Guide to the Human Genome
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Search of human proteins with 52630344

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52630344 major histocompatibility complex, class II, DR beta
4 precursor [Homo sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52630344 major histocompatibility complex, class II, DR beta ...   548   e-156
gi|239758090 PREDICTED: major histocompatibility complex, class ...   482   e-136
gi|155030211 major histocompatibility complex, class II, DR beta...   479   e-136
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...   479   e-135
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...   477   e-135
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...   473   e-134
gi|239740695 PREDICTED: similar to HLA class II histocompatibili...   473   e-134
gi|239740857 PREDICTED: similar to major histocompatibility comp...   473   e-134
gi|239740853 PREDICTED: similar to major histocompatibility comp...   472   e-133
gi|18641375 major histocompatibility complex, class II, DR beta ...   467   e-132
gi|17986005 major histocompatibility complex, class II, DR beta ...   460   e-130
gi|239740859 PREDICTED: similar to major histocompatibility comp...   456   e-129
gi|239740855 PREDICTED: similar to major histocompatibility comp...   456   e-129
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...   410   e-115
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...   410   e-115
gi|239740693 PREDICTED: similar to HLA class II histocompatibili...   410   e-115
gi|169168591 PREDICTED: similar to major histocompatibility comp...   337   6e-93
gi|239740920 PREDICTED: similar to major histocompatibility comp...   333   9e-92
gi|239740918 PREDICTED: similar to major histocompatibility comp...   333   9e-92
gi|150418002 major histocompatibility complex, class II, DQ beta...   333   1e-91
gi|239758095 PREDICTED: similar to major histocompatibility comp...   331   5e-91
gi|239740749 PREDICTED: similar to major histocompatibility comp...   331   5e-91
gi|239748788 PREDICTED: similar to major histocompatibility comp...   328   2e-90
gi|239740863 PREDICTED: similar to major histocompatibility comp...   328   3e-90
gi|239513955 PREDICTED: similar to major histocompatibility comp...   328   3e-90
gi|169217452 PREDICTED: similar to HLA class II histocompatibili...   324   6e-89
gi|24797076 major histocompatibility complex, class II, DP beta ...   308   3e-84
gi|4504403 major histocompatibility complex, class II, DO beta p...   292   2e-79
gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa...   261   4e-70
gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa...   257   6e-69

>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score =  548 bits (1412), Expect = e-156
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI
Sbjct: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV
Sbjct: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLGTGLFIYFRNQKGHSGLQPTGLLS
Sbjct: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score =  482 bits (1241), Expect = e-136
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 35  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 94
           RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK
Sbjct: 47  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 106

Query: 95  DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 154
           DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG
Sbjct: 107 DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 166

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT
Sbjct: 167 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 226

Query: 215 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 266
           VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS
Sbjct: 227 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 278


>gi|155030211 major histocompatibility complex, class II, DR beta 1
           precursor [Homo sapiens]
          Length = 266

 Score =  479 bits (1234), Expect = e-136
 Identities = 233/266 (87%), Positives = 247/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCM ALTVTL VLSSPLAL+GDT+PRFL Q K ECHF NGTERV  L RY 
Sbjct: 1   MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE  R++SD+GE++AVTELGRPDAEYWNSQKD+LE+ RA VDTYCR+NYGVVESFTV
Sbjct: 61  YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVQPKVTVYPSKTQPLQHHNLLVCSV+GFYPGSIEVRWF NGQEEKAG+VSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score =  479 bits (1233), Expect = e-135
 Identities = 236/266 (88%), Positives = 247/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL+Q K ECHF NGTERV  L R I
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGI 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE  R++SD+GEY+AVTELGRP AE WNSQKD LERRRAEVDT CR+NYGV ESFTV
Sbjct: 61  YNQEENVRFDSDVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score =  477 bits (1227), Expect = e-135
 Identities = 231/266 (86%), Positives = 245/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCL+LPGGSCMA LTVTL VLSSPLALAGDT+PRFLE+ K ECHF NGTERV  L RY 
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           +NQEE  R++SD+GE++AVTELGRPDAEYWNSQKDLLE+RRA VDTYCR+NYGV ESFTV
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV PKVTVYPSKTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEK GVVSTGLI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQP G LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  473 bits (1218), Expect = e-134
 Identities = 231/266 (86%), Positives = 245/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV  L R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE+ R++SD+GEY+AVTELGRP AE WNSQKD+LE RR +VDT CR+NYGV ESFTV
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  473 bits (1218), Expect = e-134
 Identities = 231/266 (86%), Positives = 245/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV  L R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE+ R++SD+GEY+AVTELGRP AE WNSQKD+LE RR +VDT CR+NYGV ESFTV
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  473 bits (1217), Expect = e-134
 Identities = 228/266 (85%), Positives = 243/266 (91%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCL+LPGGSCMA LTVTL VLSSPLALAGDT+PRFLE +  ECHF NGTERV  L RY 
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           +NQEE  R++SD+GE++AVTELGRPDAEYWNSQKDLLE++R  VD YCR+NYGVVESFTV
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV PKVTVYPSKTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEK GVVSTGLI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQP G LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  472 bits (1214), Expect = e-133
 Identities = 229/266 (86%), Positives = 246/266 (92%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGS +AALTVTL VLSS LA AGDT+PRFLE  K ECHF NGTERV  L R+ 
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           +NQEEYAR++SD+GEY+AV ELGRPDAEYWNSQKDLLE++R +VD YCR+NYGV ESFTV
Sbjct: 61  HNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+WSARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score =  467 bits (1201), Expect = e-132
 Identities = 229/266 (86%), Positives = 244/266 (91%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGS MA LTVTL VLSSPLALAGDT+PRFL+Q K ECHF NGTERV  L R I
Sbjct: 1   MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE  R++SD+GEY+AVTELGRPDAEYWNSQKD LE RRA VDTYCR+NYGV ESFTV
Sbjct: 61  YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV+PKVTVYP++TQ LQHHNLLVCSVNGFYPGSIEVRWFRN QEEKAGVVSTGLIQNG
Sbjct: 121 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+W A+SESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYF+NQKGHSGL PTGL+S
Sbjct: 241 FLGAGLFIYFKNQKGHSGLHPTGLVS 266


>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score =  460 bits (1184), Expect = e-130
 Identities = 225/266 (84%), Positives = 241/266 (90%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGS +AALTVTL VLSS LA AGDT+PRFLE  K ECHF NGTERV  L RY 
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           +NQEE+ R++SD+GEY+AVTELGRP AE WNSQKDLLE++R  VD YCR+NYGV ESFTV
Sbjct: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+ S LTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  456 bits (1174), Expect = e-129
 Identities = 224/267 (83%), Positives = 239/267 (89%), Gaps = 1/267 (0%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRF-LEQAKCECHFLNGTERVWNLIRY 59
           MVCL+LPGGSCMA LTVTL VLSSPLALAGDT+ +  L     ECHF NGTERV  L RY
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRY 60

Query: 60  IYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFT 119
            +NQEE  R++SD+GE++AVTELGRPDAEYWNSQKDLLE++R  VD YCR+NYGVVESFT
Sbjct: 61  FHNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFT 120

Query: 120 VQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 179
           VQRRV PKVTVYPSKTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEK GVVSTGLI N
Sbjct: 121 VQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHN 180

Query: 180 GDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGL 239
           GDWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+W ARSESAQSKMLSGVGGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGL 240

Query: 240 LFLGTGLFIYFRNQKGHSGLQPTGLLS 266
           LFLG GLFIYFRNQKGHSGLQP G LS
Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPRGFLS 267


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  456 bits (1174), Expect = e-129
 Identities = 225/267 (84%), Positives = 243/267 (91%), Gaps = 1/267 (0%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRF-LEQAKCECHFLNGTERVWNLIRY 59
           MVCLKLPGGS +AALTVTL VLSS LA AGDT+ +  L   K ECHF NGTERV  L R+
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERH 60

Query: 60  IYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFT 119
            +NQEEYAR++SD+GEY+AV ELGRPDAEYWNSQKDLLE++R +VD YCR+NYGV ESFT
Sbjct: 61  FHNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFT 120

Query: 120 VQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 179
           VQRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQN
Sbjct: 121 VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 180

Query: 180 GDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGL 239
           GDWTFQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+WSARSESAQSKMLSGVGGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGL 240

Query: 240 LFLGTGLFIYFRNQKGHSGLQPTGLLS 266
           LFLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPTGFLS 267


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score =  410 bits (1054), Expect = e-115
 Identities = 210/266 (78%), Positives = 224/266 (84%), Gaps = 13/266 (4%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV  L R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEE+ R++SD+GEY+AVTELGRP AE    Q DLL          C  +   +  F +
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
              V P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227

Query: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  410 bits (1053), Expect = e-115
 Identities = 198/232 (85%), Positives = 212/232 (91%)

Query: 35  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 94
           RFL Q K +CHF NGTERV  L R  YNQEE+ R++SD+GEY+AVTELGRP AE WNSQK
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 154
           D+LE RR +VDT CR+NYGV ESFTVQRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPG
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 152

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLT
Sbjct: 153 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 212

Query: 215 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 266
           V+W ARSESAQSKMLSGVGGFVLGLLFLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 213 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  410 bits (1053), Expect = e-115
 Identities = 198/232 (85%), Positives = 212/232 (91%)

Query: 35  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 94
           RFL Q K +CHF NGTERV  L R  YNQEE+ R++SD+GEY+AVTELGRP AE WNSQK
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 154
           D+LE RR +VDT CR+NYGV ESFTVQRRV P+VTVYP+KTQPLQHHNLLVCSV+GFYPG
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 152

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 214
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLT
Sbjct: 153 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 212

Query: 215 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 266
           V+W ARSESAQSKMLSGVGGFVLGLLFLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 213 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score =  337 bits (864), Expect = 6e-93
 Identities = 162/252 (64%), Positives = 200/252 (79%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F+ Q K  C+F NGTERV  + RYIYN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EEYAR++SD+G Y+AVT LG P AEYWNSQK++LER RA VDT CR+NY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score =  333 bits (854), Expect = 9e-92
 Identities = 159/252 (63%), Positives = 199/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F+ Q K  C+F NGTERV  + RYIYN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EEYAR++SD+G Y+AVT LG P AEYWNSQK++LER RAE+DT CR+NY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ +P+ V+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score =  333 bits (854), Expect = 9e-92
 Identities = 159/252 (63%), Positives = 199/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F+ Q K  C+F NGTERV  + RYIYN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EEYAR++SD+G Y+AVT LG P AEYWNSQK++LER RAE+DT CR+NY +    T+QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ +P+ V+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|150418002 major histocompatibility complex, class II, DQ beta 1
           precursor [Homo sapiens]
          Length = 261

 Score =  333 bits (853), Expect = 1e-91
 Identities = 164/252 (65%), Positives = 198/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PG   +A +T+ L +LSS LA   D+   F+ Q K  C+F NGTERV  + RYIYN+
Sbjct: 7   LRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EEYAR++SD+G Y+AVT  GRPDAEYWNSQK++LE  RAE+DT CR+NY V     +QRR
Sbjct: 67  EEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYPG I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSGVGGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I  R+QKG
Sbjct: 247 LGLIIRQRSQKG 258


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  331 bits (848), Expect = 5e-91
 Identities = 160/252 (63%), Positives = 199/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG   A +T+ L++LS+P+A   D+   F+ Q K  C+F NGTERV  + R IYN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EE  R++SD+GE++AVT LG P AEYWNSQKD+LER+RA VD  CR+NY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  331 bits (848), Expect = 5e-91
 Identities = 160/252 (63%), Positives = 199/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG   A +T+ L++LS+P+A   D+   F+ Q K  C+F NGTERV  + R IYN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EE  R++SD+GE++AVT LG P AEYWNSQKD+LER+RA VD  CR+NY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239748788 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 2 [Homo sapiens]
          Length = 281

 Score =  328 bits (842), Expect = 2e-90
 Identities = 159/252 (63%), Positives = 198/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F+ Q K  C+F NGTERV  + R IYN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EE  R++SD+GE++AVT LG P AEYWNSQKD+LER+RA VD  CR+NY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740863 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  328 bits (841), Expect = 3e-90
 Identities = 159/252 (63%), Positives = 198/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG   A +T+ L++LS+P+A   D+   F+ Q K  C+F NGTERV  + R IYN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EE  R++SD+GE++AVT LG P AEYWNSQKD+LER+RA VD  CR+NY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239513955 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  328 bits (841), Expect = 3e-90
 Identities = 159/252 (63%), Positives = 198/252 (78%)

Query: 4   LKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQ 63
           L++PGG   A +T+ L++LS+P+A   D+   F+ Q K  C+F NGTERV  + R IYN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRR 123
           EE  R++SD+GE++AVT LG P AEYWNSQKD+LER+RA VD  CR+NY +    T+QRR
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           V+P VT+ PS+T+ L HHNLLVCSV  FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TV+W A+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 244 TGLFIYFRNQKG 255
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-4 beta chain, partial [Homo sapiens]
          Length = 223

 Score =  324 bits (830), Expect = 6e-89
 Identities = 153/177 (86%), Positives = 164/177 (92%)

Query: 35  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 94
           RFLEQ K ECHF NGTERV  L RY Y+QEEY R++SD+GEY+AVTELGRPDAEYWNSQK
Sbjct: 47  RFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQK 106

Query: 95  DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 154
           DLLE++RA VDTYCR+NYGV ESFTVQRRV P+VTVYP+KTQPLQHHNLLVCSVNGFYPG
Sbjct: 107 DLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPG 166

Query: 155 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMS 211
           SIEVRWFRNGQEEK GVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+ S
Sbjct: 167 SIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score =  308 bits (789), Expect = 3e-84
 Identities = 152/258 (58%), Positives = 191/258 (74%), Gaps = 2/258 (0%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           M+ L++       ALT  L VL + +     T   +L Q + EC+  NGT+R   L RYI
Sbjct: 1   MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYI 58

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YN+EE+AR++SD+GE++AVTELGRP AEYWNSQKD+LE +RA  D  CR+NY +    T+
Sbjct: 59  YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118

Query: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
           QRRVQP+V V PSK  PLQHHNLLVC V  FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178

Query: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
           DWTFQ LVMLE  P+ G+VYTCQVEH S+ SP+TV+W A+S+SA+SK L+G GGFVLGL+
Sbjct: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238

Query: 241 FLGTGLFIYFRNQKGHSG 258
             G G+F++ R++K   G
Sbjct: 239 ICGVGIFMHRRSKKVQRG 256


>gi|4504403 major histocompatibility complex, class II, DO beta
           precursor [Homo sapiens]
          Length = 273

 Score =  292 bits (748), Expect = 2e-79
 Identities = 140/252 (55%), Positives = 185/252 (73%)

Query: 12  MAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNS 71
           + AL V LT L S +    D+   F+ QAK +C+F NGTE+V  ++R+I+N EEY R++S
Sbjct: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68

Query: 72  DLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVY 131
           D+G + A+T+LG+PDAE WNS+ DLLER R  VD  CR+NY +   FTV R+VQP+VTVY
Sbjct: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128

Query: 132 PSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 191
           P +T  L  HNLL CSV GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188

Query: 192 TVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFR 251
             P  G VYTC V+H S++SP++V+W A+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248

Query: 252 NQKGHSGLQPTG 263
            QKG+   Q +G
Sbjct: 249 AQKGYVRTQMSG 260


>gi|169168671 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 241

 Score =  261 bits (667), Expect = 4e-70
 Identities = 124/140 (88%), Positives = 133/140 (95%)

Query: 124 VQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 183
           +QPK T+YP+KT+PL H N LVCSV+GFYPGSIEVRWF+NGQEEKA VVS GLIQNGDWT
Sbjct: 99  LQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDWT 158

Query: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLG 243
           FQTLVMLETVPRSGEVYTCQVEHPS+ SPLTV+WSAR+ESAQSKMLSGVGGFVLGLLFLG
Sbjct: 159 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFLG 218

Query: 244 TGLFIYFRNQKGHSGLQPTG 263
           TGLFIYFRNQKGHSGLQPTG
Sbjct: 219 TGLFIYFRNQKGHSGLQPTG 238


>gi|169168589 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 140

 Score =  257 bits (657), Expect = 6e-69
 Identities = 123/123 (100%), Positives = 123/123 (100%)

Query: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
           MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI
Sbjct: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
           YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV
Sbjct: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120

Query: 121 QRR 123
           QRR
Sbjct: 121 QRR 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,591,494
Number of Sequences: 37866
Number of extensions: 448250
Number of successful extensions: 1171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 1029
Number of HSP's gapped (non-prelim): 134
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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