Guide to the Human Genome
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Search of human proteins with 108773799

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108773799 ganglioside-induced differentiation-associated
protein 1 isoform b [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|108773799 ganglioside-induced differentiation-associated prot...   582   e-166
gi|108773797 ganglioside-induced differentiation-associated prot...   582   e-166
gi|30581160 ganglioside-induced differentiation-associated prote...   310   1e-84
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       37   0.020
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        37   0.020
gi|54633317 thioredoxin domain containing 11 [Homo sapiens]            37   0.027
gi|50083279 centrosome protein 4 [Homo sapiens]                        36   0.035
gi|209863034 periostin, osteoblast specific factor isoform 4 [Ho...    36   0.045
gi|216548091 leucine zipper protein 1 [Homo sapiens]                   35   0.059
gi|216548085 leucine zipper protein 1 [Homo sapiens]                   35   0.059
gi|82617632 chloride intracellular channel 5 isoform b [Homo sap...    35   0.077
gi|166197662 chloride intracellular channel 5 isoform a [Homo sa...    35   0.077
gi|209862911 periostin, osteoblast specific factor isoform 2 [Ho...    35   0.10 
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    34   0.13 
gi|134152708 arginine and glutamate rich 1 [Homo sapiens]              34   0.17 
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     33   0.29 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    33   0.29 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    33   0.29 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    33   0.29 
gi|119395750 keratin 1 [Homo sapiens]                                  32   0.50 
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap...    32   0.65 
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap...    32   0.65 
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    32   0.85 
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub...    32   0.85 
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     32   0.85 
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    32   0.85 
gi|154937324 hypothetical protein LOC440295 [Homo sapiens]             32   0.85 
gi|66346733 chloride intracellular channel 2 [Homo sapiens]            31   1.1  
gi|131889097 cancer susceptibility candidate 1 isoform b [Homo s...    31   1.1  
gi|131889447 cancer susceptibility candidate 1 isoform c [Homo s...    31   1.1  

>gi|108773799 ganglioside-induced differentiation-associated protein
           1 isoform b [Homo sapiens]
          Length = 290

 Score =  582 bits (1501), Expect = e-166
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL 60
           MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL
Sbjct: 1   MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL 60

Query: 61  DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK 120
           DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK
Sbjct: 61  DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK 120

Query: 121 QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD 180
           QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD
Sbjct: 121 QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD 180

Query: 181 VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA 240
           VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA
Sbjct: 181 VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA 240

Query: 241 FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF 290
           FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF
Sbjct: 241 FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF 290


>gi|108773797 ganglioside-induced differentiation-associated protein
           1 isoform a [Homo sapiens]
          Length = 358

 Score =  582 bits (1501), Expect = e-166
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL 60
           MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL
Sbjct: 69  MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL 128

Query: 61  DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK 120
           DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK
Sbjct: 129 DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAK 188

Query: 121 QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD 180
           QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD
Sbjct: 189 QKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLAD 248

Query: 181 VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA 240
           VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA
Sbjct: 249 VSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTA 308

Query: 241 FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF 290
           FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF
Sbjct: 309 FRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF 358


>gi|30581160 ganglioside-induced differentiation-associated protein
           1-like 1 [Homo sapiens]
          Length = 367

 Score =  310 bits (793), Expect = 1e-84
 Identities = 151/276 (54%), Positives = 199/276 (72%), Gaps = 1/276 (0%)

Query: 1   MRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELL 60
           MRLN   EVPV+IH +NII +  QIIDY+E+TF  E    LMP+  S+ + RV  YRELL
Sbjct: 90  MRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEVGSLQHARVLQYRELL 149

Query: 61  DSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLA-EENPDLQEAYIA 119
           D+LPMDAYTHGCILHPELT DSMIP YAT  IR  + N  ++L KL  EE P L E Y++
Sbjct: 150 DALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLS 209

Query: 120 KQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLA 179
           KQK+L +K+L+HD+V YLKKIL EL  VLDQ+E EL++R  E   +  + WLCG +FTLA
Sbjct: 210 KQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQKCELWLCGCAFTLA 269

Query: 180 DVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPT 239
           DV L  TLHRLKFLG +++ W +G RPNL++++ERV +R  F KVLG ++  L+SAV+P 
Sbjct: 270 DVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPN 329

Query: 240 AFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKR 275
           AFR+ K++ P   G + ++G L G+GYFA+   +K+
Sbjct: 330 AFRLVKRKPPSFFGASFLMGSLGGMGYFAYWYLKKK 365


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 11/80 (13%)

Query: 91   RIRSQIGNTESELKKLAEENPDLQ---------EAYIAKQKRLKSKLLDHDNVKYLKKIL 141
            +++S   ++E EL++L  EN D++         E  + K +  +S  +    V+ LK +L
Sbjct: 1177 QMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTE--VRELKDLL 1234

Query: 142  DELEKVLDQVETELQRRNEE 161
             EL+K LD   +E  R+NEE
Sbjct: 1235 TELQKKLDDSYSEAVRQNEE 1254


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 11/80 (13%)

Query: 91   RIRSQIGNTESELKKLAEENPDLQ---------EAYIAKQKRLKSKLLDHDNVKYLKKIL 141
            +++S   ++E EL++L  EN D++         E  + K +  +S  +    V+ LK +L
Sbjct: 1177 QMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTE--VRELKDLL 1234

Query: 142  DELEKVLDQVETELQRRNEE 161
             EL+K LD   +E  R+NEE
Sbjct: 1235 TELQKKLDDSYSEAVRQNEE 1254


>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
          Length = 958

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 93  RSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVE 152
           R  I + E E++KL  E   LQ A +  + +L S   D   ++  ++ L+E   +L    
Sbjct: 797 RGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHS 856

Query: 153 TELQRRNEETPEEGQQPWLCGESFTLADVS 182
            +LQ   E+   E Q+  L  +   LAD S
Sbjct: 857 EQLQALYEQKTRELQE--LARKLQELADAS 884


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 36.2 bits (82), Expect = 0.035
 Identities = 48/239 (20%), Positives = 100/239 (41%), Gaps = 31/239 (12%)

Query: 16  ENIICEATQIIDYLEQTF--LDERTPRLMPDKESMYYPRV----QHYRELLDSLPMDAYT 69
           E +I      +D+L+Q    L++R   LM  KE++    V    ++ +   +   +D   
Sbjct: 267 EKLIAHLNIQVDFLQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLA 326

Query: 70  HGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLL 129
                H E  +++            ++G  + E+K+   E  DL+E     Q  L     
Sbjct: 327 QQLERHKEEVLETA---------DKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQK 377

Query: 130 DHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHR 189
           + + +     +  +LE V+ Q+E E QR +++            ESF + +  L + + R
Sbjct: 378 EKERLSDELLVKSDLETVVHQLEQEKQRLSKKV-----------ESFAVTERQLTLEVER 426

Query: 190 LKF-LGFARRNWGNGKRPNLETYYERV-LKRKTFNKVLGHVNNILISAVLPTAFRVAKK 246
           ++   G  RR+    +   L+T+ + +  +R  + K L  + +I+      T++   +K
Sbjct: 427 MRLEHGIKRRDRSPSR---LDTFLKGIEEERDYYKKELERLQHIIQRRSCSTSYSAREK 482


>gi|209863034 periostin, osteoblast specific factor isoform 4 [Homo
           sapiens]
          Length = 751

 Score = 35.8 bits (81), Expect = 0.045
 Identities = 26/100 (26%), Positives = 52/100 (52%), Gaps = 10/100 (10%)

Query: 24  QIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSM 83
           ++I Y++  F+   T + +P   ++Y P ++ Y +++D +P++      I   E   + +
Sbjct: 646 KLIKYIQIKFVRGSTFKEIP--VTVYKPIIKKYTKIIDGVPVE------ITEKETREERI 697

Query: 84  I--PAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQ 121
           I  P    TRI +  G TE  LKKL +E+  +++    K+
Sbjct: 698 ITGPEIKYTRISTGGGETEETLKKLLQEDTPVRKLQANKK 737


>gi|216548091 leucine zipper protein 1 [Homo sapiens]
          Length = 1076

 Score = 35.4 bits (80), Expect = 0.059
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 10/117 (8%)

Query: 91  RIRSQIGNTES---ELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKV 147
           ++++QI + ES   ELKK+  +N DLQ+ Y+++Q + K      + +K   K   ELE  
Sbjct: 297 KLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELEN- 355

Query: 148 LDQVETE-----LQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRN 199
             +VE E      + R+E T   G          T  ++S      RL+   FA  N
Sbjct: 356 -GEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNN 411


>gi|216548085 leucine zipper protein 1 [Homo sapiens]
          Length = 1076

 Score = 35.4 bits (80), Expect = 0.059
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 10/117 (8%)

Query: 91  RIRSQIGNTES---ELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKV 147
           ++++QI + ES   ELKK+  +N DLQ+ Y+++Q + K      + +K   K   ELE  
Sbjct: 297 KLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELEN- 355

Query: 148 LDQVETE-----LQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRN 199
             +VE E      + R+E T   G          T  ++S      RL+   FA  N
Sbjct: 356 -GEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNN 411


>gi|82617632 chloride intracellular channel 5 isoform b [Homo
           sapiens]
          Length = 251

 Score = 35.0 bits (79), Expect = 0.077
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 116 AYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGES 175
           AYI   K+  +  L+    K LKK+ D L   L +   E+        +  ++ +L G+ 
Sbjct: 124 AYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPE---EIDANTCGEDKGSRRKFLDGDE 180

Query: 176 FTLADVSLAVTLHRLKFLGFARRNW 200
            TLAD +L   LH +K +    RN+
Sbjct: 181 LTLADCNLLPKLHVVKIVAKKYRNY 205


>gi|166197662 chloride intracellular channel 5 isoform a [Homo
           sapiens]
          Length = 410

 Score = 35.0 bits (79), Expect = 0.077
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 116 AYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGES 175
           AYI   K+  +  L+    K LKK+ D L   L +   E+        +  ++ +L G+ 
Sbjct: 283 AYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPE---EIDANTCGEDKGSRRKFLDGDE 339

Query: 176 FTLADVSLAVTLHRLKFLGFARRNW 200
            TLAD +L   LH +K +    RN+
Sbjct: 340 LTLADCNLLPKLHVVKIVAKKYRNY 364


>gi|209862911 periostin, osteoblast specific factor isoform 2 [Homo
           sapiens]
          Length = 779

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 10/88 (11%)

Query: 24  QIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSM 83
           ++I Y++  F+   T + +P   ++Y P ++ Y +++D +P++      I   E   + +
Sbjct: 646 KLIKYIQIKFVRGSTFKEIP--VTVYKPIIKKYTKIIDGVPVE------ITEKETREERI 697

Query: 84  I--PAYATTRIRSQIGNTESELKKLAEE 109
           I  P    TRI +  G TE  LKKL +E
Sbjct: 698 ITGPEIKYTRISTGGGETEETLKKLLQE 725


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 15/126 (11%)

Query: 92  IRSQIGNTESELKKLAEENPDL---------QEAYIAKQKRL---KSKLLDHDNVKYLKK 139
           +R Q    + + +K+ E+  ++         QE  + +Q+RL   K KL +H+ ++  +K
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788

Query: 140 ILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRN 199
           I ++ EK+ DQ E   + R +E    GQ+  + G+   +      +     K  G   + 
Sbjct: 789 IWEQEEKMRDQEE---KMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM 845

Query: 200 WGNGKR 205
           WG  ++
Sbjct: 846 WGQEEK 851



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 13/73 (17%)

Query: 99  TESELKKLAEENPDLQEAY-IAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVET---- 153
           T  ELKK   +N +LQE   +A+ ++ + +L    NVK LK+ L+  + +L QV+T    
Sbjct: 219 TNEELKK---KNAELQEKLPLAESEKSEIQL----NVKELKRKLERAKFLLPQVQTNTLQ 271

Query: 154 -ELQRRNEETPEE 165
            E+ R+ EE  E+
Sbjct: 272 EEMWRQEEELREQ 284



 Score = 29.3 bits (64), Expect = 4.2
 Identities = 18/66 (27%), Positives = 38/66 (57%), Gaps = 8/66 (12%)

Query: 108 EENPDLQEAYIAKQKRL---KSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPE 164
           EE    QE  + +Q+RL   K KL +H+ ++  +K+ ++ EK+ +Q     ++  ++T E
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ-----EKMEKKTQE 698

Query: 165 EGQQPW 170
           + ++ W
Sbjct: 699 QEKKTW 704


>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
          Length = 273

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 17/67 (25%), Positives = 38/67 (56%), Gaps = 5/67 (7%)

Query: 100 ESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYL-----KKILDELEKVLDQVETE 154
           E + ++  E+  + +     +Q+ ++ KL++ +  + +     K++ +ELEK  D++E E
Sbjct: 97  EKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIERE 156

Query: 155 LQRRNEE 161
           + RR EE
Sbjct: 157 VLRRVEE 163


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 12/105 (11%)

Query: 88   ATTRIRSQIGNTESELKKLAEENPDL--QEAYIAKQKRLKSKLL---------DHDNVKY 136
            A  +++ +   TE++LKKL EE   L  Q   +AK+K+L    +         + +  K 
Sbjct: 958  ARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017

Query: 137  LKKILDELEKVLDQVETELQRRNEETPE-EGQQPWLCGESFTLAD 180
            L K+ ++ E ++  +E  L+R  ++  E E  +  L G+S  L+D
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062



 Score = 28.5 bits (62), Expect = 7.2
 Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 81   DSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDH--DNVKYLK 138
            D++    A   +RS+     + LKK  EE     EA I + ++  S+ ++   + ++  K
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209

Query: 139  KILDELEKVLDQVETE 154
            ++   LEK    +E E
Sbjct: 1210 RVKANLEKAKQTLENE 1225


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 99   TESELKKLAEENPDLQEAYIAKQKRLKSKLL----DHDNVKYLKKILDELEKV---LDQV 151
            +E E+KK  +EN  L++     QK L+ K +     H+  + L +  DEL K    L Q 
Sbjct: 1006 SEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQK 1065

Query: 152  ETELQRRNEETPEE 165
             TE++   E+  EE
Sbjct: 1066 YTEVKNVKEKLVEE 1079


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 99   TESELKKLAEENPDLQEAYIAKQKRLKSKLL----DHDNVKYLKKILDELEKV---LDQV 151
            +E E+KK  +EN  L++     QK L+ K +     H+  + L +  DEL K    L Q 
Sbjct: 1019 SEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQK 1078

Query: 152  ETELQRRNEETPEE 165
             TE++   E+  EE
Sbjct: 1079 YTEVKNVKEKLVEE 1092


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 11/84 (13%)

Query: 90   TRIRSQIGNTESELKKLAEENP-------DLQEAYIAKQKRLKSKLLDHDNVKYLKKI-- 140
            T++ S+I     E  + A++ P       +LQE  + K+K+ + K L  D ++Y +KI  
Sbjct: 1980 TKVESEIRKEYLEKIQGAQKEPGNKSHAKELQE--LLKEKQQEVKQLQKDCIRYQEKISA 2037

Query: 141  LDELEKVLDQVETELQRRNEETPE 164
            L+   K L+ V+TE Q+  E T E
Sbjct: 2038 LERTVKALEFVQTESQKDLEITKE 2061


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 32.3 bits (72), Expect = 0.50
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 8/119 (6%)

Query: 91  RIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNV-----KYLKKILDELE 145
           R+RS+I N + ++  L +   D ++      K  K+KL D ++      + L ++L + +
Sbjct: 407 RLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQ 466

Query: 146 KVLD-QVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNG 203
           ++++ ++  +L+     T  EG++  + GE     +VS++V+       G   R  G G
Sbjct: 467 ELMNTKLALDLEIATYRTLLEGEESRMSGE--CAPNVSVSVSTSHTTISGGGSRGGGGG 523


>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 32.0 bits (71), Expect = 0.65
 Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 5/64 (7%)

Query: 92  IRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLL----DHDNVK-YLKKILDELEK 146
           +  QI + ESELKKL  E    +   I K+++L +        H++VK Y + ++++  K
Sbjct: 320 LEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNK 379

Query: 147 VLDQ 150
           V ++
Sbjct: 380 VQEK 383


>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 32.0 bits (71), Expect = 0.65
 Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 5/64 (7%)

Query: 92  IRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLL----DHDNVK-YLKKILDELEK 146
           +  QI + ESELKKL  E    +   I K+++L +        H++VK Y + ++++  K
Sbjct: 320 LEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNK 379

Query: 147 VLDQ 150
           V ++
Sbjct: 380 VQEK 383


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 31.6 bits (70), Expect = 0.85
 Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 4/72 (5%)

Query: 100 ESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVK-YLKKILDELEKVLDQVET---EL 155
           + ++ +L +E   LQE  + + + LKS L D++  K  L+K L+E++   + +++   E+
Sbjct: 805 DEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEM 864

Query: 156 QRRNEETPEEGQ 167
           +  NE+T  E Q
Sbjct: 865 KNANEKTRLENQ 876



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 18/77 (23%), Positives = 42/77 (54%), Gaps = 3/77 (3%)

Query: 92  IRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV 151
           +RS+    ++ L+K  EE  + Q   +   ++LK +    DNVK L++ ++++    ++ 
Sbjct: 141 VRSKYSEDKANLQKQLEEAMNTQ---LELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQ 197

Query: 152 ETELQRRNEETPEEGQQ 168
              LQ++ + T +E ++
Sbjct: 198 ILYLQKQLDATTDEKKE 214


>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a-like [Homo sapiens]
          Length = 432

 Score = 31.6 bits (70), Expect = 0.85
 Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 16/126 (12%)

Query: 39  PRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGN 98
           P   P K         H R+ L+S+       G  L  E+  + M+ +    R   ++  
Sbjct: 152 PPAGPSKVEQLQDETNHLRKELESV-------GRQLQAEVENNQML-SLLNRRQEERLRE 203

Query: 99  TESELKKLAEENPDLQEAYIAKQKRLKS---KLLDHDNVKYLKKILDELEKVLDQVETEL 155
            E  L++  E   + +E    +++RL+    +L + + +   +++L+E+EK+L Q     
Sbjct: 204 QEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQ----- 258

Query: 156 QRRNEE 161
           +RR EE
Sbjct: 259 ERRQEE 264


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 31.6 bits (70), Expect = 0.85
 Identities = 23/118 (19%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 58  ELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDL-QEA 116
           E LD    +A  H  ++  +L+          ++++  + + +  + +L ++  D+ +E 
Sbjct: 498 EELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKEL 557

Query: 117 YIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV------ETELQRRNEETPEEGQQ 168
            + K+K ++S++  +D     +K+ D++E ++DQ+         +Q+ N E  E  +Q
Sbjct: 558 DVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQ 615


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 31.6 bits (70), Expect = 0.85
 Identities = 31/94 (32%), Positives = 38/94 (40%), Gaps = 18/94 (19%)

Query: 98  NTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQR 157
           NT  ++KKL      LQ A    QK  K +  D          +DELEK +  VE   Q 
Sbjct: 304 NTSHKIKKLEAAKKSLQNA----QKHYKKRKGD----------MDELEKEMLSVEKARQE 349

Query: 158 RNEETPEEGQQPWLCGESFTLADVSLAVTLHRLK 191
             E   EE Q     G   TL + +     HRLK
Sbjct: 350 FEERMEEESQSQ---GRDLTLEE-NQVKKYHRLK 379


>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
          Length = 432

 Score = 31.6 bits (70), Expect = 0.85
 Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 16/126 (12%)

Query: 39  PRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGN 98
           P   P K         H R+ L+S+       G  L  E+  + M+ +    R   ++  
Sbjct: 152 PPAGPSKVEQLQDETNHLRKELESV-------GRQLQAEVENNQML-SLLNRRQEERLRE 203

Query: 99  TESELKKLAEENPDLQEAYIAKQKRLKS---KLLDHDNVKYLKKILDELEKVLDQVETEL 155
            E  L++  E   + +E    +++RL+    +L + + +   +++L+E+EK+L Q     
Sbjct: 204 QEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQ----- 258

Query: 156 QRRNEE 161
           +RR EE
Sbjct: 259 ERRQEE 264


>gi|66346733 chloride intracellular channel 2 [Homo sapiens]
          Length = 247

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 42/182 (23%), Positives = 71/182 (39%), Gaps = 58/182 (31%)

Query: 10  PVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYT 69
           P L++ + +  +  +I ++LEQT    R P L P            Y+E  D        
Sbjct: 71  PFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSP-----------KYKESFDV------- 112

Query: 70  HGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLL 129
            GC L                +  + I NT+       E N + +++ + + KRL     
Sbjct: 113 -GCNLF--------------AKFSAYIKNTQK------EANKNFEKSLLKEFKRLDD--- 148

Query: 130 DHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHR 189
                 YL   L      LD+++ +    + E P   ++ +L G+  TLAD SL   L+ 
Sbjct: 149 ------YLNTPL------LDEIDPD----SAEEPPVSRRLFLDGDQLTLADCSLLPKLNI 192

Query: 190 LK 191
           +K
Sbjct: 193 IK 194


>gi|131889097 cancer susceptibility candidate 1 isoform b [Homo
           sapiens]
          Length = 716

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 26/126 (20%), Positives = 47/126 (37%), Gaps = 16/126 (12%)

Query: 37  RTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQI 96
           R+ R    +     PR+    ++   L    Y H   LHP  T      +  T  ++  +
Sbjct: 226 RSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDV 285

Query: 97  GNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQ 156
            N E  + K  EE         +KQ+   S L+  + +K        +E+    +E ++ 
Sbjct: 286 KNVEKAISKEVEEE--------SKQQERGSHLIQEEEIK--------VEEEQGDIEVKMS 329

Query: 157 RRNEET 162
              EE+
Sbjct: 330 SAEEES 335


>gi|131889447 cancer susceptibility candidate 1 isoform c [Homo
           sapiens]
          Length = 690

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 26/126 (20%), Positives = 47/126 (37%), Gaps = 16/126 (12%)

Query: 37  RTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQI 96
           R+ R    +     PR+    ++   L    Y H   LHP  T      +  T  ++  +
Sbjct: 290 RSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDV 349

Query: 97  GNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQ 156
            N E  + K  EE         +KQ+   S L+  + +K        +E+    +E ++ 
Sbjct: 350 KNVEKAISKEVEEE--------SKQQERGSHLIQEEEIK--------VEEEQGDIEVKMS 393

Query: 157 RRNEET 162
              EE+
Sbjct: 394 SAEEES 399


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,614,741
Number of Sequences: 37866
Number of extensions: 462719
Number of successful extensions: 2299
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 2150
Number of HSP's gapped (non-prelim): 283
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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