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Search of human proteins with 32171221
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32171221 GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein [Homo sapiens]
(395 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso... 803 0.0
gi|47933392 cytohesin 1 interacting protein [Homo sapiens] 186 2e-47
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 63 4e-10
gi|45120119 microtubule associated serine/threonine kinase 1 [Ho... 55 8e-08
gi|46249382 paired-like homeobox 2a [Homo sapiens] 54 2e-07
gi|148727255 microtubule associated serine/threonine kinase fami... 54 2e-07
gi|21361142 PDZ domain containing 1 [Homo sapiens] 53 4e-07
gi|112363080 microtubule associated serine/threonine kinase 2 [H... 52 9e-07
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 51 2e-06
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor... 51 2e-06
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 50 3e-06
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 50 3e-06
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 50 3e-06
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 50 3e-06
gi|168229174 RNA binding motif protein 27 [Homo sapiens] 49 8e-06
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 49 1e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 49 1e-05
gi|62945417 dystrophia myotonica-containing WD repeat motif prot... 48 2e-05
gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2 ... 47 2e-05
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 47 2e-05
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s... 47 2e-05
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 47 2e-05
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 47 3e-05
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 47 4e-05
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 47 4e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 4e-05
gi|22027541 programmed cell death 7 [Homo sapiens] 47 4e-05
gi|4759306 lin-7 homolog A [Homo sapiens] 46 5e-05
gi|9966877 golgi associated PDZ and coiled-coil motif containing... 46 5e-05
gi|62868213 golgi associated PDZ and coiled-coil motif containin... 46 5e-05
>gi|32171221 GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein [Homo sapiens]
Length = 395
Score = 803 bits (2074), Expect = 0.0
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MTLRRLRKLQQKEEAAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGPPADELYAALE 60
MTLRRLRKLQQKEEAAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGPPADELYAALE
Sbjct: 1 MTLRRLRKLQQKEEAAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGPPADELYAALE 60
Query: 61 DYHPAELYRALAVSGGTLPRRKGSGFRWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYG 120
DYHPAELYRALAVSGGTLPRRKGSGFRWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYG
Sbjct: 61 DYHPAELYRALAVSGGTLPRRKGSGFRWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYG 120
Query: 121 LHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGN 180
LHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGN
Sbjct: 121 LHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGN 180
Query: 181 VLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTL 240
VLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTL
Sbjct: 181 VLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTL 240
Query: 241 ESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPP 300
ESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPP
Sbjct: 241 ESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPP 300
Query: 301 PPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQAL 360
PPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQAL
Sbjct: 301 PPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQAL 360
Query: 361 CGPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL 395
CGPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL
Sbjct: 361 CGPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL 395
>gi|47933392 cytohesin 1 interacting protein [Homo sapiens]
Length = 359
Score = 186 bits (473), Expect = 2e-47
Identities = 129/333 (38%), Positives = 186/333 (55%), Gaps = 28/333 (8%)
Query: 71 LAVSGGTLPR-RKGSGF-RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQR 128
LA + TLPR RK R +LS QRK++T+EK+DN+TFGFEIQ+Y ++
Sbjct: 45 LADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACS 104
Query: 129 VEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLY 188
EM T +C++ E SPA AGL GD +A++NG++ EG ++++VD+I++SGN+L +ETL
Sbjct: 105 SEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLN 164
Query: 189 GTSI-RKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCL 247
GT I ++ ELEA+LQ LKQTL +KW EYRSL +QE RL+HG PS+ + ++ L
Sbjct: 165 GTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSL-ENMDLDELSL 223
Query: 248 YGAGLLPGSLPFGPLLAVPGR------PRGGARRARGDADDAVYHTCFFGDSEPPALPPP 301
+G LPG GP L R + D++D Y TC DS A
Sbjct: 224 FGP--LPGP---GPALVDRNRLSSESSCKSWLSSMTMDSEDG-YQTCVSEDSSRGAF--- 274
Query: 302 PPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQALC 361
+ P G R++ R+ S+ G+ LW E ++
Sbjct: 275 --SRQTSTDDECFIPKEGDDFLRRSSSRRNRSI------SNTSSGSMSPLW-EGNLSSMF 325
Query: 362 GPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQ 394
G RK++ S R++LLKFIPGL+R++EEEES+
Sbjct: 326 GTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESR 358
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 63.2 bits (152), Expect = 4e-10
Identities = 63/229 (27%), Positives = 97/229 (42%), Gaps = 13/229 (5%)
Query: 112 FGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREI 171
+GF ++ ++ + + V V + SPAQ AGL GD I +NG +V G+ H ++
Sbjct: 960 YGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDV 1019
Query: 172 VDIIKASGNVLRLET--LYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQR-LVHG 228
V+++ SGN + L T L TSI+ AR K + + R Q++R +
Sbjct: 1020 VELLLKSGNKISLRTTALENTSIKVG--PARKNVAKGRMARRSKRSRRRETQDRRKSLFK 1077
Query: 229 LVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTC 288
+ K S+ T S S L+ + SLP P ++ P R A D T
Sbjct: 1078 KISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSP---TTPCRSPAPDVPADTT 1134
Query: 289 FFGDSEPPALPPPPPPARAFGPGPAE----TPAVGPGPGPRAALSRSAS 333
S P+ P PA A P+ +GP P P+ +S S
Sbjct: 1135 ASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGP-PRPKTGRRKSTS 1182
Score = 33.1 bits (74), Expect = 0.45
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 10 QQKEEAAATPDPAARTPDSEVAPAAPVPTPG-PPAAAATP----GPPADEL 55
++K ++ P P A P S P +P P PG PPA A +P G AD+L
Sbjct: 1177 RRKSTSSIPPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKL 1227
>gi|45120119 microtubule associated serine/threonine kinase 1 [Homo
sapiens]
Length = 1570
Score = 55.5 bits (132), Expect = 8e-08
Identities = 56/219 (25%), Positives = 96/219 (43%), Gaps = 22/219 (10%)
Query: 99 RKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASV 158
R +T+++ + +GF ++ ++ + + V V E PAQ AGL GD I V
Sbjct: 965 RSPITIQRSGKK-YGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHV 1023
Query: 159 NGLNVEGIRHREIVDIIKASGNVLRLET--LYGTSI-----RKAELEARLQYLKQTLYEK 211
NG V G+ H E+V++I SGN + + T TSI R++ +A++ + K
Sbjct: 1024 NGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRPSAK 1083
Query: 212 WGEYRSLMVQEQRLVHGLVVKDPSIYDT---LESVRSCLYGAGLLPGSLPFGPLLAVPGR 268
G+ +++ + + K ++ T L S+ L + LPGS P +P R
Sbjct: 1084 EGQES----KKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGS----PTHGLPAR 1135
Query: 269 PRGGARRARGDADDAVYHTCFFGDSEPPALPPPPPPARA 307
+ R+ D+ Y S P + P P + A
Sbjct: 1136 SPTHSYRS---TPDSAYLGASSQSSSPASSTPNSPASSA 1171
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/109 (34%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
Query: 272 GARRARGDADDAVYHTCFFGDSEPPALPPPPPPARA---FGPGPAETP-AVGPGPGPRAA 327
G R + DD+ TC +LPPPP P A P P GPGPGP
Sbjct: 166 GEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQ 225
Query: 328 LSRSASVRCAGPGGGGGGGAPGALWTEAREQALCGPGLRKTKYRSFRRR 376
+ A GGGGG GA A +A + A GPG SF R+
Sbjct: 226 PLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRK 274
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 54.3 bits (129), Expect = 2e-07
Identities = 72/316 (22%), Positives = 117/316 (37%), Gaps = 26/316 (8%)
Query: 10 QQKEEAAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGPPADELYAALEDYHPAELYR 69
+Q+ E+ + + S A A + PG A + G P P L
Sbjct: 879 RQRLESTEKKKISGKVTKSLSASALSLMIPGDMFAVSPLGSPMS----------PHSLSS 928
Query: 70 ALAVSGGTLPRRKGSGFRWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRV 129
+ S + P R S S SP Q + + +GF I+ ++ +
Sbjct: 929 DPSSSRDSSPSRDSSA-----ASASPHQPIVI----HSSGKNYGFTIRAIRVYVGDSDIY 979
Query: 130 EMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLET--L 187
+ V V E SPA AGL GD I +NG V G+ H E+++++ SGN + + T
Sbjct: 980 TVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPF 1039
Query: 188 YGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCL 247
TSI+ R Y + + + ++ +R + + K PS SCL
Sbjct: 1040 ENTSIKTGPAR-RNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCL 1098
Query: 248 YGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPPPPPPARA 307
+ SLP P ++ R + R+ D + S P+ P PA +
Sbjct: 1099 NRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSS----QSSSPSSSAPNSPAGS 1154
Query: 308 FGPGPAETPAVGPGPG 323
P+ + P G
Sbjct: 1155 GHIRPSTLHGLAPKLG 1170
Score = 29.3 bits (64), Expect = 6.5
Identities = 17/55 (30%), Positives = 21/55 (38%), Gaps = 1/55 (1%)
Query: 293 SEPPALPPPPP-PARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGG 346
+EP + P PP P A + P GP PGP S+ P G G
Sbjct: 1981 AEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKG 2035
>gi|21361142 PDZ domain containing 1 [Homo sapiens]
Length = 519
Score = 53.1 bits (126), Expect = 4e-07
Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 14/95 (14%)
Query: 104 LEKEDNQTFGFEIQTYGLHHREEQRVEMVT---FVCRVHESSPAQLAGLTPGDTIASVNG 160
L K++ Q +GF + R+E T V V + SPA+ AGL GD + +NG
Sbjct: 12 LSKQEGQNYGFFL-----------RIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRING 60
Query: 161 LNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKA 195
+ V+ H ++VD+++ SGN + L L G S KA
Sbjct: 61 VFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKA 95
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/52 (40%), Positives = 31/52 (59%)
Query: 133 TFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
+F+ V + PA LAGL D I VNG+NV + ++VD I++SG + L
Sbjct: 401 SFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTL 452
Score = 38.5 bits (88), Expect = 0.011
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 144 AQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQY 203
A AG+ D + VNG NVE H E+V+ +K SG+ + + L K +E ++Q+
Sbjct: 169 AMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRV-MFLLVDKETDKRHVEQKIQF 227
Query: 204 LKQTLYEKWGEYRSLMVQEQRLVHG 228
++T K ++ +V+ ++ +G
Sbjct: 228 KRETASLKLLPHQPRIVEMKKGSNG 252
Score = 38.5 bits (88), Expect = 0.011
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 8/95 (8%)
Query: 119 YGLHHR--EEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIK 176
YG + R EQ+ +++ + SPA+ AGL D + +VNG +VE + H +V++I+
Sbjct: 253 YGFYLRAGSEQKGQIIK---DIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIR 309
Query: 177 ASG---NVLRLETLYGTSIRKAELEARLQYLKQTL 208
G ++L ++ R A L Y Q L
Sbjct: 310 KGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQEL 344
>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
sapiens]
Length = 1798
Score = 52.0 bits (123), Expect = 9e-07
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 17/208 (8%)
Query: 112 FGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREI 171
+GF ++ ++ + + V V + PA AGL GD I VNG V G+ H E+
Sbjct: 1114 YGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEV 1173
Query: 172 VDIIKASGNVLRLET--LYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGL 229
V++I SGN + + T L TSI+ AR K + + R QE R L
Sbjct: 1174 VELILKSGNKVAISTTPLENTSIKVG--PARKGSYKAKMARRSKRSRGKDGQESRKRSSL 1231
Query: 230 ---VVKDPSIYDT---LESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDA 283
+ K S+ T L S+ L PGS L+ P P G R DA
Sbjct: 1232 FRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLS-PRSPTQGYR----VTPDA 1286
Query: 284 VYHTCFFGDSEPPALPPPPPPARAFGPG 311
V+ G+S + P P+ G G
Sbjct: 1287 VHSV--GGNSSQSSSPSSSVPSSPAGSG 1312
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/69 (44%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 117 QTYGLH-HREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDII 175
Q YG H H E+ R F+ RV SPA+ A L GD + VNG+NVEG H ++V I
Sbjct: 19 QGYGFHLHGEKGRRGQ--FIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRI 76
Query: 176 KASGNVLRL 184
KA RL
Sbjct: 77 KAVEGQTRL 85
Score = 45.8 bits (107), Expect = 7e-05
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 8/96 (8%)
Query: 89 KNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG 148
K++S + R L ++ Q +GF + H ++ R ++ V SPA +G
Sbjct: 138 KDVSGPLRELRPRLCHLRKGPQGYGFNL------HSDKSRPGQ--YIRSVDPGSPAARSG 189
Query: 149 LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
L D + VNG NVEG+RH E+V IKA + RL
Sbjct: 190 LRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARL 225
>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
[Homo sapiens]
Length = 326
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/69 (44%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 117 QTYGLH-HREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDII 175
Q YG H H E+ R F+ RV SPA+ A L GD + VNG+NVEG H ++V I
Sbjct: 19 QGYGFHLHGEKGRRGQ--FIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRI 76
Query: 176 KASGNVLRL 184
KA RL
Sbjct: 77 KAVEGQTRL 85
Score = 45.8 bits (107), Expect = 7e-05
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 8/96 (8%)
Query: 89 KNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG 148
K++S + R L ++ Q +GF + H ++ R ++ V SPA +G
Sbjct: 138 KDVSGPLRELRPRLCHLRKGPQGYGFNL------HSDKSRPGQ--YIRSVDPGSPAARSG 189
Query: 149 LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
L D + VNG NVEG+RH E+V IKA + RL
Sbjct: 190 LRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARL 225
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 87 RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQL 146
RW +S SPE++ ++ L+K+ GF+I + + R+++ F+ V PA L
Sbjct: 1080 RWSIVS-SPEREITLVNLKKDAKYGLGFQI----IGGEKMGRLDLGIFISSVAPGGPADL 1134
Query: 147 AG-LTPGDTIASVNGLNVEGIRHREIVDIIK 176
G L PGD + SVN +++EG+ H ++I++
Sbjct: 1135 DGCLKPGDRLISVNSVSLEGVSHHAAIEILQ 1165
Score = 33.9 bits (76), Expect = 0.26
Identities = 12/33 (36%), Positives = 24/33 (72%)
Query: 152 GDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
GD + +VNG+++EG H++ V+ ++ +G V+ L
Sbjct: 1420 GDRVLAVNGVSLEGATHKQAVETLRNTGQVVHL 1452
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 87 RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQL 146
RW +S SPE++ ++ L+K+ GF+I + + R+++ F+ V PA L
Sbjct: 889 RWSIVS-SPEREITLVNLKKDAKYGLGFQI----IGGEKMGRLDLGIFISSVAPGGPADL 943
Query: 147 AG-LTPGDTIASVNGLNVEGIRHREIVDIIK 176
G L PGD + SVN +++EG+ H ++I++
Sbjct: 944 DGCLKPGDRLISVNSVSLEGVSHHAAIEILQ 974
Score = 33.9 bits (76), Expect = 0.26
Identities = 12/33 (36%), Positives = 24/33 (72%)
Query: 152 GDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
GD + +VNG+++EG H++ V+ ++ +G V+ L
Sbjct: 1224 GDRVLAVNGVSLEGATHKQAVETLRNTGQVVHL 1256
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 87 RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQL 146
RW +S SPE++ ++ L+K+ GF+I + + R+++ F+ V PA L
Sbjct: 1080 RWSIVS-SPEREITLVNLKKDAKYGLGFQI----IGGEKMGRLDLGIFISSVAPGGPADL 1134
Query: 147 AG-LTPGDTIASVNGLNVEGIRHREIVDIIK 176
G L PGD + SVN +++EG+ H ++I++
Sbjct: 1135 DGCLKPGDRLISVNSVSLEGVSHHAAIEILQ 1165
Score = 33.9 bits (76), Expect = 0.26
Identities = 12/33 (36%), Positives = 24/33 (72%)
Query: 152 GDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
GD + +VNG+++EG H++ V+ ++ +G V+ L
Sbjct: 1415 GDRVLAVNGVSLEGATHKQAVETLRNTGQVVHL 1447
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 87 RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQL 146
RW +S SPE++ ++ L+K+ GF+I + + R+++ F+ V PA L
Sbjct: 1061 RWSIVS-SPEREITLVNLKKDAKYGLGFQI----IGGEKMGRLDLGIFISSVAPGGPADL 1115
Query: 147 AG-LTPGDTIASVNGLNVEGIRHREIVDIIK 176
G L PGD + SVN +++EG+ H ++I++
Sbjct: 1116 DGCLKPGDRLISVNSVSLEGVSHHAAIEILQ 1146
Score = 33.9 bits (76), Expect = 0.26
Identities = 12/33 (36%), Positives = 24/33 (72%)
Query: 152 GDTIASVNGLNVEGIRHREIVDIIKASGNVLRL 184
GD + +VNG+++EG H++ V+ ++ +G V+ L
Sbjct: 1396 GDRVLAVNGVSLEGATHKQAVETLRNTGQVVHL 1428
>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
Length = 1060
Score = 48.9 bits (115), Expect = 8e-06
Identities = 24/52 (46%), Positives = 24/52 (46%), Gaps = 13/52 (25%)
Query: 295 PPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGG 346
PP LPPPPPP P P P GPGPGP GPG G G G
Sbjct: 320 PPGLPPPPPPGMLMPPMPGPGPGPGPGPGP-------------GPGPGPGPG 358
Score = 34.7 bits (78), Expect = 0.15
Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 295 PPALP-PPPPPA----------RAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGG 343
P +P PPPPP PGP P GPGPGP S+R P G G
Sbjct: 311 PSMIPFPPPPPGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHG 370
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/72 (41%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 299 PPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQ 358
PPP PP A G G A GP PGP A R GPGGGG GG G+ ++
Sbjct: 9 PPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG----GGPGGGGPGG--GSAGGPSQPP 62
Query: 359 ALCGPGLRKTKY 370
GPG+RK +
Sbjct: 63 GGGGPGIRKDAF 74
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
Length = 2161
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 98 QRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVC-----RVHESSPAQLAGLTPG 152
+ K + L+K+D++ FGF ++ E+ F V E A AGL G
Sbjct: 660 KEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMG 719
Query: 153 DTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGT 190
D + VNG NV + HR++V++I+ GN L ++ + T
Sbjct: 720 DFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVT 757
Score = 36.6 bits (83), Expect = 0.041
Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 16/75 (21%)
Query: 291 GDSEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSAS---------------VR 335
GD PP P P PA A P P P G G SRS+S +
Sbjct: 1643 GDPHPPGPPAPAAPAPA-APQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS 1701
Query: 336 CAGPGGGGGGGAPGA 350
G G GGGG GA
Sbjct: 1702 AEGGGSAGGGGGAGA 1716
Score = 35.4 bits (80), Expect = 0.090
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 292 DSEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349
+ E P PPP A GP P+ G GP P + S G GGGGG + G
Sbjct: 1025 EMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPG---APSPSHHGSAGGGGGSSQG 1079
Score = 31.6 bits (70), Expect = 1.3
Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 11 QKEEAAATPDPAARTPDSEVAPAAPVP-TPGPPAAAATP 48
+K E+ TP P PD+ APA P+P P P AAA P
Sbjct: 1578 EKPESPLTPGPPHPLPDTP-APATPLPPVPPPAVAAAPP 1615
Score = 30.4 bits (67), Expect = 2.9
Identities = 23/56 (41%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
Query: 297 ALPPPPPPARAFGPGPAETPAVGP--GPGPRAALSRSASVRCAGPGGGGGGGAPGA 350
A PP P A P P E G P PR AL S+R G GGG PGA
Sbjct: 1008 APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLR--GWRGGGPSPTPGA 1061
>gi|62945417 dystrophia myotonica-containing WD repeat motif protein
[Homo sapiens]
Length = 674
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/59 (45%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 295 PPALPPPPP-PARAFGPGPA----ETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAP 348
PP P PPP PA A GPG A P GPGPGP R + VR P G G P
Sbjct: 55 PPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
Score = 37.7 bits (86), Expect = 0.018
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 19/105 (18%)
Query: 255 GSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPPPPPPARAFGPG-PA 313
G P PL P+ G+ R + C + +E P PP PG P
Sbjct: 414 GGAPLSPL------PKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPG 467
Query: 314 ETPAV---------GPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349
TP GPGP PR +LSRS S+ P GGG G PG
Sbjct: 468 TTPPAASSSRGGEPGPGPLPR-SLSRSNSL--PHPAGGGKAGGPG 509
Score = 28.9 bits (63), Expect = 8.5
Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 298 LPPPPPPARAFGPGPAETPA----VGPGPGPRAALSRSASVRCAGPGGGGGGGAP 348
L P AR GP A+TP P PGP +A A+ + P G G P
Sbjct: 35 LLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGP 89
>gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2
[Homo sapiens]
Length = 281
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 98 QRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVC-----RVHESSPAQLAGLTPG 152
+ K + L+K+DN+ FGF ++ E+ F V E A AGL G
Sbjct: 35 EEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTG 94
Query: 153 DTIASVNGLNVEGIRHREIVDIIKASGNVLRLETL 187
D + VN NV + HR++V++I+ GN L L+ +
Sbjct: 95 DFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVV 129
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo
sapiens]
Length = 1747
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/308 (22%), Positives = 103/308 (33%), Gaps = 66/308 (21%)
Query: 100 KVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVC-----RVHESSPAQLAGLTPGDT 154
KV L+K D++ FGF ++ E+ F V A AGL GD
Sbjct: 586 KVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDF 645
Query: 155 IASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGT------------------------ 190
+ VNG+NV + H+++V +I+ GN L ++ + T
Sbjct: 646 LIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDGARRRAPPPPKRAPSTTL 705
Query: 191 SIRKAELEARLQYLKQTLYEKWGEYRSLM-----------VQEQRLVHGLVVKDPSIYDT 239
++R + A L+ L K + ++ + + V + P+
Sbjct: 706 TLRSKSMTAELEELASIRRRKGEKLDEMLAAAAEPTLRPDIADADSRAATVKQRPTSRRI 765
Query: 240 LESVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFG-------- 291
+ S L+ LPG +PG R G R + +D + G
Sbjct: 766 TPAEISSLFERQGLPGP------EKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSM 819
Query: 292 ----------DSEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGG 341
P PPPPP F GP PA P P P A S G
Sbjct: 820 QDPVREGRGIPPPPQTAPPPPPAPYYFDSGP--PPAFSPPPPPGRAYDTVRSSFKPGLEA 877
Query: 342 GGGGGAPG 349
G GA G
Sbjct: 878 RLGAGAAG 885
>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
sapiens]
Length = 358
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 119 YGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKAS 178
YG H E+ ++ ++ V SPA+ AGL GD + VNG NVE H+++V I+A+
Sbjct: 24 YGFHLHGEKG-KLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAA 82
Query: 179 GNVLRL 184
N +RL
Sbjct: 83 LNAVRL 88
Score = 43.1 bits (100), Expect = 4e-04
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 17/144 (11%)
Query: 50 PPADELYAALEDYHPAELYRALAVSGGTLP------RRKGSGFRWKNLSQSPEQQRKV-- 101
P DE L EL RA G P + G+ + +S +QR++
Sbjct: 93 PETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRP 152
Query: 102 -LTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNG 160
L K+ +GF + H ++ + F+ V SPA+ +GL D I VNG
Sbjct: 153 RLCTMKKGPSGYGFNL------HSDKSKPGQ--FIRSVDPDSPAEASGLRAQDRIVEVNG 204
Query: 161 LNVEGIRHREIVDIIKASGNVLRL 184
+ +EG +H ++V I+A G+ +L
Sbjct: 205 VCMEGKQHGDVVSAIRAGGDETKL 228
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 98 QRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVC-----RVHESSPAQLAGLTPG 152
+ K + L+K+DN+ FGF ++ E+ F V E A AGL G
Sbjct: 623 EEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTG 682
Query: 153 DTIASVNGLNVEGIRHREIVDIIKASGNVLRLETL 187
D + VN NV + HR++V++I+ GN L L+ +
Sbjct: 683 DFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVV 717
>gi|223890252 glutamate receptor interacting protein 1 [Homo
sapiens]
Length = 1076
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 102 LTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG-LTPGDTIASVNG 160
+TL KE N TFGF I+ G H + + V C V PA G + PGD + SV+G
Sbjct: 153 VTLHKEGN-TFGFVIR--GGAHDDRNKSRPVVITC-VRPGGPADREGTIKPGDRLLSVDG 208
Query: 161 LNVEGIRHREIVDIIKASGNVLRLETLYGTSI 192
+ + G H E + I+K G L Y S+
Sbjct: 209 IRLLGTTHAEAMSILKQCGQEAALLIEYDVSV 240
Score = 35.0 bits (79), Expect = 0.12
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 149 LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLY 188
L GD I +VNG+N+ RH EI+ ++K G + LE Y
Sbjct: 95 LDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEVEY 134
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/83 (38%), Positives = 34/83 (40%), Gaps = 12/83 (14%)
Query: 291 GDSEPPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGP------GGGGG 344
G PPA PPPPP PGP P + P P AA A P GGGG
Sbjct: 161 GPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGG 220
Query: 345 GGAPGALWTEAREQALCGPGLRK 367
GAPG A+ G LRK
Sbjct: 221 AGAPGL------AAAIAGAKLRK 237
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 46.6 bits (109), Expect = 4e-05
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 284 VYHTCFFGDSEPPALPPPPPPARAFGPGPAETPAVGPG---PGPRAALSRSASVRCAGPG 340
+Y C + PPA PPPPP PA PA GP P RA++ R + AGP
Sbjct: 893 MYSCCSAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPP 952
Query: 341 GGGG 344
GG G
Sbjct: 953 GGAG 956
Score = 35.4 bits (80), Expect = 0.090
Identities = 21/50 (42%), Positives = 22/50 (44%), Gaps = 12/50 (24%)
Query: 301 PPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGA 350
PP PAR P P +GPG G AG GG GGGAP A
Sbjct: 1055 PPAPARWPRSDPESQPLLGPGAGG------------AGGTGGAGGGAPAA 1092
Score = 33.5 bits (75), Expect = 0.34
Identities = 43/137 (31%), Positives = 48/137 (35%), Gaps = 40/137 (29%)
Query: 249 GAGLLPG-SLPFGPLLAVPGRPRG---GARRARGDADDAVYHTCFFGDSEPPALPPP--- 301
GAGL G +GP+ P+G G AR A ++PP PPP
Sbjct: 954 GAGLADGFHRYYGPI-----EPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYF 1008
Query: 302 ---------PPPARAF-------GPGPAETPAVGP-----------GPGP-RAALSRSAS 333
PPA AF P A AVGP P P R S S
Sbjct: 1009 AIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPES 1068
Query: 334 VRCAGPGGGGGGGAPGA 350
GPG GG GG GA
Sbjct: 1069 QPLLGPGAGGAGGTGGA 1085
Score = 29.6 bits (65), Expect = 5.0
Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 16 AATPDPAARTPDSEVAPAAPVPTPGPPAAAATP-GPPADELYAALEDYHP 64
A D P + P P P P PPAAAAT GPP L A ED P
Sbjct: 1009 AIVRDKEPAEPPAGAFPGFPSP-PAPPAAAATAVGPPLCRL--AFEDESP 1055
Score = 29.3 bits (64), Expect = 6.5
Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 15 AAATPDPAARTPDSEVAPAAPVPTPGPPAAAATPGP 50
A A P PA P P P+P+P PA PGP
Sbjct: 899 AEAAPPPAKPPP-----PPQPLPSPAYPAPRPAPGP 929
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 46.6 bits (109), Expect = 4e-05
Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 17/65 (26%)
Query: 293 SEPPALPPPPPPA--------RAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGG 344
S PP PPP PP+ +A GP P GPGPGP+ GPGG G
Sbjct: 159 SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG---------PGPGGPKG 209
Query: 345 GGAPG 349
G PG
Sbjct: 210 GKMPG 214
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
Query: 295 PPALPPPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349
P A PPPPPA GPGP P GPGPG + PGGG G PG
Sbjct: 179 PQAGGPPPPPAAVPGPGPG--PKQGPGPGGPKGGKMPGGPK---PGGGPGLSTPG 228
Score = 34.3 bits (77), Expect = 0.20
Identities = 24/78 (30%), Positives = 27/78 (34%), Gaps = 7/78 (8%)
Query: 294 EPPALP-------PPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGG 346
+PP P PPPPP + P A+ P PG G S SA G G
Sbjct: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
Query: 347 APGALWTEAREQALCGPG 364
PG T PG
Sbjct: 146 GPGPTPTPPPAVTSAPPG 163
Score = 33.1 bits (74), Expect = 0.45
Identities = 21/62 (33%), Positives = 23/62 (37%), Gaps = 3/62 (4%)
Query: 293 SEPPALPPPPPPARAFGPGPAETP---AVGPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349
S PPA PP GPGP TP PG S+ V P GG P
Sbjct: 130 SAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA 189
Query: 350 AL 351
A+
Sbjct: 190 AV 191
Score = 30.4 bits (67), Expect = 2.9
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 16/76 (21%)
Query: 291 GDSEP-PALPPPPPPARAFGPGPAETPAVGPGP--------------GPRAALSRSASVR 335
G S P P +PPPPP + P P + P P P P S V
Sbjct: 52 GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVV 111
Query: 336 CAGPGGGGG-GGAPGA 350
GPG G G AP A
Sbjct: 112 AQGPGPAPGVGSAPPA 127
Score = 29.6 bits (65), Expect = 5.0
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 16 AATPDPAARTPDSEVAPAA---PVPTPGPPAAAATPGPP 51
A++ P A P S P + P PTP P +A PG P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP 165
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/162 (29%), Positives = 68/162 (41%), Gaps = 26/162 (16%)
Query: 251 GLLPG-SLPF-GPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALPPPPPPARAF 308
G PG S PF P LA+ +PR A +RG ++ PP LPPPPP R F
Sbjct: 46 GPFPGASAPFLQPPLAL--QPRASAEASRGGGGAGAFYPV-----PPPPLPPPPPQCRPF 98
Query: 309 --------------GPGPAETPAVGPGPGPRAALSRSASVRCAGPGG--GGGGGAPGALW 352
GPGP +P P P A + A+++ G P
Sbjct: 99 PGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAG 158
Query: 353 TEAREQALCGPGLRKTKYRSFRR-RLLKFIPGLNRSLEEEES 393
++ GP L + + R R RL++ + GL+++L E E+
Sbjct: 159 CPVPQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEA 200
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/77 (37%), Positives = 31/77 (40%), Gaps = 17/77 (22%)
Query: 289 FFGDSEPPALPPPPPPARAFG--PGPAETPAV--------GPGPG-------PRAALSRS 331
FFG P PP PPP FG P P +PA GP PG P AL
Sbjct: 6 FFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPR 65
Query: 332 ASVRCAGPGGGGGGGAP 348
AS + GGG G P
Sbjct: 66 ASAEASRGGGGAGAFYP 82
>gi|4759306 lin-7 homolog A [Homo sapiens]
Length = 233
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/77 (32%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 148 GLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQT 207
GL GD + SVNG++VEG H + V+++KA+ + ++L Y + + E+EAR + L+
Sbjct: 148 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLE-EMEARFEKLRTA 206
Query: 208 LYEKWGEYRSLMVQEQR 224
+ + + L++Q+Q+
Sbjct: 207 ---RRRQQQQLLIQQQQ 220
>gi|9966877 golgi associated PDZ and coiled-coil motif containing
isoform a [Homo sapiens]
Length = 462
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 92 SQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPA-QLAGLT 150
SQ RKVL L KED++ G I T G H + + +H PA + GL
Sbjct: 280 SQGVGPIRKVLLL-KEDHEGLGISI-TGGKEHG------VPILISEIHPGQPADRCGGLH 331
Query: 151 PGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLY 188
GD I +VNG+N+ +H+E V I+ + E +Y
Sbjct: 332 VGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVY 369
>gi|62868213 golgi associated PDZ and coiled-coil motif containing
isoform b [Homo sapiens]
Length = 454
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 92 SQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPA-QLAGLT 150
SQ RKVL L KED++ G I T G H + + +H PA + GL
Sbjct: 272 SQGVGPIRKVLLL-KEDHEGLGISI-TGGKEHG------VPILISEIHPGQPADRCGGLH 323
Query: 151 PGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLY 188
GD I +VNG+N+ +H+E V I+ + E +Y
Sbjct: 324 VGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVY 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,347,183
Number of Sequences: 37866
Number of extensions: 1477399
Number of successful extensions: 33141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 648
Number of HSP's successfully gapped in prelim test: 980
Number of HSP's that attempted gapping in prelim test: 17308
Number of HSP's gapped (non-prelim): 13697
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.