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Search of human proteins with 148747351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148747351 protein kinase C and casein kinase substrate in neu... 994 0.0
gi|24308229 protein kinase C and casein kinase substrate in neur... 632 0.0
gi|19224660 protein kinase C and casein kinase substrate in neur... 493 e-139
gi|165905601 proline-serine-threonine phosphatase interacting pr... 69 1e-11
gi|20149528 proline-serine-threonine phosphatase interacting pro... 69 1e-11
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 63 5e-10
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 63 7e-10
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 60 6e-09
gi|27544941 myosin IF [Homo sapiens] 59 8e-09
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 58 2e-08
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 58 2e-08
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 58 2e-08
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 58 2e-08
gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 55 1e-07
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 55 1e-07
gi|208022687 GTPase regulator associated with the focal adhesion... 55 1e-07
gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 54 3e-07
gi|115527120 nebulin [Homo sapiens] 54 3e-07
gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 53 5e-07
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 53 7e-07
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 53 7e-07
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 53 7e-07
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 53 7e-07
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 53 7e-07
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 53 7e-07
gi|171906575 drebrin-like isoform c [Homo sapiens] 53 7e-07
gi|62198235 drebrin-like isoform b [Homo sapiens] 53 7e-07
gi|21361670 drebrin-like isoform a [Homo sapiens] 53 7e-07
gi|23308553 spermatogenesis associated 13 [Homo sapiens] 52 2e-06
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 52 2e-06
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 994 bits (2570), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 60
MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT
Sbjct: 1 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 60
Query: 61 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 120
EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF
Sbjct: 61 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 120
Query: 121 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 180
HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP
Sbjct: 121 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 180
Query: 181 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 240
SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR
Sbjct: 181 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 240
Query: 241 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 300
LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ
Sbjct: 241 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 300
Query: 301 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS 360
FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS
Sbjct: 301 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS 360
Query: 361 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD 420
YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD
Sbjct: 361 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD 420
Query: 421 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN 480
DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN
Sbjct: 421 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN 480
Query: 481 YVEAIQ 486
YVEAIQ
Sbjct: 481 YVEAIQ 486
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 632 bits (1631), Expect = 0.0
Identities = 311/487 (63%), Positives = 383/487 (78%), Gaps = 45/487 (9%)
Query: 1 MSVTYDD-SVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQL 59
MS +YD+ S+ E ++DSFWEVGNYKRTVKRIDDGHRLC+DLMNC+ ERA+IEKAY QQL
Sbjct: 1 MSSSYDEASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQL 60
Query: 60 TEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEA 119
T+WA+RWRQL+EKGPQYG++E+AW A M+EA++VSELH EVK +L+N+D EK+KNWQK+A
Sbjct: 61 TDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDA 120
Query: 120 FHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAD 179
+HKQ+MGGFKETKEAEDGFRKAQKPWAKK+KE+EAAKKA+H ACKEEKLA++RE NSK +
Sbjct: 121 YHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTE 180
Query: 180 PSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEK 239
S+ PEQ KKLQDK++KCKQDV KT+EKYEK L+++ + TPQYMENMEQVFEQCQQFEEK
Sbjct: 181 QSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEK 240
Query: 240 RLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWP 299
RL F +EVLL++++HL+L+ + Y +Y +LEQ+IR ADA EDLRWFR+ GPGM MNWP
Sbjct: 241 RLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWP 300
Query: 300 QFEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 358
QFEEW+ DL T +++EK+ K +GV LT N TG A + SQ
Sbjct: 301 QFEEWNPDLPHTTTKKEKQPKKAEGVALT--NATG------------------AVESTSQ 340
Query: 359 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 418
+ D GS VSSY++ Q Y T+WSDDES NPF ++ NG +NP
Sbjct: 341 AG--------DRGS------------VSSYDRGQPYATEWSDDESGNPFGGSETNGGANP 380
Query: 419 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 478
F+DD+ VRVRALYDY+GQE DELSFKAGDELTK+ +EDEQGWC+GRLD+GQ+GLYP
Sbjct: 381 FEDDSKG---VRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYP 437
Query: 479 ANYVEAI 485
ANYVEAI
Sbjct: 438 ANYVEAI 444
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 493 bits (1270), Expect = e-139
Identities = 244/481 (50%), Positives = 323/481 (67%), Gaps = 63/481 (13%)
Query: 6 DDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARR 65
++ G E SFWE GNY+RTV+R++DGHRLC DL++C ERARIEKAYAQQL +WAR+
Sbjct: 4 EEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARK 63
Query: 66 WRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMM 125
WR VEKGPQYGT+EKAW AF + AER+S LHLEV+ L D E+++ WQ+ AFH+ ++
Sbjct: 64 WRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHRPVL 123
Query: 126 GGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPE 185
GGF+E++ AEDGFRKAQKPW K+LKEVEA+KK++HAA K+EK A +RE+++KAD +++ E
Sbjct: 124 GGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQE 183
Query: 186 QLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFR 245
QL+KLQ+++E+C ++ KTK +YE++L EL + TP+YME+MEQ FE CQ E +RL FF+
Sbjct: 184 QLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLLFFK 243
Query: 246 EVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEEWS 305
++LL + +HLDLS+ + ++ DL Q I AA EDLRW+R+ HGPGMAMNWPQFEEWS
Sbjct: 244 DMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWS 303
Query: 306 ADLNRTLSRREK-KKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSSYNPF 364
D RT+SR+EK ++ D VTLT I T D + P P +P Q
Sbjct: 304 LDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP--------PQSPGSPGTGQDE---- 351
Query: 365 EDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDAT 424
+WSD+ES
Sbjct: 352 --------------------------------EWSDEES------------------PRK 361
Query: 425 SGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEA 484
+ T VRVRALYDY GQE DELSF+AG+EL KM +EDEQGWC+G+L +G++GLYPANYVE
Sbjct: 362 AATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVEC 421
Query: 485 I 485
+
Sbjct: 422 V 422
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 68.9 bits (167), Expect = 1e-11
Identities = 67/280 (23%), Positives = 124/280 (44%), Gaps = 30/280 (10%)
Query: 14 SSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKG 73
S+D +G Y ++ +++G + C + + L ERA IE+ Y + L +R K
Sbjct: 12 SADILSTIG-YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSR-------KK 63
Query: 74 P----QYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFK 129
P + T+++A F + + V++ H+++ SL ++ K+ E F ++ K
Sbjct: 64 PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSL-REEARKM-----EEFREKQKLQRK 117
Query: 130 ETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACK---EEKLAISREANSKADPSLNPEQ 186
+T+ D K + KK + AKK + C+ E + A+SR AN +NP+Q
Sbjct: 118 KTELIMDAIHKQKSLQFKKTMD---AKKNYEQKCRDKDEAEQAVSRSAN-----LVNPKQ 169
Query: 187 LKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFRE 246
+KL K+ K V + + Y + LD+ ++ + E + E +R+ FFR
Sbjct: 170 QEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRN 229
Query: 247 VLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWF 286
L L V +Y + +S+ D+ +F
Sbjct: 230 ALWLHVNQLSQQCVTS-DEMYEQVRKSLEMCSIQRDIEYF 268
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/278 (20%), Positives = 119/278 (42%), Gaps = 25/278 (8%)
Query: 16 DSFW-----EVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLV 70
D+FW Y+ ++R+ DG ++C D+ L +RA+ E+ Y ++L + AR+
Sbjct: 9 DAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQT 68
Query: 71 EKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMND--DFEKIKNWQKEAFHKQMMGGF 128
E ++ ++ + + E V H+++ +L + E+ + QKE
Sbjct: 69 E----INSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKE---------- 114
Query: 129 KETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLK 188
+ K+ E + QK K+ +KK + C++ A +A + + + +Q++
Sbjct: 115 -QRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDA--EQAFERISANGHQKQVE 171
Query: 189 KLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL 248
K Q+K +CK + + Y +S+ +L++ ++ + E Q E RL R L
Sbjct: 172 KSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNAL 231
Query: 249 LEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWF 286
L + V +Y ++ ++ D+ F
Sbjct: 232 WVHSNQLSMQCVKD-DELYEEVRLTLEGCSIDADIDSF 268
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 63.2 bits (152), Expect = 5e-10
Identities = 46/154 (29%), Positives = 72/154 (46%), Gaps = 13/154 (8%)
Query: 336 SLPSKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYP 395
+LP + L V P A+ + P + ++ V E D +E+
Sbjct: 343 ALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYEDVEEMD--------RHEQEDEPE 394
Query: 396 TDWSD--DESNNPFSSTDANGDSNPFDDDATS-GTEVRVRALYDYEGQEHDELSFKAGDE 452
D+ + + ++ FSS A P A + + ALYDY+G+ DELSF D
Sbjct: 395 GDYEEVLEPEDSSFSSALAGSSGCPAGAGAGAVALGISAVALYDYQGEGSDELSFDPDDV 454
Query: 453 LTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
+T +E DE GW +GR +G GL+PANYV+ ++
Sbjct: 455 ITDIEMVDE-GWWRGRC-HGHFGLFPANYVKLLE 486
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 62.8 bits (151), Expect = 7e-10
Identities = 82/384 (21%), Positives = 159/384 (41%), Gaps = 54/384 (14%)
Query: 16 DSFWEVGN--YKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKG 73
++FW N + + G +L + + ERA IE+AY++ +T+ A+
Sbjct: 8 ENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKS----ASNY 63
Query: 74 PQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE 133
Q GT W F + E+++ HL++ L E IK QK + ++ + K+TKE
Sbjct: 64 SQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQ----ELIKEVQK--YGEEQVKSHKKTKE 117
Query: 134 AEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKK---L 190
G +A + + ++ +K+ ++A C E+ E+LKK
Sbjct: 118 EVAGTLEAVQTIQSITQALQKSKENYNAKCVEQ------------------ERLKKEGAT 159
Query: 191 QDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLE 250
Q +IEK K + Y+ +++ + + M + ++ Q EE L +E++
Sbjct: 160 QREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGS 219
Query: 251 VQK-----HLDLSNVAGYKAIYHDLEQSIRAADAVEDL-RWFRANHGPGMAM-NWPQFEE 303
+ HL + V H+ + A VE L + F + G G +FEE
Sbjct: 220 LSNAIKEIHLQIGQV-------HEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEE 272
Query: 304 --WSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVP--SNPAQSAQSQS 359
++ + R+ K A G+ + +S+ + +LN+P S + ++
Sbjct: 273 CDTASAVEGIKPRKRKTFALPGIIK---KEKDAESVECPDADSLNIPDVDEEGYSIKPET 329
Query: 360 SYNPFEDEDDTGSTVSEKDDTKAK 383
+ N ++ S+ S+ +D + K
Sbjct: 330 NQNDTKENHFYSSSDSDSEDEEPK 353
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 59.7 bits (143), Expect = 6e-09
Identities = 60/254 (23%), Positives = 113/254 (44%), Gaps = 16/254 (6%)
Query: 16 DSFWEVGN--YKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKG 73
++FW N + + G +L + + ERA IE+AY++ +T+ A+
Sbjct: 8 ENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKS----ASNY 63
Query: 74 PQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE 133
Q GT W F + E+++ HL++ L E IK QK + ++ + K+TKE
Sbjct: 64 SQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQ----ELIKEVQK--YGEEQVKSHKKTKE 117
Query: 134 AEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDK 193
G +A + + ++ +K+ ++A C E++ + +E ++ + + KK D
Sbjct: 118 EVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE-RLKKEGATQREIEKAAVKSKKATDT 176
Query: 194 IEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQ--VFEQCQQF-EEKRLRFFREVLLE 250
+ + K +E+ + E Q +++ NM V Q+F E K R L+E
Sbjct: 177 YKLYVEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIE 236
Query: 251 VQKHLDLSNVAGYK 264
++ S V G K
Sbjct: 237 FEECDTASAVEGIK 250
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 59.3 bits (142), Expect = 8e-09
Identities = 32/56 (57%), Positives = 39/56 (69%), Gaps = 2/56 (3%)
Query: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
R RALY Y GQ+ DELSF +E+ ++ ED GW KGRL +GQ GL+P NYVE I
Sbjct: 1045 RCRALYQYVGQDVDELSFNV-NEVIEILMEDPSGWWKGRL-HGQEGLFPGNYVEKI 1098
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 58.2 bits (139), Expect = 2e-08
Identities = 81/340 (23%), Positives = 137/340 (40%), Gaps = 48/340 (14%)
Query: 170 ISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQV 229
+ E + + SLN E +K ++ + ++++ ++ L +L+ E
Sbjct: 312 LESETGTTEEHSLNKEA-RKWATRVAREHKNIVHQ----QRVLNDLECHGAAVSEQSRAE 366
Query: 230 FEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRAN 289
EQ + +R + L+ + LDL G + + +E+ RW R
Sbjct: 367 LEQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARP- 425
Query: 290 HGPGMAMNWPQFEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPS 349
P + N LN R E ++ D + + D S S PS TL
Sbjct: 426 --PAVTSNGTLHS-----LNADTEREEGEEFEDNMDVFD-----DSS--SSPSGTLRNYP 471
Query: 350 NPAQSAQSQSSYNPFE---DEDDTGSTVSE---KDDTKAKNVSSY-----EKTQSYPTDW 398
+ S + P E +E + + + +D KA+N EK +PT
Sbjct: 472 LTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQFPTSN 531
Query: 399 S-----------DDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSF 447
S D S+ +ST+A S + DA+ V+ALYDYEGQ DELSF
Sbjct: 532 SLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGDASV---CFVKALYDYEGQTDDELSF 588
Query: 448 KAGD--ELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
G + E++D+ G+ +G NG++G++P+ VE +
Sbjct: 589 PEGAIIRILNKENQDDDGFWEGEF-NGRIGVFPSVLVEEL 627
Score = 29.6 bits (65), Expect = 6.4
Identities = 37/202 (18%), Positives = 78/202 (38%), Gaps = 23/202 (11%)
Query: 37 LCSDLMNCLHERARIEKAYAQQLTEWA-----RRWRQL-VEKGPQYGTVEKAWMAFMSEA 90
L D+ ++A IE+ YAQ + + A R W + + Y ++ W +F+
Sbjct: 35 LLEDMRTFSQKKAAIEREYAQGMQKLASQYLKRDWPGVKADDRNDYRSMYPVWKSFLEGT 94
Query: 91 ERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLK 150
+V++ + + E KN+ E ++ K D K Q + +K
Sbjct: 95 MQVAQSRMNI--------CENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVK 146
Query: 151 EVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLK--------KLQDKIEKCKQDVL 202
++ KK + ++ A+ +A+ +A L+ Q + KL+ + +C
Sbjct: 147 DLAKGKKKYFET-EQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNSKAT 205
Query: 203 KTKEKYEKSLKELDQGTPQYME 224
+ Y +L + +Y +
Sbjct: 206 HARNDYLLTLAAANAHQDRYYQ 227
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/57 (45%), Positives = 40/57 (70%), Gaps = 2/57 (3%)
Query: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
+ +ALYD+ G+ DELSFKAGD +T++E D+ W G L G+ G++P NY++ +Q
Sbjct: 675 KAKALYDFRGENEDELSFKAGDIITELESVDDD-WMSGEL-MGKSGIFPKNYIQFLQ 729
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 11/102 (10%)
Query: 390 KTQSYPTDWSDDESNNPFSSTDANGDSNPFD---DDATSGTEVR------VRALYDYEGQ 440
+T +P ++ + + P S + P +D+ S ++V AL+ + +
Sbjct: 557 RTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAE 616
Query: 441 EHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYV 482
D+LSFK GD + +E D WC+GRL + + G++PA +V
Sbjct: 617 TSDDLSFKRGDRIQILERLDSD-WCRGRLQDRE-GIFPAVFV 656
Score = 43.1 bits (100), Expect = 6e-04
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 23/165 (13%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYN------PFEDEDDTGST------VSEKDDTK 381
D+ L S+P N PS+ + S + + P E DD T + EK DT
Sbjct: 417 DEHLRSRP----NDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTD 472
Query: 382 AKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQE 441
+ + +P ++ + P NG G+ R A ++Y G++
Sbjct: 473 WYRGNCRNQIGIFPANYVKVIIDIP---EGGNGKRECVSSHCVKGS--RCVARFEYIGEQ 527
Query: 442 HDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
DELSF G+ + E +E+ W +G + G+ G++P N+VE ++
Sbjct: 528 KDELSFSEGEIIILKEYVNEE-WARGEV-RGRTGIFPLNFVEPVE 570
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/57 (45%), Positives = 40/57 (70%), Gaps = 2/57 (3%)
Query: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
+ +ALYD+ G+ DELSFKAGD +T++E D+ W G L G+ G++P NY++ +Q
Sbjct: 711 KAKALYDFRGENEDELSFKAGDIITELESVDDD-WMSGEL-MGKSGIFPKNYIQFLQ 765
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 11/102 (10%)
Query: 390 KTQSYPTDWSDDESNNPFSSTDANGDSNPFD---DDATSGTEVR------VRALYDYEGQ 440
+T +P ++ + + P S + P +D+ S ++V AL+ + +
Sbjct: 593 RTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAE 652
Query: 441 EHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYV 482
D+LSFK GD + +E D WC+GRL + + G++PA +V
Sbjct: 653 TSDDLSFKRGDRIQILERLDSD-WCRGRLQDRE-GIFPAVFV 692
Score = 43.1 bits (100), Expect = 6e-04
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 23/165 (13%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYN------PFEDEDDTGST------VSEKDDTK 381
D+ L S+P N PS+ + S + + P E DD T + EK DT
Sbjct: 453 DEHLRSRP----NDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTD 508
Query: 382 AKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQE 441
+ + +P ++ + P NG G+ R A ++Y G++
Sbjct: 509 WYRGNCRNQIGIFPANYVKVIIDIP---EGGNGKRECVSSHCVKGS--RCVARFEYIGEQ 563
Query: 442 HDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
DELSF G+ + E +E+ W +G + G+ G++P N+VE ++
Sbjct: 564 KDELSFSEGEIIILKEYVNEE-WARGEV-RGRTGIFPLNFVEPVE 606
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/57 (45%), Positives = 40/57 (70%), Gaps = 2/57 (3%)
Query: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
+ +ALYD+ G+ DELSFKAGD +T++E D+ W G L G+ G++P NY++ +Q
Sbjct: 734 KAKALYDFRGENEDELSFKAGDIITELESVDDD-WMSGEL-MGKSGIFPKNYIQFLQ 788
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 11/102 (10%)
Query: 390 KTQSYPTDWSDDESNNPFSSTDANGDSNPFD---DDATSGTEVR------VRALYDYEGQ 440
+T +P ++ + + P S + P +D+ S ++V AL+ + +
Sbjct: 616 RTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAE 675
Query: 441 EHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYV 482
D+LSFK GD + +E D WC+GRL + + G++PA +V
Sbjct: 676 TSDDLSFKRGDRIQILERLDSD-WCRGRLQDRE-GIFPAVFV 715
Score = 43.1 bits (100), Expect = 6e-04
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 23/165 (13%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYN------PFEDEDDTGST------VSEKDDTK 381
D+ L S+P N PS+ + S + + P E DD T + EK DT
Sbjct: 476 DEHLRSRP----NDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTD 531
Query: 382 AKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQE 441
+ + +P ++ + P NG G+ R A ++Y G++
Sbjct: 532 WYRGNCRNQIGIFPANYVKVIIDIP---EGGNGKRECVSSHCVKGS--RCVARFEYIGEQ 586
Query: 442 HDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
DELSF G+ + E +E+ W +G + G+ G++P N+VE ++
Sbjct: 587 KDELSFSEGEIIILKEYVNEE-WARGEV-RGRTGIFPLNFVEPVE 629
>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
Length = 261
Score = 55.5 bits (132), Expect = 1e-07
Identities = 28/64 (43%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Query: 423 ATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLD-NGQVGLYPANY 481
A G R RA+YDY + DE+SF+ GD + ++ D+ GW G ++ G G+ PANY
Sbjct: 199 APGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDD-GWMYGTVERTGDTGMLPANY 257
Query: 482 VEAI 485
VEAI
Sbjct: 258 VEAI 261
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 55.5 bits (132), Expect = 1e-07
Identities = 26/55 (47%), Positives = 39/55 (70%), Gaps = 2/55 (3%)
Query: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEA 484
+VRA+YD+E E +EL+FKAG+ +T ++D D W KG G +GL+P+N+V A
Sbjct: 214 KVRAIYDFEAAEDNELTFKAGEIITVLDDSD-PNWWKGETHQG-IGLFPSNFVTA 266
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 55.5 bits (132), Expect = 1e-07
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 6/142 (4%)
Query: 342 SSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDD 401
SS +V SNP S SS P + D V + + + + P+
Sbjct: 622 SSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFS 681
Query: 402 ESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
++P ++ + DS+P S + +ALY + + ELSF AG + E
Sbjct: 682 APSSPMPTSSTSSDSSP-----VSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQE 736
Query: 462 QGWCKGRLDNGQVGLYPANYVE 483
GW +G L NG+ GL P NYVE
Sbjct: 737 PGWLEGTL-NGKTGLIPENYVE 757
>gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo
sapiens]
Length = 342
Score = 53.9 bits (128), Expect = 3e-07
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 13/144 (9%)
Query: 351 PAQSAQSQSSYNPFEDE-DDTGSTVSEKDDTKAKNVSSYE----KTQSYPTDWSDDESNN 405
PAQ+ + F ++ ++ G ++ + + + SS + K S P S N
Sbjct: 197 PAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLN 256
Query: 406 PFSSTDAN------GDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDE 459
S ++ N G S+ + + V ALY +EGQ+ +L+F+AGD +T +
Sbjct: 257 SGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKT 316
Query: 460 DEQ-GWCKGRLDNGQVGLYPANYV 482
D W +G+L GQ G++PANYV
Sbjct: 317 DSHFDWWEGKL-RGQTGIFPANYV 339
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 53.9 bits (128), Expect = 3e-07
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 339 SKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDW 398
S+ +S L++ +S S++ D ST S+ + KT P
Sbjct: 6538 SRSASALSISGGEEKSEHSEAP-------DHHLSTYSDGGVFAVSTAYKHAKTTELPQQR 6590
Query: 399 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 458
S + +T ++ S+P +T+G R A+YDY + DE+SFK GD + ++
Sbjct: 6591 SSSVATQ--QTTVSSIPSHP----STAGKIFR--AMYDYMAADADEVSFKDGDAIINVQA 6642
Query: 459 EDEQGWCKGRLD-NGQVGLYPANYVEAI 485
DE GW G + G+ G+ PANYVEAI
Sbjct: 6643 IDE-GWMYGTVQRTGRTGMLPANYVEAI 6669
Score = 35.8 bits (81), Expect = 0.090
Identities = 55/211 (26%), Positives = 89/211 (42%), Gaps = 23/211 (10%)
Query: 90 AERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE--AEDGFRKAQKPWAK 147
A++ ++L +VK N D EK K + Q+ K+ +E ++ K K
Sbjct: 5783 AKKAAKLSSQVKYR-ENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHK 5841
Query: 148 KLKEVEAAKKAHHAACKEEKLAISREANSKADPSLN-----PEQLKKLQDKIEKCKQDVL 202
+ +++ + +H +LA S + K + S P+ L++L K Q ++
Sbjct: 5842 PVTDMKESLIMNHVL-NTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIV 5900
Query: 203 KTKEKYEKSLKE--LDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL------LEVQKH 254
K KEKYEK + LD TP Y+ E +Q Q +E R + + LEV
Sbjct: 5901 KYKEKYEKERGKPMLDFETPTYITAKES--QQMQSGKEYRKDYEESIKGRNLTGLEVTPA 5958
Query: 255 L----DLSNVAGYKAIYHDLEQSIRAADAVE 281
L + +A K DLE+SIR E
Sbjct: 5959 LLHVKYATKIASEKEYRKDLEESIRGKGLTE 5989
>gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo
sapiens]
Length = 323
Score = 53.1 bits (126), Expect = 5e-07
Identities = 25/55 (45%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 429 VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQ-GWCKGRLDNGQVGLYPANYV 482
+ V ALY +EGQ+ +L+F+AGD +T + D W +G+L GQ G++PANYV
Sbjct: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKL-RGQTGIFPANYV 320
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 156 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 214
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 215 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 274
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 275 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 312
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 409 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 468
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 469 -GWFVGTSRRTKFFGTFPGNYVKRL 492
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 488 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 546
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 547 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 606
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 607 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 644
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 741 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 800
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 801 -GWFVGTSRRTKFFGTFPGNYVKRL 824
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 325 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 383
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 384 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 443
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 444 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 481
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 578 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 637
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 638 -GWFVGTSRRTKFFGTFPGNYVKRL 661
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 395 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 453
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 454 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 513
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 514 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 551
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 648 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 707
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 708 -GWFVGTSRRTKFFGTFPGNYVKRL 731
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 308 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 366
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 367 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 426
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 427 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 464
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 561 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 620
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 621 -GWFVGTSRRTKFFGTFPGNYVKRL 644
>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
sapiens]
Length = 666
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Query: 334 DQSLPSKPSSTLNVPSNPAQSAQSQSSYNP---FEDEDDTGSTVSEKDDTKAKNVSSYEK 390
D+SL +P S+ ++ S+ + +S+ + P D+ + ++ D + +
Sbjct: 330 DRSL-ERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSF 388
Query: 391 TQSYPTDWS---DDESNNPFSSTDAN-GDSNPFDDDATSGTE-VRVRALYDYEGQEHDEL 445
T S P+ S D ES +SST + G S P + T E + +A+YD++ Q EL
Sbjct: 389 TSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKEL 448
Query: 446 SFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
SFK GD + + D Q W +G +G+VG++P +YVE +
Sbjct: 449 SFKKGDTVYILRKID-QNWYEGE-HHGRVGIFPISYVEKL 486
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 403 SNNPFSSTDANGDSNP-FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDE 461
S++ S +N P F + G +ALY+Y + DEL + D + ME D+
Sbjct: 583 SSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDD 642
Query: 462 QGWCKGRLDNGQ-VGLYPANYVEAI 485
GW G + G +P NYV+ +
Sbjct: 643 -GWFVGTSRRTKFFGTFPGNYVKRL 666
>gi|171906575 drebrin-like isoform c [Homo sapiens]
Length = 439
Score = 52.8 bits (125), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 425 SGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEA 484
SG + RALYDY+ + E+SF + +T +E DE GW +G +G G++PANYVE
Sbjct: 379 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDE-GWWRGYGPDGHFGMFPANYVEL 437
Query: 485 IQ 486
I+
Sbjct: 438 IE 439
>gi|62198235 drebrin-like isoform b [Homo sapiens]
Length = 430
Score = 52.8 bits (125), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 425 SGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEA 484
SG + RALYDY+ + E+SF + +T +E DE GW +G +G G++PANYVE
Sbjct: 370 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDE-GWWRGYGPDGHFGMFPANYVEL 428
Query: 485 IQ 486
I+
Sbjct: 429 IE 430
>gi|21361670 drebrin-like isoform a [Homo sapiens]
Length = 431
Score = 52.8 bits (125), Expect = 7e-07
Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 425 SGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEA 484
SG + RALYDY+ + E+SF + +T +E DE GW +G +G G++PANYVE
Sbjct: 371 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDE-GWWRGYGPDGHFGMFPANYVEL 429
Query: 485 IQ 486
I+
Sbjct: 430 IE 431
>gi|23308553 spermatogenesis associated 13 [Homo sapiens]
Length = 652
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/185 (27%), Positives = 85/185 (45%), Gaps = 20/185 (10%)
Query: 314 RREKKKATDGVTLTGINQTGD-QSLPSKPSSTLNVPSNPAQSAQSQSS-YNPFEDEDDTG 371
RR GV+L G NQT + +L ++P+S +P++ ++ S+ + PF T
Sbjct: 21 RRRPISVIGGVSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTP 80
Query: 372 ---STVSEKDDTKAKNVSSYEKTQSYPTDWSDDE-SNNPFSSTDA----------NGDSN 417
V + +A NVSS T+ P+ DD S FS D G+
Sbjct: 81 IGLDRVGRRRQMRASNVSSDGGTE--PSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQL 138
Query: 418 PFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLY 477
++ + G V AL+D+ + EL FKAGD + +E ++ W GR ++ + +
Sbjct: 139 AINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW-GRSEDKE-AWF 196
Query: 478 PANYV 482
PA++V
Sbjct: 197 PASFV 201
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 51.6 bits (122), Expect = 2e-06
Identities = 23/55 (41%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 432 RALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLD-NGQVGLYPANYVEAI 485
RA+YDY Q+ DE+SF+ GD + ++ D+ GW G + G+ G+ PANY+E +
Sbjct: 960 RAMYDYSAQDEDEVSFRDGDYIVNVQPIDD-GWMYGTVQRTGRTGMLPANYIEFV 1013
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,741,904
Number of Sequences: 37866
Number of extensions: 836792
Number of successful extensions: 5699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 552
Number of HSP's that attempted gapping in prelim test: 4338
Number of HSP's gapped (non-prelim): 1639
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.