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Search of human proteins with 217416343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416343 fibrosin-like 1 [Homo sapiens]
(1045 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416343 fibrosin-like 1 [Homo sapiens] 2158 0.0
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 619 e-177
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 616 e-176
gi|157364934 fibrosin [Homo sapiens] 215 2e-55
gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo s... 117 4e-26
gi|163965366 nascent polypeptide-associated complex alpha subuni... 78 5e-14
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 76 2e-13
gi|55750053 atrophin-1 [Homo sapiens] 75 4e-13
gi|55750041 atrophin-1 [Homo sapiens] 75 4e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 66 2e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 3e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 4e-09
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 59 2e-08
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 59 2e-08
gi|117938759 GNAS complex locus XLas [Homo sapiens] 59 3e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 57 7e-08
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 57 9e-08
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 57 9e-08
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 56 2e-07
gi|157266334 tubby like protein 1 [Homo sapiens] 56 2e-07
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 55 3e-07
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 55 3e-07
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 55 4e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 55 4e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 55 4e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 55 4e-07
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 54 6e-07
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 54 6e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 54 6e-07
>gi|217416343 fibrosin-like 1 [Homo sapiens]
Length = 1045
Score = 2158 bits (5591), Expect = 0.0
Identities = 1045/1045 (100%), Positives = 1045/1045 (100%)
Query: 1 MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPA 60
MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPA
Sbjct: 1 MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPA 60
Query: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR
Sbjct: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
Query: 121 ESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDS 180
ESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDS
Sbjct: 121 ESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDS 180
Query: 181 VLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK 240
VLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK
Sbjct: 181 VLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK 240
Query: 241 AGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQ 300
AGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQ
Sbjct: 241 AGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQ 300
Query: 301 PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHL 360
PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHL
Sbjct: 301 PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHL 360
Query: 361 STSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQ 420
STSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQ
Sbjct: 361 STSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQ 420
Query: 421 SAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDK 480
SAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDK
Sbjct: 421 SAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDK 480
Query: 481 YAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVS 540
YAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVS
Sbjct: 481 YAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVS 540
Query: 541 TCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAW 600
TCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAW
Sbjct: 541 TCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAW 600
Query: 601 QIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPA 660
QIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPA
Sbjct: 601 QIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPA 660
Query: 661 SNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEG 720
SNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEG
Sbjct: 661 SNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEG 720
Query: 721 SSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLL 780
SSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLL
Sbjct: 721 SSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLL 780
Query: 781 EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMP 840
EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMP
Sbjct: 781 EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMP 840
Query: 841 ARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRG 900
ARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRG
Sbjct: 841 ARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRG 900
Query: 901 LELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPAL 960
LELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPAL
Sbjct: 901 LELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPAL 960
Query: 961 DGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTT 1020
DGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTT
Sbjct: 961 DGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTT 1020
Query: 1021 PLGGLGPGEARDYSPSRNPPEVEAR 1045
PLGGLGPGEARDYSPSRNPPEVEAR
Sbjct: 1021 PLGGLGPGEARDYSPSRNPPEVEAR 1045
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 619 bits (1596), Expect = e-177
Identities = 481/1300 (37%), Positives = 594/1300 (45%), Gaps = 309/1300 (23%)
Query: 5 VRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGL----RGAPPRGAAPA 60
+R RRSR+QRDR RR A A ++G G PP + A
Sbjct: 10 LRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---SSA 66
Query: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
P RPPRR+RRES+S EE++IDGFA+ SF T EALEKD+ALKP ER EK + L KK R
Sbjct: 67 PSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKR 126
Query: 121 ESETCPPAEPSENRR---PLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSD 177
E+ T + S+ R P S ++ C K P ++ + RDSD
Sbjct: 127 EALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSD 186
Query: 178 DDSV------LEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKAS-VGSEKLFA----- 225
+S +SSR+ LSDSSA + G GY CDS+S ++KAS SEKLF
Sbjct: 187 SESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
Query: 226 --PGTDKGPALEKSEAKAGP-VPKVSGLERSRELSAESFL-PTASPAPHAAPCPG----- 276
P G E AGP VPK+SGLERS+E S + P P PCP
Sbjct: 247 KDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPI 306
Query: 277 ---------------------------PPPGSRANPLVKKEP---PAPHRHTPQPPPPQ- 305
PPP S P E PAP +PP PQ
Sbjct: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
Query: 306 PRGLLPTHVPA--------SLGAFAGHSQAAANGLHGLSRSSS--------APLGLGKHV 349
P LL ++P SL +++ L+ LS S S AP + H
Sbjct: 367 PTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
Query: 350 SLSPHGPGPHLSTSHLALRS------QAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHP 403
S SP P +H L S H H MFA P LPPPP L + SL + GHP
Sbjct: 427 SASPF---PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
Query: 404 A-----DHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQH 458
A + ++LRQELNTRFL + GASLGP LR EFHQHQH HQHTHQHTHQH
Sbjct: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQH-- 541
Query: 459 TFAPFPAGLPPT---PPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP 515
TF PFP +PPT P APP FDKY K+D P++RHS F S+PPA+ G+P ++P
Sbjct: 542 TFTPFPHAIPPTAIMPTPAPPMFDKYPTKVD-PFYRHS---LFHSYPPAVSGIPPMIPPT 597
Query: 516 GPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQ-GRTLVPPGRPRGARDSRSLQKTWVGV 574
GPFGSLQGAFQPK S+P + T Q L P RP
Sbjct: 598 GPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRP---------------- 641
Query: 575 APAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK-EMQLDPHKLEVGAKLDLFGRPPA 633
+ +KPG+WCA+HV IAWQIY HQQK+K +MQ DPHKL+ G K + RPP
Sbjct: 642 ---------MLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPG 692
Query: 634 PGVFAGFHYPQDLARP--LFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGG 691
P +F H+P DLARP LF + GAAHP PFGP H +FL +PF+RPSTF G
Sbjct: 693 PSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTG 752
Query: 692 LGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPK 751
L ++ +AFGGLG+ ++ P S+F K+G SV +PHE WNRLHR PPSFP PPPW K
Sbjct: 753 LAAVGGNAFGGLGNPSVTPN-SMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLK 811
Query: 752 SVDAERVSALTNHDREPD-------NGKEEQERDLLEKTRLLSRASPA-----TPAGHPV 799
+ ER ++ HDR+ D K+++ER+ +EK R S SPA GH
Sbjct: 812 PGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK-RHSSHPSPAPVLPVNALGHTR 870
Query: 800 SG---LLLRAQSELGRSGAPAEREA------------EPRVKESRSPAKE---------- 834
S + +E P ERE E + KE P K+
Sbjct: 871 SSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 930
Query: 835 EAAKMPARASPPH------SKAAP-----------------------GDVKVKEERGED- 864
E AK AR P+ A P +VKVKEER ED
Sbjct: 931 EEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDH 990
Query: 865 ----------EASEPP----AGGLHPAPLQ-----------------------------L 881
ASEPP + +HP PL +
Sbjct: 991 DLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFM 1050
Query: 882 GL----GRERLGAPGFAWEPFRG-LELPRRAFPAAAPAP--------------GSAALLE 922
G+ G ER P F W+P R L P R P S L
Sbjct: 1051 GISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLY 1110
Query: 923 PPERPYRDREPHGYS-------------PER----------------LRGELERARAPHL 953
+R +RDREPH YS P R LR + E R +
Sbjct: 1111 EADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSV 1170
Query: 954 PPAAPALDGAL------LPSLGALHFPRLSP-AALHNGLLARTPPAAAALGAPPPLV-TA 1005
PA +LDG L P L ++H+PR+SP A NGLL +TPP AAL APPPL+ T
Sbjct: 1171 HPA--SLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPP-TAALSAPPPLISTL 1227
Query: 1006 AGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR 1045
G P P RTTPL E R+ PS ++EAR
Sbjct: 1228 GGRPVSP----RRTTPLS----AEIRERPPSHTLKDIEAR 1259
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 616 bits (1588), Expect = e-176
Identities = 476/1299 (36%), Positives = 591/1299 (45%), Gaps = 331/1299 (25%)
Query: 5 VRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGL----RGAPPRGAAPA 60
+R RRSR+QRDR RR A A ++G G PP + A
Sbjct: 10 LRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---SSA 66
Query: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
P RPPRR+RRES+S EE++IDGFA+ SF T EALEKD+ALKP ER EK + L KK R
Sbjct: 67 PSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKR 126
Query: 121 ESETCPPAEPSENRR---PLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSD 177
E+ T + S+ R P S ++ C K P ++ + RDSD
Sbjct: 127 EALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSD 186
Query: 178 DDSV------LEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKAS-VGSEKLFA----- 225
+S +SSR+ LSDSSA + G GY CDS+S ++KAS SEKLF
Sbjct: 187 SESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
Query: 226 --PGTDKGPALEKSEAKAGP-VPKVSGLERSRELSAESFL-PTASPAPHAAPCPG----- 276
P G E AGP VPK+SGLERS+E S + P P PCP
Sbjct: 247 KDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPI 306
Query: 277 ---------------------------PPPGSRANPLVKKEP---PAPHRHTPQPPPPQ- 305
PPP S P E PAP +PP PQ
Sbjct: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
Query: 306 PRGLLPTHVPA--------SLGAFAGHSQAAANGLHGLSRSSS--------APLGLGKHV 349
P LL ++P SL +++ L+ LS S S AP + H
Sbjct: 367 PTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
Query: 350 SLSPHGPGPHLSTSHLALRS------QAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHP 403
S SP P +H L S H H MFA P LPPPP L + SL + GHP
Sbjct: 427 SASPF---PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
Query: 404 A-----DHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQH 458
A + ++LRQELNTRFL + GASLGP LR EFHQHQH HQHTHQHTHQH
Sbjct: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQH-- 541
Query: 459 TFAPFPAGLPPT---PPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP 515
TF PFP +PPT P APP FDKY K+D P++RHS F S+PPA+ G+P ++P
Sbjct: 542 TFTPFPHAIPPTAIMPTPAPPMFDKYPTKVD-PFYRHS---LFHSYPPAVSGIPPMIPPT 597
Query: 516 GPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVA 575
GPFGSLQGAFQPK++DP+R +++
Sbjct: 598 GPFGSLQGAFQPKLTDPFRPMLR------------------------------------- 620
Query: 576 PAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK-EMQLDPHKLEVGAKLDLFGRPPAP 634
KPG+WCA+HV IAWQIY HQQK+K +MQ DPHKL+ G K + RPP P
Sbjct: 621 -----------KPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGP 669
Query: 635 GVFAGFHYPQDLARP--LFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGL 692
+F H+P DLARP LF + GAAHP PFGP H +FL +PF+RPSTF GL
Sbjct: 670 SLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGL 729
Query: 693 GSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKS 752
++ +AFGGLG+ ++ P S+F K+G SV +PHE WNRLHR PPSFP PPPW K
Sbjct: 730 AAVGGNAFGGLGNPSVTPN-SMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKP 788
Query: 753 VDAERVSALTNHDREPD-------NGKEEQERDLLEKTRLLSRASPA-----TPAGHPVS 800
+ ER ++ HDR+ D K+++ER+ +EK R S SPA GH S
Sbjct: 789 GELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK-RHSSHPSPAPVLPVNALGHTRS 847
Query: 801 G---LLLRAQSELGRSGAPAEREA------------EPRVKESRSPAKE----------E 835
+ +E P ERE E + KE P K+ E
Sbjct: 848 STEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGE 907
Query: 836 AAKMPARASPPH------SKAAP-----------------------GDVKVKEERGED-- 864
AK AR P+ A P +VKVKEER ED
Sbjct: 908 EAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHD 967
Query: 865 ---------EASEPP----AGGLHPAPLQ-----------------------------LG 882
ASEPP + +HP PL +G
Sbjct: 968 LPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMG 1027
Query: 883 L----GRERLGAPGFAWEPFRG-LELPRRAFPAAAPAP--------------GSAALLEP 923
+ G ER P F W+P R L P R P S L
Sbjct: 1028 ISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYE 1087
Query: 924 PERPYRDREPHGYS-------------PER----------------LRGELERARAPHLP 954
+R +RDREPH YS P R LR + E R +
Sbjct: 1088 ADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147
Query: 955 PAAPALDGAL------LPSLGALHFPRLSP-AALHNGLLARTPPAAAALGAPPPLV-TAA 1006
PA +LDG L P L ++H+PR+SP A NGLL +TPP AAL APPPL+ T
Sbjct: 1148 PA--SLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPP-TAALSAPPPLISTLG 1204
Query: 1007 GPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR 1045
G P P RTTPL E R+ PS ++EAR
Sbjct: 1205 GRPVSP----RRTTPLS----AEIRERPPSHTLKDIEAR 1235
>gi|157364934 fibrosin [Homo sapiens]
Length = 460
Score = 215 bits (547), Expect = 2e-55
Identities = 209/570 (36%), Positives = 261/570 (45%), Gaps = 130/570 (22%)
Query: 478 FDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVV 537
F+KY K++ FRH+ + +FPPA+PGLP LP FGSLQGAFQPK ++P
Sbjct: 2 FEKYPGKMEG-LFRHNP---YTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNP-ELPP 56
Query: 538 KVSTCWEGPWQGRTLVPPG-RPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHV 596
++ G Q T +P RP PL +KPG+WCA+HV
Sbjct: 57 RLGPVPSGLSQKGTQIPDHFRP-------------------PL------RKPGKWCAMHV 91
Query: 597 QIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARP--LFPST 654
++A+ I RHQ+K+K D HKL+ + DL P PG + Q+L+ P LF +T
Sbjct: 92 RVAYMILRHQEKMKG---DSHKLDF--RNDLL--PCLPGPYGALPPGQELSHPASLFTAT 144
Query: 655 GAAHPASNPF--GPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGG 712
GA H A+NPF P AH G FL DPF RP++F L +LS+ AFGGLGS G
Sbjct: 145 GAVHAAANPFTAAPGAH-GPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFN-SG 202
Query: 713 SIFAPKEGSSVH-GLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTN----HDRE 767
++FA KE SP + W RLHR+P +FPA W + +A R RE
Sbjct: 203 AVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPA---WVRPPEAARTPGSDKERPVERRE 259
Query: 768 PDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKE 827
P KEE++RD L +R R SPATP ++ G G P + RVKE
Sbjct: 260 PSITKEEKDRD-LPFSRPQLRVSPATP------------KARAGEEG-PRPTKESVRVKE 305
Query: 828 SRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRER 887
R KEEAA A A+ + AA A+ GLH L ER
Sbjct: 306 ER---KEEAAAAAAAAAAAAAAAA--------------AAATGPQGLH-------LLFER 341
Query: 888 LGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEP---PERPYRDREPHGY-SPERLR- 942
P PF G P R A LEP P R P Y + E L
Sbjct: 342 PRPP-----PFLGPSPPDRC----------AGFLEPTWLAAPPRLARPPRFYEAGEELTG 386
Query: 943 -GELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPP 1001
G + AR L PA P L L P P +P H LL++TPP A LGAPPP
Sbjct: 387 PGAVAAARLYGLEPAHPLLYSRLAPPPP----PAAAPGTPH--LLSKTPP-GALLGAPPP 439
Query: 1002 LVTAAGPPTPPGPPRSRTTPLGGLGPGEAR 1031
LV A P P PPR GPG AR
Sbjct: 440 LVPA---PRPSSPPR---------GPGPAR 457
>gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo
sapiens]
Length = 266
Score = 117 bits (294), Expect = 4e-26
Identities = 90/238 (37%), Positives = 115/238 (48%), Gaps = 22/238 (9%)
Query: 5 VRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGL----RGAPPRGAAPA 60
+R RRSR+QRDR RR A A ++G G PP + A
Sbjct: 10 LRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---SSA 66
Query: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
P RPPRR+RRES+S EE++IDGFA+ SF T EALEKD+ALKP ER EK + L KK R
Sbjct: 67 PSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKR 126
Query: 121 ESETCPPAEPSENRR---PLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSD 177
E+ T + S+ R P S ++ C K P ++ + RDSD
Sbjct: 127 EALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSD 186
Query: 178 DDSV------LEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTD 229
+S +SSR+ LSDSSA + G GY SG K +G E G D
Sbjct: 187 SESASGESKGFHRSSSRERLSDSSAPSSLGTGY---FRSG---KMCLGEEACLKSGND 238
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 77.8 bits (190), Expect = 5e-14
Identities = 246/1056 (23%), Positives = 329/1056 (31%), Gaps = 212/1056 (20%)
Query: 100 MALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVP-- 157
+A K H KE L P SE CP A +N +P L A + + VP
Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN-----TCAPLATLVLAPEIPKSVPSP 737
Query: 158 -LQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAV-SGRGYSCDSESGPDDK 215
L P+ T G + + + ++ P DS A A S +G P
Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797
Query: 216 ASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTAS--------- 266
S + P T KG AGP + L SFLP S
Sbjct: 798 GVSVSPQTKRPPTKKG--------SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 267 PAPHAAPCPGPPPG----SRANPLVKKEPPAPHRHTPQP-------PPPQPRGLLPTHVP 315
PA +P P P G S PL K P + TP P P P P P
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 316 ASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGP--GPHLSTSHLALRSQAQH 373
A + +A A +S +P G + +P P GP + A A
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 374 QLHAAMFAAPPTLPPPPALPASSLVLP-GHPADHELLRQELNTRFLVQSAERPGASLGP- 431
A P+ P PA++ P G PA + A P A P
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS-----------PKGAPTPPAVTPPS 1018
Query: 432 --GALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLP--------------------- 468
G+ F + T + + P P G P
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 469 -PTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFP------PAIPGLPTL--LPHPGPFG 519
PTPPAA PP K P SP + P P P G PT P P G
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 520 SL-----QGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVP---PGRPRGARDSRSLQKTW 571
L +GA + P ++T P +G P P P+G + S +
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLAT---PPPKGAPTTPAATPPSPKGGLATPSPKG-- 1193
Query: 572 VGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRP 631
AP +A+ S K G + K GA P
Sbjct: 1194 ---APTTPAATPPSPKGG----------------------LATPSPK---GAPTTPAATP 1225
Query: 632 PAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSR-PSTFG 690
P+P LA P P PA+ P P P + P G T P + PS G
Sbjct: 1226 PSP--------KGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 691 GLGSLSSHAFGGLGSHALAPGGSIF---APKEG---SSVHGLPSPHEAWNRLHRAPPSFP 744
GL + H AP ++ +PK G S G P+P A + P P
Sbjct: 1277 GLAT---------PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 745 AP----------PPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATP 794
P PP PK + A T + +E + PA
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPT--LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 795 AGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARA----------- 843
P G + S G +PA P+ K +P E A P++
Sbjct: 1386 PPSPKRGPAI--PSPKGDPTSPAVIPLSPK-KAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 844 --SPPHSKAAPGDVKVKEERGED--EASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFR 899
P + A G +G+ A PP+ PAP Q+ AP
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP-------- 1494
Query: 900 GLELPRRAFPAAAPAPGSAALL-----EPPERPYRDREPHGYSPERLRGELERARAPHLP 954
A PA AP A++ E P P R+P + L + AP
Sbjct: 1495 -------ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 955 PAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPA---AAALGAP-------PPLVT 1004
PA+ A+ P+ +PA + A +PPA + GAP PP VT
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPAT-PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606
Query: 1005 AAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPP 1040
+ P P PP + T P GP +PP
Sbjct: 1607 SPSPKEAPTPP-AVTPPSPEKGPATPAPKGTPTSPP 1641
Score = 59.7 bits (143), Expect = 1e-08
Identities = 228/1001 (22%), Positives = 305/1001 (30%), Gaps = 198/1001 (19%)
Query: 119 PRESETCP-----PAEPSENRRPLE--AGSPGQDLEPACDGARKVPLQPSKQMKVTVSKG 171
P+++ P PA PS P A P PA + P P+ KG
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP--KG 975
Query: 172 GDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKG 231
G ++ P S +G P + F G
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 232 PALE----KSEAKAGPVPKVSGLERSRELSAESFLPTASPA-PHAAPCPGPPPGSRANPL 286
PA K A P+PK + + L + P PA P P PP + +P
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPS----PKGGPATPSLKGAPTPPAATPPSPK 1091
Query: 287 VKKEPPAPHRHTPQPP---PPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPL 343
P+P + P PP PP P+G L T P GA + + GL+ + P
Sbjct: 1092 GGPATPSP-KGAPMPPAATPPSPKGGLAT--PPHKGAPTTPAATPPSPKGGLA--TPPPK 1146
Query: 344 GLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHP 403
G + +P P L+T PPP P + P P
Sbjct: 1147 GAPTTPAATPPSPKGGLAT------------------------PPPKGAPTTPAATPPSP 1182
Query: 404 ADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPF 463
+ + GA P A + P
Sbjct: 1183 KGG------------LATPSPKGAPTTPAATPPSP-----------------KGGLATPS 1213
Query: 464 PAGLPPTPPAAPP--------PFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP 515
P G P TP A PP P K AP +P S P+ PP G PT P
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPT--TPAATPPSPKGGPATPPP-KGAPT--PPA 1268
Query: 516 GPFGSLQG--AFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVG 573
SL+G A P P AVV + GP T P G P + K G
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP---ATSPPKGAPTPPAATPPSPKGSPG 1325
Query: 574 VAP---APLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGR 630
P AP ++ P + + + G
Sbjct: 1326 TPPPKGAPTPPAVTPPSP------------------KGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 631 PPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFG 690
P P H P P G A P+ P G P + +P P P + P T
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSP-AVIPLSPKKAP-ATPVTRE 1423
Query: 691 GLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWN-RLHRAPPSFPAPPPW 749
G + S G L A+ P AP + G +P + L P P PP
Sbjct: 1424 GAATPSK---GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480
Query: 750 PKSVDAER-----------VSALTNHDREPDNGKE-----EQERDLLEKTR-LLSRASPA 792
PK V + A T P + KE RD + T LLS+ +PA
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 793 TPAGHPVSGLLLRAQSELGRSGAPA-----EREAEPRVKESRSPAKEEAAKMPARASP-- 845
T A P L+ A + PA E A P KE+ SP + SP
Sbjct: 1541 TLA--PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 846 ---------PHSKAAPGDVKVKEERGEDEASEP-PAGGLHPAPLQLGLGRERLGAPGF-- 893
P K AP V E + P P G P+ ++ +P
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Query: 894 ----AWEPFRGLELPRRAFPAA------APAPGSAALLEPPER--PYRDRE--------P 933
A P LP + P A APAP S ++ P R P + P
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
Query: 934 HGYSPERLRGELER-ARAPHLP------------PAAPALDGALLPSLGALHFPRLSPAA 980
+ +G L A AP LP A+ + G L P P L+ AA
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP-LTAAA 1777
Query: 981 LHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTP 1021
L + +A +PP + A P P PP+ + P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP 1818
Score = 48.5 bits (114), Expect = 3e-05
Identities = 107/483 (22%), Positives = 154/483 (31%), Gaps = 41/483 (8%)
Query: 38 PEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALE 97
P +P GL P+GA P A PP + ++ + G +T +L+
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGPATPPPK----GAPTPPAATPPSLK 1275
Query: 98 KDMALKPHERKEKWERRLIKKPRESETCPPAE----PSENRRPLEAGSPGQDLEPACDGA 153
+A PH+ P+ P + P P GSPG P GA
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT---PPPKGA 1332
Query: 154 RKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPD 213
P K T + S +S P ++ S +G + P
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPK 1390
Query: 214 DKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAP-HAA 272
++ S K G PA+ K P V+ + + P +P A
Sbjct: 1391 RGPAIPSPK----GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 273 PCPGPPPGSRANPLVKKEPPAPHRHTPQPP-PPQPRGLLPTHVPASLGAFAGHSQAAANG 331
P P G A P K +P P P P PP P+ + + P A A + A
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK--APATPAPMGAPT 1504
Query: 332 LHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP--TLPPP 389
L + SS K V +P ++ + L + L PP T+P P
Sbjct: 1505 LPAVIPSSP------KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Query: 390 PALPA--SSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQ 447
PA + P P+ E T + A P L P A+ +
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618
Query: 448 HTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHS-SVSFFPSFPPAIP 506
T + T P P G P +PP P DSP S + + P A
Sbjct: 1619 VTPPSPEKGPAT--PAPKGTPTSPPVTPSSLK------DSPTSPASVTCKMGATVPQASK 1670
Query: 507 GLP 509
GLP
Sbjct: 1671 GLP 1673
Score = 47.8 bits (112), Expect = 5e-05
Identities = 111/537 (20%), Positives = 159/537 (29%), Gaps = 89/537 (16%)
Query: 38 PEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALE 97
P P G L+GAP P A PP + ++ + G + +T + +
Sbjct: 1065 PSPKGGPATPSLKGAP------TPPAATPPSPKGGPATPSPK----GAPMPPAATPPSPK 1114
Query: 98 KDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLE-PACDGARKV 156
+A PH+ P+ PP + + SP L P GA
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 157 PLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAH-AVSGRGYSCDSESG---- 211
P K ++ + + S + L+ S A + + S G
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 212 PDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVS-------GLERSRELSAESFLPT 264
P K + + P GPA K P P + GL A +
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPP--KGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 265 ASPAPHAAPCPGPPPGSRANPLVKKEPPA------PHRHTPQPP---PPQP--RGLLPTH 313
P+P P PP G+ P P P + P PP PP P LP
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 314 VPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQH 373
P+S G G S GP P +T H
Sbjct: 1353 TPSSKG--------------------------GPTTPSSKEGPTPPAAT--------PSH 1378
Query: 374 QLHAAMFAAP----PTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPG-AS 428
+ AM P +P P P S V+P P ++ T + A P
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP------KKAPATPVTREGAATPSKGD 1432
Query: 429 LGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPP-------FDKY 481
L P A+ + T PA PP+P P P K
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Query: 482 APKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP-GPFGSLQGAFQPKVSDPYRAVV 537
AP +P + + PS P +P P+ P P +L P P A++
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549
Score = 33.1 bits (74), Expect = 1.4
Identities = 194/851 (22%), Positives = 287/851 (33%), Gaps = 159/851 (18%)
Query: 228 TDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPA--PHAAPCPGPPPGSRANP 285
T+ PA E+ + P + + L S LS + L P P +P P P S AN
Sbjct: 6 TETVPATEQELPQ--PQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQ 63
Query: 286 LVKKEPPAPHRHTP-QPPPPQ-------PRGL---LPTHVPASLG------AFAGHSQAA 328
P+ TP + P PQ P G PT +P +G A A S
Sbjct: 64 ASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI 123
Query: 329 ANGLHGLSRSSSAPLGLGKHVSLSPHGP------GPHLSTSHLALRSQAQHQLHAAMFAA 382
A L G + SSSAPL L V+L+PH P+L TS ++ +
Sbjct: 124 APTLKG-TPSSSAPLAL---VALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179
Query: 383 PPTLPPPPALPASSLVLP---GHPADHELLRQE----LNTRFLVQSAERPGASLGPGALL 435
P+ P S V+P G P+ ++ + +QS P L
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239
Query: 436 RAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSV 495
Q + T + + Q+ P L P +PP + + P S
Sbjct: 240 AIASPQVKDTTISSVLISPQN-------PGSLSLKGPVSPPAALSLSTQ-SLPVVTSSQK 291
Query: 496 SFFPSFPPAIP---GLPTLLPHPGPFGSLQ--GAFQPK-VSDPYRAVVKV---STCWEGP 546
+ P+ PP P G H FGS+Q G P +SDP + V ST P
Sbjct: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP 351
Query: 547 WQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQ 606
Q R+++PP R + VA P+ A + + P ++ + +
Sbjct: 352 SQ-RSVIPPLPSRN-------EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL---- 399
Query: 607 QKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGP 666
L P L L P A +HYP P+ +NP
Sbjct: 400 NVATSFSLSP-----TTSLILKSSPNAT-----YHYPLVAQMPVSSVGTTPLVVTNPCTI 449
Query: 667 SAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGL 726
+A P + P P + G + ++ + L +AP APKE
Sbjct: 450 AAAPTTTFEVATCVSP---PMSSGPISNIEPTSPAAL---VMAP----VAPKE------- 492
Query: 727 PSPHEAWNRLHRAPPSFPAPPPWPKSVDAERV--SALTNHDREPDNGKEEQERDLLEKTR 784
PS A P PP P D + + S L K ++DL
Sbjct: 493 PSTQVA------TTLRIPVSPPLPDPEDLKNLPSSVLV---------KFPTQKDL----- 532
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARAS 844
+ PA+ G P S AQ+ L + +P V A + + + +S
Sbjct: 533 ---QTVPASLEGAPFS----PAQAGL-------TTKKDPTVLPLVQAAPKNSPSFQSTSS 578
Query: 845 PPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELP 904
P +P K+ GE PA + +PL + + +A G +
Sbjct: 579 SPEIPLSPEATLAKKSLGEPLPIGKPASSM-TSPLGVNSSASVIKTDSYA-----GPDSA 632
Query: 905 RRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDG-- 962
++ P AA P +P G +P +G + + A+P L+G
Sbjct: 633 GPLLKSSLITPTVAAF------PLESADPAGVAPTTAKG-----TSTYTTTASPFLEGTV 681
Query: 963 ALLP-----SLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRS 1017
+L P G L L P A N +A +P A PL T P P S
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA-----PLATLVLAPEIPKSVPS 736
Query: 1018 RTTPLGGLGPG 1028
+ P G PG
Sbjct: 737 PSLPPAGTPPG 747
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 75.9 bits (185), Expect = 2e-13
Identities = 86/342 (25%), Positives = 125/342 (36%), Gaps = 50/342 (14%)
Query: 4 KVRPSRRSRAQ-RDRGRRREAA-----RDARAQSPSSGDEPEPSPGKENAGLRGAPPRGA 57
K RP RSR++ R R R R + R R++S S PSP + + R PPR
Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
Query: 58 APAPRTAR---PPRRRRRESSSQEEEVIDGFAIASFSTLEALEK------------DMAL 102
P PR R P RRRRR S+S + S S + K +
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
Query: 103 KPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQD----LEPACDGARKVPL 158
P R+ + P+ + P + + R+ + SPG+ + R+ P
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
Query: 159 QPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKA-- 216
K KV +S+ + + ++ R + + S G S SE ++
Sbjct: 453 PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
Query: 217 ---SVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAP 273
VG + +P P+ K + + P R R + S PT +P
Sbjct: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSP--------RGRRRRSPSPPPTRR---RRSP 561
Query: 274 CPGPPPGSRANPLVKKEPPAPHRHTPQPPP----PQPRGLLP 311
P PPP R P P P R TP PPP P PR P
Sbjct: 562 SPAPPPRRRRTP-----TPPPRRRTPSPPPRRRSPSPRRYSP 598
Score = 47.8 bits (112), Expect = 5e-05
Identities = 81/327 (24%), Positives = 108/327 (33%), Gaps = 59/327 (18%)
Query: 6 RPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTAR 65
RP R + GRRR SPS P P ++ RG R +P P R
Sbjct: 506 RPKRSHVKNGEVGRRRR-------HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR 558
Query: 66 -------PPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKK 118
PPRRRR + T + + P +RR
Sbjct: 559 RSPSPAPPPRRRRTPTPPPRRR-----------TPSPPPRRRSPSPRRYSPPIQRRYSPS 607
Query: 119 P---RESETCPPA-------EPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTV 168
P R + + PP P RR + P Q P R+ P SK K +
Sbjct: 608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK--RRSPSLSSKHRKGSS 665
Query: 169 SKGGDRDSDDDSVLEATSS----RDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLF 224
R++ + S R P + SS V RG S S P + S
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR-RGAS----SSPQRRQSPSPSTRP 720
Query: 225 APGTDKGPALEKSEAKAGPVPK-VSGLERSRELSAESFLPTASPAPHAAPCPGPP-PGSR 282
+ P +K + A P P+ V + SR +S SP P A P PP P
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG-------SPEPAAKKPPAPPSPVQS 773
Query: 283 ANPLVKKEPPAPHRH----TPQPPPPQ 305
+P P P + TP P PP+
Sbjct: 774 QSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Score = 45.1 bits (105), Expect = 4e-04
Identities = 81/386 (20%), Positives = 124/386 (32%), Gaps = 99/386 (25%)
Query: 7 PSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARP 66
PS +++ ++R+ ++ A ++ + +E R R +P R +R
Sbjct: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRS 179
Query: 67 PRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCP 126
P RRR S + E + S +
Sbjct: 180 PSPRRRSSPVRRER---------------------------------------KRSHSRS 200
Query: 127 PAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATS 186
P +++R P PA + K P P +KV + SV EATS
Sbjct: 201 PRHRTKSRSP----------SPAPEKKEKTPELPEPSVKV----------KEPSVQEATS 240
Query: 187 SRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPK 246
+ D L + P+ K P +K EK + K P +
Sbjct: 241 TSDILKVPKPEPI------------PEPK---------EPSPEKNSKKEKEKEKTRPRSR 279
Query: 247 VSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTP---QPPP 303
RSR S S T H + P R +P + P+P R TP PPP
Sbjct: 280 SRSKSRSRTRS-RSPSHTRPRRRHRSRSRSYSPRRRPSP---RRRPSPRRRTPPRRMPPP 335
Query: 304 PQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTS 363
P+ R + P + S + ++ SRS S P K S P T
Sbjct: 336 PRHR---RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR------KTR 386
Query: 364 HLALRSQAQHQLHAAMFAAPPTLPPP 389
L+ + + H +PP PPP
Sbjct: 387 RLSPSASPPRRRHR---PSPPATPPP 409
Score = 39.7 bits (91), Expect = 0.015
Identities = 74/340 (21%), Positives = 107/340 (31%), Gaps = 72/340 (21%)
Query: 727 PSPHEAWNRLHRAPPSFPAPPPWPK--------------SVDAERVSALTNHDREPDNGK 772
PSP + R PP PPP + S+ S+ ++ R P
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
Query: 773 EEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPA 832
++ KTR LS ++ H S + P + P ++S
Sbjct: 375 PKRTSSPPRKTRRLSPSASPPRRRHRPSP----------PATPPPKTRHSPTPQQSNRTR 424
Query: 833 KEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPG 892
K + P R S KV + +G E E P+ P ++L E G
Sbjct: 425 KSRVSVSPGRTSG----------KVTKHKGT-EKRESPSPAPKPRKVELSESEEDKGGKM 473
Query: 893 FAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPH 952
A + + RR ++ GS++ E ERP R +G R R R+ +P
Sbjct: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSED-ERPKRSHVKNGEVGRRRRHSPSRSASP- 531
Query: 953 LPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP-PPLVTAAGPPTP 1011
SP T P +P PP P+P
Sbjct: 532 ------------------------SPRKRQK----ETSPRGRRRRSPSPPPTRRRRSPSP 563
Query: 1012 PGPPRSRTTPL------GGLGPGEARDYSPSRNPPEVEAR 1045
PPR R TP P R SP R P ++ R
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR 603
Score = 36.6 bits (83), Expect = 0.13
Identities = 62/271 (22%), Positives = 95/271 (35%), Gaps = 39/271 (14%)
Query: 783 TRLLSRASPATPAGH---PVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKM 839
TR SPA P P R S R +P+ R P ++ SP+ +
Sbjct: 555 TRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614
Query: 840 PARASPPHSKAAPGDVKVKEERGEDEASEPPAGGL--HPAPLQLGLGRERLGAPGFAWEP 897
+ PP +A+P S PP + P P Q + +P + +
Sbjct: 615 ASPPPPPKRRASP--------------SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
Query: 898 FRGLELPRRAFPAAAPAPGSAALLEP-PERPYRDREPHGYSPERLRG---ELERARAPHL 953
+G R A +P P P P P P P RG +R ++P
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP----PPVRRGASSSPQRRQSPS- 715
Query: 954 PPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPG 1013
P P + P + A+ + R + + G+P P A PP PP
Sbjct: 716 PSTRPIRRVSRTPEPKKIK----KAASPSPQSVRRVSSSRSVSGSPEP--AAKKPPAPPS 769
Query: 1014 PPRSRTTPLGGLGPG----EARDYSPSRNPP 1040
P +S+ +P P +A+ +PS +PP
Sbjct: 770 PVQSQ-SPSTNWSPAVPVKKAKSPTPSPSPP 799
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.7 bits (182), Expect = 4e-13
Identities = 234/1007 (23%), Positives = 325/1007 (32%), Gaps = 223/1007 (22%)
Query: 130 PSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVT------VSKGGDRDSDDDSVLE 183
P E R SPG + DG + Q +K+ +V V+K G + +S E
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESE 82
Query: 184 ATSSRD----------PLSDSSAHAVSGRGYSCDSESGP---DDKASVGSEKLFAPGTDK 230
T++ P S S ++ GR + D S P D S +++PG+ +
Sbjct: 83 ETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE 142
Query: 231 GPALEKSEAKAGPV----------PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPG 280
+ S GP P + + SF P S P P PP
Sbjct: 143 NDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT 202
Query: 281 SRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANG-------LH 333
SR + + P AP H PQ P G+L G A S NG
Sbjct: 203 SR---MFQAPPGAPPPH-PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTT 258
Query: 334 GLSRSSSA------------PLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFA 381
+S SSS P+G G S P PH++
Sbjct: 259 PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT-------------------- 298
Query: 382 APPTLPPPPAL-----------PASSLVLPGH-PADHELLRQELNTRFLVQSAERPGASL 429
P LPPPPAL + LPGH P+ H + + PG
Sbjct: 299 --PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG--------MGGLPPGPEK 348
Query: 430 GPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKY-------- 481
GP T AP P LPP +AP P ++
Sbjct: 349 GP---------------------------TLAPSPHSLPPASSSAPAPPMRFPYSSSSSS 381
Query: 482 -APKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQ-PKVSDPYRAVVKV 539
A S SS S FP+ A+P P P P SL + Q PK + P ++
Sbjct: 382 SAAASSSSSSSSSSASPFPA-SQALPSYPHSFPPP---TSLSVSNQPPKYTQP--SLPSQ 435
Query: 540 STCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIA 599
+ +GP PP P G R L + P P S G H ++
Sbjct: 436 AVWSQGP-------PPPPPYG----RLLANSNAHPGPFPPST-------GAQSTAHPPVS 477
Query: 600 WQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHP 659
+ HQQ+ ++ Q + + + PP PG F P G +
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFP------------HPLEGGSSH 525
Query: 660 ASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKE 719
++P+ S GS P P P + +S G G + S + +
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGPAHLPPPHS-----QVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 720 GSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQ---E 776
GS PSP + AP FP P P + A + + P K
Sbjct: 581 GSYPCSHPSPSQG---PQGAPYPFP-PVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636
Query: 777 RDLLEKTRLLSRASPATPAGH-PVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEE 835
++ ATP G+ P S R + G G A P + SP
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG--TSPPAGPGTFKPGSPTVGP 694
Query: 836 AAKMPARAS------PPHSKAAPGD----VKVKEERGED----EASEPPAGGLHPAPLQL 881
PA S PP + A G ++K+E E+ E+ PPA P P +
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVV 754
Query: 882 GLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGS------AALLEPPERPYRDREPHG 935
+ + F RG R+ P GS A L+E R R
Sbjct: 755 DVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
Query: 936 YSPERLR---GELERARAPHLPPAAP-ALDGAL---LPSLGAL-HFPRLSPAALHNGLLA 987
ER R E ER + L + A +G PSLG + H P P + +A
Sbjct: 815 KEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGS----AVA 870
Query: 988 RTPPAAAALGAPPPLVTAAGPPTPPG--PPRSRT----TPLGGLGPG 1028
PP LG P + P P +R PLG + PG
Sbjct: 871 TVPP---YLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPG 914
Score = 50.4 bits (119), Expect = 8e-06
Identities = 146/648 (22%), Positives = 200/648 (30%), Gaps = 129/648 (19%)
Query: 468 PPTPPAAPPPFDKYAPKLDSPYFRHSSVS----FFPSFPP------AIPGLPTLLPHPGP 517
PP P +P P D + ++ + H SV+ P PP A PG P PHP
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP--PHPQL 219
Query: 518 F-GSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAP 576
+ G G P S GP G+ PP P S +
Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSV--GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
Query: 577 APLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGV 636
P+ L P HV + + P L G P PG
Sbjct: 278 TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL---------GAQPLPG- 327
Query: 637 FAGFHYPQDLARPLFPSTGAAHPASNP-FGPSAHP----GSFLPTGPLTDPFSRPSTFGG 691
H P A P P PS H S P P+ P+S S+
Sbjct: 328 ----HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383
Query: 692 LGSLSSHAFGGLGS-----HALAPGGSIFAPKEGSSVHGLPS-------PHEA-WNRLHR 738
S SS + S AL F P SV P P +A W++
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443
Query: 739 APPSFPA--------PPPWPKSVDAER-----VSALTNHDREPDNGKEEQERDLLEKTRL 785
PP + P P+P S A+ VS +H ++ +++Q++ ++ +
Sbjct: 444 PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503
Query: 786 LSRASPATPAG--HPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARA 843
+ P P HP+ G + A P + PA
Sbjct: 504 HGNSGPPPPGAFPHPLEG--------------GSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 844 SPPHSK-----AAPGDVKVKEERGEDEA-SEPPAGGLHPAPLQLGLGRERLGAPGFAWEP 897
PPHS+ A P V + S+ HP+P Q G + GAP + + P
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ---GPQ--GAP-YPFPP 603
Query: 898 FRGLELPRRAFPAA----APAPGSAALLEPPERP-----------YRDREPHGY---SPE 939
+ A +P PP P Y+ P GY SP
Sbjct: 604 VPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPP 663
Query: 940 RLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP 999
R PPA P P++G P P+ L P+ P
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---------PSLP----P 710
Query: 1000 PPLVTAAGPP-----TPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEV 1042
PP A+GPP P TP + P AR SP PP+V
Sbjct: 711 PPAAPASGPPLSATQIKQEPAEEYETPESPVPP--ARSPSP---PPKV 753
Score = 43.9 bits (102), Expect = 8e-04
Identities = 77/294 (26%), Positives = 96/294 (32%), Gaps = 68/294 (23%)
Query: 235 EKSEAKAGPVPKVSGLERSRELSAESFLP----TASPAPHAAPCPGPPPGSRANPLVKKE 290
E+ K K LERS +L+ E P + P PH P + P + +
Sbjct: 820 EREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPD 879
Query: 291 PPA---------PHRHTPQ--------PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLH 333
PA PH +P P GLL +VPA + +
Sbjct: 880 TPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARE 939
Query: 334 GLSRSSSAPLGLGKHVSLSP-HG-PGPHLST--SHLALRSQAQHQLHAAMFAAPPTLPPP 389
R P K L P HG PGP L H L A+ PP L P
Sbjct: 940 RDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGL----------ALQPGPPGLHPF 989
Query: 390 PALPA------SSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEF---- 439
P P+ L L PA + Q AER A+LG L R +
Sbjct: 990 PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERV-AALGNDPLARLQMLNVT 1048
Query: 440 -HQHQHTHQHTHQHTHQHQHTFA---------------------PFPAGLPPTP 471
H HQH+H H+H H HQ A P+PAG P P
Sbjct: 1049 PHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNP 1102
Score = 35.4 bits (80), Expect = 0.28
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 815 APAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGL 874
A ERE E R ++ R K P+ P H PG G A +P GL
Sbjct: 929 AAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG--LALQPGPPGL 986
Query: 875 HPAPLQLGLG---RERLG-APGFAWEP 897
HP P LG RERL A G A P
Sbjct: 987 HPFPFHPSLGPLERERLALAAGPALRP 1013
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.7 bits (182), Expect = 4e-13
Identities = 234/1007 (23%), Positives = 325/1007 (32%), Gaps = 223/1007 (22%)
Query: 130 PSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVT------VSKGGDRDSDDDSVLE 183
P E R SPG + DG + Q +K+ +V V+K G + +S E
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESE 82
Query: 184 ATSSRD----------PLSDSSAHAVSGRGYSCDSESGP---DDKASVGSEKLFAPGTDK 230
T++ P S S ++ GR + D S P D S +++PG+ +
Sbjct: 83 ETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE 142
Query: 231 GPALEKSEAKAGPV----------PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPG 280
+ S GP P + + SF P S P P PP
Sbjct: 143 NDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT 202
Query: 281 SRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANG-------LH 333
SR + + P AP H PQ P G+L G A S NG
Sbjct: 203 SR---MFQAPPGAPPPH-PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTT 258
Query: 334 GLSRSSSA------------PLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFA 381
+S SSS P+G G S P PH++
Sbjct: 259 PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT-------------------- 298
Query: 382 APPTLPPPPAL-----------PASSLVLPGH-PADHELLRQELNTRFLVQSAERPGASL 429
P LPPPPAL + LPGH P+ H + + PG
Sbjct: 299 --PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG--------MGGLPPGPEK 348
Query: 430 GPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKY-------- 481
GP T AP P LPP +AP P ++
Sbjct: 349 GP---------------------------TLAPSPHSLPPASSSAPAPPMRFPYSSSSSS 381
Query: 482 -APKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQ-PKVSDPYRAVVKV 539
A S SS S FP+ A+P P P P SL + Q PK + P ++
Sbjct: 382 SAAASSSSSSSSSSASPFPA-SQALPSYPHSFPPP---TSLSVSNQPPKYTQP--SLPSQ 435
Query: 540 STCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIA 599
+ +GP PP P G R L + P P S G H ++
Sbjct: 436 AVWSQGP-------PPPPPYG----RLLANSNAHPGPFPPST-------GAQSTAHPPVS 477
Query: 600 WQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHP 659
+ HQQ+ ++ Q + + + PP PG F P G +
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFP------------HPLEGGSSH 525
Query: 660 ASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKE 719
++P+ S GS P P P + +S G G + S + +
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGPAHLPPPHS-----QVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 720 GSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQ---E 776
GS PSP + AP FP P P + A + + P K
Sbjct: 581 GSYPCSHPSPSQG---PQGAPYPFP-PVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636
Query: 777 RDLLEKTRLLSRASPATPAGH-PVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEE 835
++ ATP G+ P S R + G G A P + SP
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG--TSPPAGPGTFKPGSPTVGP 694
Query: 836 AAKMPARAS------PPHSKAAPGD----VKVKEERGED----EASEPPAGGLHPAPLQL 881
PA S PP + A G ++K+E E+ E+ PPA P P +
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVV 754
Query: 882 GLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGS------AALLEPPERPYRDREPHG 935
+ + F RG R+ P GS A L+E R R
Sbjct: 755 DVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
Query: 936 YSPERLR---GELERARAPHLPPAAP-ALDGAL---LPSLGAL-HFPRLSPAALHNGLLA 987
ER R E ER + L + A +G PSLG + H P P + +A
Sbjct: 815 KEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGS----AVA 870
Query: 988 RTPPAAAALGAPPPLVTAAGPPTPPG--PPRSRT----TPLGGLGPG 1028
PP LG P + P P +R PLG + PG
Sbjct: 871 TVPP---YLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPG 914
Score = 50.4 bits (119), Expect = 8e-06
Identities = 146/648 (22%), Positives = 200/648 (30%), Gaps = 129/648 (19%)
Query: 468 PPTPPAAPPPFDKYAPKLDSPYFRHSSVS----FFPSFPP------AIPGLPTLLPHPGP 517
PP P +P P D + ++ + H SV+ P PP A PG P PHP
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP--PHPQL 219
Query: 518 F-GSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAP 576
+ G G P S GP G+ PP P S +
Sbjct: 220 YPGGTGGVLSGPPMGPKGGGAASSV--GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
Query: 577 APLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGV 636
P+ L P HV + + P L G P PG
Sbjct: 278 TPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL---------GAQPLPG- 327
Query: 637 FAGFHYPQDLARPLFPSTGAAHPASNP-FGPSAHP----GSFLPTGPLTDPFSRPSTFGG 691
H P A P P PS H S P P+ P+S S+
Sbjct: 328 ----HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383
Query: 692 LGSLSSHAFGGLGS-----HALAPGGSIFAPKEGSSVHGLPS-------PHEA-WNRLHR 738
S SS + S AL F P SV P P +A W++
Sbjct: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443
Query: 739 APPSFPA--------PPPWPKSVDAER-----VSALTNHDREPDNGKEEQERDLLEKTRL 785
PP + P P+P S A+ VS +H ++ +++Q++ ++ +
Sbjct: 444 PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQH 503
Query: 786 LSRASPATPAG--HPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARA 843
+ P P HP+ G + A P + PA
Sbjct: 504 HGNSGPPPPGAFPHPLEG--------------GSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 844 SPPHSK-----AAPGDVKVKEERGEDEA-SEPPAGGLHPAPLQLGLGRERLGAPGFAWEP 897
PPHS+ A P V + S+ HP+P Q G + GAP + + P
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ---GPQ--GAP-YPFPP 603
Query: 898 FRGLELPRRAFPAA----APAPGSAALLEPPERP-----------YRDREPHGY---SPE 939
+ A +P PP P Y+ P GY SP
Sbjct: 604 VPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPP 663
Query: 940 RLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP 999
R PPA P P++G P P+ L P+ P
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---------PSLP----P 710
Query: 1000 PPLVTAAGPP-----TPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEV 1042
PP A+GPP P TP + P AR SP PP+V
Sbjct: 711 PPAAPASGPPLSATQIKQEPAEEYETPESPVPP--ARSPSP---PPKV 753
Score = 43.9 bits (102), Expect = 8e-04
Identities = 77/294 (26%), Positives = 96/294 (32%), Gaps = 68/294 (23%)
Query: 235 EKSEAKAGPVPKVSGLERSRELSAESFLP----TASPAPHAAPCPGPPPGSRANPLVKKE 290
E+ K K LERS +L+ E P + P PH P + P + +
Sbjct: 820 EREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPD 879
Query: 291 PPA---------PHRHTPQ--------PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLH 333
PA PH +P P GLL +VPA + +
Sbjct: 880 TPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARE 939
Query: 334 GLSRSSSAPLGLGKHVSLSP-HG-PGPHLST--SHLALRSQAQHQLHAAMFAAPPTLPPP 389
R P K L P HG PGP L H L A+ PP L P
Sbjct: 940 RDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGL----------ALQPGPPGLHPF 989
Query: 390 PALPA------SSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEF---- 439
P P+ L L PA + Q AER A+LG L R +
Sbjct: 990 PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERV-AALGNDPLARLQMLNVT 1048
Query: 440 -HQHQHTHQHTHQHTHQHQHTFA---------------------PFPAGLPPTP 471
H HQH+H H+H H HQ A P+PAG P P
Sbjct: 1049 PHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNP 1102
Score = 35.4 bits (80), Expect = 0.28
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 815 APAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGL 874
A ERE E R ++ R K P+ P H PG G A +P GL
Sbjct: 929 AAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG--LALQPGPPGL 986
Query: 875 HPAPLQLGLG---RERLG-APGFAWEP 897
HP P LG RERL A G A P
Sbjct: 987 HPFPFHPSLGPLERERLALAAGPALRP 1013
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 72.4 bits (176), Expect = 2e-12
Identities = 245/1082 (22%), Positives = 345/1082 (31%), Gaps = 223/1082 (20%)
Query: 8 SRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPP 67
++R +A+ R AAR +P P P P A LR GA R P
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-----GRKP 57
Query: 68 RRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPP 127
R I G I E P R +P S
Sbjct: 58 LAERAGG-------IGGATIP--------ESAPRAGPTRSAGTSSRNPASRPPASGRGER 102
Query: 128 AEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKV----TVSKGGDRDSDDDSVLE 183
A P++N P SPG+ A R PL K +++ TV++G ++ S L
Sbjct: 103 APPAKNTSPGPVSSPGR----ASGTTRPGPLG-QKGLRISAEETVARGKATEAPKRSALS 157
Query: 184 ATSSRD---PLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK 240
A + RD P + + A++ R + +E G A + G K + +
Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 241 AGPVPKV-------SGLER--SRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEP 291
P P GL+R SR LS+ S P +SPA R+ P + P
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSS-SATPLSSPA-------------RSGPSARGTP 263
Query: 292 PAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSL 351
AP H QP P + L P V R +AP +L
Sbjct: 264 RAP-AHPSQPKPKGLQALRPPQVTPP-------------------RKDAAP-------AL 296
Query: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQ 411
P P + S +++ A P TLPP P L + P P+ L
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL-- 354
Query: 412 ELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPP-- 469
Q+ P A+ P+ PP
Sbjct: 355 --------QTLPSPPATP----------------------------------PSQAPPSM 372
Query: 470 -TPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPK 528
TPP PP + P + P+ S P P A+ L P +LQ
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP--TLQATHSFL 430
Query: 529 VSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGA-RDSRSLQKTWVGVAPAPLSASI---L 584
P + +L P RP DS LQ A PL S+ +
Sbjct: 431 TMSPRQTQA-------------SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 585 SQKPGRWCAVHVQIAWQIYRH--QQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHY 642
S +Q + H Q + + + P + + PPA
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537
Query: 643 PQDLARPLFPSTGAAHPASNPF-----GPSAHPGSFLPTGPLTDPFSRPSTFG-----GL 692
LA P P A+ P + P P+ P P+ T P PS+
Sbjct: 538 LPSLAPP--PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
Query: 693 GSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKS 752
+L+S GL S L+P + P + LP P +A +PP P P P++
Sbjct: 596 PALASPPLQGLPSPPLSPLAT--PPPQAPPXLALP-PLQAPPSPPASPPLSPLATPSPQA 652
Query: 753 VDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGR 812
+A V L P + + + PA+P P + +A L
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQ-----------APFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 813 S--GAPAEREAEPRVKESRSPAKEEAAKMPA---------RASPPHSKAAPGDVKVKEER 861
P A P + S +P + + A ASPP S +A +V
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761
Query: 862 GEDEASEPPAGGLHPAPLQLG-LGRERLGA-PGFAWEPFRGLELPRRAFPAAAPAPGSAA 919
PP+ PA L + L + A P A P + L P +FP AP SA+
Sbjct: 762 AAPPLQVPPS---PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 920 LLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPA 979
L P P P +P L L + P PPA+P L PR P
Sbjct: 819 L---PMSPLATPPPQ--APPVLAAPL--LQVPPSPPASPTLQA-----------PRRPPT 860
Query: 980 ALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNP 1039
P + P L A P PP P RS ++ L GP A S + +
Sbjct: 861 -----------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATST 907
Query: 1040 PE 1041
PE
Sbjct: 908 PE 909
Score = 67.8 bits (164), Expect = 5e-11
Identities = 229/946 (24%), Positives = 305/946 (32%), Gaps = 135/946 (14%)
Query: 33 SSGDEPEPSPGKENAGLRGAPPRGAAPAP--------RTARP-PRRRRRESSSQEEEVID 83
+S P P G R P + +P P T RP P ++ S EE V
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 84 GFAIAS--FSTLEALEKDMALKPHE--------RKEKWERRLIKKPRESETCPPAEPSEN 133
G A + S L A + P R+ + + PR + + P P+E
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
Query: 134 -RRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLS 192
R+ + + S EP+ AR+ P S GG L +SS PLS
Sbjct: 205 PRKSVSSASEHSTTEPS-PAARRRP-----------SAGGGLQRPASRSL--SSSATPLS 250
Query: 193 DSSAHAVSGRGY----SCDSESGPDDKASVGSEKLFAPGTDKGPAL-----------EKS 237
+ S RG + S+ P ++ ++ P D PAL S
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 238 EAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP--APH 295
KA PVP + P A+P P A P P PP + P PP AP
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 296 RHT--PQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSP 353
T P PP + + P VP SL + + + + L L ++S LG SP
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS--LG-------SP 421
Query: 354 HGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPP---PPALPAS--------------S 396
H + ++QA + + PP PP P +LPAS S
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481
Query: 397 LVLPGHP-------ADH-------ELLRQELNTR--FLVQSAERPGASLGPGALLRAEFH 440
L HP A H L+ L T+ S + P ASL L
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541
Query: 441 QHQHTHQHTHQHTHQHQHT---FAPFPAGLPPTPPAAPPPFDKYA----PKLDSPYFRHS 493
+ T H T AP P PP+P PPP + P P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Query: 494 SVSFFPSFPPAIPGLPTLLPHPGP---FGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGR 550
+ PS PP P L T P P LQ P S P + S
Sbjct: 602 PLQGLPS-PPLSP-LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 551 TLVPPGRPRGARDSRSLQKTWVGVAPAPLSASIL--SQKPGRWCAVHVQIAWQIYRHQQK 608
L P P S +Q + A P+S S SQ P A +Q+
Sbjct: 660 LLQAPFSP---PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 609 IKEMQLDPHKLE--VGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPS----TGAAHPASN 662
P L + PPA + P PL + + PAS
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 663 PFGPSAHPGSFLPTGPLTDPF----SRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPK 718
P P A P P T P S P++F G S A L LA P
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA--SLPMSPLATPPPQAPPV 834
Query: 719 EGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERD 778
+ + +P A L +AP P P P SV R++ P +
Sbjct: 835 LAAPLLQVPPSPPASPTL-QAPRRPPTPGP-DTSVSGPRLTLALAPGPPPPPSRSPS--S 890
Query: 779 LLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAP-AEREAEPRVKESRSPAKEEAA 837
L L +S AT + G + S P AE A SR PA A
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
Query: 838 KMPARASPPHSKA-----APGDVKVKEERGEDEASEPPAGGLHPAP 878
+ A P A A G + E G + A+ P G L P P
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT-PAPGALDPGP 995
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 65.9 bits (159), Expect = 2e-10
Identities = 145/550 (26%), Positives = 189/550 (34%), Gaps = 119/550 (21%)
Query: 31 SPSSGDEPEPSPGKENAGLRGAPPRGAAPAP--------RTARP-PRRRRRESSSQEEEV 81
+P +G P G R P + +P P T RP P ++ S EE V
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 82 IDGFAIAS--FSTLEALEKDMALKPHE--------RKEKWERRLIKKPRESETCPPAEPS 131
G A + S L A + P R+ + + PR + + P P+
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 132 EN-RRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDP 190
E R+ + + S EP+ AR+ P S GG L +SS P
Sbjct: 194 EGPRKSVSSASEHSTTEPS-PAARRRP-----------SAGGGLQRPASRSL--SSSATP 239
Query: 191 LSDSSAHAVSGRGY----SCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPK 246
LS + S RG + S+ P ++ ++ P D PAL GP+
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL-------GPL-- 290
Query: 247 VSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP-------------A 293
S P A+P+P A P P PP + P PP A
Sbjct: 291 -------------SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 294 PHRHTPQPP-------PPQPRGLL-------PTHVPAS--LGAFAGHSQAAANGL--HGL 335
H P PP PPQ L P PAS L A S A N L H L
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 336 SRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPAS 395
S P SP P +S S SQA L A PP+ PP + P S
Sbjct: 398 QAPFSPPPSPPVQAPFSPPA-SPPVSPSATP-PSQAPPSLAAPPLQVPPS--PPASPPMS 453
Query: 396 SLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQ 455
P A L L Q A+ P + P AL + +
Sbjct: 454 PSATPPPQAPPPLAAPPL------QLAKPPPQA--PPALATPPLQALP-----SPPASFP 500
Query: 456 HQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGL--PTLLP 513
Q F+P A LP +P A PPP + P L +P + P PPA P L P P
Sbjct: 501 GQAPFSP-SASLPMSPLATPPP--QAPPVLAAPLLQ------VPPSPPASPTLQAPRRPP 551
Query: 514 HPGPFGSLQG 523
PGP S+ G
Sbjct: 552 TPGPDTSVSG 561
Score = 63.5 bits (153), Expect = 1e-09
Identities = 180/767 (23%), Positives = 253/767 (32%), Gaps = 129/767 (16%)
Query: 8 SRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPP 67
++R +A+ R AAR +P P P P A LR GA R P
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-----GRKP 57
Query: 68 RRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRES--ETC 125
R I G I P R + P E
Sbjct: 58 LAERAGG-------IGGATI----------------PESAPRAGPTRTSRPPASGRGERA 94
Query: 126 PPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKV----TVSKGGDRDSDDDSV 181
PPA+ N P SPG+ A R PL K +++ TV++G ++ S
Sbjct: 95 PPAK---NTSPGPVSSPGR----ASGTTRPGPLG-QKGLRISAEETVARGKATEAPKRSA 146
Query: 182 LEATSSRD---PLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSE 238
L A + RD P + + A++ R + +E G A + G K +
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206
Query: 239 AKAGPVPKV-------SGLER--SRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKK 289
+ P P GL+R SR LS+ S P +SPA + P P + A+P K
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSS-SATPLSSPA-RSGPSARGTPRAPAHPSQPK 264
Query: 290 EPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHV 349
PQ PP+ + P P S A S +A S SAP L + +
Sbjct: 265 PKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSAPP-------SPSAPPSL-QTL 315
Query: 350 SLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSL----VLPGHPAD 405
P P +TS + QA H + +P PPP A PA +L P PA
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 406 HELLRQELNTRFLVQSAERPGA----------SLGPGALLRAEFHQHQHTH-QHTHQHTH 454
L + S + P A S P ++A F +
Sbjct: 376 PPL------SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Query: 455 QHQHTFAPFPAGLPPTPPAAPP------PFDKYAPKLDSPYFRHSSVSFFPSFPP----- 503
Q + A P +PP+PPA+PP P + P L +P + + P PP
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP--PQAPPALATP 487
Query: 504 ---AIPGLPTLLPHPGPFG-SLQGAFQPKVSDPYRA----VVKVSTCWEGPWQGRTLVPP 555
A+P P P PF S P + P +A + P TL P
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547
Query: 556 GRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLD 615
RP S+ + +A AP S+ P + + H +
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-----GPDLAGHSSSATSTPEE 602
Query: 616 PHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP 675
+ G + PP A H P+ + PA P PG+ LP
Sbjct: 603 LRGYDSGPEGGAAASPPPDAELAACH----------PAAWSRGPAP-PLAFRGAPGAPLP 651
Query: 676 TGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSS 722
P T P S G + + G S APG P G+S
Sbjct: 652 WPPATGPGSAD------GLCTIYETEGPESATPAPGALDPGPSPGTS 692
Score = 61.2 bits (147), Expect = 5e-09
Identities = 125/492 (25%), Positives = 160/492 (32%), Gaps = 87/492 (17%)
Query: 616 PHKLEVGAKLDLFGRPPAP---GVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGS 672
P L V GR P G G P+ + P T + P ++ G A P
Sbjct: 41 PAALRVLGAAGAVGRKPLAERAGGIGGATIPE--SAPRAGPTRTSRPPASGRGERAPPAK 98
Query: 673 FLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGS----------- 721
GP++ P R S G L +A G + APK +
Sbjct: 99 NTSPGPVSSP-GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 722 SVHGLPSPHEAWNRLHRAP--------PSFPAPPPWPKSVDAERVSALTNH---DREPDN 770
G PSP A R RA P+ A P P + VS+ + H + P
Sbjct: 158 PTPGTPSP--AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215
Query: 771 GKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRS 830
+ L++ S +S ATP P RSG A S+
Sbjct: 216 RRRPSAGGGLQRPASRSLSSSATPLSSPA------------RSGPSARGTPRAPAHPSQP 263
Query: 831 PAKEEAAKMPARASPPHSKAAPG-------DVKVKEERGEDEASEPPAGGLHPAP----- 878
K A P + +PP AAP + S PP+ P+P
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323
Query: 879 --LQLGLGRERLGAPG--FAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRD--RE 932
LG L A P L P P A P A PP P
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383
Query: 933 PHGYSPERLRGELERA----------RAPHLPPAAPALDGALLP------SLGA--LHFP 974
P +P L L +A +AP PPA+P + + P SL A L P
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443
Query: 975 RLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLG------PG 1028
PA+ A PP A A PPL A P P PP T PL L PG
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPG 501
Query: 1029 EARDYSPSRNPP 1040
+A +SPS + P
Sbjct: 502 QA-PFSPSASLP 512
Score = 60.5 bits (145), Expect = 8e-09
Identities = 104/396 (26%), Positives = 137/396 (34%), Gaps = 86/396 (21%)
Query: 649 PLFPSTGAAHPASNPFGPSAHPG-SFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHA 707
PL S A S P PSA P LP+ P T P ++ G ++H+F L S
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF--LPSPP 346
Query: 708 LAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDRE 767
L+P + P + LP +APPS PA PP +S L +
Sbjct: 347 LSPLAT--PPPQAPPALALPPL--------QAPPSPPASPP---------LSPLATPSPQ 387
Query: 768 PDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKE 827
N L +A + P PV AP A P V
Sbjct: 388 APNALAVH----------LLQAPFSPPPSPPVQ--------------APFSPPASPPVSP 423
Query: 828 SRSPAKEEAAKMPARASPPHS--KAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGR 885
S +P + P+ A+PP + P + + PP L PLQL
Sbjct: 424 SATPPSQAP---PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP---LAAPPLQLAKPP 477
Query: 886 ERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGEL 945
+ P A P + L P +FP AP SA+L P P P +P L L
Sbjct: 478 PQ-APPALATPPLQALPSPPASFPGQAPFSPSASL---PMSPLATPPPQ--APPVLAAPL 531
Query: 946 ERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTA 1005
+ P PPA+P L PR P P + P L A
Sbjct: 532 --LQVPPSPPASPTLQA-----------PRRPPT-----------PGPDTSVSGPRLTLA 567
Query: 1006 AGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPE 1041
P PP P RS ++ L GP A S + + PE
Sbjct: 568 LAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPE 601
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 65.5 bits (158), Expect = 3e-10
Identities = 183/790 (23%), Positives = 251/790 (31%), Gaps = 136/790 (17%)
Query: 8 SRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPP 67
++R +A+ R AAR +P P P P A LR GA R P
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-----GRKP 57
Query: 68 RRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPP 127
R I G I E P R +P S
Sbjct: 58 LAERAGG-------IGGATIP--------ESAPRAGPTRSAGTSSRNPASRPPASGRGER 102
Query: 128 AEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKV----TVSKGGDRDSDDDSVLE 183
A P++N P SPG+ A R PL K +++ TV++G ++ S L
Sbjct: 103 APPAKNTSPGPVSSPGR----ASGTTRPGPLG-QKGLRISAEETVARGKATEAPKRSALS 157
Query: 184 ATSSRD---PLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK 240
A + RD P + + A++ R + +E G A + G K + +
Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 241 AGPVPKV-------SGLER--SRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEP 291
P P GL+R SR LS+ S P +SPA + P P + A+P K
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSS-SATPLSSPA-RSGPSARGTPRAPAHPSQPKPK 275
Query: 292 PAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAA------NGLHGLSRSSSAPLGL 345
PQ PP+ + P P S A S +AA L SSS L
Sbjct: 276 GLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334
Query: 346 GKHVSLSPHGPG-------------------------PHLSTSHLALRSQAQHQLHAAMF 380
+ L+P P P L +H L S L
Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394
Query: 381 AAPPTL--------PPPPALPA-SSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGP 431
APP L P PPA P S L P A + L L F + A P
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454
Query: 432 GALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPP------PFDKYAPKL 485
A + Q + A P +PP+PPA+PP P + P L
Sbjct: 455 PA---------SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 486 DSPYFRHSSVSFFPSFPP--------AIPGLPTLLPHPGPFG-SLQGAFQPKVSDPYRA- 535
+P + + P PP A+P P P PF S P + P +A
Sbjct: 506 AAPPLQLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 536 ---VVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWC 592
+ P TL P RP S+ + +A AP S+ P
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 593 AVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFP 652
+ + H + + G + PP A H P
Sbjct: 624 S-----GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH----------P 668
Query: 653 STGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGG 712
+ + PA P PG+ LP P T P S G + + G S APG
Sbjct: 669 AAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSAD------GLCTIYETEGPESATPAPGA 721
Query: 713 SIFAPKEGSS 722
P G+S
Sbjct: 722 LDPGPSPGTS 731
Score = 61.2 bits (147), Expect = 5e-09
Identities = 193/782 (24%), Positives = 253/782 (32%), Gaps = 177/782 (22%)
Query: 279 PGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAA-ANGLHGLSR 337
P +RA L+ PP +P+PPPP L V + GA A A G+ G +
Sbjct: 17 PAARAPGLLTPRPPG----SPRPPPPVTPAAL--RVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 338 SSSAP-LGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP---TLPPPPALP 393
SAP G + S P S R APP T P P + P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGER-------------APPAKNTSPGPVSSP 117
Query: 394 --ASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQ 451
AS PG L T ++ E P S AL T
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS----ALSAGARRDTSGPTPGTPS 173
Query: 452 HTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTL 511
+ A GLP P+A P P + P SS S + P+ P
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARP-----RPPTEGPRKSVSSASEHSTTEPS----PAA 224
Query: 512 LPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPG-----RPRGARDSRS 566
P G LQ +S A S GP T P +P+G + R
Sbjct: 225 RRRPSAGGGLQRPASRSLSSS--ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 567 LQKT--WVGVAPA--PLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVG 622
Q T APA PLS+S L+ P A+ Q + PH +
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLAT-PSPSAALQSQAP----------PTLPATPHSSSLT 331
Query: 623 AKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPG-SFLPTGPLTD 681
+L A PL P + P PSA P LP+ P T
Sbjct: 332 CQL---------------------ATPL--------PLAPP-SPSAPPSLQTLPSPPATP 361
Query: 682 PFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPP 741
P ++ G ++H+F L S L+P + P + LP +APP
Sbjct: 362 PSQATTSLGSPTLQATHSF--LPSPPLSPLAT--PPPQAPPALALPPL--------QAPP 409
Query: 742 SFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSG 801
S PA PP +S L + N L +A + P PV
Sbjct: 410 SPPASPP---------LSPLATPSPQAPNALAVH----------LLQAPFSPPPSPPVQ- 449
Query: 802 LLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHS--KAAPGDVKVKE 859
AP A P V S +P + P+ A+PP + P +
Sbjct: 450 -------------APFSPPASPPVSPSATPPSQAP---PSLAAPPLQVPPSPPASPPMSP 493
Query: 860 ERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAA 919
+ PP L PLQL + P A P + L P +FP AP SA+
Sbjct: 494 SATPPPQAPPP---LAAPPLQLAKPPPQ-APPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 920 LLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPA 979
L P P P +P L L + P PPA+P L PR P
Sbjct: 550 L---PMSPLATPPPQ--APPVLAAPL--LQVPPSPPASPTLQA-----------PRRPPT 591
Query: 980 ALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNP 1039
P + P L A P PP P RS ++ L GP A S + +
Sbjct: 592 -----------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATST 638
Query: 1040 PE 1041
PE
Sbjct: 639 PE 640
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 61.6 bits (148), Expect = 4e-09
Identities = 219/1004 (21%), Positives = 305/1004 (30%), Gaps = 186/1004 (18%)
Query: 27 ARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRRRESSSQEEEVIDGFA 86
+R P GD P P +G P G + + P E + +
Sbjct: 370 SRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP------GPLQCEAKPLGKAG 423
Query: 87 IASFSTLEA-LEKDMALKPHERKEKWERRLIKKPRESETCPPAEPS-------------- 131
+ LEA L ++M L P E L P ES T PP E S
Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPE----ESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479
Query: 132 ----ENRRPLEAG--SPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEAT 185
RPLE SP + P P P ++ ++ + ++ L
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539
Query: 186 SSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVG---SEKLFAPGTDKGPALEKSEAK-- 240
PLS + S P + + + E +P ++ P EA
Sbjct: 540 PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599
Query: 241 --------AGPVPKVSGLERSRELSAESFLP---TASPAPHAAPCPGPPPGSRANPL--- 286
P P+ S L E S S P SP P +P PP SR +PL
Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659
Query: 287 VKKEPP-------APHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAA---ANGLHGLS 336
+ PP P +P PPP+ L P + S A+ + L L
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP 719
Query: 337 RSSSAPLGLGKHVSLSPHGPGPHLS----TSHLALRSQAQHQLHAAMFAAPPTLPPPPAL 392
S L L + L P GPHLS HL+ R + + H + A P L P P
Sbjct: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE---EPHLSPQAEEPHLSPQPEE 776
Query: 393 PASSLVLPGHP-----ADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTH- 446
P V P P A+ L + L E P S P + + H
Sbjct: 777 PCLCAV-PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 447 -----------QHTHQHTHQHQHTFAPFPAGLPPTP---------PAAPPPFD-KYAPKL 485
+ +H + +P P P P P PPP + +P L
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
Query: 486 DSPYFRHSSVSFFPSFPPAIP----GLPTLLPH-------PGPFGSLQGAFQPKVSDP-- 532
P P +P G P+L P P P + A P P
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLG 955
Query: 533 ---YRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPG 589
Y K + E P L P P + P P+ IL PG
Sbjct: 956 ELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTD---------PEPVPPMILPPSPG 1006
Query: 590 RWCAVHVQIAWQ--------IYRHQ---QKIKEMQLDPH--KLEVGAKLDLFGRPPAPGV 636
I + + +H Q Q P L V + L G+
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066
Query: 637 FAGFH--YPQDLARPLFPS--TGAAHPASNPFG----PSAHPGSFL-----------PTG 677
A H + ++ P P+ A P +P G P+ P L P
Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLD 1126
Query: 678 PLTDPFSRPSTFGGLGSLSSHAFGG---LGSHALAPGGSIFAPKEGSSVHGLPSPHEAWN 734
+ P S+P GSL+S G L LAP + E G SP E
Sbjct: 1127 GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQE 1186
Query: 735 RLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATP 794
RAP + P PP KS +S L+ D + P
Sbjct: 1187 E-PRAPVA-PTPPTLIKSDIVNEISNLSQGDASAS----------------FPGSEPLLG 1228
Query: 795 AGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKA---- 850
+ P G L + + +PA E R+ P +++ A + KA
Sbjct: 1229 SPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEK 1288
Query: 851 -----APGDVKVKEERGED-EASEPPAGGLHPAPLQLGLGRERL 888
+P ++K+ R P GG H G GR RL
Sbjct: 1289 GRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGG---RGRGRARL 1329
Score = 57.8 bits (138), Expect = 5e-08
Identities = 200/878 (22%), Positives = 288/878 (32%), Gaps = 220/878 (25%)
Query: 263 PTASPAPHAAPCPGPPP--GSRANPLVKKE------PPAPHRHTPQPPPPQPRGLLPT-- 312
PT P P P PP G+ + P + PP RH P P P + P+
Sbjct: 2194 PTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD 2253
Query: 313 --HVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQ 370
VP S G G +S PL LSP P S AL +
Sbjct: 2254 NLAVPESPGVGGG--------------KASEPL-------LSP----PPFGESRKALEVK 2288
Query: 371 AQHQLHAAMFAAPPTLPPPPALPASSLVLPG-HPADHELLRQELNTRFLVQSAERPGASL 429
+ ++ PP L + P+S L G ++ + L R + PG L
Sbjct: 2289 KEELGASSPSYGPPNLGFVDS-PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
Query: 430 GP-----GALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPP----FDK 480
P L H + Q P P PP A PP D
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Query: 481 YAPKLDSPYFRHSSVS-----------FFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKV 529
++ SP + SS S F PS P P + P+ P +P+
Sbjct: 2408 FSRVPASPQSQSSSQSPLTPRPLSAEAFCPS--PVTPRFQSPDPYSRP------PSRPQS 2459
Query: 530 SDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAP----------L 579
DP+ + K P P A + SL T +G P L
Sbjct: 2460 RDPFAPLHKPPR-------------PQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL 2506
Query: 580 SASILS-------QKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPP 632
A + S + PG V + + Q + E L P + G PP
Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVGTPSPMR-FTFPQAVGEPSLKPPVPQPGL-------PP 2558
Query: 633 APGVFAGFHYPQDLARPLFPS----TGAAHPASNPFGPSA-HPGSFLPTGPLTDPFSRPS 687
G+ + F L +P + TG HP+ +P GPS+ G PL P P
Sbjct: 2559 PHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPP 2618
Query: 688 TFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVH-GLPSPHEAWNRLHRAPPSFPAP 746
AP GS+ G+S G+ SP E S A
Sbjct: 2619 P--------------------APDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658
Query: 747 PPWPKSVDAERVSALTNHDREPDNGKEEQERDLL------------EKTRLLSRASPATP 794
P + D +S L+ + E + ++ R+LL EK + A P
Sbjct: 2659 AELPGTQDPG-MSGLSQTELEKQR-QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGP 2716
Query: 795 AGH-------PVSGLLLRAQSELGRS-------GAPAEREAEPRVKESRSPAKEEAAKMP 840
G P L R Q+ + G P + + P + P+ + ++ P
Sbjct: 2717 PGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPP 2776
Query: 841 ARASPP----------------HSKAA-PGDVKVKEERGE----DEASEPPA-----GGL 874
A+P + +A PG + +++++ + +A+ +
Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSAR 2836
Query: 875 HPAPLQLGLGRERLGAP--GFAWE-PFRGLELPRRAFPA----------------AAPAP 915
P+ LGR+ LG+P G + P G +P A PA P P
Sbjct: 2837 FPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFP 2896
Query: 916 GSAALLEPPERPYR---DREPHGYSPERLRGELERARAPHLP--PAAPALDGALLPSLGA 970
G PP+RP +PH +PE LRG P P P AP L+ +L P+
Sbjct: 2897 GQG----PPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT--- 2949
Query: 971 LHFPRLSPAALHNGL-LARTPPAAAALGAPPPLVTAAG 1007
P L GL L PP++ LG P PL AG
Sbjct: 2950 ---PHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAG 2984
Score = 50.4 bits (119), Expect = 8e-06
Identities = 154/643 (23%), Positives = 208/643 (32%), Gaps = 140/643 (21%)
Query: 119 PRESETCPPAEP---SENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRD 175
P S T PA+P + RP AG PG+ R P P +K +
Sbjct: 2198 PYPSPTGAPAQPPMLGASSRP-GAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLA 2256
Query: 176 SDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKL-FAPGTDKGPAL 234
+ + + +PL S + E S G L F G L
Sbjct: 2257 VPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHL 2316
Query: 235 EKSEAKAGPVPKVSGLERSRELSAES---FLPTASPAPHAAPCPGPP-------PGSRAN 284
E K V K R+ ++ +S L P P A P PP PGS +
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 285 PLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLG 344
P +PP R PQPPPP+ LP P SL + A+ S+S P
Sbjct: 2377 PYA--QPPLTPR--PQPPPPESCCALP---PRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Query: 345 LGKHVSLSPHGPGPHLSTSHLALRSQAQHQLH---AAMFAAPPTLPPPPALPASSL---- 397
L + P P + R ++ Q A + P PP A A SL
Sbjct: 2430 LSAE-AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488
Query: 398 --------VLPGHPADHELLRQELNTRFLVQSAERP--------GASLGPGALLRAEFHQ 441
LP PA EL+ + V S + P GA +G + +R F Q
Sbjct: 2489 LGAGGFPAALPAGPAG------ELHAK--VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQ 2540
Query: 442 HQHTHQHTHQHTHQHQHTFAPFPAGLPPTP-PAAPPPFDKYA-----PKLDSPYFRHSSV 495
P+ PP P P PPP + P L P + +V
Sbjct: 2541 ------------------AVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTV 2582
Query: 496 ---SFFPSFPPAIP---------GL-----PTLLPHPGPFGSLQGAFQPKVSDPYRAVVK 538
+F PS P P GL P++LP P P GSL PY +
Sbjct: 2583 ATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSL----------PYLS--- 2629
Query: 539 VSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASIL-SQKPGRWCAVHVQ 597
G Q + P R + G+ + +A + +Q PG +
Sbjct: 2630 -----HGASQRSGITSPVEKR--------EDPGTGMGSSLATAELPGTQDPGMSGLSQTE 2676
Query: 598 IAWQIYRH-------QQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPL 650
+ Q R +Q+I+ L K A G P + G + L+R
Sbjct: 2677 LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQ 2736
Query: 651 FPSTGAAH-------PASNPFGPSAHPGSFLPTGPLTDPFSRP 686
P G P S GP PGSF P D SRP
Sbjct: 2737 TPFAGTQDKSSLVGLPPSKLSGPILGPGSF----PSDDRLSRP 2775
Score = 44.7 bits (104), Expect = 5e-04
Identities = 123/484 (25%), Positives = 161/484 (33%), Gaps = 115/484 (23%)
Query: 626 DLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFG--PSAHPGSFLPTGPLTDPF 683
D F +PPA G G P +L L P A P+ +PFG P+ PT P T P
Sbjct: 2140 DGFLKPPA-GSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP- 2197
Query: 684 SRPSTFGG------LGSLSSHAFGGLGSHALAPGGSI---------FAPKEGSSVHGLPS 728
PS G LG+ S G G P G+ F S+ L
Sbjct: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV 2257
Query: 729 PHEAWNRLHRAPPSFPAPPPWPKS-----VDAERVSALTNHDREPD-------------N 770
P +A +PPP+ +S V E + A + P+
Sbjct: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
Query: 771 GKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQS---------------ELGRSGA 815
G E + D+ K L RAS P GL LR Q ++ R G+
Sbjct: 2318 GLELKTPDVF-KAPLTPRASQVEPQS---PGLGLRPQEPPPAQALAPSPPSHPDIFRPGS 2373
Query: 816 PAEREAEPRVK-ESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGL 874
+ A+P + + P E +P R+ P D S PA
Sbjct: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLP-----------------SDPFSRVPASPQ 2416
Query: 875 HPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPH 934
+ Q L L A F P PR +P P S PP RP + R+P
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVT----PR----FQSPDPYS----RPPSRP-QSRDP- 2462
Query: 935 GYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAA----LHNGL----- 985
++P L + P P A SLGA FP PA LH +
Sbjct: 2463 -FAP------LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP 2515
Query: 986 --LARTPPAAAALGAPPPL----VTAAGPPT--PPGPPRSRTTPLG---GLGPGEARDYS 1034
R+P A +G P P+ A G P+ PP P P G GPG
Sbjct: 2516 PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
Query: 1035 PSRN 1038
S N
Sbjct: 2576 QSTN 2579
Score = 43.5 bits (101), Expect = 0.001
Identities = 109/414 (26%), Positives = 138/414 (33%), Gaps = 68/414 (16%)
Query: 646 LARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTD-PFSRPSTFGGLGSLSSHAFGGLG 704
L+RPL S + P +P P P P PL + P S P +L +
Sbjct: 485 LSRPLEESPLSPPPEESPLSP---PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
Query: 705 SHALAPGGSIFAPKEGSSVHGLP-----SPHEAWNRLHRAPPSFPAPPP---WPKSVDAE 756
+ L+P P E S + P SP +RL P P PP P S E
Sbjct: 542 ASPLSP------PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 757 RVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPA---TPAGHPVSGLLLRAQSELGR- 812
+ P + E+ L SR SP +P P + E+ R
Sbjct: 596 ASRLFPPFEESPLSPPPEESP--LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Query: 813 SGAPAEREAEPRVKES-RSPAKEEAAKMP----ARASPPHSKAAPGDVKVKEERGEDEAS 867
S P P +ES SP EE+ P +R SPP P D + AS
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP-----PEDSPTSPPPEDSPAS 708
Query: 868 EPPAGGLHPAPLQ----LGLGRE-----RLGAPGFAWEPFRGLELPRRAFPAAAPAPGSA 918
PP L PL+ L L E R P + P PR P +P
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Query: 919 ALLEPPERPYR---DREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHF-- 973
L PE P EPH SP+ A PHL P L L P H
Sbjct: 769 HLSPQPEEPCLCAVPEEPH-LSPQ--------AEGPHLSPQPEELH--LSPQTEEPHLSP 817
Query: 974 ----PRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGP--PTPPGPPRSRTTP 1021
P LSP + L +P + +P P + P PP PR P
Sbjct: 818 VPEEPCLSPQPEESHL---SPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868
Score = 38.9 bits (89), Expect = 0.026
Identities = 69/245 (28%), Positives = 85/245 (34%), Gaps = 63/245 (25%)
Query: 810 LGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEP 869
LG++G E + E +P EE MP P S +P E S P
Sbjct: 419 LGKAGVQLEPQLE-------APLNEE---MPLLPPPEESPLSPPPE-------ESPTSPP 461
Query: 870 P-AGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPER-P 927
P A L P P +L P L P P + P P + L PPE P
Sbjct: 462 PEASRLSPPPEEL---------PASPLPEALHLSRPLEESPLSPP-PEESPLSPPPESSP 511
Query: 928 YRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGL-- 985
+ E SP P P +PAL+ L P A LSP + L
Sbjct: 512 FSPLEESPLSP------------PEESPPSPALETPLSPPPEA---SPLSPPFEESPLSP 556
Query: 986 ----LARTPPAAAALGAPPPLVTAAGP-----PTPPGPPRSRTTPLGGLGPGEARDYSPS 1036
L +PP A+ +PPP + P P P P SR P P E SP
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP-----PFEESPLSP- 610
Query: 1037 RNPPE 1041
PPE
Sbjct: 611 --PPE 613
Score = 38.5 bits (88), Expect = 0.033
Identities = 60/225 (26%), Positives = 80/225 (35%), Gaps = 19/225 (8%)
Query: 813 SGAPAEREAEPRV-KESRSPAKEEAAKMPARASPPHSKAA---PGDVKVKEERGEDEASE 868
S P E P + K SP E+ + P + P PG+ + GE SE
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 869 PPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFP----AAAPAPGSAALLEPP 924
P L P P +L L G P + + LP P AA PA LE P
Sbjct: 903 PGEPPLSPLPEELPLSPS--GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960
Query: 925 ERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNG 984
D +P + LE +P PP A D +P + P SP +
Sbjct: 961 FGAKGDSDPESPLAAPI---LETPISP--PPEANCTDPEPVPPMILPPSPG-SPVGPASP 1014
Query: 985 LLARTPPAAAALGAPPPLVTAAGPP---TPPGPPRSRTTPLGGLG 1026
+L P + LV PP +PP P S +PL +G
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059
Score = 37.7 bits (86), Expect = 0.057
Identities = 60/226 (26%), Positives = 74/226 (32%), Gaps = 29/226 (12%)
Query: 834 EEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLH--------PAPLQLGLGR 885
E+ + +R SPP PGD E A + G H P PLQ
Sbjct: 363 EQHTPVCSRFSPPE----PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEA-- 416
Query: 886 ERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGEL 945
+ LG G EP LE P P P + L PPE P EL
Sbjct: 417 KPLGKAGVQLEP--QLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL 474
Query: 946 ERARAP---HL-------PPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAA 995
+ P HL P + P + L P + F L + L + PA
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 996 LGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPE 1041
+PPP + PP P L P EA SP PPE
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP---PPE 577
Score = 35.4 bits (80), Expect = 0.28
Identities = 74/301 (24%), Positives = 99/301 (32%), Gaps = 42/301 (13%)
Query: 726 LPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRL 785
LP P E+ L P P PP +A R+S EE L +
Sbjct: 441 LPPPEES--PLSPPPEESPTSPP----PEASRLSP----------PPEELPASPLPEALH 484
Query: 786 LSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASP 845
LSR +P P L E E P + SPA E P ASP
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 846 PHSKAAPGDVKVKEERGEDEASEPP--AGGLHPAPLQLGLGRERLGAPGFAWEPFRGLEL 903
+ P + E+ + PP A L P P E +P P
Sbjct: 545 ---LSPPFEESPLSPPPEELPTSPPPEASRLSPPP------EESPMSPPPEESPMSPPPE 595
Query: 904 PRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGA 963
R FP +P S E P P + PE + + P P +P + +
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE----DSPMSPPPEESPMSPPPEVS 651
Query: 964 LLPSLGALHFPRLSPAALHNGLLA------RTPPAAAALGAPPPLVTAAGPP---TPPGP 1014
L L + RLSP + L +PP A+ +PPP + PP +P P
Sbjct: 652 RLSPLPVVS--RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 1015 P 1015
P
Sbjct: 710 P 710
Score = 34.7 bits (78), Expect = 0.48
Identities = 90/383 (23%), Positives = 126/383 (32%), Gaps = 73/383 (19%)
Query: 682 PFSRPSTFGGL--GSLSSHA----FGGLGSHALAPG---GSIFAPKEGSSVHGLPSPHEA 732
P RP GGL G+L S + + GL G F+P+ G P
Sbjct: 1920 PLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGE-------PDSP 1972
Query: 733 WNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRAS-- 790
W PS P P D L+ + R ++++E L + A+
Sbjct: 1973 WTGSGGTTPSTPTTPTTEGEGDG-----LSYNQRSLQRWEKDEELGQLSTISPVLYANIN 2027
Query: 791 -PATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSK 849
P +P + +L R PA +A K + A K+ +A +K
Sbjct: 2028 FPNLKQDYPDWSSRCKQIMKLWRK-VPAADKAPYLQKAKDNRAAHRINKVQKQAESQINK 2086
Query: 850 AAP-GDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAF 908
GD+ K +R PP G +P +G+P GL F
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP----AGLSTSADGF 2142
Query: 909 --PAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLP 966
P A PG P+ P GEL P +P P+ D L
Sbjct: 2143 LKPPAGSVPG-------PDSP---------------GELFLKLPPQVPAQVPSQDPFGLA 2180
Query: 967 SLGALH--FPRLSPAALHNGLLARTPPAAAALGAP--PPLVTAAGPPTPPGPPRSRTTPL 1022
L FP P PP + GAP PP++ A+ P P TTP
Sbjct: 2181 PAYPLEPRFPTAPPTY---------PPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP- 2230
Query: 1023 GGLGPGEARDYSPSRNPPEVEAR 1045
PG R + PS P ++ R
Sbjct: 2231 ----PGTPR-HQPSTPDPFLKPR 2248
Score = 30.8 bits (68), Expect = 7.0
Identities = 62/250 (24%), Positives = 75/250 (30%), Gaps = 48/250 (19%)
Query: 265 ASPAPHAAPCP----GPPPGSRANPLVKKEPPAPHRHT-----PQPPPPQP-----RGLL 310
AS PH P G PGS L+ + P R PQPP P P +GL
Sbjct: 4127 ASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLP 4186
Query: 311 PTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQ 370
+ ++G Q L K+ L P L ++ Q
Sbjct: 4187 GVGIMPTVGQLRAQLQGV----------------LAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 371 AQHQLHAAMFAAPPTLPPPPALPASSLV-----LPGHPADHELLRQELNTRFLVQSAERP 425
Q Q A P P P L+ L G P QEL Q R
Sbjct: 4231 LQ-QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL 4289
Query: 426 GASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFP-------AGLPPTPPAAPPPF 478
A PGAL H + + P P A LPPT P P P
Sbjct: 4290 PAP--PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP- 4346
Query: 479 DKYAPKLDSP 488
P L+ P
Sbjct: 4347 --QGPTLEPP 4354
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/321 (25%), Positives = 113/321 (35%), Gaps = 79/321 (24%)
Query: 230 KGPALEKSEAKAGPVPKVSGLERSRELSAES-----FLPTASPAPH----AAPCPGPPPG 280
KG +++ +GP + G + + FLP+ +P H AA P PPP
Sbjct: 1573 KGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPP- 1631
Query: 281 SRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSS 340
PPAP H Q P +H S+ G A G H S+++
Sbjct: 1632 ---------PPPAPGPHLVQQPN--------SHQQHSVAHVVGPVHAVTPGSHIHSQTA- 1673
Query: 341 APLGLGKHVSLSP--------HGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL 392
G H+ P H P PH ST L++Q QH +++A PPPP
Sbjct: 1674 -----GHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAP-------PPPPPP 1721
Query: 393 PASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQH 452
P SS++ GH H Q L+ G L P + H + Q
Sbjct: 1722 PPSSVLASGH---HTTSAQALH------HPPHQGPPLFPSS-------AHPTVPPYPSQA 1765
Query: 453 THQHQHTFAPFPAGLPP-TPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTL 511
T H T P P P T P P P + P+ + + P+ P
Sbjct: 1766 T--HHTTLGPGPQHQPSGTGPHCPLP-------VTGPHLQPQGPNSIPT-----PTASGF 1811
Query: 512 LPHPGPFGSLQGAFQPKVSDP 532
PHPG G P+ + P
Sbjct: 1812 CPHPGSVALPHGVQGPQQASP 1832
Score = 44.7 bits (104), Expect = 5e-04
Identities = 105/487 (21%), Positives = 155/487 (31%), Gaps = 129/487 (26%)
Query: 118 KPRESETCPPAEPSENR-----RPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGG 172
+P + CP + S+N + + GSPG + G K+ +P Q TVS
Sbjct: 1331 EPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHG--KIFTKPDPQWDSTVSAS- 1387
Query: 173 DRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGP 232
EA + ++ +S + P SE+L + K P
Sbjct: 1388 ----------EAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQL----SQKLP 1433
Query: 233 ALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP 292
++ ++ P P + +S +P H P PP +P
Sbjct: 1434 SVP-TKLHCPPSPHLENPPKSST--------PHTPVQHGYLSPKPPSQQLGSPYRPHHSQ 1484
Query: 293 APHRHTPQPPP-----PQPRGLLPTHVPASLGAF-----AGHSQAAANGLHGLSRSSSAP 342
+P TPQ P P + L A+ G +G S A + + S +S+AP
Sbjct: 1485 SPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAP 1544
Query: 343 ----------------------------LGLGKHVSLSPHG--------------PGPHL 360
G ++ G PG H+
Sbjct: 1545 PPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHV 1604
Query: 361 STSHLALRSQ---AQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRF 417
+ H L SQ HQ AA+ PP PPPPA P H + + + +
Sbjct: 1605 TPGHF-LPSQNPTIHHQTAAAVVPPPP--PPPPA-----------PGPHLVQQPNSHQQH 1650
Query: 418 LVQSAERPGASLGPGALLRAEFHQHQ------------HTHQHTHQHT------HQHQHT 459
V P ++ PG+ + ++ H H H H T QHQH
Sbjct: 1651 SVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHV 1710
Query: 460 FAPFPAGLPPTPPA---APPPFDKYAPKLDSPYFRHSSVSFFPSFP-PAIPGLPTLLPH- 514
P PP PP+ A A L P H FPS P +P P+ H
Sbjct: 1711 VNSAPPPPPPPPPSSVLASGHHTTSAQALHHP--PHQGPPLFPSSAHPTVPPYPSQATHH 1768
Query: 515 ----PGP 517
PGP
Sbjct: 1769 TTLGPGP 1775
Score = 32.0 bits (71), Expect = 3.1
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%)
Query: 418 LVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFP-----AGLPPTPP 472
+ +E P + ++ + HQ +H H H + P+ A PPTPP
Sbjct: 19 MAAGSEPESVEASPVVVEKSNSYPHQLYTSSSH---HSHSYIGLPYADHNYGARPPPTPP 75
Query: 473 AAPPP 477
A+PPP
Sbjct: 76 ASPPP 80
Score = 30.4 bits (67), Expect = 9.1
Identities = 42/145 (28%), Positives = 52/145 (35%), Gaps = 31/145 (21%)
Query: 909 PAAAPAPGS------AALLEPPERPYRDREPHGYSPERLRGELERARAPHL-------PP 955
P A PGS A PP P PH + P L+ +A H PP
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717
Query: 956 AAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPP 1015
P ++L S S ALH+ PP PP ++A P PP P
Sbjct: 1718 PPPPPPSSVLAS----GHHTTSAQALHH------PPHQG----PPLFPSSAHPTVPPYP- 1762
Query: 1016 RSRTTPLGGLGPGEARDYSPSRNPP 1040
S+ T LGPG + PS P
Sbjct: 1763 -SQATHHTTLGPGP--QHQPSGTGP 1784
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/321 (25%), Positives = 113/321 (35%), Gaps = 79/321 (24%)
Query: 230 KGPALEKSEAKAGPVPKVSGLERSRELSAES-----FLPTASPAPH----AAPCPGPPPG 280
KG +++ +GP + G + + FLP+ +P H AA P PPP
Sbjct: 1573 KGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPP- 1631
Query: 281 SRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSS 340
PPAP H Q P +H S+ G A G H S+++
Sbjct: 1632 ---------PPPAPGPHLVQQPN--------SHQQHSVAHVVGPVHAVTPGSHIHSQTA- 1673
Query: 341 APLGLGKHVSLSP--------HGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL 392
G H+ P H P PH ST L++Q QH +++A PPPP
Sbjct: 1674 -----GHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAP-------PPPPPP 1721
Query: 393 PASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQH 452
P SS++ GH H Q L+ G L P + H + Q
Sbjct: 1722 PPSSVLASGH---HTTSAQALH------HPPHQGPPLFPSS-------AHPTVPPYPSQA 1765
Query: 453 THQHQHTFAPFPAGLPP-TPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTL 511
T H T P P P T P P P + P+ + + P+ P
Sbjct: 1766 T--HHTTLGPGPQHQPSGTGPHCPLP-------VTGPHLQPQGPNSIPT-----PTASGF 1811
Query: 512 LPHPGPFGSLQGAFQPKVSDP 532
PHPG G P+ + P
Sbjct: 1812 CPHPGSVALPHGVQGPQQASP 1832
Score = 44.7 bits (104), Expect = 5e-04
Identities = 105/487 (21%), Positives = 155/487 (31%), Gaps = 129/487 (26%)
Query: 118 KPRESETCPPAEPSENR-----RPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGG 172
+P + CP + S+N + + GSPG + G K+ +P Q TVS
Sbjct: 1331 EPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHG--KIFTKPDPQWDSTVSAS- 1387
Query: 173 DRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGP 232
EA + ++ +S + P SE+L + K P
Sbjct: 1388 ----------EAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQL----SQKLP 1433
Query: 233 ALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP 292
++ ++ P P + +S +P H P PP +P
Sbjct: 1434 SVP-TKLHCPPSPHLENPPKSST--------PHTPVQHGYLSPKPPSQQLGSPYRPHHSQ 1484
Query: 293 APHRHTPQPPP-----PQPRGLLPTHVPASLGAF-----AGHSQAAANGLHGLSRSSSAP 342
+P TPQ P P + L A+ G +G S A + + S +S+AP
Sbjct: 1485 SPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAP 1544
Query: 343 ----------------------------LGLGKHVSLSPHG--------------PGPHL 360
G ++ G PG H+
Sbjct: 1545 PPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHV 1604
Query: 361 STSHLALRSQ---AQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRF 417
+ H L SQ HQ AA+ PP PPPPA P H + + + +
Sbjct: 1605 TPGHF-LPSQNPTIHHQTAAAVVPPPP--PPPPA-----------PGPHLVQQPNSHQQH 1650
Query: 418 LVQSAERPGASLGPGALLRAEFHQHQ------------HTHQHTHQHT------HQHQHT 459
V P ++ PG+ + ++ H H H H T QHQH
Sbjct: 1651 SVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHV 1710
Query: 460 FAPFPAGLPPTPPA---APPPFDKYAPKLDSPYFRHSSVSFFPSFP-PAIPGLPTLLPH- 514
P PP PP+ A A L P H FPS P +P P+ H
Sbjct: 1711 VNSAPPPPPPPPPSSVLASGHHTTSAQALHHP--PHQGPPLFPSSAHPTVPPYPSQATHH 1768
Query: 515 ----PGP 517
PGP
Sbjct: 1769 TTLGPGP 1775
Score = 32.0 bits (71), Expect = 3.1
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 8/65 (12%)
Query: 418 LVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFP-----AGLPPTPP 472
+ +E P + ++ + HQ +H H H + P+ A PPTPP
Sbjct: 19 MAAGSEPESVEASPVVVEKSNSYPHQLYTSSSH---HSHSYIGLPYADHNYGARPPPTPP 75
Query: 473 AAPPP 477
A+PPP
Sbjct: 76 ASPPP 80
Score = 30.4 bits (67), Expect = 9.1
Identities = 42/145 (28%), Positives = 52/145 (35%), Gaps = 31/145 (21%)
Query: 909 PAAAPAPGS------AALLEPPERPYRDREPHGYSPERLRGELERARAPHL-------PP 955
P A PGS A PP P PH + P L+ +A H PP
Sbjct: 1658 PVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPP 1717
Query: 956 AAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPP 1015
P ++L S S ALH+ PP PP ++A P PP P
Sbjct: 1718 PPPPPPSSVLAS----GHHTTSAQALHH------PPHQG----PPLFPSSAHPTVPPYP- 1762
Query: 1016 RSRTTPLGGLGPGEARDYSPSRNPP 1040
S+ T LGPG + PS P
Sbjct: 1763 -SQATHHTTLGPGP--QHQPSGTGP 1784
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 58.5 bits (140), Expect = 3e-08
Identities = 112/428 (26%), Positives = 148/428 (34%), Gaps = 68/428 (15%)
Query: 622 GAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTD 681
GA+ L G P P F + Q R P P GP A + +P P +
Sbjct: 146 GARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQV-PDLAPGGPGA---AGVPGAPPEE 201
Query: 682 PFS-RPSTFGGLGSLSSHAFG---------GLGSHALAPGGS-IFAPKEGSSVHGLPSPH 730
P + RP+ G G S G G + PG S + A +GSS +
Sbjct: 202 PQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAAS 261
Query: 731 EAWNRLHRAPPSFPAPPPW-PKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRA 789
A R P+ APP W P ++ + A+ R P N + +
Sbjct: 262 SAV----RLTPAANAPPLWVPGAIGSPSQEAV----RPPSNFTGSSPWMEISGPPFEIGS 313
Query: 790 SPATPAGHPV---SGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARA--- 843
+PA PV S + + SGAP +RE + R P +EEAA+M A
Sbjct: 314 APAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRE-----RAERPPVEEEAAEMEGAADAA 368
Query: 844 ------SPPHSKAAPGDVKVKEE-RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWE 896
SP + A G R A P G P G + FA +
Sbjct: 369 EGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAAD 428
Query: 897 PFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPH-------GYSPERLRGELE-RA 948
P G A PAA P S A + P P P G +PE
Sbjct: 429 PDSG------AAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAET 482
Query: 949 RAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAA-----LGAPPPLV 1003
RA H+ PAAP P+ A ++ AA PA+ A L P P +
Sbjct: 483 RAAHVAPAAPDAGAPTAPAASATRAAQVRRAA-------SAAPASGARRKIHLRPPSPEI 535
Query: 1004 TAAGPPTP 1011
AA PPTP
Sbjct: 536 QAADPPTP 543
Score = 36.2 bits (82), Expect = 0.17
Identities = 45/178 (25%), Positives = 58/178 (32%), Gaps = 22/178 (12%)
Query: 140 GSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAV 199
GSP A AR P P+ G D DS T+ DP DS A A
Sbjct: 379 GSPAAGAASADTAARAAPAAPADP------DSGATPEDPDS---GTAPADP--DSGAFAA 427
Query: 200 -----SGRGYSCDSESGPDDKASVGSEKLFAPGTDKGP-ALEKSEAKAGPVPKVSGLERS 253
+ D +SG A + AP P A EA A P +
Sbjct: 428 DPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHV 487
Query: 254 RELSAESFLPTA-----SPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQP 306
+ ++ PTA + A P S A + PP+P PP P+P
Sbjct: 488 APAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRP 545
Score = 32.7 bits (73), Expect = 1.8
Identities = 60/251 (23%), Positives = 81/251 (32%), Gaps = 59/251 (23%)
Query: 704 GSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTN 763
G+ A GG + +P GS G S A RA P+ PA
Sbjct: 363 GAADAAEGGKVPSPGYGSPAAGAASADTA----ARAAPAAPA------------------ 400
Query: 764 HDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEP 823
+PD+G ++ D S +PA P SG APA+ ++
Sbjct: 401 ---DPDSGATPEDPD--------SGTAPADPD----SGAFAADPDSGAAPAAPADPDSGA 445
Query: 824 RVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGL 883
P A PA + AP E R A P G AP
Sbjct: 446 APDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAP----- 500
Query: 884 GRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAAL--LEPPERPYRDREPHGYSPERL 941
A R ++ R A +AAPA G+ L PP + +P P R
Sbjct: 501 ----------AASATRAAQVRRAA--SAAPASGARRKIHLRPPSPEIQAADPPTPRPTRA 548
Query: 942 ---RGELERAR 949
RG+ E +R
Sbjct: 549 SAWRGKSESSR 559
Score = 31.6 bits (70), Expect = 4.1
Identities = 41/134 (30%), Positives = 50/134 (37%), Gaps = 21/134 (15%)
Query: 901 LELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYS---PERLRGELE---------RA 948
LE P A P A P+P EPP E G + PE R + A
Sbjct: 31 LEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA 90
Query: 949 RAPHLPPAAPALD-GALLPSLGALHFPRLS----PAALHNGLLARTP---PAAAALGAPP 1000
+ PP A+ A PSLG +P L P+ +H GL A P A GA P
Sbjct: 91 HGSYSPPPEEAMPFEAEQPSLGGF-WPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARP 149
Query: 1001 PLVTAAGPPTPPGP 1014
L + PP P
Sbjct: 150 GLGGYSPPPEEAMP 163
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 57.4 bits (137), Expect = 7e-08
Identities = 104/455 (22%), Positives = 162/455 (35%), Gaps = 81/455 (17%)
Query: 7 PSRRSRAQRDRGR---RREAARDARAQSPSSGDEP--------EPSPGKENAGLRGAPPR 55
PS + A +D G+ + A A P P EP+P E G PP
Sbjct: 735 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP- 793
Query: 56 GAAPAPRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKE-KWERR 114
AP +A PP + E +EEE + +E+ KP +E +
Sbjct: 794 --APPSPSAPPPVVPKEE---KEEET---------AAAPPVEEGEEQKPPAAEELAVDTG 839
Query: 115 LIKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDR 174
++P +SE AE + G + E +GA K + + T +K
Sbjct: 840 KAEEPVKSECTEEAEEGPAK-----GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGA 894
Query: 175 DSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTD----- 229
D DS AT S D + ++E G ++ L P D
Sbjct: 895 PQDSDS--SATCSADEVD--------------EAEGGDKNRLLSPRPSLLTPTGDPRANA 938
Query: 230 ---KGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPL 286
K L++ + +A +P + + + E E PT PAP P P PP +
Sbjct: 939 SPQKPLDLKQLKQRAAAIPPIQ-VTKVHEPPREDAAPT-KPAP---PAPPPPQNLQPESD 993
Query: 287 VKKEP-PAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGL 345
++P +P + P PP + P AFA +Q + P+
Sbjct: 994 APQQPGSSPRGKSRSPAPPADK---EAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPP 1050
Query: 346 GKHVSLSPHGPGP----HLSTSH-LALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLP 400
+ + SPH P P + H L L H + PPT+ PP L +S+
Sbjct: 1051 REVIKASPHAPDPSAFSYAPPGHPLPL---GLHDTARPVLPRPPTISNPPPLISSA---- 1103
Query: 401 GHPADHE----LLRQELNTRFLVQSAERPGASLGP 431
HP+ E + Q ++ + V +E A +GP
Sbjct: 1104 KHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGP 1138
Score = 44.3 bits (103), Expect = 6e-04
Identities = 87/332 (26%), Positives = 109/332 (32%), Gaps = 57/332 (17%)
Query: 717 PKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPP-WPKSVDAERVSALTNHDREPDNGKEEQ 775
P S G P+P A PPS APPP PK E +A P EEQ
Sbjct: 779 PTPASEATGAPTPPPA-------PPSPSAPPPVVPKEEKEEETAA-----APPVEEGEEQ 826
Query: 776 ERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEE 835
+ E+ A A PV E G AE AE + + K+E
Sbjct: 827 KPPAAEEL-----AVDTGKAEEPVKSECTEEAEEGPAKGKDAE-AAEATAEGALKAEKKE 880
Query: 836 AAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGG----LHPAPLQLGLGRERLGAP 891
RA+ S AP D DE E G L P P L G P
Sbjct: 881 GGS--GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLL----TPTGDP 934
Query: 892 GFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPER----PYRDREPHGYSPERLRGELER 947
P + L+L + AAA P + P R P + P P+ L+ E +
Sbjct: 935 RANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDA 994
Query: 948 ARAP-------HLPPAAPALDGALLPSLGALHFPRLS---------PAALHNGLLARTPP 991
+ P PA PA A P + FP + P +GL PP
Sbjct: 995 PQQPGSSPRGKSRSPAPPADKEAEKP----VFFPAFAAEAQKLPGDPPCWTSGLPFPVPP 1050
Query: 992 AAAALGAPPPLVTAAGPPTPPGPPRSRTTPLG 1023
+P +A PPG P PLG
Sbjct: 1051 REVIKASPHAPDPSAFSYAPPGHP----LPLG 1078
Score = 41.2 bits (95), Expect = 0.005
Identities = 71/304 (23%), Positives = 98/304 (32%), Gaps = 51/304 (16%)
Query: 726 LPSPHEAWNRLHRAPPSFPAPPPW-PKSVDAERVSALTNHDREPDNGKEEQERDLLEKTR 784
LP+ + ++ H + P P P K + DRE D +E +E+ +L T
Sbjct: 1752 LPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDRE-REKSILTSTT 1810
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAK-MPARA 843
+ A P SG + G G + R A SP + R
Sbjct: 1811 TVEHAPIWRPGTEQSSG----SSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRP 1866
Query: 844 SPPHSKAAPGDVKVKEE------RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEP 897
S H+ G + E R +S P LG G EP
Sbjct: 1867 SVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEP 1926
Query: 898 FRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAA 957
+ LP+ A A P ERP D H + + PPA
Sbjct: 1927 ---VLLPKEAPRVARP-----------ERPRADTG-HAFLAK--------------PPAR 1957
Query: 958 PALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRS 1017
L+ A PS G+ P + P + H +ARTP L P PP PP S
Sbjct: 1958 SGLEPASSPSKGSEPRPLVPPVSGH-ATIARTPAKN--------LAPHHASPDPPAPPAS 2008
Query: 1018 RTTP 1021
+ P
Sbjct: 2009 ASDP 2012
Score = 41.2 bits (95), Expect = 0.005
Identities = 72/282 (25%), Positives = 91/282 (32%), Gaps = 82/282 (29%)
Query: 245 PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP------------ 292
P+V+ ER R + +FL P P GS PLV PP
Sbjct: 1934 PRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV---PPVSGHATIARTPA 1990
Query: 293 ---APHRHTPQPPPPQPRGLLPTHVPASLGAFA-GHSQAAANGLHGLSRS---------- 338
APH +P PP P P F+ + + G HG S S
Sbjct: 1991 KNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPV 2050
Query: 339 SSAPL----GLGKHV----------SLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP 384
SS L GL KH+ L P PGP + L +A H P
Sbjct: 2051 SSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGP------VKLGGEAAH--------LPH 2096
Query: 385 TLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQH 444
P P + P+SS L+Q+A PG + A+
Sbjct: 2097 LRPLPESQPSSSP--------------------LLQTA--PGVKGHQRVVTLAQHISEVI 2134
Query: 445 THQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLD 486
T +T H Q AP PA L P A+ P D P D
Sbjct: 2135 TQDYTRHHP---QQLSAPLPAPLYSFPGASCPVLDLRRPPSD 2173
Score = 38.5 bits (88), Expect = 0.033
Identities = 56/242 (23%), Positives = 86/242 (35%), Gaps = 46/242 (19%)
Query: 773 EEQERDLLEKTRLLS-RASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSP 831
E E + +K RLLS R S TP G P + + +L + A +V + P
Sbjct: 908 EVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEP 967
Query: 832 AKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAP 891
+E+AA P + +PP + P +++ + + + S P PAP + + P
Sbjct: 968 PREDAA--PTKPAPP-APPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFP 1024
Query: 892 GFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAP 951
FA E + P P S P R PH P
Sbjct: 1025 AFAAEA--------QKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFS--------- 1067
Query: 952 HLPPAAPALDGALLPSLGALHFPRLSPAALHNG---LLARTPPAAAALGAPPPLVTAAGP 1008
+ PP P P LH+ +L R P + PPPL+++A
Sbjct: 1068 YAPPGHPL------------------PLGLHDTARPVLPRPP----TISNPPPLISSAKH 1105
Query: 1009 PT 1010
P+
Sbjct: 1106 PS 1107
Score = 34.7 bits (78), Expect = 0.48
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 6/137 (4%)
Query: 738 RAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGH 797
+AP + +P V+ E + A E + EE E + + S SP T A
Sbjct: 685 KAPAAASEEAAFPPVVEDEEMEASGVSGNEEEM-VEEAEATVNNSSDTESIPSPHTEAAK 743
Query: 798 PVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAK----EEAAKMPARASPPHSKAAPG 853
+ + LG G P P ++ +P + EA P P S +AP
Sbjct: 744 DTGQNGPKPPATLGADGPPPGPPTPPP-EDIPAPTEPTPASEATGAPTPPPAPPSPSAPP 802
Query: 854 DVKVKEERGEDEASEPP 870
V KEE+ E+ A+ PP
Sbjct: 803 PVVPKEEKEEETAAAPP 819
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/70 (35%), Positives = 26/70 (37%), Gaps = 11/70 (15%)
Query: 979 AALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPG---PPRSRTTPLG---GLGPGEARD 1032
AA G PPA PPP GPPTPP P + TP G
Sbjct: 741 AAKDTGQNGPKPPATLGADGPPP-----GPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 795
Query: 1033 YSPSRNPPEV 1042
SPS PP V
Sbjct: 796 PSPSAPPPVV 805
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 7/82 (8%)
Query: 6 RPSRRSRAQRDRGRRREAARDAR-----AQSPSSGDEPEP--SPGKENAGLRGAPPRGAA 58
R +R R + D G A AR A SPS G EP P P +A + P + A
Sbjct: 1935 RVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLA 1994
Query: 59 PAPRTARPPRRRRRESSSQEEE 80
P + PP S E+
Sbjct: 1995 PHHASPDPPAPPASASDPHREK 2016
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 57.0 bits (136), Expect = 9e-08
Identities = 104/455 (22%), Positives = 162/455 (35%), Gaps = 82/455 (18%)
Query: 7 PSRRSRAQRDRGR---RREAARDARAQSPSSGDEP--------EPSPGKENAGLRGAPPR 55
PS + A +D G+ + A A P P EP+P E G PP
Sbjct: 752 PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP- 810
Query: 56 GAAPAPRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKE-KWERR 114
AP +A PP + E +EEE + +E+ KP +E +
Sbjct: 811 --APPSPSAPPPVVPKEE---KEEET---------AAAPPVEEGEEQKPPAAEELAVDTG 856
Query: 115 LIKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDR 174
++P +SE AE + G + E +GA K + + T +K
Sbjct: 857 KAEEPVKSECTEEAEEGPAK-----GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGA 911
Query: 175 DSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTD----- 229
D DS AT S D + ++E G ++ L P D
Sbjct: 912 PQDSDS--SATCSADEVD--------------EAEGGDKNRLLSPRPSLLTPTGDPRANA 955
Query: 230 ---KGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPL 286
K L++ + +A +P + + + E E PT PAP P P PP +
Sbjct: 956 SPQKPLDLKQLKQRAAAIPPI--VTKVHEPPREDAAPT-KPAP---PAPPPPQNLQPESD 1009
Query: 287 VKKEP-PAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGL 345
++P +P + P PP + P AFA +Q + P+
Sbjct: 1010 APQQPGSSPRGKSRSPAPPADK---EAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPP 1066
Query: 346 GKHVSLSPHGPGP----HLSTSH-LALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLP 400
+ + SPH P P + H L L H + PPT+ PP L +S+
Sbjct: 1067 REVIKASPHAPDPSAFSYAPPGHPLPL---GLHDTARPVLPRPPTISNPPPLISSA---- 1119
Query: 401 GHPADHE----LLRQELNTRFLVQSAERPGASLGP 431
HP+ E + Q ++ + V +E A +GP
Sbjct: 1120 KHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGP 1154
Score = 45.8 bits (107), Expect = 2e-04
Identities = 90/334 (26%), Positives = 111/334 (33%), Gaps = 62/334 (18%)
Query: 717 PKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPW-PKSVDAERVSALTNHDREPDNGKEEQ 775
P S G P+P A PPS APPP PK E +A P EEQ
Sbjct: 796 PTPASEATGAPTPPPA-------PPSPSAPPPVVPKEEKEEETAAAP-----PVEEGEEQ 843
Query: 776 ERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEE 835
+ E+ A A PV E G AE AE + + K+E
Sbjct: 844 KPPAAEEL-----AVDTGKAEEPVKSECTEEAEEGPAKGKDAEA-AEATAEGALKAEKKE 897
Query: 836 AAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGG----LHPAPLQLGLGRERLGAP 891
RA+ S AP D DE E G L P P L G P
Sbjct: 898 GGS--GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLL----TPTGDP 951
Query: 892 GFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPER---PYRDREPHGYSPERLRGELERA 948
P + L+L + AAA P + EPP P + P P+ L+ E +
Sbjct: 952 RANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESD-- 1009
Query: 949 RAPHLP----------PAAPALDGALLPSLGALHFPRLS---------PAALHNGLLART 989
AP P PA PA A P + FP + P +GL
Sbjct: 1010 -APQQPGSSPRGKSRSPAPPADKEAEKP----VFFPAFAAEAQKLPGDPPCWTSGLPFPV 1064
Query: 990 PPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLG 1023
PP +P +A PPG P PLG
Sbjct: 1065 PPREVIKASPHAPDPSAFSYAPPGHP----LPLG 1094
Score = 41.2 bits (95), Expect = 0.005
Identities = 71/304 (23%), Positives = 98/304 (32%), Gaps = 51/304 (16%)
Query: 726 LPSPHEAWNRLHRAPPSFPAPPPW-PKSVDAERVSALTNHDREPDNGKEEQERDLLEKTR 784
LP+ + ++ H + P P P K + DRE D +E +E+ +L T
Sbjct: 1768 LPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDRE-REKSILTSTT 1826
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAK-MPARA 843
+ A P SG + G G + R A SP + R
Sbjct: 1827 TVEHAPIWRPGTEQSSG----SSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRP 1882
Query: 844 SPPHSKAAPGDVKVKEE------RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEP 897
S H+ G + E R +S P LG G EP
Sbjct: 1883 SVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEP 1942
Query: 898 FRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAA 957
+ LP+ A A P ERP D H + + PPA
Sbjct: 1943 ---VLLPKEAPRVARP-----------ERPRADTG-HAFLAK--------------PPAR 1973
Query: 958 PALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRS 1017
L+ A PS G+ P + P + H +ARTP L P PP PP S
Sbjct: 1974 SGLEPASSPSKGSEPRPLVPPVSGH-ATIARTPAKN--------LAPHHASPDPPAPPAS 2024
Query: 1018 RTTP 1021
+ P
Sbjct: 2025 ASDP 2028
Score = 41.2 bits (95), Expect = 0.005
Identities = 72/282 (25%), Positives = 91/282 (32%), Gaps = 82/282 (29%)
Query: 245 PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP------------ 292
P+V+ ER R + +FL P P GS PLV PP
Sbjct: 1950 PRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV---PPVSGHATIARTPA 2006
Query: 293 ---APHRHTPQPPPPQPRGLLPTHVPASLGAFA-GHSQAAANGLHGLSRS---------- 338
APH +P PP P P F+ + + G HG S S
Sbjct: 2007 KNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPV 2066
Query: 339 SSAPL----GLGKHV----------SLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP 384
SS L GL KH+ L P PGP + L +A H P
Sbjct: 2067 SSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGP------VKLGGEAAH--------LPH 2112
Query: 385 TLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQH 444
P P + P+SS L+Q+A PG + A+
Sbjct: 2113 LRPLPESQPSSSP--------------------LLQTA--PGVKGHQRVVTLAQHISEVI 2150
Query: 445 THQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLD 486
T +T H Q AP PA L P A+ P D P D
Sbjct: 2151 TQDYTRHHP---QQLSAPLPAPLYSFPGASCPVLDLRRPPSD 2189
Score = 32.0 bits (71), Expect = 3.1
Identities = 62/310 (20%), Positives = 108/310 (34%), Gaps = 56/310 (18%)
Query: 2 EAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLR-GAPPRGAAPA 60
E + S+ + +GRR+ + A +S + P E A + R
Sbjct: 560 EKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEE 619
Query: 61 PRTARPPRRRRRESSSQEEEVIDGFAIAS-----FSTLEALEKDMALKPHERKEKWERRL 115
TA+ + S ++ ++ F+ + D L+ H+ K + ER
Sbjct: 620 METAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNA 679
Query: 116 IKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRD 175
+K +++ PA SE EA P P+ ++M+ + G + +
Sbjct: 680 RRKKKKA----PAAASE-----EAAFP--------------PVVEDEEMEASGVSGNEEE 716
Query: 176 SDDDS-VLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPAL 234
+++ L A+ + P + S A S D+ES P +P T+
Sbjct: 717 MVEEAEALHASGNEVPRGECSGPATVNN--SSDTESIP------------SPHTEAA--- 759
Query: 235 EKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAP 294
K + GP P + L A+ P P P P P + A+ P P
Sbjct: 760 -KDTGQNGPKPPAT-------LGADG-PPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP 810
Query: 295 HRHTPQPPPP 304
+P PPP
Sbjct: 811 APPSPSAPPP 820
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/70 (35%), Positives = 26/70 (37%), Gaps = 11/70 (15%)
Query: 979 AALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPG---PPRSRTTPLG---GLGPGEARD 1032
AA G PPA PPP GPPTPP P + TP G
Sbjct: 758 AAKDTGQNGPKPPATLGADGPPP-----GPPTPPPEDIPAPTEPTPASEATGAPTPPPAP 812
Query: 1033 YSPSRNPPEV 1042
SPS PP V
Sbjct: 813 PSPSAPPPVV 822
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 7/82 (8%)
Query: 6 RPSRRSRAQRDRGRRREAARDAR-----AQSPSSGDEPEP--SPGKENAGLRGAPPRGAA 58
R +R R + D G A AR A SPS G EP P P +A + P + A
Sbjct: 1951 RVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLA 2010
Query: 59 PAPRTARPPRRRRRESSSQEEE 80
P + PP S E+
Sbjct: 2011 PHHASPDPPAPPASASDPHREK 2032
Score = 30.4 bits (67), Expect = 9.1
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 790 SPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAK----EEAAKMPARASP 845
SP T A + + LG G P P ++ +P + EA P
Sbjct: 753 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPP-EDIPAPTEPTPASEATGAPTPPPA 811
Query: 846 PHSKAAPGDVKVKEERGEDEASEPP 870
P S +AP V KEE+ E+ A+ PP
Sbjct: 812 PPSPSAPPPVVPKEEKEEETAAAPP 836
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 57.0 bits (136), Expect = 9e-08
Identities = 96/407 (23%), Positives = 152/407 (37%), Gaps = 83/407 (20%)
Query: 6 RPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTAR 65
R R QR+R R RE R+ + E E KE
Sbjct: 406 RERERENRQRERERERERDRERERRQREREREREHERDKE-------------------- 445
Query: 66 PPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIK-KPRESET 124
R+RR+E +E D EKD + +R+++ E+ K KPR +
Sbjct: 446 --RQRRKEEWERERAKRD-------------EKDRQHRDRDREKEREKEKGKPKPRSPQ- 489
Query: 125 CPPAEPSENRRPLEAGSPGQDLEPACDGAR--KVPLQPSKQMKVTVSKGGDRDSDDDSVL 182
PP+ +E + EA + G ++ A + + P K++ V+VS R S
Sbjct: 490 -PPSRQAEPPKK-EAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSAS 547
Query: 183 EATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAG 242
A++S S S + + SG G S ++ S ++ + + + S +
Sbjct: 548 SASASNSSRSSSRSSSYSGSGSS-------RSRSRSSSYSSYSSRSSRHSSFSGSRS--- 597
Query: 243 PVPKVSGLERSRELSAESFLPTASPAPHAAPC-----PGPPPGSRANPLVKK--EPPAPH 295
RSR S+ S P+ +P+PH P PPPG VKK PPAP
Sbjct: 598 ---------RSRSFSS-SPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPP 647
Query: 296 RHT----PQPPPPQP-------RGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLG 344
+ T P P P +P R P P +G + + G S S S L
Sbjct: 648 QATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSG-SSSRSRSLS 706
Query: 345 LGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPA 391
+ S+S S+S ++ S+ + A+ ++ + P PA
Sbjct: 707 VS---SVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPA 750
Score = 48.9 bits (115), Expect = 2e-05
Identities = 89/390 (22%), Positives = 137/390 (35%), Gaps = 76/390 (19%)
Query: 626 DLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSR 685
D + R +P G AR ++ ++ ASN S+ S+ +G SR
Sbjct: 517 DPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSR-SR 575
Query: 686 PSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRL--HRAPP-- 741
S++ S SS GS + + S S PSPH R APP
Sbjct: 576 SSSYSSYSSRSSRHSSFSGSRSRSRSFS-----SSPSPSPTPSPHRPSIRTKGEPAPPPG 630
Query: 742 -------SFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKT----------- 783
PAPPP P A + +A +P + +E + ++ +T
Sbjct: 631 KAGEKSVKKPAPPPAPPQ--ATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSG 688
Query: 784 ----------------------RLLSRASPATPAGHPVSG------LLLRAQSELGRSGA 815
+S A+ ++ + H V L S RS A
Sbjct: 689 SGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPA 748
Query: 816 PAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEP--PAGG 873
PA+ E + KEE K + PP S P K ++ + + P P G
Sbjct: 749 PAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808
Query: 874 LHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREP 933
A ++ L A + + + + R++ P A P ++ P+R RDR+
Sbjct: 809 TFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQS-PPPAKRPNTS-----PDRGSRDRKS 862
Query: 934 HGY----SPERLRGELERARAPHLPPAAPA 959
G PER RG+ +A PAAPA
Sbjct: 863 GGRLGSPKPERQRGQNSKA------PAAPA 886
Score = 34.7 bits (78), Expect = 0.48
Identities = 74/341 (21%), Positives = 114/341 (33%), Gaps = 64/341 (18%)
Query: 7 PSRRSRAQR---------DRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGA 57
P RRS++ + R RRR + A + +S S +G + R +
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
Query: 58 APAPRTARPPR---------RRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERK 108
+ + ++R R R R SSS S T + + A P +
Sbjct: 578 SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRT----KGEPAPPPGKAG 633
Query: 109 EKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTV 168
EK +KKP PPA P + P + +P ++ P + + +
Sbjct: 634 EK----SVKKPAP----PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLS 685
Query: 169 SKG---GDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFA 225
G G S S + S S SSA + S +S DSE D AS S
Sbjct: 686 GSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSS---- 741
Query: 226 PGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANP 285
+ + PA ++ + G K G++ + S P S
Sbjct: 742 -ASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSA------------------ 782
Query: 286 LVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQ 326
+PPA + + QP PQ P P G F H +
Sbjct: 783 ----KPPAGGKSSQQPSTPQQ---APPGQPQQ-GTFVAHKE 815
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 56.2 bits (134), Expect = 2e-07
Identities = 150/617 (24%), Positives = 216/617 (35%), Gaps = 110/617 (17%)
Query: 466 GLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGP---FGSLQ 522
G+PP P APPP +PY+ F S PP P P P P + +++
Sbjct: 828 GIPPPPQTAPPP-------PPAPYY-------FDSGPP-----PAFSPPPPPGRAYDTVR 868
Query: 523 GAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWV--GVAPAPLS 580
+F+P + R + +E L P R + AR LQ + G AP P
Sbjct: 869 SSFKPGLEA--RLGAGAAGLYEPGAALGPLPYPERQKRARSMIILQDSAPESGDAPRPPP 926
Query: 581 ASILSQKP----------------GRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAK 624
A+ ++P G + A + R +K++Q++ + A
Sbjct: 927 AATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVED--AQERAA 984
Query: 625 LDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPG-SFLPTGPLTD-- 681
L + P G FA R P+ P +G PG +F GP D
Sbjct: 985 LAVGSPGPGGGSFA---------REPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRR 1035
Query: 682 --PFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSI------FAPKEGSSVHGLPSPHEAW 733
R + F +G++ A G +L P SI P G + LPSP A
Sbjct: 1036 LEERRRSTVFLSVGAIEGSA-PGADLPSLQPSRSIDERLLGTGPTAGRDLL-LPSPVSAL 1093
Query: 734 NRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN----GKEEQERDLLEKTRLLSRA 789
L P P+ + + LT +P + +ER L + S
Sbjct: 1094 KPLVSGPSLGPSGSTF--------IHPLTGKPLDPSSPLALALAARERALASQAPSRSPT 1145
Query: 790 SPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKE-SRSPAKEEAAKMPARASPPHS 848
+P L + Q+ G+ A PR PA+ EA K+P
Sbjct: 1146 PVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVPRE-----E 1200
Query: 849 KAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAF 908
+ +P D K D + + PAG + G RLG G E R
Sbjct: 1201 RKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG----------GAEEERPGT 1250
Query: 909 PAAAPAP-GSAALLEPPERPYRDREPHGYSPERLRG------ELERARAPHLPPAA-PAL 960
P APAP SAA+ EP P R + P G + G E E A +LPPA +
Sbjct: 1251 PELAPAPMQSAAVAEPLPSP-RAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLSSS 1309
Query: 961 DGALLPSLGALHFPRLSPAALHNGLLARTP---PAAAALGAPPPLVTAAGPPTPPGPPRS 1017
D L + P NG+L TP P + P P A+G P+ PP
Sbjct: 1310 DEETREELARIGLVP-PPEEFANGVLLATPLAGPGPSPTTVPSP---ASGKPSSEPPPAP 1365
Query: 1018 RTTPLGGLGPGEARDYS 1034
+ G+ + R S
Sbjct: 1366 ESAADSGVEEADTRSSS 1382
Score = 39.3 bits (90), Expect = 0.020
Identities = 68/283 (24%), Positives = 100/283 (35%), Gaps = 44/283 (15%)
Query: 788 RASPATPAGHPVSGLLLRAQS---ELGRSGAPAERE-----------AEPRVKESRSPAK 833
R +P P P + L LR++S EL + R+ AEP ++ + A
Sbjct: 691 RRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEMLAAAAEPTLRPDIADAD 750
Query: 834 EEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPA-PLQLGLGRE------ 886
AA + R P + P ++ ER E G L P +G +
Sbjct: 751 SRAATVKQR--PTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRTKSVGEDEKLASL 808
Query: 887 ---RLGAPGFAWEPFR---GLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPER 940
R +P R G+ P + P PAP PP + P G + +
Sbjct: 809 LEGRFPRSTSMQDPVREGRGIPPPPQTAPPPPPAPYYFDSGPPPA--FSPPPPPGRAYDT 866
Query: 941 LRGELERARAPHLPPAAPAL--DGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGA 998
+R + L A L GA +LG L +P A +L + P +
Sbjct: 867 VRSSFKPGLEARLGAGAAGLYEPGA---ALGPLPYPERQKRARSMIILQDSAPESGDAPR 923
Query: 999 PPPLVT----AAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSR 1037
PPP T P PPGP +P LG A ++PS+
Sbjct: 924 PPPAATPPERPKRRPRPPGP----DSPYANLGAFSASLFAPSK 962
Score = 35.4 bits (80), Expect = 0.28
Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 938 PERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALG 997
PE+L G L + +P + L SL FPR + + P G
Sbjct: 782 PEKLPGSLRKG----IPRTKSVGEDEKLASLLEGRFPRST---------SMQDPVREGRG 828
Query: 998 APPPLVTAAGPPTPP-----GPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR 1045
PPP TA PP P GPP + + P PG A D S P +EAR
Sbjct: 829 IPPPPQTAPPPPPAPYYFDSGPPPAFSPP---PPPGRAYDTVRSSFKPGLEAR 878
Score = 35.0 bits (79), Expect = 0.37
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 201 GRGYSCDSES---GPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELS 257
GR Y S G + + G+ L+ PG GP P P+ R+
Sbjct: 861 GRAYDTVRSSFKPGLEARLGAGAAGLYEPGAALGPL---------PYPE-------RQKR 904
Query: 258 AESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPAS 317
A S + AP + P PPP + PP + P+PP P A+
Sbjct: 905 ARSMIILQDSAPESGDAPRPPPAA--------TPPERPKRRPRPPGPD-------SPYAN 949
Query: 318 LGAFA 322
LGAF+
Sbjct: 950 LGAFS 954
Score = 31.6 bits (70), Expect = 4.1
Identities = 75/331 (22%), Positives = 105/331 (31%), Gaps = 71/331 (21%)
Query: 16 DRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRRRESS 75
+R +R + + +P SGD P P P PP RP RR R
Sbjct: 900 ERQKRARSMIILQDSAPESGDAPRPPPA-------ATPPE---------RPKRRPRPPGP 943
Query: 76 SQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRR 135
+ F+ + F+ KP RK ++L E ++ R
Sbjct: 944 DSPYANLGAFSASLFA---------PSKPQRRKSPLVKQL-----------QVEDAQERA 983
Query: 136 PLEAGSPG-------QDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSR 188
L GSPG ++ P G R L ++ GG + D + E S
Sbjct: 984 ALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRST 1043
Query: 189 DPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKG-------PALEKSEAKA 241
L S A+ G D S ++ E+L G G P +
Sbjct: 1044 VFL---SVGAIEGSAPGADLPSLQPSRSI--DERLLGTGPTAGRDLLLPSPVSALKPLVS 1098
Query: 242 GPVPKVSGLERSRELSAESFLPT--------------ASPAPHAAPCP-GPPPGSRANPL 286
GP SG L+ + P+ AS AP +P P P R PL
Sbjct: 1099 GPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDADRPGPL 1158
Query: 287 -VKKEPPAPHRHTPQPPPPQPRGLLPTHVPA 316
V + P R + P PR VPA
Sbjct: 1159 FVDVQARDPERGSLASPAFSPRSPAWIPVPA 1189
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 56.2 bits (134), Expect = 2e-07
Identities = 66/269 (24%), Positives = 105/269 (39%), Gaps = 31/269 (11%)
Query: 2 EAKVRPSRR-SRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPA 60
EA RP +R + AQR R +R EA P S P K AG G P +P
Sbjct: 26 EAPRRPKQRPAPAQRLRKKRTEA--------PESPCPTGSKPRKPGAGRTGRPREEPSPD 77
Query: 61 PRTARPPR----RRRRESSSQEEEVIDGFAIA----SFSTLEALEKDMALKPHERKEKWE 112
P AR P+ R R+ +++ + + F +A + E E+D + E +EK E
Sbjct: 78 PAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKE 137
Query: 113 RRLIKKPRESETCPPAEPSENRRPLEA-----GSPGQDLEPACDGARKVPLQPSKQMKVT 167
+ L+ + A+ E R + GSP +P ++ P +M+ T
Sbjct: 138 KILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKT 197
Query: 168 VSKGGDRDSDDDSVLEATSSRDPLS---------DSSAHAVSGRGYSCDSESGPDDKASV 218
KG D S A++ + P + D A G E +++A+
Sbjct: 198 KKKGSGEADKDPSGSPASARKSPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAAT 257
Query: 219 GSEKLFAPGTDKGPALEKSEAKAGPVPKV 247
+K G KG +K++ + P P V
Sbjct: 258 VIKKSNQKGKAKGKGKKKAKEERAPSPPV 286
Score = 30.4 bits (67), Expect = 9.1
Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 21/131 (16%)
Query: 744 PAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLL 803
P PPP P V ++E G+ + R +K S + P+G P S
Sbjct: 172 PDPPPKPLRV----------RNKEAPAGEGTKMRKTKKKG---SGEADKDPSGSPASARK 218
Query: 804 LRAQSELGRSGAP----AEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKE 859
A L G+P +++ P+ +EEAA + +++ G K KE
Sbjct: 219 SPAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKE 278
Query: 860 ERGEDEASEPP 870
ER A PP
Sbjct: 279 ER----APSPP 285
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/284 (25%), Positives = 94/284 (33%), Gaps = 38/284 (13%)
Query: 205 SCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPT 264
S S SGP + + AP + P S ++ P SG SR
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387
Query: 265 ASPA--PHAAPCPGPP--PGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPT--HVPASL 318
P PH+ P P P G +P+ P PPPP +G P H P +
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPM 447
Query: 319 GAFAGHSQAAANGLHGLSRSSSA----PLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQ 374
+ G S +G++ L + P+G+ P G P + L Q Q Q
Sbjct: 448 DQYLG-STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
Query: 375 LHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGAL 434
PP PPP + ASS LP ++ A+ PGA
Sbjct: 507 --------PPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA- 557
Query: 435 LRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGL-PPTPPAAPPP 477
Q T P P G+ PP PP APPP
Sbjct: 558 -----------------PQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Score = 38.5 bits (88), Expect = 0.033
Identities = 52/205 (25%), Positives = 71/205 (34%), Gaps = 49/205 (23%)
Query: 870 PAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYR 929
P G P P+ LG +G+ + +G+ P P G ++ PP P
Sbjct: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP--------PPMG---MMPPPPPP-- 484
Query: 930 DREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLART 989
P G P G L + P P + + S L + + + +
Sbjct: 485 ---PSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
Query: 990 PP-------AAAALGAP----------------PPLVTAAGPPTPPGPPRS---RTTPLG 1023
PP AAA+ GAP PPL A PP PP PP S P G
Sbjct: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRG 601
Query: 1024 GLGPG-EARDYS------PSRNPPE 1041
G GP E+ D+ P R P +
Sbjct: 602 GDGPSHESEDFPRPLVTLPGRQPQQ 626
Score = 37.0 bits (84), Expect = 0.097
Identities = 42/170 (24%), Positives = 59/170 (34%), Gaps = 17/170 (10%)
Query: 242 GPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQP 301
G P SG+ R + + +P P P P PP G P PP + P
Sbjct: 452 GSTPVGSGVYRLHQ--GKGMMPPP-PMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPP 508
Query: 302 PPPQPRGLL--PTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPH 359
PPP P + T +P + A + + +A + SP P
Sbjct: 509 PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA-------AAASPGAPQMQ 561
Query: 360 LSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLP--GHPADHE 407
+ + + L Q L APP PPPP A ++ P G HE
Sbjct: 562 GNPTMVPLPPGVQPPLPP---GAPPPPPPPPPGSAGMMIPPRGGDGPSHE 608
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/284 (25%), Positives = 94/284 (33%), Gaps = 38/284 (13%)
Query: 205 SCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPT 264
S S SGP + + AP + P S ++ P SG SR
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387
Query: 265 ASPA--PHAAPCPGPP--PGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPT--HVPASL 318
P PH+ P P P G +P+ P PPPP +G P H P +
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPM 447
Query: 319 GAFAGHSQAAANGLHGLSRSSSA----PLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQ 374
+ G S +G++ L + P+G+ P G P + L Q Q Q
Sbjct: 448 DQYLG-STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
Query: 375 LHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGAL 434
PP PPP + ASS LP ++ A+ PGA
Sbjct: 507 --------PPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA- 557
Query: 435 LRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGL-PPTPPAAPPP 477
Q T P P G+ PP PP APPP
Sbjct: 558 -----------------PQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Score = 40.0 bits (92), Expect = 0.011
Identities = 46/179 (25%), Positives = 59/179 (32%), Gaps = 32/179 (17%)
Query: 242 GPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQP 301
G P SG+ R + + +P P P P PP G P PP + P
Sbjct: 452 GSTPVGSGVYRLHQ--GKGMMPPP-PMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPP 508
Query: 302 PPPQPRGLLPTHVP-------------ASLGAFA--GHSQAAANGLHGL----SRSSSAP 342
PPP P + + P A G+ QAAA G + P
Sbjct: 509 PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVP 568
Query: 343 LGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPG 401
L G L P P P A M APP PPPP P++ + + G
Sbjct: 569 LPPGVQPPLPPGAPPP----------PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMG 617
Score = 34.3 bits (77), Expect = 0.63
Identities = 47/187 (25%), Positives = 64/187 (34%), Gaps = 36/187 (19%)
Query: 870 PAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYR 929
P G P P+ LG +G+ + +G+ P P G ++ PP P
Sbjct: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP--------PPMG---MMPPPPPP-- 484
Query: 930 DREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLART 989
P G P G L + P P + + S L + + + +
Sbjct: 485 ---PSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
Query: 990 PP-------AAAALGAPP--------PLVTAAGPPTPPG-PPRSRTTPLGGLGPGEARDY 1033
PP AAA+ GAP PL PP PPG PP P G G Y
Sbjct: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAG----MMY 597
Query: 1034 SPSRNPP 1040
+P PP
Sbjct: 598 APPPPPP 604
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 54.7 bits (130), Expect = 4e-07
Identities = 107/427 (25%), Positives = 139/427 (32%), Gaps = 88/427 (20%)
Query: 117 KKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDS 176
K P PP +P+E P + PG E A A + + + S G D
Sbjct: 616 KAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDD 675
Query: 177 DDD----SVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGP 232
+D ++ EA + R S + V R Y C S P + AP GP
Sbjct: 676 AEDDPSRTLCEACNIR--FSRHETYTVHKR-YYCASRHDPPPRRPA------APPGPPGP 726
Query: 233 ALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP 292
A + + A PV R R+L HAA P PPP A P
Sbjct: 727 AAPPAPSPAAPV----RTRRRRKLY----------ELHAAGAPPPPPPGHA--------P 764
Query: 293 APHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLS 352
AP P GL P P AA+G LS+ PL
Sbjct: 765 APESPRPGSGSGSGPGLAPARSPG----------PAADGPIDLSKKPRRPL--------- 805
Query: 353 PHGPGPHLSTSHLALRSQAQ-HQLHAAMF---AAPPTLPPPPALPASSLVLPGHPADHEL 408
P P P L+ H + H L A + + P PPP AL + P P +
Sbjct: 806 PGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGP- 864
Query: 409 LRQELNTRFLVQSAERPGASL-GPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGL 467
+R +L F + GA L GPG R + AP PA
Sbjct: 865 VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSP---------------APAPAAS 909
Query: 468 PPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP--GPFGSLQGAF 525
P P + P D P+ P P PP+ P +P P P S +G
Sbjct: 910 P--QPGSRGPRDGLGPEPQEPP---------PGPPPSPAAAPEAVPPPPAPPSYSDKGVQ 958
Query: 526 QPKVSDP 532
P P
Sbjct: 959 TPSKGTP 965
Score = 38.5 bits (88), Expect = 0.033
Identities = 59/225 (26%), Positives = 73/225 (32%), Gaps = 42/225 (18%)
Query: 815 APAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGL 874
AP + A R K PA+ + PA P S PG E G A+ P G
Sbjct: 605 APEDAPAARRPKAPPGPARAPPGQ-PAEPDAPRSSPGPG----AREEGAGGAATPEDGAG 659
Query: 875 HPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPH 934
G G E +PG + + + P R A S + Y H
Sbjct: 660 -------GRGSEGSQSPGSSVDDAE--DDPSRTLCEACNIRFSRHETYTVHKRYYCASRH 710
Query: 935 GYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAA 994
P R P PP P G P P SPAA R
Sbjct: 711 DPPPRR----------PAAPPGPP---GPAAP-------PAPSPAAPVRTRRRRKLYELH 750
Query: 995 ALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNP 1039
A GAPPP PPG + +P G G G +P+R+P
Sbjct: 751 AAGAPPP--------PPPGHAPAPESPRPGSGSGSGPGLAPARSP 787
Score = 36.2 bits (82), Expect = 0.17
Identities = 62/241 (25%), Positives = 82/241 (34%), Gaps = 40/241 (16%)
Query: 810 LGRSGAPAEREAEPRVKESRSPAKEEAAKM--PARASPPHSKAAPGDVKVKEERGEDEAS 867
L ++G +E A PR + + + EAA + P P P R + E S
Sbjct: 446 LAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELS 505
Query: 868 EPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERP 927
P G P P +LGL GA L LP+ F A P S L + E
Sbjct: 506 SPTPGS-SPVPGELGLA----GA----------LFLPQYVFGPDAAPPASEILAKMSELV 550
Query: 928 YRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLA 987
+ R G G + P P A + + F ++ +H L
Sbjct: 551 H-SRLQQGAGAGA--GGAQTGLFPGAPKGATCFECEIT-------FSNVNNYYVHKRLYC 600
Query: 988 ---RTP---PAAAALGAPPPLVTAAGPP-TPPGPPRSRTTPLGGLGPGEARDYSPSRNPP 1040
R P PAA APP GP PPG P P GPG + + P
Sbjct: 601 SGRRAPEDAPAARRPKAPP------GPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATP 654
Query: 1041 E 1041
E
Sbjct: 655 E 655
Score = 35.8 bits (81), Expect = 0.22
Identities = 97/425 (22%), Positives = 125/425 (29%), Gaps = 102/425 (24%)
Query: 638 AGFHYPQDLA---RPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGS 694
+G P+D RP P A P P P A S P +R GG +
Sbjct: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSS-------PGPGAREEGAGGAAT 653
Query: 695 LSSHAFGGLGSH-ALAPGGSIFAPKEGSS------VHGLPSPHEAWN--------RLHRA 739
A GG GS + +PG S+ ++ S + S HE + H
Sbjct: 654 PEDGA-GGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDP 712
Query: 740 PPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPV 799
PP PA PP P A PA PV
Sbjct: 713 PPRRPAAPPGPPG----------------------------------PAAPPAPSPAAPV 738
Query: 800 SGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKE 859
R EL +GAP P +PA E + P S AP
Sbjct: 739 RTRRRRKLYELHAAGAP------PPPPPGHAPAPE--SPRPGSGSGSGPGLAPARSPGPA 790
Query: 860 ERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAA 919
G + S+ P L AP A ++ ++ AAP PG+
Sbjct: 791 ADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALG 850
Query: 920 LLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPA 979
L A P+ PP P + G LL H L
Sbjct: 851 -------------------------LPAAACPYCPPNGP-VRGDLLEHFRLAHGLLLGAP 884
Query: 980 ALHNGLLARTP----PAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSP 1035
G+ ARTP P+ A A P + GP GP P GP + +P
Sbjct: 885 LAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPP----GPPPSPAAAP 940
Query: 1036 SRNPP 1040
PP
Sbjct: 941 EAVPP 945
Score = 33.5 bits (75), Expect = 1.1
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 10/138 (7%)
Query: 268 APHAAPC---PGPPPG-SRANPLVKKEPPAPHRHTPQPPPPQP-RGLLPTHVPASLGAFA 322
AP AP P PPG +RA P EP AP R +P P + G T + G +
Sbjct: 605 APEDAPAARRPKAPPGPARAPPGQPAEPDAP-RSSPGPGAREEGAGGAATPEDGAGGRGS 663
Query: 323 GHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAA 382
SQ+ + + S L ++ S H T H ++H AA
Sbjct: 664 EGSQSPGSSVDDAEDDPSRTLCEACNIRFSRH----ETYTVHKRYYCASRHDPPPRRPAA 719
Query: 383 PPTLPPPPALPASSLVLP 400
PP P P A PA S P
Sbjct: 720 PPGPPGPAAPPAPSPAAP 737
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 10/126 (7%)
Query: 804 LRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGE 863
+ A+ E+ GA + E + E+ SP + P PP S P +++ +E
Sbjct: 19 MEAREEVQLVGA-SHMEQKATAPEAPSPPSADV-NSPPPLPPPTSPGGPKELEGQEPEPR 76
Query: 864 DEASEPPAGGLHPAPLQLGL--GRERLGA-----PGFAWEPFRGLELPRRAFP-AAAPAP 915
EP + P L+ + G+ R+ A G +W PF G R + P A P+P
Sbjct: 77 PTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSP 136
Query: 916 GSAALL 921
LL
Sbjct: 137 ALTLLL 142
Score = 32.3 bits (72), Expect = 2.4
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 11/87 (12%)
Query: 231 GPALE-KSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKK 289
GP +E ++ A GP P + S + + P P P PGPPP A P
Sbjct: 887 GPGVEARTPADRGPSPAPAPAA-SPQPGSRGPRDGLGPEPQEPP-PGPPPSPAAAPEAVP 944
Query: 290 EPPAPHRHTPQ--------PPPPQPRG 308
PPAP ++ + P P P G
Sbjct: 945 PPPAPPSYSDKGVQTPSKGTPAPLPNG 971
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 54.7 bits (130), Expect = 4e-07
Identities = 69/274 (25%), Positives = 104/274 (37%), Gaps = 29/274 (10%)
Query: 772 KEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSP 831
KEE L R + + T S + Q E+ R +P+E E E +SRS
Sbjct: 83 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ-EISRPNSPSEGEGES--SDSRS- 138
Query: 832 AKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEAS--------EPPA----GGLHPAPL 879
+E + P + +P ++ + ++S +PPA G+ PAP
Sbjct: 139 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 198
Query: 880 QLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPE 939
G +L PG +P + P A+ AP + P P PH + +
Sbjct: 199 SAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQP---QAPTAPV----PHTHIQQ 248
Query: 940 RLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP 999
+R +PH PP P+ L P G+ P +P+ L + PP +L A
Sbjct: 249 APALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 306
Query: 1000 PPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDY 1033
P L+ GPP P G P + LG A Y
Sbjct: 307 P-LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 339
Score = 51.2 bits (121), Expect = 5e-06
Identities = 178/800 (22%), Positives = 251/800 (31%), Gaps = 170/800 (21%)
Query: 89 SFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEP 148
S STL + K P R + R S + ++++ S + E
Sbjct: 26 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE 85
Query: 149 ACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDS 208
A PL+ +K+ + V+ D + D + + T +++ +S G G S DS
Sbjct: 86 ASS-----PLKSNKRQREKVAS--DTEEADRTSSKKTKTQEISRPNSPS--EGEGESSDS 136
Query: 209 ESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPA 268
S D+ +S D + + + + +P E + SA+ + A P
Sbjct: 137 RSVNDEGSS-----------DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
Query: 269 PHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAA 328
AP P S A P TPQ P P P A
Sbjct: 186 ALQAPTGVTPAPSSAPP-----------GTPQLPTPGPT-----------------PSAT 217
Query: 329 ANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPP 388
A G +S AP + +P P PH +H+ Q LH PP+ P
Sbjct: 218 AVPPQGSPTASQAP-----NQPQAPTAPVPH---THI----QQAPALHPQR---PPSPHP 262
Query: 389 PPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQH 448
PP HP+ H L+ L SA +P A + + H H
Sbjct: 263 PP-----------HPSPHPPLQP------LTGSAGQPSAP----SHAQPPLHGQGPPGPH 301
Query: 449 THQHTHQHQHTFAPFPAGLPP----------TPPAAPPPFDKYAPKLDSPYFRHSSVSFF 498
+ Q QH P P GLPP T PAA P L P + + S
Sbjct: 302 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS----LQLPASQSALQSQQ 357
Query: 499 PSFPPAIPGLPTLLPH--PGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPG 556
P +P P +PH P P + P++ P P+ +PP
Sbjct: 358 PPREQPLPPAPLAMPHIKPPPTTPI-----PQLPAPQAHKHPPHLSGPSPFSMNANLPP- 411
Query: 557 RPRGARDSRSLQKTWVGVA-PAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLD 615
P + SL A P PL Q+ Q +
Sbjct: 412 -PPALKPLSSLSTHHPPSAHPPPL---------------------QLMPQSQPLPSSPAQ 449
Query: 616 PHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP 675
P L L PPA G H Q +P F A +PF P P P
Sbjct: 450 PPGLTQSQNLP---PPPASHPPTGLH--QVAPQPPF--------AQHPFVPGGPPPITPP 496
Query: 676 TGPLTD-PFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWN 734
T P T P + P T + A GG ++A G S P L E
Sbjct: 497 TCPSTSTPPAGPGTSAQPPCSGAAASGG----SIAGGSSCPLPTVQIKEEALDDAEEP-- 550
Query: 735 RLHRAPPSFPAPPPWPKSVDA-ERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPAT 793
PP +P P P VD S + D G R L
Sbjct: 551 --ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM---------- 598
Query: 794 PAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPG 853
P++G L + E + A+REAE + +E R KE+ + + A
Sbjct: 599 ----PLAGSKLAKKRE--EAIEKAKREAEQKAREEREREKEKEKERERERE--REREAER 650
Query: 854 DVKVKEERGEDEASEPPAGG 873
K E S+P G
Sbjct: 651 AAKASSSAHEGRLSDPQLSG 670
Score = 50.8 bits (120), Expect = 6e-06
Identities = 137/550 (24%), Positives = 176/550 (32%), Gaps = 155/550 (28%)
Query: 12 RAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRR 71
R +R RG R R + P+S D SP E+ G AA +
Sbjct: 19 RTRRSRGSM-STLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAASTSSNDSKAETVK 76
Query: 72 RESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPS 131
+ + +EE + S L++ K K E+ +R KK + E P PS
Sbjct: 77 KSAKKVKEE--------ASSPLKS-NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPS 127
Query: 132 ENRRPL--------EAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLE 183
E E S +D++ D P PS Q D +SD DS
Sbjct: 128 EGEGESSDSRSVNDEGSSDPKDIDQ--DNRSTSPSIPSPQ---------DNESDSDS--- 173
Query: 184 ATSSRDPLSDSSAHAVSG-RGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAG 242
S++ + + A+ G + S P PGT + P G
Sbjct: 174 --SAQQQMLQAQPPALQAPTGVTPAPSSAP-------------PGTPQLPT-------PG 211
Query: 243 PVPKVSGLERSRELSAESFLPTASPA---------------------------PHAAPCP 275
P P SA + P SP P P P
Sbjct: 212 PTP-----------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 260
Query: 276 GPPP------------GSRAN---------PLVKKEPPAPHR-----HTPQPPPPQPRGL 309
PPP GS PL + PP PH P PPQP GL
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320
Query: 310 LPTHVPASLG-AFAGHSQAAANGLHGLSRSSS-----------------APLGLGKHVSL 351
P AS G A G S AAA L +S APL + H+
Sbjct: 321 PP---QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM-PHIKP 376
Query: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL-PASSLVLPGHPADHELLR 410
P P P L H + F+ LPPPPAL P SSL P+ H
Sbjct: 377 PPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL 434
Query: 411 QELNTRFLVQSAERPGASLGPGALLRAE-FHQHQHTHQHTHQHTHQHQHTFA--PFPAGL 467
Q + QS P + P L +++ +H T H Q FA PF G
Sbjct: 435 Q-----LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Query: 468 PP--TPPAAP 475
PP TPP P
Sbjct: 490 PPPITPPTCP 499
Score = 48.5 bits (114), Expect = 3e-05
Identities = 81/326 (24%), Positives = 112/326 (34%), Gaps = 59/326 (18%)
Query: 727 PSPHEAWNRLHRAPPSFPAPPP--WPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTR 784
PSPH PP P+P P P + A + SA +H + P +G+ L+
Sbjct: 258 PSPH---------PPPHPSPHPPLQPLTGSAGQPSA-PSHAQPPLHGQGPPGPHSLQAGP 307
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPA------EREAEPRVKESRSPAKEEAAK 838
LL P P G P + Q+ LG S A A + A +S+ P +E+
Sbjct: 308 LLQHPGPPQPFGLPPQA--SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 365
Query: 839 MPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPF 898
PA + PH K P + + P G P + L P A +P
Sbjct: 366 -PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL------PPPPALKPL 418
Query: 899 RGLEL---------PRRAFPAAAPAPGSAAL---------LEPPERPYRDREPHGYSPER 940
L P + P + P P S A L PP + H +P+
Sbjct: 419 SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 478
Query: 941 LRGELERARAPHLPPAAPALDGALLPSL-------GALHFPRLSPAALHNGLLA--RTPP 991
A+ P +P P + PS G P S AA G +A + P
Sbjct: 479 -----PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 533
Query: 992 AAAALGAPPPLVTAAGPPTPPGPPRS 1017
L A P +PP PPRS
Sbjct: 534 LPTVQIKEEALDDAEEPESPPPPPRS 559
Score = 39.3 bits (90), Expect = 0.020
Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 50/188 (26%)
Query: 358 PHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPP---------ALPASSLVLPGHPADHEL 408
P L H A H+A+ PPT P P L L L G E+
Sbjct: 778 PELDPLHPAANPMEHFARHSAL-TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEM 836
Query: 409 LRQELNTRFLVQSAERPGASLGPGALLRAEF-----HQHQHTHQHTHQHTHQ----HQHT 459
+ + AER ASL L R + H HQH+H H+H H HQ HQ +
Sbjct: 837 SYPDRLAAERIH-AERM-ASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 894
Query: 460 FA------------------PFPAGLPPTPPAAPPPFDKYA---PKLDSPYFRHSSVSFF 498
P+P G P P PP + P +PY R
Sbjct: 895 AGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPR------- 947
Query: 499 PSFPPAIP 506
P AIP
Sbjct: 948 -DLPGAIP 954
Score = 35.4 bits (80), Expect = 0.28
Identities = 63/252 (25%), Positives = 87/252 (34%), Gaps = 59/252 (23%)
Query: 232 PALEKSEAKAGPV-PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSR-----ANP 285
P E + P+ P + +E SA + PTA P P A+ PG P R A P
Sbjct: 771 PGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGP 830
Query: 286 LVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAG----------HSQAAANGLHGL 335
++ E P R + + L + A L F HS + L
Sbjct: 831 QLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPL 890
Query: 336 SRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP-TLPPPPALPA 394
+ S+ P+ H + P GPHL A F PP TLP P
Sbjct: 891 HQGSAGPV----HPLVDPLTAGPHL-----------------ARFPYPPGTLPNP----- 924
Query: 395 SSLVLPGHPADHELLRQEL-NTRFLVQSAERPGASLGPGALLR---------AEFHQHQH 444
+L P +HE+LR + T + + PGA P + AE +
Sbjct: 925 ---LLGQPPHEHEMLRHPVFGTPY---PRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAM 978
Query: 445 THQHTHQHTHQH 456
Q H H H H
Sbjct: 979 EQQWLHGHPHMH 990
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 54.7 bits (130), Expect = 4e-07
Identities = 69/274 (25%), Positives = 104/274 (37%), Gaps = 29/274 (10%)
Query: 772 KEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSP 831
KEE L R + + T S + Q E+ R +P+E E E +SRS
Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ-EISRPNSPSEGEGES--SDSRS- 692
Query: 832 AKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEAS--------EPPA----GGLHPAPL 879
+E + P + +P ++ + ++S +PPA G+ PAP
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 752
Query: 880 QLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPE 939
G +L PG +P + P A+ AP + P P PH + +
Sbjct: 753 SAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQP---QAPTAPV----PHTHIQQ 802
Query: 940 RLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP 999
+R +PH PP P+ L P G+ P +P+ L + PP +L A
Sbjct: 803 APALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 860
Query: 1000 PPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDY 1033
P L+ GPP P G P + LG A Y
Sbjct: 861 P-LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Score = 51.2 bits (121), Expect = 5e-06
Identities = 178/800 (22%), Positives = 251/800 (31%), Gaps = 170/800 (21%)
Query: 89 SFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEP 148
S STL + K P R + R S + ++++ S + E
Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE 639
Query: 149 ACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDS 208
A PL+ +K+ + V+ D + D + + T +++ +S G G S DS
Sbjct: 640 ASS-----PLKSNKRQREKVAS--DTEEADRTSSKKTKTQEISRPNSPS--EGEGESSDS 690
Query: 209 ESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPA 268
S D+ +S D + + + + +P E + SA+ + A P
Sbjct: 691 RSVNDEGSS-----------DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 269 PHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAA 328
AP P S A P TPQ P P P A
Sbjct: 740 ALQAPTGVTPAPSSAPP-----------GTPQLPTPGPT-----------------PSAT 771
Query: 329 ANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPP 388
A G +S AP + +P P PH +H+ Q LH PP+ P
Sbjct: 772 AVPPQGSPTASQAP-----NQPQAPTAPVPH---THI----QQAPALHPQR---PPSPHP 816
Query: 389 PPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQH 448
PP HP+ H L+ L SA +P A + + H H
Sbjct: 817 PP-----------HPSPHPPLQP------LTGSAGQPSAP----SHAQPPLHGQGPPGPH 855
Query: 449 THQHTHQHQHTFAPFPAGLPP----------TPPAAPPPFDKYAPKLDSPYFRHSSVSFF 498
+ Q QH P P GLPP T PAA P L P + + S
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS----LQLPASQSALQSQQ 911
Query: 499 PSFPPAIPGLPTLLPH--PGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPG 556
P +P P +PH P P + P++ P P+ +PP
Sbjct: 912 PPREQPLPPAPLAMPHIKPPPTTPI-----PQLPAPQAHKHPPHLSGPSPFSMNANLPP- 965
Query: 557 RPRGARDSRSLQKTWVGVA-PAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLD 615
P + SL A P PL Q+ Q +
Sbjct: 966 -PPALKPLSSLSTHHPPSAHPPPL---------------------QLMPQSQPLPSSPAQ 1003
Query: 616 PHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP 675
P L L PPA G H Q +P F A +PF P P P
Sbjct: 1004 PPGLTQSQNLP---PPPASHPPTGLH--QVAPQPPF--------AQHPFVPGGPPPITPP 1050
Query: 676 TGPLTD-PFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWN 734
T P T P + P T + A GG ++A G S P L E
Sbjct: 1051 TCPSTSTPPAGPGTSAQPPCSGAAASGG----SIAGGSSCPLPTVQIKEEALDDAEEP-- 1104
Query: 735 RLHRAPPSFPAPPPWPKSVDA-ERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPAT 793
PP +P P P VD S + D G R L
Sbjct: 1105 --ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM---------- 1152
Query: 794 PAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPG 853
P++G L + E + A+REAE + +E R KE+ + + A
Sbjct: 1153 ----PLAGSKLAKKRE--EAIEKAKREAEQKAREEREREKEKEKERERERE--REREAER 1204
Query: 854 DVKVKEERGEDEASEPPAGG 873
K E S+P G
Sbjct: 1205 AAKASSSAHEGRLSDPQLSG 1224
Score = 50.8 bits (120), Expect = 6e-06
Identities = 137/550 (24%), Positives = 176/550 (32%), Gaps = 155/550 (28%)
Query: 12 RAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRR 71
R +R RG R R + P+S D SP E+ G AA +
Sbjct: 573 RTRRSRGSM-STLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAASTSSNDSKAETVK 630
Query: 72 RESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPS 131
+ + +EE + S L++ K K E+ +R KK + E P PS
Sbjct: 631 KSAKKVKEE--------ASSPLKS-NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPS 681
Query: 132 ENRRPL--------EAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLE 183
E E S +D++ D P PS Q D +SD DS
Sbjct: 682 EGEGESSDSRSVNDEGSSDPKDIDQ--DNRSTSPSIPSPQ---------DNESDSDS--- 727
Query: 184 ATSSRDPLSDSSAHAVSG-RGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAG 242
S++ + + A+ G + S P PGT + P G
Sbjct: 728 --SAQQQMLQAQPPALQAPTGVTPAPSSAP-------------PGTPQLPT-------PG 765
Query: 243 PVPKVSGLERSRELSAESFLPTASPA---------------------------PHAAPCP 275
P P SA + P SP P P P
Sbjct: 766 PTP-----------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 276 GPPP------------GSRAN---------PLVKKEPPAPHR-----HTPQPPPPQPRGL 309
PPP GS PL + PP PH P PPQP GL
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 310 LPTHVPASLG-AFAGHSQAAANGLHGLSRSSS-----------------APLGLGKHVSL 351
P AS G A G S AAA L +S APL + H+
Sbjct: 875 PP---QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM-PHIKP 930
Query: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL-PASSLVLPGHPADHELLR 410
P P P L H + F+ LPPPPAL P SSL P+ H
Sbjct: 931 PPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL 988
Query: 411 QELNTRFLVQSAERPGASLGPGALLRAE-FHQHQHTHQHTHQHTHQHQHTFA--PFPAGL 467
Q + QS P + P L +++ +H T H Q FA PF G
Sbjct: 989 Q-----LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 468 PP--TPPAAP 475
PP TPP P
Sbjct: 1044 PPPITPPTCP 1053
Score = 48.5 bits (114), Expect = 3e-05
Identities = 81/326 (24%), Positives = 112/326 (34%), Gaps = 59/326 (18%)
Query: 727 PSPHEAWNRLHRAPPSFPAPPP--WPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTR 784
PSPH PP P+P P P + A + SA +H + P +G+ L+
Sbjct: 812 PSPH---------PPPHPSPHPPLQPLTGSAGQPSA-PSHAQPPLHGQGPPGPHSLQAGP 861
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPA------EREAEPRVKESRSPAKEEAAK 838
LL P P G P + Q+ LG S A A + A +S+ P +E+
Sbjct: 862 LLQHPGPPQPFGLPPQA--SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919
Query: 839 MPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPF 898
PA + PH K P + + P G P + L P A +P
Sbjct: 920 -PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL------PPPPALKPL 972
Query: 899 RGLEL---------PRRAFPAAAPAPGSAAL---------LEPPERPYRDREPHGYSPER 940
L P + P + P P S A L PP + H +P+
Sbjct: 973 SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032
Query: 941 LRGELERARAPHLPPAAPALDGALLPSL-------GALHFPRLSPAALHNGLLA--RTPP 991
A+ P +P P + PS G P S AA G +A + P
Sbjct: 1033 -----PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 1087
Query: 992 AAAALGAPPPLVTAAGPPTPPGPPRS 1017
L A P +PP PPRS
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPPRS 1113
Score = 39.3 bits (90), Expect = 0.020
Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 50/188 (26%)
Query: 358 PHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPP---------ALPASSLVLPGHPADHEL 408
P L H A H+A+ PPT P P L L L G E+
Sbjct: 1332 PELDPLHPAANPMEHFARHSAL-TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEM 1390
Query: 409 LRQELNTRFLVQSAERPGASLGPGALLRAEF-----HQHQHTHQHTHQHTHQ----HQHT 459
+ + AER ASL L R + H HQH+H H+H H HQ HQ +
Sbjct: 1391 SYPDRLAAERIH-AERM-ASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 1448
Query: 460 FA------------------PFPAGLPPTPPAAPPPFDKYA---PKLDSPYFRHSSVSFF 498
P+P G P P PP + P +PY R
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPR------- 1501
Query: 499 PSFPPAIP 506
P AIP
Sbjct: 1502 -DLPGAIP 1508
Score = 35.4 bits (80), Expect = 0.28
Identities = 63/252 (25%), Positives = 87/252 (34%), Gaps = 59/252 (23%)
Query: 232 PALEKSEAKAGPV-PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSR-----ANP 285
P E + P+ P + +E SA + PTA P P A+ PG P R A P
Sbjct: 1325 PGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGP 1384
Query: 286 LVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAG----------HSQAAANGLHGL 335
++ E P R + + L + A L F HS + L
Sbjct: 1385 QLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPL 1444
Query: 336 SRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP-TLPPPPALPA 394
+ S+ P+ H + P GPHL A F PP TLP P
Sbjct: 1445 HQGSAGPV----HPLVDPLTAGPHL-----------------ARFPYPPGTLPNP----- 1478
Query: 395 SSLVLPGHPADHELLRQEL-NTRFLVQSAERPGASLGPGALLR---------AEFHQHQH 444
+L P +HE+LR + T + + PGA P + AE +
Sbjct: 1479 ---LLGQPPHEHEMLRHPVFGTPY---PRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAM 1532
Query: 445 THQHTHQHTHQH 456
Q H H H H
Sbjct: 1533 EQQWLHGHPHMH 1544
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 54.7 bits (130), Expect = 4e-07
Identities = 69/274 (25%), Positives = 104/274 (37%), Gaps = 29/274 (10%)
Query: 772 KEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSP 831
KEE L R + + T S + Q E+ R +P+E E E +SRS
Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ-EISRPNSPSEGEGES--SDSRS- 692
Query: 832 AKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEAS--------EPPA----GGLHPAPL 879
+E + P + +P ++ + ++S +PPA G+ PAP
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 752
Query: 880 QLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPE 939
G +L PG +P + P A+ AP + P P PH + +
Sbjct: 753 SAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQP---QAPTAPV----PHTHIQQ 802
Query: 940 RLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAP 999
+R +PH PP P+ L P G+ P +P+ L + PP +L A
Sbjct: 803 APALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 860
Query: 1000 PPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDY 1033
P L+ GPP P G P + LG A Y
Sbjct: 861 P-LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Score = 51.2 bits (121), Expect = 5e-06
Identities = 178/800 (22%), Positives = 251/800 (31%), Gaps = 170/800 (21%)
Query: 89 SFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEP 148
S STL + K P R + R S + ++++ S + E
Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEE 639
Query: 149 ACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDS 208
A PL+ +K+ + V+ D + D + + T +++ +S G G S DS
Sbjct: 640 ASS-----PLKSNKRQREKVAS--DTEEADRTSSKKTKTQEISRPNSPS--EGEGESSDS 690
Query: 209 ESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPA 268
S D+ +S D + + + + +P E + SA+ + A P
Sbjct: 691 RSVNDEGSS-----------DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 269 PHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAA 328
AP P S A P TPQ P P P A
Sbjct: 740 ALQAPTGVTPAPSSAPP-----------GTPQLPTPGPT-----------------PSAT 771
Query: 329 ANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPP 388
A G +S AP + +P P PH +H+ Q LH PP+ P
Sbjct: 772 AVPPQGSPTASQAP-----NQPQAPTAPVPH---THI----QQAPALHPQR---PPSPHP 816
Query: 389 PPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQH 448
PP HP+ H L+ L SA +P A + + H H
Sbjct: 817 PP-----------HPSPHPPLQP------LTGSAGQPSAP----SHAQPPLHGQGPPGPH 855
Query: 449 THQHTHQHQHTFAPFPAGLPP----------TPPAAPPPFDKYAPKLDSPYFRHSSVSFF 498
+ Q QH P P GLPP T PAA P L P + + S
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS----LQLPASQSALQSQQ 911
Query: 499 PSFPPAIPGLPTLLPH--PGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPG 556
P +P P +PH P P + P++ P P+ +PP
Sbjct: 912 PPREQPLPPAPLAMPHIKPPPTTPI-----PQLPAPQAHKHPPHLSGPSPFSMNANLPP- 965
Query: 557 RPRGARDSRSLQKTWVGVA-PAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLD 615
P + SL A P PL Q+ Q +
Sbjct: 966 -PPALKPLSSLSTHHPPSAHPPPL---------------------QLMPQSQPLPSSPAQ 1003
Query: 616 PHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP 675
P L L PPA G H Q +P F A +PF P P P
Sbjct: 1004 PPGLTQSQNLP---PPPASHPPTGLH--QVAPQPPF--------AQHPFVPGGPPPITPP 1050
Query: 676 TGPLTD-PFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWN 734
T P T P + P T + A GG ++A G S P L E
Sbjct: 1051 TCPSTSTPPAGPGTSAQPPCSGAAASGG----SIAGGSSCPLPTVQIKEEALDDAEEP-- 1104
Query: 735 RLHRAPPSFPAPPPWPKSVDA-ERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPAT 793
PP +P P P VD S + D G R L
Sbjct: 1105 --ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFM---------- 1152
Query: 794 PAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPG 853
P++G L + E + A+REAE + +E R KE+ + + A
Sbjct: 1153 ----PLAGSKLAKKRE--EAIEKAKREAEQKAREEREREKEKEKERERERE--REREAER 1204
Query: 854 DVKVKEERGEDEASEPPAGG 873
K E S+P G
Sbjct: 1205 AAKASSSAHEGRLSDPQLSG 1224
Score = 50.8 bits (120), Expect = 6e-06
Identities = 137/550 (24%), Positives = 176/550 (32%), Gaps = 155/550 (28%)
Query: 12 RAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRR 71
R +R RG R R + P+S D SP E+ G AA +
Sbjct: 573 RTRRSRGSM-STLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAASTSSNDSKAETVK 630
Query: 72 RESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPS 131
+ + +EE + S L++ K K E+ +R KK + E P PS
Sbjct: 631 KSAKKVKEE--------ASSPLKS-NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPS 681
Query: 132 ENRRPL--------EAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLE 183
E E S +D++ D P PS Q D +SD DS
Sbjct: 682 EGEGESSDSRSVNDEGSSDPKDIDQ--DNRSTSPSIPSPQ---------DNESDSDS--- 727
Query: 184 ATSSRDPLSDSSAHAVSG-RGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAG 242
S++ + + A+ G + S P PGT + P G
Sbjct: 728 --SAQQQMLQAQPPALQAPTGVTPAPSSAP-------------PGTPQLPT-------PG 765
Query: 243 PVPKVSGLERSRELSAESFLPTASPA---------------------------PHAAPCP 275
P P SA + P SP P P P
Sbjct: 766 PTP-----------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 276 GPPP------------GSRAN---------PLVKKEPPAPHR-----HTPQPPPPQPRGL 309
PPP GS PL + PP PH P PPQP GL
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 310 LPTHVPASLG-AFAGHSQAAANGLHGLSRSSS-----------------APLGLGKHVSL 351
P AS G A G S AAA L +S APL + H+
Sbjct: 875 PP---QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM-PHIKP 930
Query: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPAL-PASSLVLPGHPADHELLR 410
P P P L H + F+ LPPPPAL P SSL P+ H
Sbjct: 931 PPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL 988
Query: 411 QELNTRFLVQSAERPGASLGPGALLRAE-FHQHQHTHQHTHQHTHQHQHTFA--PFPAGL 467
Q + QS P + P L +++ +H T H Q FA PF G
Sbjct: 989 Q-----LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 468 PP--TPPAAP 475
PP TPP P
Sbjct: 1044 PPPITPPTCP 1053
Score = 48.5 bits (114), Expect = 3e-05
Identities = 81/326 (24%), Positives = 112/326 (34%), Gaps = 59/326 (18%)
Query: 727 PSPHEAWNRLHRAPPSFPAPPP--WPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTR 784
PSPH PP P+P P P + A + SA +H + P +G+ L+
Sbjct: 812 PSPH---------PPPHPSPHPPLQPLTGSAGQPSA-PSHAQPPLHGQGPPGPHSLQAGP 861
Query: 785 LLSRASPATPAGHPVSGLLLRAQSELGRSGAPA------EREAEPRVKESRSPAKEEAAK 838
LL P P G P + Q+ LG S A A + A +S+ P +E+
Sbjct: 862 LLQHPGPPQPFGLPPQA--SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919
Query: 839 MPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPF 898
PA + PH K P + + P G P + L P A +P
Sbjct: 920 -PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL------PPPPALKPL 972
Query: 899 RGLEL---------PRRAFPAAAPAPGSAAL---------LEPPERPYRDREPHGYSPER 940
L P + P + P P S A L PP + H +P+
Sbjct: 973 SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032
Query: 941 LRGELERARAPHLPPAAPALDGALLPSL-------GALHFPRLSPAALHNGLLA--RTPP 991
A+ P +P P + PS G P S AA G +A + P
Sbjct: 1033 -----PFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 1087
Query: 992 AAAALGAPPPLVTAAGPPTPPGPPRS 1017
L A P +PP PPRS
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPPRS 1113
Score = 39.3 bits (90), Expect = 0.020
Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 50/188 (26%)
Query: 358 PHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPP---------ALPASSLVLPGHPADHEL 408
P L H A H+A+ PPT P P L L L G E+
Sbjct: 1332 PELDPLHPAANPMEHFARHSAL-TIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEM 1390
Query: 409 LRQELNTRFLVQSAERPGASLGPGALLRAEF-----HQHQHTHQHTHQHTHQ----HQHT 459
+ + AER ASL L R + H HQH+H H+H H HQ HQ +
Sbjct: 1391 SYPDRLAAERIH-AERM-ASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 1448
Query: 460 FA------------------PFPAGLPPTPPAAPPPFDKYA---PKLDSPYFRHSSVSFF 498
P+P G P P PP + P +PY R
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPR------- 1501
Query: 499 PSFPPAIP 506
P AIP
Sbjct: 1502 -DLPGAIP 1508
Score = 35.4 bits (80), Expect = 0.28
Identities = 63/252 (25%), Positives = 87/252 (34%), Gaps = 59/252 (23%)
Query: 232 PALEKSEAKAGPV-PKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSR-----ANP 285
P E + P+ P + +E SA + PTA P P A+ PG P R A P
Sbjct: 1325 PGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGP 1384
Query: 286 LVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAG----------HSQAAANGLHGL 335
++ E P R + + L + A L F HS + L
Sbjct: 1385 QLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPL 1444
Query: 336 SRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPP-TLPPPPALPA 394
+ S+ P+ H + P GPHL A F PP TLP P
Sbjct: 1445 HQGSAGPV----HPLVDPLTAGPHL-----------------ARFPYPPGTLPNP----- 1478
Query: 395 SSLVLPGHPADHELLRQEL-NTRFLVQSAERPGASLGPGALLR---------AEFHQHQH 444
+L P +HE+LR + T + + PGA P + AE +
Sbjct: 1479 ---LLGQPPHEHEMLRHPVFGTPY---PRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAM 1532
Query: 445 THQHTHQHTHQH 456
Q H H H H
Sbjct: 1533 EQQWLHGHPHMH 1544
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 54.3 bits (129), Expect = 6e-07
Identities = 106/453 (23%), Positives = 157/453 (34%), Gaps = 58/453 (12%)
Query: 4 KVRPSRRSRAQRDRGRRRE-AARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPR 62
K P SR Q +E +A + +SPS + S + + R + + R
Sbjct: 263 KKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGR 322
Query: 63 TARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRES 122
+ P RRR S + + + S ++++ + A H ++R + R S
Sbjct: 323 SPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHS 382
Query: 123 ETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGD-----RDSD 177
P P + E ++ A A K+ + SK V + + + +DS
Sbjct: 383 SISPVRLPLNSSLGAELSRKKKE-RAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSG 441
Query: 178 DDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDD---KASVGSEK-----LFAPGT- 228
+S S + S V+ + + ++ D K SEK L A GT
Sbjct: 442 LESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTR 501
Query: 229 DKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVK 288
D P K E PK + + E LPT + P P PPP P +
Sbjct: 502 DSKPIALKEEI---VTPKET---ETSEKETPPPLPTIASPPPPLPTTTPPP---QTPPLP 552
Query: 289 KEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKH 348
PP P PQ PP P + VPAS + S + +S P+ +
Sbjct: 553 PLPPIP--ALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVK 610
Query: 349 VSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALP------ASSLVLPGH 402
+S PHL TS L P LP PP LP + LP
Sbjct: 611 TQVSVTAAIPHLKTSTL------------------PPLPLPPLLPGDDDMDSPKETLPSK 652
Query: 403 PADHELLRQELNTRFLVQS----AERPGASLGP 431
P E +E TR L+ E PG L P
Sbjct: 653 PVKKE---KEQRTRHLLTDLPLPPELPGGDLSP 682
Score = 33.9 bits (76), Expect = 0.82
Identities = 60/272 (22%), Positives = 98/272 (36%), Gaps = 26/272 (9%)
Query: 781 EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPA-----KEE 835
E++ S SP+ P G S ++ L RS P+ + + R SRSPA
Sbjct: 314 ERSGSYSGRSPS-PYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR---SRSPAYSRHSSSH 369
Query: 836 AAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAW 895
+ K + + HS +P + + G + + + A ++ G+E G+P F
Sbjct: 370 SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD-GKESKGSPVF-- 426
Query: 896 EPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDR---EPHGYSPERLRGELERARAPH 952
LPR+ + + P ++ + + L E++ +
Sbjct: 427 -------LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTG 479
Query: 953 LPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPP 1012
+ L+ L A P AL ++ + PPPL T A PP PP
Sbjct: 480 KVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPP-PP 538
Query: 1013 GP---PRSRTTPLGGLGPGEARDYSPSRNPPE 1041
P P +T PL L P A P P +
Sbjct: 539 LPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQ 570
Score = 33.1 bits (74), Expect = 1.4
Identities = 55/233 (23%), Positives = 91/233 (39%), Gaps = 14/233 (6%)
Query: 638 AGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTF-GGLGSLS 696
+G Y QD L PS +H +SN PGS ++ P+ PS + S S
Sbjct: 238 SGASYGQDY--DLSPSR--SHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPS 293
Query: 697 SHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAE 756
++ + S + GS PSP+ R+ F + +S
Sbjct: 294 PYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGR----RRSSSPFLSKRSLSRSPLPS 349
Query: 757 RVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAP 816
R S + + R P + +++ SR S +P P++ L S + A
Sbjct: 350 RKS-MKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAA 408
Query: 817 AEREAEPRVKESR-SPA---KEEAAKMPARASPPHSKAAPGDVKVKEERGEDE 865
A A+ KES+ SP ++E + + A+ S SK P VK+++ + E
Sbjct: 409 AAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTE 461
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 54.3 bits (129), Expect = 6e-07
Identities = 106/453 (23%), Positives = 157/453 (34%), Gaps = 58/453 (12%)
Query: 4 KVRPSRRSRAQRDRGRRRE-AARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPR 62
K P SR Q +E +A + +SPS + S + + R + + R
Sbjct: 263 KKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGR 322
Query: 63 TARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRES 122
+ P RRR S + + + S ++++ + A H ++R + R S
Sbjct: 323 SPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHS 382
Query: 123 ETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGD-----RDSD 177
P P + E ++ A A K+ + SK V + + + +DS
Sbjct: 383 SISPVRLPLNSSLGAELSRKKKE-RAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSG 441
Query: 178 DDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDD---KASVGSEK-----LFAPGT- 228
+S S + S V+ + + ++ D K SEK L A GT
Sbjct: 442 LESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTR 501
Query: 229 DKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVK 288
D P K E PK + + E LPT + P P PPP P +
Sbjct: 502 DSKPIALKEEI---VTPKET---ETSEKETPPPLPTIASPPPPLPTTTPPP---QTPPLP 552
Query: 289 KEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKH 348
PP P PQ PP P + VPAS + S + +S P+ +
Sbjct: 553 PLPPIP--ALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVK 610
Query: 349 VSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALP------ASSLVLPGH 402
+S PHL TS L P LP PP LP + LP
Sbjct: 611 TQVSVTAAIPHLKTSTL------------------PPLPLPPLLPGDDDMDSPKETLPSK 652
Query: 403 PADHELLRQELNTRFLVQS----AERPGASLGP 431
P E +E TR L+ E PG L P
Sbjct: 653 PVKKE---KEQRTRHLLTDLPLPPELPGGDLSP 682
Score = 33.9 bits (76), Expect = 0.82
Identities = 60/272 (22%), Positives = 98/272 (36%), Gaps = 26/272 (9%)
Query: 781 EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPA-----KEE 835
E++ S SP+ P G S ++ L RS P+ + + R SRSPA
Sbjct: 314 ERSGSYSGRSPS-PYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR---SRSPAYSRHSSSH 369
Query: 836 AAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAW 895
+ K + + HS +P + + G + + + A ++ G+E G+P F
Sbjct: 370 SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMD-GKESKGSPVF-- 426
Query: 896 EPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDR---EPHGYSPERLRGELERARAPH 952
LPR+ + + P ++ + + L E++ +
Sbjct: 427 -------LPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTG 479
Query: 953 LPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPP 1012
+ L+ L A P AL ++ + PPPL T A PP PP
Sbjct: 480 KVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPP-PP 538
Query: 1013 GP---PRSRTTPLGGLGPGEARDYSPSRNPPE 1041
P P +T PL L P A P P +
Sbjct: 539 LPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQ 570
Score = 33.1 bits (74), Expect = 1.4
Identities = 55/233 (23%), Positives = 91/233 (39%), Gaps = 14/233 (6%)
Query: 638 AGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTF-GGLGSLS 696
+G Y QD L PS +H +SN PGS ++ P+ PS + S S
Sbjct: 238 SGASYGQDY--DLSPSR--SHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPS 293
Query: 697 SHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAE 756
++ + S + GS PSP+ R+ F + +S
Sbjct: 294 PYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGR----RRSSSPFLSKRSLSRSPLPS 349
Query: 757 RVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAP 816
R S + + R P + +++ SR S +P P++ L S + A
Sbjct: 350 RKS-MKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAA 408
Query: 817 AEREAEPRVKESR-SPA---KEEAAKMPARASPPHSKAAPGDVKVKEERGEDE 865
A A+ KES+ SP ++E + + A+ S SK P VK+++ + E
Sbjct: 409 AAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTE 461
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 54.3 bits (129), Expect = 6e-07
Identities = 119/510 (23%), Positives = 154/510 (30%), Gaps = 119/510 (23%)
Query: 461 APFPAGLPPTPPAAP--PPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPF 518
AP P+G P+PP P + PKL S + +P P P P PG
Sbjct: 634 APQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPG-- 691
Query: 519 GSLQGAFQPKVSDPYRAVVKVSTCWEGPWQ-----GRTLVPPGRPRGARDSRSLQKTWV- 572
PW G PP PR R S SL +
Sbjct: 692 --------------------------APWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPT 725
Query: 573 -----GVAPAPLSASI-----LSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVG 622
G A P+ +++ L+++PGR V + + P
Sbjct: 726 EGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPS-------VTPTPARGTPRSQSFA 778
Query: 623 AKLDLFGRPPAP-----GVFAGFHYPQDLARPLFPSTGAAHPA----SNPFGPSAHPGSF 673
+ G PP P V P L P GA P S P GPS PG
Sbjct: 779 LRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPP 838
Query: 674 LPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAW 733
P GP +D + PG P GSS GLP E
Sbjct: 839 APAGPASD-----------------------TEEEEPGPEGTPPSRGSSGEGLPFAEEGN 875
Query: 734 NRLHRAPPSFPAPP---PWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRAS 790
+ + P PP P P +D + T R +E + LL +
Sbjct: 876 LTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPG 935
Query: 791 PATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAK---EEAAKMPARASPPH 847
PA P P G PA + P+ + S PA+ A PA P
Sbjct: 936 PAAPLPSPTPG-----------ESPPA--SSLPQPEPSSLPAQGVPTPLAPSPAMQPPVP 982
Query: 848 SKAAPGDVKVKEERGEDEASEPPAG--------GLHPAPLQLGLGRERLGAPGFAWEPFR 899
PG R E +EPPA G AP + + +L G P
Sbjct: 983 PCPGPGLESSAASRWNGE-TEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRL 1041
Query: 900 GLELPRRAFPAAAPAPGSAALLEPPERPYR 929
G PR P P P S + P + R
Sbjct: 1042 G---PR---PVPPPRPESTGTVGPGQAQQR 1065
Score = 52.4 bits (124), Expect = 2e-06
Identities = 124/481 (25%), Positives = 164/481 (34%), Gaps = 79/481 (16%)
Query: 148 PACDGARKVPLQPSK---QMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGY 204
PA G R + Q S+ +++ ++ GG L +R P +S G G+
Sbjct: 575 PATAGPRLLTFQGSELSPELQAAMAGGGPEP------LPLPPARSPSQESIGARSRGSGH 628
Query: 205 SCDSE----SGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAES 260
S + SG D S E+ GT++ P L S GP P V
Sbjct: 629 SQEQPAPQPSGGDP--SPPQERNLPEGTERPPKLCSSLPGQGPPPYVF------------ 674
Query: 261 FLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGA 320
P SP+ +P PGPPPG+ P P P PP P+ R +H + G
Sbjct: 675 MYPQGSPS---SPAPGPPPGA---PWAFSYLAGPPATPPDPPRPKRR----SHSLSRPGP 724
Query: 321 FAGHSQAAANGLHGLSRSSSAPL----GLGKHVSLSPH-GPGPHLSTSHLALRSQAQHQL 375
G ++ A G G + S A L G V SP P P T RSQ+ L
Sbjct: 725 TEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTP----RSQS-FAL 779
Query: 376 HAAMFAAPPTLPPPPALPASSLVLP-GHPADHELLRQELNT----RFLVQSA---ERPGA 427
A PP PPP L + S P P D +E T R L + A E PG
Sbjct: 780 RARRKGPPP--PPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGP 837
Query: 428 SLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFA----------PFPAGLPPTPPAAPPP 477
G E + + + FA P PAG PP PP
Sbjct: 838 PAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPG 897
Query: 478 FD---------KYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPK 528
D K PK +++ F A PG LP P P S + P+
Sbjct: 898 LDFNLTESDTVKRRPKCREREPLQTALLAF-GVASATPGPAAPLPSPTPGESPPASSLPQ 956
Query: 529 VSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKP 588
V T + VPP G S + W G P + + L + P
Sbjct: 957 PEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAA--SRWNGETEPPAAPAALLKVP 1014
Query: 589 G 589
G
Sbjct: 1015 G 1015
Score = 49.3 bits (116), Expect = 2e-05
Identities = 117/441 (26%), Positives = 144/441 (32%), Gaps = 87/441 (19%)
Query: 629 GRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPL----TDPFS 684
G+ P P VF YPQ P P+ G A F A P + P P + S
Sbjct: 666 GQGPPPYVFM---YPQ--GSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLS 720
Query: 685 RPSTFGG--LGSLSSHAFGGLGSHALA---PGGSIFAPKEGS----SVHGLPSPHEAWNR 735
RP G G LGS+A PG S S G P R
Sbjct: 721 RPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALR 780
Query: 736 LHRAPPSFPAPPPWPKSVDAERVSALTNHDREP---DNGKEEQERDLLEKTRLLSR-ASP 791
R P PPP PK R+S+++ EP D +E + R LS A P
Sbjct: 781 ARRKGP----PPPPPK-----RLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGP 831
Query: 792 ATPAGHPVSG--LLLRAQSELGRSGAPAER----EAEPRVKESRSPAKEEAAKMPARASP 845
+ P G P + E G G P R E P +E K+ PA P
Sbjct: 832 SEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPK--PAGPPP 889
Query: 846 PHSKAAPG-DVKVKEE-----RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFR 899
+ PG D + E R + EP L A L G+
Sbjct: 890 RETPVPPGLDFNLTESDTVKRRPKCREREP----LQTALLAFGVASAT------------ 933
Query: 900 GLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPA 959
P A P +P PG + PP EP + + L A +P + P P
Sbjct: 934 ----PGPAAPLPSPTPGES----PPASSLPQPEPSSLPAQGVPTPL--APSPAMQPPVPP 983
Query: 960 LDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRT 1019
G L S S A+ NG PPAA P L+ G T P P
Sbjct: 984 CPGPGLES---------SAASRWNG--ETEPPAA-----PAALLKVPGAGTAPKPVSVAC 1027
Query: 1020 TPLGGLGPGEARDYSPSRNPP 1040
T L GP A P PP
Sbjct: 1028 TQLAFSGPKLAPRLGPRPVPP 1048
Score = 38.9 bits (89), Expect = 0.026
Identities = 96/377 (25%), Positives = 121/377 (32%), Gaps = 87/377 (23%)
Query: 710 PGGSIFAPKEGSSVHGLPSPHEAWNRLHRA-PPSFPAPPPWPKSVDAERVSALTNHDREP 768
P GS +P G P P W + A PP+ P PP PK R +L+ P
Sbjct: 677 PQGSPSSPAPG------PPPGAPWAFSYLAGPPATPPDPPRPK----RRSHSLSRPG--P 724
Query: 769 DNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKES 828
G E E + + L S AT P L+R + P PR S
Sbjct: 725 TEGDAEGEAEGPVGSTL---GSYATLTRRPGRSALVRTSPSV----TPTPARGTPR---S 774
Query: 829 RSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLG--RE 886
+S A K P P + G + EPP P P + G R
Sbjct: 775 QSFALRARRKGPPPPPPKRLSSVSGP-----------SPEPPPLDESPGPKEGATGPRRR 823
Query: 887 RLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREP--HGYSPERL--- 941
L P EP PAP A E P + P G S E L
Sbjct: 824 TLSEPAGPSEP------------PGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFA 871
Query: 942 -RGEL---ERARA----PHLPPAAPALDGALLPSLGALHFPR------LSPAALHNGLLA 987
G L +R + P P P LD L S P+ L A L G+ +
Sbjct: 872 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVAS 931
Query: 988 RTPPAAAALGAPPP---------------LVTAAGPPTPPGPPRSRTTPL-----GGLGP 1027
TP AA L +P P + A G PTP P + P+ GL
Sbjct: 932 ATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLES 991
Query: 1028 GEARDYSPSRNPPEVEA 1044
A ++ PP A
Sbjct: 992 SAASRWNGETEPPAAPA 1008
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,730,852
Number of Sequences: 37866
Number of extensions: 4309577
Number of successful extensions: 48946
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 375
Number of HSP's successfully gapped in prelim test: 1797
Number of HSP's that attempted gapping in prelim test: 24243
Number of HSP's gapped (non-prelim): 19536
length of query: 1045
length of database: 18,247,518
effective HSP length: 113
effective length of query: 932
effective length of database: 13,968,660
effective search space: 13018791120
effective search space used: 13018791120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.