Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 5174517

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174517 SMAD family member 7 [Homo sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174517 SMAD family member 7 [Homo sapiens]                        902   0.0  
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             374   e-104
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            247   2e-65
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   132   6e-31
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   127   3e-29
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   124   2e-28
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    124   2e-28
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              119   4e-27
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   115   8e-26
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            100   3e-21
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...    97   4e-20
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]              92   7e-19
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]               92   7e-19
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]         92   1e-18
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]         92   1e-18
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]         92   1e-18
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...    89   1e-17
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]    88   2e-17
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    50   3e-06
gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a ...    44   4e-04
gi|4503119 cancer/testis antigen 1B [Homo sapiens]                     42   0.001
gi|21281685 cancer/testis antigen 1A [Homo sapiens]                    42   0.001
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...    42   0.001
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         42   0.001
gi|109452587 family with sequence similarity 98, member B isofor...    42   0.001
gi|23510368 homeobox D11 [Homo sapiens]                                41   0.002
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    41   0.002
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               41   0.002
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               41   0.002
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               41   0.002

>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score =  902 bits (2332), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 60
           MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
Sbjct: 1   MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 60

Query: 61  CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 120
           CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
Sbjct: 61  CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 120

Query: 121 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 180
           TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
Sbjct: 121 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 180

Query: 181 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY 240
           ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
Sbjct: 181 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY 240

Query: 241 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 300
           LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
Sbjct: 241 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 300

Query: 301 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 360
           LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
Sbjct: 301 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 360

Query: 361 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 420
           FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
Sbjct: 361 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 420

Query: 421 VIFNSR 426
           VIFNSR
Sbjct: 421 VIFNSR 426


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score =  374 bits (960), Expect = e-104
 Identities = 229/509 (44%), Positives = 282/509 (55%), Gaps = 99/509 (19%)

Query: 1   MFRTKRSALVRRLWRSRA-PGGEDEEEGAGGGG------------------GGG----EL 37
           MFR+KRS LVRRLWRSR  P  E+   G GGGG                  GGG    E+
Sbjct: 1   MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV 60

Query: 38  R-----------------------------------GEGATDSRAHGAGGGGPG------ 56
           R                                   G GA  S    A  GGPG      
Sbjct: 61  RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120

Query: 57  --RAGCCLGKAVRGAKGHHHPHPPAAGAGA--AGGA------------EADLKALTHSVL 100
                CCL      A        P AGA    AGG             E +LK +T+S+L
Sbjct: 121 CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL 180

Query: 101 KKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLC 160
           K+LKER L+ LL+AVESRGG    C+L+P R D RLG       QPA P       LLL 
Sbjct: 181 KRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLRLG------GQPAPPQ------LLLG 227

Query: 161 KVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCNPHHLSRLCELESPPPPYSRY-PMDF 218
           ++FRWPDL+H+ E+K LC C S+    +   VCCNP+H SRLC  ESPPPPYSR  P D 
Sbjct: 228 RLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDE 287

Query: 219 LKPTADCPDAVPSSAETGGTNYL--APGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRL 276
            KP  D  D+  S  ET  TN L  APG  SD+ +  +    SHWC VAYWE +TRVGRL
Sbjct: 288 YKPL-DLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRL 346

Query: 277 YCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRS 336
           Y V + ++ IFYDLPQG+GFCLGQLN + +S+ V++ RSKIG GI L++E DGVW YNR 
Sbjct: 347 YAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRG 406

Query: 337 SYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQ 396
            +PIF+ S TLD P  R L+V KV PG+SIK FD+E++  LQ   + +    P+   +V+
Sbjct: 407 EHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERS-GLQHAPEPDAADGPYDPNSVR 465

Query: 397 ISFVKGWGQCYTRQFISSCPCWLEVIFNS 425
           ISF KGWG CY+RQFI+SCPCWLE++ N+
Sbjct: 466 ISFAKGWGPCYSRQFITSCPCWLEILLNN 494


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score =  247 bits (630), Expect = 2e-65
 Identities = 122/224 (54%), Positives = 156/224 (69%), Gaps = 5/224 (2%)

Query: 205 ESPPPPYSRY-PMDFLKPTADCPDAVPSSAETGGTNYL--APGGLSDSQLLLEPGDRSHW 261
           +SPPPPYSR  P D  KP  D  D+  S  ET  TN L  APG  SD+ +  +    SHW
Sbjct: 12  KSPPPPYSRLSPRDEYKPL-DLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHW 70

Query: 262 CVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGI 321
           C VAYWE +TRVGRLY V + ++ IFYDLPQG+GFCLGQLN + +S+ V++ RSKIG GI
Sbjct: 71  CSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGI 130

Query: 322 QLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPN 381
            L++E DGVW YNR  +PIF+ S TLD P  R L+V KV PG+SIK FD+E++  LQ   
Sbjct: 131 LLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERS-GLQHAP 189

Query: 382 DHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS 425
           + +    P+   +V+ISF KGWG CY+RQFI+SCPCWLE++ N+
Sbjct: 190 EPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNN 233


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  132 bits (332), Expect = 6e-31
 Identities = 117/404 (28%), Positives = 182/404 (45%), Gaps = 70/404 (17%)

Query: 79  AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
           A G+G AGG E +       +    S++KKLK+  +L+ L +A+ ++    T C+ +P  
Sbjct: 22  AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPRS 80

Query: 132 LDCRLGPGAPAGAQPAQPPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPEL 190
           LD RL           Q      LP ++ C+++RWPDL    E+K +  CE    +  + 
Sbjct: 81  LDGRL-----------QVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDE 129

Query: 191 VCCNPHHLSRLCELESPP-------------PPYSRY----------------------- 214
           VC NP+H  R+     PP             PP   Y                       
Sbjct: 130 VCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPE 189

Query: 215 --PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQLLLEP---GDRSHWCVVAY 266
             P  ++    +  D  +  S +TG    L+P  LS  +  L L+P    + + WC +AY
Sbjct: 190 TPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAY 249

Query: 267 WEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLT 324
           +E   RVG  +   +PSL  D F D      FCLG L++ N++  V+  R  IG G++L 
Sbjct: 250 YELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLY 309

Query: 325 REVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPN 381
                V+    S   IF++S   +         V K+ PG ++K F+ ++  +L  Q  N
Sbjct: 310 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVN 369

Query: 382 D-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424
              E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+  N
Sbjct: 370 QGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 413


>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  127 bits (318), Expect = 3e-29
 Identities = 107/377 (28%), Positives = 178/377 (47%), Gaps = 62/377 (16%)

Query: 98  SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
           S++KKLK+  QL+ L +A+ ++    T C+ +P  LD RL           Q      LP
Sbjct: 37  SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLP 84

Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYS 212
            ++ C+++RWPDL    E++ +  CE    +  + VC NP+H  R+     PP   P ++
Sbjct: 85  HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144

Query: 213 RYPMDF-------------------LKPTADCPDAVPSS--AETG-------------GT 238
             P +F                   ++P ++ P+  P    +E G             G+
Sbjct: 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204

Query: 239 NYLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLP 291
             L+P  +S +   L L+P    + + WC ++Y+E   RVG  +   +PS+ +  F D  
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264

Query: 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351
               FCLG L++ N++  V+  R  IG G++L      V+    S   IF++S   +   
Sbjct: 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324

Query: 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407
                 V K+ PG ++K F+ ++  +L  Q  N   E + Q     T+++SFVKGWG  Y
Sbjct: 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384

Query: 408 TRQFISSCPCWLEVIFN 424
            RQ ++S PCW+E+  N
Sbjct: 385 RRQTVTSTPCWIELHLN 401


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  124 bits (310), Expect = 2e-28
 Identities = 116/423 (27%), Positives = 181/423 (42%), Gaps = 78/423 (18%)

Query: 79  AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
           A G+G AGG E +       +    S++KKLK+  +L+ L +A+ ++    T C+ +P  
Sbjct: 22  AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPST 80

Query: 132 LDCRLGPGAPAGAQPAQPPSSYS-------------------LP-LLLCKVFRWPDLRHS 171
                G   P           YS                   LP ++ C+++RWPDL   
Sbjct: 81  CSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSH 140

Query: 172 SEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP-------------PPYSRY---- 214
            E+K +  CE    +  + VC NP+H  R+     PP             PP   Y    
Sbjct: 141 HELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSI 200

Query: 215 ---------------------PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQ 250
                                P  ++    +  D  +  S +TG    L+P  LS  +  
Sbjct: 201 PENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHS 260

Query: 251 LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDN 305
           L L+P    + + WC +AY+E   RVG  +   +PSL  D F D      FCLG L++ N
Sbjct: 261 LDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVN 320

Query: 306 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGF 364
           ++  V+  R  IG G++L      V+    S   IF++S   +         V K+ PG 
Sbjct: 321 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 380

Query: 365 SIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
           ++K F+ ++  +L  Q  N   E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 381 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 440

Query: 422 IFN 424
             N
Sbjct: 441 HLN 443


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  124 bits (310), Expect = 2e-28
 Identities = 116/423 (27%), Positives = 181/423 (42%), Gaps = 78/423 (18%)

Query: 79  AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
           A G+G AGG E +       +    S++KKLK+  +L+ L +A+ ++    T C+ +P  
Sbjct: 22  AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPST 80

Query: 132 LDCRLGPGAPAGAQPAQPPSSYS-------------------LP-LLLCKVFRWPDLRHS 171
                G   P           YS                   LP ++ C+++RWPDL   
Sbjct: 81  CSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSH 140

Query: 172 SEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP-------------PPYSRY---- 214
            E+K +  CE    +  + VC NP+H  R+     PP             PP   Y    
Sbjct: 141 HELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSI 200

Query: 215 ---------------------PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQ 250
                                P  ++    +  D  +  S +TG    L+P  LS  +  
Sbjct: 201 PENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHS 260

Query: 251 LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDN 305
           L L+P    + + WC +AY+E   RVG  +   +PSL  D F D      FCLG L++ N
Sbjct: 261 LDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVN 320

Query: 306 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGF 364
           ++  V+  R  IG G++L      V+    S   IF++S   +         V K+ PG 
Sbjct: 321 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 380

Query: 365 SIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
           ++K F+ ++  +L  Q  N   E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 381 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 440

Query: 422 IFN 424
             N
Sbjct: 441 HLN 443


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  119 bits (299), Expect = 4e-27
 Identities = 108/375 (28%), Positives = 163/375 (43%), Gaps = 62/375 (16%)

Query: 98  SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
           S++KKLK+++  +  L+   S  G  + C+ +P  LD RL           Q      LP
Sbjct: 40  SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88

Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL-------------- 201
            ++ C+V+RWPDL+   E+K L CCE       + VC NP+H  R+              
Sbjct: 89  HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148

Query: 202 --------------CELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241
                           L S P  P  + YP  F +P        PS A +      +Y  
Sbjct: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208

Query: 242 APGGLSDSQLLLEPGD--------RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLP 291
           +PG  S+ +   +  D          HWC VAY+E   RVG  +     S  +D F D  
Sbjct: 209 SPGSPSEPESPYQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPS 268

Query: 292 QG-NGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNP 350
              N FCLG L++ N++  ++  R  IG G+ L      V+    S   IF++S   +  
Sbjct: 269 NNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQ 328

Query: 351 DS-RTLLVHKVFPGFSIKAFDYEKAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQC 406
                  V K+  G S+K F+ +    L   + H   E + +     T+++SFVKGWG  
Sbjct: 329 HGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAE 388

Query: 407 YTRQFISSCPCWLEV 421
           Y RQ ++S PCW+E+
Sbjct: 389 YHRQDVTSTPCWIEI 403


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  115 bits (288), Expect = 8e-26
 Identities = 88/316 (27%), Positives = 149/316 (47%), Gaps = 48/316 (15%)

Query: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYSR 213
           ++ C+++RWPDL    E++ +  CE    +  + VC NP+H  R+     PP   P ++ 
Sbjct: 42  VIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE 101

Query: 214 YPMDF-------------------LKPTADCPDAVPSS--AETG-------------GTN 239
            P +F                   ++P ++ P+  P    +E G             G+ 
Sbjct: 102 IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSP 161

Query: 240 YLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLPQ 292
            L+P  +S +   L L+P    + + WC ++Y+E   RVG  +   +PS+ +  F D   
Sbjct: 162 NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 221

Query: 293 GNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS 352
              FCLG L++ N++  V+  R  IG G++L      V+    S   IF++S   +    
Sbjct: 222 SERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYG 281

Query: 353 -RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYT 408
                V K+ PG ++K F+ ++  +L  Q  N   E + Q     T+++SFVKGWG  Y 
Sbjct: 282 WHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYR 341

Query: 409 RQFISSCPCWLEVIFN 424
           RQ ++S PCW+E+  N
Sbjct: 342 RQTVTSTPCWIELHLN 357


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  100 bits (248), Expect = 3e-21
 Identities = 110/412 (26%), Positives = 163/412 (39%), Gaps = 99/412 (24%)

Query: 98  SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
           S++KKLK+++  +  L+   S  G  + C+ +P  LD RL           Q      LP
Sbjct: 40  SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88

Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCN-----------------PHHL 198
            ++ C+V+RWPDL+   E+K L CCE       + VC N                 P H 
Sbjct: 89  HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148

Query: 199 S-----------RLCELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241
                       R   L S P  P  + YP  F +P        PS A +      +Y  
Sbjct: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208

Query: 242 APGGLSDSQ-------------------------------------LLLEPGD------- 257
           +PG  S+ +                                     L +  GD       
Sbjct: 209 SPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFRPVCYE 268

Query: 258 -RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLPQG-NGFCLGQLNSDNKSQLVQKV 313
              HWC VAY+E   RVG  +     S  +D F D     N FCLG L++ N++  ++  
Sbjct: 269 EPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENT 328

Query: 314 RSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYE 372
           R  IG G+ L      V+    S   IF++S   +         V K+  G S+K F+ +
Sbjct: 329 RRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQ 388

Query: 373 KAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
               L   + H   E + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 389 LFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 440


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 81/293 (27%), Positives = 134/293 (45%), Gaps = 48/293 (16%)

Query: 180 CESYGKINPELVCCNPHHLSRLCELESPP---PPYSRYPMDF------------------ 218
           CE    +  + VC NP+H  R+     PP   P ++  P +F                  
Sbjct: 4   CEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPA 63

Query: 219 -LKPTADCPDAVPSS--AETG-------------GTNYLAPGGLSDSQ--LLLEPG---D 257
            ++P ++ P+  P    +E G             G+  L+P  +S +   L L+P    +
Sbjct: 64  GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCE 123

Query: 258 RSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315
            + WC ++Y+E   RVG  +   +PS+ +  F D      FCLG L++ N++  V+  R 
Sbjct: 124 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 183

Query: 316 KIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKA 374
            IG G++L      V+    S   IF++S   +         V K+ PG ++K F+ ++ 
Sbjct: 184 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 243

Query: 375 YSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424
            +L  Q  N   E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+  N
Sbjct: 244 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 296


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 111/417 (26%), Positives = 171/417 (41%), Gaps = 107/417 (25%)

Query: 98  SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
           +++KKLK+++  +E L +A+ S  G  + C+ +P  LD RL           Q      L
Sbjct: 36  ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRL-----------QVSHRKGL 83

Query: 156 P-LLLCKVFRWPDLRHSSEVKRL-CCCESYGKINPELVCC-------------------- 193
           P ++ C+V+RWPDL+   E+K L CC   +G    E VC                     
Sbjct: 84  PHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE-VCINPYHYKRVESPVLPPVLVPR 142

Query: 194 ----NPHHLSRLCELES--------------------------PPPPYSRYPMDFLKPTA 223
               NP H S L +  +                          P  P S YP      ++
Sbjct: 143 HSEYNPQH-SLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSS 201

Query: 224 DCPDAVPSS---------AETGGTNYLAP--------GGLSDSQLLLEP-------GD-- 257
             P +  SS         A+T    YL P            D+ ++  P       GD  
Sbjct: 202 TYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQ 261

Query: 258 ------RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQG-NGFCLGQLNSDNKSQ 308
                   HWC + Y+E   RVG  +     S+  D F D     N FCLG L++ N++ 
Sbjct: 262 AVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNS 321

Query: 309 LVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIK 367
            ++  R  IG G+ L      V+    S   IF++S   + +       V K+  G S+K
Sbjct: 322 TIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLK 381

Query: 368 AFDYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
            F+ ++ A  L +  +H F  + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 382 IFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 111/417 (26%), Positives = 171/417 (41%), Gaps = 107/417 (25%)

Query: 98  SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
           +++KKLK+++  +E L +A+ S  G  + C+ +P  LD RL           Q      L
Sbjct: 36  ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRL-----------QVSHRKGL 83

Query: 156 P-LLLCKVFRWPDLRHSSEVKRL-CCCESYGKINPELVCC-------------------- 193
           P ++ C+V+RWPDL+   E+K L CC   +G    E VC                     
Sbjct: 84  PHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE-VCINPYHYKRVESPVLPPVLVPR 142

Query: 194 ----NPHHLSRLCELES--------------------------PPPPYSRYPMDFLKPTA 223
               NP H S L +  +                          P  P S YP      ++
Sbjct: 143 HSEYNPQH-SLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSS 201

Query: 224 DCPDAVPSS---------AETGGTNYLAP--------GGLSDSQLLLEP-------GD-- 257
             P +  SS         A+T    YL P            D+ ++  P       GD  
Sbjct: 202 TYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQ 261

Query: 258 ------RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQG-NGFCLGQLNSDNKSQ 308
                   HWC + Y+E   RVG  +     S+  D F D     N FCLG L++ N++ 
Sbjct: 262 AVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNS 321

Query: 309 LVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIK 367
            ++  R  IG G+ L      V+    S   IF++S   + +       V K+  G S+K
Sbjct: 322 TIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLK 381

Query: 368 AFDYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
            F+ ++ A  L +  +H F  + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 382 IFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)

Query: 98  SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
           +++KKLK+++  +E L +A+ S G   + C+ +P  LD RL           Q      L
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84

Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
           P ++ C+V+RWPDL+   E+K L  CE       + VC                      
Sbjct: 85  PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144

Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
              NP H        L   E   P  + +P  F         L P +  P +  SS    
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204

Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
                         A+T    Y+ P    G  +SQ +                  ++P  
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264

Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
             +  HWC + Y+E   RVG  +     S+  D F D P  N   FCLG L++ N++  +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323

Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
           +  R  IG G+ L      V+    S   IF++S   + +       V K+    S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383

Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
           + ++ A  L +  +H F  + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)

Query: 98  SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
           +++KKLK+++  +E L +A+ S G   + C+ +P  LD RL           Q      L
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84

Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
           P ++ C+V+RWPDL+   E+K L  CE       + VC                      
Sbjct: 85  PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144

Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
              NP H        L   E   P  + +P  F         L P +  P +  SS    
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204

Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
                         A+T    Y+ P    G  +SQ +                  ++P  
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264

Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
             +  HWC + Y+E   RVG  +     S+  D F D P  N   FCLG L++ N++  +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323

Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
           +  R  IG G+ L      V+    S   IF++S   + +       V K+    S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383

Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
           + ++ A  L +  +H F  + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)

Query: 98  SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
           +++KKLK+++  +E L +A+ S G   + C+ +P  LD RL           Q      L
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84

Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
           P ++ C+V+RWPDL+   E+K L  CE       + VC                      
Sbjct: 85  PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144

Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
              NP H        L   E   P  + +P  F         L P +  P +  SS    
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204

Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
                         A+T    Y+ P    G  +SQ +                  ++P  
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264

Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
             +  HWC + Y+E   RVG  +     S+  D F D P  N   FCLG L++ N++  +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323

Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
           +  R  IG G+ L      V+    S   IF++S   + +       V K+    S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383

Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
           + ++ A  L +  +H F  + +     T+++SFVKGWG  Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 232 SAETGGTNYLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI 286
           S + G  N L+P  +S +   L L+P    + + WC ++Y+E   RVG  +   +PS+ +
Sbjct: 4   SMDAGSPN-LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 62

Query: 287 --FYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKS 344
             F D      FCLG L++ N++  V+  R  IG G++L      V+    S   IF++S
Sbjct: 63  DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 122

Query: 345 ATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFV 400
              +         V K+ PG ++K F+ ++  +L  Q  N   E + Q     T+++SFV
Sbjct: 123 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 182

Query: 401 KGWGQCYTRQFISSCPCWLEVIFN 424
           KGWG  Y RQ ++S PCW+E+  N
Sbjct: 183 KGWGAEYRRQTVTSTPCWIELHLN 206


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 62/214 (28%), Positives = 95/214 (44%), Gaps = 60/214 (28%)

Query: 260 HWCVVAYWEEKTRVGRLYCVQEP----SLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315
           +WC +AY+E   +VG  + V       ++D + D   G+ FCLGQL++ ++++ +++ R 
Sbjct: 322 YWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARL 381

Query: 316 KIGCGIQLTREVDG-VWVYNRSSYPIFIKSATLDNPDSRTL--LVHKVFPGFSIKAFDYE 372
            IG G+QL  + +G VWV   S + +F++S  LD    R     VHK++P   IK FD  
Sbjct: 382 HIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLR 441

Query: 373 KAYSLQRPNDHEFMQQ--------------------PWTGFT------------------ 394
           +         H  MQQ                    P  G                    
Sbjct: 442 QC--------HRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVD 493

Query: 395 -------VQISFVKGWGQCYTRQFISSCPCWLEV 421
                  +++SFVKGWG  Y RQ I   PCW+E+
Sbjct: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEI 527



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 13/118 (11%)

Query: 86  GGAEADLKALTHSVLKKLKERQLEL--LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAG 143
           G +E   K    S++KKLKE++ EL  L+ A+ + G   + C+ +   LD RL      G
Sbjct: 30  GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKG 89

Query: 144 AQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL 201
                        ++  +++RWPDL H +E+K +  C+    +  + VC NP+H  R+
Sbjct: 90  FPH----------VIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYERV 136


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 18  APGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHP 77
           A GG    +G GGGGG G   G G       G GGGGPG  G   G  + G   H HPH 
Sbjct: 137 AAGGGGAHDGPGGGGGPG---GGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHM 193

Query: 78  PAAG 81
            + G
Sbjct: 194 HSLG 197


>gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a
           [Homo sapiens]
          Length = 589

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 21/89 (23%)

Query: 11  RRLWRSRAPGGEDEEEGA-------GGGGGGGELRGEGATDSRA------------HGAG 51
           RRL + + P  +    GA       GGGGGGG   G G+   RA            HG G
Sbjct: 14  RRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG 73

Query: 52  GGGPGRAGCCLGKAVRGAKGHHHPHPPAA 80
           GGG G AG   G    G + +  PH   A
Sbjct: 74  GGGGGGAGAAGGGG--GGENYDDPHKTPA 100


>gi|4503119 cancer/testis antigen 1B [Homo sapiens]
          Length = 180

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 24  EEEGAGGGGGGGELRGEGATD-SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGA 82
           + EG G GG  G+  G G        G   GGPG AG   G+  RGA G      P  GA
Sbjct: 2   QAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGA-GAARASGPGGGA 60

Query: 83  --GAAGGAEADLKALTHSVLKKLKERQLELLL 112
             G  GGA + L        +  + R LE  L
Sbjct: 61  PRGPHGGAASGLNGCCRCGARGPESRLLEFYL 92



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 11/52 (21%)

Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP---------GRAGCC 61
          PGG     G  G  GG   RG GA  +RA G GGG P         G  GCC
Sbjct: 27 PGGNAGGPGEAGATGGRGPRGAGA--ARASGPGGGAPRGPHGGAASGLNGCC 76


>gi|21281685 cancer/testis antigen 1A [Homo sapiens]
          Length = 180

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 24  EEEGAGGGGGGGELRGEGATD-SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGA 82
           + EG G GG  G+  G G        G   GGPG AG   G+  RGA G      P  GA
Sbjct: 2   QAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGA-GAARASGPGGGA 60

Query: 83  --GAAGGAEADLKALTHSVLKKLKERQLELLL 112
             G  GGA + L        +  + R LE  L
Sbjct: 61  PRGPHGGAASGLNGCCRCGARGPESRLLEFYL 92



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 11/52 (21%)

Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP---------GRAGCC 61
          PGG     G  G  GG   RG GA  +RA G GGG P         G  GCC
Sbjct: 27 PGGNAGGPGEAGATGGRGPRGAGA--ARASGPGGGAPRGPHGGAASGLNGCC 76


>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 27/60 (45%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 27  GAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGH---HHPHPPAAGAG 83
           GAGGGGGG      GA    A GAGGGG G  G    +   GA G    H+  P  AG G
Sbjct: 324 GAGGGGGG----AVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGG 379



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 9/88 (10%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAG-----GGGPGRAGCCLGKAVRGAKGHHH 74
           GG     G GGGGGG    G GA   R   +G        P  AG  +   V G      
Sbjct: 337 GGAAGGAGGGGGGGG----GAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPA 392

Query: 75  PHPPAAGAGAAGGAEADLKALTHSVLKK 102
           P PPA  A A G    +  A   + L +
Sbjct: 393 PAPPAPSAPAPGTLAKEAAASNTNTLNR 420



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 21/101 (20%)

Query: 2   FRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGG-----------GELRGEGATDSRAHGA 50
           FR +R +  R   RS  P    +    G GG G                +G+  +   GA
Sbjct: 268 FRYRRRS--RSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGA 325

Query: 51  GGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAEAD 91
           GGGG G  G   G A  GA G         G G   GAE D
Sbjct: 326 GGGGGGAVG-AFGGAAGGAGG-------GGGGGGGAGAERD 358


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 11/84 (13%)

Query: 16  SRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGG--------PGRAGCCLGKAVR 67
           S  PG + ++   GG GGGG   G G   S A G GGG         P +   C  K   
Sbjct: 148 SSKPGEKGDK--VGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAG 205

Query: 68  GAKGH-HHPHPPAAGAGAAGGAEA 90
           GA G    PH     AG  GG +A
Sbjct: 206 GAGGGVSKPHAKLILAGGGGGGKA 229



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 43/158 (27%), Positives = 52/158 (32%), Gaps = 28/158 (17%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATD----SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHP 75
           GG     G GGG  GG    + A      S+  G  GGG  +    L  A  G  G    
Sbjct: 172 GGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAA 231

Query: 76  HPPAAGAGAAGGAEADL---KALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR- 131
              A+ A    GA A L    A  H  L K +         A  S   + +A L  PG+ 
Sbjct: 232 AAAASFAAEQAGAAALLPLGAAADHHSLYKARTPS----ASASASSAASASAALAAPGKH 287

Query: 132 --------------LDCRLGP--GAPAGAQPAQPPSSY 153
                         L     P  G  AGA P+ P   Y
Sbjct: 288 LAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLY 325


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 3/77 (3%)

Query: 14  WRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGG---GGPGRAGCCLGKAVRGAK 70
           W+ R  GG       GGGGGGG   G G       G GG   GG G  G   G    G +
Sbjct: 325 WQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGR 384

Query: 71  GHHHPHPPAAGAGAAGG 87
           G         G G  GG
Sbjct: 385 GGFQGRGDYGGRGGYGG 401



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 23/61 (37%), Positives = 27/61 (44%)

Query: 27  GAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAG 86
           G GGGGGGG   G G    R    G G  G  G   G+   G +G+  P+    G G  G
Sbjct: 365 GWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGG 424

Query: 87  G 87
           G
Sbjct: 425 G 425



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 5/69 (7%)

Query: 19  PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPP 78
           P  +  +EG GG GG G   G G       G GGGG GR G   G    G  G       
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGG-----GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG 377

Query: 79  AAGAGAAGG 87
             G G  GG
Sbjct: 378 GGGGGGRGG 386



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 17/39 (43%), Positives = 18/39 (46%)

Query: 21  GEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAG 59
           G  +  G GG GG G   G G  D    G GGGG G  G
Sbjct: 389 GRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 3/49 (6%)

Query: 14  WRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHG---AGGGGPGRAG 59
           W     GG    +G G  GG G   G G    R +G    GGGG G  G
Sbjct: 376 WGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGG 424


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 44/142 (30%), Positives = 55/142 (38%), Gaps = 38/142 (26%)

Query: 30  GGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAE 89
           GGGGGG   G         G+ GGGPG  G        G  G + P+  AA A AA  A 
Sbjct: 77  GGGGGGSAGG---------GSSGGGPGGGG--------GGAGGYAPYYAAAAAAAAAAAA 119

Query: 90  ADLKALTHSVLKKLKERQLELLLQAVE--------SRGGTRTACL---------LLPGRL 132
           A+  A+   +L     R  ++L +A E          G    A           +LP   
Sbjct: 120 AEEAAMQRELLPPAGRRP-DVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGF 178

Query: 133 D--CRLGPGAP-AGAQPAQPPS 151
           D      PG P AG QP  PP+
Sbjct: 179 DQFYEAAPGPPFAGPQPPPPPA 200



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 23  DEEEGAGGGGGGGELRGEGATDSR--AHGAGGGG---PGRAG 59
           D   GAGGGGG    +    ++ +  A G+GG G   PG AG
Sbjct: 212 DPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAG 253


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/67 (38%), Positives = 27/67 (40%), Gaps = 4/67 (5%)

Query: 21  GEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAA 80
           G    EG GGG G G    EG   S     GGGG  R     G  + G  GH     P  
Sbjct: 766 GHRPHEGPGGGMGSGHRPHEGPGGSM----GGGGGHRPHEGPGGGISGGSGHRPHEGPGG 821

Query: 81  GAGAAGG 87
           G GA GG
Sbjct: 822 GMGAGGG 828



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 3/73 (4%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPA 79
           GG    EG GGG  GG   G    +    G G GG  R     G ++ G+ G H PH   
Sbjct: 795 GGHRPHEGPGGGISGGS--GHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS-GGHRPHEGP 851

Query: 80  AGAGAAGGAEADL 92
              G  G    D+
Sbjct: 852 GHGGPHGHRPHDV 864



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 14/68 (20%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPA 79
           GG+   +G G    GG +RG            G GPG      G+  RG  G+  P PP 
Sbjct: 675 GGDPFWDGPGDPMRGGPMRG------------GPGPGPGPYHRGRGGRG--GNEPPPPPP 720

Query: 80  AGAGAAGG 87
              GA GG
Sbjct: 721 PFRGARGG 728



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 23/71 (32%), Positives = 25/71 (35%), Gaps = 4/71 (5%)

Query: 19  PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP--GRAGCCLGKAVRGAKGHHHPH 76
           PG      G GG GG               G  GGGP  GR G   G  + G  GH    
Sbjct: 698 PGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGG--PGGGMVGGGGHRPHE 755

Query: 77  PPAAGAGAAGG 87
            P  G G + G
Sbjct: 756 GPGGGMGNSSG 766



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 7/60 (11%)

Query: 29  GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
           GG  GGG   G G       G GGG  G  G    +   G  G+   H P  G G   G+
Sbjct: 727 GGRSGGGPPNGRG-------GPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS 779



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 12/84 (14%)

Query: 16  SRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGG----GGPGRAGCCLGKA--VRGA 69
           S   G    E   GG G GG  R          G+GG     GPG  G    +   V G 
Sbjct: 808 SGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGH 867

Query: 70  KGHHHPHPPA------AGAGAAGG 87
           +GH H  PP        G G  GG
Sbjct: 868 RGHDHRGPPPHEHRGHDGPGHGGG 891



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 5/60 (8%)

Query: 30  GGGGGGELRGEGATDSRAH-GAGGGGPGRAGCCLGKAVRGAKGH-HHPHPPAAGAGAAGG 87
           GG GGG + G G    R H G GGG    +G    +   G  G  H PH    G+   GG
Sbjct: 739 GGPGGGMVGGGG---HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG 795


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)

Query: 29  GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
           GGGGGGG   G G++ +   G GGGG       L  A  G+ G         G  +AGG 
Sbjct: 75  GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127

Query: 89  EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
            A    +  S               +  S   + ++C  LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
           GG     G GGGGGGG         + ++G+GGGG G
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)

Query: 20  GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
           GG     G GGGGGGG       A  S   G GGGG    G
Sbjct: 86  GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)

Query: 29  GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
           GGGGGGG   G G++ +   G GGGG       L  A  G+ G         G  +AGG 
Sbjct: 75  GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127

Query: 89  EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
            A    +  S               +  S   + ++C  LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
           GG     G GGGGGGG         + ++G+GGGG G
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)

Query: 20  GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
           GG     G GGGGGGG       A  S   G GGGG    G
Sbjct: 86  GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)

Query: 29  GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
           GGGGGGG   G G++ +   G GGGG       L  A  G+ G         G  +AGG 
Sbjct: 75  GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127

Query: 89  EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
            A    +  S               +  S   + ++C  LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 20  GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
           GG     G GGGGGGG         + ++G+GGGG G
Sbjct: 85  GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)

Query: 20  GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
           GG     G GGGGGGG       A  S   G GGGG    G
Sbjct: 86  GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,942,882
Number of Sequences: 37866
Number of extensions: 1207913
Number of successful extensions: 13067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 310
Number of HSP's that attempted gapping in prelim test: 7717
Number of HSP's gapped (non-prelim): 3239
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press