BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|89353291 calpain 10 isoform c [Homo sapiens] (517 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|89353291 calpain 10 isoform c [Homo sapiens] 1085 0.0 gi|13186302 calpain 10 isoform a [Homo sapiens] 937 0.0 gi|38707981 calpain 12 [Homo sapiens] 231 1e-60 gi|215490104 calpain 11 [Homo sapiens] 231 2e-60 gi|221554549 calpain 8 [Homo sapiens] 218 1e-56 gi|12408656 calpain 1, large subunit [Homo sapiens] 218 1e-56 gi|27765074 calpain 3 isoform c [Homo sapiens] 213 3e-55 gi|157389005 calpain 2 isoform 1 [Homo sapiens] 211 2e-54 gi|4557405 calpain 3 isoform a [Homo sapiens] 209 6e-54 gi|27765072 calpain 3 isoform b [Homo sapiens] 209 6e-54 gi|37577157 calpain 5 [Homo sapiens] 198 9e-51 gi|13186314 calpain 10 isoform g [Homo sapiens] 198 1e-50 gi|5729758 calpain 9 isoform 1 [Homo sapiens] 195 7e-50 gi|47078247 calpain 3 isoform f [Homo sapiens] 192 5e-49 gi|225703100 calpain 2 isoform 2 [Homo sapiens] 188 9e-48 gi|10864059 calpain 10 isoform h [Homo sapiens] 184 1e-46 gi|223468608 calpain 14 [Homo sapiens] 178 9e-45 gi|7705383 calpain 9 isoform 2 [Homo sapiens] 167 2e-41 gi|13186316 calpain 6 [Homo sapiens] 155 1e-37 gi|41152101 calpain 13 [Homo sapiens] 148 1e-35 gi|5032105 small optic lobes [Homo sapiens] 123 4e-28 gi|7656959 calpain 7 [Homo sapiens] 72 2e-12 gi|27765076 calpain 3 isoform d [Homo sapiens] 33 0.82 gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 33 0.82 gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 31 2.4 gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 31 2.4 gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 31 2.4 gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 31 2.4 gi|90903231 huntingtin [Homo sapiens] 30 4.1 gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 30 6.9 >gi|89353291 calpain 10 isoform c [Homo sapiens] Length = 517 Score = 1085 bits (2807), Expect = 0.0 Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120 Query: 121 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG 180 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG Sbjct: 121 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG 180 Query: 181 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF 240 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF Sbjct: 181 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF 240 Query: 241 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE 300 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE Sbjct: 241 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE 300 Query: 301 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG 360 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG Sbjct: 301 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG 360 Query: 361 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV Sbjct: 361 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420 Query: 421 GLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTE 480 GLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTE Sbjct: 421 GLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTE 480 Query: 481 GAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT 517 GAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT Sbjct: 481 GAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT 517 >gi|13186302 calpain 10 isoform a [Homo sapiens] Length = 672 Score = 937 bits (2421), Expect = 0.0 Identities = 447/487 (91%), Positives = 455/487 (93%), Gaps = 2/487 (0%) Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120 Query: 121 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG 180 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG Sbjct: 121 EVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGG 180 Query: 181 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF 240 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF Sbjct: 181 LAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEFHAF 240 Query: 241 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE 300 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE Sbjct: 241 IVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGE 300 Query: 301 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG 360 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG Sbjct: 301 FWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG 360 Query: 361 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV Sbjct: 361 FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAV 420 Query: 421 GLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTE 480 GLHLWKV + R + P +L P+ H Y +EV C L G Y VPST+L D Sbjct: 421 GLHLWKVEK--RRVNLPRVLSMPPVAGTACHAYDREVHLRCELSPGYYLAVPSTFLKDAP 478 Query: 481 GAFTVTI 487 G F + + Sbjct: 479 GEFLLRV 485 Score = 211 bits (538), Expect = 1e-54 Identities = 118/182 (64%), Positives = 129/182 (70%), Gaps = 28/182 (15%) Query: 339 TRALPGAWVKGQSAGGCRNNSGFPSNPKFWLRVSE---PSEVYIAVLQRSRLHAADWAGR 395 T L G+W GQ+AGG RN + +P+NP F V E P V I + Q R Sbjct: 516 TVQLRGSWRVGQTAGGSRNFASYPTNPCFPFSVPEGPGPRCVRITLHQHCR--------- 566 Query: 396 ARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQ 455 S T + P +G H+++VPEGGRSQDAPPLLLQEPLLSCVPHRYAQ Sbjct: 567 ------PSDTEFHP----------IGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRYAQ 610 Query: 456 EVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVM 515 EVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVM Sbjct: 611 EVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMAVM 670 Query: 516 KT 517 KT Sbjct: 671 KT 672 >gi|38707981 calpain 12 [Homo sapiens] Length = 719 Score = 231 bits (589), Expect = 1e-60 Identities = 166/525 (31%), Positives = 244/525 (46%), Gaps = 56/525 (10%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LFRD FPA +L D P ++ + + W RP E CA P+ +D V QG LG+ Sbjct: 45 LFRDPYFPAGPDALGYDQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGN 104 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CWFL A A+L LL +V+PPGQ Y G F ++WQFGRW++V DDRLP Sbjct: 105 CWFLAAAASLTLYPRLLRRVVPPGQDF--QHGYAGVFHFQLWQFGRWMDVVVDDRLPVRE 162 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 G+L F R ++ + FW PLLEK YAK+HGSYE + G + +A VD TGG+ E L+ Sbjct: 163 GKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLR---- 218 Query: 193 SGGQQDRPGRWEHRTCRQLLH-LKDQCLISCCVLSPRAGARE---LGEFHAFIVSDLREL 248 Q+ G + L H L + L+ LS R R L + HA+ ++ ++ Sbjct: 219 ----QNSMGLFS-----ALRHALAKESLVGATALSDRGEYRTEEGLVKGHAYSITGTHKV 269 Query: 249 QGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEEEF 308 + LLR++NPWG W G W + W + LL + ++GEFW+E +F Sbjct: 270 -FLGFTKVRLLRLRNPWGCVEWTGAWSDSCPRWDTLPTECRDALLVKKEDGEFWMELRDF 328 Query: 309 LREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNS-GFPSNPKF 367 L FD + + + + + E H G WV+G ++GG + N+ F +NP+F Sbjct: 329 LLHFDTVQI---CSLSPEVLGPSPEGGGWHVHTFQGRWVRGFNSGGSQPNAETFWTNPQF 385 Query: 368 WLRVSEPSEVYIAVLQRSRLHAADWAG-RARALVGDSHTSWSP---------------AS 411 L + EP E + W G A G + +P Sbjct: 386 RLTLLEPDE------EDDEDEEGPWGGWGAAGARGPARGGRTPKCTVLLSLIQRNRRRLR 439 Query: 412 IPGKHYQAVGLHLWKVPE-------GGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLP 464 G Y VG H++++PE RS P LL+ P ++V+R C L Sbjct: 440 AKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLR---ADRSPLSARRDVTRRCCLR 496 Query: 465 AGTYKVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEV 509 G Y VVPST E FT+ + + ++ +++ LQ + Sbjct: 497 PGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQSL 541 >gi|215490104 calpain 11 [Homo sapiens] Length = 739 Score = 231 bits (588), Expect = 2e-60 Identities = 170/518 (32%), Positives = 246/518 (47%), Gaps = 50/518 (9%) Query: 12 ELFRDAAFPAADSSL-FCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLL 70 ELF D FPA SSL F DL P ++ ++I+W+RP++I P D + QG+L Sbjct: 78 ELFEDPLFPAEPSSLGFKDLG-PNSKNVQNISWQRPKDIINNPLFIMDGISPTDICQGIL 136 Query: 71 GDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPC 130 GDCW L A +L LL +V+P GQ + Y G F +IWQFG+WV V DDRLP Sbjct: 137 GDCWLLAAIGSLTTCPKLLYRVVPRGQSF--KKNYAGIFHFQIWQFGQWVNVVVDDRLPT 194 Query: 131 LAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGV 190 +L F FW LLEK YAK+ GSYE L G + L D TGG+A+ + L+ Sbjct: 195 KNDKLVFVHSTERSEFWSALLEKAYAKLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQ-- 252 Query: 191 AGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARE------LGEFHAFIVSD 244 RP + R R+ ++ L+ C + E L HA+ V+ Sbjct: 253 --------RPPQNLLRLLRKA--VERSSLMGCSIEVTSDSELESMTDKMLVRGHAYSVTG 302 Query: 245 LRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVE 304 L+++ G+ L+R++NPWGR W G W + W +V + + +LL + ++GEFW+ Sbjct: 303 LQDVH-YRGKMETLIRVRNPWGRIEWNGAWSDSAREWEEVASDIQMQLLHKTEDGEFWMS 361 Query: 305 EEEFLREFDELTVG--YPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRNNSG-F 361 ++FL F L + P T +G +S + HT G+W +G SAGGCRN+ G F Sbjct: 362 YQDFLNNFTLLEICNLTPDTLSGDYKSYW------HTTFYEGSWRRGSSAGGCRNHPGTF 415 Query: 362 PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAVG 421 +NP+F + + E + A LV +W A G Q +G Sbjct: 416 WTNPQFKISLPEGDD--------PEDDAEGNVVVCTCLVALMQKNWRHARQQGAQLQTIG 467 Query: 422 LHLWKVP-EGGRSQDAPPLLLQEPLLSCVPHRYAQ------EVSRLCLLPAGTYKVVPST 474 L+ VP E QD L +E H +++ EVS LP G Y ++PST Sbjct: 468 FVLYAVPKEFQNIQDVH--LKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPST 525 Query: 475 YLPDTEGAFTVTIATRIDRPSIHSQEM-LGQFLQEVSV 511 + P + F + + T S E+ + LQE V Sbjct: 526 FEPHRDADFLLRVFTEKHSESWELDEVNYAEQLQEEKV 563 >gi|221554549 calpain 8 [Homo sapiens] Length = 703 Score = 218 bits (554), Expect = 1e-56 Identities = 151/499 (30%), Positives = 240/499 (48%), Gaps = 64/499 (12%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF+D FPA S+L P + + I W+RP E+C +P+ + QG LGD Sbjct: 45 LFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELCPSPQFIVGGATRTDICQGGLGD 104 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CW L A A+L + LL +V+P Q + Y G F + WQ+G WVEV DDRLP Sbjct: 105 CWLLAAIASLTLNEELLYRVVPRDQDF--QENYAGIFHFQFWQYGEWVEVVIDDRLPTKN 162 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 G+L F ++ + FW LLEK YAK++G YE L G + D TGG++E ++LK Sbjct: 163 GQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVEGFEDFTGGISEFYDLK---- 218 Query: 193 SGGQQDRPGRWEHRTCRQLLHLKDQCLISCCV-LSPRAGA-----RELGEFHAFIVSDLR 246 +P ++ R+ L L+ C + +S A A ++L + HA+ V+ + Sbjct: 219 ------KPPANLYQIIRKALCAGS--LLGCSIDVSSAAEAEAITSQKLVKSHAYSVTGVE 270 Query: 247 ELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEE 306 E+ Q G L+R++NPWG W G W + W+ +D EL ++++GEFW+ Sbjct: 271 EVNFQ-GHPEKLIRLRNPWGEVEWSGAWSDDAPEWNHIDPRRKEELDKKVEDGEFWMSLS 329 Query: 307 EFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN-NSGFPSNP 365 +F+R+F L + ++ + ++ L+ G W +G +AGGC+N + + +NP Sbjct: 330 DFVRQFSRLEICNLSPDSLSSEEVHKWNLVLFN----GHWTRGSTAGGCQNYPATYWTNP 385 Query: 366 KFWLRVSEPSE------------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIP 413 +F +R+ E E V + ++Q++R R R +G S Sbjct: 386 QFKIRLDEVDEDQEESIGEPCCTVLLGLMQKNR--------RWRKRIGQGMLS------- 430 Query: 414 GKHYQAVGLHLWKVPEGGRSQDAPPL-----LLQEPLLSCVPHRYAQEVSRLCLLPAGTY 468 +G +++VP+ S L L +P + +EVS LP G Y Sbjct: 431 ------IGYAVYQVPKELESHTDAHLGRDFFLAYQPSARTSTYVNLREVSGRARLPPGEY 484 Query: 469 KVVPSTYLPDTEGAFTVTI 487 VVPST+ P +G F + + Sbjct: 485 LVVPSTFEPFKDGEFCLRV 503 >gi|12408656 calpain 1, large subunit [Homo sapiens] Length = 714 Score = 218 bits (554), Expect = 1e-56 Identities = 159/525 (30%), Positives = 239/525 (45%), Gaps = 64/525 (12%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LFRD AFP SL P + I W+RP E+ + P+ D + QG LGD Sbjct: 55 LFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGD 114 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CW L A A+L + LL +V+P GQ Y G F ++WQFG WV+V DD LP Sbjct: 115 CWLLAAIASLTLNDTLLHRVVPHGQSF--QNGYAGIFHFQLWQFGEWVDVVVDDLLPIKD 172 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 G+L F + FW LLEK YAKV+GSYE L G ++ D TGG+ E + L+ Sbjct: 173 GKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPS 232 Query: 193 SGGQQDRPGRWEHRTCRQLLHLKDQCLISC-----CVLSPRA-GARELGEFHAFIVSDLR 246 Q L L+ L+ C VL A ++L + HA+ V+ + Sbjct: 233 DLYQ------------IILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAK 280 Query: 247 ELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEE 306 ++ GQ + L+R++NPWG W G W + W+ VD +L ++++GEFW+ Sbjct: 281 QV-NYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFR 339 Query: 307 EFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN-NSGFPSNP 365 +F+REF L + +A L+S + +T G W +G +AGGCRN + F NP Sbjct: 340 DFMREFTRLEICNLTPDA--LKSRTIRK--WNTTLYEGTWRRGSTAGGCRNYPATFWVNP 395 Query: 366 KFWLRVSEPSE------------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIP 413 +F +R+ E + +A++Q+ R + Sbjct: 396 QFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRF--------------------- 434 Query: 414 GKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQ-----EVSRLCLLPAGTY 468 G+ + +G +++VP Q A L L + R Q EVS LP G Y Sbjct: 435 GRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEY 494 Query: 469 KVVPSTYLPDTEGAFTVTIATRIDRPSIHSQEMLGQFLQEVSVMA 513 VVPST+ P+ EG F + + ++ + + L + V++ Sbjct: 495 VVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLS 539 >gi|27765074 calpain 3 isoform c [Homo sapiens] Length = 729 Score = 213 bits (543), Expect = 3e-55 Identities = 158/496 (31%), Positives = 239/496 (48%), Gaps = 65/496 (13%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CWFL A A L ++HLL +VIP Q + Y G F + W++G WV+V DD LP Sbjct: 129 CWFLAAIACLTLNQHLLFRVIPHDQSFI--ENYAGIFHFQFWRYGEWVDVVIDDCLPTYN 186 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 +L F++ + FW LLEK YAK+HGSYE L G +A+ D TGG+AE + ++ Sbjct: 187 NQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIR---- 242 Query: 193 SGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSP----RAGARELGEFHAFIVSDLREL 248 D P ++ ++ + S + P A L HA+ V+ L E+ Sbjct: 243 -----DAPSDM-YKIMKKAIERGSLMGCSIDTIIPVQYETRMACGLVRGHAYSVTGLDEV 296 Query: 249 QGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQL-QEGEFWVEEEE 307 + G+ + L+R++NPWG+ W G W + + WS VD + L Q+ ++GEFW+ E+ Sbjct: 297 PFK-GEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYED 355 Query: 308 FLREFDELTVGYPVTEAGHLQSLYTERLLCHTRAL-PGAWVKGQSAGGCRN-NSGFPSNP 365 F+ F +L + +A L +++L T ++ G WV+G SAGGCRN F +NP Sbjct: 356 FIYHFTKLEICNLTADA-----LQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNP 410 Query: 366 KFWLRVSE------PSEV----YIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGK 415 ++ L++ E SEV +A++Q++R + R L G Sbjct: 411 QYRLKLLEEDDDPDDSEVICSFLVALMQKNR-------RKDRKL--------------GA 449 Query: 416 HYQAVGLHLWKVPE--GGRSQDAPP--LLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVV 471 +G +++VP+ G Q L + +EVS+ LP Y +V Sbjct: 450 SLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIV 509 Query: 472 PSTYLPDTEGAFTVTI 487 PSTY P EG F + + Sbjct: 510 PSTYEPHQEGEFILRV 525 >gi|157389005 calpain 2 isoform 1 [Homo sapiens] Length = 700 Score = 211 bits (536), Expect = 2e-54 Identities = 152/500 (30%), Positives = 223/500 (44%), Gaps = 62/500 (12%) Query: 10 ARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGL 69 A LF+D +FPA S+L P + I W+RP EICA P+ + QG Sbjct: 42 AGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGA 101 Query: 70 LGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLP 129 LGDCW L A A+L + +L +V+P Q + Y G F + WQ+G WVEV DDRLP Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSF--QENYAGIFHFQFWQYGEWVEVVVDDRLP 159 Query: 130 CLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKG 189 G L F FW LLEK YAK++G YE L G + D TGG+AE + LK Sbjct: 160 TKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELK- 218 Query: 190 VAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARELGEF------HAFIVS 243 +P + ++ L+ L+ C + A E F HA+ V+ Sbjct: 219 ---------KPPPNLFKIIQKA--LQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVT 267 Query: 244 DLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWV 303 E++ G L+RI+NPWG W G W + W+ +D L + ++GEFW+ Sbjct: 268 GAEEVESN-GSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWM 326 Query: 304 EEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN-NSGFP 362 +FLR + L + +T Y + L + G W +G +AGGCRN + F Sbjct: 327 SFSDFLRHYSRLEI-CNLTPDTLTSDTYKKWKL---TKMDGNWRRGSTAGGCRNYPNTFW 382 Query: 363 SNPKFWLRVSEPSE----------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASI 412 NP++ +++ E E + ++Q+ R R R + D HT Sbjct: 383 MNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR-------RRQRKMGEDMHT------- 428 Query: 413 PGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHR-----YAQEVSRLCLLPAGT 467 +G +++VPE Q L L + R +EV LP G Sbjct: 429 -------IGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGE 481 Query: 468 YKVVPSTYLPDTEGAFTVTI 487 Y +VPST+ P+ +G F + + Sbjct: 482 YILVPSTFEPNKDGDFCIRV 501 >gi|4557405 calpain 3 isoform a [Homo sapiens] Length = 821 Score = 209 bits (531), Expect = 6e-54 Identities = 164/534 (30%), Positives = 242/534 (45%), Gaps = 93/534 (17%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CWFL A A L ++HLL +VIP Q + Y G F + W++G WV+V DD LP Sbjct: 129 CWFLAAIACLTLNQHLLFRVIPHDQSFI--ENYAGIFHFQFWRYGEWVDVVIDDCLPTYN 186 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLA---------- 182 +L F++ + FW LLEK YAK+HGSYE L G +A+ D TGG+A Sbjct: 187 NQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPS 246 Query: 183 ----------ERWNLKGVAGSGGQQ-----DRPGRWEHRTCRQLLHLKDQCLISCCVLSP 227 ER +L G + G G +++ D L+ L P Sbjct: 247 DMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDP 306 Query: 228 RAG-----------------ARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCW 270 R A L HA+ V+ L E+ + G+ + L+R++NPWG+ W Sbjct: 307 RGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFK-GEKVKLVRLRNPWGQVEW 365 Query: 271 QGLWREGGEGWSQVDAAVASELLSQL-QEGEFWVEEEEFLREFDELTVGYPVTEAGHLQS 329 G W + + WS VD + L Q+ ++GEFW+ E+F+ F +L + +A Sbjct: 366 NGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADA----- 420 Query: 330 LYTERLLCHTRAL-PGAWVKGQSAGGCRN-NSGFPSNPKFWLRVSE------PSEV---- 377 L +++L T ++ G WV+G SAGGCRN F +NP++ L++ E SEV Sbjct: 421 LQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSF 480 Query: 378 YIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPE--GGRSQD 435 +A++Q++R + R L G +G +++VP+ G Q Sbjct: 481 LVALMQKNR-------RKDRKL--------------GASLFTIGFAIYEVPKEMHGNKQH 519 Query: 436 APP--LLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 487 L + +EVS+ LP Y +VPSTY P EG F + + Sbjct: 520 LQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRV 573 >gi|27765072 calpain 3 isoform b [Homo sapiens] Length = 815 Score = 209 bits (531), Expect = 6e-54 Identities = 164/534 (30%), Positives = 242/534 (45%), Gaps = 93/534 (17%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CWFL A A L ++HLL +VIP Q + Y G F + W++G WV+V DD LP Sbjct: 129 CWFLAAIACLTLNQHLLFRVIPHDQSFI--ENYAGIFHFQFWRYGEWVDVVIDDCLPTYN 186 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLA---------- 182 +L F++ + FW LLEK YAK+HGSYE L G +A+ D TGG+A Sbjct: 187 NQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPS 246 Query: 183 ----------ERWNLKGVAGSGGQQ-----DRPGRWEHRTCRQLLHLKDQCLISCCVLSP 227 ER +L G + G G +++ D L+ L P Sbjct: 247 DMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDP 306 Query: 228 RAG-----------------ARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCW 270 R A L HA+ V+ L E+ + G+ + L+R++NPWG+ W Sbjct: 307 RGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFK-GEKVKLVRLRNPWGQVEW 365 Query: 271 QGLWREGGEGWSQVDAAVASELLSQL-QEGEFWVEEEEFLREFDELTVGYPVTEAGHLQS 329 G W + + WS VD + L Q+ ++GEFW+ E+F+ F +L + +A Sbjct: 366 NGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADA----- 420 Query: 330 LYTERLLCHTRAL-PGAWVKGQSAGGCRN-NSGFPSNPKFWLRVSE------PSEV---- 377 L +++L T ++ G WV+G SAGGCRN F +NP++ L++ E SEV Sbjct: 421 LQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSF 480 Query: 378 YIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPE--GGRSQD 435 +A++Q++R + R L G +G +++VP+ G Q Sbjct: 481 LVALMQKNR-------RKDRKL--------------GASLFTIGFAIYEVPKEMHGNKQH 519 Query: 436 APP--LLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 487 L + +EVS+ LP Y +VPSTY P EG F + + Sbjct: 520 LQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRV 573 >gi|37577157 calpain 5 [Homo sapiens] Length = 640 Score = 198 bits (504), Expect = 9e-51 Identities = 151/514 (29%), Positives = 231/514 (44%), Gaps = 83/514 (16%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF D FPA D SL+ TP R W+RP+ IC PRLF D + QG +G+ Sbjct: 26 LFEDPLFPATDDSLYYK-GTPGPAVR----WKRPKGICEDPRLFVDGISSHDLHQGQVGN 80 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQE--------YRGSFTCRIWQFGRWVEVTT 124 CWF+ AC++L L +VIP W +QE Y G F W+FG WV+V Sbjct: 81 CWFVAACSSLASRESLWQKVIP----DWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVI 136 Query: 125 DDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAER 184 DDRLP + +L + + FW L+EK YAK+ G Y+ L G ADALVD TGG++E Sbjct: 137 DDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEP 196 Query: 185 WNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARE------LGEFH 238 +L + + R +E R L LIS + + A E L + H Sbjct: 197 IDLTEGDFANDETKRNQLFE----RMLKVHSRGGLISASIKAVTAADMEARLACGLVKGH 252 Query: 239 AFIVSDLRELQGQAG-------QCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASE 291 A+ V+D+R+++ G + + ++R++NPWG R W G W + E W +V + + Sbjct: 253 AYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREK 312 Query: 292 LLSQLQ-EGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWV--- 347 + +Q +GEFW+ E+ R F ++ + V HL T L GAW Sbjct: 313 MGVTVQDDGEFWMTFEDVCRYFTDI-IKCRVINTSHLSIHKT----WEEARLHGAWTLHE 367 Query: 348 --KGQSAGGCRNNSG-FPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGRARALVGDSH 404 + GGC N+ F NP++ V +P + + +Q+ + G+ L Sbjct: 368 DPRQNRGGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGENL----- 422 Query: 405 TSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEV---SRLC 461 A+G ++KV E ++ + + H+ A + SR Sbjct: 423 --------------AIGFDIYKVEEN-----------RQYRMHSLQHKAASSIYINSRSV 457 Query: 462 LL----PAGTYKVVPSTYLPDTEGAFTVTIATRI 491 L P G Y ++P+T+ P G F + + T + Sbjct: 458 FLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDV 491 >gi|13186314 calpain 10 isoform g [Homo sapiens] Length = 139 Score = 198 bits (503), Expect = 1e-50 Identities = 101/131 (77%), Positives = 105/131 (80%), Gaps = 15/131 (11%) Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60 Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120 REGQVKQGLLGDCWFLCACAALQKSRHLLDQV P Q +TC++ W+ Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQ-------LPADWTCKVQPV--WL 111 Query: 121 EVTTDDRLPCL 131 E PCL Sbjct: 112 E------FPCL 116 >gi|5729758 calpain 9 isoform 1 [Homo sapiens] Length = 690 Score = 195 bits (496), Expect = 7e-50 Identities = 147/489 (30%), Positives = 219/489 (44%), Gaps = 59/489 (12%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF DA FPA++SSLF P F W+RP EI P + QG LGD Sbjct: 42 LFEDADFPASNSSLFYS-ERPQIPF----VWKRPGEIVKNPEFILGGATRTDICQGELGD 96 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CW L A A+L ++ L +VIP Q Y G F + WQ W++V DDRLP Sbjct: 97 CWLLAAIASLTLNQKALARVIPQDQSFGPG--YAGIFHFQFWQHSEWLDVVIDDRLPTFR 154 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 RL F + FW LLEK YAK++GSYE L G +A+ D TGG+AE + K Sbjct: 155 DRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTK---- 210 Query: 193 SGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARE------LGEFHAFIVSDLR 246 + P + + LK L+ C + + A E L + HA+ V+ + Sbjct: 211 -----EAPENFYEILEKA---LKRGSLLGCFIDTRSAAESEARTPFGLIKGHAYSVTGID 262 Query: 247 ELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELL-SQLQEGEFWVEE 305 ++ + GQ I L+RI+NPWG+ W G W + W V A L + L +GEFW+ Sbjct: 263 QVSFR-GQRIELIRIRNPWGQVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDDGEFWMAF 321 Query: 306 EEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN-NSGFPSN 364 ++F FD++ + +A +++ + H G+WV+G +AGGCRN F +N Sbjct: 322 KDFKAHFDKVEICNLTPDALEEDAIHKWEVTVH----QGSWVRGSTAGGCRNFLDTFWTN 377 Query: 365 PKFWLRVSEPSE------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQ 418 P+ L ++E E +A++Q+ R + G + Sbjct: 378 PQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF---------------------GANVL 416 Query: 419 AVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPD 478 +G +++ P+ + +EVS LP G Y ++PST+ P Sbjct: 417 TIGYAIYECPDKDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPH 476 Query: 479 TEGAFTVTI 487 E F + I Sbjct: 477 QEADFCLRI 485 >gi|47078247 calpain 3 isoform f [Homo sapiens] Length = 728 Score = 192 bits (489), Expect = 5e-49 Identities = 154/505 (30%), Positives = 229/505 (45%), Gaps = 88/505 (17%) Query: 42 TWRRPQEICATPRLFPDDPREGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWA 101 T ++ EIC PR D + QG LGDCWFL A A L ++HLL +VIP Q Sbjct: 11 TTQQKNEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFI- 69 Query: 102 DQEYRGSFTCRIWQFGRWVEVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGS 161 + Y G F + W++G WV+V DD LP +L F++ + FW LLEK YAK+HGS Sbjct: 70 -ENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGS 128 Query: 162 YEHLWAGQVADALVDLTGGLA--------------------ERWNLKGVAGSGGQQ---- 197 YE L G +A+ D TGG+A ER +L G + G Sbjct: 129 YEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYG 188 Query: 198 -DRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAG-----------------ARELGEFHA 239 G +++ D L+ L PR A L HA Sbjct: 189 TSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHA 248 Query: 240 FIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQL-QE 298 + V+ L E+ + G+ + L+R++NPWG+ W G W + + WS VD + L Q+ ++ Sbjct: 249 YSVTGLDEVPFK-GEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 Query: 299 GEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRAL-PGAWVKGQSAGGCRN 357 GEFW+ E+F+ F +L + +A L +++L T ++ G WV+G SAGGCRN Sbjct: 308 GEFWMSYEDFIYHFTKLEICNLTADA-----LQSDKLQTWTVSVNEGRWVRGCSAGGCRN 362 Query: 358 -NSGFPSNPKFWLRVSE------PSEV----YIAVLQRSRLHAADWAGRARALVGDSHTS 406 F +NP++ L++ E SEV +A++Q++R + R L Sbjct: 363 FPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNR-------RKDRKL------- 408 Query: 407 WSPASIPGKHYQAVGLHLWKVPE--GGRSQDAPP--LLLQEPLLSCVPHRYAQEVSRLCL 462 G +G +++VP+ G Q L + +EVS+ Sbjct: 409 -------GASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFR 461 Query: 463 LPAGTYKVVPSTYLPDTEGAFTVTI 487 LP Y +VPSTY P EG F + + Sbjct: 462 LPPSEYVIVPSTYEPHQEGEFILRV 486 >gi|225703100 calpain 2 isoform 2 [Homo sapiens] Length = 622 Score = 188 bits (478), Expect = 9e-48 Identities = 138/462 (29%), Positives = 204/462 (44%), Gaps = 62/462 (13%) Query: 48 EICATPRLFPDDPREGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRG 107 EICA P+ + QG LGDCW L A A+L + +L +V+P Q + Y G Sbjct: 2 EICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSF--QENYAG 59 Query: 108 SFTCRIWQFGRWVEVTTDDRLPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWA 167 F + WQ+G WVEV DDRLP G L F FW LLEK YAK++G YE L Sbjct: 60 IFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSG 119 Query: 168 GQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSP 227 G + D TGG+AE + LK +P + ++ L+ L+ C + Sbjct: 120 GATTEGFEDFTGGIAEWYELK----------KPPPNLFKIIQKA--LQKGSLLGCSIDIT 167 Query: 228 RAGARELGEF------HAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGW 281 A E F HA+ V+ E++ G L+RI+NPWG W G W + W Sbjct: 168 SAADSEAITFQKLVKGHAYSVTGAEEVESN-GSLQKLIRIRNPWGEVEWTGRWNDNCPSW 226 Query: 282 SQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRA 341 + +D L + ++GEFW+ +FLR + L + +T Y + L Sbjct: 227 NTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEI-CNLTPDTLTSDTYKKWKL---TK 282 Query: 342 LPGAWVKGQSAGGCRN-NSGFPSNPKFWLRVSEPSE----------VYIAVLQRSRLHAA 390 + G W +G +AGGCRN + F NP++ +++ E E + ++Q+ R Sbjct: 283 MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR---- 338 Query: 391 DWAGRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVP 450 R R + D HT +G +++VPE Q L L + Sbjct: 339 ---RRQRKMGEDMHT--------------IGFGIYEVPEELSGQTNIHLSKNFFLTNRAR 381 Query: 451 HR-----YAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 487 R +EV LP G Y +VPST+ P+ +G F + + Sbjct: 382 ERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRV 423 >gi|10864059 calpain 10 isoform h [Homo sapiens] Length = 138 Score = 184 bits (468), Expect = 1e-46 Identities = 91/92 (98%), Positives = 92/92 (100%) Query: 426 KVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTV 485 +VPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTV Sbjct: 47 QVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTV 106 Query: 486 TIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT 517 TIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT Sbjct: 107 TIATRIDRPSIHSQEMLGQFLQEVSVMAVMKT 138 Score = 99.8 bits (247), Expect = 5e-21 Identities = 47/47 (100%), Positives = 47/47 (100%) Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ 47 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ 47 >gi|223468608 calpain 14 [Homo sapiens] Length = 684 Score = 178 bits (452), Expect = 9e-45 Identities = 150/499 (30%), Positives = 229/499 (45%), Gaps = 69/499 (13%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF D +FPA SS+ + L + + W+RP E+ + P+ + + + QG++GD Sbjct: 43 LFEDTSFPATLSSI--GSGSLLQKLPPRLQWKRPPELHSNPQFYFAKAKRLDLCQGIVGD 100 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCL- 131 CWFL A AL + +L +V+P Q ++Y G F W +G WV V DDRLP Sbjct: 101 CWFLAALQALALHQDILSRVVPLNQSF--TEKYAGIFRFWFWHYGNWVPVVIDDRLPVNE 158 Query: 132 AGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVA 191 AG+L F +++FW LLEK YAK+ GSYE L +GQV++ALVD TGG+ NL Sbjct: 159 AGQLVFVSSTYKNLFWGALLEKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAH 218 Query: 192 GSGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLS-PRAGARELGEFHAFIVSDLRELQG 250 G+ W+ + ++ LI C S + L E HA+ ++ +R++ Sbjct: 219 GN--------LWD----ILIEATYNRTLIGCQTHSGEKILENGLVEGHAYTLTGIRKVTC 266 Query: 251 QAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEEEFLR 310 + + L++++NPWG+ W+G W + W + LL + +GEFW+ ++F Sbjct: 267 K-HRPEYLVKLRNPWGKVEWKGDWSDSSSKWELLSPKEKILLLRKDNDGEFWMTLQDFKT 325 Query: 311 EF-----DELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN--NSGFPS 363 F +LT G EA + YT R G W K +AGG R F Sbjct: 326 HFVLLVICKLTPGLLSQEAAQ-KWTYTMR--------EGRWEKRSTAGGQRQLLQDTFWK 376 Query: 364 NPKFWLRVSEPSE---------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPG 414 NP+F L V P E V +++LQ+ R R R Sbjct: 377 NPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPRHRC-----RKR----------------- 414 Query: 415 KHYQAVGLHLWKVPEGGRSQ-DAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVV 471 K A+G +L+++ + Q PP Q P R+ +EVS+ L GTY +V Sbjct: 415 KPLLAIGFYLYRMNKYHDDQRRLPPEFFQRNTPLSQPDRFLKEKEVSQELCLEPGTYLIV 474 Query: 472 PSTYLPDTEGAFTVTIATR 490 P + F + + +R Sbjct: 475 PCILEAHQKSEFVLRVFSR 493 >gi|7705383 calpain 9 isoform 2 [Homo sapiens] Length = 664 Score = 167 bits (423), Expect = 2e-41 Identities = 138/488 (28%), Positives = 208/488 (42%), Gaps = 83/488 (17%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF DA FPA++SSLF P F W+RP EI P + QG LGD Sbjct: 42 LFEDADFPASNSSLFYS-ERPQIPF----VWKRPGEIVKNPEFILGGATRTDICQGELGD 96 Query: 73 CWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLA 132 CW L A A+L ++ L +VIP Q Y G F + WQ W++V DDRLP Sbjct: 97 CWLLAAIASLTLNQKALARVIPQDQSFGPG--YAGIFHFQFWQHSEWLDVVIDDRLPTFR 154 Query: 133 GRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAG 192 RL F + FW LLEK YAK++GSYE L G +A+ D TGG+AE + K Sbjct: 155 DRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTK---- 210 Query: 193 SGGQQDRPGRWEHRTCRQLLHLKDQCLISCCVLSPRAGARE------LGEFHAFIVSDLR 246 + P + + L K L+ C + + A E L + HA+ V+ + Sbjct: 211 -----EAPENFYEILEKAL---KRGSLLGCFIDTRSAAESEARTPFGLIKGHAYSVTGID 262 Query: 247 ELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQLQEGEFWVEEE 306 ++ + GQ I L+RI+NPWG+ W G W + + + Sbjct: 263 QVSFR-GQRIELIRIRNPWGQVEWNGSWSDR-------------------------MAFK 296 Query: 307 EFLREFDELTVGYPVTEAGHLQSLYTERLLCHTRALPGAWVKGQSAGGCRN-NSGFPSNP 365 +F FD++ + +A +++ + H G+WV+G +AGGCRN F +NP Sbjct: 297 DFKAHFDKVEICNLTPDALEEDAIHKWEVTVHQ----GSWVRGSTAGGCRNFLDTFWTNP 352 Query: 366 KFWLRVSEPSE------VYIAVLQRSRLHAADWAGRARALVGDSHTSWSPASIPGKHYQA 419 + L ++E E +A++Q+ R + G + Sbjct: 353 QIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF---------------------GANVLT 391 Query: 420 VGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRYAQEVSRLCLLPAGTYKVVPSTYLPDT 479 +G +++ P+ + +EVS LP G Y ++PST+ P Sbjct: 392 IGYAIYECPDKDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQ 451 Query: 480 EGAFTVTI 487 E F + I Sbjct: 452 EADFCLRI 459 >gi|13186316 calpain 6 [Homo sapiens] Length = 641 Score = 155 bits (391), Expect = 1e-37 Identities = 127/413 (30%), Positives = 185/413 (44%), Gaps = 53/413 (12%) Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72 LF D F + SLF + P + W+RPQ+IC P L + Q+ QG LG Sbjct: 26 LFCDPTFLPENDSLFYNRLLP-----GKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGH 80 Query: 73 CWFLCA--CAALQKSRHLLDQVIPPGQPSWADQE---YRGSFTCRIWQFGRWVEVTTDDR 127 + A C A+Q+S H + + W Q+ Y G F R W FG W EV DD Sbjct: 81 KPMVSAFSCLAVQES-HWTKTIPNHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDL 139 Query: 128 LPCLAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNL 187 LP + G L FS + FW LLEK YAK+ G YE L + D +VD TG LAE ++ Sbjct: 140 LPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDM 199 Query: 188 KGVAGSGGQQDRPGRWEHRTCRQLLH-LKDQCLISCCVLSPRAGARE------LGEFHAF 240 + G+ +++ +L LI C + SP +E L + H + Sbjct: 200 Q-----KGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTY 254 Query: 241 IVSDLRELQ-GQ------AGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASEL- 292 ++D+R+++ G+ + + + ++R++NP GR+ W G W E E W Q+ A+ L Sbjct: 255 TMTDIRKIRLGERLVEVFSAEKVYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLG 314 Query: 293 LSQLQEGEFWVEEEEFLREFDEL----TVGYPVTEAGHLQSLYTERLLCHTRALPGAWVK 348 L +GEFW+ E+F R F +L V P+ L+S+ G W Sbjct: 315 LVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELESVL------------GCWTV 362 Query: 349 GQS-----AGGCRNN-SGFPSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAGR 395 +GGC NN F NP++ V E I LQ+ L GR Sbjct: 363 DDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGR 415 >gi|41152101 calpain 13 [Homo sapiens] Length = 669 Score = 148 bits (373), Expect = 1e-35 Identities = 122/389 (31%), Positives = 180/389 (46%), Gaps = 69/389 (17%) Query: 14 FRDAAFPAADSSLFCDLSTPLAQFR-EDITWRRPQEICATPRLFP-DDPREGQVKQGLLG 71 F+D FPAADSS+ L L + R ++ W+RPQ++ P F DD ++QG Sbjct: 35 FKDETFPAADSSIGQKL---LQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAA 91 Query: 72 DCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCL 131 DCWFL A +L ++ +++ S +Y G F R WQ G+WVEV DDRLP Sbjct: 92 DCWFLAALGSLTQNPQYRQKILMVQSFS---HQYAGIFRFRFWQCGQWVEVVIDDRLPVQ 148 Query: 132 AGRLCFSRCQREDV-FWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGV 190 + F R + ++ FW LLEK YAK+ GSY L G + DALVDLTGG+ +L Sbjct: 149 GDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSYSDLHYGFLEDALVDLTGGVITNIHL--- 205 Query: 191 AGSGGQQDRPGRWEHRTCRQLLH-----LKDQCLISCCVLS---PRAGARELG--EFHAF 240 H + L+ K LI+C S A A E G HA+ Sbjct: 206 --------------HSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQAMENGLVSLHAY 251 Query: 241 IVSDLRELQGQAGQCILLLRIQNP--WGRRCWQGLWREGGEGWSQVDAAVASELLSQLQE 298 V+ ++Q + G ++ + NP WG W+G W +G + W + S+L + ++ Sbjct: 252 TVTGAEQIQYRRG-WEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPRKSQLHKKRED 310 Query: 299 GEFWVEEEEFLREFDELTV--GYPVTEAGHLQSLYTERLLCHTRALPGAW---------V 347 GEFW+ ++F ++F + + P+T L H L W + Sbjct: 311 GEFWMSCQDFQQKFIAMFICSEIPIT-------------LDHGNTLHEGWSQIMFRKQVI 357 Query: 348 KGQSAGGCRNNSGFPSNPKFWLRVSEPSE 376 G +AGG RN++ +F V EP E Sbjct: 358 LGNTAGGPRNDA------QFNFSVQEPME 380 >gi|5032105 small optic lobes [Homo sapiens] Length = 1086 Score = 123 bits (309), Expect = 4e-28 Identities = 102/322 (31%), Positives = 149/322 (46%), Gaps = 38/322 (11%) Query: 14 FRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP---------REGQ 64 F D +FP S+ + Q W RPQEI + +F D R Sbjct: 488 FVDDSFPPGPESVGFPAGDSVQQRVRQ--WLRPQEINCS--VFRDHRATWSVFHTLRPSD 543 Query: 65 VKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWVEVTT 124 + QGLLG+CWFL A A L + L+++V+ G++ R+ + G W V Sbjct: 544 ILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLC-----AEGAYQVRLCKDGTWTTVLV 598 Query: 125 DDRLPC-LAGRLCFSRCQREDVFWLPLLEKVYAKVHGSYEHLWAGQVADALVDLTGGLAE 183 DD LPC AG L FS+ QR+ + W+ L+EK AK+HGSY L AG+ + L LTG E Sbjct: 599 DDMLPCDEAGCLLFSQAQRKQL-WVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCE 657 Query: 184 RWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKDQCLI--SC-----CVLSPRAGARELGE 236 L+ S ++ P + + L + L+ SC V + L Sbjct: 658 SLALQ--LSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRP 715 Query: 237 FHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWREGGEGWSQVDAAVASELLSQ- 295 HA+ + D+R++QG LLR++NPWGR W G W + W + EL+ Sbjct: 716 RHAYSILDVRDVQGTR-----LLRLRNPWGRFSWNGSW---SDEWPHWPGHLRGELMPHG 767 Query: 296 LQEGEFWVEEEEFLREFDELTV 317 EG FW+E +F+R FD + + Sbjct: 768 SSEGVFWMEYGDFVRYFDSVDI 789 >gi|7656959 calpain 7 [Homo sapiens] Length = 813 Score = 71.6 bits (174), Expect = 2e-12 Identities = 85/346 (24%), Positives = 139/346 (40%), Gaps = 41/346 (11%) Query: 43 WRRPQEICATPRLFPDDPREGQVKQGLLGDCWF---LCACAALQK--SRHLLDQVIPPGQ 97 W RP+++ P + +KQ ++ DC F L AA ++ ++ L+ +I P Q Sbjct: 261 WVRPEDLTNNPTMIYT-VSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITGIIYP-Q 318 Query: 98 PSWADQEYR--GSFTCRIWQFGRWVEVTTDDRLPC-LAGRLCFSRCQREDVFWLPLLEKV 154 + EY G + ++ G +V DD+LP G L S + W+ L+EK Sbjct: 319 NKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKA 378 Query: 155 YAKVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHL 214 Y KV G Y+ + D L LTG + ER +A Q R Q H Sbjct: 379 YMKVMGGYDFPGSNSNID-LHALTGWIPER-----IAMHSDSQTFSKDNSFRMLYQRFHK 432 Query: 215 KDQCLISCCVLSPRAGARELG--EFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQG 272 D + + + A + G HA+ V D+RE +G + ++++NPW W+G Sbjct: 433 GDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKG-----LRFIQLKNPWSHLRWKG 487 Query: 273 LWREGG-EGWS---QVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQ 328 + E + W+ Q ++ G FW+ +D+L Y V Sbjct: 488 RYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWI-------SWDDLCQYYDVIYLSWNP 540 Query: 329 SLYTERLLCHTRALPGAWVKGQSAGGCRNNSGFPSNPKFWLRVSEP 374 L+ E H+ W Q G ++ +NP++ L V P Sbjct: 541 GLFKESTCIHS-----TWDAKQ--GPVKDAYSLANNPQYKLEVQCP 579 Score = 30.8 bits (68), Expect = 3.1 Identities = 10/21 (47%), Positives = 16/21 (76%) Query: 463 LPAGTYKVVPSTYLPDTEGAF 483 +P+G + ++PST+LP EG F Sbjct: 777 IPSGIFNIIPSTFLPKQEGPF 797 >gi|27765076 calpain 3 isoform d [Homo sapiens] Length = 309 Score = 32.7 bits (73), Expect = 0.82 Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 455 QEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 487 +EVS+ LP Y +VPSTY P EG F + + Sbjct: 29 REVSQRFRLPPSEYVIVPSTYEPHQEGEFILRV 61 >gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens] Length = 1331 Score = 32.7 bits (73), Expect = 0.82 Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 10/106 (9%) Query: 343 PGAWVKGQSAGGCRNNSGFPSNPKFWLRVSEPSEVYI-AVLQRSRLHAADWAGRARALVG 401 PG + K GG S S+ WL+V + I A+ + R ++DW + R L Sbjct: 60 PG-YAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYS 118 Query: 402 DSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLS 447 D+ +W P G ++W P S LQ P+++ Sbjct: 119 DTGRNWKPYHQDG--------NIWAFPGNINSDGVVRHELQHPIIA 156 >gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo sapiens] Length = 448 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/46 (32%), Positives = 26/46 (56%) Query: 394 GRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPL 439 G A + G SH+ +P++IP K + A+ L + ++P +D PL Sbjct: 28 GSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPL 73 >gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo sapiens] Length = 484 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/46 (32%), Positives = 26/46 (56%) Query: 394 GRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPL 439 G A + G SH+ +P++IP K + A+ L + ++P +D PL Sbjct: 28 GSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPL 73 >gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo sapiens] Length = 485 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/46 (32%), Positives = 26/46 (56%) Query: 394 GRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPL 439 G A + G SH+ +P++IP K + A+ L + ++P +D PL Sbjct: 28 GSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPL 73 >gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sapiens] Length = 486 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/46 (32%), Positives = 26/46 (56%) Query: 394 GRARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPL 439 G A + G SH+ +P++IP K + A+ L + ++P +D PL Sbjct: 28 GSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPL 73 >gi|90903231 huntingtin [Homo sapiens] Length = 3144 Score = 30.4 bits (67), Expect = 4.1 Identities = 11/24 (45%), Positives = 15/24 (62%) Query: 380 AVLQRSRLHAADWAGRARALVGDS 403 ++L RSR H DW G R L G++ Sbjct: 780 SILSRSRFHVGDWMGTIRTLTGNT 803 >gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 1472 Score = 29.6 bits (65), Expect = 6.9 Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 4/44 (9%) Query: 93 IPPGQPSWADQEYRGSFTCRIWQFGRWVEVTTDDRLPCLAGRLC 136 + PGQ WAD+ + TC G +VT D+ C AG C Sbjct: 869 LAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSCPAGERC 908 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.454 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,215,854 Number of Sequences: 37866 Number of extensions: 1157425 Number of successful extensions: 2436 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 2314 Number of HSP's gapped (non-prelim): 63 length of query: 517 length of database: 18,247,518 effective HSP length: 107 effective length of query: 410 effective length of database: 14,195,856 effective search space: 5820300960 effective search space used: 5820300960 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.