Guide to the Human Genome
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Search of human proteins with 17986005

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17986005 major histocompatibility complex, class II, DR beta
3 precursor [Homo sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17986005 major histocompatibility complex, class II, DR beta ...   544   e-155
gi|239740853 PREDICTED: similar to major histocompatibility comp...   520   e-148
gi|239740855 PREDICTED: similar to major histocompatibility comp...   504   e-143
gi|239740857 PREDICTED: similar to major histocompatibility comp...   502   e-142
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...   495   e-140
gi|239740695 PREDICTED: similar to HLA class II histocompatibili...   495   e-140
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...   491   e-139
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...   491   e-139
gi|239740859 PREDICTED: similar to major histocompatibility comp...   487   e-138
gi|155030211 major histocompatibility complex, class II, DR beta...   484   e-137
gi|18641375 major histocompatibility complex, class II, DR beta ...   470   e-133
gi|52630344 major histocompatibility complex, class II, DR beta ...   460   e-130
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...   441   e-124
gi|239740693 PREDICTED: similar to HLA class II histocompatibili...   441   e-124
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...   424   e-119
gi|239758090 PREDICTED: major histocompatibility complex, class ...   408   e-114
gi|169217452 PREDICTED: similar to HLA class II histocompatibili...   338   4e-93
gi|239758095 PREDICTED: similar to major histocompatibility comp...   328   2e-90
gi|239740749 PREDICTED: similar to major histocompatibility comp...   328   2e-90
gi|239748788 PREDICTED: similar to major histocompatibility comp...   327   9e-90
gi|239740863 PREDICTED: similar to major histocompatibility comp...   326   1e-89
gi|239513955 PREDICTED: similar to major histocompatibility comp...   326   1e-89
gi|169168591 PREDICTED: similar to major histocompatibility comp...   324   4e-89
gi|150418002 major histocompatibility complex, class II, DQ beta...   322   3e-88
gi|239740920 PREDICTED: similar to major histocompatibility comp...   319   2e-87
gi|239740918 PREDICTED: similar to major histocompatibility comp...   319   2e-87
gi|24797076 major histocompatibility complex, class II, DP beta ...   315   3e-86
gi|4504403 major histocompatibility complex, class II, DO beta p...   285   4e-77
gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa...   258   5e-69
gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa...   189   2e-48

>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score =  544 bits (1401), Expect = e-155
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV
Sbjct: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  520 bits (1339), Expect = e-148
 Identities = 254/266 (95%), Positives = 259/266 (97%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLEL KSECHFFNGTERVR+L+R+F
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           HNQEE+ RFDSDVGEYRAV ELGRP AE WNSQKDLLEQKRG+VDNYCRHNYGVGESFTV
Sbjct: 61  HNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEW ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  504 bits (1299), Expect = e-143
 Identities = 250/267 (93%), Positives = 256/267 (95%), Gaps = 1/267 (0%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRF-LELRKSECHFFNGTERVRYLDRY 59
           MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTR +  L L KSECHFFNGTERVR+L+R+
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERH 60

Query: 60  FHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFT 119
           FHNQEE+ RFDSDVGEYRAV ELGRP AE WNSQKDLLEQKRG+VDNYCRHNYGVGESFT
Sbjct: 61  FHNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFT 120

Query: 120 VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 179
           VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN
Sbjct: 121 VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 180

Query: 180 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGL 239
           GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEW ARSESAQSKMLSGVGGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGL 240

Query: 240 LFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           LFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPTGFLS 267


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  502 bits (1292), Expect = e-142
 Identities = 245/266 (92%), Positives = 251/266 (94%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCL+LPGGS +A LTVTLMVLSS LA AGDTRPRFLE   SECHFFNGTERVRYLDRYF
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           HNQEE +RFDSDVGE+RAVTELGRP AE WNSQKDLLEQKRGRVDNYCRHNYGV ESFTV
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  495 bits (1275), Expect = e-140
 Identities = 241/266 (90%), Positives = 253/266 (95%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL   K +CHFFNGTERV++L+R F
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEEF+RFDSDVGEYRAVTELGRPVAESWNSQKD+LE +RG+VD  CRHNYGVGESFTV
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  495 bits (1275), Expect = e-140
 Identities = 241/266 (90%), Positives = 253/266 (95%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL   K +CHFFNGTERV++L+R F
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEEF+RFDSDVGEYRAVTELGRPVAESWNSQKD+LE +RG+VD  CRHNYGVGESFTV
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score =  491 bits (1264), Expect = e-139
 Identities = 240/266 (90%), Positives = 248/266 (93%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCL+LPGGS +A LTVTLMVLSS LA AGDTRPRFLE  K ECHFFNGTERVR L+RYF
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           HNQEE +RFDSDVGE+RAVTELGRP AE WNSQKDLLEQ+R  VD YCRHNYGVGESFTV
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score =  491 bits (1263), Expect = e-139
 Identities = 241/266 (90%), Positives = 249/266 (93%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL+  K ECHFFNGTERVRYL R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGI 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEE +RFDSDVGEYRAVTELGRPVAESWNSQKD LE++R  VD  CRHNYGVGESFTV
Sbjct: 61  YNQEENVRFDSDVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  487 bits (1253), Expect = e-138
 Identities = 241/267 (90%), Positives = 249/267 (93%), Gaps = 1/267 (0%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRF-LELRKSECHFFNGTERVRYLDRY 59
           MVCL+LPGGS +A LTVTLMVLSS LA AGDTR +  L +  SECHFFNGTERVRYLDRY
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRY 60

Query: 60  FHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFT 119
           FHNQEE +RFDSDVGE+RAVTELGRP AE WNSQKDLLEQKRGRVDNYCRHNYGV ESFT
Sbjct: 61  FHNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFT 120

Query: 120 VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 179
           VQRRVHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI N
Sbjct: 121 VQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHN 180

Query: 180 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGL 239
           GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEWRARSESAQSKMLSGVGGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGL 240

Query: 240 LFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           LFLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPRGFLS 267


>gi|155030211 major histocompatibility complex, class II, DR beta 1
           precursor [Homo sapiens]
          Length = 266

 Score =  484 bits (1245), Expect = e-137
 Identities = 237/266 (89%), Positives = 247/266 (92%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS + ALTVTLMVLSS LA +GDTRPRFL   K ECHFFNGTERVR+LDRYF
Sbjct: 1   MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEE +RFDSDVGE+RAVTELGRP AE WNSQKD+LEQ R  VD YCRHNYGV ESFTV
Sbjct: 61  YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWF NGQEEKAG+VSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score =  470 bits (1210), Expect = e-133
 Identities = 231/266 (86%), Positives = 242/266 (90%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +A LTVTLMVLSS LA AGDTRPRFL+  K ECHFFNGTERVR+L R  
Sbjct: 1   MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEE LRFDSDVGEYRAVTELGRP AE WNSQKD LE +R  VD YCRHNYGVGESFTV
Sbjct: 61  YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYPA+TQ LQHHNLLVCSV+GFYPGSIEVRWFRN QEEKAGVVSTGLIQNG
Sbjct: 121 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEWRA+SESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLGAGLFIYF+NQKGHSGL PTG +S
Sbjct: 241 FLGAGLFIYFKNQKGHSGLHPTGLVS 266


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score =  460 bits (1184), Expect = e-130
 Identities = 225/266 (84%), Positives = 241/266 (90%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTL VLSS LA AGDT+PRFLE  K ECHF NGTERV  L RY 
Sbjct: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEE+ R++SD+GEY+AVTELGRP AE WNSQKDLLE++R  VD YCR+NYGV ESFTV
Sbjct: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ S LTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  441 bits (1134), Expect = e-124
 Identities = 212/232 (91%), Positives = 222/232 (95%)

Query: 35  RFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQK 94
           RFL   K +CHFFNGTERV++L+R F+NQEEF+RFDSDVGEYRAVTELGRPVAESWNSQK
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPG 154
           D+LE +RG+VD  CRHNYGVGESFTVQRRVHP+VTVYPAKTQPLQHHNLLVCSVSGFYPG
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 152

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSV S LT
Sbjct: 153 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 212

Query: 215 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 213 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  441 bits (1134), Expect = e-124
 Identities = 212/232 (91%), Positives = 222/232 (95%)

Query: 35  RFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQK 94
           RFL   K +CHFFNGTERV++L+R F+NQEEF+RFDSDVGEYRAVTELGRPVAESWNSQK
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPG 154
           D+LE +RG+VD  CRHNYGVGESFTVQRRVHP+VTVYPAKTQPLQHHNLLVCSVSGFYPG
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 152

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSV S LT
Sbjct: 153 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 212

Query: 215 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 213 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score =  424 bits (1089), Expect = e-119
 Identities = 219/268 (81%), Positives = 231/268 (86%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL   K +CHFFNGTERV++L+R F
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEEF+RFDSDVGEYRAVTELGRPVAE    Q DLL          C     + +SF +
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105

Query: 121 Q--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178
                VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165

Query: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLG 238
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225

Query: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score =  408 bits (1049), Expect = e-114
 Identities = 197/232 (84%), Positives = 211/232 (90%)

Query: 35  RFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQK 94
           RFLE  K ECHF NGTERV  L RY +NQEE+ R++SD+GEY+AVTELGRP AE WNSQK
Sbjct: 47  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 106

Query: 95  DLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPG 154
           DLLE++R  VD YCR+NYGV ESFTVQRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPG
Sbjct: 107 DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 166

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+ S LT
Sbjct: 167 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 226

Query: 215 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 266
           V+W ARSESAQSKMLSGVGGFVLGLLFLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 227 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 278


>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-4 beta chain, partial [Homo sapiens]
          Length = 223

 Score =  338 bits (866), Expect = 4e-93
 Identities = 159/177 (89%), Positives = 168/177 (94%)

Query: 35  RFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQK 94
           RFLE  K ECHFFNGTERVR+LDRYF++QEE++RFDSDVGEYRAVTELGRP AE WNSQK
Sbjct: 47  RFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQK 106

Query: 95  DLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPG 154
           DLLEQKR  VD YCRHNYGVGESFTVQRRV+P+VTVYPAKTQPLQHHNLLVCSV+GFYPG
Sbjct: 107 DLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPG 166

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTS 211
           SIEVRWFRNGQEEK GVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+TS
Sbjct: 167 SIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  328 bits (842), Expect = 2e-90
 Identities = 160/252 (63%), Positives = 195/252 (77%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG   A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + R  +N+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE +RFDSDVGE+RAVT LG P AE WNSQKD+LE+KR  VD  CRHNY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  328 bits (842), Expect = 2e-90
 Identities = 160/252 (63%), Positives = 195/252 (77%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG   A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + R  +N+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE +RFDSDVGE+RAVT LG P AE WNSQKD+LE+KR  VD  CRHNY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239748788 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 2 [Homo sapiens]
          Length = 281

 Score =  327 bits (837), Expect = 9e-90
 Identities = 159/252 (63%), Positives = 195/252 (77%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG  +A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + R  +N+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE +RFDSDVGE+RAVT LG P AE WNSQKD+LE+KR  VD  CRHNY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740863 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  326 bits (835), Expect = 1e-89
 Identities = 159/252 (63%), Positives = 194/252 (76%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG   A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + R  +N+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE +RFDSDVGE+RAVT LG P AE WNSQKD+LE+KR  VD  CRHNY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239513955 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  326 bits (835), Expect = 1e-89
 Identities = 159/252 (63%), Positives = 194/252 (76%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG   A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + R  +N+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE +RFDSDVGE+RAVT LG P AE WNSQKD+LE+KR  VD  CRHNY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score =  324 bits (831), Expect = 4e-89
 Identities = 158/252 (62%), Positives = 194/252 (76%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG  +A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + RY +N+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE+ RFDSDVG YRAVT LG P AE WNSQK++LE+ R  VD  CRHNY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|150418002 major histocompatibility complex, class II, DQ beta 1
           precursor [Homo sapiens]
          Length = 261

 Score =  322 bits (824), Expect = 3e-88
 Identities = 160/252 (63%), Positives = 191/252 (75%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PG   +A +T+ L +LSS LA   D+   F+   K  C+F NGTERVR + RY +N+
Sbjct: 7   LRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE+ RFDSDVG YRAVT  GRP AE WNSQK++LE  R  +D  CRHNY V     +QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYPG I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ S +TVEWRA+SESAQSKMLSGVGGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I  R+QKG
Sbjct: 247 LGLIIRQRSQKG 258


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score =  319 bits (817), Expect = 2e-87
 Identities = 154/252 (61%), Positives = 192/252 (76%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG  +A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + RY +N+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE+ RFDSDVG YRAVT LG P AE WNSQK++LE+ R  +D  CRHNY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ + + VEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score =  319 bits (817), Expect = 2e-87
 Identities = 154/252 (61%), Positives = 192/252 (76%)

Query: 4   LKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQ 63
           L++PGG  +A +T+ L +LS+ +A   D+   F+   K  C+F NGTERVR + RY +N+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRR 123
           EE+ RFDSDVG YRAVT LG P AE WNSQK++LE+ R  +D  CRHNY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ + + VEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 AGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score =  315 bits (807), Expect = 3e-86
 Identities = 154/258 (59%), Positives = 192/258 (74%), Gaps = 2/258 (0%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           M+ L++       ALT  LMVL + +     T   +L   + EC+ FNGT+R  +L+RY 
Sbjct: 1   MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +N+EEF RFDSDVGE+RAVTELGRP AE WNSQKD+LE+KR   D  CRHNY +G   T+
Sbjct: 59  YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118

Query: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+V V P+K  PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
           DWTFQ LVMLE  P+ G+VYTCQVEH S+ S +TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238

Query: 241 FLGAGLFIYFRNQKGHSG 258
             G G+F++ R++K   G
Sbjct: 239 ICGVGIFMHRRSKKVQRG 256


>gi|4504403 major histocompatibility complex, class II, DO beta
           precursor [Homo sapiens]
          Length = 273

 Score =  285 bits (728), Expect = 4e-77
 Identities = 138/252 (54%), Positives = 182/252 (72%)

Query: 12  LAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDS 71
           + AL V L  L S +    D+   F+   K++C+F NGTE+V+++ R+  N EE++RFDS
Sbjct: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68

Query: 72  DVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVY 131
           DVG + A+T+LG+P AE WNS+ DLLE+ R  VD  CRHNY +G  FTV R+V P+VTVY
Sbjct: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128

Query: 132 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188

Query: 192 TVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 251
             P  G VYTC V+H S+ S ++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248

Query: 252 NQKGHSGLQPTG 263
            QKG+   Q +G
Sbjct: 249 AQKGYVRTQMSG 260


>gi|169168671 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 241

 Score =  258 bits (658), Expect = 5e-69
 Identities = 124/140 (88%), Positives = 130/140 (92%)

Query: 124 VHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           + P+ T+YPAKT+PL H N LVCSVSGFYPGSIEVRWF+NGQEEKA VVS GLIQNGDWT
Sbjct: 99  LQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDWT 158

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLG 243
           FQTLVMLETVPRSGEVYTCQVEHPSVTS LTVEW AR+ESAQSKMLSGVGGFVLGLLFLG
Sbjct: 159 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFLG 218

Query: 244 AGLFIYFRNQKGHSGLQPTG 263
            GLFIYFRNQKGHSGLQPTG
Sbjct: 219 TGLFIYFRNQKGHSGLQPTG 238


>gi|169168589 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 140

 Score =  189 bits (481), Expect = 2e-48
 Identities = 93/123 (75%), Positives = 104/123 (84%)

Query: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
           MVCLKLPGGS +AALTVTL VLSS LA AGDT+PRFLE  K ECHF NGTERV  L RY 
Sbjct: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
           +NQEE+ R++SD+GEY+AVTELGRP AE WNSQKDLLE++R  VD YCR+NYGV ESFTV
Sbjct: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120

Query: 121 QRR 123
           QRR
Sbjct: 121 QRR 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,307,733
Number of Sequences: 37866
Number of extensions: 433387
Number of successful extensions: 1186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1019
Number of HSP's gapped (non-prelim): 169
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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