNEW A QPQ+QS+RR+RD++
Sbjct: 177 YGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQ 236

Query: 202 WHKRGRFP 209
           WH  G FP
Sbjct: 237 WHLEGSFP 244


>gi|4503063 crystallin, beta B2 [Homo sapiens]
          Length = 205

 Score =  246 bits (628), Expect = 1e-65
 Identities = 106/187 (56%), Positives = 149/187 (79%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+I++E ENFQG   EL+  CP+L ++ +EK GS+ V++GPW+ +E    +GEQFV EKG
Sbjct: 18  KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
           +YPRWD+W++SR +DSL SLRP+ +DS  HK+ L+ENP F+G+KMEI+DDDVPS  AHG+
Sbjct: 78  EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137

Query: 145 QDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204
           Q++V+SVR  +GTWVGY++PGYRG QY+ E+G+Y+  +++ A  PQ+QSVRRIRD +WH+
Sbjct: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQ 197

Query: 205 RGRFPSS 211
           RG F  S
Sbjct: 198 RGAFHPS 204



 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 29/65 (44%), Positives = 43/65 (66%), Gaps = 2/65 (3%)

Query: 24  YKVILYELENFQGKRCE-LSAECPSL-TDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           +K+ILYE  NF GK+ E +  + PS       EKV S++V+SG W+ ++   +RG Q++L
Sbjct: 107 HKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLL 166

Query: 82  EKGDY 86
           EKGDY
Sbjct: 167 EKGDY 171


>gi|12056461 crystallin, beta A3 [Homo sapiens]
          Length = 215

 Score =  170 bits (431), Expect = 7e-43
 Identities = 84/187 (44%), Positives = 125/187 (66%), Gaps = 11/187 (5%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           G +K+ +Y+ ENFQGKR E ++ CP++++   + V S++VESG W+ +E  +F G+QF+L
Sbjct: 29  GPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFIL 88

Query: 82  EKGDYPRWDAW--SNSRDSDSLLSLRPL-NIDSPHHKLHLFENPAFSGRKMEIVDDDVPS 138
           E+G+YPRWDAW  SN+   + L+S RP+ + +    K+ +FE   F GR+ EI  DD PS
Sbjct: 89  ERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEI-SDDYPS 147

Query: 139 LWAHG-FQDRVASVRAINGTWVGYEFPGYRGRQYVFE----RGEYRHWNEW--DASQPQL 191
           L A G F + V S++  +G WV Y++PGYRG QY+ E     G+Y+HW EW   A   Q+
Sbjct: 148 LQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQI 207

Query: 192 QSVRRIR 198
           QS+RRI+
Sbjct: 208 QSIRRIQ 214


>gi|4503059 crystallin, beta A4 [Homo sapiens]
          Length = 196

 Score =  146 bits (369), Expect = 1e-35
 Identities = 78/187 (41%), Positives = 119/187 (63%), Gaps = 11/187 (5%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           G +K+++++ + FQG+R E +AECPS+ +   E V S++V SG W+ FE   F+G+Q++L
Sbjct: 10  GPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYIL 69

Query: 82  EKGDYPRWDAW--SNSRDSDSLLSLRPLN-IDSPHHKLHLFENPAFSGRKMEIVDDDVPS 138
           E+G+YP WDAW  + +  ++ L S RP    +    +L +FE   F G+K E+  DD PS
Sbjct: 70  ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGEL-SDDYPS 128

Query: 139 LWAHGFQ-DRVASVRAINGTWVGYEFPGYRGRQYVFE----RGEYRHWNEWDASQP--QL 191
           L A G++ + V S    +G WV  +FPGYRG QYV E     G+Y+H+ EW +  P  Q+
Sbjct: 129 LQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQV 188

Query: 192 QSVRRIR 198
           QS+RRI+
Sbjct: 189 QSIRRIQ 195


>gi|16936542 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  144 bits (363), Expect = 5e-35
 Identities = 82/182 (45%), Positives = 120/182 (65%), Gaps = 12/182 (6%)

Query: 28  LYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDY 86
           L++ E+FQG+RC L ++C ++ +   L +V S++VE+G W+AFE   F+G+QF+LEKGDY
Sbjct: 16  LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75

Query: 87  PRWDAW--SNSRDSDSLLSLRP-LNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
           PRW AW  S+S +S+ LLS RP L  +    ++ LFE   F G K ++V DD PSL + G
Sbjct: 76  PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMG 134

Query: 144 FQDR-VASVRAINGTWVGYEFPGYRGRQYVFER----GEYRHWNE--WDASQPQLQSVRR 196
           +  + V S++  +G WV Y++PGYRG QYV ER    GE+  + E    A   QLQS+RR
Sbjct: 135 WASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRR 194

Query: 197 IR 198
           ++
Sbjct: 195 VQ 196



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDS--LLEKVGSIQVESGPWLAFESRAFRGEQFVLE 82
           +V L+E +NFQG + +L  + PSL       + VGS++V SG W+A++   +RG Q+VLE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 83  K----GDYPRWDAWSNSRDSDSLLSLR 105
           +    G++  +        +  L S+R
Sbjct: 167 RDRHSGEFCTYGELGTQAHTGQLQSIR 193


>gi|16936540 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  144 bits (363), Expect = 5e-35
 Identities = 82/182 (45%), Positives = 120/182 (65%), Gaps = 12/182 (6%)

Query: 28  LYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDY 86
           L++ E+FQG+RC L ++C ++ +   L +V S++VE+G W+AFE   F+G+QF+LEKGDY
Sbjct: 16  LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75

Query: 87  PRWDAW--SNSRDSDSLLSLRP-LNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
           PRW AW  S+S +S+ LLS RP L  +    ++ LFE   F G K ++V DD PSL + G
Sbjct: 76  PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMG 134

Query: 144 FQDR-VASVRAINGTWVGYEFPGYRGRQYVFER----GEYRHWNE--WDASQPQLQSVRR 196
           +  + V S++  +G WV Y++PGYRG QYV ER    GE+  + E    A   QLQS+RR
Sbjct: 135 WASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRR 194

Query: 197 IR 198
           ++
Sbjct: 195 VQ 196



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDS--LLEKVGSIQVESGPWLAFESRAFRGEQFVLE 82
           +V L+E +NFQG + +L  + PSL       + VGS++V SG W+A++   +RG Q+VLE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 83  K----GDYPRWDAWSNSRDSDSLLSLR 105
           +    G++  +        +  L S+R
Sbjct: 167 RDRHSGEFCTYGELGTQAHTGQLQSIR 193


>gi|7019357 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score =  144 bits (363), Expect = 5e-35
 Identities = 82/182 (45%), Positives = 120/182 (65%), Gaps = 12/182 (6%)

Query: 28  LYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDY 86
           L++ E+FQG+RC L ++C ++ +   L +V S++VE+G W+AFE   F+G+QF+LEKGDY
Sbjct: 16  LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75

Query: 87  PRWDAW--SNSRDSDSLLSLRP-LNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
           PRW AW  S+S +S+ LLS RP L  +    ++ LFE   F G K ++V DD PSL + G
Sbjct: 76  PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMG 134

Query: 144 FQDR-VASVRAINGTWVGYEFPGYRGRQYVFER----GEYRHWNE--WDASQPQLQSVRR 196
           +  + V S++  +G WV Y++PGYRG QYV ER    GE+  + E    A   QLQS+RR
Sbjct: 135 WASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRR 194

Query: 197 IR 198
           ++
Sbjct: 195 VQ 196



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDS--LLEKVGSIQVESGPWLAFESRAFRGEQFVLE 82
           +V L+E +NFQG + +L  + PSL       + VGS++V SG W+A++   +RG Q+VLE
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 83  K----GDYPRWDAWSNSRDSDSLLSLR 105
           +    G++  +        +  L S+R
Sbjct: 167 RDRHSGEFCTYGELGTQAHTGQLQSIR 193


>gi|8922120 crystallin, gamma S [Homo sapiens]
          Length = 178

 Score =  120 bits (302), Expect = 6e-28
 Identities = 62/174 (35%), Positives = 96/174 (55%), Gaps = 5/174 (2%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+  YE +NFQG+R +   +C     + L +  SI+VE G W  +E   F G  ++L +G
Sbjct: 7   KITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSP-HHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
           +YP +  W     +D L S R +++ S   +K+ +FE   FSG+  E  +D  PS+    
Sbjct: 66  EYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTED-CPSIMEQF 122

Query: 144 FQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRI 197
               + S + + G W+ YE P YRGRQY+ ++ EYR   +W A+ P +QS RRI
Sbjct: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 1/77 (1%)

Query: 17  HGDLGGSYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFR 75
           H   GG YK+ ++E  +F G+  E + +CPS+ +   + ++ S +V  G W+ +E   +R
Sbjct: 87  HLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYR 146

Query: 76  GEQFVLEKGDYPRWDAW 92
           G Q++L+K +Y +   W
Sbjct: 147 GRQYLLDKKEYRKPIDW 163


>gi|10518338 crystallin, gamma C [Homo sapiens]
          Length = 174

 Score =  118 bits (295), Expect = 4e-27
 Identities = 61/175 (34%), Positives = 92/175 (52%), Gaps = 5/175 (2%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+  YE   FQG+  E + +CP+L      +  SI+VESG W+ +E   ++G+Q++L +G
Sbjct: 3   KITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
           +YP +  W    DS     L P  +    H+L L+E     G  ME+  +D PS+     
Sbjct: 62  EYPDYQQWMGLSDSIRSCCLIPQTVS---HRLRLYEREDHKGLMMEL-SEDCPSIQDRFH 117

Query: 145 QDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199
              + S+  + G WV YE P YRGRQY+    EYR   +W A   +  S+RR+ D
Sbjct: 118 LSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 23  SYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           S+++ LYE E+ +G   ELS +CPS+ D   L ++ S+ V  G W+ +E   +RG Q++L
Sbjct: 87  SHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLL 146

Query: 82  EKGDYPRWDAW 92
              +Y R   W
Sbjct: 147 RPQEYRRCQDW 157


>gi|148491074 crystallin, gamma B [Homo sapiens]
          Length = 175

 Score =  112 bits (281), Expect = 2e-25
 Identities = 59/180 (32%), Positives = 96/180 (53%), Gaps = 14/180 (7%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+  YE   FQG+  E + +CP+L      +  SI+VESG W+ +E   ++G Q+ L +G
Sbjct: 3   KITFYEDRAFQGRSYECTTDCPNL-QPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRRG 61

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
           +YP +  W    DS     L P +  S  +++ +++     G+  E+ DD +        
Sbjct: 62  EYPDYQQWMGLSDSIRSCCLIPPH--SGAYRMKIYDRDELRGQMSELTDDCI------SV 113

Query: 145 QDR-----VASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199
           QDR     + S+  + G+W+ YE P YRGRQY+   GEYR + +W A   ++ S+RR+ D
Sbjct: 114 QDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMD 173



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFV 80
           G+Y++ +Y+ +  +G+  EL+ +C S+ D   L ++ S+ V  G W+ +E   +RG Q++
Sbjct: 87  GAYRMKIYDRDELRGQMSELTDDCISVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYL 146

Query: 81  LEKGDYPRWDAW 92
           L  G+Y R+  W
Sbjct: 147 LRPGEYRRFLDW 158


>gi|148491057 crystallin, gamma A [Homo sapiens]
          Length = 174

 Score =  112 bits (280), Expect = 2e-25
 Identities = 63/180 (35%), Positives = 98/180 (54%), Gaps = 15/180 (8%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+  YE  +FQG+     ++CP+L      +  SI+V+SG W+ +E   ++G Q+ L +G
Sbjct: 3   KITFYEDRDFQGRCYNCISDCPNLR-VYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPH---HKLHLFENPAFSGRKMEIVDDD--VPSL 139
            YP +  W     SDS+ S R +    PH   HKL L+E   + G   E+ DD   VP L
Sbjct: 62  KYPDYQHWMGL--SDSVQSCRII----PHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115

Query: 140 WAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199
           +       + S+  + G WV YE P YRGRQY+   G+YR +++W  +  ++ S+RR+ D
Sbjct: 116 FR---LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174
           K+  +E+  F GR    + D  P+L    +  R  S+R  +G W+ YE P Y+G QY   
Sbjct: 3   KITFYEDRDFQGRCYNCISD-CPNLRV--YFSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59

Query: 175 RGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204
           RG+Y  +  W      +QS R I     HK
Sbjct: 60  RGKYPDYQHWMGLSDSVQSCRIIPHTSSHK 89



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 1/74 (1%)

Query: 23  SYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           S+K+ LYE ++++G   EL+ +C  + +   L ++ S+ V  G W+ +E   +RG Q++L
Sbjct: 87  SHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL 146

Query: 82  EKGDYPRWDAWSNS 95
             GDY R+  W  +
Sbjct: 147 RPGDYRRYHDWGGA 160


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score =  106 bits (264), Expect = 2e-23
 Identities = 60/180 (33%), Positives = 93/180 (51%), Gaps = 15/180 (8%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+ LYE   FQG+  E S++ P+L    L +  S +V+SG W+ +E   + G Q+ L +G
Sbjct: 3   KITLYEDRGFQGRHYECSSDHPNL-QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61

Query: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
           DY     W    DS     L P    S  H++ L+E   + G+ +E  +D          
Sbjct: 62  DYADHQQWMGLSDSVRSCRLIP---HSGSHRIRLYEREDYRGQMIEFTED------CSCL 112

Query: 145 QDR-----VASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199
           QDR     + S+  + G+WV YE   YRGRQY+   G+YR + +W A+  ++ S+RR+ D
Sbjct: 113 QDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172



 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFV 80
           GS+++ LYE E+++G+  E + +C  L D     ++ S+ V  G W+ +E   +RG Q++
Sbjct: 86  GSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYL 145

Query: 81  LEKGDYPRWDAW 92
           L  GDY R+  W
Sbjct: 146 LMPGDYRRYQDW 157



 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174
           K+ L+E+  F GR  E   D  P+L    +  R  S R  +G W+ YE P Y G QY   
Sbjct: 3   KITLYEDRGFQGRHYECSSDH-PNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLR 59

Query: 175 RGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204
           RG+Y    +W      ++S R I     H+
Sbjct: 60  RGDYADHQQWMGLSDSVRSCRLIPHSGSHR 89


>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
           sapiens]
          Length = 1022

 Score =  104 bits (260), Expect = 5e-23
 Identities = 58/179 (32%), Positives = 99/179 (55%), Gaps = 7/179 (3%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSL-----LEKVGSIQVESGPWLAFESRAFRGEQF 79
           KVI+YE  +F G+  E S    S+ + L       ++GSI+V  G W+A+E   F+G+QF
Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591

Query: 80  VLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSL 139
           +LE+GD+   D+ +    S  +LS R L  +     + LFE+   SG+ ++I + ++  L
Sbjct: 592 LLEEGDFE--DSNACGALSSPILSFRYLQANFIESSVTLFESDLESGKFIDITNQEISDL 649

Query: 140 WAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIR 198
              GF  +  S+   +G WV Y+   + G QY+ E+G+Y+ + +W  S   + S+R I+
Sbjct: 650 EEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQ 708



 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 48/157 (30%), Positives = 83/157 (52%), Gaps = 5/157 (3%)

Query: 46  PSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLR 105
           P+L +  + K  S  V+SG WLA+    F+G+  VLE+ D+  ++  +    S   L + 
Sbjct: 463 PNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEE-DHGLFEISTAEMKSLHPLQMG 521

Query: 106 PLNIDSPHH-KLHLFENPAFSGRKMEIVD--DDVPS-LWAHGFQDRVASVRAINGTWVGY 161
            L ++ P + K+ ++E P F G+  E  +  D VP+ L  +G   R+ S+R I G WV Y
Sbjct: 522 GLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAY 581

Query: 162 EFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIR 198
           E   ++G+Q++ E G++   N   A    + S R ++
Sbjct: 582 EKEHFKGQQFLLEEGDFEDSNACGALSSPILSFRYLQ 618



 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 52/183 (28%), Positives = 86/183 (46%), Gaps = 22/183 (12%)

Query: 26  VILYELENFQGKRCELSAECPSLTDSLLEKVG------SIQVESGPWLAFESRAFRGEQF 79
           V L+E +   GK  +++ +   ++D  LE++G      SI V+SG W+A++ + F GEQ+
Sbjct: 626 VTLFESDLESGKFIDITNQ--EISD--LEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQY 681

Query: 80  VLEKGDYPRWDAWSNSRD---SDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDD-- 134
           +LEKG Y  +  W  S +   S   + L PL I+ P H L  F  P F G  ++  ++  
Sbjct: 682 ILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEETS 741

Query: 135 DVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSV 194
           D+ SL          S + + G W+ Y          V E G Y           +++S+
Sbjct: 742 DLTSLMP-------CSFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPASKVKSL 794

Query: 195 RRI 197
           + I
Sbjct: 795 KPI 797



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 6/148 (4%)

Query: 34  FQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS 93
           FQG+  + + E   LT  +     S +V  G WL +          VLE+G Y   D  S
Sbjct: 729 FQGECIDFTEETSDLTSLM---PCSFKVLRGCWLLYYQEDMFVNHCVLEEGLYA--DLTS 783

Query: 94  NSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRA 153
               +  + SL+P++       + LF      GR++ + ++ V S+          SV  
Sbjct: 784 CGCPASKVKSLKPIDYVFEEPSISLFALEHCEGRELHL-EEAVNSVLNKDLHFYTQSVWV 842

Query: 154 INGTWVGYEFPGYRGRQYVFERGEYRHW 181
            +G W+ YE   + GRQ +    E  +W
Sbjct: 843 KSGLWIAYEGSNFLGRQILLRPNEIPNW 870



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 4/83 (4%)

Query: 26  VILYELENFQGKRCELSAECPSLTDSLLE-KVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           + L+ LE+ +G+   L     S+ +  L     S+ V+SG W+A+E   F G Q +L   
Sbjct: 806 ISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRPN 865

Query: 85  DYPRWDAWSNSRDSDSLLSLRPL 107
           + P W A+S  +   ++ SLRP+
Sbjct: 866 EIPNWTAFSRWK---TIGSLRPM 885



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 12/157 (7%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           K+++Y+L     K+ E+    P  T         I+V  G W+ +E   FRG++ VLE+G
Sbjct: 348 KMVIYDLHESTYKQ-EVYCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFRGQKCVLEEG 406

Query: 85  DYPRWDAW--SNSRDSDS---LLSLRPLNIDSPHHKLHLF--ENPAFSGRKMEIVDDDVP 137
           +      W   N R       L SL+ +  D    ++ LF   +PA        +   VP
Sbjct: 407 EKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSIPEIELFPQSDPACC---PVYIQRAVP 463

Query: 138 SLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174
           +L        V S    +G W+ Y    ++G+  V E
Sbjct: 464 NLEELNISKSV-SFTVKSGVWLAYPDINFKGQATVLE 499



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 8/70 (11%)

Query: 135 DVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGE---YRHWNEWDASQPQ- 190
           ++P   +  F + V  ++ + G W+ YE P +RG++ V E GE    R W   +   PQ 
Sbjct: 366 NIPDATSWSFPNGVL-IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQR 424

Query: 191 ---LQSVRRI 197
              L S++R+
Sbjct: 425 NFILGSLKRV 434


>gi|89886227 absent in melanoma 1-like [Homo sapiens]
          Length = 616

 Score =  103 bits (258), Expect = 8e-23
 Identities = 60/182 (32%), Positives = 93/182 (51%), Gaps = 9/182 (4%)

Query: 22  GSYKVILYELENFQGKRCELSAECPSLT---DSL---LEKVGSIQVESGPWLAFESRAFR 75
           G  + ++YE   FQG+  E+S +  +L    DS    L  VGS++V  G W+ +E   FR
Sbjct: 121 GEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFR 180

Query: 76  GEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDD 135
           G Q++LE+G+YP W  W      + L SLR +  D     + LFE   F G  +E V   
Sbjct: 181 GHQYLLEEGEYPDWSHWGGY--DELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVE-VSKA 237

Query: 136 VPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVR 195
           +P +          ++  ++G WV Y+  G+ G QYV E+G YR+  +W A    L S++
Sbjct: 238 LPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQ 297

Query: 196 RI 197
            +
Sbjct: 298 PV 299



 Score = 94.0 bits (232), Expect = 8e-20
 Identities = 60/187 (32%), Positives = 89/187 (47%), Gaps = 17/187 (9%)

Query: 25  KVILYELENFQGKRCELSAECPSLTDSLLEK---VGSIQVESGPWLAFESRAFRGEQFVL 81
           ++ L+  E  +G++ +L+    +     LEK   V S  V +G WL +    F    ++L
Sbjct: 29  EISLFSEEGLKGEQVKLTEALKNSQG--LEKPLQVASATVSAGLWLLYPKPLFEDTPYIL 86

Query: 82  EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSP------HHKLHLFENPAFSGRKMEIVDDD 135
           E G+YP  +AW  S    S+ SL+P+ +  P        +  ++E P F GR  E+  D 
Sbjct: 87  EPGEYPTSEAWGTS--DPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDI 144

Query: 136 VPSLWAHGFQD----RVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQL 191
                    Q      V S+R + G WVGYE  G+RG QY+ E GEY  W+ W      L
Sbjct: 145 YNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELL 204

Query: 192 QSVRRIR 198
            S+R IR
Sbjct: 205 TSLRVIR 211



 Score = 71.2 bits (173), Expect = 6e-13
 Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 4/170 (2%)

Query: 19  DLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQ 78
           DL    K+ L+   +F G       +  +L  S   +  S +V  G W+ F+   F G+Q
Sbjct: 306 DLHFVSKIQLFSRPDFLGDHFSFEDDQAALPASFRPQ--SCRVHGGSWILFDETNFEGDQ 363

Query: 79  FVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPS 138
            +L +G++P   A      S  L SL+ +++      + L+    F G+++E+   +V S
Sbjct: 364 HILSEGEFPTLTAMG-CLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIEL-SREVRS 421

Query: 139 LWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQ 188
           L A GF + V SVR   G WV  E   +RGRQ++    E  +W  +  +Q
Sbjct: 422 LQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQ 471



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 1/81 (1%)

Query: 26  VILYELENFQGKRCELSAECPSL-TDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
           + LY LE F+GK  ELS E  SL  +     V S++++ G W+  E   FRG Q+++   
Sbjct: 400 IFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSC 459

Query: 85  DYPRWDAWSNSRDSDSLLSLR 105
           +   W  +S ++   SL  ++
Sbjct: 460 EITNWLTYSGTQRVGSLYPIK 480


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 58/187 (31%), Positives = 91/187 (48%), Gaps = 16/187 (8%)

Query: 25   KVILYELENFQGKRCELSAECPSLT------------DSL-LEKVGSIQVESGPWLAFES 71
            KV++YE   F+GK  EL     S              D L    VGS++V  G W+A+E 
Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEK 1278

Query: 72   RAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEI 131
              F G Q++LE+G+Y  W AW     +  L SLRP+  D  +  + ++    F  +   I
Sbjct: 1279 PGFTGHQYLLEEGEYRDWKAWGGY--NGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSI 1336

Query: 132  -VDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQ 190
             V   V +L   G+  +  S+  ++G WV YE P + G QY+ ++G Y  + +W     +
Sbjct: 1337 DVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNCK 1396

Query: 191  LQSVRRI 197
            + SV+ I
Sbjct: 1397 ISSVQPI 1403



 Score = 90.9 bits (224), Expect = 7e-19
 Identities = 51/163 (31%), Positives = 80/163 (49%), Gaps = 19/163 (11%)

Query: 52   LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS 111
            +++K  S++V  G WL +E   F+G  F+LE G+YP    W    ++  + S+RPL +  
Sbjct: 1152 VMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDT--EAAYIGSMRPLKMGG 1209

Query: 112  ------PHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDR-----------VASVRAI 154
                     K+ ++E P F G+ +E+       +   G  +            V S++ +
Sbjct: 1210 RKVEFPTDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVL 1269

Query: 155  NGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRI 197
             G WV YE PG+ G QY+ E GEYR W  W     +LQS+R I
Sbjct: 1270 RGIWVAYEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPI 1312



 Score = 88.2 bits (217), Expect = 5e-18
 Identities = 54/171 (31%), Positives = 88/171 (51%), Gaps = 5/171 (2%)

Query: 25   KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
            ++ L+    FQG           + DS   K  S +V  G W+ ++   F G Q+VLE+G
Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFSTK--SCRVSGGSWVVYDGENFTGNQYVLEEG 1473

Query: 85   DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144
             YP   A      + +  SLR ++++     + LFE   F G+K+E+  + V +L + GF
Sbjct: 1474 HYPCLSAMGCPPGA-TFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETV-NLRSLGF 1531

Query: 145  QDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVR 195
              ++ SV+ I G WV YE+  YRGRQ++    E  +W E+   + Q+ S+R
Sbjct: 1532 NTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGCR-QIGSLR 1581



 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 12/185 (6%)

Query: 25   KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
            KV++Y   +   K  E+ ++    +   L  V  I+V  G W+ +E   F G    LE+G
Sbjct: 1023 KVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEEG 1082

Query: 85   DYPRWDAWSNS---RDSDSLLSLRPLNIDSPHH--------KLHLFENPAFSGRKMEIVD 133
            +      W         +   S +P+ I S  H         + LF  P   G  +    
Sbjct: 1083 ELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGI-LSSYF 1141

Query: 134  DDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQS 193
            DD   +   G   +  S++   GTW+ YE PG++G  ++ E GEY   + WD     + S
Sbjct: 1142 DDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGS 1201

Query: 194  VRRIR 198
            +R ++
Sbjct: 1202 MRPLK 1206


>gi|21389517 gammaN-crystallin [Homo sapiens]
          Length = 182

 Score = 90.9 bits (224), Expect = 7e-19
 Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 4/123 (3%)

Query: 23  SYKVILYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
           S K+ LYE ++F G++ E+  +C +  D   + +V SI VESG W+ F    FRG+QF+L
Sbjct: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64

Query: 82  EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141
           E GDYP +  W++   SD + S RP+ +   H +L +FE   F+G+ +E ++D  P L +
Sbjct: 65  EHGDYPDFFRWNS--HSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDS-PFLQS 121

Query: 142 HGF 144
            G+
Sbjct: 122 RGW 124



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 1/83 (1%)

Query: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174
           K+ L+E   F+G+K+E+  D   +    GF +RV S+   +G WV +  P +RG+Q++ E
Sbjct: 7   KITLYEGKHFTGQKLEVFGD-CDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65

Query: 175 RGEYRHWNEWDASQPQLQSVRRI 197
            G+Y  +  W++    + S R +
Sbjct: 66  HGDYPDFFRWNSHSDHMGSCRPV 88


>gi|4503299 basic helix-loop-helix family, member e40 [Homo
          sapiens]
          Length = 412

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 12 AAGKSHGDLGGSYKVILYELENFQG--KRCELSAECPSLTDSLLEK 55
          A G  HGDL G Y   +Y++   +   KR E S E   L   L+EK
Sbjct: 17 APGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEK 62


>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
           sapiens]
          Length = 335

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 82  EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENP 122
           ++G++  W A   S  +D  L + P N D+  HK +LFE P
Sbjct: 271 KQGNFNAWVA--GSYGNDQWLQIFPGNWDNHSHKKNLFETP 309


>gi|239750232 PREDICTED: hypothetical protein XP_002347325 [Homo
           sapiens]
          Length = 139

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 8/48 (16%)

Query: 81  LEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRK 128
           L+ G+ P+W  W      D++L          H  L +  +P  SG K
Sbjct: 7   LQHGESPKWPVWKRKESEDTMLRF--------HASLEVSVSPQSSGNK 46


>gi|118918417 testis specific protein, Y-linked 2 [Homo sapiens]
          Length = 308

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 24/97 (24%)

Query: 46  PSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDA-----------WSN 94
           P   +S LE++ ++QVE  P  A   +AF  ++  +E+   P  D            W+N
Sbjct: 102 PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWAN 161

Query: 95  -------------SRDSDSLLSLRPLNIDSPHHKLHL 118
                          D D L  +  L ++   H++HL
Sbjct: 162 VIANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHL 198


>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
          Length = 1806

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 14/121 (11%)

Query: 23   SYKVILYELENFQ-GKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
            ++  + Y++ N Q  K   LS       +SLLE    I   S P     +    G +  L
Sbjct: 1026 TFFAVTYQIPNTQKAKGVVLSG-----AESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080

Query: 82   EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141
            E      W       ++  L +L+P +  S    L  +    F+GR +     DV +LW+
Sbjct: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPS---SLGAWSLDPFNGRII-----DVDALWS 1132

Query: 142  H 142
            H
Sbjct: 1133 H 1133


>gi|239758109 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 139

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 8/48 (16%)

Query: 81  LEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRK 128
           L+ G+ P+W  W      D++L          H  L +  +P  SG K
Sbjct: 7   LKHGESPKWPVWKRKESEDTMLRF--------HASLEVSVSPQSSGNK 46


>gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo
            sapiens]
          Length = 1595

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 14/121 (11%)

Query: 23   SYKVILYELENFQ-GKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81
            ++  + Y++ N Q  K   LS       +SLLE    I   S P     +    G +  L
Sbjct: 1026 TFFAVTYQIPNTQKAKGVVLSG-----AESLLEHSRKITPPSSPHSLTSTLVSLGHEEAL 1080

Query: 82   EKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141
            E      W       ++  L +L+P +  S    L  +    F+GR +     DV +LW+
Sbjct: 1081 EMAGSKNWMKGREHENASILKTLKPTDRPS---SLGAWSLDPFNGRII-----DVDALWS 1132

Query: 142  H 142
            H
Sbjct: 1133 H 1133


>gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]
          Length = 614

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 14/91 (15%)

Query: 42  SAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSL 101
           S +  S  D L  + G   +   PW +  ++ F           Y  W   S+ +  D L
Sbjct: 470 SQKSRSEQDLLNNRTGCQMLLDNPWKSDSNQVF----------SYKVWTVSSSDKLLDRL 519

Query: 102 LSLRP--LNIDSPHHKLHLFENPAFSGRKME 130
           LS+RP    +  P H  HL  NP+ SG+  +
Sbjct: 520 LSVRPGHQEVSVPPHLRHL-HNPS-SGQNFQ 548


>gi|90186264 ankyrin repeat domain 55 isoform 2 [Homo sapiens]
          Length = 326

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 14/91 (15%)

Query: 42  SAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSL 101
           S +  S  D L  + G   +   PW +  ++ F           Y  W   S+ +  D L
Sbjct: 182 SQKSRSEQDLLNNRTGCQMLLDNPWKSDSNQVF----------SYKVWTVSSSDKLLDRL 231

Query: 102 LSLRP--LNIDSPHHKLHLFENPAFSGRKME 130
           LS+RP    +  P H  HL  NP+ SG+  +
Sbjct: 232 LSVRPGHQEVSVPPHLRHL-HNPS-SGQNFQ 260


>gi|239747006 PREDICTED: similar to testis specific protein,
           Y-linked 3 [Homo sapiens]
          Length = 314

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 24/97 (24%)

Query: 46  PSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDA-----------WSN 94
           P   +S LE++ ++QVE  P  A   +AF  ++  +E+   P+ D            W+N
Sbjct: 108 PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPQLDRRGAVIQSVPGFWAN 167

Query: 95  -------------SRDSDSLLSLRPLNIDSPHHKLHL 118
                          D D L  +  L ++   H +HL
Sbjct: 168 VIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHL 204


>gi|239746996 PREDICTED: similar to Testis-specific Y-encoded
           protein 1 [Homo sapiens]
          Length = 308

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 31/150 (20%), Positives = 54/150 (36%), Gaps = 24/150 (16%)

Query: 46  PSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDA-----------WSN 94
           P   +S LE++ ++QVE  P  A   +AF  ++  +E+   P  D            W+N
Sbjct: 102 PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWAN 161

Query: 95  -------------SRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWA 141
                          D D L  +  L ++   H +HL +   F        +  +   + 
Sbjct: 162 VIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYL 221

Query: 142 HGFQDRVASVRAINGTWVGYEFPGYRGRQY 171
               +  AS       ++ YE   YR R +
Sbjct: 222 VNITEYRASHSTPIEWYLDYEVEAYRRRHH 251


>gi|118026929 testis specific protein, Y-linked 3 [Homo sapiens]
          Length = 308

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 23/97 (23%), Positives = 39/97 (40%), Gaps = 24/97 (24%)

Query: 46  PSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDA-----------WSN 94
           P   +S LE++ ++QVE  P  A   +AF  ++  +E+   P+ D            W+N
Sbjct: 102 PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPQLDRRGAVIQSVPGFWAN 161

Query: 95  -------------SRDSDSLLSLRPLNIDSPHHKLHL 118
                          D D L  +  L ++   H +HL
Sbjct: 162 VIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHL 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,967,480
Number of Sequences: 37866
Number of extensions: 396968
Number of successful extensions: 877
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 745
Number of HSP's gapped (non-prelim): 54
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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