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Search of human proteins with 4502719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502719 cadherin 13 preproprotein [Homo sapiens]
(713 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 1426 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 520 e-147
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 482 e-136
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 396 e-110
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 379 e-105
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 371 e-102
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 342 9e-94
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 342 9e-94
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 330 2e-90
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 330 2e-90
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 307 3e-83
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 307 3e-83
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 304 2e-82
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 278 1e-74
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 278 1e-74
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 267 3e-71
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 267 3e-71
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 256 7e-68
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 253 4e-67
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 245 1e-64
gi|221316595 cadherin 17 precursor [Homo sapiens] 238 2e-62
gi|221316593 cadherin 17 precursor [Homo sapiens] 238 2e-62
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 237 2e-62
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 237 2e-62
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 232 8e-61
gi|16753221 cadherin 22 precursor [Homo sapiens] 231 1e-60
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 231 2e-60
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 225 1e-58
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 225 1e-58
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 219 5e-57
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 1426 bits (3691), Expect = 0.0
Identities = 713/713 (100%), Positives = 713/713 (100%)
Query: 1 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG 60
MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG
Sbjct: 1 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG 60
Query: 61 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS 120
NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS
Sbjct: 61 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS 120
Query: 121 LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV 180
LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV
Sbjct: 121 LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV 180
Query: 181 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND 240
DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND
Sbjct: 181 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND 240
Query: 241 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY 300
NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY
Sbjct: 241 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY 300
Query: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS
Sbjct: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
Query: 361 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN 420
PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN
Sbjct: 361 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN 420
Query: 421 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD 480
EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD
Sbjct: 421 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD 480
Query: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD
Sbjct: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS 600
RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS
Sbjct: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS 600
Query: 601 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM 660
VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM
Sbjct: 601 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM 660
Query: 661 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL 713
VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
Sbjct: 661 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL 713
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 520 bits (1338), Expect = e-147
Identities = 302/707 (42%), Positives = 420/707 (59%), Gaps = 27/707 (3%)
Query: 4 RTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDK 63
RT L L L Q + S E C GF + V+ + E Q +LN+ FS+C G K
Sbjct: 9 RTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCNGKRK 68
Query: 64 LRYEVSSPY-FKVNSDGGLVALRN--ITAVGKTLFVHARTPHAEDMAELVI-------VG 113
++YE S P FKV+ DG + A+R+ +++ ++A+ ++ ++ + +
Sbjct: 69 VQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLT 128
Query: 114 GKDIQGSLQ-DIFKFAR-----TSPVPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSD 166
+ ++ S + + F R + + RQKR V+ PI +PEN R PFP+++ ++ D D
Sbjct: 129 EESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRD 188
Query: 167 RPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLE 226
+ ++ +TG G DQ P GIF IN +G +SVT+ LDRE IA + L D+NG +E
Sbjct: 189 KNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVE 248
Query: 227 GPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNI 286
P+ + + VID NDNRP F + G V EGS GT VM +TA DADDP N +LRY I
Sbjct: 249 NPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRI 308
Query: 287 RQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDV-GLTG 345
Q P PSPNMF I+ E GDI+TV A LDRE ++ +Y LII+A DM G GL+
Sbjct: 309 VSQAPSTPSPNMFTINNETGDIITVA--AGLDREKVQ--QYTLIIQATDMEGNPTYGLSN 364
Query: 346 TATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIIN 404
TATA I + D ND+ P+FT F V E V +IV NLTV DKD P T AW A Y I
Sbjct: 365 TATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISG 424
Query: 405 GNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATV 464
G+P F I T+P +N+G+++VVKP+D+E + L + EN+ PL + + P STATV
Sbjct: 425 GDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATV 484
Query: 465 HITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWL 524
+TV+DVNE P F P+P ++ ++E L G++L T A DPD Q IRY+ DPA WL
Sbjct: 485 SVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWL 544
Query: 525 NINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPF 584
I+P+NG + T AVLDRESP V N++Y A FLA D+G PP +GTGTL I L D+NDNAP
Sbjct: 545 KIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ 604
Query: 585 IYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDK-VWKISKINNTHAL 643
+ P AE C+ S+ I A D D+ PN PF F++ V K W I+++N A
Sbjct: 605 VLPQEAETCETPDPNSINIT-ALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQ 663
Query: 644 VSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDC 689
++L ++ L Y +PI++TDSG PP +NI+ LRV+VC C +S DC
Sbjct: 664 LNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQC-DSNGDC 709
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 482 bits (1240), Expect = e-136
Identities = 288/725 (39%), Positives = 407/725 (56%), Gaps = 43/725 (5%)
Query: 8 VLCVLLS-QVLLLTSAEDLD----CTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGND 62
VL +LLS L EDL C GF + + +E + +L + FS C G
Sbjct: 7 VLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTK 66
Query: 63 KLRYEVSSPYFKVNSDGGLVALRNIT----------------------AVGKTLFVHART 100
+YE +S FKV +DG + A R + AV + L +
Sbjct: 67 GTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSS 126
Query: 101 PHAEDMAE-----LVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPF 155
PH+ + + + + +L + + + R+KR V+ PI +PEN R PF
Sbjct: 127 PHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPF 186
Query: 156 PRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLF 214
P+ + ++ D D ++ +TG G DQ P +F I+ +G + VTR +DRE A Y L
Sbjct: 187 PQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLR 246
Query: 215 VETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADD 274
D+NG +E P+ L + VID NDNRP F Y G V EGS GT VM +TA DADD
Sbjct: 247 AHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADD 306
Query: 275 PATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQ 334
T N ++RY I QTP PS NMF I+ E GDIVTV A LDRE ++ +Y +I++A
Sbjct: 307 STTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVA--AGLDREKVQ--QYTVIVQAT 362
Query: 335 DMAG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPT 392
DM G L+ GL+ TATA I + D ND+ P+FT F V E V +V NLTV D+D P
Sbjct: 363 DMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPH 422
Query: 393 TGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVP 452
+ W A Y II+G+P F + T+P TNEGM++VVK +DYE++ L + V N+ PL
Sbjct: 423 SPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLAS 482
Query: 453 DVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTI 512
+ STA V I+++D+NE P F + ++ +E + G+VL T +A DPD Q +
Sbjct: 483 GIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAV 542
Query: 513 RYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLL 572
RYS DPA WL+IN NG + T AVLDRES + N+VY A FLA D+G PPA+GTGTL
Sbjct: 543 RYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602
Query: 573 ITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEI-HKQAVPDKV 631
I L D+NDNAP + P A++C + NL+ + + A+D D+ PN P+ FE+ A K
Sbjct: 603 IYLIDINDNAPELLPKEAQIC-EKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKN 661
Query: 632 WKISKINNTHALVSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCN 690
W I+++N +A +SL + L Y++PI+VTDSG PP++N + ++V+VC C + DC
Sbjct: 662 WTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPC-DDNGDCT 720
Query: 691 AAGAL 695
GA+
Sbjct: 721 TIGAV 725
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 396 bits (1018), Expect = e-110
Identities = 258/716 (36%), Positives = 366/716 (51%), Gaps = 39/716 (5%)
Query: 11 VLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILN-LTFSDCKGNDKLRYEVS 69
+LL QV E C PGF + + P +E +L + F DC G + Y
Sbjct: 12 LLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSL 71
Query: 70 SPYFKVNSDGGLVALRNITAVGKTL--FVHARTPHAEDMAELVIVGG-----------KD 116
FKV +DG + R + + V+A + V +
Sbjct: 72 DTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQAS 131
Query: 117 IQGSLQDIFKFARTSP-VPRQKRSIVVSPILIPENQRQPFPRDVGKVVDS-DRPERSKFR 174
+ G ++ F +SP + RQKR V+ PI PEN++ PFP+++ ++ + D+ + +
Sbjct: 132 VSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYS 191
Query: 175 LTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVI 234
+TG+G D P G+F I TG + VT LDRE IA Y LF NG +E P+ + +
Sbjct: 192 ITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILIT 251
Query: 235 VIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPA-TDNALLRYNIRQQTPDK 293
V DQNDN+P F + + G VMEG+ GT+VM +TA DADD T NA + Y I Q P+
Sbjct: 252 VTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPEL 311
Query: 294 PSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMI 353
P NMF I+ G +++VV+ LDRE+ P Y L+++A D+ G GL+ TATA I +
Sbjct: 312 PDKNMFTINRNTG-VISVVTTG-LDRESF--PTYTLVVQAADLQG--EGLSTTATAVITV 365
Query: 354 DDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFE 412
D ND+ P F ++ V E V++ L V D D P T AW A YTI+N + GQ F
Sbjct: 366 TDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FV 424
Query: 413 IHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVN 472
+ TNP N+G+L K LD+E + L + V N P ++ +STATV + VLDVN
Sbjct: 425 VTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT---TSTATVTVDVLDVN 481
Query: 473 EGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGT 532
E P+F P V ED VG + + A +PD+ Q I Y +++D A WL INP G
Sbjct: 482 EAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGA 541
Query: 533 VDTTAVLDRES-PFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAE 591
+ T A LDRE V NS YTAL +A D+G+P ATGTGTLL+ L DVNDNAP P
Sbjct: 542 ISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIF 601
Query: 592 VCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQN-- 649
C+ +N ++ D DL PNT PF E+ A + W I + T + L
Sbjct: 602 FCE--RNPKPQVINIIDADLPPNTSPFTAELTHGASAN--WTIQYNDPTQESIILKPKMA 657
Query: 650 LNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALR--FSLPSVL 703
L +Y + + + D+ +T L V VC C + C A + +P++L
Sbjct: 658 LEVGDYKINLKLMDNQN--KDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAIL 711
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 379 bits (973), Expect = e-105
Identities = 258/719 (35%), Positives = 375/719 (52%), Gaps = 57/719 (7%)
Query: 3 PRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGND 62
PR PL +LL QV L A C F++ + E L F C G +
Sbjct: 4 PRGPLASLLLL-QVCWLQCAASEPCRAVFREAEVTLEAGGAEQEPGQALGKVFMGCPGQE 62
Query: 63 KLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQ 122
+ + F V RN V + + R P L I K I
Sbjct: 63 PALFSTDNDDFTV---------RNGETVQERRSLKERNP-------LKIFPSKRI----- 101
Query: 123 DIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDS-DRPERSKFRLTGKGVD 181
+ R KR VV+PI +PEN + PFP+ + ++ + DR + + +TG G D
Sbjct: 102 ----------LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGAD 151
Query: 182 QEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDN 241
P+G+F + + TG + + + LDRE IA Y+LF NG ++E P+ + +IV DQND+
Sbjct: 152 SPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDH 211
Query: 242 RPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPA-TDNALLRYNIRQQTPDKPSPNMFY 300
+P F + + G V+EG GT+VM++TA D DD T N ++ Y+I Q P P MF
Sbjct: 212 KPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFT 271
Query: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
I G I + S LDRE + P+Y L I+A DM G G T TA A + I D ND++
Sbjct: 272 IHRSTGTISVISSG--LDREKV--PEYTLTIQATDMDG--DGSTTTAVAVVEILDANDNA 325
Query: 361 PKFTKKEFQATVEEGAVG-VIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQT 419
P F ++++A V E AVG + LTV D D P + AWRA Y I+ G+ G F I T+P++
Sbjct: 326 PMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPES 385
Query: 420 NEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYP 479
N+G+L+ K LD+E HTL ++V NE P V + P+STAT+ + V DVNE PVF P
Sbjct: 386 NQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKL---PTSTATIVVHVEDVNEAPVFVP 442
Query: 480 DPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVL 539
+V QE + G + A DPD ++Q I Y + +DPAGWL ++P +G V L
Sbjct: 443 PSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTL 501
Query: 540 DRE-SPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKN 598
DRE FV N++Y + LA+D+G+PP TGTGTLL+TL DVND+ P P +C+ +
Sbjct: 502 DREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPV 561
Query: 599 LSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVW--KISKINNTHALVSLLQNLNKANYN 656
V L +DKDL P+T PF+ ++ + D W ++++ +T ++SL + L + Y+
Sbjct: 562 RQV--LNITDKDLSPHTSPFQAQLTDDS--DIYWTAEVNEEGDT-VVLSLKKFLKQDTYD 616
Query: 657 LPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLP--SVLLLSLFSLACL 713
+ + ++D G +T +R VC C C F LP +L LF L L
Sbjct: 617 VHLSLSDHGN--KEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLGAVLALLFLLLVL 673
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 371 bits (953), Expect = e-102
Identities = 224/579 (38%), Positives = 326/579 (56%), Gaps = 21/579 (3%)
Query: 124 IFKFARTSPVPRQKRSIVVSPILIPEN-QRQPFPRDVGKVVDSDRPERSK--FRLTGKGV 180
++ + R + R +R+ V+ PI + EN +R P+P + SD+ + + + G GV
Sbjct: 31 LYPWRRAPALSRVRRAWVIPPISVSENHKRLPYPL---VQIKSDKQQLGSVIYSIQGPGV 87
Query: 181 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND 240
D+EP+G+F I++ TG V + LDRE ++L D+ G TLE P LE++V+DQND
Sbjct: 88 DEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQND 147
Query: 241 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY 300
NRP F + + G V+EG+ GT V R A DADDP TDNA LR++I QQ SP +F
Sbjct: 148 NRPAFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQG----SPELFS 203
Query: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
ID G+I TV LDRE + Y L ++ DM+G GLT TA+A I +DD ND++
Sbjct: 204 IDELTGEIRTV--QVGLDREVVA--VYNLTLQVADMSG--DGLTATASAIITLDDINDNA 257
Query: 361 PKFTKKEFQATVEEGAVGVIVN-LTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQT 419
P+FT+ EF E GV V L VED+D P + W A +TI+ G+P F I T+P+T
Sbjct: 258 PEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKT 317
Query: 420 NEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYP 479
NEG+LS+VK LDYE + L + V+NE PL A V + V D NE PVF
Sbjct: 318 NEGVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQE 377
Query: 480 DPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVL 539
+P+ + E G+++ T +A DPD+ Q Q + YS DP WL ++ G + T VL
Sbjct: 378 NPLRTSLAEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVL 437
Query: 540 DRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIY-PTVAEVCDDAKN 598
SPF+ Y A+ LA D + P T TGTL I + +VND+AP + P +C +
Sbjct: 438 SPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQ 497
Query: 599 LSVVILGASDKDLHPNTDPFKFEIHKQAVPD--KVWKISKINNTHALVSLLQNLNKANYN 656
++LGA+D+DL P+ PF F++ + +P+ + W +S++N +HA + + + +
Sbjct: 498 GPGLLLGATDEDLPPHGAPFHFQLSPR-LPELGRNWSLSQVNVSHARLRPRHQVPEGLHR 556
Query: 657 LPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGAL 695
L +++ DSG+PP L V VC C V A AL
Sbjct: 557 LSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAAL 595
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 342 bits (876), Expect = 9e-94
Identities = 224/655 (34%), Positives = 346/655 (52%), Gaps = 30/655 (4%)
Query: 38 INQPAEFIEDQSILNLTFSDC-KGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGK---- 92
+N P++ D+ I + +C + D +R S P F+V +DG + R + K
Sbjct: 37 LNVPSKLEADKIIGRVNLEECFRSADLIRS--SDPDFRVLNDGSVYTARAVALSDKKRSF 94
Query: 93 TLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQR 152
T+++ + + +++ K + + + R + + R KR P + EN
Sbjct: 95 TIWLSDKRKQTQKEVTVLLEHQKKVSKT-----RHTRETVLRRAKRRWAPIPCSMQENSL 149
Query: 153 QPFPRDVGKVVDSDRPERSK--FRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV 210
PFP + +V +SD + + ++G+GVD+EP +F I +TG++ TR +DRE V
Sbjct: 150 GPFPLFLQQV-ESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDV 208
Query: 211 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF 270
+ L + +G + + P+PL + V D+NDN P+F E Y V+E S GTTV + A
Sbjct: 209 FDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCAT 268
Query: 271 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI 330
D D+P T + L+Y+I QQTP SP +F + P G I TV LDRE ++ KY LI
Sbjct: 269 DRDEPDTMHTRLKYSILQQTPR--SPGLFSVHPSTGVITTVSH--YLDREVVD--KYSLI 322
Query: 331 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVEDKD 389
++ QDM G GL GT+T I + D ND++P F + ++A VEE A V I+ + +EDKD
Sbjct: 323 MKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKD 382
Query: 390 DPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDP 449
T WR +TI+ GN F+I T+ +TNEG+LSVVKPL+YE + L I V NE P
Sbjct: 383 LINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAP 442
Query: 450 LVPDVSYGPS-STATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQ 508
D+ + + A V + V D++EGP P V +E+L+VGS + A DP++
Sbjct: 443 FARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRN 502
Query: 509 HQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGT 568
+RY DP GW+ I+ I+G++ T+ +LDRE N +Y LAID + TGT
Sbjct: 503 GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGT 562
Query: 569 GTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVP 628
L + +EDVNDN P I +C + ++ D+ +H PF F + +
Sbjct: 563 --LAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGA--PFYFSLPNTSPE 618
Query: 629 -DKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
++W ++K+N+T A +S +N Y +PI V D T + LRV +C C
Sbjct: 619 ISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKL--LRVNLCEC 671
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 342 bits (876), Expect = 9e-94
Identities = 224/655 (34%), Positives = 346/655 (52%), Gaps = 30/655 (4%)
Query: 38 INQPAEFIEDQSILNLTFSDC-KGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGK---- 92
+N P++ D+ I + +C + D +R S P F+V +DG + R + K
Sbjct: 37 LNVPSKLEADKIIGRVNLEECFRSADLIRS--SDPDFRVLNDGSVYTARAVALSDKKRSF 94
Query: 93 TLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQR 152
T+++ + + +++ K + + + R + + R KR P + EN
Sbjct: 95 TIWLSDKRKQTQKEVTVLLEHQKKVSKT-----RHTRETVLRRAKRRWAPIPCSMQENSL 149
Query: 153 QPFPRDVGKVVDSDRPERSK--FRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV 210
PFP + +V +SD + + ++G+GVD+EP +F I +TG++ TR +DRE V
Sbjct: 150 GPFPLFLQQV-ESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDV 208
Query: 211 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF 270
+ L + +G + + P+PL + V D+NDN P+F E Y V+E S GTTV + A
Sbjct: 209 FDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCAT 268
Query: 271 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI 330
D D+P T + L+Y+I QQTP SP +F + P G I TV LDRE ++ KY LI
Sbjct: 269 DRDEPDTMHTRLKYSILQQTPR--SPGLFSVHPSTGVITTVSH--YLDREVVD--KYSLI 322
Query: 331 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVEDKD 389
++ QDM G GL GT+T I + D ND++P F + ++A VEE A V I+ + +EDKD
Sbjct: 323 MKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKD 382
Query: 390 DPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDP 449
T WR +TI+ GN F+I T+ +TNEG+LSVVKPL+YE + L I V NE P
Sbjct: 383 LINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAP 442
Query: 450 LVPDVSYGPS-STATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQ 508
D+ + + A V + V D++EGP P V +E+L+VGS + A DP++
Sbjct: 443 FARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRN 502
Query: 509 HQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGT 568
+RY DP GW+ I+ I+G++ T+ +LDRE N +Y LAID + TGT
Sbjct: 503 GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGT 562
Query: 569 GTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVP 628
L + +EDVNDN P I +C + ++ D+ +H PF F + +
Sbjct: 563 --LAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGA--PFYFSLPNTSPE 618
Query: 629 -DKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
++W ++K+N+T A +S +N Y +PI V D T + LRV +C C
Sbjct: 619 ISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKL--LRVNLCEC 671
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 330 bits (847), Expect = 2e-90
Identities = 229/674 (33%), Positives = 343/674 (50%), Gaps = 20/674 (2%)
Query: 13 LSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPY 72
L ++LLLT A + + + H+ P++ ++ + + +C L + S P
Sbjct: 14 LCRLLLLTLAILIFASDACKNVTLHV--PSKLDAEKLVGRVNLKECFTAANLIHS-SDPD 70
Query: 73 FKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSP 132
F++ DG + I + + E+ + I + Q + + +
Sbjct: 71 FQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKK-RHTKEKV 129
Query: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRIN 191
+ R KR P + EN PFP + +V D+ + + + G GVDQEP+ +F +
Sbjct: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVE 189
Query: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
+TG++ TR +DRE +++ T +G T E P+PL + + D+NDN PIF E Y
Sbjct: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYT 249
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
+ E GTTV ++ A D D+P T + L+Y+I Q P PSP +F + P G I T
Sbjct: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMHPTTGVITTT 307
Query: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371
S LDRE ++ KY+L I+ QDM G GL T+T I IDD NDH P FT+ + +
Sbjct: 308 SSQ--LDRELID--KYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTS 363
Query: 372 VEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
VEE V V I+ +TVEDKD T WRA YTI+ GN +F+I T+ +TNEG+L VVKPL
Sbjct: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 431 DYEISAFHTLLIKVENEDPLVPDVS-YGPSSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
+YE L I V NE P + S STATV + V D +EGP P V +E+
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 490 LSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNS 549
VG+ A DP++ IRY DP GW+ I+ G++ LDRE+ + N
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNG 543
Query: 550 VYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDK 609
+Y LA D G T TGTL I L+DVNDN+PFI +C + + ++ D+
Sbjct: 544 IYNITVLASDQGG--RTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
Query: 610 DLHPNTDPFKFEIHKQ-AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPP 668
+H PF F + + ++W++ IN+T A +S + +Y +PI V D +
Sbjct: 602 PIH--GPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRD--RLG 657
Query: 669 MTNITDLRVQVCSC 682
M+++T L V +C C
Sbjct: 658 MSSVTSLDVTLCDC 671
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 330 bits (847), Expect = 2e-90
Identities = 229/674 (33%), Positives = 343/674 (50%), Gaps = 20/674 (2%)
Query: 13 LSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPY 72
L ++LLLT A + + + H+ P++ ++ + + +C L + S P
Sbjct: 14 LCRLLLLTLAILIFASDACKNVTLHV--PSKLDAEKLVGRVNLKECFTAANLIHS-SDPD 70
Query: 73 FKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSP 132
F++ DG + I + + E+ + I + Q + + +
Sbjct: 71 FQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKK-RHTKEKV 129
Query: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRIN 191
+ R KR P + EN PFP + +V D+ + + + G GVDQEP+ +F +
Sbjct: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVE 189
Query: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
+TG++ TR +DRE +++ T +G T E P+PL + + D+NDN PIF E Y
Sbjct: 190 RDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYT 249
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
+ E GTTV ++ A D D+P T + L+Y+I Q P PSP +F + P G I T
Sbjct: 250 FTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVP--PSPTLFSMHPTTGVITTT 307
Query: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371
S LDRE ++ KY+L I+ QDM G GL T+T I IDD NDH P FT+ + +
Sbjct: 308 SSQ--LDRELID--KYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTS 363
Query: 372 VEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
VEE V V I+ +TVEDKD T WRA YTI+ GN +F+I T+ +TNEG+L VVKPL
Sbjct: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 431 DYEISAFHTLLIKVENEDPLVPDVS-YGPSSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
+YE L I V NE P + S STATV + V D +EGP P V +E+
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 490 LSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNS 549
VG+ A DP++ IRY DP GW+ I+ G++ LDRE+ + N
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNG 543
Query: 550 VYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDK 609
+Y LA D G T TGTL I L+DVNDN+PFI +C + + ++ D+
Sbjct: 544 IYNITVLASDQGG--RTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDE 601
Query: 610 DLHPNTDPFKFEIHKQ-AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPP 668
+H PF F + + ++W++ IN+T A +S + +Y +PI V D +
Sbjct: 602 PIH--GPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRD--RLG 657
Query: 669 MTNITDLRVQVCSC 682
M+++T L V +C C
Sbjct: 658 MSSVTSLDVTLCDC 671
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 307 bits (786), Expect = 3e-83
Identities = 212/657 (32%), Positives = 337/657 (51%), Gaps = 27/657 (4%)
Query: 33 QKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNI--TAV 90
QKV+ + P+ + + + +C + L S P F++ DG + ++ ++
Sbjct: 31 QKVY-LRVPSHLQAETLVGKVNLEECLKSASL-IRSSDPAFRILEDGSIYTTHDLILSSE 88
Query: 91 GKTLFVHARTPHAEDMAEL-VIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPE 149
K+ + + E+ V++ ++ + + + + + + R KR P + E
Sbjct: 89 RKSFSIFLSDGQRREQQEIKVVLSARENKSPKK---RHTKDTALKRSKRRWAPIPASLME 145
Query: 150 NQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVI 208
N PFP+ V ++ D+ + + ++G GVD+EP +F I ++TG + TR++DRE
Sbjct: 146 NSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKY 205
Query: 209 AVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMT 268
+ L+ T +G E P+PL + + D NDN P F I V E +GT+V ++T
Sbjct: 206 EQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVT 265
Query: 269 AFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYE 328
A D D+P T + L+Y I QQ PD P F I P+ G ++T +P LDRE + Y+
Sbjct: 266 ATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTG-VITTTTP-FLDREKCDT--YQ 319
Query: 329 LIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVED 387
LI+E +DM G GL T T TI ++D+ND+ P FT+ + VEE + V I+ + V+D
Sbjct: 320 LIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQD 379
Query: 388 KDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENE 447
+D P T +A Y I+ GN +F I T+P TNEG+L VVKPL+YE++ L + V NE
Sbjct: 380 QDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINE 439
Query: 448 DPLVPDVSYGPSS--TATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPD 505
S + T TV + ++D +EGP +P ++ Q+ G LL A DP+
Sbjct: 440 AQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE 499
Query: 506 SLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPA 565
+ +RY D W IN G + T VLDRES FV N+ Y +A+D+
Sbjct: 500 ISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSC 559
Query: 566 TGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQ 625
TGT L++ L+D ND+AP I V +C + ++ +V L D D N PF+F +
Sbjct: 560 TGT--LVVHLDDYNDHAPQIDKEVT-ICQNNEDFAV--LKPVDPDGPENGPPFQFFLDNS 614
Query: 626 AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
A K W I + + A++ QNL+ Y++PI + D T++ L V+VC C
Sbjct: 615 A--SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHM--LTVRVCDC 667
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 307 bits (786), Expect = 3e-83
Identities = 212/657 (32%), Positives = 337/657 (51%), Gaps = 27/657 (4%)
Query: 33 QKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNI--TAV 90
QKV+ + P+ + + + +C + L S P F++ DG + ++ ++
Sbjct: 31 QKVY-LRVPSHLQAETLVGKVNLEECLKSASL-IRSSDPAFRILEDGSIYTTHDLILSSE 88
Query: 91 GKTLFVHARTPHAEDMAEL-VIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPE 149
K+ + + E+ V++ ++ + + + + + + R KR P + E
Sbjct: 89 RKSFSIFLSDGQRREQQEIKVVLSARENKSPKK---RHTKDTALKRSKRRWAPIPASLME 145
Query: 150 NQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVI 208
N PFP+ V ++ D+ + + ++G GVD+EP +F I ++TG + TR++DRE
Sbjct: 146 NSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKY 205
Query: 209 AVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMT 268
+ L+ T +G E P+PL + + D NDN P F I V E +GT+V ++T
Sbjct: 206 EQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVT 265
Query: 269 AFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYE 328
A D D+P T + L+Y I QQ PD P F I P+ G ++T +P LDRE + Y+
Sbjct: 266 ATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTG-VITTTTP-FLDREKCDT--YQ 319
Query: 329 LIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVED 387
LI+E +DM G GL T T TI ++D+ND+ P FT+ + VEE + V I+ + V+D
Sbjct: 320 LIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQD 379
Query: 388 KDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENE 447
+D P T +A Y I+ GN +F I T+P TNEG+L VVKPL+YE++ L + V NE
Sbjct: 380 QDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINE 439
Query: 448 DPLVPDVSYGPSS--TATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPD 505
S + T TV + ++D +EGP +P ++ Q+ G LL A DP+
Sbjct: 440 AQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE 499
Query: 506 SLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPA 565
+ +RY D W IN G + T VLDRES FV N+ Y +A+D+
Sbjct: 500 ISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSC 559
Query: 566 TGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQ 625
TGT L++ L+D ND+AP I V +C + ++ +V L D D N PF+F +
Sbjct: 560 TGT--LVVHLDDYNDHAPQIDKEVT-ICQNNEDFAV--LKPVDPDGPENGPPFQFFLDNS 614
Query: 626 AVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
A K W I + + A++ QNL+ Y++PI + D T++ L V+VC C
Sbjct: 615 A--SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHM--LTVRVCDC 667
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 304 bits (778), Expect = 2e-82
Identities = 188/565 (33%), Positives = 308/565 (54%), Gaps = 29/565 (5%)
Query: 132 PVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERS-KFRLTGKGVDQEPK-GIFR 189
P+ R KR V++ + + E PFP+ +G++ ++ S + ++G GVD+ P+ G+F
Sbjct: 48 PLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFS 107
Query: 190 INEN-TGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFRE 247
+ ++ G + V R +DRE+ + ++ + + + GK ++ + + + D ND+ P F E
Sbjct: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
Query: 248 GPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGD 307
+ V E G + +M A D D+ T N+ + Y + QTP F +D G+
Sbjct: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLSGE 226
Query: 308 IVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKE 367
I LD ET P++ L+I A+D + L+ T T + + + N+H P FT++
Sbjct: 227 IRL---SGCLDYETA--PQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQEN 279
Query: 368 FQATVEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSV 426
++ + EG ++ L V+D+D P T AWRA + I++GN F+I T+P+TNEG+L+V
Sbjct: 280 YKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNV 339
Query: 427 VKPLDYEISAFHTLLIKVENEDPLV------PDVSYGPSSTATVHITVLDVNEGPVFYPD 480
+KPLDYE +L+I VENE+ LV +++ATV + V D N+ P F+P
Sbjct: 340 IKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQ 399
Query: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
+V ++E G++L T NA DPDS IRY + DPA W++++ +G V T +D
Sbjct: 400 SFIVNKEEGARPGTLLGTFNAMDPDS----QIRYELVHDPANWVSVDKNSGVVITVEPID 455
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPT--VAEVCDDAKN 598
RESP V+NS Y + A+D G PP T TGTL++ L D+NDN P + P EVC+ A +
Sbjct: 456 RESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVH 515
Query: 599 LSVVILGASDKDLHPNTDPFKFEIHKQ-AVPDKVWKISKINNTHALVSLLQNLNKANYNL 657
+ I A D DL P +DPF FE+ + WK+ + + L++L + NY +
Sbjct: 516 EPLHI-EAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLV 574
Query: 658 PIMVTDSGKPPMTNITDLRVQVCSC 682
P+ + D K ++ + V++C C
Sbjct: 575 PLFIGD--KQGLSQKQTVHVRICPC 597
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 278 bits (712), Expect = 1e-74
Identities = 183/577 (31%), Positives = 291/577 (50%), Gaps = 34/577 (5%)
Query: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRIN 191
V RQKR + E + + K+ D + ++ +R++G G+D+ P G+F IN
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG +++T +DRE+ ++ ++ + G+ LE P+ L V V+D NDN P+F + Y
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
+ E S T V+++ A DAD+ N+ + Y I Q P MF ++ G++ T+
Sbjct: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPS--GAPMFILNRYTGEVCTM 221
Query: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371
S LDRE ++ Y L++ D G GL+ I + D ND+ P K + A+
Sbjct: 222 SS--FLDRE--QHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSAS 277
Query: 372 VEEGAV-GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
+EE + ++ L D D+ T W A Y I++GN G F+I T+PQTNEG+L VVK L
Sbjct: 278 IEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKML 337
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVH-----ITVLDVNEGPVFYPDPMMVT 485
DYE + L I V+N+ D Y +S +H I V+DV EGP F+P M +
Sbjct: 338 DYEQAPNIQLSIGVKNQ----ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFS 393
Query: 486 RQEDLSVGS----VLLTVNATDPDSLQHQT-IRYSVYKDPAGWLNINPINGTVDTTAVLD 540
+E + S VL T A D D+ T +RY + D WL I+ G + + D
Sbjct: 394 VREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFD 453
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS 600
++S ++ N +YTA LAID G+ T TGT+ I + D+ND P I+P +C D+ ++
Sbjct: 454 KKSKYIINGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVL 512
Query: 601 VVILGASDKDLHPNTDPFKFEI--HKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLP 658
+ + + H PF F + + D +W + N T A+++ Q L+ Y +P
Sbjct: 513 ISV------NEHSYGSPFTFCVVDEPPGIAD-MWDVRSTNATSAILTAKQVLSPGFYEIP 565
Query: 659 IMVTDSGKPPMTNITDLRVQVCSCRNSK--VDCNAAG 693
I+V DS +++ C C ++ +D AAG
Sbjct: 566 ILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAG 602
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 278 bits (712), Expect = 1e-74
Identities = 183/577 (31%), Positives = 291/577 (50%), Gaps = 34/577 (5%)
Query: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRIN 191
V RQKR + E + + K+ D + ++ +R++G G+D+ P G+F IN
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG +++T +DRE+ ++ ++ + G+ LE P+ L V V+D NDN P+F + Y
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
+ E S T V+++ A DAD+ N+ + Y I Q P MF ++ G++ T+
Sbjct: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPS--GAPMFILNRYTGEVCTM 221
Query: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371
S LDRE ++ Y L++ D G GL+ I + D ND+ P K + A+
Sbjct: 222 SS--FLDRE--QHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSAS 277
Query: 372 VEEGAV-GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
+EE + ++ L D D+ T W A Y I++GN G F+I T+PQTNEG+L VVK L
Sbjct: 278 IEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKML 337
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVH-----ITVLDVNEGPVFYPDPMMVT 485
DYE + L I V+N+ D Y +S +H I V+DV EGP F+P M +
Sbjct: 338 DYEQAPNIQLSIGVKNQ----ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFS 393
Query: 486 RQEDLSVGS----VLLTVNATDPDSLQHQT-IRYSVYKDPAGWLNINPINGTVDTTAVLD 540
+E + S VL T A D D+ T +RY + D WL I+ G + + D
Sbjct: 394 VREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFD 453
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS 600
++S ++ N +YTA LAID G+ T TGT+ I + D+ND P I+P +C D+ ++
Sbjct: 454 KKSKYIINGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVL 512
Query: 601 VVILGASDKDLHPNTDPFKFEI--HKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLP 658
+ + + H PF F + + D +W + N T A+++ Q L+ Y +P
Sbjct: 513 ISV------NEHSYGSPFTFCVVDEPPGIAD-MWDVRSTNATSAILTAKQVLSPGFYEIP 565
Query: 659 IMVTDSGKPPMTNITDLRVQVCSCRNSK--VDCNAAG 693
I+V DS +++ C C ++ +D AAG
Sbjct: 566 ILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAG 602
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 267 bits (682), Expect = 3e-71
Identities = 202/595 (33%), Positives = 309/595 (51%), Gaps = 37/595 (6%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KRS V + + E P VGK+ D D+ + S K+ L+G+G IF I+E
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IFIIDE 99
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
NTG + T+ LDRE A Y L + D + K +E + + D NDN P F +GPY
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
V E SP GT+V+++TA DADDP N A + Y+I Q P F ++P+ G I T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE + +Y L+I+A+DM G + GL+GT + T+ + D ND+ P+F ++ +Q
Sbjct: 214 ALPN--MDREAKD--QYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQY 269
Query: 371 TVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
V E V ++ D Y I++G+ F+I + +T EG++++ K L
Sbjct: 270 NVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKEL 329
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
D+E +TL I+ N+D +S GP S T TV I V DV+E PVF + E
Sbjct: 330 DFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEA 389
Query: 490 LSVGSVLLTVNATDPDSLQHQTIRYSVYK--DPAGWLNINPINGTVDTTAVLDRESPFVD 547
VG+++ TV A DPDS + +RYS+ + D + NI+ +G + T LDRE+
Sbjct: 390 TQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET---- 444
Query: 548 NSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVCDDAKNLSVV-ILG 605
N+++ LA++S NP G G + IT+ D+NDNAP F VC++A+ V+ +
Sbjct: 445 NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKIS 504
Query: 606 ASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQN----LNKANYNLPIMV 661
A DKD N F F + A + + + + A + +N ++ Y LPI +
Sbjct: 505 AVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 662 TDSGKPPMTNITDLRVQVCSCRNSKV--DCNA-AGALRFSLPSVLLLSLFSLACL 713
DSG P +++ L ++VC C V CNA A L L + L+++ LAC+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAI--LACV 617
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 267 bits (682), Expect = 3e-71
Identities = 202/595 (33%), Positives = 309/595 (51%), Gaps = 37/595 (6%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KRS V + + E P VGK+ D D+ + S K+ L+G+G IF I+E
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IFIIDE 99
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
NTG + T+ LDRE A Y L + D + K +E + + D NDN P F +GPY
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
V E SP GT+V+++TA DADDP N A + Y+I Q P F ++P+ G I T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE + +Y L+I+A+DM G + GL+GT + T+ + D ND+ P+F ++ +Q
Sbjct: 214 ALPN--MDREAKD--QYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQY 269
Query: 371 TVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
V E V ++ D Y I++G+ F+I + +T EG++++ K L
Sbjct: 270 NVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKEL 329
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
D+E +TL I+ N+D +S GP S T TV I V DV+E PVF + E
Sbjct: 330 DFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEA 389
Query: 490 LSVGSVLLTVNATDPDSLQHQTIRYSVYK--DPAGWLNINPINGTVDTTAVLDRESPFVD 547
VG+++ TV A DPDS + +RYS+ + D + NI+ +G + T LDRE+
Sbjct: 390 TQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET---- 444
Query: 548 NSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVCDDAKNLSVV-ILG 605
N+++ LA++S NP G G + IT+ D+NDNAP F VC++A+ V+ +
Sbjct: 445 NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKIS 504
Query: 606 ASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQN----LNKANYNLPIMV 661
A DKD N F F + A + + + + A + +N ++ Y LPI +
Sbjct: 505 AVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 662 TDSGKPPMTNITDLRVQVCSCRNSKV--DCNA-AGALRFSLPSVLLLSLFSLACL 713
DSG P +++ L ++VC C V CNA A L L + L+++ LAC+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAI--LACV 617
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 256 bits (653), Expect = 7e-68
Identities = 193/594 (32%), Positives = 309/594 (52%), Gaps = 39/594 (6%)
Query: 105 DMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKV-V 163
D+ V+ QG L+ + S R KRS V + + E P VGK+
Sbjct: 27 DLTTTVLSDTPTPQGELEALLSDKPQSH-QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHS 85
Query: 164 DSDRPERS-KFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVN- 221
D DR + S K+ L+G+G +F I++ TG + + LDRE A Y L + D
Sbjct: 86 DMDRGDGSIKYILSGEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRT 141
Query: 222 GKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDN-A 280
G+ +E + + D NDN P F +GPY+ V E SP GT+V+++TA DADDP N A
Sbjct: 142 GRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSA 201
Query: 281 LLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLD 340
+ Y+I Q P F +D + G V+ AL++ + YE+II+A+DM G
Sbjct: 202 RVVYSILQGQP------YFSVDSKTG----VIRTALMNMDREAKEYYEVIIQAKDMGGQL 251
Query: 341 VGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGA--VGVIVNLTVEDKDDPTTGAWRA 398
GL GT T I + D ND+ P+F +K +Q +V E A + + +D D+ +
Sbjct: 252 GGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMK- 310
Query: 399 AYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP 458
YTI++G+ +F+I T+P G+++V KPL +E +TL ++ N + ++ GP
Sbjct: 311 -YTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGP 369
Query: 459 -SSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY 517
T TVHI+V DV+E PVF P V ED+++G+ + ++A DPD + + +IRYS+
Sbjct: 370 FQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPD-VTNNSIRYSID 428
Query: 518 K--DPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITL 575
+ DP + ++ G + T LDRE + S + LA++ NP G+ + I +
Sbjct: 429 RSSDPGRFFYVDITTGALMTARPLDRE----EFSWHNITVLAMEMNNPSQVGSVPVTIKV 484
Query: 576 EDVNDNAPFIYPTVAE--VCDDAKNLSVV-ILGASDKDLHPNTDPFKFEIHKQAVPDKVW 632
DVNDNAP +P E VC++AK ++ + A D+D N F + + +A + +
Sbjct: 485 LDVNDNAP-EFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNF 543
Query: 633 KISKINNTHALV----SLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
I + A + S + ++ ++LPI++ DSG+P +++ L +QVCSC
Sbjct: 544 TIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSC 597
Score = 103 bits (258), Expect = 4e-22
Identities = 109/408 (26%), Positives = 179/408 (43%), Gaps = 35/408 (8%)
Query: 188 FRINENTGSV-SVTRTLDREVIAVYQLFVETTDVNGKT--LEGPVPLEVIVIDQNDNRPI 244
F ++ TG + + +DRE Y++ ++ D+ G+ L G + + + D NDN P
Sbjct: 214 FSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPR 273
Query: 245 FREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPE 304
F + Y V+E +P +TV R+ A D D+ NA ++Y I D + F I +
Sbjct: 274 FPQKHYQMSVLESAPISSTVGRVFAKDLDEGI--NAEMKYTI----VDGDGADAFDISTD 327
Query: 305 KG---DIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVG-LTGTATATIMIDDKNDHS 360
I+TV P + + K E +M L++G T T I ++D D
Sbjct: 328 PNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEP 386
Query: 361 PKFTKKEFQATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTII-NGNPGQSFEIHTNPQ 418
P F + V E+ A+G + + D T + R Y+I + +PG+ F +
Sbjct: 387 PVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIR--YSIDRSSDPGRFFYV----D 440
Query: 419 TNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHIT--VLDVNEGPV 476
G L +PLD E ++H + + + PS +V +T VLDVN+
Sbjct: 441 ITTGALMTARPLDREEFSWHNITVLAMEMN--------NPSQVGSVPVTIKVLDVNDNAP 492
Query: 477 FYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQH-QTIRYSVYKDPAGWLNINPINGTVDT 535
+P E+ G ++ TV+A D D ++ Q YS+ + A N + +T
Sbjct: 493 EFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNT 552
Query: 536 TAVLDRESPF--VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDN 581
+L R S F + SV+ L DSG P + TGTL I + +D+
Sbjct: 553 ARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 253 bits (646), Expect = 4e-67
Identities = 185/598 (30%), Positives = 286/598 (47%), Gaps = 29/598 (4%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERS---KFRLTGKGVDQEPKGIFRIN 191
RQKR+ + +P+ + E + + K+ ER ++ TGKG+ + P GIF N
Sbjct: 46 RQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFN 105
Query: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
++TG ++VT LDRE + L D G +E P+ L + V+D NDN P+F + ++
Sbjct: 106 KDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFV 165
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311
G V E S T VM++ A DAD+P T N+ + Y I P P +FY++ + G+I T
Sbjct: 166 GSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEP--AYPPVFYLNKDTGEIYT- 222
Query: 312 VSPALLDRETLENPKYELIIEAQDMAG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ LDRE E+ Y L +EA+D G + A I I D ND+ P K +
Sbjct: 223 -TSVTLDRE--EHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEG 279
Query: 371 TVEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKP 429
VEE V V + + V D D+ + W A +T +GN G F I T+ QTNEG+++++K
Sbjct: 280 MVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKE 339
Query: 430 LDYEISAFHTLLIKVENEDPLVPDV--SYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQ 487
+DYE + V N+ + Y P + + + V +V EG F + +
Sbjct: 340 VDYEEMKNLDFSVIVANKAAFHKSIRSKYKP-TPIPIKVKVKNVKEGIHFKSSVISIYVS 398
Query: 488 EDL---SVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESP 544
E + S G ++ A D D+ RY +D W++++ + + + D ES
Sbjct: 399 ESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESR 458
Query: 545 FVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVIL 604
+V N YT +AI P T TGT+LI +ED+NDN P + V +C DA+ ++V
Sbjct: 459 YVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVT-- 516
Query: 605 GASDKDLHPNTDPFKFE-IHKQAVPDKVWKISKINNTHALVSLLQ-NLNKANYNLPIMVT 662
A D D HPN+ PF F I K + WKI++ +T L+ + L ++ I
Sbjct: 517 -AEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDN 575
Query: 663 DSGKPPMTNITDLRVQVC----SCRNSKVDCNAA---GALRFSLPSVLLLSLFSLACL 713
P + L V C CR ++ D A+ + + LLL L L L
Sbjct: 576 QGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLL 633
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 245 bits (625), Expect = 1e-64
Identities = 210/602 (34%), Positives = 314/602 (52%), Gaps = 48/602 (7%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KR V + + E P P+ VGK+ +SD+ + S K+ LTG+G IF I++
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG + T++LDRE Y L + D K LE + V D NDN P F +GPYI
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
V E S GT+V+++TA DADDP N A + Y+I Q P F +DP+ G I T
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE E+ Y ++I+A+DMAG GL+G+ T I + D ND+ P+F +K +Q
Sbjct: 220 ALHN--MDREAREH--YSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQL 275
Query: 371 TVEEGA-VGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKP 429
V E A VG V ++ D T Y+IING+ F I T+ +T EG+LS+ KP
Sbjct: 276 YVPESAQVGSAVG-KIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKP 334
Query: 430 LDYEISAFHTLLIKVENEDPLVPDVSYGPSSTAT-VHITVLDVNEGPVFYPDPMMVTRQE 488
L+YE +TL I+ N GP AT + I V DV+E P+F ++ E
Sbjct: 335 LNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYE 394
Query: 489 DLSVGSVLLTVNATDPD---SLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPF 545
+ +G+V+ TV A DPD SL I Y+V D + NI+ GT+ TT VLDRE
Sbjct: 395 NAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE--- 449
Query: 546 VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFI---YPTVAEVCDDAKNLSVV 602
+ Y A + NP T+ I + DVNDN P + Y + VC+++K V+
Sbjct: 450 -ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDII--VCENSKPGQVI 506
Query: 603 -ILGASDKDLHPNTDPFKFEIHKQAVPDKVWKI-SKINNTHALVSLLQNLNKA---NYNL 657
+ A+DKD N F F + ++ + + + +NT ++++ + ++ Y L
Sbjct: 507 HTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYL 566
Query: 658 PIMVTDSGKPPMTNITDLRVQVCSC-RNSKV-DCNA------AGALRFSLPSVLLLSLFS 709
PIM++D G P +++ + L ++VC+C R+ +V C+A AG +L ++LL L
Sbjct: 567 PIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLIL 626
Query: 710 LA 711
LA
Sbjct: 627 LA 628
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 238 bits (606), Expect = 2e-62
Identities = 188/626 (30%), Positives = 289/626 (46%), Gaps = 52/626 (8%)
Query: 72 YFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTS 131
YF++N+ G ++L T G A+ P +++ KD+ G ++ F+ T+
Sbjct: 179 YFQINNKTGAISL---TREGSQELNPAKNPSYN-----LVISVKDMGGQSEN--SFSDTT 228
Query: 132 PVPRQKRSIVVS--------PILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQE 183
V I+V+ P+ + EN P P + +V +D +++ L K ++
Sbjct: 229 SV-----DIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWND--PGAQYSLVDK--EKL 279
Query: 184 PKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRP 243
P+ F I++ G + VT+ LDRE Y + D GK L P+ + V V D NDN P
Sbjct: 280 PRFPFSIDQE-GDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPP 338
Query: 244 IFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDP 303
+ V E G ++ +TA D D+ T N+ L Y I +QTP P +F I
Sbjct: 339 TCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQT 398
Query: 304 EKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKF 363
G ++ + +L ++T P+Y L IE D I + D ND P F
Sbjct: 399 YAG-MLQLAKQSLKKQDT---PQYNLTIEVSDK-----DFKTLCFVQINVIDINDQIPIF 449
Query: 364 TKKEFQ--ATVEEGAVG-VIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN 420
K ++ E+ +G I+ + D D+P TG+ + Y II G+ + T+P TN
Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTN 509
Query: 421 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD 480
G + + KPLD+E +A ++ K EN +PLV V Y SS A + V DVNE P F
Sbjct: 510 TGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQFSQH 569
Query: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
ED+++G+ + V A DP+ L I YS+ D GWL I+ + G + + A LD
Sbjct: 570 VFQAKVSEDVAIGTKVGNVTAKDPEGLD---ISYSLRGDTRGWLKIDHVTGEIFSVAPLD 626
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYP--TVAEVCDDAKN 598
RE+ S Y +A + G + + L DVNDN P + T C
Sbjct: 627 REA----GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSA 682
Query: 599 LSVVILGASDKDLHPNTDP-FKFEIHKQAVPDKVWKISKINNTHALVSLLQ-NLNKANYN 656
+I A+D D H P F F + ++ + W++SKIN THA +S + Y
Sbjct: 683 PGSLIFEATDDDQHLFRGPHFTFSLGSGSLQND-WEVSKINGTHARLSTRHTEFEEREYV 741
Query: 657 LPIMVTDSGKPPMTNITDLRVQVCSC 682
+ I + D G+PP+ I L V CSC
Sbjct: 742 VLIRINDGGRPPLEGIVSLPVTFCSC 767
Score = 116 bits (290), Expect = 8e-26
Identities = 101/342 (29%), Positives = 152/342 (44%), Gaps = 32/342 (9%)
Query: 168 PERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEG 227
P F LTG E IF I E G + R LDRE + + L V D NG +EG
Sbjct: 55 PPAVTFELTG-----ETDNIFVI-EREGLLYYNRALDRETRSTHNLQVAALDANGIIVEG 108
Query: 228 PVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIR 287
PVP+ + V D NDNRP F + Y G V + S G + + A D DDPAT N L Y I
Sbjct: 109 PVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIV 168
Query: 288 QQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG-LDVGLTGT 346
Q P + F I+ + G +++ + +NP Y L+I +DM G + + T
Sbjct: 169 IQLPMINNVMYFQINNKTG-AISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDT 227
Query: 347 ATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGN 406
+ I++ + +PK + VE + +T +DP A Y++++
Sbjct: 228 TSVDIIVTENIWKAPKPVE-----MVENSTDPHPIKITQVRWNDP-----GAQYSLVDKE 277
Query: 407 PGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP--SSTATV 464
F + EG + V +PLD E + ++E YG S +
Sbjct: 278 KLPRFPFSID---QEGDIYVTQPLDREEKDAYVFYAVAKDE--------YGKPLSYPLEI 326
Query: 465 HITVLDVNEGPVFYPDPMMVTR-QEDLSVGSVLLTVNATDPD 505
H+ V D+N+ P P P+ V QE+ +G+ + T+ A D D
Sbjct: 327 HVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRD 368
Score = 30.0 bits (66), Expect = 7.8
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)
Query: 529 INGTVDTTAVLDRESPFVDN--------SVYTALFLAIDSGNPPATGTGTLLITLEDVND 580
+ G D V++RE N S + A+D+ G + I ++D+ND
Sbjct: 62 LTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDIND 121
Query: 581 NAPFIYPTVAEVC---DDAKNLSVVILGASDKD--LHPNTDPFKFEIHKQAVPDKVWKIS 635
N P + E + + + A+D D PN + ++I Q
Sbjct: 122 NRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLY-YQIVIQLPMINNVMYF 180
Query: 636 KINNTHALVSLL----QNLNKA---NYNLPIMVTDSGKPPMTNITD 674
+INN +SL Q LN A +YNL I V D G + +D
Sbjct: 181 QINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSD 226
>gi|221316593 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 238 bits (606), Expect = 2e-62
Identities = 188/626 (30%), Positives = 289/626 (46%), Gaps = 52/626 (8%)
Query: 72 YFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTS 131
YF++N+ G ++L T G A+ P +++ KD+ G ++ F+ T+
Sbjct: 179 YFQINNKTGAISL---TREGSQELNPAKNPSYN-----LVISVKDMGGQSEN--SFSDTT 228
Query: 132 PVPRQKRSIVVS--------PILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQE 183
V I+V+ P+ + EN P P + +V +D +++ L K ++
Sbjct: 229 SV-----DIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWND--PGAQYSLVDK--EKL 279
Query: 184 PKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRP 243
P+ F I++ G + VT+ LDRE Y + D GK L P+ + V V D NDN P
Sbjct: 280 PRFPFSIDQE-GDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPP 338
Query: 244 IFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDP 303
+ V E G ++ +TA D D+ T N+ L Y I +QTP P +F I
Sbjct: 339 TCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQT 398
Query: 304 EKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKF 363
G ++ + +L ++T P+Y L IE D I + D ND P F
Sbjct: 399 YAG-MLQLAKQSLKKQDT---PQYNLTIEVSDK-----DFKTLCFVQINVIDINDQIPIF 449
Query: 364 TKKEFQ--ATVEEGAVG-VIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN 420
K ++ E+ +G I+ + D D+P TG+ + Y II G+ + T+P TN
Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTN 509
Query: 421 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD 480
G + + KPLD+E +A ++ K EN +PLV V Y SS A + V DVNE P F
Sbjct: 510 TGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQFSQH 569
Query: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
ED+++G+ + V A DP+ L I YS+ D GWL I+ + G + + A LD
Sbjct: 570 VFQAKVSEDVAIGTKVGNVTAKDPEGLD---ISYSLRGDTRGWLKIDHVTGEIFSVAPLD 626
Query: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYP--TVAEVCDDAKN 598
RE+ S Y +A + G + + L DVNDN P + T C
Sbjct: 627 REA----GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSA 682
Query: 599 LSVVILGASDKDLHPNTDP-FKFEIHKQAVPDKVWKISKINNTHALVSLLQ-NLNKANYN 656
+I A+D D H P F F + ++ + W++SKIN THA +S + Y
Sbjct: 683 PGSLIFEATDDDQHLFRGPHFTFSLGSGSLQND-WEVSKINGTHARLSTRHTEFEEREYV 741
Query: 657 LPIMVTDSGKPPMTNITDLRVQVCSC 682
+ I + D G+PP+ I L V CSC
Sbjct: 742 VLIRINDGGRPPLEGIVSLPVTFCSC 767
Score = 116 bits (290), Expect = 8e-26
Identities = 101/342 (29%), Positives = 152/342 (44%), Gaps = 32/342 (9%)
Query: 168 PERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEG 227
P F LTG E IF I E G + R LDRE + + L V D NG +EG
Sbjct: 55 PPAVTFELTG-----ETDNIFVI-EREGLLYYNRALDRETRSTHNLQVAALDANGIIVEG 108
Query: 228 PVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIR 287
PVP+ + V D NDNRP F + Y G V + S G + + A D DDPAT N L Y I
Sbjct: 109 PVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIV 168
Query: 288 QQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG-LDVGLTGT 346
Q P + F I+ + G +++ + +NP Y L+I +DM G + + T
Sbjct: 169 IQLPMINNVMYFQINNKTG-AISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDT 227
Query: 347 ATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGN 406
+ I++ + +PK + VE + +T +DP A Y++++
Sbjct: 228 TSVDIIVTENIWKAPKPVE-----MVENSTDPHPIKITQVRWNDP-----GAQYSLVDKE 277
Query: 407 PGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP--SSTATV 464
F + EG + V +PLD E + ++E YG S +
Sbjct: 278 KLPRFPFSID---QEGDIYVTQPLDREEKDAYVFYAVAKDE--------YGKPLSYPLEI 326
Query: 465 HITVLDVNEGPVFYPDPMMVTR-QEDLSVGSVLLTVNATDPD 505
H+ V D+N+ P P P+ V QE+ +G+ + T+ A D D
Sbjct: 327 HVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRD 368
Score = 30.0 bits (66), Expect = 7.8
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)
Query: 529 INGTVDTTAVLDRESPFVDN--------SVYTALFLAIDSGNPPATGTGTLLITLEDVND 580
+ G D V++RE N S + A+D+ G + I ++D+ND
Sbjct: 62 LTGETDNIFVIEREGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDIND 121
Query: 581 NAPFIYPTVAEVC---DDAKNLSVVILGASDKD--LHPNTDPFKFEIHKQAVPDKVWKIS 635
N P + E + + + A+D D PN + ++I Q
Sbjct: 122 NRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLY-YQIVIQLPMINNVMYF 180
Query: 636 KINNTHALVSLL----QNLNKA---NYNLPIMVTDSGKPPMTNITD 674
+INN +SL Q LN A +YNL I V D G + +D
Sbjct: 181 QINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSD 226
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 237 bits (605), Expect = 2e-62
Identities = 197/599 (32%), Positives = 304/599 (50%), Gaps = 41/599 (6%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KR V + + E P P VG++ D D + + K+ L+G+G IF I++
Sbjct: 50 RSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVIDD 105
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
+G++ T+TLDRE A Y L + D + + LE P V V D NDN P F Y
Sbjct: 106 KSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYH 165
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
+V E S GT+V+++TA DADDP N A L Y+I + P F ++ + G I T
Sbjct: 166 ANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGIIRT 219
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE E +Y ++I+A+DM G GL+GT TI + D ND+ PKF + +Q
Sbjct: 220 ALPN--MDREAKE--EYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
Query: 371 TVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
+V E AV V+ KD Y I++G+ +SFEI T+ +T EG++ + KP+
Sbjct: 276 SVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
D+E ++L ++ N +S GP T TV I+V D +E P+F + QE+
Sbjct: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
Query: 490 LSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESPFVD 547
+ G+V+ V+A DPD+ + IRYS+ + D + INP +G + TT LDRE +
Sbjct: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
Query: 548 NSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVC--DDAKNLS---V 601
+ A + N + I + DVNDNAP F P +C D K LS +
Sbjct: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
Query: 602 VILGASDKDLHPNTDPFKFEIHKQAVPDKVWKI-SKINNTHALVSLLQNLNKAN---YNL 657
V + A DKD N F F + + + + + + +NT + + ++ Y L
Sbjct: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
Query: 658 PIMVTDSGKPPMTNITDLRVQVCSC--RNSKVDCNA-AGALRFSLPSVLLLSLFSLACL 713
PI+++D G PPM++ L ++VC C + + CNA A L L + L+++ LAC+
Sbjct: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAI--LACI 627
Score = 68.9 bits (167), Expect = 2e-11
Identities = 120/477 (25%), Positives = 191/477 (40%), Gaps = 62/477 (12%)
Query: 26 DCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCK----GND-KLRYEV--SSPYFKVNSD 78
D P F + +H N P S++ +T SD GN KL Y + PYF V +
Sbjct: 154 DNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQ 213
Query: 79 GGLV--ALRNITAVGKTLFVHARTPHAEDMAELV--IVGGKDIQGSLQDIFKFARTSPVP 134
G++ AL N+ K + H A+DM + + G + +L D+ P
Sbjct: 214 TGIIRTALPNMDREAKEEY-HV-VIQAKDMGGHMGGLSGTTKVTITLTDVND--NPPKFP 269
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINEN- 193
+ + VS +P +VG+V D +T VD + F I +
Sbjct: 270 QSVYQMSVSEAAVP-------GEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDY 322
Query: 194 ---TGSVSVTRTLDREVIAVYQLFVETTDVN---GKTLEGPVPLEVIV---IDQNDNRPI 244
G + + + +D E Y L VE +V+ GP V V ++ D P+
Sbjct: 323 ETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPM 382
Query: 245 FREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPE 304
F YI V E + GT V R+ A DP N+ +RY+I + T F I+PE
Sbjct: 383 FLAPSYIHEVQENAAAGTVVGRV---HAKDPDAANSPIRYSIDRHT---DLDRFFTINPE 436
Query: 305 KGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFT 364
G I T LDRE E + + A ++ I + D ND++PKF
Sbjct: 437 DGFIKTTKP---LDRE--ETAWLNITVFAAEIHNRH--QEAKVPVAIRVLDVNDNAPKFA 489
Query: 365 KKEFQATVEEG------AVGVIVNLTVEDKDDPTTGAWRAAYTI---INGNPGQSFEIHT 415
++ + E + IV ++ +DKDD G R +++ I NP +F +
Sbjct: 490 -APYEGFICESDQTKPLSNQPIVTISADDKDDTANGP-RFIFSLPPEIIHNP--NFTVRD 545
Query: 416 NPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVN 472
N G+ + + + L I + D +P +S ++T T+ + DVN
Sbjct: 546 NRDNTAGVYARRGGFSRQKQDLYLLPIVI--SDGGIPPMS--STNTLTIKVCGCDVN 598
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 237 bits (605), Expect = 2e-62
Identities = 173/560 (30%), Positives = 273/560 (48%), Gaps = 24/560 (4%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVV-DSDRPERSKFRLTGKGVDQEPKGIFRINEN 193
RQKR V E + + K+ D ++ +R++G G+DQ P GIF +++N
Sbjct: 46 RQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKN 105
Query: 194 TGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGH 253
TG +++T +DRE + + + G +E P+ L V ++D NDN P+F + ++G
Sbjct: 106 TGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGE 165
Query: 254 VMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVS 313
+ E S + + VM + A DAD+P N+ + + I Q P MF + G++ T+ +
Sbjct: 166 IEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEP--AGTPMFLLSRNTGEVRTLTN 223
Query: 314 PALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVE 373
LDRE + Y L++ D G GL+ I + D ND+ P F ++ A +E
Sbjct: 224 S--LDRE--QASSYRLVVSGADKDG--EGLSTQCECNIKVKDVNDNFPMFRDSQYSARIE 277
Query: 374 EGAV-GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDY 432
E + ++ V D D+ T W A Y +GN G FEI T+P+TNEG+L VVK LDY
Sbjct: 278 ENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDY 337
Query: 433 EISAFHTLLIKVENEDPLVPDV--SYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDL 490
E L I V+N+ V Y ST V I V++V EG F P T Q+ +
Sbjct: 338 EQLQSVKLSIAVKNKAEFHQSVISRYRVQST-PVTIQVINVREGIAFRPASKTFTVQKGI 396
Query: 491 S----VGSVLLTVNATDPDSLQ-HQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPF 545
S V +L T A D D+ + ++Y + ++ G+L I+ + ++R+S F
Sbjct: 397 SSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTF 456
Query: 546 VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILG 605
+ N TA LAID T TGT+ + + D NDN P VC + SVV+
Sbjct: 457 IVNKTITAEVLAIDE-YTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSP--SVVVSA 513
Query: 606 ASDKDLHPNTDPFKFEIHKQAVP-DKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDS 664
+ + + T P+ F + Q V VW I+ +N T AL+ + + Y++ +++TDS
Sbjct: 514 RTLNNRY--TGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDS 571
Query: 665 GKPPMTNITDLRVQVCSCRN 684
L ++VC C N
Sbjct: 572 QNNRCEMPRSLTLEVCQCDN 591
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 232 bits (592), Expect = 8e-61
Identities = 185/563 (32%), Positives = 272/563 (48%), Gaps = 36/563 (6%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KR V + + E P+ VGK+ D D+ E + K+ L+G G +F I+E
Sbjct: 51 RVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGT----VFTIDE 106
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVNG-KTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG + R+LDRE Y L + D+ K LE + V D NDN P F +GPY+
Sbjct: 107 TTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYV 166
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
V E SP G V+++ A DADDP N A + Y+I Q P F IDP+ G I T
Sbjct: 167 ATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP------YFSIDPKTGVIRT 220
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE E +Y+++I+A+DM G GL GT I + D ND+ P+F K F
Sbjct: 221 ALPN--MDREVKE--QYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHL 276
Query: 371 TVEEGAV--GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVK 428
V E + I + D D Y I+ G+ G F+I T+ T EG++ + K
Sbjct: 277 KVPESSPIGSAIGRIRAVDPDFGQNA--EIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKK 334
Query: 429 PLDYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQ 487
PLD+E +T ++ N S GP TATV I+VLDV+E PVF +
Sbjct: 335 PLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVY 394
Query: 488 EDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESPF 545
ED VG+++ V A D D + +RY + D + I+ GT+ T +LDRES
Sbjct: 395 EDTPVGTIIGAVTAQDLD-VGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES-- 451
Query: 546 VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFI-YPTVAEVCDDAKNLSVV-I 603
+ Y +A NP T +LI + DVN+ P I P VC++AK ++ I
Sbjct: 452 --TAQYNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQI 509
Query: 604 LGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQN----LNKANYNLPI 659
+ A+D+DL P F F + +A + + N A + +N + Y LP+
Sbjct: 510 VSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPV 569
Query: 660 MVTDSGKPPMTNITDLRVQVCSC 682
++ DS P ++ + ++VC C
Sbjct: 570 VIEDSSYPVQSSTNTMTIRVCRC 592
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 231 bits (590), Expect = 1e-60
Identities = 196/607 (32%), Positives = 301/607 (49%), Gaps = 48/607 (7%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
R KR V + + E P VGK+ DSD + + K+ ++G+G IF I+E
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGT----IFLIDE 114
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG + LDRE Y L + D + LE + V D ND+ P F GPYI
Sbjct: 115 LTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI 174
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPAT-DNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
G V E SPTGT+VM++ A DADDP +A L Y++ + F +DP+ G I T
Sbjct: 175 GSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLD------GEHHFTVDPKTGVIRT 228
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
V LDRE+ E +YE++I+A DMAG GL+G+ T TI++ D ND+ P+F +K +Q
Sbjct: 229 AVPD--LDRESQE--RYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQF 284
Query: 371 TVEEGA-VGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVK 428
+++E A +G V + ED D + + G F++ T+ T E ++ V K
Sbjct: 285 SIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQK 344
Query: 429 PLDYEISAFHTLLIKVENE--DPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTR 486
LD+E HT++++ N+ DP D+ A V + V DV+E P F P ++
Sbjct: 345 RLDFESQPVHTVILEALNKFVDPRFADLGTF-RDQAIVRVAVTDVDEPPEFRPPSGLLEV 403
Query: 487 QEDLSVGSVLLTVNATDPDSLQHQTIRYSVYK--DPAGWLNINPINGTVDTTAVLDRESP 544
QED VGS++ V A DPD+ ++ +RY++ + D +I+ G + T LDRE+
Sbjct: 404 QEDAQVGSLVGVVTARDPDA-ANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETA 462
Query: 545 FVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVCDDAKNLSVV- 602
+ LA+++ N +L I + DVNDN P P A VC+DAK ++
Sbjct: 463 ----GWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQ 518
Query: 603 ILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKI-NNTHALVSLLQNLNKAN---YNLP 658
+ D+D F F + +A + + + I +NT A+ + N+ + LP
Sbjct: 519 TISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLP 578
Query: 659 IMVTDSGKPPMTNITDLRVQVCSCRNSKV--DCN----------AAGALRFSLPSVLLLS 706
I+V DSG P +++ L +++C C +S CN + GAL L VL+L
Sbjct: 579 ILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILV 638
Query: 707 LFSLACL 713
+ L L
Sbjct: 639 VLVLLIL 645
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 231 bits (589), Expect = 2e-60
Identities = 199/598 (33%), Positives = 292/598 (48%), Gaps = 43/598 (7%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRP--ERSKFRLTGKGVDQEPKGIFRINE 192
R KR V + + + E P P VG++ P ++ K+ L+G G IF+IN+
Sbjct: 58 RSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGT----IFQIND 113
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
TG + + LDRE A Y L + D K LE P + V D NDN P F GPY
Sbjct: 114 VTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYH 173
Query: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
V E S GT+V +TA DADDP N A L Y+I + P F I+PE I T
Sbjct: 174 ATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP------YFSIEPETAIIKT 227
Query: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
+ +DRE E +Y ++I+A+DM G GL+GT T T+ + D ND+ PKF + +
Sbjct: 228 ALPN--MDREAKE--EYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHF 283
Query: 371 TVEEGAV-GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKP 429
+V E V G + + D A +++Y II+G+ FEI ++ Q +G++ + KP
Sbjct: 284 SVPEDVVLGTAIGRVKANDQDIGENA-QSSYDIIDGDGTALFEITSDAQAQDGIIRLRKP 342
Query: 430 LDYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQE 488
LD+E +TL ++ N GP TATV I V D +E PVF ++ E
Sbjct: 343 LDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHE 402
Query: 489 DLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESPFV 546
+ ++ SV+ V A DPD + IR+S+ + D NIN +G + LDRE
Sbjct: 403 NAALNSVIGQVTARDPD-ITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVW 461
Query: 547 DNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVCDDAKNLSVV-IL 604
N +A + N + I + DVNDNAP F A +C++ K V+ +
Sbjct: 462 HN----ITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTV 517
Query: 605 GASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKAN------YNLP 658
A DKD N F + + + V + + I K N +S+L N N Y LP
Sbjct: 518 SAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKK--NEDNSLSILAKHNGFNRQKQEVYLLP 575
Query: 659 IMVTDSGKPPMTNITDLRVQVCSCRNSKV--DCNA-AGALRFSLPSVLLLSLFSLACL 713
I+++DSG PP+++ + L ++VC C N V CN A L L L+++ LAC+
Sbjct: 576 IIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAI--LACI 631
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 225 bits (573), Expect = 1e-58
Identities = 193/589 (32%), Positives = 294/589 (49%), Gaps = 50/589 (8%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
RQKR + + + E + VGK+ D D+ + S K+ L+G G +F I+E
Sbjct: 51 RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFIIDE 106
Query: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVI---DQNDNRPIFREGP 249
TG + TR +DRE A Y L + +N +TL P VI D NDN P F E
Sbjct: 107 KTGDIHATRRIDREEKAFYTLRAQA--INRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
Query: 250 YIGHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDI 308
Y V E S GT+V+++TA DADDP+ N A + Y+I Q P F ++PE G I
Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
Query: 309 VTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEF 368
T + ++RE E +Y+++I+A+DM G GL+GT T I + D ND+ P+F +
Sbjct: 219 RTALPN--MNRENRE--QYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTI 274
Query: 369 QATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVV 427
V E VG + +V+ D T Y II+G+ F+I T T EG+++V
Sbjct: 275 HLRVLESSPVGTAIG-SVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVK 333
Query: 428 KPLDYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTR 486
KPLDYE +TL ++ EN GP T V I++ DV+E PVF +
Sbjct: 334 KPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEV 393
Query: 487 QEDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESP 544
ED+ VG+++ TV A DPDS+ IR+S+ + D NI+ NG++ T+ LDRE
Sbjct: 394 HEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL- 451
Query: 545 FVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP---FIYPTVAEVCDDAKNLSV 601
+ + +A + NP T + + + DVNDNAP Y T VC++A+ +
Sbjct: 452 ---SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTF--VCENARPGQL 506
Query: 602 V-ILGASDKDLHPNTDPF---KFEIHKQAVPDKVWKISKINNTHALVSLLQNLNK---AN 654
+ + A DKD DP KF AV +NT +++ N+ +
Sbjct: 507 IQTISAVDKD-----DPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEIST 561
Query: 655 YNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVL 703
Y LP++++D+ P ++ L ++VC+C +S+ + + A LP+ L
Sbjct: 562 YLLPVVISDNDYPIQSSTGTLTIRVCAC-DSQGNMQSCSAEALLLPAGL 609
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 225 bits (573), Expect = 1e-58
Identities = 195/577 (33%), Positives = 293/577 (50%), Gaps = 48/577 (8%)
Query: 128 ARTSPVP---RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPE-RSKFRLTGKGVDQ 182
+R P P R +RS V + + E P P +GK+ D DR E R+K+ LTG+G
Sbjct: 31 SREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT 90
Query: 183 EPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDN 241
+F I+E TG++ VT++LDRE A Y L + D + + LE P + V D NDN
Sbjct: 91 ----VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDN 146
Query: 242 RPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFY 300
PIF GPY V E S GT+V+++TA DADDP+ N A L Y + P F
Sbjct: 147 PPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFS 200
Query: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
+DP+ G + T + +DRET E ++ ++I+A+DM G GL+G+ T T+ + D ND+
Sbjct: 201 VDPQTGVVRTAIPN--MDRETQE--EFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNP 256
Query: 361 PKFTKKEFQ-ATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQ 418
PKF + +Q + VE G +V L +D D AY+I++G ++F I T+ Q
Sbjct: 257 PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQ 314
Query: 419 TNEGMLSVVKPLDYEISAFHTLLIKVENE--DPLVPDVSYGP-SSTATVHITVLDVNEGP 475
+G+L+V KPLD+E ++ ++ N DP + GP A+V + V D E P
Sbjct: 315 GRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAY--LRRGPFKDVASVRVAVQDAPEPP 372
Query: 476 VFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTV 533
F +T E+ + G+++ ++A D DS IRYS+ + DP +I P GT+
Sbjct: 373 AFTQAAYHLTVPENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTI 431
Query: 534 DTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEV 592
T A LDRE+ N T L +DS + A+ + TL D NDNAP P V
Sbjct: 432 HTAAPLDREARAWHN--LTVLATELDS-SAQASRVQVAIQTL-DENDNAPQLAEPYDTFV 487
Query: 593 CDDAKNLSVV-ILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLL---- 647
CD A ++ ++ A D+D N+ F+ PD + + +N SLL
Sbjct: 488 CDSAAPGQLIQVIRALDRDEVGNSSHVSFQ--GPLGPDANFTVQ--DNRDGSASLLLPSR 543
Query: 648 -QNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCR 683
A Y +PI + D G+P +++ + V VC C+
Sbjct: 544 PAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQ 580
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 219 bits (559), Expect = 5e-57
Identities = 184/569 (32%), Positives = 287/569 (50%), Gaps = 55/569 (9%)
Query: 135 RQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENT 194
RQKR + + + I E + P VGK+ S + +K+ L G+ V + +FR++ T
Sbjct: 44 RQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNAKYLLKGEYVGK----VFRVDAET 99
Query: 195 GSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFREGPYIGH 253
G V LDRE I+ Y L D + G+ LE P + V D NDN P+F +
Sbjct: 100 GDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNAS 159
Query: 254 VMEGSPTGTTVMRMTAFDADDPAT-DNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVV 312
V E S GT+V+ +TA DADDP D+A + Y I + F ID G I+T+
Sbjct: 160 VPESSAVGTSVISVTAVDADDPTVGDHASVMYQILK------GKEYFAID-NSGRIITIT 212
Query: 313 SPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATV 372
LDRE + +YE+++EA+D GL G +GTAT + + D ND+ P FT+ ++ V
Sbjct: 213 KS--LDRE--KQARYEIVVEARDAQGLR-GDSGTATVLVTLQDINDNFPFFTQTKYTFVV 267
Query: 373 -EEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
E+ VG V +L VED D+P + Y+I+ G+ +F I TNP NEG++ +KPL
Sbjct: 268 PEDTRVGTSVGSLFVEDPDEPQNRMTK--YSILRGDYQDAFTIETNPAHNEGIIKPMKPL 325
Query: 431 DYEISAFHTLLIKVENEDPLVPDVSY---GPSSTATVHITVLDVNEGPVFYPDPMMVTRQ 487
DYE ++ + VE DP + D+ Y + A V I + DV+E P+F P +
Sbjct: 326 DYEYIQQYSFI--VEATDPTI-DLRYMSPPAGNRAQVIINITDVDEPPIF-QQPFYHFQL 381
Query: 488 EDLSVGSVLLTVNATDPDSLQHQTIRYSVYK--DPAGWLNINPINGTVDTTAVLDRESPF 545
++ ++ TV A DPD+ +H +I YS+ + D + + G + LDRE
Sbjct: 382 KENQKKPLIGTVLAMDPDAARH-SIGYSIRRTSDKGQFFRVTK-KGDIYNEKELDRE--- 436
Query: 546 VDNSVYTALFLAIDSGNPPATGTGT-------LLITLEDVNDNAP-FIYPTVAEVCDDAK 597
VY L +++ +TGT T + I + D NDNAP F P +VC++A
Sbjct: 437 ----VYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAV 492
Query: 598 NLSVVI-LGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKAN-- 654
+ +V+ + A DKD+ P FKF ++ + + +NT + ++ +
Sbjct: 493 HGQLVLQISAIDKDITPRNVKFKFILNTE---NNFTLTDNHDNTANITVKYGQFDREHTK 549
Query: 655 -YNLPIMVTDSGKPPMTNITDLRVQVCSC 682
+ LP++++D+G P T + L V VC C
Sbjct: 550 VHFLPVVISDNGMPSRTGTSTLTVAVCKC 578
Score = 89.4 bits (220), Expect = 1e-17
Identities = 104/412 (25%), Positives = 170/412 (41%), Gaps = 32/412 (7%)
Query: 185 KGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNG-KTLEGPVPLEVIVIDQNDNRP 243
K F I+ + +++T++LDRE A Y++ VE D G + G + V + D NDN P
Sbjct: 197 KEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFP 256
Query: 244 IFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDP 303
F + Y V E + GT+V + D D+P N + +Y+I + + F I+
Sbjct: 257 FFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEP--QNRMTKYSILRGDYQ----DAFTIET 310
Query: 304 EKGDIVTVVSPAL-LDRETLENPKYELIIEAQD----MAGLDVGLTGTATATIMIDDKND 358
++ P LD E ++ +Y I+EA D + + A I I D D
Sbjct: 311 NPAHNEGIIKPMKPLDYEYIQ--QYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-D 367
Query: 359 HSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIIN-GNPGQSFEIHTNP 417
P F + + ++E ++ + DP Y+I + GQ F +
Sbjct: 368 EPPIFQQPFYHFQLKENQKKPLIGTVLAM--DPDAARHSIGYSIRRTSDKGQFFRV---- 421
Query: 418 QTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVF 477
T +G + K LD E+ ++ L ++ + D G S VHI VLD N+
Sbjct: 422 -TKKGDIYNEKELDREVYPWYNLTVEAKELDST--GTPTGKESIVQVHIEVLDENDNAPE 478
Query: 478 YPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTA 537
+ P E+ G ++L ++A D D T R +K N + D TA
Sbjct: 479 FAKPYQPKVCENAVHGQLVLQISAIDKDI----TPRNVKFKFILNTENNFTLTDNHDNTA 534
Query: 538 VLDRESPFVDNSVYTALFLAI---DSGNPPATGTGTLLITLEDVNDNAPFIY 586
+ + D FL + D+G P TGT TL + + N+ F +
Sbjct: 535 NITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTF 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,192,447
Number of Sequences: 37866
Number of extensions: 1338781
Number of successful extensions: 6839
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2611
Number of HSP's gapped (non-prelim): 1092
length of query: 713
length of database: 18,247,518
effective HSP length: 109
effective length of query: 604
effective length of database: 14,120,124
effective search space: 8528554896
effective search space used: 8528554896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.