Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4502071

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo
sapiens]
         (191 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo s...   431   e-121
gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo ...   421   e-118
gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo ...   382   e-107
gi|4502073 amelogenin, Y-linked precursor [Homo sapiens]              376   e-105
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               79   2e-15
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    74   6e-14
gi|117938768 GNAS complex locus alex [Homo sapiens]                    62   2e-10
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       60   9e-10
gi|50345997 E1A binding protein p300 [Homo sapiens]                    60   1e-09
gi|19923345 RNA binding motif protein 12 [Homo sapiens]                59   3e-09
gi|23510462 RNA binding motif protein 12 [Homo sapiens]                59   3e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               59   3e-09
gi|195232763 ADAM metallopeptidase domain 29 preproprotein [Homo...    59   3e-09
gi|195232761 ADAM metallopeptidase domain 29 preproprotein [Homo...    59   3e-09
gi|195232759 ADAM metallopeptidase domain 29 preproprotein [Homo...    59   3e-09
gi|73765552 ADAM metallopeptidase domain 29 preproprotein [Homo ...    59   3e-09
gi|153792074 proline rich 12 [Homo sapiens]                            59   3e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    57   7e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    57   7e-09
gi|114431236 zinc finger protein 462 [Homo sapiens]                    55   4e-08
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     55   5e-08
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     55   5e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          54   6e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          54   6e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          54   6e-08
gi|146134388 YLP motif containing 1 [Homo sapiens]                     54   6e-08
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         54   8e-08
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                   53   2e-07
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        53   2e-07
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   2e-07

>gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo
           sapiens]
          Length = 191

 Score =  431 bits (1108), Expect = e-121
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60
           MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW
Sbjct: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60

Query: 61  LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120
           LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP
Sbjct: 61  LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120

Query: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
           PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP
Sbjct: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180

Query: 181 STDKTKREEVD 191
           STDKTKREEVD
Sbjct: 181 STDKTKREEVD 191


>gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo
           sapiens]
          Length = 205

 Score =  421 bits (1083), Expect = e-118
 Identities = 191/205 (93%), Positives = 191/205 (93%), Gaps = 14/205 (6%)

Query: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYE--------------VLTPLKWYQSIR 46
           MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYE              VLTPLKWYQSIR
Sbjct: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYENSHSQAINVDRTALVLTPLKWYQSIR 60

Query: 47  PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ 106
           PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ
Sbjct: 61  PPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQ 120

Query: 107 HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166
           HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP
Sbjct: 121 HSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 180

Query: 167 LPPMLPDLTLEAWPSTDKTKREEVD 191
           LPPMLPDLTLEAWPSTDKTKREEVD
Sbjct: 181 LPPMLPDLTLEAWPSTDKTKREEVD 205


>gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo
           sapiens]
          Length = 175

 Score =  382 bits (982), Expect = e-107
 Identities = 175/191 (91%), Positives = 175/191 (91%), Gaps = 16/191 (8%)

Query: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW 60
           MGTWILFACLLGAAFAMP                VLTPLKWYQSIRPPYPSYGYEPMGGW
Sbjct: 1   MGTWILFACLLGAAFAMP----------------VLTPLKWYQSIRPPYPSYGYEPMGGW 44

Query: 61  LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120
           LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP
Sbjct: 45  LHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 104

Query: 121 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
           PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP
Sbjct: 105 PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 164

Query: 181 STDKTKREEVD 191
           STDKTKREEVD
Sbjct: 165 STDKTKREEVD 175


>gi|4502073 amelogenin, Y-linked precursor [Homo sapiens]
          Length = 192

 Score =  376 bits (966), Expect = e-105
 Identities = 169/192 (88%), Positives = 179/192 (93%), Gaps = 1/192 (0%)

Query: 1   MGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQS-IRPPYPSYGYEPMGG 59
           MGTWILFACL+GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQS IRPPY SYGYEPMGG
Sbjct: 1   MGTWILFACLVGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSMIRPPYSSYGYEPMGG 60

Query: 60  WLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL 119
           WLHHQIIPV+SQQHP THTLQ HHHIPVVPAQQP + QQ +MPVPGQ SMTP QHHQPNL
Sbjct: 61  WLHHQIIPVVSQQHPLTHTLQSHHHIPVVPAQQPRVRQQALMPVPGQQSMTPTQHHQPNL 120

Query: 120 PPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAW 179
           P PAQQP+QPQPVQPQPHQPMQPQPPV PMQPL PQPPLPPMFP++PLPP+LPDL LEAW
Sbjct: 121 PLPAQQPFQPQPVQPQPHQPMQPQPPVQPMQPLLPQPPLPPMFPLRPLPPILPDLHLEAW 180

Query: 180 PSTDKTKREEVD 191
           P+TDKTK+EEVD
Sbjct: 181 PATDKTKQEEVD 192


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 57/163 (34%), Positives = 73/163 (44%), Gaps = 28/163 (17%)

Query: 20  PPHPGHPGYINFSYEVLT--PLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTH 77
           PP P  P  +N S+ V T  PL + Q    P P++  +           PV  ++ P   
Sbjct: 483 PPPPPPPTLLNSSHPVPTQSPLPFTQ----PGPAFNQQGQQ--------PVFPRERPVRP 530

Query: 78  TLQPHHHIPVVPAQQP--------VIPQQPMMPVPGQHSMTPIQHHQPNLP----PPAQQ 125
            LQP   + ++   QP        + P+QP +P PGQ  +    H QPNL     PP   
Sbjct: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPT--HTQPNLQGPLHPPLPP 588

Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168
           P+QPQP QPQ   P Q QPP  P    PPQ   PP  P Q  P
Sbjct: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPP 631



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 40/107 (37%), Positives = 45/107 (42%), Gaps = 13/107 (12%)

Query: 66  IPVLSQQHPPTHT---LQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPP 122
           +P   Q   PTHT   LQ   H P+ P  QP  PQQP           P QH  P+ PP 
Sbjct: 562 LPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQ-PQQPQQ-------QPPPQHQPPHQPPH 613

Query: 123 AQQP-YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168
              P +QP P  P  H P       H    +PP PPL PM   Q  P
Sbjct: 614 QPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPP-PPLMPMSQPQFRP 659



 Score = 50.8 bits (120), Expect = 7e-07
 Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 27/95 (28%)

Query: 83  HHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP----YQPQPVQP---- 134
           H   ++P Q PV+PQ P                 P  PPP QQP    +QPQP+QP    
Sbjct: 304 HRPALLPTQPPVVPQAP----------------PPPPPPPQQQPIRSLFQPQPLQPLLPV 347

Query: 135 -QPHQPMQPQPPVHPMQPLPPQPPL--PPMFPMQP 166
             PH P  PQ    P Q   P+  +  PP+ P QP
Sbjct: 348 QHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQP 382



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 25/145 (17%)

Query: 43  QSIRPPYPSYGYEPMGGWLHHQII-PVLSQQHPPTHTLQPHHHIP-------VVPAQQPV 94
           Q+  PP P    +P+      Q + P+L  QHP   +     H+P       ++    PV
Sbjct: 318 QAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPV 377

Query: 95  IPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP-----HQPMQPQPPVHPM 149
            PQQP        ++    H +  +  P Q P  P P QP+P       P  P+ P H  
Sbjct: 378 TPQQPK-------NIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTP 430

Query: 150 QPLPPQPPLPPMFPMQ-----PLPP 169
            P+P     PP  P+Q     P PP
Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPPPP 455



 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 25/58 (43%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 112 IQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169
           ++ H+P L P  Q P  PQ   P P  P Q QP     QP P QP LP   P  P PP
Sbjct: 301 MKDHRPALLP-TQPPVVPQAPPPPPPPPQQ-QPIRSLFQPQPLQPLLPVQHPHHPSPP 356



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 28/104 (26%), Positives = 38/104 (36%), Gaps = 7/104 (6%)

Query: 63  HQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPP 122
           HQ  P    QHPP H    HHH          +P  P+MP+        +Q  QP     
Sbjct: 619 HQPPPQHPPQHPPQHQHHHHHH-------HLSVPPPPLMPMSQPQFRPHVQTAQPQASSS 671

Query: 123 AQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166
             Q  Q Q ++         + P+  MQP  P+       P+ P
Sbjct: 672 RMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAP 715



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 46/201 (22%)

Query: 18  PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQII---PVLSQQHP 74
           P PP    P    F  + L PL   Q    P P  G          +++   P ++ Q P
Sbjct: 323 PPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQP 382

Query: 75  PTHTLQPHHHIPVV-PAQQPV--IPQQPMMPV-----PG-----QHSMTPIQHH------ 115
               + PH    VV P Q P+  +P QP   V     PG     QH+  P+ +       
Sbjct: 383 KNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPR 442

Query: 116 -----QPNLPPPAQ-----------QPYQPQPVQPQPHQPMQPQPP---VHPMQPLPPQP 156
                Q   PPP Q           +P  P  +  +   P  P PP   ++   P+P Q 
Sbjct: 443 LPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQS 502

Query: 157 PLP-----PMFPMQPLPPMLP 172
           PLP     P F  Q   P+ P
Sbjct: 503 PLPFTQPGPAFNQQGQQPVFP 523



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 15/70 (21%)

Query: 116 QPNLPPPAQQPYQPQP--------VQPQPHQPMQP-QPPVHPMQP----LPPQPPLPPMF 162
           QP + P A  P  P P         QPQP QP+ P Q P HP  P    +PPQ   P M 
Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRM- 370

Query: 163 PMQPLPPMLP 172
            M   PP+ P
Sbjct: 371 -MMTPPPVTP 379



 Score = 36.6 bits (83), Expect = 0.014
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 7/43 (16%)

Query: 137 HQP--MQPQPPVHPMQPLPPQPP-----LPPMFPMQPLPPMLP 172
           H+P  +  QPPV P  P PP PP     +  +F  QPL P+LP
Sbjct: 304 HRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLP 346



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 29/130 (22%), Positives = 46/130 (35%), Gaps = 25/130 (19%)

Query: 64  QIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQ----QPMMPVPGQH------------ 107
           +++  L+QQ    +   P    P    +Q + P      P++P PG              
Sbjct: 822 ELLERLAQQQQQLYAPPP----PAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVK 877

Query: 108 ----SMTPIQHHQPN-LPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMF 162
               S++ +Q    N +P  A   YQ Q ++   H       P    QPL    P+ P  
Sbjct: 878 NQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPAD 937

Query: 163 PMQPLPPMLP 172
             +P  P  P
Sbjct: 938 VEEPAVPQTP 947


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 74.3 bits (181), Expect = 6e-14
 Identities = 56/156 (35%), Positives = 67/156 (42%), Gaps = 28/156 (17%)

Query: 17  MPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPT 76
           +P+PP P  P  +        P+     I P  P     P       ++ PV     PP 
Sbjct: 247 LPVPPMPPRPPMV--------PMPPRPPIAPMPPMAPVPPGS-----RMAPV-----PPG 288

Query: 77  HTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP 136
             + P   +P  P   PV P  PM PVP    M P+    P  PP A+ P  P   +  P
Sbjct: 289 PRMAP---VPPWPPMAPVPPWPPMAPVPTGPPMAPV----PPGPPMARVPPGPPMARVPP 341

Query: 137 HQPMQPQPPVHPMQPLPPQP---PLPPMFPMQPLPP 169
             PM P PP  PM PLPP P   PLPP  PM PLPP
Sbjct: 342 GPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377



 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 44/115 (38%), Positives = 48/115 (41%), Gaps = 8/115 (6%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
           PP   + P   I  +P   PV P   M PVP    M P+    P  P P   P  P P  
Sbjct: 256 PPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTG 315

Query: 134 PQ-----PHQPMQPQPPVHPMQPLPPQPP---LPPMFPMQPLPPMLPDLTLEAWP 180
           P      P  PM   PP  PM  +PP PP   LPP  PM PLPP  P   L   P
Sbjct: 316 PPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGP 370



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 42/130 (32%), Positives = 51/130 (39%), Gaps = 28/130 (21%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQP------------------MMPVPGQHS 108
           P L     P     P   +P +P + P++P  P                  M PVP    
Sbjct: 231 PALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPR 290

Query: 109 MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL------PPMF 162
           M P+    P  P P   P  P P  P    PM P PP  PM  +PP PP+      PPM 
Sbjct: 291 MAPVPPWPPMAPVPPWPPMAPVPTGP----PMAPVPPGPPMARVPPGPPMARVPPGPPMA 346

Query: 163 PMQPLPPMLP 172
           P+ P PPM P
Sbjct: 347 PLPPGPPMAP 356



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 25/91 (27%)

Query: 93  PVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQP- 151
           P +P+ P++PVP               P P + P  P P +P    P+ P PP+ P+ P 
Sbjct: 239 PQLPRPPVLPVP---------------PMPPRPPMVPMPPRP----PIAPMPPMAPVPPG 279

Query: 152 --LPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
             + P PP P M P+ P PPM P   +  WP
Sbjct: 280 SRMAPVPPGPRMAPVPPWPPMAP---VPPWP 307



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 117 PNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169
           P L P       PQ  +P P  P+ P PP  PM P+PP+PP+ PM PM P+PP
Sbjct: 227 PALDPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPP 278



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 7/52 (13%)

Query: 113 QHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLP-------PQPP 157
           Q  +P L  P QQ  +P  ++ +  Q   PQ  V   QP         PQPP
Sbjct: 85  QQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPP 136


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 52/151 (34%), Positives = 69/151 (45%), Gaps = 36/151 (23%)

Query: 40  KWYQSIRP----PYPSYGYEPMGGWLHHQIIPVLSQQHP-PTHTLQPHHHIPVVPAQQPV 94
           +W + + P     YP  G +P+         P   Q+ P P   LQP          QP+
Sbjct: 298 RWKEPLMPRREEKYPLRGTDPLP--------PGQPQRIPLPGQPLQP----------QPI 339

Query: 95  I-PQQPM-MPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152
           + P QP  +P PGQH       H   +P P Q P  PQP+ P P +P+ PQP   P +PL
Sbjct: 340 LTPGQPQKIPTPGQHQPILTPGHSQPIPTPGQ-PLPPQPI-PTPGRPLTPQPIPTPGRPL 397

Query: 153 PPQP------PL---PPMFPMQPLPPMLPDL 174
            PQP      PL   PP+  ++P  PM P L
Sbjct: 398 TPQPIQMPGRPLRLPPPLRLLRPGQPMSPQL 428



 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 37/101 (36%), Positives = 45/101 (44%), Gaps = 11/101 (10%)

Query: 85  IPVVPAQQPVIPQQPMMP----VPGQHSMTPIQ-HHQPNLPPPAQQPYQPQPVQPQPHQP 139
           +P    Q+  +P QP+ P     PGQ    P    HQP L P   QP       P P QP
Sbjct: 319 LPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQPI------PTPGQP 372

Query: 140 MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
           + PQP   P +PL PQP   P  P+ P P  +P   L   P
Sbjct: 373 LPPQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPP 413



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 46/121 (38%), Positives = 55/121 (45%), Gaps = 23/121 (19%)

Query: 64  QIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ---PMMPVPGQHSMTPIQHHQPNLP 120
           Q IP   Q  P    L P H  P+    QP+ PQ    P  P+  Q   TP    +P  P
Sbjct: 346 QKIPTPGQHQP---ILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTP---GRPLTP 399

Query: 121 PPAQQPYQPQPVQP-----QPHQPMQPQPPVHPMQPLP-PQPPLPPMFP------MQPLP 168
            P Q P +P  + P     +P QPM PQ  +   Q LP PQP LPP  P      +QPLP
Sbjct: 400 QPIQMPGRPLRLPPPLRLLRPGQPMSPQ--LRQTQGLPLPQPLLPPGQPKSAGRPLQPLP 457

Query: 169 P 169
           P
Sbjct: 458 P 458


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 60.5 bits (145), Expect = 9e-10
 Identities = 46/127 (36%), Positives = 55/127 (43%), Gaps = 18/127 (14%)

Query: 66   IPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHH---------- 115
            IP+L+   P    L  H  +  +P Q PV P     P      + P  HH          
Sbjct: 884  IPLLAVAPPGVAALSIHSAVAQLPGQ-PVYPAA--FPQMAPTDVPPSPHHTVQNMRATPP 940

Query: 116  QPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLP--PMFPMQPLPPMLPD 173
            QP LPP    P  PQPV P P   + PQP + P    PPQP LP  PM P QP+ P  P 
Sbjct: 941  QPALPPQPTLP--PQPVLP-PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPA 997

Query: 174  LTLEAWP 180
            L +   P
Sbjct: 998  LPVRPEP 1004



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 46/123 (37%), Positives = 55/123 (44%), Gaps = 20/123 (16%)

Query: 74   PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQ-PV 132
            PP  TL P    PV+P Q P +P QP++P        P+   QP LPP    P QP  PV
Sbjct: 945  PPQPTLPPQ---PVLPPQ-PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPV 1000

Query: 133  QP---QPHQPMQPQPPVHP------MQPLP------PQPPLPPMFPMQPLPPMLPDLTLE 177
            +P   QPH P Q  P   P        P P       Q P  P+ P   L P LP++ L 
Sbjct: 1001 RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLP 1060

Query: 178  AWP 180
            A P
Sbjct: 1061 AAP 1063



 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 12/101 (11%)

Query: 75   PTHTLQPHHHIPVVPA--QQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV 132
            P HT+Q     P  PA   QP +P QP++P   Q ++ P    QP LPP   +P  PQPV
Sbjct: 928  PHHTVQNMRATPPQPALPPQPTLPPQPVLPP--QPTLPP----QPVLPPQPTRP--PQPV 979

Query: 133  QPQPHQPMQPQPPVHPMQPLPPQP-PLPPMFPMQPLPPMLP 172
             P P   + PQP + P   LP +P PL P  P Q  P   P
Sbjct: 980  LP-PQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019



 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 44/115 (38%), Positives = 55/115 (47%), Gaps = 22/115 (19%)

Query: 71  QQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQ--QPYQ 128
           QQ PP     P   +P V A QPV+P QP+ P           H  P L P +Q   P Q
Sbjct: 729 QQPPPLAQPTP---LPQVLAPQPVVPLQPVPP-----------HLPPYLAPASQVGAPAQ 774

Query: 129 PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPM---QPLPPMLPDLTLEAWP 180
            +P+Q  P  P+QP   V P   +PP P +PP+ P+     LPP LPDL     P
Sbjct: 775 LKPLQ-MPQAPLQPLAQVPPQ--MPPIPVVPPITPLAGIDGLPPALPDLPTATVP 826



 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 34/89 (38%), Positives = 41/89 (46%), Gaps = 8/89 (8%)

Query: 91  QQPVI-PQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPM 149
           QQP   P  P+  VP       +Q H P+ P  +  P  P P  P P  P QP PP    
Sbjct: 673 QQPTAAPGLPVGSVPAPACPPSLQQHFPD-PAMSFAPVLPPPSTPMPTGPGQPAPPGQQP 731

Query: 150 QPLPPQPPLP------PMFPMQPLPPMLP 172
            PL    PLP      P+ P+QP+PP LP
Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 52/174 (29%), Positives = 65/174 (37%), Gaps = 23/174 (13%)

Query: 11  LGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLS 70
           L  A   P+PP    P Y  FS  V+ P     S+  P P     P    L  Q + +  
Sbjct: 820 LPTATVPPVPP----PQY--FSPAVILP-----SLAAPLP-----PASPALPLQAVKL-- 861

Query: 71  QQHPPTHTLQPHHH--IPVVPAQQPVIPQQPM-MPVPGQHSMTPIQHHQPNLPPPAQQPY 127
             HPP   L       +P  PA  P++   P  +     HS       QP  P    Q  
Sbjct: 862 -PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ-M 919

Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181
            P  V P PH  +Q      P   LPPQP LPP   + P P + P   L   P+
Sbjct: 920 APTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 20/106 (18%)

Query: 69   LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPY- 127
            L+ +   +  L   H  P+   Q  V+   P  P P   S       +  LPPPA +P  
Sbjct: 1426 LTSELETSQPLAETHEAPLA-VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484

Query: 128  ---QPQPV--QPQPHQP-----------MQPQPPVHPMQPLPPQPP 157
                PQP   QP P  P             P PP+ P   +PPQPP
Sbjct: 1485 HSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP--TVPPQPP 1528



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 25/81 (30%), Positives = 28/81 (34%)

Query: 89  PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148
           PAQ    P     PV  Q   +   + QP   P       P P  P   Q   P P +  
Sbjct: 647 PAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSF 706

Query: 149 MQPLPPQPPLPPMFPMQPLPP 169
              LPP     P  P QP PP
Sbjct: 707 APVLPPPSTPMPTGPGQPAPP 727



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 16/55 (29%), Positives = 24/55 (43%)

Query: 100 MMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP 154
           + P   Q   +P +   P +P   Q  Y  Q  QP P +P +P+   H + P  P
Sbjct: 550 LQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLP 604



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 24/90 (26%), Positives = 32/90 (35%), Gaps = 2/90 (2%)

Query: 74   PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
            PP   L P     ++PA   ++PQ P        S+  +      L PPA  P    P  
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGI 1104

Query: 134  PQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163
              P   +  Q  V P+Q        PP  P
Sbjct: 1105 ASPCPTV--QLTVEPVQEEQASQDKPPGLP 1132



 Score = 27.3 bits (59), Expect = 8.2
 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 32/119 (26%)

Query: 86   PVVPAQQPV--IPQQPMMP----VPGQHSMTPIQHHQPNLP-----------PPAQQPYQ 128
            P+ P+  PV  +PQ    P    +P   S T  Q   P  P           P A+    
Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEA 1442

Query: 129  PQPVQPQPH--QPMQPQPPVH-------PMQPLPPQPPLPPMFPMQPLP------PMLP 172
            P  VQP      P  P P          P +PLPP  P P      P P      P+LP
Sbjct: 1443 PLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 48/138 (34%), Positives = 57/138 (41%), Gaps = 19/138 (13%)

Query: 67  PVLSQQHP---PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA 123
           P L Q  P   P+ T  PHH  P + AQQP     P  PVP   +M P    Q   PPP 
Sbjct: 825 PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA-PVPTPPAMPPGPQSQALHPPPR 883

Query: 124 QQPYQPQ---PVQPQPHQPMQPQPPVHPMQPLPPQ-------PPLPPMFPMQPLPPM-LP 172
           Q P  P    P Q QP  P  P       QP   Q        P  P+ P QP  P+  P
Sbjct: 884 QTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQP 943

Query: 173 DLTLEAW----PSTDKTK 186
            +++E      PST  T+
Sbjct: 944 AVSIEGQVSNPPSTSSTE 961



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 49/146 (33%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 47  PPYPSYGYEPMG-GWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPG 105
           P  PS G  P+    +     PV S   PP  +   H H P +P  QP + Q    PVP 
Sbjct: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPG-SQGSHIHCPQLP--QPALHQNSPSPVP- 836

Query: 106 QHSMTPIQHHQPNLPPPAQQPYQ--PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163
             S TP  HH P      Q P    P PV   P  P  P P    + P P Q P PP   
Sbjct: 837 --SRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMP--PGPQSQALHPPPRQTPTPPTTQ 892

Query: 164 M-QPLPPMLPDLTLEAWPSTDKTKRE 188
           + Q + P LP     A PS D+ +++
Sbjct: 893 LPQQVQPSLP-----AAPSADQPQQQ 913



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 20/99 (20%)

Query: 84  HIPVVPA--QQPVIPQQ----------PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP 131
           +IP+ P+  Q PV   Q          P+MP   Q S      H P LP PA     P P
Sbjct: 779 NIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI----HCPQLPQPALHQNSPSP 834

Query: 132 VQPQPHQPMQPQPPVHPMQP----LPPQPPLPPMFPMQP 166
           V  +   P    P +   QP    +P   P PP  P  P
Sbjct: 835 VPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGP 873



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 8/92 (8%)

Query: 94   VIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP----PVH-- 147
            V+ QQ  +P P   + T     QP  P   Q   QPQP  P    P  P+     PV   
Sbjct: 1840 VVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899

Query: 148  --PMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177
                Q  PP PP     P+   PP   ++ ++
Sbjct: 1900 KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 9/85 (10%)

Query: 79   LQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQH------HQPNLPPPAQQPY-QPQP 131
            LQ     PV P   P+ PQQ M+P   Q      Q       +Q   P P   P  Q QP
Sbjct: 2265 LQQQMGSPVQP--NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP 2322

Query: 132  VQPQPHQPMQPQPPVHPMQPLPPQP 156
                P   MQPQP  H + P    P
Sbjct: 2323 PHSSPSPRMQPQPSPHHVSPQTSSP 2347



 Score = 32.0 bits (71), Expect = 0.33
 Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 11/149 (7%)

Query: 43   QSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV----IPQQ 98
            Q +  P P+    P G        P  + Q  PT       ++P   A  PV       Q
Sbjct: 1845 QGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904

Query: 99   PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQP------HQPMQPQ-PPVHPMQP 151
               P P Q +  P+    P     A Q  +    Q Q        +P+Q Q PP+ PM P
Sbjct: 1905 VTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAP 1964

Query: 152  LPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
            +   PP     P   L P +    ++  P
Sbjct: 1965 MGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993



 Score = 32.0 bits (71), Expect = 0.33
 Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 12/113 (10%)

Query: 71   QQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMT-------PIQHHQPNLPPPA 123
            Q  PPT        +P  P     +  Q       Q  M        PIQH  P + P A
Sbjct: 1904 QVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963

Query: 124  QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQ---PLPPML 171
                 P P+   P   ++P      MQ  PP  Q  LP    +Q   P P M+
Sbjct: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM 2016



 Score = 27.7 bits (60), Expect = 6.3
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 125  QPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPML 171
            Q YQ + +Q Q   P+QP  P+ P Q + P     P    Q +P  L
Sbjct: 2258 QAYQQRLLQQQMGSPVQPN-PMSPQQHMLPNQAQSPHLQGQQIPNSL 2303



 Score = 27.3 bits (59), Expect = 8.2
 Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 11/77 (14%)

Query: 80   QPHHHIPVVPAQQPVIPQQPMMP-VPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQ 138
            QP    P +P  QP + Q P MP   G HS   +Q+  P +    Q+   P   Q QP Q
Sbjct: 2098 QPIPGQPGMPQGQPGL-QPPTMPGQQGVHSNPAMQNMNP-MQAGVQRAGLP---QQQPQQ 2152

Query: 139  PMQPQPPVHPMQPLPPQ 155
             +QP     PM  + PQ
Sbjct: 2153 QLQP-----PMGGMSPQ 2164


>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 12/90 (13%)

Query: 85  IPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP 144
           +P   +    +P  P+ P+P   S+ P+    P++PP    P  P P  P    P+ P P
Sbjct: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPM----PSIPPIPVPP--PVPTLP----PVPPVP 224

Query: 145 PVHPMQPLPPQPPLPPMFPMQPL--PPMLP 172
           P+ P+  +PP  PLPPM  M PL  PP+ P
Sbjct: 225 PIPPVPSVPPMTPLPPMSGMPPLNPPPVAP 254



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 8/94 (8%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
           PP  ++ P    P VP   PV P  P+ PVP    MTP+       P     P  P PV 
Sbjct: 200 PPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP------PMSGMPPLNPPPVA 253

Query: 134 PQPHQPMQPQPPVHPMQPLPPQ--PPLPPMFPMQ 165
           P P        P++    L P    PL P+ P+Q
Sbjct: 254 PLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQ 287



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181
           P    P+   P  P+ P P +  + P+P  PP+P   P+  LPP+ P   +   PS
Sbjct: 176 PSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPS 231


>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 12/90 (13%)

Query: 85  IPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP 144
           +P   +    +P  P+ P+P   S+ P+    P++PP    P  P P  P    P+ P P
Sbjct: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPM----PSIPPIPVPP--PVPTLP----PVPPVP 224

Query: 145 PVHPMQPLPPQPPLPPMFPMQPL--PPMLP 172
           P+ P+  +PP  PLPPM  M PL  PP+ P
Sbjct: 225 PIPPVPSVPPMTPLPPMSGMPPLNPPPVAP 254



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 8/94 (8%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
           PP  ++ P    P VP   PV P  P+ PVP    MTP+       P     P  P PV 
Sbjct: 200 PPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP------PMSGMPPLNPPPVA 253

Query: 134 PQPHQPMQPQPPVHPMQPLPPQ--PPLPPMFPMQ 165
           P P        P++    L P    PL P+ P+Q
Sbjct: 254 PLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQ 287



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 126 PYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181
           P    P+   P  P+ P P +  + P+P  PP+P   P+  LPP+ P   +   PS
Sbjct: 176 PSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPS 231


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 55/159 (34%), Positives = 62/159 (38%), Gaps = 25/159 (15%)

Query: 22  HPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQP 81
           HP  PG    +  V  P      + PP P  G  P    +H    P     HPP   + P
Sbjct: 316 HPPAPGVHPPTSGVHPPAP---GVHPPAP--GVHPPAPGVH----PPAPGVHPPAPGVHP 366

Query: 82  ------HHHIPVV-PAQQPVIPQQPMM--PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV 132
                 H   P V PA   V PQ P +  P PG H   P  H Q    PP   P  P  V
Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ----PPGVHPSAP-GV 421

Query: 133 QPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQPLPP 169
            PQP       P VHP  P+PP  +PPLP   P    PP
Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPP 460



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 57/172 (33%), Positives = 64/172 (37%), Gaps = 31/172 (18%)

Query: 19  LPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHT 78
           LPP P  P       E L P        PP P  G  P G     Q+ P     HPP   
Sbjct: 241 LPPRPPLP-------ESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV 293

Query: 79  LQP-----HHHIP-VVPAQQPVIPQQPMM---------PVPGQHSMTPIQH-HQPNLPPP 122
           + P     H   P V P    V P  P +         P PG H   P  H   P + PP
Sbjct: 294 VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPP 353

Query: 123 AQQPYQPQP-VQPQPHQPMQPQPP-VHPMQP-LPPQ-----PPLPPMFPMQP 166
           A   + P P V P P   + PQ P VHP  P + PQ     PP P M P  P
Sbjct: 354 APGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAP 405



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 47/145 (32%), Positives = 53/145 (36%), Gaps = 25/145 (17%)

Query: 45  IRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPT---HTLQPHHHIPVVPAQQPVIPQQPMM 101
           + PP P  G  P    +H    P  S  HPP    H   P  H P      P     P  
Sbjct: 308 VHPPAP--GVHPPAPGVH----PPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPA 361

Query: 102 P-------------VPGQHSMTPIQHHQ-PNLPPPAQQPYQPQP-VQPQPHQPMQPQPPV 146
           P              PG H   P  H Q P + PPA   +   P V PQP       P V
Sbjct: 362 PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGV 421

Query: 147 HPMQPLPPQPPLPPMFPMQPLPPML 171
           HP QP    P  P + P  P+PPML
Sbjct: 422 HP-QPPGVHPSNPGVHPPTPMPPML 445



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 43/137 (31%), Positives = 50/137 (36%), Gaps = 19/137 (13%)

Query: 22  HPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQP 81
           HP  PG    +  V  P      + PP PS G  P    +H    P +  Q P  H   P
Sbjct: 344 HPPAPGVHPPAPGVHPPAP---GVHPP-PSAGVHPQAPGVH-PAAPAVHPQAPGVHPPAP 398

Query: 82  HHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPM- 140
             H      Q P +  QP    PG H   P  H Q    PP   P  P    P P  PM 
Sbjct: 399 GMH-----PQAPGVHPQP----PGVHPSAPGVHPQ----PPGVHPSNPGVHPPTPMPPML 445

Query: 141 QPQPPVHPMQPLPPQPP 157
           +P  P      +PP PP
Sbjct: 446 RPPLPSEGPGNIPPPPP 462



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 38/107 (35%), Positives = 43/107 (40%), Gaps = 11/107 (10%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P L    PP   L P    P  P   P+ P  P  P P   S  P     P LPPPA   
Sbjct: 235 PPLMNGLPPRPPL-PESLPPPPPGGLPLPPMPPTGPAP---SGPP---GPPQLPPPAPGV 287

Query: 127 YQPQPVQPQPHQPMQPQPP-VHPMQP--LPPQPPL-PPMFPMQPLPP 169
           + P PV   P   + P  P VHP  P   PP P + PP   + P  P
Sbjct: 288 HPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAP 334



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 117 PNLPPPAQQPYQP--QPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172
           P  PP  ++P  P    + P+P  P    PP     PLPP PP  P     P PP LP
Sbjct: 224 PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLP 281



 Score = 35.8 bits (81), Expect = 0.023
 Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 7/82 (8%)

Query: 93  PVIPQQPMMPVPGQHSMTPIQHHQPNLPP-PAQQPYQPQPVQPQPHQPMQPQPPVHPMQP 151
           P  P  P  P   +    P+ +  P  PP P   P  P P    P  PM P  P     P
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLP--PPPPGGLPLPPMPPTGPAPSGPP 275

Query: 152 LPPQ--PPLPPMFPMQPL--PP 169
            PPQ  PP P + P  P+  PP
Sbjct: 276 GPPQLPPPAPGVHPPAPVVHPP 297



 Score = 35.0 bits (79), Expect = 0.039
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 16/88 (18%)

Query: 86  PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145
           P +PA  P + + P   + G     P+     +LPPP           P    P+ P PP
Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPE---SLPPP-----------PPGGLPLPPMPP 266

Query: 146 VHPMQPLPPQPP-LPPMFP-MQPLPPML 171
             P    PP PP LPP  P + P  P++
Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVV 294



 Score = 33.9 bits (76), Expect = 0.088
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 10/57 (17%)

Query: 124 QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP--------MQPLPPMLP 172
           ++P  P  +   P    +P PP+  M  LPP+PPLP   P        + P+PP  P
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPL--MNGLPPRPPLPESLPPPPPGGLPLPPMPPTGP 269


>gi|195232763 ADAM metallopeptidase domain 29 preproprotein [Homo
           sapiens]
          Length = 820

 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P+  QQ   T + +    I   P + P   Q  +MP   Q  +TP Q H   +P  +Q P
Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172
             P   QP+   P Q QPPV P Q  P   P    PP+ P Q  P ++P
Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%)

Query: 70  SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           SQ  PP    Q H  +    +Q PV P Q    +MP   Q  + P Q H P L P   QP
Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
                    P  P Q QP + P Q  PP  P
Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819


>gi|195232761 ADAM metallopeptidase domain 29 preproprotein [Homo
           sapiens]
          Length = 820

 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P+  QQ   T + +    I   P + P   Q  +MP   Q  +TP Q H   +P  +Q P
Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172
             P   QP+   P Q QPPV P Q  P   P    PP+ P Q  P ++P
Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%)

Query: 70  SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           SQ  PP    Q H  +    +Q PV P Q    +MP   Q  + P Q H P L P   QP
Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
                    P  P Q QP + P Q  PP  P
Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819


>gi|195232759 ADAM metallopeptidase domain 29 preproprotein [Homo
           sapiens]
          Length = 820

 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P+  QQ   T + +    I   P + P   Q  +MP   Q  +TP Q H   +P  +Q P
Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172
             P   QP+   P Q QPPV P Q  P   P    PP+ P Q  P ++P
Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%)

Query: 70  SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           SQ  PP    Q H  +    +Q PV P Q    +MP   Q  + P Q H P L P   QP
Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
                    P  P Q QP + P Q  PP  P
Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819


>gi|73765552 ADAM metallopeptidase domain 29 preproprotein [Homo
           sapiens]
          Length = 820

 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P+  QQ   T + +    I   P + P   Q  +MP   Q  +TP Q H   +P  +Q P
Sbjct: 703 PIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPP 762

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP---PQPPLPPMFPMQPLPPMLP 172
             P   QP+   P Q QPPV P Q  P   P    PP+ P Q  P ++P
Sbjct: 763 VTPSQSQPRV-MPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMP 810



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 13/91 (14%)

Query: 70  SQQHPPTHTLQPHHHIPVVPAQQPVIPQQP---MMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           SQ  PP    Q H  +    +Q PV P Q    +MP   Q  + P Q H P L P   QP
Sbjct: 739 SQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSH-PQLTPSQSQP 797

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
                    P  P Q QP + P Q  PP  P
Sbjct: 798 ---------PVTPSQRQPQLMPSQSQPPVTP 819


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 58.5 bits (140), Expect = 3e-09
 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 14/104 (13%)

Query: 67   PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
            P+L ++ PPT         P  P  QP  P  P  P P   S  P+    P+ PPP   P
Sbjct: 1451 PLLEEKPPPTP--------PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP 1502

Query: 127  YQPQPVQPQPHQPMQP------QPPVHPMQPLPPQPPLPPMFPM 164
              P P  P P  P  P       PP  P  P P  P LP   P+
Sbjct: 1503 PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 36/98 (36%), Positives = 43/98 (43%), Gaps = 18/98 (18%)

Query: 86   PVVPAQQPVIPQQPMMP-VPGQHSM-TP----IQHHQPNLPPPAQQPYQPQPVQPQPHQP 139
            P+ PA    +P  P +P +P  +S  TP    ++   P  PPPA  P    P  P P QP
Sbjct: 1423 PLAPAA--AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQP 1480

Query: 140  MQPQPPV--------HPMQPLPPQPPLPPMFPMQPLPP 169
              P PP          P  PLPP P  PP  P  P PP
Sbjct: 1481 ALPSPPPLVAPTPSSPPPPPLPPPP--PPAMPSPPPPP 1516



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 19/98 (19%)

Query: 91   QQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP---VQPQPHQPMQP--QPP 145
            + P++ ++P    P      P    QP  PPP  QP  P P   V P P  P  P   PP
Sbjct: 1449 EPPLLEEKP----PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504

Query: 146  VHPMQPLPPQPP--------LPPMFPMQPLP--PMLPD 173
              P  P PP PP         PP  P  P P  P LPD
Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 29/125 (23%)

Query: 74  PPT-HTLQPHHHIPVVPAQQP----VIPQQPMMPVP----------------GQHSMTPI 112
           PPT  + QP  H  ++ A  P    V+P  P   +P                G H + P 
Sbjct: 768 PPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPA 827

Query: 113 QHH-QPNLPPPAQQPYQPQPVQPQPH------QPMQPQPPVHPMQPLPPQPPLPPMF-PM 164
                P  PPP   P  P P+Q + H      +P  P P + P + L P   +  +   +
Sbjct: 828 TRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGAL 887

Query: 165 QPLPP 169
           +PLPP
Sbjct: 888 EPLPP 892



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 24/75 (32%), Positives = 26/75 (34%), Gaps = 1/75 (1%)

Query: 86   PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145
            P  PA  P  P  P     G    TP     PN PP        +P+      P Q  PP
Sbjct: 982  PGPPAYDPYGPYCPGR-ASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040

Query: 146  VHPMQPLPPQPPLPP 160
              P  P PP P   P
Sbjct: 1041 PPPPPPPPPAPASEP 1055



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 14/91 (15%)

Query: 95  IPQQPMMPVPGQHSMTPIQHHQ------PNLP---PPAQQPYQPQPVQPQPH-QPMQPQP 144
           + + P  P P   S  P  H        P+LP   PP      P  +   P   P   + 
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKV 819

Query: 145 PVHPMQPLP----PQPPLPPMFPMQPLPPML 171
            VH ++P      PQPP PP  P  P+P  L
Sbjct: 820 GVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 14/82 (17%)

Query: 69  LSQQHPP-----THTLQPHHHIPVVPAQQPVIPQQ-PMMPVPGQHSMTPIQHHQPNLPPP 122
           LS Q PP        L PH  + + P+Q P +P       + G   + P       L P 
Sbjct: 168 LSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP-----AGLGPA 222

Query: 123 AQQPYQPQPVQPQP---HQPMQ 141
              PY+P P  P P   H P Q
Sbjct: 223 QTPPYRPGPPDPPPPPRHLPTQ 244



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 13/31 (41%), Positives = 15/31 (48%)

Query: 136  PHQPMQPQPPVHPMQPLPPQPPLPPMFPMQP 166
            P  P +  PP  P + L PQPP  P  P  P
Sbjct: 1306 PLSPPKSVPPSVPARGLQPQPPATPAVPHPP 1336



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 5/61 (8%)

Query: 102  PVPGQHS---MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158
            PVP + S     P+     + PPP      P+P  P+  +    +PP    +   P+PP 
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPE--KTTSEKPPEQTPETAMPEPPA 1728

Query: 159  P 159
            P
Sbjct: 1729 P 1729


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 57.4 bits (137), Expect = 7e-09
 Identities = 43/124 (34%), Positives = 51/124 (41%), Gaps = 22/124 (17%)

Query: 39   LKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ 98
            L+  Q ++PP P              ++P +  Q  P   L P  H    P+ Q  + QQ
Sbjct: 932  LQQLQKVQPPTP--------------LLPSVKVQSQPPPPLPPPPH----PSVQQQLQQQ 973

Query: 99   PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP---MQPLPPQ 155
            P  P P Q    P Q HQP   P   QP Q      QP  P   QPP HP    QP PPQ
Sbjct: 974  PPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP-HPPPGQQPPPPQ 1032

Query: 156  PPLP 159
            P  P
Sbjct: 1033 PAKP 1036



 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 43/157 (27%), Positives = 64/157 (40%), Gaps = 31/157 (19%)

Query: 45  IRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVP 104
           + P  P   ++P+G    H   P+L   H P   L PH   P   +  P + Q  ++  P
Sbjct: 808 LEPQLPGSVFDPIG----HFTQPIL---HLPQPELPPHLPQPPEHSTPPHLNQHAVVSPP 860

Query: 105 GQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL--PPQ------- 155
             H+  P    QP+ P        P+P +P    P   Q P+ P  P+  PPQ       
Sbjct: 861 ALHNALP---QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917

Query: 156 PPLPPMFPM------------QPLPPMLPDLTLEAWP 180
           PP PP+  M            QP  P+LP + +++ P
Sbjct: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP 954



 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 54/177 (30%), Positives = 63/177 (35%), Gaps = 45/177 (25%)

Query: 16   AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPP 75
            A  LPP P  P  ++ +    TPL        P P     P           +L  + PP
Sbjct: 877  AAALPPKPARPPAVSPAL-TQTPLL-------PQPPMAQPPQ---------VLLEDEEPP 919

Query: 76   THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA---------QQP 126
               L        +   Q V P  P++P     S  P     P LPPP          QQP
Sbjct: 920  APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP-----PPLPPPPHPSVQQQLQQQP 974

Query: 127  YQPQPVQPQPHQPMQPQPPVHPM------------QPLPPQPPLPPMFP--MQPLPP 169
              P P QPQP    Q QPP  P+            QP PPQ   PP  P   QP PP
Sbjct: 975  PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 34/103 (33%), Positives = 38/103 (36%), Gaps = 21/103 (20%)

Query: 73  HPPTHTLQPHHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQP 131
           HP     + HHH      Q P  +PQQP                    PPP QQP  P P
Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQP--------------------PPPPQQPPPPPP 769

Query: 132 VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDL 174
            Q Q   P  P PP  P Q  P     PP F    +P + P L
Sbjct: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 10/159 (6%)

Query: 17  MPLPPHPGHPGYINFSYEVLTPLKWYQSI--RPPYPSYGYE--PMGGWLHHQIIPVLSQQ 72
           +P PP    P ++N  + V++P   + ++  +P  PS      P        + P L+Q 
Sbjct: 839 LPQPPEHSTPPHLN-QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQT 897

Query: 73  HPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPN---LPPPAQQPYQP 129
             P     P    P V  +    P  P+  +  Q  +  +Q  QP    LP    Q   P
Sbjct: 898 --PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP 955

Query: 130 QPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168
            P+ P PH  +Q Q    P  P PPQP  PP    QP P
Sbjct: 956 PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 20/104 (19%)

Query: 96  PQQPMMPVPGQHSMTP-IQHHQPNLPPPAQQPYQPQPVQPQ-----------PHQPMQPQ 143
           P    +P   Q S  P  Q  QPN PP    P+    V P            P QP+Q  
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250

Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPSTDKTKR 187
           PPV P QP PP  P P   P+Q  PP+     + A P   KTK+
Sbjct: 251 PPV-PPQPQPPPAPAPQ--PVQSHPPI-----IAATPQPVKTKK 286



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 60/231 (25%), Positives = 78/231 (33%), Gaps = 64/231 (27%)

Query: 18   PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTH 77
            PLPP P HP       +   P    Q   PP   +   P    L         QQ PP  
Sbjct: 957  PLPPPP-HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQ 1015

Query: 78   TLQPHHHIPVVPAQQPVIPQ--QPMMPVPGQHSM-----------------TPIQHHQPN 118
              QP H     P QQP  PQ  +P   +   HS                  +P+  H P 
Sbjct: 1016 GQQPPHP---PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQ 1072

Query: 119  LPP--------PAQQPYQPQP--------VQPQP---------HQP----------MQPQ 143
            +          P QQ  QP+         VQPQP         H P          ++P+
Sbjct: 1073 MSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE 1132

Query: 144  PPVHPMQ-----PLPPQPPLPPMFPMQP-LPPMLPDLTLEAWPSTDKTKRE 188
            PP HP        LP +P + P+   +P + P   +      P  DK K+E
Sbjct: 1133 PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQE 1183



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 14/69 (20%)

Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPD 173
           HHQ     PA  P QP P    P QP  P PP    QP PP PP           P +P 
Sbjct: 742 HHQQMQQAPAPVPQQPPP---PPQQPPPPPPPQQQQQPPPPPPP-----------PSMPQ 787

Query: 174 LTLEAWPST 182
               A  S+
Sbjct: 788 QAAPAMKSS 796



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 49/173 (28%), Positives = 57/173 (32%), Gaps = 57/173 (32%)

Query: 62  HHQII---PVLSQQHPPTHTLQPHHHIPVVPAQQ----PVIPQQPMMPVPGQHS------ 108
           HHQ +   P    Q PP    QP    P    QQ    P  P  P    P   S      
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801

Query: 109 ---------------MTPIQHH-QP--NLPPPAQQPYQPQPVQ--PQPH----------- 137
                            PI H  QP  +LP P   P+ PQP +    PH           
Sbjct: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861

Query: 138 ----QPMQPQPPVHPMQPLPPQPPLPP-------MFPMQPLPPML--PDLTLE 177
                P QP  P +    LPP+P  PP         P+ P PPM   P + LE
Sbjct: 862 LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLE 914



 Score = 35.8 bits (81), Expect = 0.023
 Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 24/106 (22%)

Query: 71  QQHPPTHTLQPHHHIPVVP---AQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP-PAQQP 126
           Q +PP     PH    V P    Q PV+   P  P+     + P    QP  PP PA QP
Sbjct: 212 QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP----QPQPPPAPAPQP 267

Query: 127 YQPQP----VQPQPHQPMQ------------PQPPVHPMQPLPPQP 156
            Q  P      PQP +  +               P+H    LPP+P
Sbjct: 268 VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 57.4 bits (137), Expect = 7e-09
 Identities = 31/69 (44%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 99  PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158
           PM P PGQ    P        PPP QQ  QP P QP P QP   QPP HP      QPP 
Sbjct: 46  PMGPGPGQSGPKP----PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101

Query: 159 PPMFPMQPL 167
           PP    +P+
Sbjct: 102 PPQDSSKPV 110



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 45/137 (32%), Positives = 48/137 (35%), Gaps = 17/137 (12%)

Query: 46  RPPYPSYGYE----PMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMM 101
           R P P  G      PMG        P  S   PP     PH      P QQP  PQQP  
Sbjct: 32  RSPPPGMGLNQNRGPMGPG------PGQSGPKPPIPPPPPHQQQQQPPPQQPP-PQQPPP 84

Query: 102 PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ-PQPHQPMQPQPPVHPMQP--LPPQPPL 158
             P  H   P  H Q   PPP Q   +P   Q P P   +   PP     P   PP    
Sbjct: 85  HQPPPH---PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141

Query: 159 PPMFPMQPLPPMLPDLT 175
           PP     P P   P +T
Sbjct: 142 PPGSGPGPTPTPPPAVT 158



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 34/116 (29%), Positives = 37/116 (31%), Gaps = 14/116 (12%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--------- 117
           P   QQ PP     P    P  P   P   QQ   P P Q S  P+    P         
Sbjct: 65  PHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSA 124

Query: 118 ----NLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169
               +  PPA  P    P    P     P P V    P  P PP PP   +   PP
Sbjct: 125 PPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP-PPTPPSSGVPTTPP 179



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 36/111 (32%), Positives = 39/111 (35%), Gaps = 15/111 (13%)

Query: 72  QHPPTHTLQPH-----HHIPVVPAQ---QPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPA 123
           Q PP H   PH        P  P Q   +PV+ Q P  P PG  S  P     P   PP 
Sbjct: 80  QQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG-PAPGVGSAPPASSSAPPATPPT 138

Query: 124 Q--QPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQ---PPLPPMFPMQPLPP 169
               P       P P   +   PP  P  P PP    P  PP     P PP
Sbjct: 139 SGAPPGSGPGPTPTPPPAVTSAPPGAP-PPTPPSSGVPTTPPQAGGPPPPP 188



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 6/61 (9%)

Query: 115 HQPNLPPPA------QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLP 168
           H    PPP       + P  P P Q  P  P+ P PP    Q  PPQ P P   P    P
Sbjct: 29  HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88

Query: 169 P 169
           P
Sbjct: 89  P 89



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 26/87 (29%), Positives = 27/87 (31%), Gaps = 5/87 (5%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
           PPT    P       P   P +   P    PG    TP     P  PP A  P  P    
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAP----PGAPPPTPPSSGVPTTPPQAGGPPPPPAAV 191

Query: 134 PQPHQ-PMQPQPPVHPMQPLPPQPPLP 159
           P P   P Q   P  P     P  P P
Sbjct: 192 PGPGPGPKQGPGPGGPKGGKMPGGPKP 218


>gi|114431236 zinc finger protein 462 [Homo sapiens]
          Length = 2506

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 30/62 (48%), Positives = 34/62 (54%), Gaps = 5/62 (8%)

Query: 109 MTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP-VHPMQPLPPQPPLPPMFPMQPL 167
           + P+Q  QP  PPP   P  P P QPQP Q  QPQPP + P   +PPQP   P    QP 
Sbjct: 534 LDPLQQQQPPQPPPPPPP--PPPSQPQPLQ--QPQPPQLQPPHQVPPQPQTQPPPTQQPQ 589

Query: 168 PP 169
           PP
Sbjct: 590 PP 591



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 32/67 (47%), Positives = 34/67 (50%), Gaps = 7/67 (10%)

Query: 89  PAQQPVIPQQPMMPVPGQHSMT-PIQHHQP-NLPPPAQQPYQPQPVQPQPHQPMQPQPPV 146
           P QQ   PQ P  P P   S   P+Q  QP  L PP Q P QPQ  QP P Q  QPQPP 
Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQ-TQPPPTQ--QPQPPT 592

Query: 147 H--PMQP 151
              P+ P
Sbjct: 593 QAAPLHP 599



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 28/67 (41%), Positives = 31/67 (46%), Gaps = 13/67 (19%)

Query: 93  PVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQ-QP-YQPQPVQPQPHQPMQPQPPVHPMQ 150
           P+  QQP  P P            P  PPP+Q QP  QPQP Q QP   + PQP   P  
Sbjct: 536 PLQQQQPPQPPP-----------PPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPP 584

Query: 151 PLPPQPP 157
              PQPP
Sbjct: 585 TQQPQPP 591



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 11/88 (12%)

Query: 51  SYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMP-VPGQHSM 109
           SY    + G     ++  L QQ PP    QP    P  P  QP   QQP  P +   H +
Sbjct: 519 SYESSSINGRKSGVMLDPLQQQQPP----QPPPPPPPPPPSQPQPLQQPQPPQLQPPHQV 574

Query: 110 TPIQHHQPNLPPPAQQPYQP---QPVQP 134
            P    QP   PP QQP  P    P+ P
Sbjct: 575 PPQPQTQP---PPTQQPQPPTQAAPLHP 599



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/33 (48%), Positives = 17/33 (51%)

Query: 139 PMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPML 171
           P+Q Q P  P  P PP PP  P    QP PP L
Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQL 568



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 26/68 (38%), Positives = 30/68 (44%), Gaps = 9/68 (13%)

Query: 35  VLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV 94
           +L PL+  Q  +PP P     P       Q  P L Q  PP   LQP H +P  P  QP 
Sbjct: 533 MLDPLQQQQPPQPPPPPPPPPPS------QPQP-LQQPQPPQ--LQPPHQVPPQPQTQPP 583

Query: 95  IPQQPMMP 102
             QQP  P
Sbjct: 584 PTQQPQPP 591



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 7/55 (12%)

Query: 135 QPHQPMQPQPPVHPMQPLPPQP---PLPPMF----PMQPLPPMLPDLTLEAWPST 182
           Q  QP QP PP  P  P  PQP   P PP       + P P   P  T +  P T
Sbjct: 538 QQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPT 592



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 13/28 (46%), Positives = 14/28 (50%)

Query: 145 PVHPMQPLPPQPPLPPMFPMQPLPPMLP 172
           P+   QP  P PP PP  P QP P   P
Sbjct: 536 PLQQQQPPQPPPPPPPPPPSQPQPLQQP 563


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 54.7 bits (130), Expect = 5e-08
 Identities = 50/186 (26%), Positives = 65/186 (34%), Gaps = 20/186 (10%)

Query: 18  PLPPHPGHPGYINFSYEVLTPLKWYQSIR-------------PPYPSYGYEPMGGWLHHQ 64
           P  P  GH GY    Y   TP ++  +++                P YG +   G+    
Sbjct: 408 PSGPQQGH-GYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466

Query: 65  IIPVLSQQHP-PTHTLQPHHHIPV--VPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP 121
             P  +QQ P P     P+   P    P  QP   QQP    P   S  P    QP+ PP
Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526

Query: 122 PAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181
             Q P      Q    Q  Q QPP    Q    Q P     P QP P  L        P 
Sbjct: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ---AQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583

Query: 182 TDKTKR 187
           + ++++
Sbjct: 584 SQQSQQ 589



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 45/161 (27%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 12  GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPY--PSYGYEPMGGWLHHQII--- 66
           G ++   +PP+ G  G   +  +  TP    QS  P    P Y  +P     H Q     
Sbjct: 444 GLSYTQQIPPY-GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502

Query: 67  ------PVLSQQHPPTH---TLQPHHHIPV-VPAQQPVIPQQPMM--PVPGQHSMTPIQH 114
                 P L    PP     +  PH   P   P+QQ    Q P    P     + +P Q 
Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562

Query: 115 HQPNLPPP---AQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152
            QP  P P   +QQ   PQP   Q  Q    Q    P Q L
Sbjct: 563 QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603



 Score = 32.0 bits (71), Expect = 0.33
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 13/84 (15%)

Query: 89   PAQQPVIPQQPMM-PVPGQHSMTP-IQHHQPNLPPPAQQPYQPQPVQPQP------HQPM 140
            P   P  P  PM  P P  +   P +Q+H P +  PA  P +P   +  P      H  M
Sbjct: 1553 PPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLP-RPMENRTSPSKSPFLHSGM 1611

Query: 141  QPQ---PPVHPMQPLPPQPPLPPM 161
            + Q   PPV P   + P P  PPM
Sbjct: 1612 KMQKAGPPV-PASHIAPAPVQPPM 1634



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 17/92 (18%)

Query: 67   PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
            PV     PP    QP       P+ Q  IPQ          S  P+     N   P++ P
Sbjct: 1560 PVPPMTRPPPSNYQPP------PSMQNHIPQVS--------SPAPLPRPMENRTSPSKSP 1605

Query: 127  YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPL 158
            +    ++ Q   P  P P  H + P P QPP+
Sbjct: 1606 FLHSGMKMQKAGP--PVPASH-IAPAPVQPPM 1634



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%)

Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQP------MQPQP-----PVHPMQPLPPQPPLPPMF 162
           HH P  P  +    QP    PQP  P      M+PQP     P    Q  P  P     +
Sbjct: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGY 417

Query: 163 PMQPLPPMLP 172
           P QP     P
Sbjct: 418 PGQPYGSQTP 427



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 7/64 (10%)

Query: 89  PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQ-------PYQPQPVQPQPHQPMQ 141
           P     +P   M P P       I H   N    AQ        P  PQ   PQP   + 
Sbjct: 713 PLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772

Query: 142 PQPP 145
           P+ P
Sbjct: 773 PRQP 776


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 54.7 bits (130), Expect = 5e-08
 Identities = 50/186 (26%), Positives = 65/186 (34%), Gaps = 20/186 (10%)

Query: 18  PLPPHPGHPGYINFSYEVLTPLKWYQSIR-------------PPYPSYGYEPMGGWLHHQ 64
           P  P  GH GY    Y   TP ++  +++                P YG +   G+    
Sbjct: 408 PSGPQQGH-GYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466

Query: 65  IIPVLSQQHP-PTHTLQPHHHIPV--VPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPP 121
             P  +QQ P P     P+   P    P  QP   QQP    P   S  P    QP+ PP
Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526

Query: 122 PAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPS 181
             Q P      Q    Q  Q QPP    Q    Q P     P QP P  L        P 
Sbjct: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ---AQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583

Query: 182 TDKTKR 187
           + ++++
Sbjct: 584 SQQSQQ 589



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 45/161 (27%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 12  GAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPY--PSYGYEPMGGWLHHQII--- 66
           G ++   +PP+ G  G   +  +  TP    QS  P    P Y  +P     H Q     
Sbjct: 444 GLSYTQQIPPY-GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502

Query: 67  ------PVLSQQHPPTH---TLQPHHHIPV-VPAQQPVIPQQPMM--PVPGQHSMTPIQH 114
                 P L    PP     +  PH   P   P+QQ    Q P    P     + +P Q 
Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562

Query: 115 HQPNLPPP---AQQPYQPQPVQPQPHQPMQPQPPVHPMQPL 152
            QP  P P   +QQ   PQP   Q  Q    Q    P Q L
Sbjct: 563 QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603



 Score = 28.5 bits (62), Expect = 3.7
 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%)

Query: 114 HHQPNLPPPAQQPYQPQPVQPQPHQP------MQPQP-----PVHPMQPLPPQPPLPPMF 162
           HH P  P  +    QP    PQP  P      M+PQP     P    Q  P  P     +
Sbjct: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGY 417

Query: 163 PMQPLPPMLP 172
           P QP     P
Sbjct: 418 PGQPYGSQTP 427



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 7/64 (10%)

Query: 89  PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQ-------PYQPQPVQPQPHQPMQ 141
           P     +P   M P P       I H   N    AQ        P  PQ   PQP   + 
Sbjct: 713 PLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772

Query: 142 PQPP 145
           P+ P
Sbjct: 773 PRQP 776



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 7/66 (10%)

Query: 102  PVPGQHSMTPIQHHQPNLPPPAQQPYQPQPV---QPQPHQPMQPQ---PPVHPMQPLPPQ 155
            P P Q +    Q  Q + P P  +P + +      P  H  M+ Q   PPV P   + P 
Sbjct: 1353 PFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV-PASHIAPA 1411

Query: 156  PPLPPM 161
            P  PPM
Sbjct: 1412 PVQPPM 1417



 Score = 27.3 bits (59), Expect = 8.2
 Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 7/70 (10%)

Query: 89   PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148
            P+QQ  + QQ         S  P+     N   P++ P+    ++ Q   P  P P  H 
Sbjct: 1355 PSQQTTMYQQQQQV----SSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGP--PVPASH- 1407

Query: 149  MQPLPPQPPL 158
            + P P QPP+
Sbjct: 1408 IAPAPVQPPM 1417


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 87  VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143
           V PA     P  P +P PG    TP     P    P  +Q P QPQ P  P PH  +Q  
Sbjct: 193 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 249

Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170
           P +HP +P  P PP P   P  PL P+
Sbjct: 250 PALHPQRPPSPHPP-PHPSPHPPLQPL 275



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%)

Query: 75  PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132
           P+ T  P    P   +Q P  PQ P  PVP  H    P  H Q P  P P   P    P+
Sbjct: 214 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 272

Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169
           QP      QP  P   QPP+H   P  P      P L    P QP  LPP
Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%)

Query: 74  PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125
           PPT  +      Q H H P +    P      + P P    ++ +  HH P+  PPP Q 
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 436

Query: 126 PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177
             Q QP+   P QP        + P P  HP   L    P PP      +P   P +T  
Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 496

Query: 178 AWPST 182
             PST
Sbjct: 497 TCPST 501



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%)

Query: 75  PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134
           P  +L  HH     P    ++PQ    P+P   +  P      NLPPP      P    P
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 468

Query: 135 QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172
                + PQPP   HP  P  P P  PP  P    PP  P
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 508



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%)

Query: 16  AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68
           A PL  HPG P                    PP  S G  P+G      + H  + +P  
Sbjct: 305 AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 349

Query: 69  ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119
              L  Q PP    QP   +P  P   P I   P  P+P Q        H P+L      
Sbjct: 350 QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 403

Query: 120 -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168
                  PPPA +P          H P    PP+  M   QPLP  P  PP +   Q LP
Sbjct: 404 SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 460

Query: 169 P 169
           P
Sbjct: 461 P 461



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%)

Query: 62  HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115
           H Q  P L  Q PP+    PH   H P+ P    A QP  P     P+ GQ    P   H
Sbjct: 245 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 301

Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147
                P  Q P  PQP  + PQ                PH  +Q           QPP  
Sbjct: 302 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 361

Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170
             QPLPP P   P     P  P+
Sbjct: 362 --QPLPPAPLAMPHIKPPPTTPI 382



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%)

Query: 73  HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127
           HPP   L P    +P  PAQ P + Q Q + P P  H  T +    P  PP AQ P+   
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 488

Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
            P P+ P P  P    PP  P      QPP
Sbjct: 489 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 515



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%)

Query: 47  PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103
           P  P+ G  P    +  Q  P  SQ    P   T   PH HI   PA  P   Q+P  P 
Sbjct: 205 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 261

Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156
           P  H  +P    QP L   A QP  P   QP  H    P P  H +Q       P PPQP
Sbjct: 262 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 317

Query: 157 -PLPP 160
             LPP
Sbjct: 318 FGLPP 322



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%)

Query: 20  PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73
           PPHP  HP         L PL      +P  PS+   P+ G         Q  P+L    
Sbjct: 263 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128
           PP    QP    P     Q  +   P    P      P     +Q  Q    PP +QP  
Sbjct: 314 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 365

Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175
           P P     ++P P  P+ PQ P       PP    P  F M    P PP L  L+
Sbjct: 366 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 419


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 87  VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143
           V PA     P  P +P PG    TP     P    P  +Q P QPQ P  P PH  +Q  
Sbjct: 747 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 803

Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170
           P +HP +P  P PP P   P  PL P+
Sbjct: 804 PALHPQRPPSPHPP-PHPSPHPPLQPL 829



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%)

Query: 75  PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132
           P+ T  P    P   +Q P  PQ P  PVP  H    P  H Q P  P P   P    P+
Sbjct: 768 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826

Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169
           QP      QP  P   QPP+H   P  P      P L    P QP  LPP
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%)

Query: 74   PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125
            PPT  +      Q H H P +    P      + P P    ++ +  HH P+  PPP Q 
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 990

Query: 126  PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177
              Q QP+   P QP        + P P  HP   L    P PP      +P   P +T  
Sbjct: 991  MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050

Query: 178  AWPST 182
              PST
Sbjct: 1051 TCPST 1055



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%)

Query: 75   PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134
            P  +L  HH     P    ++PQ    P+P   +  P      NLPPP      P    P
Sbjct: 971  PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 1022

Query: 135  QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172
                 + PQPP   HP  P  P P  PP  P    PP  P
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%)

Query: 16   AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68
            A PL  HPG P                    PP  S G  P+G      + H  + +P  
Sbjct: 859  AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 903

Query: 69   ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119
               L  Q PP    QP   +P  P   P I   P  P+P Q        H P+L      
Sbjct: 904  QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 957

Query: 120  -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168
                   PPPA +P          H P    PP+  M   QPLP  P  PP +   Q LP
Sbjct: 958  SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014

Query: 169  P 169
            P
Sbjct: 1015 P 1015



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%)

Query: 62  HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115
           H Q  P L  Q PP+    PH   H P+ P    A QP  P     P+ GQ    P   H
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 855

Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147
                P  Q P  PQP  + PQ                PH  +Q           QPP  
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915

Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170
             QPLPP P   P     P  P+
Sbjct: 916 --QPLPPAPLAMPHIKPPPTTPI 936



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%)

Query: 73   HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127
            HPP   L P    +P  PAQ P + Q Q + P P  H  T +    P  PP AQ P+   
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 1042

Query: 128  QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
             P P+ P P  P    PP  P      QPP
Sbjct: 1043 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 1069



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%)

Query: 47  PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103
           P  P+ G  P    +  Q  P  SQ    P   T   PH HI   PA  P   Q+P  P 
Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 815

Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156
           P  H  +P    QP L   A QP  P   QP  H    P P  H +Q       P PPQP
Sbjct: 816 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 871

Query: 157 -PLPP 160
             LPP
Sbjct: 872 FGLPP 876



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%)

Query: 20  PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73
           PPHP  HP         L PL      +P  PS+   P+ G         Q  P+L    
Sbjct: 817 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128
           PP    QP    P     Q  +   P    P      P     +Q  Q    PP +QP  
Sbjct: 868 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 919

Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175
           P P     ++P P  P+ PQ P       PP    P  F M    P PP L  L+
Sbjct: 920 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 973


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 87  VVPAQQPVIPQQPMMPVPGQHSMTPIQHHQP--NLPPPAQQPYQPQ-PVQPQPHQPMQPQ 143
           V PA     P  P +P PG    TP     P    P  +Q P QPQ P  P PH  +Q  
Sbjct: 747 VTPAPSSAPPGTPQLPTPGP---TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 803

Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPM 170
           P +HP +P  P PP P   P  PL P+
Sbjct: 804 PALHPQRPPSPHPP-PHPSPHPPLQPL 829



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 40/110 (36%), Positives = 44/110 (40%), Gaps = 16/110 (14%)

Query: 75  PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQH-SMTPIQHHQ-PNLPPPAQQPYQPQPV 132
           P+ T  P    P   +Q P  PQ P  PVP  H    P  H Q P  P P   P    P+
Sbjct: 768 PSATAVPPQGSPTA-SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826

Query: 133 QP------QPHQPMQPQPPVHPMQPLPPQ-----PPLPPMFPMQP--LPP 169
           QP      QP  P   QPP+H   P  P      P L    P QP  LPP
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 16/125 (12%)

Query: 74   PPTHTL------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQ-HHQPNL-PPPAQQ 125
            PPT  +      Q H H P +    P      + P P    ++ +  HH P+  PPP Q 
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 990

Query: 126  PYQPQPVQPQPHQP--------MQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLE 177
              Q QP+   P QP        + P P  HP   L    P PP      +P   P +T  
Sbjct: 991  MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050

Query: 178  AWPST 182
              PST
Sbjct: 1051 TCPST 1055



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/100 (32%), Positives = 38/100 (38%), Gaps = 10/100 (10%)

Query: 75   PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134
            P  +L  HH     P    ++PQ    P+P   +  P      NLPPP      P    P
Sbjct: 971  PLSSLSTHHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQSQNLPPP------PASHPP 1022

Query: 135  QPHQPMQPQPPV--HPMQPLPPQPPLPPMFPMQPLPPMLP 172
                 + PQPP   HP  P  P P  PP  P    PP  P
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 53/181 (29%), Positives = 63/181 (34%), Gaps = 51/181 (28%)

Query: 16   AMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMG-----GWLHHQI-IPV- 68
            A PL  HPG P                    PP  S G  P+G      + H  + +P  
Sbjct: 859  AGPLLQHPGPPQPFGL---------------PPQASQGQAPLGTSPAAAYPHTSLQLPAS 903

Query: 69   ---LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNL------ 119
               L  Q PP    QP   +P  P   P I   P  P+P Q        H P+L      
Sbjct: 904  QSALQSQQPPRE--QP---LPPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPF 957

Query: 120  -------PPPAQQPYQPQPVQPQPHQPMQPQPPVHPM---QPLPPQPPLPP-MFPMQPLP 168
                   PPPA +P          H P    PP+  M   QPLP  P  PP +   Q LP
Sbjct: 958  SMNANLPPPPALKPLSSLSTH---HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014

Query: 169  P 169
            P
Sbjct: 1015 P 1015



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 44/143 (30%), Positives = 50/143 (34%), Gaps = 39/143 (27%)

Query: 62  HHQIIPVLSQQHPPTHTLQPHH--HIPVVP----AQQPVIPQQPMMPVPGQHSMTPIQHH 115
           H Q  P L  Q PP+    PH   H P+ P    A QP  P     P+ GQ    P   H
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---H 855

Query: 116 QPNLPPPAQQPYQPQP--VQPQ----------------PHQPMQ----------PQPPVH 147
                P  Q P  PQP  + PQ                PH  +Q           QPP  
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915

Query: 148 PMQPLPPQPPLPPMFPMQPLPPM 170
             QPLPP P   P     P  P+
Sbjct: 916 --QPLPPAPLAMPHIKPPPTTPI 936



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 9/90 (10%)

Query: 73   HPPTHTLQPHHH-IPVVPAQQPVIPQ-QPMMPVPGQHSMTPIQHHQPNLPPPAQQPY--- 127
            HPP   L P    +P  PAQ P + Q Q + P P  H  T +    P  PP AQ P+   
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ-PPFAQHPFVPG 1042

Query: 128  QPQPVQPQPHQPMQPQPPVHPMQPLPPQPP 157
             P P+ P P  P    PP  P      QPP
Sbjct: 1043 GPPPITP-PTCPSTSTPPAGP--GTSAQPP 1069



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 18/125 (14%)

Query: 47  PPYPSYGYEPMGGWLHHQIIPVLSQ--QHPPTHTLQ-PHHHIPVVPAQQPVIPQQPMMPV 103
           P  P+ G  P    +  Q  P  SQ    P   T   PH HI   PA  P   Q+P  P 
Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP---QRPPSPH 815

Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ-------PLPPQP 156
           P  H  +P    QP L   A QP  P   QP  H    P P  H +Q       P PPQP
Sbjct: 816 PPPHP-SPHPPLQP-LTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQAGPLLQHPGPPQP 871

Query: 157 -PLPP 160
             LPP
Sbjct: 872 FGLPP 876



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 37/175 (21%)

Query: 20  PPHPG-HPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW-----LHHQIIPVLSQQH 73
           PPHP  HP         L PL      +P  PS+   P+ G         Q  P+L    
Sbjct: 817 PPHPSPHPP--------LQPLTGSAG-QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP-----IQHHQPNLPPPAQQPYQ 128
           PP    QP    P     Q  +   P    P      P     +Q  Q    PP +QP  
Sbjct: 868 PP----QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ----PPREQPLP 919

Query: 129 PQP-----VQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQ---PLPPMLPDLT 175
           P P     ++P P  P+ PQ P       PP    P  F M    P PP L  L+
Sbjct: 920 PAPLAMPHIKPPPTTPI-PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLS 973


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 12/137 (8%)

Query: 38  PLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQ 97
           P   Y  + PP P+     +   L   ++P       P   + P    PV+P   P    
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP----PVMPPSLPTSVP 574

Query: 98  QPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL---PP 154
            P MP P   S  P     P LPPP+     P PV P P       PPV P+ PL    P
Sbjct: 575 PPGMP-PSLSSAGP----PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP 629

Query: 155 QPPLPPMFPMQPLPPML 171
            P +PP    Q +PP L
Sbjct: 630 PPGIPPPGVPQGIPPQL 646



 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 19/134 (14%)

Query: 44  SIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPV 103
           S+ PP+  Y   P          P L    PP   L P    PV+P   P     P MP 
Sbjct: 515 SMPPPFVPYSQMP----------PPLPTMPPPV--LPPSLPPPVMPPALPATVPPPGMPP 562

Query: 104 PGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPL-----PPQPPL 158
           P      P     P +PP       P PV P P       PPV P   L     PP  PL
Sbjct: 563 PVMPPSLPTSVPPPGMPPSLSSA-GPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPL 621

Query: 159 PPMFPMQPLPPMLP 172
           PP+    P PP +P
Sbjct: 622 PPLSSATP-PPGIP 634



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 34/124 (27%)

Query: 79  LQPHHHIPVVPAQQPVI-----------PQQPMMPVPG--------QHSMTPIQHHQPNL 119
           LQPHH +P  P   P +           P  PM P PG        Q     + HHQ + 
Sbjct: 76  LQPHH-LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134

Query: 120 PP-----PAQQPYQPQPVQPQPHQPMQ------PQPPVHPMQPLPPQPPLPPMFPMQPLP 168
           PP       + P +  PV P  + P        PQPP     P   QP LP   P QP P
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP---PAQPSP 191

Query: 169 PMLP 172
              P
Sbjct: 192 SQSP 195



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 45/164 (27%), Positives = 57/164 (34%), Gaps = 31/164 (18%)

Query: 20  PPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTL 79
           P  P   G+++F  + L  L+  Q +                  Q+  VL   H P   L
Sbjct: 42  PAAPSSSGFMSFREQHLAQLQQLQQMH---------------QKQMQCVLQPHHLPPPPL 86

Query: 80  QPHHHIPVVPAQ-----QPVIPQQPMMPVPG------QHSMTPIQHHQPNLPPPAQQPYQ 128
            P    PV+P       QP  P  P  P P       Q     + HHQ + PP       
Sbjct: 87  PPP---PVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMEL 143

Query: 129 PQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172
             P +  P  P    PP     P PPQPP P  +P     P LP
Sbjct: 144 ESPPESPPVPPGSYMPPSQSYMP-PPQPP-PSYYPPTSSQPYLP 185



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 15/94 (15%)

Query: 86  PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP 145
           P VP  Q + P  P MP P    + P     P+LPPP   P  P  V P    P  P P 
Sbjct: 519 PFVPYSQ-MPPPLPTMPPP----VLP-----PSLPPPVMPPALPATVPP----PGMPPPV 564

Query: 146 VHPMQPLPPQPP-LPPMFPMQPLPPMLPDLTLEA 178
           + P  P    PP +PP       PP+LP  +L +
Sbjct: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSS 598



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 117 PNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTL 176
           P +PPP   P  P PV P P  P    PP      +PP P +PP  P    PP +P    
Sbjct: 531 PTMPPPVLPPSLPPPVMP-PALPATVPPP-----GMPP-PVMPPSLPTSVPPPGMPPSLS 583

Query: 177 EAWP 180
            A P
Sbjct: 584 SAGP 587



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 9/86 (10%)

Query: 103  VPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPP--------VHPMQPLPP 154
            +P Q S       +P + PP      P P+   P   ++P  P          P  P+PP
Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548

Query: 155  QPPLPPMFPMQP-LPPMLPDLTLEAW 179
             PP PP+ P  P + P    +  E W
Sbjct: 1549 PPPPPPLPPPPPVIKPQTSAVEQERW 1574



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 40/166 (24%), Positives = 56/166 (33%), Gaps = 24/166 (14%)

Query: 26  PGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHI 85
           P Y + S    + L   QS  P   +    P  G    Q++       PP +        
Sbjct: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264

Query: 86  PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQ---------------PNLPPPAQQPY--- 127
               A+     QQ   P P   +MTP +  Q                +LP   + P    
Sbjct: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324

Query: 128 -QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172
             P+PV+ +   P   Q P  P    PP PP     P + +PP LP
Sbjct: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPP-----PNEEVPPPLP 365



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 32/98 (32%), Positives = 39/98 (39%), Gaps = 20/98 (20%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P LS   PP   L P       P+     P  P+MP+P   S TP     P +PPP    
Sbjct: 594 PSLSSAGPPP-VLPP-------PSLSSTAPP-PVMPLPPLSSATP----PPGIPPPG--- 637

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLP-PQPPLPPMFP 163
             PQ + PQ      P PP    Q    P+ P P + P
Sbjct: 638 -VPQGIPPQ--LTAAPVPPASSSQSSQVPEKPRPALLP 672



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 17/46 (36%), Positives = 18/46 (39%), Gaps = 3/46 (6%)

Query: 127 YQPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPPMLP 172
           Y      P P  P    PP  P     P P LPP  P   +PP LP
Sbjct: 510 YMGNMSMPPPFVPYSQMPPPLPTM---PPPVLPPSLPPPVMPPALP 552



 Score = 31.2 bits (69), Expect = 0.57
 Identities = 34/105 (32%), Positives = 43/105 (40%), Gaps = 23/105 (21%)

Query: 82  HHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPNLPPPA-------QQPYQPQPVQ 133
           H+  P VP   PV +P+    P PG  S T      P  P  +       Q   Q Q +Q
Sbjct: 13  HYPPPPVPPPPPVALPEAS--PGPGYSSSTT-----PAAPSSSGFMSFREQHLAQLQQLQ 65

Query: 134 PQPHQPMQPQPPVHPMQPLPPQPPLPPMFP------MQPLPPMLP 172
               + MQ     H + P PP PP PP+ P       QP PP +P
Sbjct: 66  QMHQKQMQCVLQPHHLPP-PPLPP-PPVMPGGGYGDWQPPPPPMP 108



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 24/83 (28%), Positives = 28/83 (33%), Gaps = 4/83 (4%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVP----GQHSMTPIQHHQPNLPPPAQQPYQP 129
           PP  +  P   IP     Q + PQ    PVP     Q S  P +     LP P      P
Sbjct: 622 PPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP 681

Query: 130 QPVQPQPHQPMQPQPPVHPMQPL 152
                 P Q   P   V+   PL
Sbjct: 682 PTTYHPPLQSAGPSEQVNSKAPL 704



 Score = 30.8 bits (68), Expect = 0.74
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%)

Query: 136  PHQPMQPQPPVHPMQPLPPQPPLPPMFPMQPLPP 169
            P  P+ P PPVH    +PP  P+P   P    PP
Sbjct: 1603 PSAPVLPPPPVH--SSIPPPGPVPMGMPPMSKPP 1634



 Score = 30.4 bits (67), Expect = 0.97
 Identities = 39/174 (22%), Positives = 59/174 (33%), Gaps = 48/174 (27%)

Query: 18  PLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGW----LHHQ------IIP 67
           PLPP P  PG     ++   P        PP P+  Y+    +    LHHQ      ++P
Sbjct: 85  PLPPPPVMPGGGYGDWQPPPP----PMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140

Query: 68  VLSQQHPPTHTLQPHHHIPVV----------PAQQPVIPQQPMMPV---------PGQHS 108
           +  +  P +  + P  ++P            P+  P    QP +P          P Q  
Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200

Query: 109 MTP--------------IQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHP 148
           + P              + H Q  LP     P +P     +  Q + P PP  P
Sbjct: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSK-SQLLAPPPPSAP 253



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 6/82 (7%)

Query: 60  WLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPV-IPQQPMMPVPGQHSMTPIQHHQPN 118
           W    ++ +  QQ    H L  H   PVV    P  + ++  +P   Q   +P    +P 
Sbjct: 297 WYRQHLLSL--QQRTKVH-LPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESP-SSEEPP 352

Query: 119 LPPPAQQPYQP-QPVQPQPHQP 139
           LPPP ++   P  P +PQ   P
Sbjct: 353 LPPPNEEVPPPLPPEEPQSEDP 374



 Score = 27.7 bits (60), Expect = 6.3
 Identities = 11/30 (36%), Positives = 17/30 (56%)

Query: 138  QPMQPQPPVHPMQPLPPQPPLPPMFPMQPL 167
            +P+  Q      + +P  PPLPP+ P+ PL
Sbjct: 1314 RPLDEQESQFRERDIPSLPPLPPLPPLPPL 1343


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 53.9 bits (128), Expect = 8e-08
 Identities = 47/169 (27%), Positives = 62/169 (36%), Gaps = 29/169 (17%)

Query: 18  PLPPHPGHPGYINFSYEVLTPLKW-----YQSIRPPY----PSYGYEPMGGWLHHQIIPV 68
           PLP  P  P   ++   + T   +     YQS++       PSYG  P            
Sbjct: 415 PLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA---------- 464

Query: 69  LSQQHPPTHTLQPHHHIPVVPAQQPVIPQQ-----PMMPVPGQHSMTPIQHHQPNLPPPA 123
                PP H     H  P  P   PV P       P +P P      P   + PN PPP 
Sbjct: 465 ---YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPP 521

Query: 124 QQPYQPQPVQPQPHQPMQPQPPVHPMQPLPP--QPPLPPMFPMQPLPPM 170
            +      V P P   +   P  +P   +PP  QPP+PP  P   +PP+
Sbjct: 522 PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 21/111 (18%)

Query: 74  PPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQ 133
           PP +   P  H+P  P   P  P  P +P P      P     P +PPP    Y P P  
Sbjct: 462 PPAYG--PPAHLPYHPHVYPPNPPPPPVPPP------PASFPPPAIPPPTPG-YPPPPPT 512

Query: 134 PQPHQPMQPQ--PPVHPMQPLPPQ----------PPLPPMFPMQPLPPMLP 172
             P+ P  P   PP H + P PP           PP  P     P+PP +P
Sbjct: 513 YNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP 563



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 48/151 (31%), Positives = 56/151 (37%), Gaps = 48/151 (31%)

Query: 63  HQIIPVLSQ--QHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP 120
           HQI+ + SQ  Q  P HT    H +   P+ QP  PQ P            +Q  QP+  
Sbjct: 252 HQILDLYSQGKQQMPHHT---PHQLQQPPSLQPT-PQVPQ-----------VQQSQPSQS 296

Query: 121 PPAQQPYQPQPVQP----QP-HQPMQPQP-PVHPMQ-----------------PLPPQ-- 155
               QP Q  P QP    QP  QP +P P P  P Q                 P PP+  
Sbjct: 297 SEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIP 356

Query: 156 ------PPLPPMFPMQPLPPMLPDLTLEAWP 180
                 PPLPP  P     P L     EA P
Sbjct: 357 KIETTHPPLPPAHPPPDRKPPLAAALGEAEP 387



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 15/118 (12%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           PV +   P      P H  PV   Q P +P +P  P P  + MT +      +     Q 
Sbjct: 390 PVDATDLPKVQIPPPAHPAPV--HQPPPLPHRPPPPPPSSY-MTGMSTTSSYMSGEGYQS 446

Query: 127 YQPQPVQPQPHQPMQPQ---PPVH---------PMQPLPPQPPLPPMFPMQPLPPMLP 172
            Q       P     P    PP H         P  P PP PP P  FP   +PP  P
Sbjct: 447 LQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP 504



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 37/140 (26%), Positives = 48/140 (34%), Gaps = 45/140 (32%)

Query: 66  IPVLSQQHPP--THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHS--------------- 108
           +P + Q  P   +   QP    P  PAQQ    QQP  P P   S               
Sbjct: 285 VPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEE 344

Query: 109 ----------MTPIQHHQPNLPPPAQQPYQPQPV-----QPQPHQPMQ---------PQP 144
                     +  I+   P LPP    P +  P+     + +P  P+          P P
Sbjct: 345 NKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPP 404

Query: 145 ----PVHPMQPLPPQPPLPP 160
               PVH   PLP +PP PP
Sbjct: 405 AHPAPVHQPPPLPHRPPPPP 424


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 36/89 (40%), Positives = 41/89 (46%), Gaps = 9/89 (10%)

Query: 99  PMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQP--PVHPMQPLPPQP 156
           P    PG  S+  +   Q   P   QQP QPQP Q QP QP QPQP  P  P QP   Q 
Sbjct: 348 PAFSSPGGLSLGNVTAWQQ--PQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQS 405

Query: 157 PLPP-----MFPMQPLPPMLPDLTLEAWP 180
            L P     + P  PLP +   LT+   P
Sbjct: 406 HLVPVSLSNLIPGSPLPHVGAALTVTTHP 434



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 71  QQHPPTHTLQPHHHIPVVPAQ-QPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPY-- 127
           QQ       QP    P  P Q QP  PQQP  P   Q  + P+     NL P +  P+  
Sbjct: 368 QQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVS--LSNLIPGSPLPHVG 425

Query: 128 QPQPVQPQPHQPMQPQPPVHPMQPLPPQPPLPPMFP 163
               V   PH  ++ + PV P +   P PP P +FP
Sbjct: 426 AALTVTTHPHISIKSE-PVSPSRERSPAPPPPAVFP 460


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 58/189 (30%), Positives = 64/189 (33%), Gaps = 44/189 (23%)

Query: 19   LPPHPGHPGYINFSYEVLTPLKWYQSIRPPYPSYGYEPMGGWLH-HQIIPVLSQQHPPTH 77
            LPP P  P           PL    SI PP  S    P+G   H H   PV   QH   +
Sbjct: 1290 LPPPPQQP----------PPLPQLGSIPPPPASA--PPVGPHRHFHAHGPVPGPQH---Y 1334

Query: 78   TL-----------------QPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTP---IQHHQP 117
            TL                  PH   P+     P+    P    P  H   P   I  H P
Sbjct: 1335 TLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHP 1394

Query: 118  NLPPPAQQPYQPQPVQP-----QPHQPMQPQPPVHPMQPLPPQPPLP---PMFPMQPLPP 169
             + P A     P    P      PH P  P  P  P+ P P  PPLP   P  P  PLPP
Sbjct: 1395 QMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPP 1454

Query: 170  MLPDLTLEA 178
              P   L A
Sbjct: 1455 TSPHGPLHA 1463



 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 45/154 (29%), Positives = 54/154 (35%), Gaps = 30/154 (19%)

Query: 47   PPYPSYGYEPMGGWLHHQIIPVL----SQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMP 102
            P +  +G  P    LH    P+     + QHPP H   P H I     Q        MMP
Sbjct: 1351 PQFAPHGRHP----LHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQ--------MMP 1398

Query: 103  VPGQHSMTPIQHHQPNLPPPA---QQPYQPQPVQPQPHQPMQPQP---PVHPMQPLPPQP 156
              G           P   PP      P+ PQ     PH P+ P P   P+ P  P  P  
Sbjct: 1399 AAGAAG-------GPGSRPPGGSYSHPHHPQSPL-SPHSPIPPHPSYPPLPPPSPHTPHS 1450

Query: 157  PLPPMFPMQPLPPMLPDLTLEAWPSTDKTKREEV 190
            PLPP  P  PL    P  T     +  K K   +
Sbjct: 1451 PLPPTSPHGPLHASGPPGTANPPSANPKAKPSRI 1484



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 9/89 (10%)

Query: 76   THTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQ 135
            TH    HHH         V+P        GQ  +  +       P PA  PY P P QP 
Sbjct: 1238 THHHHHHHHHGHSHGGLGVLPD-------GQSKLQALHAQYCQGPGPAPPPYLP-PQQPS 1289

Query: 136  PHQPMQPQPPVHPMQPLPPQP-PLPPMFP 163
               P Q  PP+  +  +PP P   PP+ P
Sbjct: 1290 LPPPPQQPPPLPQLGSIPPPPASAPPVGP 1318



 Score = 27.7 bits (60), Expect = 6.3
 Identities = 11/25 (44%), Positives = 14/25 (56%)

Query: 134  PQPHQPMQPQPPVHPMQPLPPQPPL 158
            P+PHQ M P PP  P +    Q P+
Sbjct: 1174 PRPHQRMPPPPPPPPPEEYKSQRPV 1198


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 36/113 (31%), Positives = 44/113 (38%), Gaps = 15/113 (13%)

Query: 67  PVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQP 126
           P+ S   P    + P      V A   + P  P+ P PG   + P        PPP   P
Sbjct: 650 PITSADCPKPMVVTPG--AAAVAAPSVLAPTLPLPPPPGFPPLPP--------PPPPPPP 699

Query: 127 YQPQPVQPQPHQPMQPQPPVHPM-----QPLPPQPPLPPMFPMQPLPPMLPDL 174
               P+ P    P  P PP HP       PLP  P +PP   + PLPP  P L
Sbjct: 700 QPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGL 752



 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 34/91 (37%), Positives = 40/91 (43%), Gaps = 13/91 (14%)

Query: 75  PTHTLQPHHHIPVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQP 134
           PT  L P    P +P   P  P QP  P+P      P+    P  PPP   P    P  P
Sbjct: 677 PTLPLPPPPGFPPLPPPPPPPPPQPGFPMP-----PPLPPPPP--PPPPAHPAVTVPPPP 729

Query: 135 QPHQPMQPQPPVHPMQPLPPQPPLPP-MFPM 164
            P  P  P PP+     LPP PP PP +FP+
Sbjct: 730 LPAPPGVPPPPI-----LPPLPPFPPGLFPV 755



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 33/97 (34%), Positives = 40/97 (41%), Gaps = 19/97 (19%)

Query: 86  PVVPAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLP--PPAQQPYQPQPVQPQPHQPMQPQ 143
           P+  A  P    +PM+  PG  ++       P LP  PP   P  P P  P P QP  P 
Sbjct: 650 PITSADCP----KPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM 705

Query: 144 PPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWP 180
           PP        P PP PP     P PP  P +T+   P
Sbjct: 706 PP--------PLPPPPP-----PPPPAHPAVTVPPPP 729



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 17/99 (17%)

Query: 89   PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQ--PHQPMQPQPPV 146
            PA     P++P +   G   ++P         PPA++     P+ P+  P   ++ +P  
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSP--------EPPAKEVEARPPLSPERAPEHDLEVEPEP 1270

Query: 147  HPMQPLPPQPPLPP----MFPMQPLPPMLPDLTLEAWPS 181
              M PLP QPPLPP         P PP  P+ T  + PS
Sbjct: 1271 PMMLPLPLQPPLPPPRPPR---PPSPPPEPETTDASHPS 1306



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 4/83 (4%)

Query: 96   PQQPMMPVPGQHSMTPIQHHQPNLP----PPAQQPYQPQPVQPQPHQPMQPQPPVHPMQP 151
            P+ P   V  +  ++P +  + +L     PP   P   QP  P P  P  P PP  P   
Sbjct: 1241 PEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETT 1300

Query: 152  LPPQPPLPPMFPMQPLPPMLPDL 174
                P +PP    +  PP  P L
Sbjct: 1301 DASHPSVPPEPLAEDHPPHTPGL 1323



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 28/122 (22%)

Query: 86   PVVPAQQPVIPQQPMMPVPGQHSMTP---IQHHQPNLPPPAQQ---------PYQPQ-PV 132
            P++PA     P  PM   PG+   +P   +    P + PPA           P QPQ PV
Sbjct: 1459 PLLPAPLASCPP-PMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV 1517

Query: 133  QPQPHQPMQ------------PQPPVHPMQPLPPQPPL--PPMFPMQPLPPMLPDLTLEA 178
             P  H P              P PP+ P  P PP PP   P   P + L    P   +  
Sbjct: 1518 FPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577

Query: 179  WP 180
             P
Sbjct: 1578 GP 1579



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 96  PQQPMMPVPG-QHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQ--PQPPVHPMQPL 152
           P     P PG + + +P Q    + PPP ++P        +     +  P PP     PL
Sbjct: 383 PPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPP-----PL 437

Query: 153 PPQPPLPPMFPMQPLPPMLPD 173
           PP  PL    P  P  P  PD
Sbjct: 438 PPAEPLAKEKPGTPPGPPPPD 458


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.487 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,746,505
Number of Sequences: 37866
Number of extensions: 974642
Number of successful extensions: 29027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 875
Number of HSP's successfully gapped in prelim test: 968
Number of HSP's that attempted gapping in prelim test: 7683
Number of HSP's gapped (non-prelim): 9617
length of query: 191
length of database: 18,247,518
effective HSP length: 96
effective length of query: 95
effective length of database: 14,612,382
effective search space: 1388176290
effective search space used: 1388176290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press