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Search of human proteins with 4505995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 968 0.0
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 778 0.0
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 775 0.0
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 661 0.0
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 596 e-170
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 596 e-170
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 517 e-146
gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens] 375 e-104
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 300 1e-81
gi|4505999 protein phosphatase 1G [Homo sapiens] 128 1e-29
gi|29826282 protein phosphatase 1G [Homo sapiens] 128 1e-29
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 126 5e-29
gi|13540531 integrin-linked kinase-associated protein phosphatas... 113 3e-25
gi|30089948 protein phosphatase 1E [Homo sapiens] 104 2e-22
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 101 1e-21
gi|7661862 protein phosphatase 1F [Homo sapiens] 99 1e-20
gi|4505997 protein phosphatase 1D [Homo sapiens] 86 6e-17
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 59 7e-09
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 57 4e-08
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 55 1e-07
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 55 1e-07
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 53 7e-07
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 50 6e-06
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|37221175 PH domain and leucine rich repeat protein phosphatas... 48 2e-05
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 36 0.068
gi|157785645 SPEG complex locus [Homo sapiens] 33 0.44
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 968 bits (2502), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
Query: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR
Sbjct: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
Query: 361 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL 420
NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL
Sbjct: 361 NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL 420
Query: 421 AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI 479
AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
Sbjct: 421 AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI 479
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 778 bits (2010), Expect = 0.0
Identities = 379/385 (98%), Positives = 382/385 (99%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
Query: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR
Sbjct: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
Query: 361 NVIEAVYSRLNPHRESDGASDEAEE 385
NVIEAVYSRLNPHRESDG + + E+
Sbjct: 361 NVIEAVYSRLNPHRESDGGAGDLED 385
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 775 bits (2002), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
Query: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR
Sbjct: 301 VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR 360
Query: 361 NVIEAVYSRLNPHRESDG 378
NVIEAVYSRLNPHRESDG
Sbjct: 361 NVIEAVYSRLNPHRESDG 378
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 661 bits (1706), Expect = 0.0
Identities = 321/321 (100%), Positives = 321/321 (100%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
Query: 301 VSDEAVKKDSELDKHLESRVE 321
VSDEAVKKDSELDKHLESRVE
Sbjct: 301 VSDEAVKKDSELDKHLESRVE 321
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 596 bits (1536), Expect = e-170
Identities = 293/386 (75%), Positives = 335/386 (86%), Gaps = 7/386 (1%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGS+VA YC HLL+HIT N+DF+ GSA SVENVKNGIRTGFL+IDE+MR
Sbjct: 61 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
Query: 300 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK 359
KVS EAVKK++ELDK+LE RVEEI++K G EG+PDL HVMR L++ENIP+LPPGG LA K
Sbjct: 296 KVSPEAVKKEAELDKYLECRVEEIIKKQG-EGVPDLVHVMRTLASENIPSLPPGGELASK 354
Query: 360 RNVIEAVYSRLNPHRESDGASDEAEE 385
RNVIEAVY+RLNP++ D S ++
Sbjct: 355 RNVIEAVYNRLNPYKNDDTDSTSTDD 380
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 596 bits (1536), Expect = e-170
Identities = 293/386 (75%), Positives = 335/386 (86%), Gaps = 7/386 (1%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 74 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 133
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGS+VA YC HLL+HIT N+DF+ GSA SVENVKNGIRTGFL+IDE+MR
Sbjct: 134 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 188
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 189 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 248
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 249 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 308
Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 309 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 368
Query: 300 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK 359
KVS EAVKK++ELDK+LE RVEEI++K G EG+PDL HVMR L++ENIP+LPPGG LA K
Sbjct: 369 KVSPEAVKKEAELDKYLECRVEEIIKKQG-EGVPDLVHVMRTLASENIPSLPPGGELASK 427
Query: 360 RNVIEAVYSRLNPHRESDGASDEAEE 385
RNVIEAVY+RLNP++ D S ++
Sbjct: 428 RNVIEAVYNRLNPYKNDDTDSTSTDD 453
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 517 bits (1331), Expect = e-146
Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)
Query: 1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
Query: 61 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
GHAGS+VA YC HLL+HIT N+DF+ GSA SVENVKNGIRTGFL+IDE+MR
Sbjct: 61 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
Query: 300 KVSDEAVKKDSELDKHLESRVE 321
KVS EAVKK++ELDK+LE RVE
Sbjct: 296 KVSPEAVKKEAELDKYLECRVE 317
>gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]
Length = 192
Score = 375 bits (964), Expect = e-104
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 288 MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENI 347
MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENI
Sbjct: 1 MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENI 60
Query: 348 PNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNY 407
PNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNY
Sbjct: 61 PNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNY 120
Query: 408 RQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSN 467
RQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSN
Sbjct: 121 RQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSN 180
Query: 468 EDAGTKMSGEKI 479
EDAGTKMSGEKI
Sbjct: 181 EDAGTKMSGEKI 192
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 300 bits (769), Expect = 1e-81
Identities = 168/378 (44%), Positives = 226/378 (59%), Gaps = 20/378 (5%)
Query: 13 HNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCS 72
H A GLR+G S+ QGWR MEDAH + +P W+ FAV DGH G+R A + +
Sbjct: 56 HGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGA 115
Query: 73 THLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGS 132
HL H+ + G S E V+ +R FL DE +R+ L ++ G
Sbjct: 116 RHLPGHV-----LQELGPEPS----EPEGVREALRRAFLSADERLRS---LWPRVETGGC 163
Query: 133 TAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRV 192
TAV +++SP+ +Y +CGDSRAVL R G V FST+DH+P PRE+ERI AGG++ +RV
Sbjct: 164 TAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRV 223
Query: 193 NGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNE 252
GSLAVSRALGD+ YK G+ P QLVS EPEV + R EDEF++LA DG+WD +S
Sbjct: 224 EGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGA 283
Query: 253 ELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSEL 312
L V SRL + E +C ++DTCL KGS DNM+ +LVCF AP+ S+EA++++ L
Sbjct: 284 ALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELAL 343
Query: 313 DKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNP 372
D L R+ E+ + + P L V R L++E+IP+LPPGGGL K VI VYS++
Sbjct: 344 DAALGCRIAELC--ASAQKPPSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQ 401
Query: 373 HRESDGASDEAEESGSQG 390
S+E E G G
Sbjct: 402 ------VSEECGEKGQDG 413
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 128 bits (321), Expect = 1e-29
Identities = 73/216 (33%), Positives = 123/216 (56%), Gaps = 25/216 (11%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189
SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V +
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386
Query: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248
RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V
Sbjct: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446
Query: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296
MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF
Sbjct: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506
Query: 297 --NAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE 330
N ++ E+ K+ ++EE++ G E
Sbjct: 507 PRNTAELQPESGKR----------KLEEVLSTEGAE 532
Score = 75.1 bits (183), Expect = 1e-13
Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%)
Query: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57
MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+
Sbjct: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57
Query: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96
VYDGH G VA YC+ +L + I + ++ GK ALE
Sbjct: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 128 bits (321), Expect = 1e-29
Identities = 73/216 (33%), Positives = 123/216 (56%), Gaps = 25/216 (11%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189
SG+TAV +I K + N GDSR V+ G+ + DHKP + E RI+NAGG V +
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386
Query: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248
RVNG L +SRA+GD+ YK P EQ++S P++ + ++ EF+++ACDGIW+V
Sbjct: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446
Query: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296
MS++E+ ++++S++ D+ L ++ ++D CL + DNM+ +++CF
Sbjct: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506
Query: 297 --NAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEE 330
N ++ E+ K+ ++EE++ G E
Sbjct: 507 PRNTAELQPESGKR----------KLEEVLSTEGAE 532
Score = 75.1 bits (183), Expect = 1e-13
Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%)
Query: 1 MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57
MGA+L +P T K + G G L YG S+MQGWRV MEDAH IP + + F+
Sbjct: 1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57
Query: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96
VYDGH G VA YC+ +L + I + ++ GK ALE
Sbjct: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 126 bits (316), Expect = 5e-29
Identities = 89/282 (31%), Positives = 140/282 (49%), Gaps = 23/282 (8%)
Query: 28 SMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRA 87
S+QG R MED + + + S F ++DGH G A Y + L E + +
Sbjct: 97 SIQGRRDHMEDRFEVLTDLANKTHP-SIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYE 155
Query: 88 AGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFI 147
K S L + + + L ID M L D +G+T + ++S K +
Sbjct: 156 KDKENSVL-----SYQTILEQQILSIDREM--LEKLTVSYDEAGTTCLIALLSDKDLTVA 208
Query: 148 NCGDSRAVLY-RNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSLAVSRALG 203
N GDSR VL ++G + DHKP +E++RI+ AGG + RV G LA+SR+LG
Sbjct: 209 NVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLG 268
Query: 204 DYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELCEYVKSRL 262
DY K ++ +V P+P++ L + EF+ILA DG+WD SNEE ++K RL
Sbjct: 269 DYPLKNLN-------VVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERL 321
Query: 263 EVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDE 304
D+ +V ++G DN+++++V F N+ K ++
Sbjct: 322 ---DEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ 360
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 113 bits (283), Expect = 3e-25
Identities = 88/299 (29%), Positives = 138/299 (46%), Gaps = 42/299 (14%)
Query: 21 GLRYGLSSMQGWRVEMEDAHTAVVGIPHG-------LEDWSFFAVYDGHAGSRVANYCST 73
GL+ ++ +G R EM+DAH + I + S+FAV+DGH G R + + +
Sbjct: 106 GLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQ 165
Query: 74 HLLEHITTNEDFRAAGKSGSALELSVEN-VKNGIRTGFLKIDEYMRNFSDLRNGMDRSGS 132
+L +++ K +SVE VK + F DE + + + GS
Sbjct: 166 NLHQNLIR--------KFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGS 217
Query: 133 TAVGVMISPKHIYFINCGDSRAVLYRNGQ------VCFSTQDHKPCNPREKERIQNAGGS 186
TA V+ +Y N GDSRA+L R + +++H P E+ RIQ AGG+
Sbjct: 218 TATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGN 277
Query: 187 VMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIW 246
V RV G L VSR++GD YK V+ P++ D FI+LACDG++
Sbjct: 278 VRDGRVLGVLEVSRSIGDGQYKRCG--------VTSVPDIRRCQLTPNDRFILLACDGLF 329
Query: 247 DVMSNEELCEYVKSRLE------------VSDDLENVCNWVVDTCLHKGSRDNMSIVLV 293
V + EE ++ S LE E CN + + + +GS DN+++++V
Sbjct: 330 KVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVV 388
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 104 bits (259), Expect = 2e-22
Identities = 103/364 (28%), Positives = 161/364 (44%), Gaps = 57/364 (15%)
Query: 26 LSSMQGWRVEMEDAHTAV--VGIPHGLEDW---SFFAVYDGHAGSRVANYCSTHLLEHIT 80
+ +++ R +MED H + + LED ++FAV+DGH G A Y S HL ++
Sbjct: 234 IHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLV 293
Query: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMIS 140
E F + + F DE R R G+T V I
Sbjct: 294 RQEMFP-------------HDPAEALCRAFRVTDE--RFVQKAARESLRCGTTGVVTFIR 338
Query: 141 PKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSLA 197
++ GDS+ +L R GQ + HKP EK+RI+ GG V+ RVNGSL+
Sbjct: 339 GNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLS 398
Query: 198 VSRALGDYDYK---CVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEEL 254
VSRA+GD ++K C D + L E +++ILACDG +D ++ +E
Sbjct: 399 VSRAIGDAEHKPYICGDADSASTVLDGTE------------DYLILACDGFYDTVNPDEA 446
Query: 255 CEYVKSRL-EVSDDLENVCNWVVDTCLHKGSRDNMSIVLVC---FSNAPKVSDEAVKKDS 310
+ V L E + D V + +V + GS DN+++++V + A VS+E+ ++
Sbjct: 447 VKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTEN 506
Query: 311 ELDKHLESRVEEIMEKSGEEGMP----------DLAHVMRILSAENIPNLPPGGGLAGKR 360
E ++ E GE P DL + R+ S + +L PG +
Sbjct: 507 SFQGGQEDGGDD-KENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQI---- 561
Query: 361 NVIE 364
NV+E
Sbjct: 562 NVLE 565
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 101 bits (252), Expect = 1e-21
Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 25 GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
G +S G R E ED ++ +FAVYDGH G A++C TH+ + I
Sbjct: 96 GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148
Query: 85 FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
L +N++ + FL+ID+ + + L SG+TA V ++
Sbjct: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198
Query: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
+ + GDSRA+L R G+ T DH P EKERI+ GG S+ VNG L
Sbjct: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258
Query: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
A++R++GD D K V EPE I L +D F++L DGI +++++E+C
Sbjct: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310
Query: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
++V D + V + + G+ DN + V+V F
Sbjct: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 98.6 bits (244), Expect = 1e-20
Identities = 82/308 (26%), Positives = 143/308 (46%), Gaps = 37/308 (12%)
Query: 26 LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
+ +++ R +MED H ++ GL D ++FAV+DGH G A Y + H+ +
Sbjct: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218
Query: 81 TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
+ + + +R F + D+ ++R R +SG+T V +I
Sbjct: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262
Query: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
+ ++ GDS+ +L + GQV + H+P EK RI+ GG V RVNG+L
Sbjct: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322
Query: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
AVSRA+GD K VS E + +++++LACDG +DV+ ++E+
Sbjct: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373
Query: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKH 315
V+S L V +V +GS DN+++++V + ++ + E D
Sbjct: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG--NQGEGDPQ 431
Query: 316 LESRVEEI 323
E R +++
Sbjct: 432 AEGRRQDL 439
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 86.3 bits (212), Expect = 6e-17
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)
Query: 54 SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
+FFAV DGH G A + HL I + F ++ + V IR GFL
Sbjct: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149
Query: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
K+ E+ + + L + SG+TA V+I +Y + GDS VL
Sbjct: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206
Query: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
+ TQDHKP P+E+ERI+ GGSVM + RV NG
Sbjct: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266
Query: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
LAV+RALGD + Y G E +VSPEP+ L ++ ++IIL DG+W+++
Sbjct: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
Query: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
++ + + E + + ++ +V+ L + + DN S +++C S P+V
Sbjct: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380
Query: 303 DE 304
++
Sbjct: 381 NQ 382
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 59.3 bits (142), Expect = 7e-09
Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)
Query: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
G TA+ V+ +Y N GDSRA++ RNG++ + + P R++
Sbjct: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327
Query: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
R+Q G M+ R V ++
Sbjct: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387
Query: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
V+R LGD+D K D + +S PEV Y++ + + D+ +ILA DG+WDV+SNEE
Sbjct: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447
Query: 254 LCEYVKSRLEVSD 266
+ E + L D
Sbjct: 448 VAEAITQFLPNCD 460
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 57.0 bits (136), Expect = 4e-08
Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)
Query: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
DE RN S + SG+TA + H++ N GD RA+L NG C T+D
Sbjct: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308
Query: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
H N E R++ +M R+ G L RA GD K ++
Sbjct: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368
Query: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
TE L ++ EPEV Y LR + D+F++LA DG+WD++SNE++ V
Sbjct: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427
Query: 259 KSRLEVSD 266
L +D
Sbjct: 428 VGHLAEAD 435
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 55.1 bits (131), Expect = 1e-07
Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
Query: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246
R+ G+LAVSR LGD+ + +D + + P+V + L +ED+ +++A DG+W
Sbjct: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
Query: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289
DV+SNE++ V+S L + + + + + +H +G D+++
Sbjct: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 55.1 bits (131), Expect = 1e-07
Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)
Query: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246
R+ G+LAVSR LGD+ + +D + + P+V + L +ED+ +++A DG+W
Sbjct: 167 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 226
Query: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289
DV+SNE++ V+S L + + + + + +H +G D+++
Sbjct: 227 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 271
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 52.8 bits (125), Expect = 7e-07
Identities = 65/295 (22%), Positives = 108/295 (36%), Gaps = 95/295 (32%)
Query: 55 FFAVYDGHAGSRVANYCSTHLLEHIT----------------------------TNEDFR 86
++ ++DGHAG A S L HI +++
Sbjct: 153 YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPSH 212
Query: 87 AAGKSG---SALELSVENVKNG-IRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPK 142
G S E+S E++ G + F +DE M + R G A+ V+
Sbjct: 213 LLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMAR--ERRGHQVEGGCCALVVIYLLG 270
Query: 143 HIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAG------------------ 184
+Y N GDSRA++ RNG++ +++ P E++R+Q G
Sbjct: 271 KVYVANAGDSRAIIVRNGEIIPMSREFTP--ETERQRLQLLGFLKPELLGSEFTHLEFPR 328
Query: 185 -------GSVMIQR------------------------------VNGSLAVSRALGDYDY 207
G M+ R V ++ V+R LGD+
Sbjct: 329 RVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSL 388
Query: 208 KCVDGKGPTEQLVS--PEPEVYEILRAEE--DEFIILACDGIWDVMSNEELCEYV 258
K P + +S PE VY++ + E D+ ++L DG+WDV ++ E+ V
Sbjct: 389 KVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATV 443
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329
Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
A V R+ G L RA GD +K V GP
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389
Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 390 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 433
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329
Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
A V R+ G L RA GD +K V GP
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389
Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 390 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 433
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
A V R+ G L RA GD +K V GP
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
A V R+ G L RA GD +K V GP
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 329 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 388
Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
A V R+ G L RA GD +K V GP
Sbjct: 389 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 448
Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 449 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 492
>gi|37221175 PH domain and leucine rich repeat protein phosphatase
[Homo sapiens]
Length = 1205
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/150 (28%), Positives = 65/150 (43%), Gaps = 14/150 (9%)
Query: 148 NCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ-RVNGSLAVSRALGDYD 206
N G + VL RNG+ ++ + E +RI+ + +VNG +R LG Y
Sbjct: 775 NVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILG-YT 833
Query: 207 YKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSD 266
+ V P P V +L +DEF IL G+WD +S EE E V++ +
Sbjct: 834 F--------LHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALA 885
Query: 267 DLENVCNWVVDTCLHKGSRDNMSIVLVCFS 296
+ +C G D++S V+V S
Sbjct: 886 AAKKLCT----LAQSYGCHDSISAVVVQLS 911
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 36.2 bits (82), Expect = 0.068
Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 11/127 (8%)
Query: 356 LAGKRNVIEAVYSRLNPHRESDGASDEA-------EESGSQGKLVEALRQMRINHRGNYR 408
L+ ++N++ A+ S RE+ G S +GS+G + +R +
Sbjct: 614 LSDEQNIL-ALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIK 672
Query: 409 QLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNE 468
+LE+ + R +V+ PA+P++ + S NSD +Q++ E E+ A LD + +
Sbjct: 673 SILEQ---AKRELQVQKTAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALK 729
Query: 469 DAGTKMS 475
A S
Sbjct: 730 QAPLSQS 736
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/59 (35%), Positives = 28/59 (47%)
Query: 417 SYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMS 475
S R+ K PA+PAAT TS + PV +++ TE + G S AGT S
Sbjct: 313 SPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAES 371
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,074,567
Number of Sequences: 37866
Number of extensions: 878340
Number of successful extensions: 2428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 2317
Number of HSP's gapped (non-prelim): 100
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.