Search of human proteins with 7662350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662350 cell recognition molecule Caspr2 precursor [Homo
sapiens]
         (1331 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...  2771   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]       1338   0.0  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...  1286   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]          1219   0.0  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...  1217   0.0  
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...  1209   0.0  
gi|4505463 contactin associated protein 1 precursor [Homo sapiens]   1145   0.0  
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...   936   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...   499   e-141
gi|239743729 PREDICTED: similar to contactin associated protein-...   366   e-101
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        166   1e-40
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   166   1e-40
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       159   2e-38
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             154   7e-37
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       136   1e-31
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       130   6e-30
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...   100   2e-20
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...    95   4e-19
gi|105990535 coagulation factor V precursor [Homo sapiens]             92   3e-18
gi|33469931 EGF-like, fibronectin type III and laminin G domains...    88   6e-17
gi|33469929 EGF-like, fibronectin type III and laminin G domains...    88   6e-17
gi|10835083 X-linked juvenile retinoschisis protein precursor [H...    87   8e-17
gi|219842266 usherin isoform B [Homo sapiens]                          86   3e-16
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...    85   4e-16
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    84   7e-16
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...    84   9e-16
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    84   9e-16
gi|4504229 glycophorin C isoform 1 [Homo sapiens]                      82   4e-15
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...    81   6e-15
gi|31317224 EGF-like repeats and discoidin I-like domains-contai...    81   6e-15

>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
          Length = 1331

 Score = 2771 bits (7182), Expect = 0.0
 Identities = 1331/1331 (100%), Positives = 1331/1331 (100%)

Query: 1    MQAAPRAGCGAALLLWIVSSCLCRAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGSYSP 60
            MQAAPRAGCGAALLLWIVSSCLCRAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGSYSP
Sbjct: 1    MQAAPRAGCGAALLLWIVSSCLCRAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGSYSP 60

Query: 61   GYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDT 120
            GYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDT
Sbjct: 61   GYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDT 120

Query: 121  GRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYG 180
            GRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYG
Sbjct: 121  GRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYG 180

Query: 181  CSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLEL 240
            CSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLEL
Sbjct: 181  CSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLEL 240

Query: 241  KKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHFR 300
            KKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHFR
Sbjct: 241  KKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHFR 300

Query: 301  TNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSN 360
            TNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSN
Sbjct: 301  TNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSN 360

Query: 361  VGNLSFSCVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLG 420
            VGNLSFSCVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLG
Sbjct: 361  VGNLSFSCVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLG 420

Query: 421  NVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEAS 480
            NVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEAS
Sbjct: 421  NVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEAS 480

Query: 481  AVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRK 540
            AVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRK
Sbjct: 481  AVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRK 540

Query: 541  PGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCE 600
            PGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCE
Sbjct: 541  PGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCE 600

Query: 601  AYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSV 660
            AYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSV
Sbjct: 601  AYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSV 660

Query: 661  TQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGG 720
            TQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGG
Sbjct: 661  TQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGG 720

Query: 721  SGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGS 780
            SGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGS
Sbjct: 721  SGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGS 780

Query: 781  EAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENM 840
            EAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENM
Sbjct: 781  EAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENM 840

Query: 841  GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR 900
            GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR
Sbjct: 841  GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR 900

Query: 901  LPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFI 960
            LPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFI
Sbjct: 901  LPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFI 960

Query: 961  SGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQ 1020
            SGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQ
Sbjct: 961  SGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQ 1020

Query: 1021 APATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVK 1080
            APATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVK
Sbjct: 1021 APATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVK 1080

Query: 1081 PTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPS 1140
            PTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPS
Sbjct: 1081 PTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPS 1140

Query: 1141 SSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNAS 1200
            SSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNAS
Sbjct: 1141 SSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNAS 1200

Query: 1201 AHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRN 1260
            AHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRN
Sbjct: 1201 AHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRN 1260

Query: 1261 SAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTE 1320
            SAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTE
Sbjct: 1261 SAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTE 1320

Query: 1321 TIDESKKEWLI 1331
            TIDESKKEWLI
Sbjct: 1321 TIDESKKEWLI 1331


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 1338 bits (3463), Expect = 0.0
 Identities = 662/1316 (50%), Positives = 901/1316 (68%), Gaps = 48/1316 (3%)

Query: 30   STSQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDF 89
            +T+  CD+PL S L  +AFSSSS ++G++SP  A++N R G GGWSP+DS+  QWLQ+D 
Sbjct: 25   ATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWSPADSNAQQWLQMDL 82

Query: 90   GNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHE 149
            GNR +I+A+ATQGRY SSDWVT Y +++SDTGRNWK Y Q+ +IW F GN+N+D VV H+
Sbjct: 83   GNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHK 142

Query: 150  LQHPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLK 209
            L H + AR+VR VPL+WN  G+IG+R+EVYGCSY +DV +FDG   L YRF  K M TLK
Sbjct: 143  LLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLK 202

Query: 210  DVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGS 269
            DVI+L FK+ + +GV+ HGEGQ+GD+ITLEL+K +L L LNLG ++        S   GS
Sbjct: 203  DVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGS 262

Query: 270  LLDDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSS 329
            LLDD HWHSV+IER G+ +N T+D+  QHFRT GE D LD+DYE++FGGIP  GKP +  
Sbjct: 263  LLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFL 322

Query: 330  RKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFF--NATSYLEVP 387
            +KNF GC+E++ YNGVNI DLA+R+K +    GN++FSC EP  VP+ F  ++ SYL +P
Sbjct: 323  KKNFHGCIENLYYNGVNIIDLAKRRKHQ-IYTGNVTFSCSEPQIVPITFVNSSGSYLLLP 381

Query: 388  GRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQ--I 445
            G    D  SVSFQFRTWN +GLL+ +  ++  G + + L     G  + +   KM++   
Sbjct: 382  GTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLE----GGILRLVIQKMTERVA 437

Query: 446  DISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQM 505
            +I +GS LNDG WH V   A+ N   LT+D + A     ++ +Q+ +G  Y+FGG  + +
Sbjct: 438  EILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNL 497

Query: 506  NNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEH 565
             +S       +FQGCM+LI +D+Q  +L  V Q   G+F+++ ID+C+I DRC+PN+CEH
Sbjct: 498  TDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEH 557

Query: 566  GGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPL 625
            GG CSQ+W +F C C +T Y+GATCHNSIYE SCE Y+H G T+ +++ID DGSGPLGPL
Sbjct: 558  GGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPL 617

Query: 626  KVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQY 685
            +VYCN+TEDK+WT V H+    T V G NPEK     L Y  SM+Q+ A+ D +E+CEQ 
Sbjct: 618  QVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQE 677

Query: 686  VSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNC 745
            V+Y C+ SRLLNTPDG+P+TWW+G++NE+H YWGGS PG+Q+C CG++ +C D +++CNC
Sbjct: 678  VAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNC 737

Query: 746  DADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPN 805
            DAD  +W  D GFLS+KDHLPV+Q+V+ DTDR  SEA   +GPLRC GDR +WNA SF  
Sbjct: 738  DADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYT 797

Query: 806  PSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNG 865
             +SYLHF TF  E SADISF+FKT    GVFLEN+G +DFI+LE+ S +E++F+ DVGNG
Sbjct: 798  EASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNG 857

Query: 866  PVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVG 925
            PVE+VV+SP+ LND+QWH V AERN+K+ SLQVD LP+  R+   EGH RL+L SQLFVG
Sbjct: 858  PVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVG 917

Query: 926  GAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERY 984
            G    Q+GFLGCIRSL +NG  +DLEERAKVTSG   GC GHC+SYG+ C NGGKC+E++
Sbjct: 918  GTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKH 977

Query: 985  HGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP---ATNARDSSSRV--DNAPDQ 1039
            +GY CDC+N+ Y+G FC K+V A FE G  + Y FQ P     N   SSS +  D+AP +
Sbjct: 978  NGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSK 1037

Query: 1040 QNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYN 1099
            +N         I  SF TT+AP +LL+I+S + DF+ VL+   GSLQ+RY+L    E + 
Sbjct: 1038 EN---------IALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL-NKEETHV 1087

Query: 1100 IDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIE 1159
              +D  N AN + H + I R  + + +++D    +SY+   S +  F   +SL LGKV E
Sbjct: 1088 FTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNF--SPEVEFRVIRSLTLGKVTE 1145

Query: 1160 TGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCG---- 1215
               +D E+ K N  GF GC+S VQ+N IAPLKAALR     A V + G L ES+CG    
Sbjct: 1146 NLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATV-APVTVHGTLTESSCGFMVD 1204

Query: 1216 ASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTI 1275
            +    ++ + S++DP+                 + + + N V  +SA+IGGVIAVVIF I
Sbjct: 1205 SDVNAVTTVHSSSDPFG-------------KTDEREPLTNAVRSDSAVIGGVIAVVIFII 1251

Query: 1276 LCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI 1331
             C +  + R++++HK ++ T++ K  E  E+ D++   N+ +   T+ E K+E+ I
Sbjct: 1252 FCIIGIMTRFLYQHKQSHRTSQMKEKEYPENLDSS-FRNEIDLQNTVSECKREYFI 1306


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
          Length = 1308

 Score = 1286 bits (3328), Expect = 0.0
 Identities = 634/1302 (48%), Positives = 873/1302 (67%), Gaps = 27/1302 (2%)

Query: 32   SQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGN 91
            S  CD+PLVS LP  +FSSSS +S S+ PG+A++N+R GAGGWSP  S+ YQWLQ+D G 
Sbjct: 28   SYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 87

Query: 92   RKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQ 151
            R +++A+ATQG Y SS+WVT Y +++SD+G NWK Y Q+ +IW F GN N+D VV + LQ
Sbjct: 88   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 147

Query: 152  HPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDV 211
              I AR++R +PL+WN +GRIG+RIEV+GC+Y ++V++ DG   L YRF  K +  +KD+
Sbjct: 148  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 207

Query: 212  IALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLL 271
            I+L FKT +S+G++LH EG  GD+ITL+L++A+L L +N G  +L       ++  GSLL
Sbjct: 208  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 267

Query: 272  DDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRK 331
            DD HWHSV+I+R G+ +N T+D    HF   GEF+ ++LDYEI+FGGIP  GK  S   +
Sbjct: 268  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHR 327

Query: 332  NFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRL 390
            NF GC+E++ YNGV+I DLA+++K +   +GN+SFSC +P ++PV F ++ SYL +P   
Sbjct: 328  NFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFS 387

Query: 391  NQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSG 450
             ++  S +FQFRTWN  GLL+FS      G + + L++ K  +  N+ Q      DI++G
Sbjct: 388  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGK--LKSNLYQPGKLPSDITAG 445

Query: 451  SGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSH 510
              LNDGQWH V   AK+N   + +DG  ASA     P Q+ +G  Y+FGG  ++   S  
Sbjct: 446  VELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKC 505

Query: 511  SVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCS 570
                  FQGCM+LI +  ++V+L  V Q   G+F+++ ID C I DRC+PN+CEHGG+CS
Sbjct: 506  KSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECS 565

Query: 571  QTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCN 630
            Q+W +F C C  TGY GATCHNSIYE SCEAYKH G TS +Y+ID DGSGPL P  +YCN
Sbjct: 566  QSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCN 625

Query: 631  MTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFC 690
            MTE   WTI+ H+    T V   NPE        Y ASM+Q+ A  + AE+CEQ  +Y+C
Sbjct: 626  MTE-TAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYC 684

Query: 691  KMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYK 750
            K SRL+N  DG+P +WWVG+ NE   YWGGS P +QKC CG+E NC D +YYCNCDAD  
Sbjct: 685  KKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRN 744

Query: 751  QWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYL 810
            +W  D G L+YK+HLPV+++V+ DT R  SEA   +GPL CQGDR++WN+ASF   +SYL
Sbjct: 745  EWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYL 804

Query: 811  HFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIV 870
            HF TF GE SAD+SF+FKT    GVFLEN+G  DFI++EL+S T V+FSFDVGNGP EI 
Sbjct: 805  HFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEIS 864

Query: 871  VRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGG 929
            V+SPT  ND+QWH V  ERN+K+ASLQVD+L  + + AP +GH  L+L SQLFVGG A  
Sbjct: 865  VQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATR 924

Query: 930  QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSC 989
            Q+GFLGCIRSL++NG+TLDLEERA+VT     GC GHC+SYG  C NGGKC ER  G+ C
Sbjct: 925  QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 984

Query: 990  DCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LA 1047
            DC+ +AY G FC+ ++ A+F  G  + YNFQ     +++SSS         + H D  L+
Sbjct: 985  DCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHA------ASFHGDMKLS 1038

Query: 1048 QEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNM 1107
            +E I+FSF TT+ P +LL++SSF  ++L+V++   GSLQIRY L   +EP  ++ D +NM
Sbjct: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1098

Query: 1108 ANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEI 1167
            A+GQ H + I R E  +F+++D       HL  SS T F++ KSL LG+++E   +DQ+ 
Sbjct: 1099 ADGQLHHIMINREEGVVFIEIDDNRRRQVHL--SSGTEFSAVKSLVLGRILEHSDVDQDT 1156

Query: 1168 HKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSA 1227
                  GFTGCLS VQ + +APLKAAL  ++    V + G + ES+C A P T +     
Sbjct: 1157 ALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDP-VTVTGHVTESSCMAQPGTDATSRER 1215

Query: 1228 TDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMF 1287
            T  +         AD        + + N +  +SA+IGG+IAVVIF +LC     +R ++
Sbjct: 1216 THSF---------ADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IY 1265

Query: 1288 RHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEW 1329
            + K  Y  +EAK +E+ +SA+ A++ ++ N    ++E++KE+
Sbjct: 1266 QQKRLYKRSEAKRSENVDSAE-AVLKSELNIQNAVNENQKEY 1306


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 1219 bits (3153), Expect = 0.0
 Identities = 609/1277 (47%), Positives = 838/1277 (65%), Gaps = 26/1277 (2%)

Query: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
            CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 31   CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
            ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
             AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L YR   K +K ++DVI+L
Sbjct: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYRLDKKPLKPIRDVISL 210

Query: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
             FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
            HWHSV+IE     +N T+D+   HF+  G+  YLDL++EI+FGGIP  G+  +  RK+F 
Sbjct: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEISFGGIPTPGRSRAFRRKSFH 330

Query: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393
            GC+E++ YNGV++T+LA++ K +   +GN+SFSC +P TVPV F ++ SYL +PG   +D
Sbjct: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453
              SV+FQFRTWN  G L+F       G+  + L + K  + +++ Q   S  ++++G+GL
Sbjct: 391  KVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGK--LKLSLFQPGQSPRNVTAGAGL 448

Query: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513
            NDGQWH V F AK +   + +D D  +AV+    + + +G+ Y+FGG L+  + S     
Sbjct: 449  NDGQWHSVSFSAKWSHMNVVVDDD--TAVQPLVAVLIDSGDTYYFGGCLDNSSGSGCKSP 506

Query: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573
               FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++CEHGG+CSQ+W
Sbjct: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566

Query: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633
            D+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLGP  VYCNMT 
Sbjct: 567  DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTA 626

Query: 634  DKVWTIVSHDLQMQTPVVGY-NPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKM 692
            D  WT+V H       + G  +    S     Y+A   Q+ +  + AE CEQ ++  C  
Sbjct: 627  DAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLRSAVNLAERCEQRLALRCGT 686

Query: 693  SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752
            +R  ++ DG+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W
Sbjct: 687  ARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEW 746

Query: 753  RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812
              D   LS K+HLPV+Q+V+ D  R  SEA  ++GPL C+GD+++WN+ASF   +SYLHF
Sbjct: 747  TSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHF 806

Query: 813  STFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVR 872
              F GE +AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+
Sbjct: 807  PAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQ 866

Query: 873  SPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQ 931
            SPTP ND+QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+GG A  Q+
Sbjct: 867  SPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR 926

Query: 932  GFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDC 991
            GFLGCIRSL++NGV LDLEERA VT G   GC+GHC++YG  C NGG+C E+  G +CDC
Sbjct: 927  GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDC 986

Query: 992  SNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQE 1049
            + +AYDG FC+ ++ A+F  G  + Y+FQ   T + +SSS V +       H D  L +E
Sbjct: 987  AFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL------HRDVTLTRE 1040

Query: 1050 EIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMAN 1109
             I  SF TT+ P +LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+
Sbjct: 1041 MITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 1100

Query: 1110 GQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHK 1169
            GQ H V I R E  + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +
Sbjct: 1101 GQLHQVKINREEAVVMVEVNQ--STKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRR 1158

Query: 1170 YNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSAT 1228
              T GFTGCLS V+F + APLKAALR +  S  V ++G +   + C A   + SP     
Sbjct: 1159 AATSGFTGCLSAVRFGRAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELA 1217

Query: 1229 DPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFR 1288
                     S  AD      +G+ + N   R+SA+IGGVIAVVIF +LC     IR +++
Sbjct: 1218 PRLAGGAGRSGPAD------EGEPLVNADRRDSAVIGGVIAVVIFILLCITAIAIR-IYQ 1270

Query: 1289 HKGTYHTNEAKGAESAE 1305
             +     NE+K ++  E
Sbjct: 1271 QRKLRKENESKVSKKEE 1287


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 1217 bits (3148), Expect = 0.0
 Identities = 610/1299 (46%), Positives = 838/1299 (64%), Gaps = 75/1299 (5%)

Query: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
            CD+PLVS LP  +FSSSS +S S+ PG+A++N+R GAGGWSP  S+ YQWLQ+D G R +
Sbjct: 6    CDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERME 65

Query: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
            ++A+ATQG Y SS+WVT Y +++SD+G NWK Y Q+ +IW F GN N+D VV + LQ  I
Sbjct: 66   VTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSI 125

Query: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
             AR++R +PL+WN +GRIG+RIEV+GC+Y ++V++ DG   L YRF  K +  +KD+I+L
Sbjct: 126  KARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISL 185

Query: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
             FKT +S+G++LH EG  GD+ITL+L++A+L L +N G  +L       ++  GSLLDD 
Sbjct: 186  KFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQ 245

Query: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
            HWHSV+I+R G+ +N T+D    HF   GEF+ ++LDYE                     
Sbjct: 246  HWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE--------------------- 284

Query: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393
                                       GN+SFSC +P ++PV F ++ SYL +P    ++
Sbjct: 285  ---------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEE 317

Query: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453
              S +FQFRTWN  GLL+FS      G + + L++ K+    N+ Q      DI++G  L
Sbjct: 318  EVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKL--KSNLYQPGKLPSDITAGVEL 375

Query: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513
            NDGQWH V   AK+N   + +DG  ASA     P Q+ +G  Y+FGG  ++   S     
Sbjct: 376  NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSP 435

Query: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573
               FQGCM+LI +  ++V+L  V Q   G+F+++ ID C I DRC+PN+CEHGG+CSQ+W
Sbjct: 436  LGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSW 495

Query: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633
             +F C C  TGY GATCHNSIYE SCEAYKH G TS +Y+ID DGSGPL P  +YCNMTE
Sbjct: 496  STFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTE 555

Query: 634  DKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKMS 693
               WTI+ H+    T V   NPE        Y ASM+Q+ A  + AE+CEQ  +Y+CK S
Sbjct: 556  T-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 614

Query: 694  RLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWR 753
            RL+N  DG+P +WWVG+ NE   YWGGS P +QKC CG+E NC D +YYCNCDAD  +W 
Sbjct: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674

Query: 754  KDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFS 813
             D G L+YK+HLPV+++V+ DT R  SEA   +GPL CQGDR++WN+ASF   +SYLHF 
Sbjct: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734

Query: 814  TFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRS 873
            TF GE SAD+SF+FKT    GVFLEN+G  DFI++EL+S T V+FSFDVGNGP EI V+S
Sbjct: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794

Query: 874  PTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQG 932
            PT  ND+QWH V  ERN+K+ASLQVD+L  + + AP +GH  L+L SQLFVGG A  Q+G
Sbjct: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854

Query: 933  FLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCS 992
            FLGCIRSL++NG+TLDLEERA+VT     GC GHC+SYG  C NGGKC ER  G+ CDC+
Sbjct: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914

Query: 993  NTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEE 1050
             +AY G FC+ ++ A+F  G  + YNFQ     +++SSS         + H D  L++E 
Sbjct: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHA------ASFHGDMKLSREM 968

Query: 1051 IRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANG 1110
            I+FSF TT+ P +LL++SSF  ++L+V++   GSLQIRY L   +EP  ++ D +NMA+G
Sbjct: 969  IKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADG 1028

Query: 1111 QPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKY 1170
            Q H + I R E  +F+++D       HL  SS T F++ KSL LG+++E   +DQ+    
Sbjct: 1029 QLHHIMINREEGVVFIEIDDNRRRQVHL--SSGTEFSAVKSLVLGRILEHSDVDQDTALA 1086

Query: 1171 NTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDP 1230
               GFTGCLS VQ + +APLKAAL  ++    V + G + ES+C A P T +     T  
Sbjct: 1087 GAQGFTGCLSAVQLSHVAPLKAALHPSHPDP-VTVTGHVTESSCMAQPGTDATSRERTHS 1145

Query: 1231 WHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHK 1290
            +         AD        + + N +  +SA+IGG+IAVVIF +LC     +R +++ K
Sbjct: 1146 F---------ADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQK 1195

Query: 1291 GTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEW 1329
              Y  +EAK +E+ +SA+ A++ ++ N    ++E++KE+
Sbjct: 1196 RLYKRSEAKRSENVDSAE-AVLKSELNIQNAVNENQKEY 1233


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
            [Homo sapiens]
          Length = 1288

 Score = 1209 bits (3128), Expect = 0.0
 Identities = 603/1275 (47%), Positives = 834/1275 (65%), Gaps = 22/1275 (1%)

Query: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
            CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 31   CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
            ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
             AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L Y    K +K ++DVI+L
Sbjct: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
             FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
            HWHSV+IE     +N T+D+   HF+  G+   LDL++EI+FGGI   G+  + +RK+F 
Sbjct: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330

Query: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393
            GC+E++ YNGV++T+LA++ K +   +GN+SFSC +P TVPV F ++ SYL +PG   +D
Sbjct: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453
              SV+FQFRTWN  G L+F       G+  + L + K  + +++ Q   S  ++++G+GL
Sbjct: 391  KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGK--LKLSLFQAGQSPRNVTAGAGL 448

Query: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513
            NDGQWH V F AK +   + +D D  +AV+    + + +G+ Y+FGG L   + S     
Sbjct: 449  NDGQWHSVSFSAKWSHMNVVVDDD--TAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP 506

Query: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573
               FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++CEHGG+CSQ+W
Sbjct: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566

Query: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633
            D+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLGP  VYCNMT 
Sbjct: 567  DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTA 626

Query: 634  DKVWTIVSHDLQMQTPVVGY-NPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKM 692
            D  WT+V H       + G  +    S     Y+A   Q+ A  + AE CEQ ++  C  
Sbjct: 627  DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGT 686

Query: 693  SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752
            +R  ++ DG+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W
Sbjct: 687  ARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEW 746

Query: 753  RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812
              D   LS K+HLPV+Q+V+ DT +  SEA  ++GPL C+GD+++WN+ASF   +SYLHF
Sbjct: 747  TSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHF 806

Query: 813  STFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVR 872
              F GE +AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+
Sbjct: 807  PAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQ 866

Query: 873  SPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQ 931
            SPTP ND+QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+GG A  Q+
Sbjct: 867  SPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR 926

Query: 932  GFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDC 991
            GFLGCIRSL++NGV LDLEERA VT G   GC+GHC++YG  C NGG+C E+  G +CDC
Sbjct: 927  GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDC 986

Query: 992  SNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEI 1051
            + +AYDG FC+ ++ A+F  G  + Y+FQ   T + +SSS V +          L +E I
Sbjct: 987  AFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL----YRDVTLTREMI 1042

Query: 1052 RFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQ 1111
              SF TT++P +LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ
Sbjct: 1043 TLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQ 1102

Query: 1112 PHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYN 1171
             H V I R E  + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +  
Sbjct: 1103 LHQVKINREEAVVMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1160

Query: 1172 TPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSATDP 1230
            T GFTGCLS V+F + APLKAALR +  S  V ++G +   + C A   + SP       
Sbjct: 1161 TSGFTGCLSAVRFGRAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELAPR 1219

Query: 1231 WHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHK 1290
                   S   D      +G+ + N   R+SA++GGVIAVVIF +LC     IR +++ +
Sbjct: 1220 LAGGAGRSGPVD------EGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR-IYQQR 1272

Query: 1291 GTYHTNEAKGAESAE 1305
                 NE+K ++  E
Sbjct: 1273 KLRKENESKVSKKEE 1287


>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score = 1145 bits (2961), Expect = 0.0
 Identities = 577/1321 (43%), Positives = 824/1321 (62%), Gaps = 76/1321 (5%)

Query: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
            CDE LV  L   +  +SS  S   +P +A+++   G  GWSP   D   WLQ+D   + +
Sbjct: 25   CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81

Query: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
            I A+ATQG ++S DWVT+Y +LY D   +W P++Q G+   F GN+N   VVRH+L    
Sbjct: 82   IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141

Query: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
             ARY+RIVPL WN  G+IGLR+ +YGC Y AD++ FDG   + YRF     ++L DV A 
Sbjct: 142  TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201

Query: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
            +FKT E +G++LH EG QGDY+TLEL+ A L+L ++LGS+ + P  GHT+V  G +L+D 
Sbjct: 202  SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261

Query: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
            HWH V ++R GR +N TLD  +Q F  NG+F+ L+LD E+  GG+  + + + + R NF+
Sbjct: 262  HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321

Query: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNAT-SYLEVPGRLNQD 393
            GC+E++ +N VNI DLA R+    +  G ++F C++P   P+ F    ++++VPG   + 
Sbjct: 322  GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381

Query: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453
              +VSF+FRTW+  GLL+FS   D LG+VE+ L+E +  V+++I Q+   ++  ++G  L
Sbjct: 382  RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQ--VNVSIAQSGRKKLQFAAGYRL 439

Query: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513
            NDG WHEV F+A+EN A+++ID  E + VR + PL ++TG  YFFGG     +       
Sbjct: 440  NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499

Query: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573
            Q +F GCM+L++VD QLVNL  V  R+ G +A V  D C I DRC PN CEH G+C Q+W
Sbjct: 500  QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559

Query: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633
            D F C C+ TGY G TCH  +Y+ SCEAY+  G+TS  + IDPDGSGPL P  VYC++ E
Sbjct: 560  DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619

Query: 634  DKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVY-SASMDQISAITDSAEYCEQYVSYFCKM 692
            ++ WT+V HD    T V G + E+  +  + Y +AS +++SA+ +++++CEQ++ + C  
Sbjct: 620  NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679

Query: 693  SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752
            SRLLNT  G PY++W+G+  E+H+YWGGS PGIQ+CACG++R+C DP  YCNCDAD  QW
Sbjct: 680  SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739

Query: 753  RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812
            R D G L++ DHLPV+QVV+GDT+R  SEA+  + PLRC GDRN WN  SF +  + L F
Sbjct: 740  RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISF-HTGAALRF 798

Query: 813  STFQGETSADISFYFKTLTPWGVFLENMG------KEDFIKLELKSATEVSFSFDVGNGP 866
               +   S D+SFYF+T  P GVFLENMG      +  ++++EL ++ +V F+FDVGNG 
Sbjct: 799  PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858

Query: 867  VEIVVRSPT-PLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVG 925
              + V S     NDD+WH V AE NVKQA L+VD  P  +R  P + +  +E    L+VG
Sbjct: 859  ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918

Query: 926  GAG-GQQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERY 984
             A   ++ F+GC+R++R+NGVTL+LE RA  + G    C+GHC      C +GG+C+ERY
Sbjct: 919  SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978

Query: 985  HGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAP------- 1037
              Y+CDC  TA+DG +CN D+G FFE G W+RYN Q+   +A    S + + P       
Sbjct: 979  SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038

Query: 1038 -----DQQNSHP---------------------------DLAQEEIRFSFSTTKAPCILL 1065
                 D     P                           ++  EE+ FSFST+ AP +LL
Sbjct: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098

Query: 1066 YISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIF 1125
            Y+SSF  D++AVL+K  G+LQ+RY LG    PY   +  R + +GQPHS+NITR  + +F
Sbjct: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156

Query: 1126 LKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFN 1185
            +++D++P          D+  +SPK+L+LG+V+ETG ID EI +YNTPGF+GCLS V+FN
Sbjct: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216

Query: 1186 QIAPLKAALR-----QTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSAS 1240
             +APLK   R         +  + +QGEL ESNCGA P  +S +    DPW+L       
Sbjct: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPELDPWYL------P 1270

Query: 1241 ADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKG 1300
             DFPY   +G          + ++G ++A ++  ++  LV       R+KG+YHTNE K 
Sbjct: 1271 PDFPYYHDEGWV--------AILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKA 1322

Query: 1301 A 1301
            A
Sbjct: 1323 A 1323


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score =  936 bits (2420), Expect = 0.0
 Identities = 443/892 (49%), Positives = 609/892 (68%), Gaps = 7/892 (0%)

Query: 35  CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
           CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 31  CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 95  ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
           ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 155 IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
            AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L Y    K +K ++DVI+L
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 215 NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
            FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 275 HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
           HWHSV+IE     +N T+D+   HF+  G+   LDL++EI+FGGI   G+  + +RK+F 
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330

Query: 335 GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393
           GC+E++ YNGV++T+LA++ K +   +GN+SFSC +P TVPV F ++ SYL +PG   +D
Sbjct: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390

Query: 394 LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453
             SV+FQFRTWN  G L+F       G+  + L + K  + +++ Q   S  ++++G+GL
Sbjct: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGK--LKLSLFQAGQSPRNVTAGAGL 448

Query: 454 NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513
           NDGQWH V F AK +   + +D D  +AV+    + + +G+ Y+FGG L   + S     
Sbjct: 449 NDGQWHSVSFSAKWSHMNVVVDDD--TAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP 506

Query: 514 QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573
              FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++CEHGG+CSQ+W
Sbjct: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566

Query: 574 DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633
           D+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLGP  VYCNMT 
Sbjct: 567 DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMT- 625

Query: 634 DKVWTIVSHDLQMQTPVVGY-NPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKM 692
           D  WT+V H       + G  +    S     Y+A   Q+ A  + AE CEQ ++  C  
Sbjct: 626 DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGT 685

Query: 693 SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752
           +R  ++ DG+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W
Sbjct: 686 ARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEW 745

Query: 753 RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812
             D   LS K+HLPV+Q+V+ DT +  SEA  ++GPL C+GD+++WN+ASF   +SYLHF
Sbjct: 746 TSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHF 805

Query: 813 STFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVR 872
             F GE +AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+
Sbjct: 806 PAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQ 865

Query: 873 SPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFV 924
           SPTP ND+QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+
Sbjct: 866 SPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917



 Score =  168 bits (426), Expect = 3e-41
 Identities = 111/303 (36%), Positives = 164/303 (54%), Gaps = 15/303 (4%)

Query: 1004 DVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCI 1063
            ++ A+F  G  + Y+FQ   T + +SSS V +          L +E I  SF TT++P +
Sbjct: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVT----LTREMITLSFRTTRSPSL 973

Query: 1064 LLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKT 1123
            LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ H V I R E  
Sbjct: 974  LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 1033

Query: 1124 IFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQ 1183
            + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +  T GFTGCLS V+
Sbjct: 1034 VMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVR 1091

Query: 1184 FNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSATDPWHLDHLDSASAD 1242
            F + APLKAALR +  S  V ++G +   + C A   + SP              S   D
Sbjct: 1092 FGRAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVD 1150

Query: 1243 FPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAE 1302
                  +G+ + N   R+SA++GGVIAVVIF +LC     IR +++ +     NE+K ++
Sbjct: 1151 ------EGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR-IYQQRKLRKENESKVSK 1203

Query: 1303 SAE 1305
              E
Sbjct: 1204 KEE 1206



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 56/221 (25%), Positives = 86/221 (38%), Gaps = 23/221 (10%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLEN---MGKEDFIKLELKSATEVSF 858
            +F +  SYL      GE    ++F F+T    G  L      G   F+ L LK       
Sbjct: 373  TFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLS 431

Query: 859  SFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVD---RLPQQIRKAPTEGHTR 915
             F  G  P  +   +   LND QWH V+        ++ VD    +   +      G T 
Sbjct: 432  LFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDT- 488

Query: 916  LELYSQLFVGGAGGQQ------GFLGCIRSLRMNGVTLD--LEERAKVTSGF---ISGCS 964
               Y    +G + G        GF GC+R + +    +D  L ++  + S     I  C 
Sbjct: 489  --YYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG 546

Query: 965  GHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDV 1005
                   + CE+GG+C + +  +SCDC  T Y G  C+  +
Sbjct: 547  ITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 944

 Score =  499 bits (1285), Expect = e-141
 Identities = 243/469 (51%), Positives = 325/469 (69%), Gaps = 12/469 (2%)

Query: 701  GSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLS 760
            G+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W  D   LS
Sbjct: 428  GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487

Query: 761  YKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETS 820
             K+HLPV+Q+V+ D  +  SEA  ++GPL C+GD+++WN+ASF   +SYLHF  F GE +
Sbjct: 488  QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547

Query: 821  ADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDD 880
            AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+SPTP ND+
Sbjct: 548  ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607

Query: 881  QWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQGFLGCIRS 939
            QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+GG A  Q+GFLGCIRS
Sbjct: 608  QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667

Query: 940  LRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGT 999
            L++NGV LDLEERA V  G   GC+GHC++YG  C NGG+C E+  G +CDC+ +AYDG 
Sbjct: 668  LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727

Query: 1000 FCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEEIRFSFST 1057
            FC+ ++ A+F  G  + Y+FQ   T + +SSS V +       H D  L +E I  SF T
Sbjct: 728  FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL------HRDVTLTREMITLSFRT 781

Query: 1058 TKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNI 1117
            T+ P +LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ H V I
Sbjct: 782  TRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKI 841

Query: 1118 TRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVI-ETGKIDQ 1165
             R E  + ++++   S    +  SS T FN+ KSL LGKV+  +G +D+
Sbjct: 842  NREEAVVMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDE 888



 Score =  162 bits (410), Expect = 2e-39
 Identities = 72/130 (55%), Positives = 92/130 (70%), Gaps = 2/130 (1%)

Query: 506 NNSSHSVLQP--SFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHC 563
           N+S      P   FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++C
Sbjct: 190 NSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYC 249

Query: 564 EHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLG 623
           EHGG+CSQ+WD+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLG
Sbjct: 250 EHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLG 309

Query: 624 PLKVYCNMTE 633
           P  VYCNMT+
Sbjct: 310 PFLVYCNMTD 319



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 29/242 (11%)

Query: 377 FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436
           F   TSYL  P    +    V F F+T   +G+     F +NLG  +    E +    + 
Sbjct: 530 FNTETSYLHFPAFHGELTADVCFFFKTTVSSGV-----FMENLGITDFIRIELRAPTEVT 584

Query: 437 IT---QTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDG--DEASAVRTNSPLQVK 491
            +        ++ + S +  ND QWH VR       A L +D    +      +  ++++
Sbjct: 585 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQ 644

Query: 492 TGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDM 551
              + F GG   +         Q  F GC++ +Q++   ++L E A   PG         
Sbjct: 645 LNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLEERATVMPGVEPG----- 690

Query: 552 CAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNY 611
           CA       + C +GG+C +      C C  + Y G  C N I      AY   G +  Y
Sbjct: 691 CAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI-----SAYFATGSSMTY 745

Query: 612 YW 613
           ++
Sbjct: 746 HF 747



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 42/147 (28%), Positives = 74/147 (50%), Gaps = 19/147 (12%)

Query: 216 FKTSESEGVILHGEGQQGDYITLELKK-AKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
           FKT+ S GV +   G   D+I +EL+   ++  S ++G+   GP     +V + +  +D+
Sbjct: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGN---GPC--EVTVQSPTPFNDN 607

Query: 275 HWHSVVIERQGRSINLTLD---RSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRK 331
            WH V  ER  +  +L +D   + MQ    +G    L L+ ++  GG       +++ ++
Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHV-RLQLNSQLFIGG-------TATRQR 659

Query: 332 NFKGCMESINYNGVNITDLARRKKLEP 358
            F GC+ S+  NGV + DL  R  + P
Sbjct: 660 GFLGCIRSLQLNGVAL-DLEERATVMP 685



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 932  GFLGCIRSLRMNGVTLD--LEERAKVTSGF---ISGCSGHCTSYGTNCENGGKCLERYHG 986
            GF GC+R + +    +D  L ++  + S     I  C        + CE+GG+C + +  
Sbjct: 202  GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261

Query: 987  YSCDCSNTAYDGTFCNKDV 1005
            +SCDC  T Y G  C+  +
Sbjct: 262  FSCDCLGTGYTGETCHSSL 280



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 1249 QGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAE 1305
            +G+ + N   R+SA+IGGVIAV IF +LC     IR +++ +     NE+K ++  E
Sbjct: 888  EGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIR-IYQQRKLRKENESKVSKKEE 943



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 15/140 (10%)

Query: 1050 EIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMAN 1109
            ++ F F TT +  + +     T DF+ + ++    +   +++G    P  + V      N
Sbjct: 549  DVCFFFKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNG--PCEVTVQSPTPFN 605

Query: 1110 -GQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIH 1168
              Q H V   R+ K   L++D  P      P+           LF+G      +      
Sbjct: 606  DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------ 659

Query: 1169 KYNTPGFTGCLSRVQFNQIA 1188
                 GF GC+  +Q N +A
Sbjct: 660  -----GFLGCIRSLQLNGVA 674


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  366 bits (940), Expect = e-101
 Identities = 165/321 (51%), Positives = 230/321 (71%)

Query: 35  CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94
           CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 31  CDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90

Query: 95  ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154
           ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150

Query: 155 IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214
            AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L Y    K +K ++DVI+L
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210

Query: 215 NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
            FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 211 KFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 275 HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334
           HWHSV+IE     +N T+D+   HF+  G+   LDL++EI+FGGIP  G+  + +RK+F 
Sbjct: 271 HWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTPGRSRAFTRKSFH 330

Query: 335 GCMESINYNGVNITDLARRKK 355
           GC+E++ YNGV++T+LA++ K
Sbjct: 331 GCLENLYYNGVDVTELAKKHK 351



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 41/146 (28%), Positives = 61/146 (41%), Gaps = 19/146 (13%)

Query: 823 ISFYFKTLTPWGVFLENMGKE-DFIKLELKSATEVSFSFDVGNGPVEIVVRSPTP----- 876
           IS  FK +   G+ L   G+  + I LEL     V F  + GN  +   +   T      
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFF-LNSGNAKLPSTIAPVTLTLGSL 266

Query: 877 LNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG--------AG 928
           L+D  WH V  E    Q +  VD+     +       + L+L  ++  GG        A 
Sbjct: 267 LDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDS--SNLDLNFEISFGGIPTPGRSRAF 324

Query: 929 GQQGFLGCIRSLRMNGVTLDLEERAK 954
            ++ F GC+ +L  NGV  D+ E AK
Sbjct: 325 TRKSFHGCLENLYYNGV--DVTELAK 348



 Score = 34.7 bits (78), Expect = 0.63
 Identities = 32/148 (21%), Positives = 63/148 (42%), Gaps = 11/148 (7%)

Query: 397 VSFQFRTWNPNGLLVFSHFADNLGN-VEIDLTESKVGVHINITQTKM----SQIDISSGS 451
           +S +F+    NG+L+  H     GN + ++L + K+   +N    K+    + + ++ GS
Sbjct: 208 ISLKFKAMQSNGILL--HREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGS 265

Query: 452 GLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHS 511
            L+D  WH V           T+D              +    +  FGG        S +
Sbjct: 266 LLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGI--PTPGRSRA 323

Query: 512 VLQPSFQGCMQLIQVDDQLVNLYEVAQR 539
             + SF GC++ +  +   V++ E+A++
Sbjct: 324 FTRKSFHGCLENLYYNG--VDVTELAKK 349


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  166 bits (421), Expect = 1e-40
 Identities = 159/602 (26%), Positives = 257/602 (42%), Gaps = 116/602 (19%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGK-EDFIKLELKSATEVSFSF 860
            +F   SSY+  +T Q  TS  + F FKT +  G+ L N G   DFI +EL     + + F
Sbjct: 908  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGY-LHYVF 966

Query: 861  DVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYS 920
            D+GNG   I   S  PLND+QWH V   R+   ++L   ++  +I    T G   L+L S
Sbjct: 967  DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1024

Query: 921  QLFVGGAG------------GQQGFLGCIRSLRMNGVTLDLEERAKVTSGFIS-GCSGHC 967
             L++GG               ++GF GC+ S+ +NG   DL   A   +G I  GC G  
Sbjct: 1025 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1084

Query: 968  TS-YGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA---FFEEGMWLRYNFQAPA 1023
            T+    +C N G CL+++ G+SCDCS T++ G  CN D G    F + G  + Y +    
Sbjct: 1085 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN-DPGTTYIFSKGGGQITYKW---- 1139

Query: 1024 TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYI--SSFTTDFLAVLVKP 1081
                             N  P    + +   FST +   +L+ +  SS   D+L + +  
Sbjct: 1140 ---------------PPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIH- 1183

Query: 1082 TGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSS 1141
             G + +++N+G   +   I+  +  + +G+ H V  TR      L++D +P +  +    
Sbjct: 1184 QGKIGVKFNVG--TDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGR 1241

Query: 1142 SDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLK-AALRQTNAS 1200
              T+FNS  ++ +G             K     F G LS + +N +  L  AA    N +
Sbjct: 1242 QLTIFNSQATIIIG------------GKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIA 1289

Query: 1201 --AHVHIQGEL-----VESNCGA------------------------SPLTLSPMSSATD 1229
               +V + GE+      ES   A                         P T  P+S  TD
Sbjct: 1290 IVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTD 1349

Query: 1230 ---------PWHLDHLD-------------SASADFPYNPGQGQAIRNGVNRNSAIIGGV 1267
                     P   + +D              A    PY PG  + IR   +    ++ G+
Sbjct: 1350 DILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPY-PGSAEVIRESSSTTGMVV-GI 1407

Query: 1268 IAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKG--AESAESADAAIMNNDPNFTETIDES 1325
            +A     IL  L  + +Y  R +G+YH +E++   + SA+S  A +    P+  ++ +++
Sbjct: 1408 VAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKN 1467

Query: 1326 KK 1327
            KK
Sbjct: 1468 KK 1469



 Score =  115 bits (289), Expect = 2e-25
 Identities = 105/437 (24%), Positives = 197/437 (45%), Gaps = 25/437 (5%)

Query: 165  DWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGV 224
            D +G G +G       C   A V+++DG + +  +     M T  + ++L F++  + G+
Sbjct: 701  DCSGTGYLGR-----SCEREATVLSYDGSMFMKIQLP-VVMHTEAEDVSLRFRSQRAYGI 754

Query: 225  ILHGEGQQG-DYITLELKKAKLVLSLNLGSNQLG--PIYGHTSVMTGSLLDDHHWHSVVI 281
            ++    +   D + LEL   ++ L++NL   ++      G  ++  G  L+D+ WH+V +
Sbjct: 755  LMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRV 814

Query: 282  ERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESIN 341
             R+G+S+ LT+D   Q        D+  L++     GI    +  SS   NF G ++S+ 
Sbjct: 815  VRRGKSLKLTVD-DQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLT 873

Query: 342  YNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNA-TSYLEVPGRLNQDLFSVSFQ 400
            +NG+   DL +   ++   + N  F        PV F   +SY+ +          + FQ
Sbjct: 874  FNGMAYIDLCKNGDIDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQ 932

Query: 401  FRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHE 460
            F+T + +GL++++   D    + ++L +  +    ++     + I  SS   LND QWH 
Sbjct: 933  FKTTSLDGLILYNS-GDGNDFIVVELVKGYLHYVFDLGNGA-NLIKGSSNKPLNDNQWHN 990

Query: 461  VRFLAKENFAILTIDGDEASAVR-TNSPLQVKTGEKYFFGGFLNQMNNSSHSVL--QPSF 517
            V  ++++   + T+  D     + T     +      + GG   +   S   ++  +  F
Sbjct: 991  V-MISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1049

Query: 518  QGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDM-C-AIIDRCVPNHCEHGGKCSQTWDS 575
            QGC+  + ++ +L +L   A      F N  I+  C      C  + C + G C Q WD 
Sbjct: 1050 QGCLASVDLNGRLPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDG 1104

Query: 576  FKCTCDETGYSGATCHN 592
            F C C  T +SG  C++
Sbjct: 1105 FSCDCSMTSFSGPLCND 1121



 Score =  114 bits (284), Expect = 8e-25
 Identities = 102/442 (23%), Positives = 183/442 (41%), Gaps = 50/442 (11%)

Query: 187 VINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLV 246
           +  F G     Y      +++  D I L+FKT +  G++LH  G+  DY+ L LK   + 
Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 341

Query: 247 LSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRS--------INLTLDRSMQH 298
           L +NLGS   G        + G   +D+ WH V + R  R         + +++D  +  
Sbjct: 342 LVINLGS---GAFEALVEPVNGKF-NDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397

Query: 299 FR-TNGEFDYLDLDYEITFGGIPFSGK-PSSSSRKNFKGCMESINYNG----VNITDLAR 352
              T  ++  L  D     GG P +   P S    NF GC++ + Y      + ++ LA+
Sbjct: 398 TGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 457

Query: 353 RKKLEPSNVGNLSFSCVEPYTV-PVFFNAT-SYLEVPGRLNQDLFSVSFQFRTWNPNGLL 410
           +   +    G ++F C    T+ P+ F    S++ +P    +   S+SF FRT  PNGL+
Sbjct: 458 QGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLI 517

Query: 411 VFSHFADNLGNVEIDLTESKVGVHINITQTKMSQID------ISSGSG----------LN 454
           +FSH             ++K    I +    +  +D      +  GSG          +N
Sbjct: 518 LFSHGKPR------HQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVN 571

Query: 455 DGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSH---- 510
           DG+W+ V F        ++++              +   ++ + GG              
Sbjct: 572 DGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEV 631

Query: 511 --SVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGK 568
             ++L   + GC++ + +D Q  ++ ++A+ +  +    S         C+ N C++ G 
Sbjct: 632 WTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSK-ETAKPCLSNPCKNNGM 690

Query: 569 CSQTWDSFKCTCDETGYSGATC 590
           C   W+ + C C  TGY G +C
Sbjct: 691 CRDGWNRYVCDCSGTGYLGRSC 712



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 112/465 (24%), Positives = 193/465 (41%), Gaps = 73/465 (15%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKE--------------DFIK 847
            +F  P S++    +  + +  ISF F+T  P G+ L + GK               DF  
Sbjct: 483  TFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFA 542

Query: 848  LELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRK 907
            +E+     +    D+G+G ++I       +ND +W+ V  +R+ +  ++ V+ L      
Sbjct: 543  IEMLDG-HLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTISVNTLRTPYT- 599

Query: 908  APTEGHTRLELYSQLFVGGAGGQQ----------------GFLGCIRSLRMNGVTLDLEE 951
            AP E    L+L  +L++GG    +                G++GCIR L ++G + D+ +
Sbjct: 600  APGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQ 658

Query: 952  RAKV--TSGFISGCSGHCTS--YGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA 1007
             A+V  T+G    CS           C+N G C + ++ Y CDCS T Y G  C ++   
Sbjct: 659  MAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV 718

Query: 1008 FFEEGMWLRYNFQAPA---TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCIL 1064
               +G  +    Q P    T A D S R  +    Q ++  L     R S  T +     
Sbjct: 719  LSYDGS-MFMKIQLPVVMHTEAEDVSLRFRS----QRAYGILMATTSRDSADTLR----- 768

Query: 1065 LYISSFTTDFLAVLVKPTGSLQ-IRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKT 1123
                    +  A  VK T +L  IR N   ++ P  +   + N+ + + H+V + R  K+
Sbjct: 769  -------LELDAGRVKLTVNLDCIRINCNSSKGPETLFAGY-NLNDNEWHTVRVVRRGKS 820

Query: 1124 IFLKLDHYPSVSYHLPSSSDTL-FNSPKSLFLGKVIETGKIDQEIHKYNTP-GFTGCLSR 1181
            + L +D   +++  +      L F++         IETG I +  +  + P  F G L  
Sbjct: 821  LKLTVDDQQAMTGQMAGDHTRLEFHN---------IETGIITERRYLSSVPSNFIGHLQS 871

Query: 1182 VQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSS 1226
            + FN +A +   L +     +  +       N  A P+T    SS
Sbjct: 872  LTFNGMAYID--LCKNGDIDYCELNARFGFRNIIADPVTFKTKSS 914



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 72/337 (21%), Positives = 136/337 (40%), Gaps = 79/337 (23%)

Query: 212 IALNFKTSESEGVILHGEGQ-------------QGDYITLELKKAKLVLSLNLGSNQLGP 258
           I+ +F+T+E  G+IL   G+             + D+  +E+    L L L++GS     
Sbjct: 504 ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSG---- 559

Query: 259 IYGHTSVMTGSLL---DDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEIT 315
                ++   +LL   +D  W+ V  +R GRS  ++++     +   GE + LDLD E+ 
Sbjct: 560 -----TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELY 614

Query: 316 FGGIP---------------------------------------------FSGKPSSSSR 330
            GG+P                                              +G   S S+
Sbjct: 615 LGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSK 674

Query: 331 KNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNATSYLEV--PG 388
           +  K C+ +   N     D   R   + S  G L  SC    TV + ++ + ++++  P 
Sbjct: 675 ETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV-LSYDGSMFMKIQLPV 733

Query: 389 RLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINI------TQTKM 442
            ++ +   VS +FR+    G+L+ +   D+   + ++L   +V + +N+        +  
Sbjct: 734 VMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSK 793

Query: 443 SQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEA 479
               + +G  LND +WH VR + +     LT+D  +A
Sbjct: 794 GPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 76/344 (22%), Positives = 141/344 (40%), Gaps = 40/344 (11%)

Query: 809  YLHFSTFQGETSADISFYFKTLTPWGVFL--ENMGKEDFIKLELKSATEVSFSFDVGNGP 866
            +  F  +     +++SF  KT +  G+ L  ++ G  DF++L L     +  SF +    
Sbjct: 40   WTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAE 99

Query: 867  VEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG 926
               ++ + TP+ND  WH V   R  +  +L +D++  +  +  ++    + ++S LFVGG
Sbjct: 100  PATLL-ADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSK-RRDMTVFSGLFVGG 157

Query: 927  ----------------AGGQQGFLGCIRSLRMNGVTLDLEERAKV-------TSGFISGC 963
                               ++ F G IR +R+N   +   +  +V        SG  S C
Sbjct: 158  LPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPC 217

Query: 964  SGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPA 1023
                   G  C NGG C        CDCS T + G  C+++      EG  L +      
Sbjct: 218  EAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNV--EG--LAHLMMGDQ 273

Query: 1024 TNARDSSSRVDNAPDQQNSHPDLAQ-------EEIRFSFSTTKAPCILLYISSFTTDFLA 1076
              ++     +      +    DL+Q       +EI  SF T +   ++L+    + D++ 
Sbjct: 274  GKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK-SADYVN 332

Query: 1077 VLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRH 1120
            + +K  G++ +  NLG       ++  +    +   H V +TR+
Sbjct: 333  LALK-NGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRN 375



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 77/306 (25%), Positives = 134/306 (43%), Gaps = 55/306 (17%)

Query: 216  FKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHH 275
            FKT+  +G+IL+  G   D+I +EL K  L    +LG N    I G ++      L+D+ 
Sbjct: 933  FKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLG-NGANLIKGSSN----KPLNDNQ 987

Query: 276  WHSVVIERQGRSIN-LTLDRSMQHFRTNGEFDYLDLDYEITFGGIP---FSGKPSS-SSR 330
            WH+V+I R   +++ + +D  +    T G  + LDL  ++  GG+    +   P    ++
Sbjct: 988  WHNVMISRDTSNLHTVKIDTKITTQITAGARN-LDLKSDLYIGGVAKETYKSLPKLVHAK 1046

Query: 331  KNFKGCMESINYNGVNITDLARR-------------------KKLEPSNVG--------- 362
            + F+GC+ S++ NG  + DL                      ++   SN G         
Sbjct: 1047 EGFQGCLASVDLNG-RLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGF 1105

Query: 363  -----NLSFS---CVEPYTVPVFFNA---TSYLEVPG-RLNQDLFSVSFQFRTWNPNGLL 410
                   SFS   C +P T  +F       +Y   P  R +     ++  F T     +L
Sbjct: 1106 SCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVL 1165

Query: 411  VFSHFADNLGN-VEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENF 469
            V    +  LG+ +E+ + + K+GV  N+    ++  +  S + +NDG++H VRF      
Sbjct: 1166 VRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEE--SNAIINDGKYHVVRFTRSGGN 1223

Query: 470  AILTID 475
            A L +D
Sbjct: 1224 ATLQVD 1229



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 34/162 (20%)

Query: 819 TSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPT-PL 877
           +S +I+  FKTL   G+ L      D++ L LK+   VS   ++G+G  E +V       
Sbjct: 304 SSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKF 362

Query: 878 NDDQWHRVTAERNVKQAS--------LQVDRLPQQIRKAPTEGHTRLELYSQL------F 923
           ND+ WH V   RN++Q S        + VD +        T G+T+ E Y+ L      +
Sbjct: 363 NDNAWHDVKVTRNLRQHSGIGHAMVTISVDGI------LTTTGYTQ-EDYTMLGSDDFFY 415

Query: 924 VGGAGG---------QQGFLGCIRSL--RMNGVTLDLEERAK 954
           VGG+              F+GC++ +  + N V L+L   AK
Sbjct: 416 VGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 457



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 39/185 (21%), Positives = 81/185 (43%), Gaps = 18/185 (9%)

Query: 202  NKKMKTLKDVIALNFKTSESEGVILHGEGQQG--DYITLELKKAKLVLSLNLGSNQLGPI 259
            N +  T  D +A+ F T + E V++  +   G  DY+ L + + K+ +  N+G++ +   
Sbjct: 1142 NDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIA-- 1199

Query: 260  YGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDR--SMQHFRTNGEFDYLDLDYEITFG 317
                   + ++++D  +H V   R G +  L +D    ++ +    +    +    I  G
Sbjct: 1200 ----IEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG 1255

Query: 318  GIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVF 377
            G    G+P       F+G +  + YNG+ + ++A       + VGN+      P ++   
Sbjct: 1256 GKE-QGQP-------FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTE 1307

Query: 378  FNATS 382
              AT+
Sbjct: 1308 STATA 1312



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 52/221 (23%), Positives = 88/221 (39%), Gaps = 18/221 (8%)

Query: 397 VSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDG 456
           +SFQ +T +  GL+++         +E+ LT     + ++ +        + + + +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGG-RLQLSFSIFCAEPATLLADTPVNDG 112

Query: 457 QWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTG-EKYFFGGFLNQMNNSSHSVLQP 515
            WH VR   +     L ID  EA  V   S  +  T     F GG   ++  ++  +   
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLA 172

Query: 516 S------FQGCMQLIQVDDQLVNLYEVAQRK-----PGSFANVSIDMCAIIDRCVPNHCE 564
           S      F+G ++ ++V+   V   +  + K     P S        C   +      C 
Sbjct: 173 SVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG---SPCEAGEEGEGGVCL 229

Query: 565 HGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHL 605
           +GG CS   D   C C  TG+ G  C  S  + + E   HL
Sbjct: 230 NGGVCSVVDDQAVCDCSRTGFRGKDC--SQEDNNVEGLAHL 268


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  166 bits (420), Expect = 1e-40
 Identities = 113/304 (37%), Positives = 162/304 (53%), Gaps = 19/304 (6%)

Query: 1005 VGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEEIRFSFSTTKAPC 1062
            + A+F  G  + Y+FQ   T + +SSS V +       H D  L +E I  SF TT+ P 
Sbjct: 3    ISAYFATGSSMTYHFQEHYTLSENSSSLVSSL------HRDVTLTREMITLSFRTTRTPS 56

Query: 1063 ILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEK 1122
            +LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ H V I R E 
Sbjct: 57   LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 116

Query: 1123 TIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRV 1182
             + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +  T GFTGCLS V
Sbjct: 117  VVMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAV 174

Query: 1183 QFNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSATDPWHLDHLDSASA 1241
            +F   APLKAALR +  S  V ++G +   + C A   + SP              S   
Sbjct: 175  RFGCAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPV 233

Query: 1242 DFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGA 1301
            D      +G+ + N   R+SA+IGGVIAV IF +LC     IR +++ +     NE+K +
Sbjct: 234  D------EGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIR-IYQQRKLRKENESKVS 286

Query: 1302 ESAE 1305
            +  E
Sbjct: 287  KKEE 290


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  159 bits (401), Expect = 2e-38
 Identities = 159/620 (25%), Positives = 265/620 (42%), Gaps = 122/620 (19%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGK-EDFIKLELKSATEVSFSF 860
            +F   SSY+  +T Q  TS  + F FKT +  G+ L N G   DFI +EL     + + F
Sbjct: 948  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGY-LHYVF 1006

Query: 861  DVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYS 920
            D+GNG   I   S  PLND+QWH V   R+   ++L   ++  +I    T G   L+L S
Sbjct: 1007 DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1064

Query: 921  QLFVGGAG------------GQQGFLGCIRSLRMNGVTLDLEERAKVTSGFIS-GCSGHC 967
             L++GG               ++GF GC+ S+ +NG   DL   A   +G I  GC G  
Sbjct: 1065 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1124

Query: 968  TS-YGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA---FFEEGMWLRYNFQAPA 1023
            T+    +C N G CL+++ G+SCDCS T++ G  CN D G    F + G  + Y +    
Sbjct: 1125 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN-DPGTTYIFSKGGGQITYKW---- 1179

Query: 1024 TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYI--SSFTTDFLAVLVKP 1081
                             N  P    + +   FST +   +L+ +  SS   D+L + +  
Sbjct: 1180 ---------------PPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIH- 1223

Query: 1082 TGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSS 1141
             G + +++N+G   +   I+  +  + +G+ H V  TR      L++D +P +  +   +
Sbjct: 1224 QGKIGVKFNVG--TDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGN 1281

Query: 1142 SD----TLFNSPKSLFLGKVIETGKID--QEIHKYNTPG------------FTGCLSRVQ 1183
            +D     +        LG+V++   +D  +++  +N+              F G LS + 
Sbjct: 1282 NDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLY 1341

Query: 1184 FNQIAPLK-AALRQTNAS--AHVHIQGEL-----VESNCGA------------------- 1216
            +N +  L  AA    N +   +V + GE+      ES   A                   
Sbjct: 1342 YNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATS 1401

Query: 1217 -----SPLTLSPMSSATD---------PWHLDHLD-------------SASADFPYNPGQ 1249
                  P T  P+S  TD         P   + +D              A    PY PG 
Sbjct: 1402 TARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPY-PGS 1460

Query: 1250 GQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKG--AESAESA 1307
             + IR   +    ++ G++A     IL  L  + +Y  R +G+YH +E++   + SA+S 
Sbjct: 1461 AEVIRESSSTTGMVV-GIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSN 1519

Query: 1308 DAAIMNNDPNFTETIDESKK 1327
             A +    P+  ++ +++KK
Sbjct: 1520 GAVVKEKQPSSAKSSNKNKK 1539



 Score =  115 bits (289), Expect = 2e-25
 Identities = 105/437 (24%), Positives = 197/437 (45%), Gaps = 25/437 (5%)

Query: 165  DWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGV 224
            D +G G +G       C   A V+++DG + +  +     M T  + ++L F++  + G+
Sbjct: 741  DCSGTGYLGR-----SCEREATVLSYDGSMFMKIQLP-VVMHTEAEDVSLRFRSQRAYGI 794

Query: 225  ILHGEGQQG-DYITLELKKAKLVLSLNLGSNQLG--PIYGHTSVMTGSLLDDHHWHSVVI 281
            ++    +   D + LEL   ++ L++NL   ++      G  ++  G  L+D+ WH+V +
Sbjct: 795  LMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRV 854

Query: 282  ERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESIN 341
             R+G+S+ LT+D   Q        D+  L++     GI    +  SS   NF G ++S+ 
Sbjct: 855  VRRGKSLKLTVD-DQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLT 913

Query: 342  YNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNA-TSYLEVPGRLNQDLFSVSFQ 400
            +NG+   DL +   ++   + N  F        PV F   +SY+ +          + FQ
Sbjct: 914  FNGMAYIDLCKNGDIDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQ 972

Query: 401  FRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHE 460
            F+T + +GL++++   D    + ++L +  +    ++     + I  SS   LND QWH 
Sbjct: 973  FKTTSLDGLILYNS-GDGNDFIVVELVKGYLHYVFDLGNGA-NLIKGSSNKPLNDNQWHN 1030

Query: 461  VRFLAKENFAILTIDGDEASAVR-TNSPLQVKTGEKYFFGGFLNQMNNSSHSVL--QPSF 517
            V  ++++   + T+  D     + T     +      + GG   +   S   ++  +  F
Sbjct: 1031 V-MISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGF 1089

Query: 518  QGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDM-C-AIIDRCVPNHCEHGGKCSQTWDS 575
            QGC+  + ++ +L +L   A      F N  I+  C      C  + C + G C Q WD 
Sbjct: 1090 QGCLASVDLNGRLPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDG 1144

Query: 576  FKCTCDETGYSGATCHN 592
            F C C  T +SG  C++
Sbjct: 1145 FSCDCSMTSFSGPLCND 1161



 Score =  112 bits (281), Expect = 2e-24
 Identities = 103/449 (22%), Positives = 184/449 (40%), Gaps = 57/449 (12%)

Query: 187 VINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLV 246
           +  F G     Y      +++  D I L+FKT +  G++LH  G+  DY+ L LK   + 
Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 374

Query: 247 LSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGR---------------SINLT 291
           L +NLGS   G        + G   +D+ WH V + R  R               S+ ++
Sbjct: 375 LVINLGS---GAFEALVEPVNGKF-NDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430

Query: 292 LDRSMQHFR-TNGEFDYLDLDYEITFGGIPFSGK-PSSSSRKNFKGCMESINYNG----V 345
           +D  +     T  ++  L  D     GG P +   P S    NF GC++ + Y      +
Sbjct: 431 VDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRL 490

Query: 346 NITDLARRKKLEPSNVGNLSFSCVEPYTV-PVFFNAT-SYLEVPGRLNQDLFSVSFQFRT 403
            ++ LA++   +    G ++F C    T+ P+ F    S++ +P    +   S+SF FRT
Sbjct: 491 ELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRT 550

Query: 404 WNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQID------ISSGSG----- 452
             PNGL++FSH             ++K    I +    +  +D      +  GSG     
Sbjct: 551 TEPNGLILFSHGKPR------HQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIK 604

Query: 453 -----LNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNN 507
                +NDG+W+ V F        ++++              +   ++ + GG       
Sbjct: 605 ALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAG 664

Query: 508 SSH------SVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPN 561
                    ++L   + GC++ + +D Q  ++ ++A+ +  +    S         C+ N
Sbjct: 665 LVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSK-ETAKPCLSN 723

Query: 562 HCEHGGKCSQTWDSFKCTCDETGYSGATC 590
            C++ G C   W+ + C C  TGY G +C
Sbjct: 724 PCKNNGMCRDGWNRYVCDCSGTGYLGRSC 752



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 112/465 (24%), Positives = 193/465 (41%), Gaps = 73/465 (15%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKE--------------DFIK 847
            +F  P S++    +  + +  ISF F+T  P G+ L + GK               DF  
Sbjct: 523  TFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFA 582

Query: 848  LELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRK 907
            +E+     +    D+G+G ++I       +ND +W+ V  +R+ +  ++ V+ L      
Sbjct: 583  IEMLDG-HLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTISVNTLRTPYT- 639

Query: 908  APTEGHTRLELYSQLFVGGAGGQQ----------------GFLGCIRSLRMNGVTLDLEE 951
            AP E    L+L  +L++GG    +                G++GCIR L ++G + D+ +
Sbjct: 640  APGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQ 698

Query: 952  RAKV--TSGFISGCSGHCTS--YGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA 1007
             A+V  T+G    CS           C+N G C + ++ Y CDCS T Y G  C ++   
Sbjct: 699  MAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV 758

Query: 1008 FFEEGMWLRYNFQAPA---TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCIL 1064
               +G  +    Q P    T A D S R  +    Q ++  L     R S  T +     
Sbjct: 759  LSYDGS-MFMKIQLPVVMHTEAEDVSLRFRS----QRAYGILMATTSRDSADTLR----- 808

Query: 1065 LYISSFTTDFLAVLVKPTGSLQ-IRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKT 1123
                    +  A  VK T +L  IR N   ++ P  +   + N+ + + H+V + R  K+
Sbjct: 809  -------LELDAGRVKLTVNLDCIRINCNSSKGPETLFAGY-NLNDNEWHTVRVVRRGKS 860

Query: 1124 IFLKLDHYPSVSYHLPSSSDTL-FNSPKSLFLGKVIETGKIDQEIHKYNTP-GFTGCLSR 1181
            + L +D   +++  +      L F++         IETG I +  +  + P  F G L  
Sbjct: 861  LKLTVDDQQAMTGQMAGDHTRLEFHN---------IETGIITERRYLSSVPSNFIGHLQS 911

Query: 1182 VQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSS 1226
            + FN +A +   L +     +  +       N  A P+T    SS
Sbjct: 912  LTFNGMAYID--LCKNGDIDYCELNARFGFRNIIADPVTFKTKSS 954



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 72/337 (21%), Positives = 136/337 (40%), Gaps = 79/337 (23%)

Query: 212 IALNFKTSESEGVILHGEGQ-------------QGDYITLELKKAKLVLSLNLGSNQLGP 258
           I+ +F+T+E  G+IL   G+             + D+  +E+    L L L++GS     
Sbjct: 544 ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSG---- 599

Query: 259 IYGHTSVMTGSLL---DDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEIT 315
                ++   +LL   +D  W+ V  +R GRS  ++++     +   GE + LDLD E+ 
Sbjct: 600 -----TIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELY 654

Query: 316 FGGIP---------------------------------------------FSGKPSSSSR 330
            GG+P                                              +G   S S+
Sbjct: 655 LGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSK 714

Query: 331 KNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNATSYLEV--PG 388
           +  K C+ +   N     D   R   + S  G L  SC    TV + ++ + ++++  P 
Sbjct: 715 ETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV-LSYDGSMFMKIQLPV 773

Query: 389 RLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINI------TQTKM 442
            ++ +   VS +FR+    G+L+ +   D+   + ++L   +V + +N+        +  
Sbjct: 774 VMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSK 833

Query: 443 SQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEA 479
               + +G  LND +WH VR + +     LT+D  +A
Sbjct: 834 GPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 27/222 (12%)

Query: 809  YLHFSTFQGETSADISFYFKTLTPWGVFL--ENMGKEDFIKLELKSATEVSFSFDVGNGP 866
            +  F  +     +++SF  KT +  G+ L  ++ G  DF++L L     +  SF +    
Sbjct: 40   WTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAE 99

Query: 867  VEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG 926
               ++ + TP+ND  WH V   R  +  +L +D++  +  +  ++    + ++S LFVGG
Sbjct: 100  PATLL-ADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSK-RRDMTVFSGLFVGG 157

Query: 927  ----------------AGGQQGFLGCIRSLRMNGVTLDLEERAKV-------TSGFISGC 963
                               ++ F G IR +R+N   +   +  +V        SG  S C
Sbjct: 158  LPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPC 217

Query: 964  SGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDV 1005
                   G  C NGG C        CDCS T + G  C++++
Sbjct: 218  EAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 77/306 (25%), Positives = 134/306 (43%), Gaps = 55/306 (17%)

Query: 216  FKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHH 275
            FKT+  +G+IL+  G   D+I +EL K  L    +LG N    I G ++      L+D+ 
Sbjct: 973  FKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLG-NGANLIKGSSN----KPLNDNQ 1027

Query: 276  WHSVVIERQGRSIN-LTLDRSMQHFRTNGEFDYLDLDYEITFGGIP---FSGKPSS-SSR 330
            WH+V+I R   +++ + +D  +    T G  + LDL  ++  GG+    +   P    ++
Sbjct: 1028 WHNVMISRDTSNLHTVKIDTKITTQITAGARN-LDLKSDLYIGGVAKETYKSLPKLVHAK 1086

Query: 331  KNFKGCMESINYNGVNITDLARR-------------------KKLEPSNVG--------- 362
            + F+GC+ S++ NG  + DL                      ++   SN G         
Sbjct: 1087 EGFQGCLASVDLNG-RLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGF 1145

Query: 363  -----NLSFS---CVEPYTVPVFFNA---TSYLEVPG-RLNQDLFSVSFQFRTWNPNGLL 410
                   SFS   C +P T  +F       +Y   P  R +     ++  F T     +L
Sbjct: 1146 SCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVL 1205

Query: 411  VFSHFADNLGN-VEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENF 469
            V    +  LG+ +E+ + + K+GV  N+    ++  +  S + +NDG++H VRF      
Sbjct: 1206 VRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEE--SNAIINDGKYHVVRFTRSGGN 1263

Query: 470  AILTID 475
            A L +D
Sbjct: 1264 ATLQVD 1269



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 29/163 (17%)

Query: 819 TSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPT-PL 877
           +S +I+  FKTL   G+ L      D++ L LK+   VS   ++G+G  E +V       
Sbjct: 337 SSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKF 395

Query: 878 NDDQWHRVTAERNVKQAS----LQVDRLPQQIRKA-----PTEGHTRLELYSQL------ 922
           ND+ WH V   RN++Q S      V++L   +  +      T G+T+ E Y+ L      
Sbjct: 396 NDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQ-EDYTMLGSDDFF 454

Query: 923 FVGGAGG---------QQGFLGCIRSL--RMNGVTLDLEERAK 954
           +VGG+              F+GC++ +  + N V L+L   AK
Sbjct: 455 YVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 497



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 16/210 (7%)

Query: 397 VSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDG 456
           +SFQ +T +  GL+++         +E+ LT     + ++ +        + + + +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFDDEGFCDFLELILTRGG-RLQLSFSIFCAEPATLLADTPVNDG 112

Query: 457 QWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTG-EKYFFGGFLNQMNNSSHSVLQP 515
            WH VR   +     L ID  EA  V   S  +  T     F GG   ++  ++  +   
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLA 172

Query: 516 S------FQGCMQLIQVDDQLVNLYEVAQRK-----PGSFANVSIDMCAIIDRCVPNHCE 564
           S      F+G ++ ++V+   V   +  + K     P S        C   +      C 
Sbjct: 173 SVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG---SPCEAGEEGEGGVCL 229

Query: 565 HGGKCSQTWDSFKCTCDETGYSGATCHNSI 594
           +GG CS   D   C C  TG+ G  C   I
Sbjct: 230 NGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 43/210 (20%), Positives = 82/210 (39%), Gaps = 38/210 (18%)

Query: 202  NKKMKTLKDVIALNFKTSESEGVILHGEGQQG--DYITLELKKAKLVLSLNLGSNQLGPI 259
            N +  T  D +A+ F T + E V++  +   G  DY+ L + + K+ +  N+G++ +   
Sbjct: 1182 NDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIA-- 1239

Query: 260  YGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLD---------------------RSMQH 298
                   + ++++D  +H V   R G +  L +D                     R    
Sbjct: 1240 ----IEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIP 1295

Query: 299  FRTNGEFD--YLDLDYEITF----GGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLAR 352
            +R     D   LD   ++T       I   GK        F+G +  + YNG+ + ++A 
Sbjct: 1296 YRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQP---FQGQLSGLYYNGLKVLNMAA 1352

Query: 353  RKKLEPSNVGNLSFSCVEPYTVPVFFNATS 382
                  + VGN+      P ++     AT+
Sbjct: 1353 ENDANIAIVGNVRLVGEVPSSMTTESTATA 1382


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  154 bits (388), Expect = 7e-37
 Identities = 161/574 (28%), Positives = 244/574 (42%), Gaps = 110/574 (19%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGK-EDFIKLELKSATEVSFSF 860
            +F   SSYL  +T Q  TS  + F FKT +P G  L N G   DFI +EL     + + F
Sbjct: 501  TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGY-IHYVF 559

Query: 861  DVGNGPVEIVVRSPTPLNDDQWHRVTAER-NVKQASLQVDRLPQQIRKAPTEGHTRLELY 919
            D+GNGP  I   S  PLND+QWH V   R N    SL+VD    ++      G   L+L 
Sbjct: 560  DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDT---KVVTQVINGAKNLDLK 616

Query: 920  SQLFVGG------------AGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFIS-GCSGH 966
              L++ G               + GF GC+ S+ +NG   DL   A   SG I  GC G 
Sbjct: 617  GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGP 676

Query: 967  CTS-YGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA---FFEEGMWLRYNFQAP 1022
             T+    +C N G C++++ G++CDCS T+Y G  CN D GA   F + G  + Y + A 
Sbjct: 677  STTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN-DPGATYIFGKSGGLILYTWPA- 734

Query: 1023 ATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSF--TTDFLAVLVK 1080
                              N  P    + +   FSTT    IL+ I S     DFL + ++
Sbjct: 735  ------------------NDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIE 776

Query: 1081 PTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPS 1140
              G + + +N+G      +I  +   + +G+ H V  TR+     L++D++P V+ H P+
Sbjct: 777  -QGKIGVVFNIGTV--DISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWP-VNEHYPT 832

Query: 1141 SSD-TLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQT-- 1197
                T+FN+   + +G   + G++           F G LS + ++ +  L  A      
Sbjct: 833  GRQLTIFNTQAQIAIGGK-DKGRL-----------FQGQLSGLYYDGLKVLNMAAENNPN 880

Query: 1198 -NASAHVHIQGELVESNCGASPLTLSPMSSAT-----------------------DPWHL 1233
               +  V + GE V S  G +  T  P   +T                        P   
Sbjct: 881  IKINGSVRLVGE-VPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSD 939

Query: 1234 DHLDSASA-----DF---------PYNPG--QGQAIRNGVNRNSAIIGGVIAVVIFTILC 1277
            D + SA       DF         P  PG  +       +  +S+  G V+ +V    LC
Sbjct: 940  DLVSSAECSSDDEDFVECEPSTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALC 999

Query: 1278 TLVFL---IRYMFRHKGTYHTNEAKG--AESAES 1306
             L+ L    +Y  R +G+Y  +E +   + SA+S
Sbjct: 1000 ILILLYAMYKYRNRDEGSYQVDETRNYISNSAQS 1033



 Score =  108 bits (271), Expect = 3e-23
 Identities = 99/426 (23%), Positives = 181/426 (42%), Gaps = 22/426 (5%)

Query: 180 GCSYW-------ADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQ 232
           G  YW       A ++++DG + +        M T  + ++  F +  + G+++    + 
Sbjct: 298 GTGYWGRTCEREASILSYDGSMYMKI-IMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRD 356

Query: 233 G-DYITLELKKAKLVLSLNLGSNQLG--PIYGHTSVMTGSLLDDHHWHSVVIERQGRSIN 289
             D + LEL   ++ L +NL   ++      G  ++  G  L+D+ WH+V + R+G+S+ 
Sbjct: 357 SADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLK 416

Query: 290 LTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITD 349
           LT+D  +      G  D+  L++     GI    +  S    +F G ++S+ +NG+   D
Sbjct: 417 LTVDDDVAEGTMVG--DHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYID 474

Query: 350 LARRKKLEPSNVGNLSFSCVEPYTVPVFFNA-TSYLEVPGRLNQDLFSVSFQFRTWNPNG 408
           L +   ++   +    F        PV F   +SYL +          + FQF+T +P+G
Sbjct: 475 LCKNGDIDYCEL-KARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDG 533

Query: 409 LLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLA-KE 467
            ++F+   D    + ++L +  +    ++     + I  +S   LND QWH V       
Sbjct: 534 FILFNS-GDGNDFIAVELVKGYIHYVFDLGNGP-NVIKGNSDRPLNDNQWHNVVITRDNS 591

Query: 468 NFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL-QPSFQGCMQLIQV 526
           N   L +D    + V   +      G+ Y  G      +N    V  +  FQGC+  + +
Sbjct: 592 NTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDL 651

Query: 527 DDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYS 586
           + +L +L   A  + G               C  + C + G C Q W+ F C C  T YS
Sbjct: 652 NGRLPDLINDALHRSGQIERGCEGPSTT---CQEDSCANQGVCMQQWEGFTCDCSMTSYS 708

Query: 587 GATCHN 592
           G  C++
Sbjct: 709 GNQCND 714



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 83/363 (22%), Positives = 150/363 (41%), Gaps = 81/363 (22%)

Query: 186 DVINFD---GHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVIL--HGEGQQG------- 233
           D INF+    ++ LP ++  K+M +    I+ +F+T+E  G+IL  HG+ Q+        
Sbjct: 74  DPINFETPEAYISLP-KWNTKRMGS----ISFDFRTTEPNGLILFTHGKPQERKDARSQK 128

Query: 234 ----DYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSIN 289
               D+  +EL    L L L++GS  +          T    +D  W+ V I+R GRS  
Sbjct: 129 NTKVDFFAVELLDGNLYLLLDMGSGTI------KVKATQKKANDGEWYHVDIQRDGRSGT 182

Query: 290 LTLDRSMQHFRTNGEFDYLDLDYEITFGGIP----------------------------- 320
           ++++     F  +GE + LDL+ ++  GG+P                             
Sbjct: 183 ISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLF 242

Query: 321 ----------------FSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNL 364
                            +G  SS SR + K C      N     D   R   + +  G  
Sbjct: 243 IDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYW 302

Query: 365 SFSCVEPYTVPVFFNATSYLEV--PGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNV 422
             +C    ++ + ++ + Y+++  P  ++ +   VSF+F +    GLLV +   D+   +
Sbjct: 303 GRTCEREASI-LSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTL 361

Query: 423 EIDLTESKVGVHINI------TQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDG 476
            ++L   +V + +N+        +      + +G  LND +WH VR + +     LT+D 
Sbjct: 362 RLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD 421

Query: 477 DEA 479
           D A
Sbjct: 422 DVA 424



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 70/308 (22%), Positives = 122/308 (39%), Gaps = 46/308 (14%)

Query: 317 GGIPFSGK-PSSSSRKNFKGCMESINYNG----VNITDLARRKKLEPSNVGNLSFSCVEP 371
           GG P +   P S    NF GC++ + Y      + ++ LAR    +    G + F C   
Sbjct: 11  GGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENV 70

Query: 372 YTV-PVFFNAT-SYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSH--------------- 414
            T+ P+ F    +Y+ +P    + + S+SF FRT  PNGL++F+H               
Sbjct: 71  ATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNT 130

Query: 415 ----FADNL--GNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKEN 468
               FA  L  GN+ + L      + +  TQ K            NDG+W+ V       
Sbjct: 131 KVDFFAVELLDGNLYLLLDMGSGTIKVKATQKK-----------ANDGEWYHVDIQRDGR 179

Query: 469 FAILTIDGDEASAVRTNSPLQVKTGEKYFFGGF------LNQMNNSSHSVLQPSFQGCMQ 522
              ++++        +     +      + GG       L        ++L   + GC++
Sbjct: 180 SGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIR 239

Query: 523 LIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDE 582
            + +D +  N+ ++A+ +  +    S    +   +C    C++   C   W+ F C C  
Sbjct: 240 DLFIDGRSKNIRQLAEMQNAAGVKSSCSRMS-AKQCDSYPCKNNAVCKDGWNRFICDCTG 298

Query: 583 TGYSGATC 590
           TGY G TC
Sbjct: 299 TGYWGRTC 306



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 98/471 (20%), Positives = 182/471 (38%), Gaps = 86/471 (18%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKE--------------DFIK 847
            +F  P +Y+    +  +    ISF F+T  P G+ L   GK               DF  
Sbjct: 77   NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136

Query: 848  LELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRK 907
            +EL     +    D+G+G +++   +    ND +W+ V  +R+ +  ++ V+      R+
Sbjct: 137  VELLDGN-LYLLLDMGSGTIKVKA-TQKKANDGEWYHVDIQRDGRSGTISVNS-----RR 189

Query: 908  AP--TEGHTR-LELYSQLFVGGAGGQQ----------------GFLGCIRSLRMNGVTLD 948
             P    G +  L+L   +++GG    +                G++GCIR L ++G + +
Sbjct: 190  TPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKN 249

Query: 949  LEERAKV--TSGFISGCSG----HCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCN 1002
            + + A++   +G  S CS      C SY   C+N   C + ++ + CDC+ T Y G  C 
Sbjct: 250  IRQLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCE 307

Query: 1003 KDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPC 1062
            ++      +G            +                       E++ F F + +A  
Sbjct: 308  REASILSYDGSMYMKIIMPMVMHTE--------------------AEDVSFRFMSQRAYG 347

Query: 1063 ILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQP------HSVN 1116
            +L+  +S  +     L    G +++  NL   R   N       +  GQ       H+V 
Sbjct: 348  LLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVR 407

Query: 1117 ITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTP-GF 1175
            + R  K++ L +D   +    +   +   F++         IETG + ++ +    P  F
Sbjct: 408  VVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHN---------IETGIMTEKRYISVVPSSF 458

Query: 1176 TGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSS 1226
             G L  + FN +  L   L +     +  ++      N  A P+T    SS
Sbjct: 459  IGHLQSLMFNGL--LYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSS 507



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 84/314 (26%), Positives = 135/314 (42%), Gaps = 71/314 (22%)

Query: 216 FKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSL---LD 272
           FKT+  +G IL   G   D+I +EL K  +    +LG+   GP     +V+ G+    L+
Sbjct: 526 FKTTSPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGN---GP-----NVIKGNSDRPLN 577

Query: 273 DHHWHSVVIERQGRSIN-LTLDRSMQHFRTNGEFDYLDLDYEITFGGIP---FSGKPSS- 327
           D+ WH+VVI R   + + L +D  +     NG  + LDL  ++   G+    +S  P   
Sbjct: 578 DNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKN-LDLKGDLYMAGLAQGMYSNLPKLV 636

Query: 328 SSRKNFKGCMESINYNGVNITDLA-----RRKKLE-----PSNV---------------- 361
           +SR  F+GC+ S++ NG  + DL      R  ++E     PS                  
Sbjct: 637 ASRDGFQGCLASVDLNG-RLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQW 695

Query: 362 -------GNLSFS---CVEPYTVPVFFNATSYLEVPGRLNQ------DLFSVSFQFRTWN 405
                     S+S   C +P    +F  +   +      N       D  +V F   T  
Sbjct: 696 EGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFS--TTV 753

Query: 406 PNGLLVFSHFADNLGN-VEIDLTESKVGVHINITQTKMSQIDIS---SGSGLNDGQWHEV 461
            +G+LV    A  LG+ +++ + + K+GV  NI       +DIS     + +NDG++H V
Sbjct: 754 KDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNI-----GTVDISIKEERTPVNDGKYHVV 808

Query: 462 RFLAKENFAILTID 475
           RF      A L +D
Sbjct: 809 RFTRNGGNATLQVD 822



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 32/154 (20%), Positives = 69/154 (44%), Gaps = 18/154 (11%)

Query: 202 NKKMKTLKDVIALNFKTSESEGVILHGEGQQ--GDYITLELKKAKLVLSLNLGSNQLGPI 259
           N +  T  D +A+ F T+  +G+++  +     GD++ L +++ K+ +  N+G+  +   
Sbjct: 735 NDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIK 794

Query: 260 YGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDR--SMQHFRTNGEFDYLDLDYEITFG 317
              T V      +D  +H V   R G +  L +D     +H+ T  +    +   +I  G
Sbjct: 795 EERTPV------NDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIG 848

Query: 318 GIPFSGKPSSSSRKNFKGCMESINYNGVNITDLA 351
           G            + F+G +  + Y+G+ + ++A
Sbjct: 849 G--------KDKGRLFQGQLSGLYYDGLKVLNMA 874


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  136 bits (343), Expect = 1e-31
 Identities = 104/374 (27%), Positives = 173/374 (46%), Gaps = 46/374 (12%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGK-EDFIKLELKSATEVSFSF 860
            +F + SSYL  +T Q   S  + F FKT  P G+ L N G   DFI +EL     + + F
Sbjct: 881  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGY-IHYVF 939

Query: 861  DVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYS 920
            D+GNGP  +   S  P+ND+QWH V   R+    ++   ++  +     + G   L+L  
Sbjct: 940  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 997

Query: 921  QLFVGG------------AGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFIS-GCSGHC 967
            +L++GG               + GF GC+ S+ +NG   DL   A    G +  GC G  
Sbjct: 998  ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1057

Query: 968  TSYGT-NCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA---FFEEGMWLRYNFQAPA 1023
            T+    +C N G CL+++ G++CDC+ T+Y G  CN D G    F + G  + Y +    
Sbjct: 1058 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN-DPGTTYIFGKGGALITYTW---- 1112

Query: 1024 TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT--TDFLAVLVKP 1081
                             N  P    + +   FST +   +L+ + S +   D+L + +  
Sbjct: 1113 ---------------PPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-D 1156

Query: 1082 TGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSS 1141
             G++ + +N+G   +   ID  +  +++G+ H V  TR      L++D +P    +    
Sbjct: 1157 QGTVGVIFNVG--TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGR 1214

Query: 1142 SDTLFNSPKSLFLG 1155
              T+FNS  ++ +G
Sbjct: 1215 QLTIFNSQAAIKIG 1228



 Score =  112 bits (279), Expect = 3e-24
 Identities = 106/422 (25%), Positives = 188/422 (44%), Gaps = 32/422 (7%)

Query: 181  CSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQG-DYITLE 239
            C   A V+++DG + +     N  M T  + ++L F +  + G+++    ++  D + LE
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNA-MHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 240  LKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHF 299
            L   ++ L++NLG        G  ++  G  L+D+ WH+V + R+G+S+ L++D      
Sbjct: 754  LDGGQMKLTVNLGK-------GPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 300  RTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPS 359
            +  G   ++ L++     GI    +  S    NF G +  + +NG    D  +   +   
Sbjct: 807  QMAGA--HMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYC 864

Query: 360  NVGNLSFSCVEPYTVPVFFNA-TSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADN 418
             + N  F        PV F + +SYL +          + FQF+T  P+GLL+F     N
Sbjct: 865  EL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLF-----N 918

Query: 419  LGN----VEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTI 474
             GN    + I+L +  +    ++     S +  +S   +ND QWH V  ++++   + T+
Sbjct: 919  SGNGNDFIVIELVKGYIHYVFDLGNGP-SLMKGNSDKPVNDNQWHNV-VVSRDPGNVHTL 976

Query: 475  DGDEASAVRTNSP---LQVKTGEKYFFGGFLNQMNNSSHSVL-QPSFQGCMQLIQVDDQL 530
              D  +  + ++    L +K GE Y  G   N  +N    V  +  FQGC+  + ++ +L
Sbjct: 977  KIDSRTVTQHSNGARNLDLK-GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRL 1035

Query: 531  VNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATC 590
             +L   A  + G    V          C    C + G C Q WD F C C  T Y G  C
Sbjct: 1036 PDLIADALHRIGQ---VERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVC 1092

Query: 591  HN 592
            ++
Sbjct: 1093 ND 1094



 Score =  107 bits (268), Expect = 6e-23
 Identities = 105/448 (23%), Positives = 185/448 (41%), Gaps = 61/448 (13%)

Query: 187 VINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLV 246
           V  F G+    Y   +  +++  D I L F+T +  G++LH  G+  DY+ L LK   + 
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 323

Query: 247 LSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRS--------INLTLDRSMQH 298
           L +NLGS   G        + G   +D+ WH V + R  R         + +++D  +  
Sbjct: 324 LVINLGS---GAFEALVEPVNGKF-NDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT 379

Query: 299 FR-TNGEFDYLDLDYEITFGGIPFSGK-PSSSSRKNFKGCMESINYNG----VNITDLAR 352
              T  ++  L  D     GG P +   P S    NF GC++ + Y      + ++ LA+
Sbjct: 380 TGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAK 439

Query: 353 RKKLEPSNVGNLSFSCVEPYTV-PVFFNAT-SYLEVPGRLNQDLFSVSFQFRTWNPNGLL 410
               +    G+LSF C +   + PV F +  +++ +P    +   S+S  FRT  PNGLL
Sbjct: 440 EGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLL 499

Query: 411 VFS-------------------HFADNL--GNVEIDLTESKVGVHINITQTKMSQIDISS 449
           +FS                   +FA  L  G++ + L     G+ +  +  K+       
Sbjct: 500 LFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKV------- 552

Query: 450 GSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGF-------L 502
               NDG+W  V F        ++++      + T     +    + + GG        L
Sbjct: 553 ----NDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDL 608

Query: 503 NQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNH 562
                   + L+  + GC++ + +D +  +L  +A+ + G+           + +C    
Sbjct: 609 PLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQ-GAVGVAPFCSRETLKQCASAP 667

Query: 563 CEHGGKCSQTWDSFKCTCDETGYSGATC 590
           C +GG C + W+ F C C  TG+ G  C
Sbjct: 668 CRNGGVCREGWNRFICDCIGTGFLGRVC 695



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 88/391 (22%), Positives = 165/391 (42%), Gaps = 83/391 (21%)

Query: 789  LRCQGDRNY-------WNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMG 841
            ++ QGD ++        +  +F +P +++    +  + +  IS  F+T  P G+ L + G
Sbjct: 445  MKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQG 504

Query: 842  KE--------------DFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTA 887
            +               D+  +EL     +    D+G+G +++   S   +ND +W  V  
Sbjct: 505  RRAGGGAGSHSSAQRADYFAMELLDG-HLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDF 562

Query: 888  ERNVKQASLQVDRLPQQIRKAP---TEGHTRLELYSQLFVGGA--GGQ------------ 930
            +R+ ++ S+ V+      R  P   T     L+L S+L++GG   GG+            
Sbjct: 563  QRDGRKGSISVNS-----RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTA 617

Query: 931  ---QGFLGCIRSLRMNGVTLDLEERAKVTS--GFISGCSGH----CTSYGTNCENGGKCL 981
                G++GC+R L ++G + DL   A+     G    CS      C S    C NGG C 
Sbjct: 618  ALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCAS--APCRNGGVCR 675

Query: 982  ERYHGYSCDCSNTAYDGTFCNKDVGAFFEEG-MWLRYNF-QAPATNARDSSSRVDNAPDQ 1039
            E ++ + CDC  T + G  C ++      +G M+++     A  T A D S R       
Sbjct: 676  EGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLR------- 728

Query: 1040 QNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYN 1099
                           F + +A  +++  +S  +     L    G +++  NLG  + P  
Sbjct: 729  ---------------FMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLG--KGPET 771

Query: 1100 IDVDHRNMANGQPHSVNITRHEKTIFLKLDH 1130
            +   H+ + + + H+V + R  K++ L +D+
Sbjct: 772  LFAGHK-LNDNEWHTVRVVRRGKSLQLSVDN 801



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 103/469 (21%), Positives = 182/469 (38%), Gaps = 44/469 (9%)

Query: 806  PSSYLHFSTFQGETSA-DISFYFKTLTPWGV--FLENMGKEDFIKLELKSAT-EVSFSFD 861
            P  +  ++ + G  S+ ++SF  +T     +  +L++ G  DF++L L      + F+  
Sbjct: 35   PGQWARYARWAGAASSGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLS 94

Query: 862  VGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTR-LELYS 920
                     ++  TP+ DD+WH V   R+ ++ +L VD    + R A      R +++ S
Sbjct: 95   CAE---PATLQLDTPVADDRWHMVLLTRDARRTALAVD---GEARAAEVRSKRREMQVAS 148

Query: 921  QLFVGGAGGQQGFLGCIRS-------LRMNGVTLDLEER--AKVTSGFISGCSGH--CTS 969
             LFVGG            S        R     L L ER  A + S  + G +    C  
Sbjct: 149  DLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAP 208

Query: 970  YGTNCENGGKCLERYHG-YSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARD 1028
                C NGG C     G   CDCS+T + G FC+++     E    L  N +        
Sbjct: 209  ARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHP-MEGPAHLTLNSEGKEEFVAT 267

Query: 1029 SSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIR 1088
                     D  ++    + +EI  +F T +   ++L+    + D++ + +K +G++ + 
Sbjct: 268  FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGK-SADYVNLSLK-SGAVWLV 325

Query: 1089 YNLGGTREPYNIDVDHRNMANGQPHSVNITRH--------EKTIFLKLDHYPSVSYHLPS 1140
             NLG       ++  +    +   H V +TR+           + + +D   + + +   
Sbjct: 326  INLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGY-TQ 384

Query: 1141 SSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQF-NQIAPLKAALRQTNA 1199
               T+  S    ++G    T  +       N   F GCL  V + N    L+ +      
Sbjct: 385  EDYTMLGSDDFFYIGGSPNTADLPGSPVSNN---FMGCLKDVVYKNNDFKLELSRLAKEG 441

Query: 1200 SAHVHIQGEL---VESNCGASPLTL-SPMSSATDP-WHLDHLDSASADF 1243
               + +QG+L    E      P+T  SP +    P W      S S DF
Sbjct: 442  DPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF 490



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 99/425 (23%), Positives = 166/425 (39%), Gaps = 71/425 (16%)

Query: 822  DISFYFKTLTPWGVFLENMGKE--DFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLND 879
            D+S  F +   +G+ +    +E  D ++LEL    ++  + ++G GP  +       LND
Sbjct: 724  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGG-QMKLTVNLGKGPETLFAGHK--LND 780

Query: 880  DQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRS 939
            ++WH V   R  K   L VD +  + + A    H RLE ++     G   ++ F+  + S
Sbjct: 781  NEWHTVRVVRRGKSLQLSVDNVTVEGQMA--GAHMRLEFHN--IETGIMTERRFISVVPS 836

Query: 940  LRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGT 999
              +               G +SG   +   Y   C++G                   D T
Sbjct: 837  NFI---------------GHLSGLVFNGQPYMDQCKDG-------------------DIT 862

Query: 1000 FCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTK 1059
            +C  ++ A F     LR     P T  +  SS +  A  Q       A   + F F TT 
Sbjct: 863  YC--ELNARF----GLRAIVADPVT-FKSRSSYLALATLQA-----YASMHLFFQFKTTA 910

Query: 1060 APCILLYISSFTTDFLAV-LVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNIT 1118
               +LL+ S    DF+ + LVK  G +   ++LG        + D + + + Q H+V ++
Sbjct: 911  PDGLLLFNSGNGNDFIVIELVK--GYIHYVFDLGNGPSLMKGNSD-KPVNDNQWHNVVVS 967

Query: 1119 RHEKTIF-LKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTG 1177
            R    +  LK+D   +V+ H  S+     +    L++G + +    +      +  GF G
Sbjct: 968  RDPGNVHTLKIDS-RTVTQH--SNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQG 1024

Query: 1178 CLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLD 1237
            CL+ V  N   P   A         +H  G+ VE  C     T +  S A     L   D
Sbjct: 1025 CLASVDLNGRLPDLIA-------DALHRIGQ-VERGCDGPSTTCTEESCANQGVCLQQWD 1076

Query: 1238 SASAD 1242
              + D
Sbjct: 1077 GFTCD 1081



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 41/201 (20%), Positives = 81/201 (40%), Gaps = 19/201 (9%)

Query: 397 VSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDG 456
           +SF  RT     LL++     +   +E+ L + ++ +   ++  + + + + +   + D 
Sbjct: 53  LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTP--VADD 110

Query: 457 QWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSV---- 512
           +WH V          L +DG+  +A   +   +++     F GG    +  S+ ++    
Sbjct: 111 RWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVK 170

Query: 513 LQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVP--NHCEHGGKCS 570
            +P F+G          L NL ++ +R P    +  +        C P  N C +GG C+
Sbjct: 171 YEPPFRGL---------LANL-KLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCT 220

Query: 571 -QTWDSFKCTCDETGYSGATC 590
                   C C  TG+ G  C
Sbjct: 221 VLAPGEVGCDCSHTGFGGKFC 241



 Score = 37.4 bits (85), Expect = 0.097
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 1235 HLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLI---RYMFRHKG 1291
            HL +A+   P   G   A+   +  +S+  G V+ +V    LC L+ L    +Y  R +G
Sbjct: 1538 HLPTANPTGPGERGPPGAVEV-IRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEG 1596

Query: 1292 TYHTNEAKG--AESAESADAAIMNNDPNFTETIDESKK 1327
            +Y  ++++   + SA+S  A +    P   +T  ++KK
Sbjct: 1597 SYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKK 1634



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 4/106 (3%)

Query: 841  GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPL-NDDQWHRVTAERNVKQASLQVD 899
            G  D+++L +   T V   F+VG    +I +  P  + +D ++H V   R+   A+LQVD
Sbjct: 1146 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202

Query: 900  RLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGV 945
              P   R       T     + + +GG    + F G +  L  NG+
Sbjct: 1203 SWPVNERYPAGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGL 1248


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  130 bits (328), Expect = 6e-30
 Identities = 99/351 (28%), Positives = 163/351 (46%), Gaps = 46/351 (13%)

Query: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGK-EDFIKLELKSATEVSFSF 860
            +F + SSYL  +T Q   S  + F FKT  P G+ L N G   DFI +EL     + + F
Sbjct: 921  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGY-IHYVF 979

Query: 861  DVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYS 920
            D+GNGP  +   S  P+ND+QWH V   R+    ++   ++  +     + G   L+L  
Sbjct: 980  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 1037

Query: 921  QLFVGG------------AGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFIS-GCSGHC 967
            +L++GG               + GF GC+ S+ +NG   DL   A    G +  GC G  
Sbjct: 1038 ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1097

Query: 968  TSYGT-NCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGA---FFEEGMWLRYNFQAPA 1023
            T+    +C N G CL+++ G++CDC+ T+Y G  CN D G    F + G  + Y +    
Sbjct: 1098 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN-DPGTTYIFGKGGALITYTW---- 1152

Query: 1024 TNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT--TDFLAVLVKP 1081
                             N  P    + +   FST +   +L+ + S +   D+L + +  
Sbjct: 1153 ---------------PPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-D 1196

Query: 1082 TGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYP 1132
             G++ + +N+G   +   ID  +  +++G+ H V  TR      L++D +P
Sbjct: 1197 QGTVGVIFNVG--TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWP 1245



 Score =  114 bits (284), Expect = 8e-25
 Identities = 107/424 (25%), Positives = 191/424 (45%), Gaps = 27/424 (6%)

Query: 181  CSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQG-DYITLE 239
            C   A V+++DG + +     N  M T  + ++L F +  + G+++    ++  D + LE
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNA-MHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 240  LKKAKLVLSLNLGSNQLG--PIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQ 297
            L   ++ L++NL   ++G  P  G  ++  G  L+D+ WH+V + R+G+S+ L++D    
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTV 844

Query: 298  HFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLE 357
              +  G   ++ L++     GI    +  S    NF G +  + +NG    D  +   + 
Sbjct: 845  EGQMAGA--HMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDIT 902

Query: 358  PSNVGNLSFSCVEPYTVPVFFNA-TSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFA 416
               + N  F        PV F + +SYL +          + FQF+T  P+GLL+F    
Sbjct: 903  YCEL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLF---- 957

Query: 417  DNLGN----VEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAIL 472
             N GN    + I+L +  +    ++     S +  +S   +ND QWH V  ++++   + 
Sbjct: 958  -NSGNGNDFIVIELVKGYIHYVFDLGNGP-SLMKGNSDKPVNDNQWHNV-VVSRDPGNVH 1014

Query: 473  TIDGDEASAVRTNSP---LQVKTGEKYFFGGFLNQMNNSSHSVL-QPSFQGCMQLIQVDD 528
            T+  D  +  + ++    L +K GE Y  G   N  +N    V  +  FQGC+  + ++ 
Sbjct: 1015 TLKIDSRTVTQHSNGARNLDLK-GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNG 1073

Query: 529  QLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGA 588
            +L +L   A  + G    V          C    C + G C Q WD F C C  T Y G 
Sbjct: 1074 RLPDLIADALHRIGQ---VERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGP 1130

Query: 589  TCHN 592
             C++
Sbjct: 1131 VCND 1134



 Score =  105 bits (261), Expect = 4e-22
 Identities = 105/455 (23%), Positives = 185/455 (40%), Gaps = 68/455 (14%)

Query: 187 VINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLV 246
           V  F G+    Y   +  +++  D I L F+T +  G++LH  G+  DY+ L LK   + 
Sbjct: 289 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 347

Query: 247 LSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRS---------------INLT 291
           L +NLGS   G        + G   +D+ WH V + R  R                + ++
Sbjct: 348 LVINLGS---GAFEALVEPVNGKF-NDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTIS 403

Query: 292 LDRSMQHFR-TNGEFDYLDLDYEITFGGIPFSGK-PSSSSRKNFKGCMESINYNG----V 345
           +D  +     T  ++  L  D     GG P +   P S    NF GC++ + Y      +
Sbjct: 404 VDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKL 463

Query: 346 NITDLARRKKLEPSNVGNLSFSCVEPYTV-PVFFNAT-SYLEVPGRLNQDLFSVSFQFRT 403
            ++ LA+    +    G+LSF C +   + PV F +  +++ +P    +   S+S  FRT
Sbjct: 464 ELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRT 523

Query: 404 WNPNGLLVFS-------------------HFADNL--GNVEIDLTESKVGVHINITQTKM 442
             PNGLL+FS                   +FA  L  G++ + L     G+ +  +  K+
Sbjct: 524 TEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKV 583

Query: 443 SQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGF- 501
                      NDG+W  V F        ++++      + T     +    + + GG  
Sbjct: 584 -----------NDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLP 632

Query: 502 ------LNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAII 555
                 L        + L+  + GC++ + +D +  +L  +A+ + G+           +
Sbjct: 633 EGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQ-GAVGVAPFCSRETL 691

Query: 556 DRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATC 590
            +C    C +GG C + W+ F C C  TG+ G  C
Sbjct: 692 KQCASAPCRNGGVCREGWNRFICDCIGTGFLGRVC 726



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 87/392 (22%), Positives = 163/392 (41%), Gaps = 76/392 (19%)

Query: 789  LRCQGDRNY-------WNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMG 841
            ++ QGD ++        +  +F +P +++    +  + +  IS  F+T  P G+ L + G
Sbjct: 476  MKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQG 535

Query: 842  KE--------------DFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTA 887
            +               D+  +EL     +    D+G+G +++   S   +ND +W  V  
Sbjct: 536  RRAGGGAGSHSSAQRADYFAMELLDG-HLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDF 593

Query: 888  ERNVKQASLQVDRLPQQIRKAP---TEGHTRLELYSQLFVGGA--GGQ------------ 930
            +R+ ++ S+ V+      R  P   T     L+L S+L++GG   GG+            
Sbjct: 594  QRDGRKGSISVNS-----RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTA 648

Query: 931  ---QGFLGCIRSLRMNGVTLDLEERAKVTS--GFISGCSGH----CTSYGTNCENGGKCL 981
                G++GC+R L ++G + DL   A+     G    CS      C S    C NGG C 
Sbjct: 649  ALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCAS--APCRNGGVCR 706

Query: 982  ERYHGYSCDCSNTAYDGTFCNKDVGAFFEEG-MWLRYNF-QAPATNARDSSSRVDNAPDQ 1039
            E ++ + CDC  T + G  C ++      +G M+++     A  T A D S R       
Sbjct: 707  EGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRF------ 760

Query: 1040 QNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQ-IRYNLGGTREPY 1098
                  ++Q       +TT          +   +     +K T +L  +R     ++ P 
Sbjct: 761  ------MSQRAYGLMMATTSRES----ADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPE 810

Query: 1099 NIDVDHRNMANGQPHSVNITRHEKTIFLKLDH 1130
             +   H+ + + + H+V + R  K++ L +D+
Sbjct: 811  TLFAGHK-LNDNEWHTVRVVRRGKSLQLSVDN 841



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 110/498 (22%), Positives = 189/498 (37%), Gaps = 71/498 (14%)

Query: 806  PSSYLHFSTFQGETSA-DISFYFKTLTPWGV--FLENMGKEDFIKLELKSAT-EVSFSFD 861
            P  +  ++ + G  S+ ++SF  +T     +  +L++ G  DF++L L      + F+  
Sbjct: 35   PGQWARYARWAGAASSGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLS 94

Query: 862  VGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTR-LELYS 920
                     ++  TP+ DD+WH V   R+ ++ +L VD    + R A      R +++ S
Sbjct: 95   CAE---PATLQLDTPVADDRWHMVLLTRDARRTALAVD---GEARAAEVRSKRREMQVAS 148

Query: 921  QLFVGGAGGQQGFLGCIRS-------LRMNGVTLDLEER--AKVTSGFISGCSGH--CTS 969
             LFVGG            S        R     L L ER  A + S  + G +    C  
Sbjct: 149  DLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAP 208

Query: 970  YGTNCENGGKCLERYHG-YSCDCSNTAYDGTFC---------------NKDVGA-FFEEG 1012
                C NGG C     G   CDCS+T + G FC               N +VG+  F EG
Sbjct: 209  ARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEG 268

Query: 1013 MWLR---YNFQAPATNARDSSSRVDN----APDQQNSHPDLAQEEIRFSFSTTKAPCILL 1065
               R    +   P     +  +          D  ++    + +EI  +F T +   ++L
Sbjct: 269  GAGRGGAGDVHQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLML 328

Query: 1066 YISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEK--- 1122
            +    + D++ + +K +G++ +  NLG       ++  +    +   H V +TR+ +   
Sbjct: 329  HTGK-SADYVNLSLK-SGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHA 386

Query: 1123 ----TIFLKLDHYPSVSYH-------LPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYN 1171
                 +  KL +  ++S               T+  S    ++G    T  +       N
Sbjct: 387  GIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNN 446

Query: 1172 TPGFTGCLSRVQF-NQIAPLKAALRQTNASAHVHIQGEL---VESNCGASPLTL-SPMSS 1226
               F GCL  V + N    L+ +         + +QG+L    E      P+T  SP + 
Sbjct: 447  ---FMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAF 503

Query: 1227 ATDP-WHLDHLDSASADF 1243
               P W      S S DF
Sbjct: 504  VALPRWSAKRTGSISLDF 521



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 41/201 (20%), Positives = 81/201 (40%), Gaps = 19/201 (9%)

Query: 397 VSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDG 456
           +SF  RT     LL++     +   +E+ L + ++ +   ++  + + + + +   + D 
Sbjct: 53  LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTP--VADD 110

Query: 457 QWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSV---- 512
           +WH V          L +DG+  +A   +   +++     F GG    +  S+ ++    
Sbjct: 111 RWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVK 170

Query: 513 LQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVP--NHCEHGGKCS 570
            +P F+G          L NL ++ +R P    +  +        C P  N C +GG C+
Sbjct: 171 YEPPFRGL---------LANL-KLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCT 220

Query: 571 -QTWDSFKCTCDETGYSGATC 590
                   C C  TG+ G  C
Sbjct: 221 VLAPGEVGCDCSHTGFGGKFC 241



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 100/431 (23%), Positives = 168/431 (38%), Gaps = 74/431 (17%)

Query: 822  DISFYFKTLTPWGVFLENMGKE--DFIKLELKSAT-EVSFSFD---VGNGPVE--IVVRS 873
            D+S  F +   +G+ +    +E  D ++LEL     +++ + D   VG  P +    + +
Sbjct: 755  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFA 814

Query: 874  PTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGF 933
               LND++WH V   R  K   L VD +  + + A    H RLE ++     G   ++ F
Sbjct: 815  GHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMA--GAHMRLEFHN--IETGIMTERRF 870

Query: 934  LGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSN 993
            +  + S  +               G +SG   +   Y   C++G                
Sbjct: 871  ISVVPSNFI---------------GHLSGLVFNGQPYMDQCKDG---------------- 899

Query: 994  TAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRF 1053
               D T+C  ++ A F     LR     P T  +  SS +  A  Q       A   + F
Sbjct: 900  ---DITYC--ELNARF----GLRAIVADPVT-FKSRSSYLALATLQA-----YASMHLFF 944

Query: 1054 SFSTTKAPCILLYISSFTTDFLAV-LVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQP 1112
             F TT    +LL+ S    DF+ + LVK  G +   ++LG        + D + + + Q 
Sbjct: 945  QFKTTAPDGLLLFNSGNGNDFIVIELVK--GYIHYVFDLGNGPSLMKGNSD-KPVNDNQW 1001

Query: 1113 HSVNITRHEKTIF-LKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYN 1171
            H+V ++R    +  LK+D   +V+ H  S+     +    L++G + +    +      +
Sbjct: 1002 HNVVVSRDPGNVHTLKIDS-RTVTQH--SNGARNLDLKGELYIGGLSKNMFSNLPKLVAS 1058

Query: 1172 TPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPW 1231
              GF GCL+ V  N   P   A         +H  G+ VE  C     T +  S A    
Sbjct: 1059 RDGFQGCLASVDLNGRLPDLIA-------DALHRIGQ-VERGCDGPSTTCTEESCANQGV 1110

Query: 1232 HLDHLDSASAD 1242
             L   D  + D
Sbjct: 1111 CLQQWDGFTCD 1121



 Score = 37.4 bits (85), Expect = 0.097
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 1235 HLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLI---RYMFRHKG 1291
            HL +A+   P   G   A+   +  +S+  G V+ +V    LC L+ L    +Y  R +G
Sbjct: 1608 HLPTANPTGPGERGPPGAVEV-IRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEG 1666

Query: 1292 TYHTNEAKG--AESAESADAAIMNNDPNFTETIDESKK 1327
            +Y  ++++   + SA+S  A +    P   +T  ++KK
Sbjct: 1667 SYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKK 1704


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 56/160 (35%), Positives = 89/160 (55%), Gaps = 15/160 (9%)

Query: 35  CDEPLV---SGLPHVAFSSSSSISG------SYSPGYAKINKRGGAGGWSPSDSDHYQWL 85
           C  PL    + +P    ++SSS         S++P YA+++K+G    W      + QWL
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289

Query: 86  QVDFGNRKQISAIATQG--RYSSSDWVTQYRMLYSDTGRNWKPYH--QDGNIWAFPGNIN 141
           QVD G+ K+++ I TQG   + S  +V  Y++ YS+   NW  Y   + G+   FPGN +
Sbjct: 290 QVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWD 349

Query: 142 SDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
           +    ++  + PI+ARYVRI+P+ W+   RI LR+E+ GC
Sbjct: 350 NHSHKKNLFETPILARYVRILPVAWH--NRIALRLELLGC 387



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 18/176 (10%)

Query: 20  SCLC-RAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGS----------YSPGYAKINKR 68
           +C C + +       KC EPL  GL +   ++S   + S          + P  A++N+ 
Sbjct: 54  TCTCLKGYAGNHCETKCVEPL--GLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRA 111

Query: 69  GGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQG--RYSSSDWVTQYRMLYSDTGRNWKP 126
           G    W+PS +D   W+QV+   R  ++ + TQG  R +S +++  +++ YS  G  +  
Sbjct: 112 GMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDF 171

Query: 127 YHQ-DGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
            H  +     F GN N + V  +  + P+ A+YVR+ P   +      LR E+ GC
Sbjct: 172 IHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCH--TACTLRFELLGC 225



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 555 IDRCVPNHCEHGGKCSQ--------TWDSFKCTCDETGYSGATCHNSIYEP 597
           +D C  N C +GG C +         + S+ CTC + GY+G  C     EP
Sbjct: 24  LDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLK-GYAGNHCETKCVEP 73


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 59/146 (40%), Positives = 84/146 (57%), Gaps = 10/146 (6%)

Query: 1015 LRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEEIRFSFSTTKAPCILLYISSFTT 1072
            + Y+FQ   T + +SSS V +       H D  L +E I  SF TT+ P +LLY+SSF  
Sbjct: 1    MTYHFQEHYTLSENSSSLVSSL------HRDVTLTREMITLSFRTTRTPSLLLYVSSFYE 54

Query: 1073 DFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYP 1132
            ++L+V++   GSLQIRY L   + P     D +NMA+GQ H V I R E  + ++++   
Sbjct: 55   EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQ-- 112

Query: 1133 SVSYHLPSSSDTLFNSPKSLFLGKVI 1158
            S    +  SS T FN+ KSL LGKV+
Sbjct: 113  SAKKQVILSSGTEFNAVKSLILGKVL 138


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 52/143 (36%), Positives = 79/143 (55%), Gaps = 7/143 (4%)

Query: 47   AFSSSSSISGSY-SPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQG--R 103
            A S   S  G Y  P  A++N +G    W    +++ QWL++D    K+I+AI TQG   
Sbjct: 2084 ASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKS 2143

Query: 104  YSSSDWVTQYRMLYSDTGRNWKPYHQDGNI--WAFPGNINSDGVVRHELQHPIIARYVRI 161
             SS  +V  Y + YS+ G  WKPY    ++    F GN N+ G V++    PII+R++R+
Sbjct: 2144 LSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRV 2203

Query: 162  VPLDWNGEGRIGLRIEVYGCSYW 184
            +P  WN    I LR+E++GC  +
Sbjct: 2204 IPKTWNQS--IALRLELFGCDIY 2224



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 50/177 (28%), Positives = 79/177 (44%), Gaps = 19/177 (10%)

Query: 51   SSSISGSYSPGYAKINKRGGAGGWS----PSDSDHYQWLQVDFGNRKQISAIATQG--RY 104
            +S   G + P  A++N  G    WS     ++     W+QVD      I+ I TQG   Y
Sbjct: 1925 ASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHY 1984

Query: 105  SSSDWVTQYRMLYSDTGRNWKPYHQDG--NIWAFPGNINSDGVVRHELQHPIIARYVRIV 162
              S + T++ + YS    NW+ +  +   N+  F GN ++  +  ++   PI+ARY+RI 
Sbjct: 1985 LKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRIS 2044

Query: 163  PLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTS 219
            P       R  LR+E+ GC               P    N K++  K + A +FK S
Sbjct: 2045 PT--RAYNRPTLRLELQGCEV--------NGCSTPLGMENGKIEN-KQITASSFKKS 2090


>gi|33469931 EGF-like, fibronectin type III and laminin G domains
           isoform 2 [Homo sapiens]
          Length = 775

 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 106/433 (24%), Positives = 180/433 (41%), Gaps = 66/433 (15%)

Query: 212 IALNFKTSESEGVILH-GEGQ--QGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTG 268
           I L F+    +G++L+ GE +  +GD+++L + +  L    N G+  +  I   T +  G
Sbjct: 177 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTG-VAIIVSETKIKLG 235

Query: 269 SLLDDHHWHSVVIERQGRSINLTLDRSMQHF-RTNGEFDYLDLDYEITFGGIPFSG--KP 325
                  WH+V++ R G +  L L+       ++ G++  +     +  GG P +     
Sbjct: 236 G------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 289

Query: 326 SSSSRKNFKGCMESINYNG--VNITDLARRKKLEPSNVGNLSF------SCVEPYTVPVF 377
           ++ + + F+GC++S+  NG  +++      K L  ++VG  S       SC+   T    
Sbjct: 290 ATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAI 349

Query: 378 FNATSY-----LEVPGRLNQDLFSVSF-QFRT---------W--NPNGLLVFSHF----- 415
             A SY     L   GR  +D F+++  QFR          W   P   L F  F     
Sbjct: 350 -KADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFR 408

Query: 416 ---ADNLGNVEIDLTESKVGVHINITQTKMS-QIDISSGSG-------LNDGQWHEVRFL 464
               D +     D T SK  + IN+    +  + D  SG+G       L  G WHE+R  
Sbjct: 409 PDSGDGVLLYSYD-TGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVS 467

Query: 465 AKENFAILTIDGDE-ASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQL 523
                 IL +D  +    +      Q+K     F GG  N  +   +S +   F G +Q 
Sbjct: 468 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 527

Query: 524 IQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDET 583
           I ++D+ +++      K    + V+++  A    CV   C HGG C    + + C C   
Sbjct: 528 IILNDRTIHV------KHDFTSGVNVENAA--HPCVRAPCAHGGSCRPRKEGYDCDC-PL 578

Query: 584 GYSGATCHNSIYE 596
           G+ G  C  +I E
Sbjct: 579 GFEGLHCQKAIIE 591



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 99/396 (25%), Positives = 163/396 (41%), Gaps = 63/396 (15%)

Query: 806  PSSYLHFSTFQGETSADISFYFKTLTPWGVFLENM--GKEDFIKLELKSATEVSFSFDVG 863
            P  YL F  F+          F+  +  GV L +   G +DF+ + L     V F FD G
Sbjct: 394  PQHYLSFMEFE--------ITFRPDSGDGVLLYSYDTGSKDFLSINLAGG-HVEFRFDCG 444

Query: 864  NGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEG-HTRLELYSQL 922
            +G    V+RS  PL    WH +   R  K   LQVD+  Q+I +   EG  T+++  + +
Sbjct: 445  SGTG--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDI 500

Query: 923  FVGG----------AGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGF-ISGCSGHCTSYG 971
            F+GG          +G  + F G I+ + +N  T+ ++     TSG  +   +  C    
Sbjct: 501  FIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAHPCVR-- 556

Query: 972  TNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWL---RYNFQAPATNARD 1028
              C +GG C  R  GY CDC    ++G  C K +    E   ++      +  P    R 
Sbjct: 557  APCAHGGSCRPRKEGYDCDCP-LGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRV 615

Query: 1029 SSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSF----TTDFLAVLVKPTGS 1084
            S SR                  +   F TT    +LL+         +DF+++ ++  G+
Sbjct: 616  SGSR----------------SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLR-DGA 658

Query: 1085 LQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDT 1144
            L   YNLG       +   + +  +G+ H V   R  ++  + +D Y + +   P     
Sbjct: 659  LVFSYNLGSGVASIMV---NGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQ 715

Query: 1145 LFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLS 1180
            L N   +L++G + E   I    ++    G  GC+S
Sbjct: 716  L-NINGALYVGGMKE---IALHTNRQYMRGLVGCIS 747



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 81/344 (23%), Positives = 136/344 (39%), Gaps = 48/344 (13%)

Query: 808  SYLHFSTFQGETSA-DISFYFKTLTPWGVFL----ENMGKEDFIKLELKSATEVSFSFDV 862
            SY+ F   +    A  I+  F+     G+ L       G+ DF+ L +   + + F F+ 
Sbjct: 161  SYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRS-LQFRFNC 219

Query: 863  GNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQL 922
            G G   IV  S T +    WH V   R+     LQ++       ++  + ++++   + L
Sbjct: 220  GTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQ-YSKITFRTPL 276

Query: 923  FVGGA----------GGQQGFLGCIRSLRMNGVTLDLE--ERAKVTSGFISG--CSGHCT 968
            ++GGA          G  +GF GC++SL +NG  +D+      K  SG   G   SG C 
Sbjct: 277  YLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICD 336

Query: 969  SYGTNCENGGKCLE-RYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNAR 1027
                +C +GG C   +   Y C C    + G  C                 F       R
Sbjct: 337  E--ASCIHGGTCTAIKADSYICLCP-LGFKGRHCED--------------AFTLTIPQFR 379

Query: 1028 DSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLY-ISSFTTDFLAVLVKPTGSLQ 1086
            +S       P        L+  E   +F       +LLY   + + DFL++ +   G ++
Sbjct: 380  ESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVE 438

Query: 1087 IRYNLG-GTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLD 1129
             R++ G GT    + D     +  G  H + ++R  K   L++D
Sbjct: 439  FRFDCGSGTGVLRSED----PLTLGNWHELRVSRTAKNGILQVD 478



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 11/95 (11%)

Query: 203 KKMKTLKDVIALNFKTSESEGVIL-HGEGQQ---GDYITLELKKAKLVLSLNLGSNQLGP 258
           K++   +  + + FKT+  +G++L  G+       D+I+L L+   LV S NLGS     
Sbjct: 613 KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGS----- 667

Query: 259 IYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLD 293
             G  S+M     +D  WH V   R G+S  +T+D
Sbjct: 668 --GVASIMVNGSFNDGRWHRVKAVRDGQSGKITVD 700



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 62/307 (20%), Positives = 116/307 (37%), Gaps = 56/307 (18%)

Query: 214 LNFKTSESEGVILHG-EGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLD 272
           + F+    +GV+L+  +    D++++ L    +    + GS   G +     +  G+   
Sbjct: 405 ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGT-GVLRSEDPLTLGN--- 460

Query: 273 DHHWHSVVIERQGRSINLTLDRS-MQHFRTNGEFDYLDLDYEITFGGIPFSG--KPSSSS 329
              WH + + R  ++  L +D+  +      G F  +  + +I  GG+P     K +S  
Sbjct: 461 ---WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGV 517

Query: 330 RKNFKGCMESINYN------------GVNITDLARRKKLEPSNVGNL------SFSC--- 368
            K F G ++ I  N            GVN+ + A      P   G         + C   
Sbjct: 518 LKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCP 577

Query: 369 ------------VEPYTVPVFFNATSYL-----EVPGRLNQDLFSVSFQFRTWNPNGLLV 411
                       +E   +P F    SYL     ++  R++    +V  +F+T   +GLL+
Sbjct: 578 LGFEGLHCQKAIIEAIEIPQFIGR-SYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLL 636

Query: 412 F---SHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKEN 468
           +   S    N   + + L +  +    N+     S   I      NDG+WH V+ +    
Sbjct: 637 WRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVAS---IMVNGSFNDGRWHRVKAVRDGQ 693

Query: 469 FAILTID 475
              +T+D
Sbjct: 694 SGKITVD 700



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 52/241 (21%), Positives = 92/241 (38%), Gaps = 29/241 (12%)

Query: 367 SCVEPYTV--PVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVF----SHFADNLG 420
           SC E   +  P FF  +     P + +   F ++ +FR    +GLL++     H   +  
Sbjct: 145 SCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFM 204

Query: 421 NVEIDLTESK------VGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTI 474
           ++ I     +       GV I +++TK+             G WH V         +L +
Sbjct: 205 SLAIIRRSLQFRFNCGTGVAIIVSETKIKL-----------GGWHTVMLYRDGLNGLLQL 253

Query: 475 -DGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNL 533
            +G   +        ++      + GG  +       +     FQGC+Q + V+ + +++
Sbjct: 254 NNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDM 313

Query: 534 YEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQ-TWDSFKCTCDETGYSGATCHN 592
                 K  S A+V      I D      C HGG C+    DS+ C C   G+ G  C +
Sbjct: 314 RPWPLGKALSGADVGECSSGICDEA---SCIHGGTCTAIKADSYICLC-PLGFKGRHCED 369

Query: 593 S 593
           +
Sbjct: 370 A 370


>gi|33469929 EGF-like, fibronectin type III and laminin G domains
           isoform 1 [Homo sapiens]
          Length = 1009

 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 106/433 (24%), Positives = 180/433 (41%), Gaps = 66/433 (15%)

Query: 212 IALNFKTSESEGVILH-GEGQ--QGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTG 268
           I L F+    +G++L+ GE +  +GD+++L + +  L    N G+  +  I   T +  G
Sbjct: 411 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTG-VAIIVSETKIKLG 469

Query: 269 SLLDDHHWHSVVIERQGRSINLTLDRSMQHF-RTNGEFDYLDLDYEITFGGIPFSG--KP 325
                  WH+V++ R G +  L L+       ++ G++  +     +  GG P +     
Sbjct: 470 G------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 523

Query: 326 SSSSRKNFKGCMESINYNG--VNITDLARRKKLEPSNVGNLSF------SCVEPYTVPVF 377
           ++ + + F+GC++S+  NG  +++      K L  ++VG  S       SC+   T    
Sbjct: 524 ATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAI 583

Query: 378 FNATSY-----LEVPGRLNQDLFSVSF-QFRT---------W--NPNGLLVFSHF----- 415
             A SY     L   GR  +D F+++  QFR          W   P   L F  F     
Sbjct: 584 -KADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFR 642

Query: 416 ---ADNLGNVEIDLTESKVGVHINITQTKMS-QIDISSGSG-------LNDGQWHEVRFL 464
               D +     D T SK  + IN+    +  + D  SG+G       L  G WHE+R  
Sbjct: 643 PDSGDGVLLYSYD-TGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVS 701

Query: 465 AKENFAILTIDGDE-ASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQL 523
                 IL +D  +    +      Q+K     F GG  N  +   +S +   F G +Q 
Sbjct: 702 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 761

Query: 524 IQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDET 583
           I ++D+ +++      K    + V+++  A    CV   C HGG C    + + C C   
Sbjct: 762 IILNDRTIHV------KHDFTSGVNVENAA--HPCVRAPCAHGGSCRPRKEGYDCDC-PL 812

Query: 584 GYSGATCHNSIYE 596
           G+ G  C  +I E
Sbjct: 813 GFEGLHCQKAIIE 825



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 99/396 (25%), Positives = 163/396 (41%), Gaps = 63/396 (15%)

Query: 806  PSSYLHFSTFQGETSADISFYFKTLTPWGVFLENM--GKEDFIKLELKSATEVSFSFDVG 863
            P  YL F  F+          F+  +  GV L +   G +DF+ + L     V F FD G
Sbjct: 628  PQHYLSFMEFE--------ITFRPDSGDGVLLYSYDTGSKDFLSINLAGG-HVEFRFDCG 678

Query: 864  NGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEG-HTRLELYSQL 922
            +G    V+RS  PL    WH +   R  K   LQVD+  Q+I +   EG  T+++  + +
Sbjct: 679  SGTG--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDI 734

Query: 923  FVGG----------AGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGF-ISGCSGHCTSYG 971
            F+GG          +G  + F G I+ + +N  T+ ++     TSG  +   +  C    
Sbjct: 735  FIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAHPCVR-- 790

Query: 972  TNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWL---RYNFQAPATNARD 1028
              C +GG C  R  GY CDC    ++G  C K +    E   ++      +  P    R 
Sbjct: 791  APCAHGGSCRPRKEGYDCDCP-LGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRV 849

Query: 1029 SSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSF----TTDFLAVLVKPTGS 1084
            S SR                  +   F TT    +LL+         +DF+++ ++  G+
Sbjct: 850  SGSR----------------SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLR-DGA 892

Query: 1085 LQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDT 1144
            L   YNLG       +   + +  +G+ H V   R  ++  + +D Y + +   P     
Sbjct: 893  LVFSYNLGSGVASIMV---NGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQ 949

Query: 1145 LFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLS 1180
            L N   +L++G + E   I    ++    G  GC+S
Sbjct: 950  L-NINGALYVGGMKE---IALHTNRQYMRGLVGCIS 981



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 81/344 (23%), Positives = 136/344 (39%), Gaps = 48/344 (13%)

Query: 808  SYLHFSTFQGETSA-DISFYFKTLTPWGVFL----ENMGKEDFIKLELKSATEVSFSFDV 862
            SY+ F   +    A  I+  F+     G+ L       G+ DF+ L +   + + F F+ 
Sbjct: 395  SYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRS-LQFRFNC 453

Query: 863  GNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQL 922
            G G   IV  S T +    WH V   R+     LQ++       ++  + ++++   + L
Sbjct: 454  GTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQ-YSKITFRTPL 510

Query: 923  FVGGA----------GGQQGFLGCIRSLRMNGVTLDLE--ERAKVTSGFISG--CSGHCT 968
            ++GGA          G  +GF GC++SL +NG  +D+      K  SG   G   SG C 
Sbjct: 511  YLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICD 570

Query: 969  SYGTNCENGGKCLE-RYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNAR 1027
                +C +GG C   +   Y C C    + G  C                 F       R
Sbjct: 571  E--ASCIHGGTCTAIKADSYICLCP-LGFKGRHCED--------------AFTLTIPQFR 613

Query: 1028 DSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLY-ISSFTTDFLAVLVKPTGSLQ 1086
            +S       P        L+  E   +F       +LLY   + + DFL++ +   G ++
Sbjct: 614  ESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVE 672

Query: 1087 IRYNLG-GTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLD 1129
             R++ G GT    + D     +  G  H + ++R  K   L++D
Sbjct: 673  FRFDCGSGTGVLRSED----PLTLGNWHELRVSRTAKNGILQVD 712



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 11/95 (11%)

Query: 203 KKMKTLKDVIALNFKTSESEGVIL-HGEGQQ---GDYITLELKKAKLVLSLNLGSNQLGP 258
           K++   +  + + FKT+  +G++L  G+       D+I+L L+   LV S NLGS     
Sbjct: 847 KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGS----- 901

Query: 259 IYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLD 293
             G  S+M     +D  WH V   R G+S  +T+D
Sbjct: 902 --GVASIMVNGSFNDGRWHRVKAVRDGQSGKITVD 934



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 62/307 (20%), Positives = 116/307 (37%), Gaps = 56/307 (18%)

Query: 214 LNFKTSESEGVILHG-EGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLD 272
           + F+    +GV+L+  +    D++++ L    +    + GS   G +     +  G+   
Sbjct: 639 ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGT-GVLRSEDPLTLGN--- 694

Query: 273 DHHWHSVVIERQGRSINLTLDRS-MQHFRTNGEFDYLDLDYEITFGGIPFSG--KPSSSS 329
              WH + + R  ++  L +D+  +      G F  +  + +I  GG+P     K +S  
Sbjct: 695 ---WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGV 751

Query: 330 RKNFKGCMESINYN------------GVNITDLARRKKLEPSNVGNL------SFSC--- 368
            K F G ++ I  N            GVN+ + A      P   G         + C   
Sbjct: 752 LKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCP 811

Query: 369 ------------VEPYTVPVFFNATSYL-----EVPGRLNQDLFSVSFQFRTWNPNGLLV 411
                       +E   +P F    SYL     ++  R++    +V  +F+T   +GLL+
Sbjct: 812 LGFEGLHCQKAIIEAIEIPQFIGR-SYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLL 870

Query: 412 F---SHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKEN 468
           +   S    N   + + L +  +    N+     S   I      NDG+WH V+ +    
Sbjct: 871 WRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVAS---IMVNGSFNDGRWHRVKAVRDGQ 927

Query: 469 FAILTID 475
              +T+D
Sbjct: 928 SGKITVD 934



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 52/241 (21%), Positives = 92/241 (38%), Gaps = 29/241 (12%)

Query: 367 SCVEPYTV--PVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVF----SHFADNLG 420
           SC E   +  P FF  +     P + +   F ++ +FR    +GLL++     H   +  
Sbjct: 379 SCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFM 438

Query: 421 NVEIDLTESK------VGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTI 474
           ++ I     +       GV I +++TK+             G WH V         +L +
Sbjct: 439 SLAIIRRSLQFRFNCGTGVAIIVSETKIKL-----------GGWHTVMLYRDGLNGLLQL 487

Query: 475 -DGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNL 533
            +G   +        ++      + GG  +       +     FQGC+Q + V+ + +++
Sbjct: 488 NNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDM 547

Query: 534 YEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQ-TWDSFKCTCDETGYSGATCHN 592
                 K  S A+V      I D      C HGG C+    DS+ C C   G+ G  C +
Sbjct: 548 RPWPLGKALSGADVGECSSGICDEA---SCIHGGTCTAIKADSYICLC-PLGFKGRHCED 603

Query: 593 S 593
           +
Sbjct: 604 A 604


>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
           sapiens]
          Length = 224

 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 25/189 (13%)

Query: 16  WIVSSCLCRA-------WTAPSTSQKCDEPLVSGLP-----------HVAFSSSSSISGS 57
           W   +C C         W+A +TS  C        P            +  S+     G 
Sbjct: 33  WYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGW 92

Query: 58  YSP---GYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYR 114
           YS      A++N +G    W     D  QWLQ+D    K IS I TQGR    +W+T+Y 
Sbjct: 93  YSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDEWMTKYS 152

Query: 115 MLY-SDTGRNWKPY-HQDGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRI 172
           + Y +D   NW  Y  Q GN   F GN +    V++ L+ PII+R++R++PL W+   RI
Sbjct: 153 VQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWH--VRI 210

Query: 173 GLRIEVYGC 181
            +R+E+  C
Sbjct: 211 AIRMELLEC 219


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 99/369 (26%), Positives = 158/369 (42%), Gaps = 35/369 (9%)

Query: 212  IALNFKTSESEGVILHGE--GQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGS 269
            I  +F+T   EG+I+     G Q +Y  L+LKK +L     L   Q  P+   T+   G 
Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYF---LFDPQGSPVEVTTTNDHGK 1600

Query: 270  LLDDHHWHSVVIERQGRSINLTLDRSMQHFRT--NGEFDYLDLDYEITFGGIPFS----G 323
               D  WH ++  R      +TLD          NG     D +  +  GG+P S     
Sbjct: 1601 QYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGD-NTGVFLGGLPRSYTILR 1659

Query: 324  KPSSSSRKNFKGCMESI----NYNGVNITD-LARRKKLEPSNVGNLSFSCVEPYTVPVFF 378
            K     +K F GC++ +    NYN   I + L  +   E  NV N    C         F
Sbjct: 1660 KDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQF 1719

Query: 379  NATSYLEVP-----GRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGV 433
                +LE+      G +N   F +SF+FRT   NGLL+F +  D    + ++L    +  
Sbjct: 1720 LGAGFLELHPYMFHGGMN---FEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTF 1776

Query: 434  HINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRT-NSPLQVKT 492
             +N T    +Q+D+  G    +G+W++V    + +F   +++G    A  + + PL V +
Sbjct: 1777 RLN-TSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVVNS 1835

Query: 493  GEKYFFGGFLNQMNNS-SHSVLQPSFQGCMQLIQ-VDDQLVNLYEVAQRKPGSFANVSID 550
                + GG   ++ NS  H  L+  F GCM+ ++     +VNL  V+         V++D
Sbjct: 1836 --PVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTRGAVVNLASVS----SGAVRVNLD 1889

Query: 551  MCAIIDRCV 559
             C   D  V
Sbjct: 1890 GCLSTDSAV 1898



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 20/159 (12%)

Query: 378  FNATSYLEVPGR---LNQDLFSVSFQFRTWNPNGLLVFS--------HFADNLGNVEIDL 426
            F    Y + P     +N D   +   FRT  P GL+VF+        +FA  L    +  
Sbjct: 1522 FIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYF 1581

Query: 427  TESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDG-DEASAVRTN 485
                 G  + +T T         G   +DG+WHE+  +  + F  +T+DG    S+   N
Sbjct: 1582 LFDPQGSPVEVTTTN------DHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILN 1635

Query: 486  SPLQVKTGEKYFFGGFLNQMN--NSSHSVLQPSFQGCMQ 522
                +      F GG             ++Q  F GC++
Sbjct: 1636 GSTVIGDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLK 1674


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 47/151 (31%), Positives = 80/151 (52%), Gaps = 8/151 (5%)

Query: 37  EPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQIS 96
           +P ++    + ++  +    S+ P  A++ K G    W+   +D YQWLQ+D    K+I+
Sbjct: 305 DPQITASSVLEWTDHTGQENSWKPKKARLKKPGPP--WAAFATDEYQWLQIDLNKEKKIT 362

Query: 97  AIATQG--RYSSSDWVTQYRMLYSDTGRNWKPYHQDG--NIWAFPGNINSDGVVRHELQH 152
            I T G      + +V+ YR+LYSD G+ W  Y + G      F GN +    VR+    
Sbjct: 363 GIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLP 422

Query: 153 PIIARYVRIVPLDWNGEGRIGLRIEVYGCSY 183
           PIIAR++R+ P  W  + +I +++E+ GC +
Sbjct: 423 PIIARFIRVNPTQW--QQKIAMKMELLGCQF 451


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 70/239 (29%), Positives = 114/239 (47%), Gaps = 32/239 (13%)

Query: 50  SSSSISGSYSPGYAKINKRGGA-------GGWSPSDSDHYQWLQVDFGNRKQISAIATQG 102
           +SS +         ++N + GA       G W   D    QW++VD     + + + TQG
Sbjct: 402 ASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQG 461

Query: 103 RYSS--SDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPIIARYVR 160
           R SS   D+VT + + +S+  + W  Y        F GN++ D  V  EL  P++AR++R
Sbjct: 462 RDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIR 521

Query: 161 IVPLDWNGEGRIGLRIEVYGC------SYWA--DVINFDGHVVLPYRFRN-KKMKTLKDV 211
           I PL WNG   + +R+EV GC      SY+A  +V+  D    L +R  + K M+ L  V
Sbjct: 522 IYPLTWNGS--LCMRLEVLGCSVAPVYSYYAQNEVVATDD---LDFRHHSYKDMRQLMKV 576

Query: 212 IALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLG-PIYGHTSVMTGS 269
           +  N +          G+  +G      LK   + +S N G ++LG P + +T+ + G+
Sbjct: 577 V--NEECPTITRTYSLGKSSRG------LKIYAMEISDNPGEHELGEPEFRYTAGIHGN 627


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 51/157 (32%), Positives = 81/157 (51%), Gaps = 14/157 (8%)

Query: 35  CDEPLVSGLPHVAFSSSSSISGSY--------SPGYAKINKRGGAGGWSPSDSDHYQWLQ 86
           C  PL  G+   A S +   + SY        SP  A+++ +G +  W P  ++  +WLQ
Sbjct: 58  CSMPL--GMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQ 115

Query: 87  VDFGNRKQISAIATQGRYS--SSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDG 144
           VDF    +++ + TQG  S  +S +V ++ +  S  G  W  + Q+G +  F GN +S  
Sbjct: 116 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175

Query: 145 VVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
            V + L  P++ RY+RI P  W    +I LR+EV GC
Sbjct: 176 PVVNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210



 Score = 37.4 bits (85), Expect = 0.097
 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%)

Query: 136 FPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
           F GN++S G+  +    PIIARY+R+ P  ++   R  LR+E+ GC
Sbjct: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYS--IRSTLRMELMGC 53


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 51/157 (32%), Positives = 81/157 (51%), Gaps = 14/157 (8%)

Query: 35   CDEPLVSGLPHVAFSSSSSISGSY--------SPGYAKINKRGGAGGWSPSDSDHYQWLQ 86
            C  PL  G+   A S +   + SY        SP  A+++ +G +  W P  ++  +WLQ
Sbjct: 2193 CSMPL--GMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQ 2250

Query: 87   VDFGNRKQISAIATQGRYS--SSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDG 144
            VDF    +++ + TQG  S  +S +V ++ +  S  G  W  + Q+G +  F GN +S  
Sbjct: 2251 VDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 2310

Query: 145  VVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
             V + L  P++ RY+RI P  W    +I LR+EV GC
Sbjct: 2311 PVVNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 2345



 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 49/156 (31%), Positives = 81/156 (51%), Gaps = 10/156 (6%)

Query: 32   SQKCDEPLVSGLPHVAFS--SSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDF 89
            S KC  PL     H+     ++S   G ++P  A+++  G    WS  +   + W++VD 
Sbjct: 2037 SNKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEP--FSWIKVDL 2094

Query: 90   GNRKQISAIATQGRYS--SSDWVTQYRMLYSDTGRNWKPY--HQDGNIWAFPGNINSDGV 145
                 I  I TQG     SS +++Q+ ++YS  G+ W+ Y  +  G +  F GN++S G+
Sbjct: 2095 LAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGI 2154

Query: 146  VRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
              +    PIIARY+R+ P  ++   R  LR+E+ GC
Sbjct: 2155 KHNIFNPPIIARYIRLHPTHYS--IRSTLRMELMGC 2188


>gi|4504229 glycophorin C isoform 1 [Homo sapiens]
          Length = 128

 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 49/122 (40%), Positives = 64/122 (52%), Gaps = 4/122 (3%)

Query: 1213 NCGASPLTLSP---MSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIA 1269
            N  A PL+L P   M+SA+   H   +          P            +  +I GVIA
Sbjct: 8    NSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIVVIAGVIA 67

Query: 1270 VVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEW 1329
             V   ++  L  ++RYM+RHKGTYHTNEAKG E AESADAA +  DP   +  D S+KE+
Sbjct: 68   AVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAA-LQGDPALQDAGDSSRKEY 126

Query: 1330 LI 1331
             I
Sbjct: 127  FI 128


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 2/112 (1%)

Query: 72  GGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSS--SDWVTQYRMLYSDTGRNWKPYHQ 129
           G W    +D  QW++VD     + + + TQGR S   SDWVT Y+++ S+    W     
Sbjct: 182 GAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN 241

Query: 130 DGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
                 F GN   +  V +EL  P++ARY+RI P  W   G I +R+E+ GC
Sbjct: 242 GSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293


>gi|31317224 EGF-like repeats and discoidin I-like
           domains-containing protein 3 [Homo sapiens]
          Length = 480

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 15/161 (9%)

Query: 35  CDEPLVSGLPHVA---------FSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWL 85
           C EPL     H+          F + +    ++ P  A+++K+G    W+   +D  QWL
Sbjct: 319 CSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWL 378

Query: 86  QVDFGNRKQISAIATQGR--YSSSDWVTQYRMLYSDTGRNWKPYHQD--GNIWAFPGNIN 141
           QVD     +++ I TQG   +    +V  Y++ YS+ G +W  Y  +       F GN +
Sbjct: 379 QVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFD 438

Query: 142 SDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGCS 182
           +D   ++ +  PI AR++RI+P  W+  GRI LR E+ GC+
Sbjct: 439 NDTHRKNVIDPPIYARHIRILP--WSWYGRITLRSELLGCT 477



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 49/175 (28%), Positives = 87/175 (49%), Gaps = 15/175 (8%)

Query: 20  SCLCRA-WTAPSTSQKCDEPL------VSGLPHVAFSSSSSISG--SYSPGYAKINKRGG 70
           SC C   +   +   KC  PL      +S     A S+  ++ G   + P YA++NK+G 
Sbjct: 142 SCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGL 201

Query: 71  AGGWSPSDSDHYQWLQVDFGNRKQISAIATQG--RYSSSDWVTQYRMLYSDTGRNWKPYH 128
              W+ +++D + W+Q++   + +++ + TQG  R  S +++  Y++ YS+ G+ W  Y 
Sbjct: 202 INAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYK 261

Query: 129 QDG--NIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
             G      F GNI+++    +    PI A+YVR+ P          LR+E+ GC
Sbjct: 262 VKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVC--RRHCTLRMELLGC 314



 Score = 34.3 bits (77), Expect = 0.82
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 8/56 (14%)

Query: 558 CVPNHCEHGGKC-------SQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLG 606
           C PN C +GG C         T+  + C C   G++G  C ++I E   E  K+ G
Sbjct: 78  CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPR-GFNGIHCQHNINECEVEPCKNGG 132



 Score = 31.2 bits (69), Expect = 6.9
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 16/71 (22%)

Query: 556 DRCVPNHCEHGGKC--SQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYW 613
           D C PN CE+GG C       SF C C + G++   C + +   S E             
Sbjct: 24  DICDPNPCENGGICLPGLADGSFSCECPD-GFTDPNCSSVVEVASDEE------------ 70

Query: 614 IDPDGSGPLGP 624
            +P  +GP  P
Sbjct: 71  -EPTSAGPCTP 80


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,679,850
Number of Sequences: 37866
Number of extensions: 2542638
Number of successful extensions: 7123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 107
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 5481
Number of HSP's gapped (non-prelim): 1224
length of query: 1331
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1217
effective length of database: 13,930,794
effective search space: 16953776298
effective search space used: 16953776298
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.