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Search of human proteins with 7019357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019357 crystallin, beta A2 [Homo sapiens]
(197 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16936542 crystallin, beta A2 [Homo sapiens] 421 e-118
gi|16936540 crystallin, beta A2 [Homo sapiens] 421 e-118
gi|7019357 crystallin, beta A2 [Homo sapiens] 421 e-118
gi|12056461 crystallin, beta A3 [Homo sapiens] 235 2e-62
gi|4503059 crystallin, beta A4 [Homo sapiens] 221 3e-58
gi|4503061 crystallin, beta B1 [Homo sapiens] 166 9e-42
gi|4758074 crystallin, beta B3 [Homo sapiens] 144 5e-35
gi|4503063 crystallin, beta B2 [Homo sapiens] 134 4e-32
gi|21389517 gammaN-crystallin [Homo sapiens] 109 2e-24
gi|8922120 crystallin, gamma S [Homo sapiens] 103 7e-23
gi|148491057 crystallin, gamma A [Homo sapiens] 103 9e-23
gi|10518338 crystallin, gamma C [Homo sapiens] 99 3e-21
gi|148491074 crystallin, gamma B [Homo sapiens] 94 7e-20
gi|62988361 absent in melanoma 1 [Homo sapiens] 90 1e-18
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi... 89 2e-18
gi|13377002 crystallin, gamma D [Homo sapiens] 89 3e-18
gi|89886227 absent in melanoma 1-like [Homo sapiens] 88 5e-18
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 30 1.3
gi|134244285 Notch homolog 3 [Homo sapiens] 29 2.3
gi|134031945 SCO-spondin [Homo sapiens] 28 5.0
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 27 8.6
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 27 8.6
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 27 8.6
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 27 8.6
gi|45120115 hypothetical protein LOC56905 [Homo sapiens] 27 8.6
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 27 8.6
>gi|16936542 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 421 bits (1082), Expect = e-118
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
Query: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 181 GTQAHTGQLQSIRRVQH 197
GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197
>gi|16936540 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 421 bits (1082), Expect = e-118
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
Query: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 181 GTQAHTGQLQSIRRVQH 197
GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197
>gi|7019357 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 421 bits (1082), Expect = e-118
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
Query: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK
Sbjct: 61 PDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCK 120
Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL
Sbjct: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
Query: 181 GTQAHTGQLQSIRRVQH 197
GTQAHTGQLQSIRRVQH
Sbjct: 181 GTQAHTGQLQSIRRVQH 197
>gi|12056461 crystallin, beta A3 [Homo sapiens]
Length = 215
Score = 235 bits (600), Expect = 2e-62
Identities = 104/193 (53%), Positives = 145/193 (75%), Gaps = 2/193 (1%)
Query: 5 PAPGP-APASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDF 63
P PG P +T++D+E+FQG+R S C NV ER VRS+KVE+G W+ +E+ F
Sbjct: 23 PTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERS-FDNVRSLKVESGAWIGYEHTSF 81
Query: 64 QGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDL 123
GQQFILE+G+YPRW AWSGS++++ +L+SFRP+ ANH +S++T+FE +NF G ++++
Sbjct: 82 CGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEI 141
Query: 124 VDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQ 183
DDYPSL +MGW + +VGS+K+ SGAWV YQYPGYRGYQY+LE D H G++ + E G+
Sbjct: 142 SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSH 201
Query: 184 AHTGQLQSIRRVQ 196
A T Q+QSIRR+Q
Sbjct: 202 AQTSQIQSIRRIQ 214
>gi|4503059 crystallin, beta A4 [Homo sapiens]
Length = 196
Score = 221 bits (563), Expect = 3e-58
Identities = 102/186 (54%), Positives = 134/186 (72%), Gaps = 1/186 (0%)
Query: 11 PASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70
P + +WDE+ FQGRR ++C +V E G VRS+KV +G WV FE+ FQGQQ+IL
Sbjct: 11 PWKMVVWDEDGFQGRRHEFTAECPSVLELG-FETVRSLKVLSGAWVGFEHAGFQGQQYIL 69
Query: 71 EKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSL 130
E+G+YP W AW G++++ + +L SFRP CANH DSR+T+FE +NF G K +L DDYPSL
Sbjct: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSL 129
Query: 131 PSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQ 190
+MGW +VGS V SGAWV Q+PGYRG+QYVLE D HSG++ + E G+ A T Q+Q
Sbjct: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189
Query: 191 SIRRVQ 196
SIRR+Q
Sbjct: 190 SIRRIQ 195
>gi|4503061 crystallin, beta B1 [Homo sapiens]
Length = 252
Score = 166 bits (421), Expect = 9e-42
Identities = 91/189 (48%), Positives = 129/189 (68%), Gaps = 12/189 (6%)
Query: 9 PAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQF 68
P L +++ E+FQGRR +C+N+ +RG RVRS+ V G WVAFE +F+G+ F
Sbjct: 56 PGNYRLVVFELENFQGRRAEFSGECSNLADRG-FDRVRSIIVSAGPWVAFEQSNFRGEMF 114
Query: 69 ILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDY 127
ILEKG+YPRW+ W SSS+ S++L+SFRP+ + + +++LFEG NF+G ++ DD
Sbjct: 115 ILEKGEYPRWNTW--SSSYRSDRLMSFRPIK-MDAQEHKISLFEGANFKGNTIEIQGDDA 171
Query: 128 PSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTG 187
PSL G++ + VGS+KVSSG WV YQYPGYRGYQY+LE G+F + E G A
Sbjct: 172 PSLWVYGFSDR-VGSVKVSSGTWVGYQYPGYRGYQYLLE----PGDFRHWNEWG--AFQP 224
Query: 188 QLQSIRRVQ 196
Q+QS+RR++
Sbjct: 225 QMQSLRRLR 233
>gi|4758074 crystallin, beta B3 [Homo sapiens]
Length = 211
Score = 144 bits (363), Expect = 5e-35
Identities = 82/182 (45%), Positives = 120/182 (65%), Gaps = 12/182 (6%)
Query: 16 LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75
L++ E+FQG+RC L ++C ++ + L +V S++VE+G W+AFE F+G+QF+LEKGDY
Sbjct: 28 LYELENFQGKRCELSAECPSLTD-SLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDY 86
Query: 76 PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLV-DDYPSLPSMG 134
PRW AW S+S +S+ LLS RP L + ++ LFE F G K ++V DD PSL + G
Sbjct: 87 PRWDAW--SNSRDSDSLLSLRP-LNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
Query: 135 WASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIRR 194
+ + V S++ +G WV Y++PGYRG QYV ER GE+ + E A QLQS+RR
Sbjct: 144 FQDR-VASVRAINGTWVGYEFPGYRGRQYVFER----GEYRHWNE--WDASQPQLQSVRR 196
Query: 195 VQ 196
++
Sbjct: 197 IR 198
Score = 49.7 bits (117), Expect = 2e-06
Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
+V L+E +NFQG + +L + PSL + VGS++V SG W+A++ +RG Q+VLE
Sbjct: 25 KVILYELENFQGKRCELSAECPSLTDS--LLEKVGSIQVESGPWLAFESRAFRGEQFVLE 82
Query: 167 RDRHSGEFCTYGELGTQAHTGQLQSIR 193
+ G++ + + L S+R
Sbjct: 83 K----GDYPRWDAWSNSRDSDSLLSLR 105
>gi|4503063 crystallin, beta B2 [Homo sapiens]
Length = 205
Score = 134 bits (338), Expect = 4e-32
Identities = 74/196 (37%), Positives = 117/196 (59%), Gaps = 12/196 (6%)
Query: 2 SSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYP 61
+ A P + ++++E+FQG L C N+ E G + + SV V+ G WV +E
Sbjct: 7 TQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPWVGYEQA 65
Query: 62 DFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKF 121
+ +G+QF+ EKG+YPRW +W +SS ++ L S RP+ + + ++ L+E NF G K
Sbjct: 66 NCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKM 122
Query: 122 DLV-DDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL 180
+++ DD PS + G+ K V S++V SG WV YQYPGYRG QY+LE+ G++ +
Sbjct: 123 EIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDYKDSSDF 177
Query: 181 GTQAHTGQLQSIRRVQ 196
G A Q+QS+RR++
Sbjct: 178 G--APHPQVQSVRRIR 191
>gi|21389517 gammaN-crystallin [Homo sapiens]
Length = 182
Score = 109 bits (272), Expect = 2e-24
Identities = 58/140 (41%), Positives = 82/140 (58%), Gaps = 9/140 (6%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+TL++ + F G++ + DC N +RG + RV S+ VE+G WV F +PDF+GQQFILE G
Sbjct: 8 ITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEHG 67
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132
DYP + W+ S H + S RPV H + R+ +FEG NF G + ++D P L S
Sbjct: 68 DYPDFFRWNSHSDH----MGSCRPV--GMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121
Query: 133 MGWASKDVGSLKV--SSGAW 150
GW V ++KV AW
Sbjct: 122 RGWVKNCVNTIKVYGDGAAW 141
Score = 53.5 bits (127), Expect = 1e-07
Identities = 23/60 (38%), Positives = 39/60 (65%), Gaps = 1/60 (1%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
++TL+EG +F G K ++ D + G+ ++ V S+ V SGAWV + +P +RG Q++LE
Sbjct: 7 KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNR-VNSIHVESGAWVCFNHPDFRGQQFILE 65
>gi|8922120 crystallin, gamma S [Homo sapiens]
Length = 178
Score = 103 bits (258), Expect = 7e-23
Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 7/157 (4%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+T +++++FQGRR DCA+ L R S+KVE G W +E P+F G +IL +G
Sbjct: 8 ITFYEDKNFQGRRYDCDCDCADF--HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
+YP + W G +++L S R V + ++ +FE +F G ++ +D PS+
Sbjct: 66 EYPEYQRWMGL----NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
+ +++ S KV G W+ Y+ P YRG QY+L++ +
Sbjct: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157
Score = 56.6 bits (135), Expect = 1e-08
Identities = 22/79 (27%), Positives = 45/79 (56%)
Query: 7 PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
P + ++++ DF G+ DC ++ E+ + + S KV GVW+ +E P+++G+
Sbjct: 89 PSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148
Query: 67 QFILEKGDYPRWSAWSGSS 85
Q++L+K +Y + W +S
Sbjct: 149 QYLLDKKEYRKPIDWGAAS 167
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
+++T +E NFQG ++D D + + S+ S+KV G W Y+ P + GY Y+L
Sbjct: 6 TKITFYEDKNFQGRRYDCDCDCADFHT--YLSR-CNSIKVEGGTWAVYERPNFAGYMYIL 62
Query: 166 ERDRHSGEFCTY 177
+ GE+ Y
Sbjct: 63 PQ----GEYPEY 70
>gi|148491057 crystallin, gamma A [Homo sapiens]
Length = 174
Score = 103 bits (257), Expect = 9e-23
Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 14/180 (7%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+T +++ DFQGR +SDC N+ R R S++V++G W+ +E P++QG Q+ L +G
Sbjct: 4 ITFYEDRDFQGRCYNCISDCPNL--RVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
YP + W G S+ + S R + + + ++ L+E D+++G +L DD +P +
Sbjct: 62 KYPDYQHWMGL----SDSVQSCR--IIPHTSSHKLRLYERDDYRGLMSELTDDCACVPEL 115
Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGEL-GTQAHTGQLQSI 192
+ ++ SL V G WV Y+ P YRG QY+L G++ Y + G A G L+ +
Sbjct: 116 -FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWGGADAKVGSLRRV 170
Score = 66.2 bits (160), Expect = 2e-11
Identities = 29/80 (36%), Positives = 47/80 (58%)
Query: 7 PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
P + L L++ +D++G L DCA V E LP + S+ V G WV +E P+++G+
Sbjct: 83 PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPEIYSLHVLEGCWVLYEMPNYRGR 142
Query: 67 QFILEKGDYPRWSAWSGSSS 86
Q++L GDY R+ W G+ +
Sbjct: 143 QYLLRPGDYRRYHDWGGADA 162
Score = 47.4 bits (111), Expect = 8e-06
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
++T +E +FQG ++ + D P+L S++V SG W+ Y+ P Y+G+QY L
Sbjct: 3 KITFYEDRDFQGRCYNCISDCPNLRVY---FSRCNSIRVDSGCWMLYERPNYQGHQYFLR 59
Query: 167 RDRH 170
R ++
Sbjct: 60 RGKY 63
>gi|10518338 crystallin, gamma C [Homo sapiens]
Length = 174
Score = 98.6 bits (244), Expect = 3e-21
Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 9/152 (5%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+T +++ FQGR +DC N+ + R S++VE+G W+ +E P++QGQQ++L +G
Sbjct: 4 ITFYEDRAFQGRSYETTTDCPNL--QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
+YP + W G S + L + V R+ L+E ++ +G +L +D PS+
Sbjct: 62 EYPDYQQWMGLSDSIRSCCLIPQTV------SHRLRLYEREDHKGLMMELSEDCPSIQDR 115
Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
S ++ SL V G WV Y+ P YRG QY+L
Sbjct: 116 FHLS-EIRSLHVLEGCWVLYELPNYRGRQYLL 146
Score = 56.2 bits (134), Expect = 2e-08
Identities = 24/68 (35%), Positives = 40/68 (58%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
L L++ ED +G L DC ++ +R L +RS+ V G WV +E P+++G+Q++L
Sbjct: 90 LRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ 149
Query: 74 DYPRWSAW 81
+Y R W
Sbjct: 150 EYRRCQDW 157
Score = 46.2 bits (108), Expect = 2e-05
Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
++T +E FQG ++ D P+L S++V SG W+ Y+ P Y+G QY+L
Sbjct: 3 KITFYEDRAFQGRSYETTTDCPNLQPY---FSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
Query: 167 RDRHSGEFCTY 177
R GE+ Y
Sbjct: 60 R----GEYPDY 66
>gi|148491074 crystallin, gamma B [Homo sapiens]
Length = 175
Score = 94.0 bits (232), Expect = 7e-20
Identities = 55/182 (30%), Positives = 96/182 (52%), Gaps = 14/182 (7%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+T +++ FQGR +DC N+ + R S++VE+G W+ +E P++QG Q+ L +G
Sbjct: 4 ITFYEDRAFQGRSYECTTDCPNL--QPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRRG 61
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
+YP + W G S + L + + R+ +++ D +G +L DD S+
Sbjct: 62 EYPDYQQWMGLSDSIRSCCL-----IPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDR 116
Query: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQSIR 193
+ ++ SL V G+W+ Y+ P YRG QY+L GE+ + + G A ++ S+R
Sbjct: 117 -FHLTEIHSLNVLEGSWILYEMPNYRGRQYLL----RPGEYRRFLDWG--APNAKVGSLR 169
Query: 194 RV 195
RV
Sbjct: 170 RV 171
Score = 46.6 bits (109), Expect = 1e-05
Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
++T +E FQG ++ D P+L S++V SG W+ Y+ P Y+G+QY L
Sbjct: 3 KITFYEDRAFQGRSYECTTDCPNLQPY---FSRCNSIRVESGCWMIYERPNYQGHQYFLR 59
Query: 167 RDRHSGEFCTY 177
R GE+ Y
Sbjct: 60 R----GEYPDY 66
>gi|62988361 absent in melanoma 1 [Homo sapiens]
Length = 1723
Score = 90.1 bits (222), Expect = 1e-18
Identities = 54/173 (31%), Positives = 91/173 (52%), Gaps = 20/173 (11%)
Query: 9 PAPASLTLWDEEDFQGRRCRLLSDCANVCERGG----------LP--RVRSVKVENGVWV 56
P + ++++ F+G+ L + + GG LP V S+KV G+WV
Sbjct: 1215 PTDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWV 1274
Query: 57 AFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNF 116
A+E P F G Q++LE+G+Y W AW G + +L S RP+L + +++ + ++ NF
Sbjct: 1275 AYEKPGFTGHQYLLEEGEYRDWKAWGG----YNGELQSLRPIL-GDFSNAHMIMYSEKNF 1329
Query: 117 --QGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER 167
+G D++ +L G+ K S+ V SG WVAY+ P + G QY+L++
Sbjct: 1330 GSKGSSIDVLGIVANLKETGYGVK-TQSINVLSGVWVAYENPDFTGEQYILDK 1381
Score = 84.0 bits (206), Expect = 8e-17
Identities = 60/198 (30%), Positives = 94/198 (47%), Gaps = 26/198 (13%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+ L+ E + G D + G + + S+KV G W+ +E P FQG FILE G
Sbjct: 1125 IDLFTEPEGLGILSSYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPG 1184
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANH-----NDSRVTLFEGDNFQGCKFDLVDDYP 128
+YP S W +++ + S RP+ D +V ++E F+G +L
Sbjct: 1185 EYPDLSFWDTEAAY----IGSMRPLKMGGRKVEFPTDPKVVVYEKPFFEGKCVELETGMC 1240
Query: 129 SLPSMGWASKD-----------VGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTY 177
S G +++ VGS+KV G WVAY+ PG+ G+QY+LE GE+ +
Sbjct: 1241 SFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEKPGFTGHQYLLE----EGEYRDW 1296
Query: 178 GELGTQAHTGQLQSIRRV 195
G + G+LQS+R +
Sbjct: 1297 KAWG--GYNGELQSLRPI 1312
Score = 79.3 bits (194), Expect = 2e-15
Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
Query: 12 ASLTLWDEEDF--QGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFI 69
A + ++ E++F +G +L AN+ E G + +S+ V +GVWVA+E PDF G+Q+I
Sbjct: 1319 AHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYI 1378
Query: 70 LEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSR----VTLFEGDNFQGCKFDLVD 125
L+KG Y + W G + ++ S +P+ + R + LF FQG
Sbjct: 1379 LDKGFYTSFEDWGGKNC----KISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHS----Q 1430
Query: 126 DYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
+ S S S +VS G+WV Y + G QYVLE +
Sbjct: 1431 SFEETTSQIDDSFSTKSCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475
Score = 71.2 bits (173), Expect = 5e-13
Identities = 46/150 (30%), Positives = 78/150 (52%), Gaps = 8/150 (5%)
Query: 16 LWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDY 75
L+ E FQG + + + +S +V G WV ++ +F G Q++LE+G Y
Sbjct: 1419 LFSEPQFQGHSQSFEETTSQIDDSFS---TKSCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475
Query: 76 PRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGW 135
P SA G + + L F V ++ + LFE ++F+G K +L + +L S+G+
Sbjct: 1476 PCLSA-MGCPPGATFKSLRFIDV---EFSEPTIILFEREDFKGKKIELNAETVNLRSLGF 1531
Query: 136 ASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
+ + S++V G WV Y+Y YRG Q++L
Sbjct: 1532 -NTQIRSVQVIGGIWVTYEYGSYRGRQFLL 1560
Score = 65.1 bits (157), Expect = 4e-11
Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 10/166 (6%)
Query: 9 PAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQF 68
P P + ++ E D + + SD + C L V +KV G W+ +E P+F+G
Sbjct: 1019 PRPGKVVIYSEPDVSEKCIEVFSDIQD-CSSWSLSPVILIKVVRGCWILYEQPNFEGHSI 1077
Query: 69 ILEKGDYPRWSAWS-GSSSHNSNQLLSFRPVLCA-------NHNDSRVTLFEGDNFQGCK 120
LE+G+ W + S +PV+ ++ S + LF G
Sbjct: 1078 PLEEGELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGIL 1137
Query: 121 FDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
DD + G K S+KV G W+ Y+ PG++G ++LE
Sbjct: 1138 SSYFDDTEEMQGFGVMQKTC-SMKVHWGTWLIYEEPGFQGVPFILE 1182
Score = 63.2 bits (152), Expect = 1e-10
Identities = 29/85 (34%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Query: 13 SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
++ L++ EDF+G++ L ++ N+ G ++RSV+V G+WV +EY ++G+QF+L
Sbjct: 1503 TIILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSP 1562
Query: 73 GDYPRWSAWSGSSSHNSNQLLSFRP 97
+ P W +SG Q+ S RP
Sbjct: 1563 AEVPNWYEFSG-----CRQIGSLRP 1582
>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
sapiens]
Length = 1022
Score = 89.4 bits (220), Expect = 2e-18
Identities = 56/132 (42%), Positives = 78/132 (59%), Gaps = 7/132 (5%)
Query: 40 GGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVL 99
G R+ S++V GVWVA+E F+GQQF+LE+GD+ +A SS +LSFR L
Sbjct: 563 GDFHRIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSS----PILSFR-YL 617
Query: 100 CANHNDSRVTLFEGDNFQGCKFDLVD-DYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGY 158
AN +S VTLFE D G D+ + + L +G+ SK S+ V SG WVAYQ +
Sbjct: 618 QANFIESSVTLFESDLESGKFIDITNQEISDLEEIGFGSK-TRSIHVKSGVWVAYQQKFF 676
Query: 159 RGYQYVLERDRH 170
G QY+LE+ ++
Sbjct: 677 CGEQYILEKGKY 688
Score = 63.2 bits (152), Expect = 1e-10
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 14/147 (9%)
Query: 12 ASLTLWDEEDFQGRRCRLLS-DCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70
+S+TL++ + G+ + + + +++ E G + RS+ V++GVWVA++ F G+Q+IL
Sbjct: 624 SSVTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYIL 683
Query: 71 EKGDYPRWSAWSGSSSHNSNQLLSFRPV----LCANHNDSRVTLFEGDNFQGCKFDLVDD 126
EKG Y + W GS +N ++S RP+ L N + F FQG D ++
Sbjct: 684 EKGKYKCFFDWGGS----NNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEE 739
Query: 127 YPSLPSMGWASKDVGSLKVSSGAWVAY 153
L S+ S KV G W+ Y
Sbjct: 740 TSDLTSLMPC-----SFKVLRGCWLLY 761
Score = 49.3 bits (116), Expect = 2e-06
Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 16/128 (12%)
Query: 47 SVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHN-- 104
S V++GVW+A+ +F+GQ +LE+ G ++ ++ S P+
Sbjct: 475 SFTVKSGVWLAYPDINFKGQATVLEEDH--------GLFEISTAEMKSLHPLQMGGLKVE 526
Query: 105 ---DSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKD---VGSLKVSSGAWVAYQYPGY 158
+ +V ++E +F G + + S+P+ + D +GS++V G WVAY+ +
Sbjct: 527 MPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHF 586
Query: 159 RGYQYVLE 166
+G Q++LE
Sbjct: 587 KGQQFLLE 594
Score = 48.9 bits (115), Expect = 3e-06
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 4/131 (3%)
Query: 48 VKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAW--SGSSSHNSNQLLSFRPVLCANHND 105
+KV G W+ +E P F+GQ+ +LE+G+ W N +L + + +
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSI 440
Query: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
+ LF + C + P+L + SK V S V SG W+AY ++G VL
Sbjct: 441 PEIELFPQSDPACCPVYIQRAVPNLEELN-ISKSV-SFTVKSGVWLAYPDINFKGQATVL 498
Query: 166 ERDRHSGEFCT 176
E D E T
Sbjct: 499 EEDHGLFEIST 509
Score = 43.5 bits (101), Expect = 1e-04
Identities = 22/70 (31%), Positives = 40/70 (57%)
Query: 13 SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
S++L+ E +GR L +V + +SV V++G+W+A+E +F G+Q +L
Sbjct: 805 SISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRP 864
Query: 73 GDYPRWSAWS 82
+ P W+A+S
Sbjct: 865 NEIPNWTAFS 874
Score = 32.7 bits (73), Expect = 0.20
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 14/123 (11%)
Query: 47 SVKVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS 106
S KV G W+ + D +LE+G Y ++ +S ++ S +P+ S
Sbjct: 750 SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPAS----KVKSLKPIDYVFEEPS 805
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVG----SLKVSSGAWVAYQYPGYRGYQ 162
++LF ++ +G + L + S+ +KD+ S+ V SG W+AY+ + G Q
Sbjct: 806 -ISLFALEHCEGRELHLEEAVNSV-----LNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQ 859
Query: 163 YVL 165
+L
Sbjct: 860 ILL 862
Score = 30.8 bits (68), Expect = 0.78
Identities = 14/41 (34%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 127 YPSLP-SMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
Y ++P + W+ + +KV G W+ Y+ P +RG + VLE
Sbjct: 364 YCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFRGQKCVLE 404
>gi|13377002 crystallin, gamma D [Homo sapiens]
Length = 174
Score = 88.6 bits (218), Expect = 3e-18
Identities = 56/181 (30%), Positives = 91/181 (50%), Gaps = 16/181 (8%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
+TL+++ FQGR SD N+ + L R S +V++G W+ +E P++ G Q+ L +G
Sbjct: 4 ITLYEDRGFQGRHYECSSDHPNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132
DY W G S S R H+ S R+ L+E ++++G + +D L
Sbjct: 62 DYADHQQWMGLSD-------SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114
Query: 133 MGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELG-TQAHTGQLQS 191
+ ++ SL V G+WV Y+ YRG QY+L G++ Y + G T A G L+
Sbjct: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWGATNARVGSLRR 169
Query: 192 I 192
+
Sbjct: 170 V 170
Score = 46.6 bits (109), Expect = 1e-05
Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
Query: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166
++TL+E FQG ++ D+P+L + S+ S +V SG W+ Y+ P Y G QY L
Sbjct: 3 KITLYEDRGFQGRHYECSSDHPNL--QPYLSR-CNSARVDSGCWMLYEQPNYSGLQYFLR 59
Query: 167 R 167
R
Sbjct: 60 R 60
>gi|89886227 absent in melanoma 1-like [Homo sapiens]
Length = 616
Score = 87.8 bits (216), Expect = 5e-18
Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 11/164 (6%)
Query: 9 PAPASLTLWDEEDFQGRRCRLLSDCANV-----CERGGLPRVRSVKVENGVWVAFEYPDF 63
P +++ FQGR + D N+ + L V S++V G WV +E F
Sbjct: 120 PGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGF 179
Query: 64 QGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDL 123
+G Q++LE+G+YP WS W G ++LL+ V+ + D V LFE +F+G ++
Sbjct: 180 RGHQYLLEEGEYPDWSHWGG-----YDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEV 234
Query: 124 VDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER 167
P + + ++ V SG WVAYQ G+ G QYVLE+
Sbjct: 235 SKALPDV-ELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEK 277
Score = 81.3 bits (199), Expect = 5e-16
Identities = 57/186 (30%), Positives = 89/186 (47%), Gaps = 18/186 (9%)
Query: 13 SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
++ L++ DF+G + +V P +++ V +GVWVA++ F G+Q++LEK
Sbjct: 218 AVVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEK 277
Query: 73 GDYPRWSAWSGSSSHNSNQLLSFRPVLCANHND----SRVTLFEGDNFQGCKFDLVDDYP 128
G Y W +S L S +PVL +D S++ LF +F G F DD
Sbjct: 278 GVYRNCEDWGAGNS----TLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQA 333
Query: 129 SLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHT-- 186
+LP AS S +V G+W+ + + G Q++L GEF T +G A T
Sbjct: 334 ALP----ASFRPQSCRVHGGSWILFDETNFEGDQHILS----EGEFPTLTAMGCLASTVL 385
Query: 187 GQLQSI 192
G LQ +
Sbjct: 386 GSLQKV 391
Score = 75.1 bits (183), Expect = 4e-14
Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 9/164 (5%)
Query: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
++L+ EE +G + +L N +V S V G+W+ + P F+ +ILE G
Sbjct: 30 ISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPG 89
Query: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCAN---HNDSRVTLFEGDNFQGCKFDLVDDYPSL 130
+YP AW G+S + L R + C + + R ++E FQG +++ D +L
Sbjct: 90 EYPTSEAW-GTSDPSVGSLKPMR-LGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNL 147
Query: 131 P----SMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
S VGSL+V G WV Y+ G+RG+QY+LE +
Sbjct: 148 QQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEY 191
Score = 54.7 bits (130), Expect = 5e-08
Identities = 39/157 (24%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 12 ASLTLWDEEDFQGRRCRLLSDCANVCERGGLP---RVRSVKVENGVWVAFEYPDFQGQQF 68
+ + L+ DF G D A LP R +S +V G W+ F+ +F+G Q
Sbjct: 311 SKIQLFSRPDFLGDHFSFEDDQA------ALPASFRPQSCRVHGGSWILFDETNFEGDQH 364
Query: 69 ILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYP 128
IL +G++P +A +S +L + + ++ + L+ + F+G + +L +
Sbjct: 365 ILSEGEFPTLTAMGCLAS----TVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVR 420
Query: 129 SLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
SL + G+ + V S+++ G WV ++ +RG Q+++
Sbjct: 421 SLQAEGF-NNHVLSVRIKGGIWVLCEHSDFRGRQWLV 456
Score = 46.6 bits (109), Expect = 1e-05
Identities = 21/72 (29%), Positives = 41/72 (56%)
Query: 13 SLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEK 72
S+ L+ E F+G+ L + ++ G V SV+++ G+WV E+ DF+G+Q+++
Sbjct: 399 SIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGS 458
Query: 73 GDYPRWSAWSGS 84
+ W +SG+
Sbjct: 459 CEITNWLTYSGT 470
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 30.0 bits (66), Expect = 1.3
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 54 VWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEG 113
VWV Y + G Q+ + G+ R AW+ S+S S+ +SF+PV A + V + E
Sbjct: 499 VWV---YINILGGQYSDQAGN--RIRAWNWSNSITSSPFVSFKPVFLALNRYIGVRILEQ 553
Query: 114 D 114
D
Sbjct: 554 D 554
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 29.3 bits (64), Expect = 2.3
Identities = 13/20 (65%), Positives = 14/20 (70%), Gaps = 1/20 (5%)
Query: 23 QGRRCRLLSDCA-NVCERGG 41
QGR+C LLS C N CE GG
Sbjct: 765 QGRQCELLSPCTPNPCEHGG 784
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 28.1 bits (61), Expect = 5.0
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 5/36 (13%)
Query: 97 PVLCANHNDSRVTLFEGDNF-----QGCKFDLVDDY 127
P CA D F+G ++ QGC++ LV DY
Sbjct: 561 PAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDY 596
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 27.3 bits (59), Expect = 8.6
Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 35/183 (19%)
Query: 18 DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPR 77
DEE +Q RR S+ ++ G +P R +VE W + D
Sbjct: 510 DEEWWQARRVHSDSETDDI---GFIPSKR--RVERREWSRLKAKD--------------- 549
Query: 78 WSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWAS 137
W + SGS + +LS+ V + +R + G DL+ ++P
Sbjct: 550 WGSSSGSQGREDS-VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPD-------- 600
Query: 138 KDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQAHTGQLQSI 192
K + ++ Y+ G R Y +V +E+D + +F G+ + + +QS+
Sbjct: 601 KFGSCVPHTTRPKREYEIDG-RDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 659
Query: 193 RRV 195
R V
Sbjct: 660 REV 662
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 27.3 bits (59), Expect = 8.6
Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 35/183 (19%)
Query: 18 DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKGDYPR 77
DEE +Q RR S+ ++ G +P R +VE W + D
Sbjct: 464 DEEWWQARRVHSDSETDDI---GFIPSKR--RVERREWSRLKAKD--------------- 503
Query: 78 WSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSMGWAS 137
W + SGS + +LS+ V + +R + G DL+ ++P
Sbjct: 504 WGSSSGSQGREDS-VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPD-------- 554
Query: 138 KDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQAHTGQLQSI 192
K + ++ Y+ G R Y +V +E+D + +F G+ + + +QS+
Sbjct: 555 KFGSCVPHTTRPKREYEIDG-RDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 613
Query: 193 RRV 195
R V
Sbjct: 614 REV 616
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 27.3 bits (59), Expect = 8.6
Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 33/192 (17%)
Query: 18 DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILE-KGDYP 76
D+E +Q RR L D E G +P R +VE + F + +++ KGD P
Sbjct: 472 DDEWWQARRVMLEGDSE---EMGVIPSKR--RVERKERARLKTVKFNAKPGVIDSKGDIP 526
Query: 77 RWSAWSGSSSHNSNQ---LLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPS---- 129
+ Q +LS+ PV N +R + G DL+ ++P
Sbjct: 527 GLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGS 586
Query: 130 -LPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQ 183
+P +D Y+ G R Y +V +E+D +F G+
Sbjct: 587 CVPHTTRPKRD-------------YEVDG-RDYHFVISREQMEKDIQEHKFIEAGQYNDN 632
Query: 184 AHTGQLQSIRRV 195
+ +QS+R V
Sbjct: 633 LYGTSVQSVRFV 644
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 27.3 bits (59), Expect = 8.6
Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 33/192 (17%)
Query: 18 DEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILE-KGDYP 76
D+E +Q RR L D E G +P R +VE + F + +++ KGD P
Sbjct: 57 DDEWWQARRVMLEGDSE---EMGVIPSKR--RVERKERARLKTVKFNAKPGVIDSKGDIP 111
Query: 77 RWSAWSGSSSHNSNQ---LLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPS---- 129
+ Q +LS+ PV N +R + G DL+ ++P
Sbjct: 112 GLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGS 171
Query: 130 -LPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYV-----LERDRHSGEFCTYGELGTQ 183
+P +D Y+ G R Y +V +E+D +F G+
Sbjct: 172 CVPHTTRPKRD-------------YEVDG-RDYHFVISREQMEKDIQEHKFIEAGQYNDN 217
Query: 184 AHTGQLQSIRRV 195
+ +QS+R V
Sbjct: 218 LYGTSVQSVRFV 229
>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
Length = 1047
Score = 27.3 bits (59), Expect = 8.6
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 4 APAPGPAPASLTLWD---EEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEY 60
AP GPAPAS + E+ F G L + ++R G W +
Sbjct: 746 APVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPPEKLREWLETAGPWGQAAW 805
Query: 61 PDFQGQQFILEK 72
D QG Q +L K
Sbjct: 806 QDCQGVQGLLAK 817
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 27.3 bits (59), Expect = 8.6
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 79 SAWSGSSSHNS-NQLLSFRPVLCANHNDSRVTLFEGDN 115
S +S SS+H S N LL VL +NH + ++ F G N
Sbjct: 272 SHYSFSSNHISPNSLLQSSAVLASNHTNQTLSDFTGSN 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,930,432
Number of Sequences: 37866
Number of extensions: 411010
Number of successful extensions: 1216
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1098
Number of HSP's gapped (non-prelim): 58
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.