Search of human proteins with 29557855

Search of human proteins with 29557855

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
         (324 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]           671   0.0  
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]           657   0.0  
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]          657   0.0  
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]           519   e-147
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]           517   e-147
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]           517   e-147
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]            517   e-147
gi|122937199 protein phosphatase 1B-like [Homo sapiens]               258   7e-69
gi|4505999 protein phosphatase 1G [Homo sapiens]                      134   1e-31
gi|29826282 protein phosphatase 1G [Homo sapiens]                     134   1e-31
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]   124   1e-28
gi|13540531 integrin-linked kinase-associated protein phosphatas...   120   1e-27
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho...   111   8e-25
gi|7661862 protein phosphatase 1F [Homo sapiens]                       96   3e-20
gi|30089948 protein phosphatase 1E [Homo sapiens]                      94   2e-19
gi|4505997 protein phosphatase 1D [Homo sapiens]                       87   2e-17
gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]            57   3e-08
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho...    50   3e-06
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]           49   5e-06
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]           49   5e-06
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo...    48   1e-05
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ...    44   2e-04
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|37221175 PH domain and leucine rich repeat protein phosphatas...    44   3e-04
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom...    42   7e-04
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte...    42   0.001
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int...    42   0.001

>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
          Length = 324

 Score =  671 bits (1732), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 120
           GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 120

Query: 121 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 180
           GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG
Sbjct: 121 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 180

Query: 181 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 240
           SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG
Sbjct: 181 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 240

Query: 241 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300
           IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE
Sbjct: 241 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300

Query: 301 AVKKEAELDKYLECRVEGGSFNKK 324
           AVKKEAELDKYLECRVEGGSFNKK
Sbjct: 301 AVKKEAELDKYLECRVEGGSFNKK 324


>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
          Length = 382

 Score =  657 bits (1694), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 120
           GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 120

Query: 121 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 180
           GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG
Sbjct: 121 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 180

Query: 181 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 240
           SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG
Sbjct: 181 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 240

Query: 241 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300
           IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE
Sbjct: 241 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300

Query: 301 AVKKEAELDKYLECRVE 317
           AVKKEAELDKYLECRVE
Sbjct: 301 AVKKEAELDKYLECRVE 317


>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
          Length = 455

 Score =  657 bits (1694), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD
Sbjct: 74  MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 133

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 120
           GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH
Sbjct: 134 GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 193

Query: 121 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 180
           GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG
Sbjct: 194 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 253

Query: 181 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 240
           SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG
Sbjct: 254 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 313

Query: 241 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300
           IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE
Sbjct: 314 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 373

Query: 301 AVKKEAELDKYLECRVE 317
           AVKKEAELDKYLECRVE
Sbjct: 374 AVKKEAELDKYLECRVE 390


>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
          Length = 327

 Score =  519 bits (1337), Expect = e-147
 Identities = 254/323 (78%), Positives = 285/323 (88%), Gaps = 6/323 (1%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239

Query: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299

Query: 296 KVSPEAVKKEAELDKYLECRVEG 318
           KVS EAVKK++ELDK+LE RVEG
Sbjct: 300 KVSDEAVKKDSELDKHLESRVEG 322


>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
          Length = 380

 Score =  517 bits (1331), Expect = e-147
 Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239

Query: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299

Query: 296 KVSPEAVKKEAELDKYLECRVE 317
           KVS EAVKK++ELDK+LE RVE
Sbjct: 300 KVSDEAVKKDSELDKHLESRVE 321


>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
          Length = 387

 Score =  517 bits (1331), Expect = e-147
 Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239

Query: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299

Query: 296 KVSPEAVKKEAELDKYLECRVE 317
           KVS EAVKK++ELDK+LE RVE
Sbjct: 300 KVSDEAVKKDSELDKHLESRVE 321


>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
          Length = 479

 Score =  517 bits (1331), Expect = e-147
 Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)

Query: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239

Query: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299

Query: 296 KVSPEAVKKEAELDKYLECRVE 317
           KVS EAVKK++ELDK+LE RVE
Sbjct: 300 KVSDEAVKKDSELDKHLESRVE 321


>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
          Length = 430

 Score =  258 bits (658), Expect = 7e-69
 Identities = 137/304 (45%), Positives = 183/304 (60%), Gaps = 8/304 (2%)

Query: 13  HNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCC 72
           H       GLR+G S+ QGWR  MEDAH   + LP     W+ FAV DGH G++ A++  
Sbjct: 56  HGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGA 115

Query: 73  EHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGV 132
            HL  H+   Q+       P  E V+  +R  FL  DE +R +  +    +  G TAV +
Sbjct: 116 RHLPGHVL--QELGPEPSEP--EGVREALRRAFLSADERLRSLWPR---VETGGCTAVVL 168

Query: 133 LISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLA 192
           L+SP+  Y  +CGDSR +L R   V F T+DH+P  P E+ERI  AGG++  +RV GSLA
Sbjct: 169 LVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLA 228

Query: 193 VSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCD 252
           VSRALGDF YK   G+ P  QLVS EPEV  + R  E D+F++LA DG+WD +    L  
Sbjct: 229 VSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQAE-DEFMLLASDGVWDTVSGAALAG 287

Query: 253 FVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYL 312
            V SRL +    E +C +++DTCL KGS DNM+ IL+CFP AP+ S EA+++E  LD  L
Sbjct: 288 LVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAAL 347

Query: 313 ECRV 316
            CR+
Sbjct: 348 GCRI 351


>gi|4505999 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score =  134 bits (337), Expect = 1e-31
 Identities = 86/235 (36%), Positives = 131/235 (55%), Gaps = 18/235 (7%)

Query: 107 EIDEHMRV--MSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDH 164
           E +E M V  M  K+     SG+TAV  LI  +     N GDSR ++    K    + DH
Sbjct: 307 EEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDH 366

Query: 165 KPSNPLEKERIQNAGGSV-MIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD 223
           KP + +E  RI+NAGG V M  RVNG L +SRA+GD  YK      P EQ++S  P++  
Sbjct: 367 KPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKV 426

Query: 224 IERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDD------LEKVCNEVVDTCLY 277
           +  + +D +F+++ACDGIW+VM ++E+ DF++S++   D+      L  +  E++D CL 
Sbjct: 427 LTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLA 485

Query: 278 KGSR------DNMSVILICFP--NAPKVSPEAVKKEAELDKYLECRVEGGSFNKK 324
             +       DNM+ I+ICF   N  ++ PE+ K++ E     E   E G+ +KK
Sbjct: 486 PDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 47/129 (36%), Positives = 65/129 (50%), Gaps = 13/129 (10%)

Query: 1   MGAFLDKPKMEKHNAQGQGNG---LRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA 57
           MGA+L +P   K +  G G     L YG S+MQGWRV MEDAH  +  L S     + F+
Sbjct: 1   MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFS 57

Query: 58  VYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSE 117
           VYDGH G +VA YC ++L D I + + +K          ++  +   FL ID  +     
Sbjct: 58  VYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-------KLQKALEDAFLAIDAKLTTEEV 110

Query: 118 KKHGADRSG 126
            K  A  +G
Sbjct: 111 IKELAQIAG 119


>gi|29826282 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score =  134 bits (337), Expect = 1e-31
 Identities = 86/235 (36%), Positives = 131/235 (55%), Gaps = 18/235 (7%)

Query: 107 EIDEHMRV--MSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDH 164
           E +E M V  M  K+     SG+TAV  LI  +     N GDSR ++    K    + DH
Sbjct: 307 EEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDH 366

Query: 165 KPSNPLEKERIQNAGGSV-MIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD 223
           KP + +E  RI+NAGG V M  RVNG L +SRA+GD  YK      P EQ++S  P++  
Sbjct: 367 KPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKV 426

Query: 224 IERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDD------LEKVCNEVVDTCLY 277
           +  + +D +F+++ACDGIW+VM ++E+ DF++S++   D+      L  +  E++D CL 
Sbjct: 427 LTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLA 485

Query: 278 KGSR------DNMSVILICFP--NAPKVSPEAVKKEAELDKYLECRVEGGSFNKK 324
             +       DNM+ I+ICF   N  ++ PE+ K++ E     E   E G+ +KK
Sbjct: 486 PDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKK 540



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 47/129 (36%), Positives = 65/129 (50%), Gaps = 13/129 (10%)

Query: 1   MGAFLDKPKMEKHNAQGQGNG---LRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA 57
           MGA+L +P   K +  G G     L YG S+MQGWRV MEDAH  +  L S     + F+
Sbjct: 1   MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFS 57

Query: 58  VYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSE 117
           VYDGH G +VA YC ++L D I + + +K          ++  +   FL ID  +     
Sbjct: 58  VYDGHGGEEVALYCAKYLPDIIKDQKAYKEG-------KLQKALEDAFLAIDAKLTTEEV 110

Query: 118 KKHGADRSG 126
            K  A  +G
Sbjct: 111 IKELAQIAG 119


>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
          Length = 360

 Score =  124 bits (311), Expect = 1e-28
 Identities = 86/278 (30%), Positives = 141/278 (50%), Gaps = 19/278 (6%)

Query: 28  SMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNN-QDFK 86
           S+QG R  MED    +  L +     S F ++DGH G   A+Y    L + +  + QD++
Sbjct: 97  SIQGRRDHMEDRFEVLTDLANKTHP-SIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYE 155

Query: 87  GSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGD 146
                 SV + +  +    L ID  M  + +     D +G+T +  L+S +     N GD
Sbjct: 156 KDK-ENSVLSYQTILEQQILSIDREM--LEKLTVSYDEAGTTCLIALLSDKDLTVANVGD 212

Query: 147 SRGLLC-RNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ---RVNGSLAVSRALGDFDY 202
           SRG+LC ++      + DHKP    E++RI+ AGG +      RV G LA+SR+LGD+  
Sbjct: 213 SRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPL 272

Query: 203 KCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTD 262
           K ++       +V P+P++   +  +   +F+ILA DG+WD   NEE   F++ RL   D
Sbjct: 273 KNLN-------VVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERL---D 322

Query: 263 DLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 300
           +       +V    Y+G  DN++V+++ F N+ K   +
Sbjct: 323 EPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ 360


>gi|13540531 integrin-linked kinase-associated protein phosphatase
           2C [Homo sapiens]
          Length = 392

 Score =  120 bits (302), Expect = 1e-27
 Identities = 99/298 (33%), Positives = 147/298 (49%), Gaps = 44/298 (14%)

Query: 21  GLRYGLSSMQGWRVEMEDAHTAVIGL------PSGLESW-SFFAVYDGHAGSQVAKYCCE 73
           GL+  ++  +G R EM+DAH  +  +      PS L +  S+FAV+DGH G + +K+  +
Sbjct: 106 GLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQ 165

Query: 74  HLLDHITNNQDFKGSAGAPSVEN-VKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGV 132
           +L  ++      KG     SVE  VK  +   F   DE     +  +  A + GSTA  V
Sbjct: 166 NLHQNLIRKFP-KGDV--ISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCV 222

Query: 133 LISPQHTYFINCGDSRGLLCRNRKVH------FFTQDHKPSNPLEKERIQNAGGSVMIQR 186
           L      Y  N GDSR +LCR  +          +++H P+   E+ RIQ AGG+V   R
Sbjct: 223 LAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGR 282

Query: 187 VNGSLAVSRALGDFDYK-CVHGKGPTEQLVSPEPEVHDIERSE--EDDQFIILACDGIWD 243
           V G L VSR++GD  YK C    G T         V DI R +   +D+FI+LACDG++ 
Sbjct: 283 VLGVLEVSRSIGDGQYKRC----GVT--------SVPDIRRCQLTPNDRFILLACDGLFK 330

Query: 244 VMGNEELCDFVRSRLE------------VTDDLEKVCNEVVDTCLYKGSRDNMSVILI 289
           V   EE  +F+ S LE                 E  CN + +  + +GS DN++V+++
Sbjct: 331 VFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVV 388


>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
           sapiens]
          Length = 372

 Score =  111 bits (278), Expect = 8e-25
 Identities = 88/277 (31%), Positives = 130/277 (46%), Gaps = 36/277 (12%)

Query: 25  GLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQD 84
           G +S  G R E ED            +   +FAVYDGH G   A +C  H+   I +   
Sbjct: 96  GCASQIGKRKENEDR----FDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL-- 149

Query: 85  FKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADR----SGSTA-VGVLISPQHT 139
                  P  +N++  +   FLEID+     S  +  AD     SG+TA V +L      
Sbjct: 150 ------LPKEKNLETLLTLAFLEIDKAFS--SHARLSADATLLTSGTTATVALLRDGIEL 201

Query: 140 YFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG-----SVMIQRVNGSLAVS 194
              + GDSR +LCR  K    T DH P    EKERI+  GG     S+    VNG LA++
Sbjct: 202 VVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMT 261

Query: 195 RALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
           R++GD D K       T  +++ EPE   I+    DD F++L  DGI  ++ ++E+CDFV
Sbjct: 262 RSIGDLDLK-------TSGVIA-EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFV 313

Query: 255 RSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICF 291
                   D  +  + V +  +  G+ DN + +++ F
Sbjct: 314 NQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346


>gi|7661862 protein phosphatase 1F [Homo sapiens]
          Length = 454

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 83/277 (29%), Positives = 134/277 (48%), Gaps = 37/277 (13%)

Query: 26  LSSMQGWRVEMEDAHTAVIGLPS-----GLE---SWSFFAVYDGHAGSQVAKYCCEHLLD 77
           + +++  R +MED H   + LPS     GL    + ++FAV+DGH G   A+Y   H+  
Sbjct: 159 IHAIRNTRRKMEDRH---VSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV-- 213

Query: 78  HITNNQDFKGSAGAPSVENVKNG-IRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISP 136
                     +A  P +     G +R  F   D+    + + K    +SG+T V  LI+ 
Sbjct: 214 -------HTNAARQPELPTDPEGALREAFRRTDQMF--LRKAKRERLQSGTTGVCALIAG 264

Query: 137 QHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVM---IQRVNGSLAV 193
              +    GDS+ +L +  +V    + H+P    EK RI+  GG V      RVNG+LAV
Sbjct: 265 ATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAV 324

Query: 194 SRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDF 253
           SRA+GD   K           VS E +      +  +D +++LACDG +DV+ ++E+   
Sbjct: 325 SRAIGDVFQK---------PYVSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGL 374

Query: 254 VRSRLEVTDDLE-KVCNEVVDTCLYKGSRDNMSVILI 289
           V+S L        +V  E+V     +GS DN++V+++
Sbjct: 375 VQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 85/304 (27%), Positives = 135/304 (44%), Gaps = 36/304 (11%)

Query: 26  LSSMQGWRVEMEDAHTAVIGLP-----SGLESWSFFAVYDGHAGSQVAKYCCEHLLDHIT 80
           + +++  R +MED H  +            E  ++FAV+DGH G   A Y   HL  ++ 
Sbjct: 234 IHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLV 293

Query: 81  NNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTY 140
             + F          +    +   F   DE  R + +    + R G+T V   I     +
Sbjct: 294 RQEMFP--------HDPAEALCRAFRVTDE--RFVQKAARESLRCGTTGVVTFIRGNMLH 343

Query: 141 FINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVM---IQRVNGSLAVSRAL 197
               GDS+ +L R  +     + HKP    EK+RI+  GG V+     RVNGSL+VSRA+
Sbjct: 344 VAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAI 403

Query: 198 GDFDYK-CVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRS 256
           GD ++K  + G   +   V            +  + ++ILACDG +D +  +E    V  
Sbjct: 404 GDAEHKPYICGDADSASTV-----------LDGTEDYLILACDGFYDTVNPDEAVKVVSD 452

Query: 257 RL-EVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECR 315
            L E   D   V +++V +    GS DN++VI++   +  K    AV    E D + E  
Sbjct: 453 HLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNK----AVNVSEESD-WTENS 507

Query: 316 VEGG 319
            +GG
Sbjct: 508 FQGG 511


>gi|4505997 protein phosphatase 1D [Homo sapiens]
          Length = 605

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 87/292 (29%), Positives = 130/292 (44%), Gaps = 53/292 (18%)

Query: 52  SWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEH 111
           S +FFAV DGH G + A++  EHL   I   + F  S  A     ++ G     L + + 
Sbjct: 97  SVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKK 156

Query: 112 MRVMSEKKHG-ADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF-----FTQD 163
           +    +   G    SG+TA  V+I     Y  + GDS  +L    + K  F      TQD
Sbjct: 157 LAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQD 216

Query: 164 HKPSNPLEKERIQNAGGSVM----IQRV---------NGS------------LAVSRALG 198
           HKP  P E+ERI+  GGSVM    + RV         NG             LAV+RALG
Sbjct: 217 HKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALG 276

Query: 199 D-FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSR 257
           D + Y    G    E +VSPEP+        +  ++IIL  DG+W+++  ++     + +
Sbjct: 277 DLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQ 332

Query: 258 LE----VTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICFPNAPKVSPE 300
            E    + +  +     +V+  L +  +     DN S I+IC      +SPE
Sbjct: 333 EEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVIC------ISPE 378


>gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]
          Length = 192

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 25/34 (73%), Positives = 31/34 (91%)

Query: 284 MSVILICFPNAPKVSPEAVKKEAELDKYLECRVE 317
           MS++L+CF NAPKVS EAVKK++ELDK+LE RVE
Sbjct: 1   MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVE 34


>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
           sapiens]
          Length = 514

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEED---DQFIILACDGIW 242
           RV  ++ V+R LGD D K        +  +S  PEV   + S+ D   D  +ILA DG+W
Sbjct: 381 RVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLW 440

Query: 243 DVMGNEELCDFVRSRLEVTD 262
           DV+ NEE+ + +   L   D
Sbjct: 441 DVLSNEEVAEAITQFLPNCD 460


>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
          Length = 247

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVH--DIERSE-EDDQFIILACDGIW 242
           R+ G+LAVSR LGD   + +      +  +   P+V   D+++ E ++D  +++A DG+W
Sbjct: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175

Query: 243 DVMGNEELCDFVRSRL 258
           DV+ NE++   VRS L
Sbjct: 176 DVLSNEQVAWLVRSFL 191


>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
          Length = 298

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 53/237 (22%), Positives = 92/237 (38%), Gaps = 64/237 (27%)

Query: 81  NNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQ-HT 139
           ++  F    G  + + V   + + F E DE   V+  +   + + G     V +S Q   
Sbjct: 11  SDPQFVEEKGIRAEDLVIGALESAFQECDE---VIGRELEASGQMGGCTALVAVSLQGKL 67

Query: 140 YFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQN---------AGGSVMIQ---RV 187
           Y  N GDSR +L R  ++   + +  P    E++RIQ          AG    ++   R+
Sbjct: 68  YMANAGDSRAILVRRDEIRPLSFEFTPET--ERQRIQQLAFVYPELLAGEFTRLEFPRRL 125

Query: 188 NGSLAVSRAL----------------GDFDYKCVHGKGPTEQLVS--------------- 216
            G     + L                 D  Y  +HG+G   +L+                
Sbjct: 126 KGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRV 185

Query: 217 --------------PEPEVHDIERSE-EDDQFIILACDGIWDVMGNEELCDFVRSRL 258
                         P+  V D+++ E ++D  +++A DG+WDV+ NE++   VRS L
Sbjct: 186 LDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFL 242


>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
           sapiens]
          Length = 529

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/172 (26%), Positives = 65/172 (37%), Gaps = 35/172 (20%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFF-----TQDHKPSNPLEKERIQNAG 179
           SG+TA    +   H +  N GD R +L        +     T+DH   N  E  R++   
Sbjct: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREH 324

Query: 180 GS------VMIQRVNGSLAVSRALGDFDYKC-------------------VHGKGPTEQL 214
                   +M  R+ G L   RA GD   K                    ++   P    
Sbjct: 325 PESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYY 384

Query: 215 VSP----EPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTD 262
             P    EPEV    R    D+F++LA DG+WD++ NE++   V   L   D
Sbjct: 385 TPPYLTAEPEV-TYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435


>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
           SG+TA    +     +  N GDSR +L    +         + DH   N  E ER++   
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329

Query: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389

Query: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
            T   ++ EPEV    R    D+F++LA DG+W+ M  +++   V
Sbjct: 390 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 433


>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
           SG+TA    +     +  N GDSR +L    +         + DH   N  E ER++   
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329

Query: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389

Query: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
            T   ++ EPEV    R    D+F++LA DG+W+ M  +++   V
Sbjct: 390 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 433


>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
           SG+TA    +     +  N GDSR +L    +         + DH   N  E ER++   
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354

Query: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414

Query: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
            T   ++ EPEV    R    D+F++LA DG+W+ M  +++   V
Sbjct: 415 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458


>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
           SG+TA    +     +  N GDSR +L    +         + DH   N  E ER++   
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354

Query: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414

Query: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
            T   ++ EPEV    R    D+F++LA DG+W+ M  +++   V
Sbjct: 415 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458


>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 1 [Homo sapiens]
          Length = 596

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)

Query: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
           SG+TA    +     +  N GDSR +L    +         + DH   N  E ER++   
Sbjct: 329 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 388

Query: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 389 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 448

Query: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
            T   ++ EPEV    R    D+F++LA DG+W+ M  +++   V
Sbjct: 449 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 492


>gi|37221175 PH domain and leucine rich repeat protein phosphatase
           [Homo sapiens]
          Length = 1205

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 15/148 (10%)

Query: 143 NCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ-RVNGSLAVSRALGDFD 201
           N G  + +LCRN K    ++ +  S   E +RI+     +    +VNG    +R LG   
Sbjct: 775 NVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILG--- 831

Query: 202 YKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVT 261
           Y  +H        V P P V  +  + +D+ F IL   G+WD +  EE  + VR+  +  
Sbjct: 832 YTFLHPS------VVPRPHVQSVLLTPQDE-FFILGSKGLWDSLSVEEAVEAVRNVPDAL 884

Query: 262 DDLEKVCNEVVDTCLYKGSRDNMSVILI 289
              +K+C          G  D++S +++
Sbjct: 885 AAAKKLCT----LAQSYGCHDSISAVVV 908


>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
           sapiens]
          Length = 505

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 52/227 (22%), Positives = 82/227 (36%), Gaps = 65/227 (28%)

Query: 97  VKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRK 156
           V   +   F  +DE M    E++      G  A+ V+      Y  N GDSR ++ RN +
Sbjct: 232 VVGAVENAFQLMDEQMA--RERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGE 289

Query: 157 VHFFTQDHKPSNPLEKERIQNAG-------------------------GSVMIQR----- 186
           +   +++  P    E++R+Q  G                         G  M+ R     
Sbjct: 290 IIPMSREFTPET--ERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMT 347

Query: 187 -------------------------VNGSLAVSRALGDFDYKCVHGKGPTEQLVS--PEP 219
                                    V  ++ V+R LGD   K      P +  +S  PE 
Sbjct: 348 GWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEV 407

Query: 220 EVHDIERSEE-DDQFIILACDGIWDVMGNEELC---DFVRSRLEVTD 262
            V+D+ + E   D  ++L  DG+WDV  + E+    D V S  E  D
Sbjct: 408 RVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPND 454


>gi|5174703 mitogen-activated protein kinase kinase kinase 7
           interacting protein 1 isoform alpha [Homo sapiens]
          Length = 504

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 28/191 (14%)

Query: 105 FLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNR----KVHFF 160
           + +I E ++ +  +  G    G+ AV  ++     Y  N G +R LLC++     +V   
Sbjct: 148 YQKILERLKTLEREISG----GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQL 203

Query: 161 TQDHKPSNPLEKERIQNAG---GSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQL--- 214
             DH   N  E  R+   G   G +    +      +R +G  DYK  +G    + L   
Sbjct: 204 NVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIG--DYKVKYGYTDIDLLSAA 261

Query: 215 ----VSPEPEVHDIERSEEDDQFIILACDGIWDVM--------GNEELCDFVRSRLEVTD 262
               +  EPE+H  +  +    F++L  +G++  +         N+E+   + +      
Sbjct: 262 KSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQT 321

Query: 263 DLEKVCNEVVD 273
            L+ V   VVD
Sbjct: 322 SLDAVAQAVVD 332


>gi|41281798 mitogen-activated protein kinase kinase kinase 7
           interacting protein 1 isoform beta [Homo sapiens]
          Length = 462

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 28/191 (14%)

Query: 105 FLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNR----KVHFF 160
           + +I E ++ +  +  G    G+ AV  ++     Y  N G +R LLC++     +V   
Sbjct: 148 YQKILERLKTLEREISG----GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQL 203

Query: 161 TQDHKPSNPLEKERIQNAG---GSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQL--- 214
             DH   N  E  R+   G   G +    +      +R +G  DYK  +G    + L   
Sbjct: 204 NVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIG--DYKVKYGYTDIDLLSAA 261

Query: 215 ----VSPEPEVHDIERSEEDDQFIILACDGIWDVM--------GNEELCDFVRSRLEVTD 262
               +  EPE+H  +  +    F++L  +G++  +         N+E+   + +      
Sbjct: 262 KSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQT 321

Query: 263 DLEKVCNEVVD 273
            L+ V   VVD
Sbjct: 322 SLDAVAQAVVD 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,771,753
Number of Sequences: 37866
Number of extensions: 636073
Number of successful extensions: 1289
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1193
Number of HSP's gapped (non-prelim): 53
length of query: 324
length of database: 18,247,518
effective HSP length: 102
effective length of query: 222
effective length of database: 14,385,186
effective search space: 3193511292
effective search space used: 3193511292
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.