Search of human proteins with 51477692

Search of human proteins with 51477692

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51477692 tripartite motif-containing 6 isoform 1 [Homo
sapiens]
         (516 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]   1064   0.0  
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]   1011   0.0  
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   665   0.0  
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      563   e-160
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      563   e-160
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            547   e-155
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   531   e-151
gi|15208660 tripartite motif protein 21 [Homo sapiens]                400   e-111
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...   383   e-106
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...   383   e-106
gi|37622899 ring finger protein 137 [Homo sapiens]                    342   4e-94
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]     328   9e-90
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            310   3e-84
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              295   5e-80
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             287   2e-77
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   272   6e-73
gi|5730009 ret finger protein [Homo sapiens]                          268   1e-71
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   262   5e-70
gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]      253   2e-67
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   234   1e-61
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    234   1e-61
gi|22749269 ring finger protein 129 [Homo sapiens]                    226   4e-59
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             221   1e-57
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            218   1e-56
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   214   1e-55
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   213   3e-55
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    206   4e-53
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   201   2e-51
gi|4557743 Mediterranean fever protein [Homo sapiens]                 199   7e-51
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   198   9e-51

>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 1064 bits (2751), Expect = 0.0
 Identities = 516/516 (100%), Positives = 516/516 (100%)

Query: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60
           MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH
Sbjct: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60

Query: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120
           SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL
Sbjct: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120

Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180
           KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK
Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180

Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240
           NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG
Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240

Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300
           LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT
Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300

Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSG 360
           KLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSG
Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSG 360

Query: 361 PSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAY 420
           PSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAY
Sbjct: 361 PSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAY 420

Query: 421 SRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNH 480
           SRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNH
Sbjct: 421 SRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNH 480

Query: 481 GFPIYTFSKYYFPTTLCPYFNPCNCVIPMTLRRPSS 516
           GFPIYTFSKYYFPTTLCPYFNPCNCVIPMTLRRPSS
Sbjct: 481 GFPIYTFSKYYFPTTLCPYFNPCNCVIPMTLRRPSS 516


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score = 1011 bits (2614), Expect = 0.0
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ
Sbjct: 1   MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
           TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE
Sbjct: 61  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
           CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
           CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300

Query: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 388
           VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD
Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360

Query: 389 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 448
           VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP
Sbjct: 361 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 420

Query: 449 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 508
           SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP
Sbjct: 421 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVIP 480

Query: 509 MTLRRPSS 516
           MTLRRPSS
Sbjct: 481 MTLRRPSS 488


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  665 bits (1716), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60
           MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH
Sbjct: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60

Query: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120
           SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL
Sbjct: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120

Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180
           KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK
Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180

Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240
           NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG
Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240

Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300
           LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT
Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300

Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328
           KLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328



 Score =  563 bits (1452), Expect = e-160
 Identities = 294/496 (59%), Positives = 361/496 (72%), Gaps = 12/496 (2%)

Query: 27  ATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPV 86
           + M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPV
Sbjct: 353 SAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPV 412

Query: 87  CQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146
           C  SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWL
Sbjct: 413 CGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWL 472

Query: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206
           CERSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ 
Sbjct: 473 CERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQT 532

Query: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266
           ER RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E
Sbjct: 533 ERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVE 592

Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 326
            R Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ 
Sbjct: 593 CRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRC 652

Query: 327 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWE 386
           YWVDVTLN    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWE
Sbjct: 653 YWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWE 706

Query: 387 VDVAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYE 444
           VDV+KKTAWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E
Sbjct: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFE 766

Query: 445 DSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
           +S  S    L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYF
Sbjct: 767 ESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826

Query: 501 NPCNCVIPMTLRRPSS 516
           NP NC  PMTL  PSS
Sbjct: 827 NPWNCPAPMTLCPPSS 842


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  563 bits (1451), Expect = e-160
 Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 388
           VDVTLN    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 354

Query: 389 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 446
           V+KKTAWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E+S
Sbjct: 355 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 414

Query: 447 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 502
             S    L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYFNP
Sbjct: 415 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 474

Query: 503 CNCVIPMTLRRPSS 516
            NC  PMTL  PSS
Sbjct: 475 WNCPAPMTLCPPSS 488


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  563 bits (1451), Expect = e-160
 Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 388
           VDVTLN    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 354

Query: 389 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 446
           V+KKTAWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E+S
Sbjct: 355 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 414

Query: 447 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 502
             S    L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYFNP
Sbjct: 415 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 474

Query: 503 CNCVIPMTLRRPSS 516
            NC  PMTL  PSS
Sbjct: 475 WNCPAPMTLCPPSS 488


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  547 bits (1409), Expect = e-155
 Identities = 287/501 (57%), Positives = 355/501 (70%), Gaps = 16/501 (3%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M   V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT   +ESVI   GE SCPVCQ
Sbjct: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
           T +QPGNLRPNRHLANIV R++EV + P +  K  +C  HG+KLQ+FC+EDGKVICW+CE
Sbjct: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
            SQEH+GH TF + EV +E QEK Q +L++L  E+QEAEKL   IR+++T+WKN ++ ER
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            +I   FN++R ILD  EQREL+KLE+ E   L  +  A + LV Q Q    LISDL+RR
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            +GS++E+LQDV DV +RSE WTL+KP+++  KL+S+FR PDL  ML+V +ELTDVQ YW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300

Query: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGA---KVSGPSCLEKHYDCSVLGSQHFSSGKHYW 385
           VDV LNP +A  N+ ++ ++RQV+ V     K S P          V G Q+FSSGK+YW
Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAF---GVFGCQYFSSGKYYW 357

Query: 386 EVDVAKKTAWILGVCS--NSLGPT----FSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 439
           EVDV+ K AWILGV S  +SL       F+F+        YSRY+PQ GYWVIGLQ+  E
Sbjct: 358 EVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCE 417

Query: 440 YRAYEDSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 495
           Y A+EDSS S    L L M VPP R+GVFLDYEAG VSF+NVTNHG  IY FS   F   
Sbjct: 418 YNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRP 477

Query: 496 LCPYFNPCNCVIPMTLRRPSS 516
             PYFNP NC++PMT+  PSS
Sbjct: 478 AYPYFNPWNCLVPMTVCPPSS 498


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  531 bits (1367), Expect = e-151
 Identities = 281/502 (55%), Positives = 353/502 (70%), Gaps = 23/502 (4%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+AN+V +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTF  EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298

Query: 329 VDVTLNPHTANLNLVLAKNRRQVR------FVGAK-VSGPSCLEKHYDCSVLGSQHFSSG 381
           VDVT+ P+  +   V+++++RQV         GA+     + +  +Y   +LGSQ  +SG
Sbjct: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357

Query: 382 KHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYR 441
           KHYWEVDV+KKTAWILGVC+              N      YQP+ GYWVIGL+   +  
Sbjct: 358 KHYWEVDVSKKTAWILGVCAGFQPDAMC------NIEKNENYQPKYGYWVIGLEEGVKCS 411

Query: 442 AYEDSS---PS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 494
           A++DSS   PS    + LS+ + P RVGVFLDYEA TVSF+N+TNHGF IY FS   F  
Sbjct: 412 AFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQ 471

Query: 495 TLCPYFNPCNCVIPMTLRRPSS 516
            + PY NP  C +PMTL  PSS
Sbjct: 472 PVFPYLNPRKCGVPMTLCSPSS 493


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  400 bits (1029), Expect = e-111
 Identities = 215/466 (46%), Positives = 294/466 (63%), Gaps = 31/466 (6%)

Query: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 98
           EEVTCPICL+   EP+SI+CGHSFCQ CI      S +G+ G   CPVC+  +   NLRP
Sbjct: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65

Query: 99  NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 158
           NR LAN+V  L+E+     +  +   CA HGE+L LFC++DGK +CW+C +S++HR H  
Sbjct: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125

Query: 159 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 218
             +EE AQEYQEK Q +L +L+ +++ AEKL   I  K+  WK  +E ++ RI  EF Q 
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185

Query: 219 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 278
           +N L   EQR+L++LE++E++ LRI+ E E  L  Q+Q+L+ELIS+L+RRC  S +ELLQ
Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245

Query: 279 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTA 338
           +V  V ERSE W L+  +    +LRS+   P LK+MLR C          V +TL+P TA
Sbjct: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296

Query: 339 NLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWI 396
           N  L+L+++RRQVR    + S P   E+ +D    VLG+QHF SGKHYWEVDV  K AW 
Sbjct: 297 NPWLILSEDRRQVRLGDTQQSIPG-NEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWD 355

Query: 397 LGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTV 456
           LGVC +S+               +     +SG+W I L +  +Y A   + P   L + V
Sbjct: 356 LGVCRDSV-----------RRKGHFLLSSKSGFWTIWLWNKQKYEA--GTYPQTPLHLQV 402

Query: 457 PPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 502
           PP +VG+FLDYEAG VSFYN+T+HG  IY+FS+  F   L P+F+P
Sbjct: 403 PPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSP 448


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score =  383 bits (984), Expect = e-106
 Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+ANIV +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score =  383 bits (984), Expect = e-106
 Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+ANIV +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  342 bits (878), Expect = 4e-94
 Identities = 185/478 (38%), Positives = 281/478 (58%), Gaps = 33/478 (6%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           I EEV CPIC+  L EP+SIDCGHSFC +C++         Q    +CP+C+   QP NL
Sbjct: 10  IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69

Query: 97  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156
           RPN  LAN+V ++R + L PG  LK  LC  HGEKL++FC+ED  ++C  C +S EH  H
Sbjct: 70  RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129

Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216
               +E+VA EY+ +  E+L+ LK E++EA KL    R++  +WK Q+E  +  I  EF 
Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189

Query: 217 QLRNILDRVE----------QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266
           + + +L++ +             L  L++E  + ++ +E   ++L+ Q+Q L  +I++L+
Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249

Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 326
            R Q     +LQD+ +V  RS+ W+L++PE +  +L++  R   L+ +L+         +
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILK---------T 300

Query: 327 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS-VLGSQHFSSGKHYW 385
           Y  DV L+P TA   L+++++R++V +       P   E+ Y  + VLGSQ  SSG+HYW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360

Query: 386 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 445
           EV+V  ++ W LGVC  ++           +        P  G+WVI L+  +EYRA  D
Sbjct: 361 EVEVGDRSEWGLGVCKQNV-----------DRKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409

Query: 446 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPC 503
             P  +LS+ VPPRRVG+F+DYEA  +SFYNVT+ G  I+TF +Y FP  L PYF+PC
Sbjct: 410 EYP--ILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPC 465


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score =  328 bits (840), Expect = 9e-90
 Identities = 165/255 (64%), Positives = 199/255 (78%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDV 283
            Q STMELLQD+S +
Sbjct: 241 SQWSTMELLQDMSGI 255


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  310 bits (793), Expect = 3e-84
 Identities = 180/479 (37%), Positives = 272/479 (56%), Gaps = 32/479 (6%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           +RE+  CP+CL+ L EP+S+DCGHSFC  CI+    +S   Q G  +CP C+  ++P   
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 97  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156
           RPNR LA +V  +R + LG G   +   CA HGE L  FC+ED   +CW+C+   EHR H
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127

Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216
            T  ++E A  YQ K Q +L+ ++ E ++A    A + +K   WK ++E +R R + EF 
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187

Query: 217 QLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMEL 276
           + R  L + EQR+L++LE EE+  L+ + E+++ LV Q+++L+EL  +L+ RCQ   + L
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247

Query: 277 LQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPH 336
           L+ V  V  RS+  T  + E +P +L++    P  + +LR          + VDV L+P 
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLR---------KFQVDVKLDPA 298

Query: 337 TANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLGSQHFSSGKHYWEVDVAKKTA 394
           TA+ +L+L  + R V+        P+  E+   + C +LG Q FSSG+HYWEV V +   
Sbjct: 299 TAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPC-ILGLQSFSSGRHYWEVLVGEGAE 357

Query: 395 WILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSM 454
           W LGVC ++L                +   P++G W + L   +EY     +SPS+ L  
Sbjct: 358 WGLGVCQDTL-----------PRKGETTPSPENGVWALWLLKGNEYMVL--ASPSVPLLQ 404

Query: 455 TVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNC---VIPMT 510
              PR +G+FLDYEAG +SFYNVT+ G  IYTF++  F   L PYF  C+    ++P T
Sbjct: 405 LESPRCIGIFLDYEAGEISFYNVTD-GSYIYTFNQ-LFSGLLRPYFFICDATPLILPPT 461


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  295 bits (756), Expect = 5e-80
 Identities = 177/471 (37%), Positives = 263/471 (55%), Gaps = 41/471 (8%)

Query: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 95
           EE TC ICL L+T P+SI+CGHS+C  CIT    N  +  + QE    CP C+  +   +
Sbjct: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70

Query: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
           LRPN+ L +++  L+E         + + C +HGE+  LFC+++G++ICW CER+ +H+G
Sbjct: 71  LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123

Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
           H T LVE+V Q Y+EK Q+++ KLK  E    +       + T WK +++ +R +I+++F
Sbjct: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183

Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
             L+  L   E+  L +LE+EE++ L  + + E  L  ++  L+  I +LE +CQGS  +
Sbjct: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243

Query: 276 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLRVCRELTDVQSYWVDV 331
           LLQ+V+D   RS    L   EA+  +L +M        D+K+MLR         S+ V V
Sbjct: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR---------SHQVSV 294

Query: 332 TLNPHTANLNLVLAKNRRQVR--FVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDV 389
           TL+P TA+  L+L+++RRQV   +        S     + C VLG + F+SG+ Y+EVDV
Sbjct: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC-VLGCEGFTSGRRYFEVDV 353

Query: 390 AKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS 449
            + T W LGVC  ++                 + +PQSG+W + L     Y A   +SP 
Sbjct: 354 GEGTGWDLGVCMENV-----------QRGTGMKQEPQSGFWTLRLCKKKGYVAL--TSPP 400

Query: 450 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
             L +   P  VG+FLDYEAG VSFYN  N G  I+TF K  F  TL PYF
Sbjct: 401 TSLHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  287 bits (734), Expect = 2e-77
 Identities = 177/490 (36%), Positives = 266/490 (54%), Gaps = 37/490 (7%)

Query: 29  MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 87
           M +P L  +++EE TC ICL+  T+P+  DCGH+FC+ CI    R      EG  +CP C
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56

Query: 88  QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 147
           +      NLRPNR LA +    R   L P   +   +C  H E L  FC ++ +++C  C
Sbjct: 57  RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114

Query: 148 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 207
           ERS EH  H    +++ A++ + K ++SL+ L+ + Q+A    A   E    W+  +E +
Sbjct: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174

Query: 208 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 267
           R  +  EF +LR +L   EQ+ L++LE+EE + L  + E    L  Q+  L ELI++LE 
Sbjct: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234

Query: 268 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSY 327
           RCQ   + LLQD+ D   R +   L+ PE +P +LR++ R P L   LR  R        
Sbjct: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG------- 287

Query: 328 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYW 385
             DVTL+P TAN  L+L+++RR V+    + + P   E+ +D    VLG + F+SG+HYW
Sbjct: 288 --DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPER-FDPGPCVLGQERFTSGRHYW 344

Query: 386 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 445
           EV+V  +T+W LGVC  ++           N          +G+W++         +Y +
Sbjct: 345 EVEVGDRTSWALGVCRENV-----------NRKEKGELSAGNGFWILVF-----LGSYYN 388

Query: 446 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP-CN 504
           SS   L  +  PPRRVG+FLDYEAG +SFY+ T+ G  ++ F +  F  TL P F+P  +
Sbjct: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFSPLSS 447

Query: 505 CVIPMTLRRP 514
              PMT+ RP
Sbjct: 448 SPTPMTICRP 457


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  272 bits (695), Expect = 6e-73
 Identities = 174/504 (34%), Positives = 271/504 (53%), Gaps = 34/504 (6%)

Query: 20  QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79
           +AGA   A  T+  L +++ E +C +CLE L EP+ I+CGH+FC+ACIT    +     E
Sbjct: 8   EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61

Query: 80  GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139
            +  CPVC+ + +  +LRPNR L ++V   +++     K     LC  H E L LFC ED
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121

Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199
            + +C +C  S  HR H    +++  QEY+EK Q+ L+ L+ + QE  +  +   +K   
Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181

Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259
            K  +E  R +I  EF +L   LD  +Q  L +LE+EE+  L+ + E    L  + + L 
Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241

Query: 260 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCR 319
            L +++E +C  S  E+L+DV    E+ E     +  ++  +L   F   +  R     R
Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNF--SNFPRQYFALR 299

Query: 320 ELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSG-PSCLEK--HYDCSVLGSQ 376
           ++  ++    DVTL+P TA+ NLVL+++R+ V+FV  ++   P    +   Y C VL ++
Sbjct: 300 KI--LKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPC-VLATE 356

Query: 377 HFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQH 436
            F+SG+HYWEV+V  KT W +GVC +S+                    P++GYW + L +
Sbjct: 357 GFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPL-----------PETGYWRVRLWN 405

Query: 437 NHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTL 496
             +Y A   ++P   L + V P+RVG+FLDYEAGT+SFYNVT+    IYTF+   F   L
Sbjct: 406 GDKYAA--TTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSH-IYTFTD-TFTEKL 461

Query: 497 CPYFNP-----CNCVIPMTLRRPS 515
            P F P          P+T+R P+
Sbjct: 462 WPLFYPGIRAGRKNAAPLTIRPPT 485


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  268 bits (684), Expect = 1e-71
 Identities = 173/487 (35%), Positives = 256/487 (52%), Gaps = 43/487 (8%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           +++E TCP+CL+   EP+ +DCGH+ C AC+      +    E   SCP C+ ++   ++
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65

Query: 97  RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152
           RPNRHLAN+   V++LR E   GPG ++   +C  H E L+L+C+ED   IC +C+RS+E
Sbjct: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123

Query: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212
           HRGH    +EE  + ++E+ Q  L  LK  +   ++  A   + +    +  + ER +I 
Sbjct: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183

Query: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 272
            EF QL + L   E R L +LE+ +      I  A          L  LI+ LE + Q  
Sbjct: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243

Query: 273 TMELLQDVSDVTERSEFWTLRKPEALPTKL---------RSMFRAPDLKRM-------LR 316
           T ELLQD+ D   R+E   + +P   P  L         + +F    LK+        + 
Sbjct: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDME 303

Query: 317 VCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLG 374
             +EL + Q Y VDVTL+P TA  +L+L+ N RQVR+   +   P   E+   + C VLG
Sbjct: 304 KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC-VLG 362

Query: 375 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGL 434
           S  F +G+HYWEV+V  K  W +GVC +S+          +     S   PQ+G+W + L
Sbjct: 363 SPCFIAGRHYWEVEVGDKAKWTIGVCEDSV---------CRKGGVTS--APQNGFWAVSL 411

Query: 435 QHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 494
            +  EY A   +SP   L +  P +RVG+FLDY+AG VSFYNVT      +TFS   F  
Sbjct: 412 WYGKEYWAL--TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCG 468

Query: 495 TLCPYFN 501
            + PYF+
Sbjct: 469 PVRPYFS 475


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  262 bits (670), Expect = 5e-70
 Identities = 179/535 (33%), Positives = 277/535 (51%), Gaps = 66/535 (12%)

Query: 20  QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79
           +AGA   A  T+  L +++ E +C +CLE L EP+ I+CGH+FC+ACIT    +     E
Sbjct: 8   EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61

Query: 80  GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139
            +  CPVC+ + +  +LRPNR L ++V   +++     K     LC  H E L LFC ED
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121

Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199
            + +C +C  S  HR H    +++  QEY+EK Q+ L+ L+ + QE  +  +   +K   
Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181

Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259
            K  +E  R +I  EF +L   LD  +Q  L +LE+EE+  L+ + E    L  + + L 
Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241

Query: 260 ELISDLERRCQGSTMELLQDVSDVTERS-------EFWTL--RKPEALPTKLRSMFRAPD 310
            L +++E +C  S  E+L+DV    E++          T+  R  +AL   ++ + R   
Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEK 301

Query: 311 LKRMLRVCRELTDV------------QSYWV----------DVTLNPHTANLNLVLAKNR 348
           +K M     E+T V            + Y+           DVTL+P TA+ NLVL+++R
Sbjct: 302 VKTM-----EVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDR 356

Query: 349 RQVRFVGAKVSGPSCLEKH---YDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLG 405
           + V+FV  ++       +    Y C VL ++ F+SG+HYWEV+V  KT W +GVC +S+ 
Sbjct: 357 KSVKFVETRLRDLPDTPRRFTFYPC-VLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVS 415

Query: 406 PTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFL 465
                              P++GYW + L +  +Y A   ++P   L + V P+RVG+FL
Sbjct: 416 RKGELTPL-----------PETGYWRVRLWNGDKYAA--TTTPFTPLHIKVKPKRVGIFL 462

Query: 466 DYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP-----CNCVIPMTLRRPS 515
           DYEAGT+SFYNVT+    IYTF+   F   L P F P          P+T+R P+
Sbjct: 463 DYEAGTLSFYNVTDRSH-IYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515


>gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]
          Length = 243

 Score =  253 bits (647), Expect = 2e-67
 Identities = 136/249 (54%), Positives = 170/249 (68%), Gaps = 12/249 (4%)

Query: 274 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTL 333
           MELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YWVDVTL
Sbjct: 1   MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60

Query: 334 NPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKT 393
           N    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWEVDV+KKT
Sbjct: 61  NSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKT 114

Query: 394 AWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS-- 449
           AWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E+S  S  
Sbjct: 115 AWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDP 174

Query: 450 --LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPCNCVI 507
             L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYFNP NC  
Sbjct: 175 EVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPA 234

Query: 508 PMTLRRPSS 516
           PMTL  PSS
Sbjct: 235 PMTLCPPSS 243


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  234 bits (598), Expect = 1e-61
 Identities = 161/480 (33%), Positives = 245/480 (51%), Gaps = 49/480 (10%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90
           ++EE TC ICL+  T+P+   CGH+FC+ACI  +  E   G++G R       CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68

Query: 91  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
               NL PNR L  +    ++    PG Q K  LC +H E L+LFCQ+D   IC +C  S
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
           +EHR H     EE  Q Y+ K +E ++ L+ +      L A   +    W+ +++  R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I  EF ++   L   EQR L+ LE EE++    + E+   L  Q  SL  L+  LE R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWV 329
              +++LQD+ +   R    +++ PE A PT+ R++ R P    +LR          +  
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLE 295

Query: 330 DVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYW 385
           DV  +  +A   L+L ++ RQ R++G+   G     K     Y C+V G   FSSG+HYW
Sbjct: 296 DVVPDATSAYPYLLLYES-RQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYW 353

Query: 386 EV--DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY- 440
           EV  ++     W LGVC +             N S   R    P++G+WV+ L    +Y 
Sbjct: 354 EVGMNITGDALWALGVCRD-------------NVSRKDRVPKCPENGFWVVQLSKGTKYL 400

Query: 441 RAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
             +   +P +L+    PP  +G+FLD+EAG VSFY+V++ G  ++T+S+  FP  L P+F
Sbjct: 401 STFSALTPVMLME---PPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  234 bits (598), Expect = 1e-61
 Identities = 161/480 (33%), Positives = 245/480 (51%), Gaps = 49/480 (10%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90
           ++EE TC ICL+  T+P+   CGH+FC+ACI  +  E   G++G R       CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68

Query: 91  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
               NL PNR L  +    ++    PG Q K  LC +H E L+LFCQ+D   IC +C  S
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
           +EHR H     EE  Q Y+ K +E ++ L+ +      L A   +    W+ +++  R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I  EF ++   L   EQR L+ LE EE++    + E+   L  Q  SL  L+  LE R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWV 329
              +++LQD+ +   R    +++ PE A PT+ R++ R P    +LR          +  
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLE 295

Query: 330 DVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYW 385
           DV  +  +A   L+L ++ RQ R++G+   G     K     Y C+V G   FSSG+HYW
Sbjct: 296 DVVPDATSAYPYLLLYES-RQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYW 353

Query: 386 EV--DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY- 440
           EV  ++     W LGVC +             N S   R    P++G+WV+ L    +Y 
Sbjct: 354 EVGMNITGDALWALGVCRD-------------NVSRKDRVPKCPENGFWVVQLSKGTKYL 400

Query: 441 RAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
             +   +P +L+    PP  +G+FLD+EAG VSFY+V++ G  ++T+S+  FP  L P+F
Sbjct: 401 STFSALTPVMLME---PPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 456


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  226 bits (576), Expect = 4e-59
 Identities = 143/473 (30%), Positives = 247/473 (52%), Gaps = 33/473 (6%)

Query: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93
           LV+++EE +CPICLE L +P++I+CGH+FC++C++ + ++     +    CPVC+  +  
Sbjct: 7   LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDL----DDTFPCPVCRFCFPY 62

Query: 94  GNLRPNRHLANIVRRLREVVLGPGK---QLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
            + R N  L N+    +++ +   K   Q +  +C  H + L LFC +D +++C  C  S
Sbjct: 63  KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
            +H+ H+   +++ A  ++E  + SL+ L+N  +  EK+      K    K ++E +R  
Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I +EF Q+R  L   ++  L++++ EE   L  + E   +L     +L+ L+ ++E +  
Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPEALPTKLR--SMFRAPDLKRMLRVCRELTDVQSYW 328
            S +ELL     +    ++  L+ PE    +L        P    + R+      ++ + 
Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRI------IKPFQ 294

Query: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFSSGKHYWEV 387
           VDV L+ +TA+  L+++++R+ VR+   K +      + Y C +VLGSQ FSSG+HYWEV
Sbjct: 295 VDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEV 354

Query: 388 DVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSS 447
           +V  K  WILGVC + L       ++    S         G+W IG      Y A    +
Sbjct: 355 EVGNKPKWILGVCQDCL-----LRNWQDQPSVL------GGFWAIGRYMKSGYVASGPKT 403

Query: 448 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
             LL    V P ++G+FLDYE G +SFYN+ +    +YTF+   F   + PYF
Sbjct: 404 TQLL--PVVKPSKIGIFLDYELGDLSFYNMNDRSI-LYTFND-CFTEAVWPYF 452


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  221 bits (563), Expect = 1e-57
 Identities = 149/478 (31%), Positives = 245/478 (51%), Gaps = 36/478 (7%)

Query: 30  TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 89
           T+ ++ ++REE+TC ICL+  + P++ +CGHSFC  C+  +  E         SCP C  
Sbjct: 3   TADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE----HNTPLSCPECWR 58

Query: 90  SYQPGNLRPNRHL---ANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146
           + +  + + N  L   A+I R+LR  VL    +  +        K     ++ G      
Sbjct: 59  TLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV-- 116

Query: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206
              +Q H  +   L  E  + ++EK QE L  L+   +EA+ +    +E+    + + + 
Sbjct: 117 ---AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKT 173

Query: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266
            +  + +E+ ++   L   EQ +L+ LEQEEK+ +R +   E  L  Q +SL ++I+ +E
Sbjct: 174 CKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIE 233

Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 326
              Q S  E L++V    ERSE   L+ PEA  T+L S+ R   +K MLR          
Sbjct: 234 SSSQSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLR---------K 283

Query: 327 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVLGSQHFSSGKHYW 385
           +  ++TL+P TAN  LVL+++ + V++ G++   P   E+     +VLG+Q F+SG+HYW
Sbjct: 284 FSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYW 343

Query: 386 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 445
           EV+V  KT W +G+C +S+           +        P   + +IGL+   +Y  +  
Sbjct: 344 EVEVGNKTEWEVGICKDSV-----------SRKGNLPKPPGDLFSLIGLKIGDDYSLWV- 391

Query: 446 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNPC 503
           SSP     +  P  +VGVFLDYE+G ++FYN T+    IY+F +  F   L P F+PC
Sbjct: 392 SSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESL-IYSFPQASFQEALRPIFSPC 448


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  218 bits (555), Expect = 1e-56
 Identities = 140/472 (29%), Positives = 239/472 (50%), Gaps = 33/472 (6%)

Query: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93
           L  ++ E  C ICL+ L++P++I+CGH+FC++CI    ++S +  +    CPVC+   Q 
Sbjct: 7   LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62

Query: 94  GNLRPNRHLANIV---RRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
           G+ R N  L  ++   + L+       KQ +  LC  H + L +FC+ED  V+C LC + 
Sbjct: 63  GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
            +H+GHH   +E+ A  Y+++F   ++ LK +  + +KL +   +K    +  +E +R  
Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           + +EF  L   LDR +Q  L +L +EEK   + +        + + +L+  +S +    +
Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVD 330
            S +ELL  +  +   SE  +     ++  K       P    + R+      ++ + V+
Sbjct: 243 LSELELLSQIK-IFYESENESSPSIFSIHLKRDGCSFPPQYSALQRI------IKKFKVE 295

Query: 331 VTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYWEVD 388
           + L+P TA+ NL++++++++VRF   K   P    K +     VLG  +F SG+H+WE++
Sbjct: 296 IILDPETAHPNLIVSEDKKRVRFTKRKQKVPG-FPKRFTVKPVVLGFPYFHSGRHFWEIE 354

Query: 389 VAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSP 448
           V  K+ W +G+C +SL PT           A      Q   W I LQ +  +      +P
Sbjct: 355 VGDKSEWAIGICKDSL-PT----------KARRPSSAQQECWRIELQDDGYHAPGAFPTP 403

Query: 449 SLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
            LL    V  R +G+FLDYE G +SFYN+      I TF+   F   L PYF
Sbjct: 404 LLL---EVKARAIGIFLDYEMGEISFYNMAEKSH-ICTFTD-TFTGPLRPYF 450


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  214 bits (546), Expect = 1e-55
 Identities = 148/475 (31%), Positives = 235/475 (49%), Gaps = 55/475 (11%)

Query: 36  DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
           DI+EE+TCPICL+   +P+SI+CGH+FC+ C+  N         G   CP C+    P  
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60

Query: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
           LRPN  LA +  + +   LGP   +   LC  H E L+LFC++D + +C +C  SQEH+ 
Sbjct: 61  LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
           H    ++E  + Y+EK  +S + L  + ++   L     +  T WK++++ +R RI TEF
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177

Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
           ++L N L   E   L++L +EE++  + + E    L     SL++LI ++  + Q  T+E
Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237

Query: 276 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLN 334
           LLQ+  +V  RSE   +    EA+  K++++ + P +K ML+          + V V L 
Sbjct: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK---------RFQVAVNLA 286

Query: 335 PHTANLNLVLAKNRRQVRFVGAKVSGP------------------SCLEK--HYDCSVLG 374
             TA+  LV ++  R V+   +  S P                  + +E+  H  C VLG
Sbjct: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPC-VLG 345

Query: 375 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYW-VIG 433
              F+SGKHYWEV+        +GVC   +      +  + +   ++ Y   +GYW +IG
Sbjct: 346 KNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIG 405

Query: 434 LQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFS 488
                         P           RVGV+LD   G VSFY+  + G  ++TFS
Sbjct: 406 F-------------PGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS 446


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  213 bits (542), Expect = 3e-55
 Identities = 152/459 (33%), Positives = 231/459 (50%), Gaps = 49/459 (10%)

Query: 58  CGHSFCQACITPNGRESVIGQEGERS------CPVCQTSYQPGNLRPNRHLANIVRRLRE 111
           CGH+FC+ACI  +  E   G++G R       CP C+      NL PNR L  +    ++
Sbjct: 4   CGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQ 62

Query: 112 VVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEK 171
               PG Q K  LC +H E L+LFCQ+D   IC +C  S+EHR H     EE  Q Y+ K
Sbjct: 63  ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLK 118

Query: 172 FQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELK 231
            +E ++ L+ +      L A   +    W+ +++  R RI  EF ++   L   EQR L+
Sbjct: 119 LEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQ 178

Query: 232 KLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWT 291
            LE EE++    + E+   L  Q  SL  L+  LE R     +++LQD+ +   R    +
Sbjct: 179 ALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVS 238

Query: 292 LRKPE-ALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQ 350
           ++ PE A PT+ R++ R P    +LR          +  DV  +  +A   L+L ++ RQ
Sbjct: 239 VQCPEVAPPTRPRTVCRVPGQIEVLR---------GFLEDVVPDATSAYPYLLLYES-RQ 288

Query: 351 VRFVGAKVSGPSCLEKH----YDCSVLGSQHFSSGKHYWEV--DVAKKTAWILGVCSNSL 404
            R++G+   G     K     Y C+V G   FSSG+HYWEV  ++     W LGVC +  
Sbjct: 289 RRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSSGRHYWEVGMNITGDALWALGVCRD-- 345

Query: 405 GPTFSFNHFAQNHSAYSRYQ--PQSGYWVIGLQHNHEY-RAYEDSSPSLLLSMTVPPRRV 461
                      N S   R    P++G+WV+ L    +Y   +   +P +L+    PP  +
Sbjct: 346 -----------NVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLME---PPSHM 391

Query: 462 GVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500
           G+FLD+EAG VSFY+V++ G  ++T+S+  FP  L P+F
Sbjct: 392 GIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPFF 429


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  206 bits (524), Expect = 4e-53
 Identities = 152/500 (30%), Positives = 238/500 (47%), Gaps = 50/500 (10%)

Query: 36  DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS--------CPVC 87
           +++ E TC ICLEL  EP+S++CGHSFC+ACI         G  G  +        CP C
Sbjct: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81

Query: 88  QTSYQPGNLRPNRHLANIVRRLREVVL---GPGK--------QLKAVLCADHGEKLQLFC 136
           +   +P  LRPNR LA +   LR   L    PG+        +  A  C  HGE  +L+C
Sbjct: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141

Query: 137 QEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREK 196
           Q+DG+ IC +C+R++EHR H    ++E  QE +E  +  L+ LK E ++ E   +  +++
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 197 KTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQ 256
                 QM  E+ ++  EF  LR  L   E R L +LE+  ++  +   E    L  +  
Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261

Query: 257 SLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS-----MFRAPDL 311
            L +L S ++   Q   ++ LQ+      R       KP  + +++++       +   L
Sbjct: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321

Query: 312 KRMLRVCRELTDVQSYW-----VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK 366
           K ML+  +E  D++        V++TL+P TAN  L+L+ + + VR +G +         
Sbjct: 322 KGMLKKFKE--DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVR-LGERAQDLPNHPC 378

Query: 367 HYDCS--VLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ 424
            +D +  VL S  FSSG+H+WEV+V  K  W  GV   S+                + + 
Sbjct: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV-----------RRKGLTPFT 427

Query: 425 PQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPI 484
           P+ G W + L +  +Y A      S L    +   RV V LD E G VSFY V +    +
Sbjct: 428 PEEGVWALQL-NGGQYWAVTSPERSPLSCGHL--SRVRVALDLEVGAVSFYAVEDMRH-L 483

Query: 485 YTFSKYYFPTTLCPYFNPCN 504
           YTF +  F   + P F+ C+
Sbjct: 484 YTF-RVNFQERVFPLFSVCS 502


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  201 bits (510), Expect = 2e-51
 Identities = 148/501 (29%), Positives = 235/501 (46%), Gaps = 81/501 (16%)

Query: 36  DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
           DI+EE+TCPICL+   +P+SI+CGH+FC+ C+  N         G   CP C+    P  
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60

Query: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
           LRPN  LA +  + +   LGP   +   LC  H E L+LFC++D + +C +C  SQEH+ 
Sbjct: 61  LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 156 HHTFLVEEVAQEY--------------------------QEKFQESLKKLKNEEQEAEKL 189
           H    ++E  + Y                          +EK  +S + L  + ++   L
Sbjct: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177

Query: 190 TAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 249
                +  T WK++++ +R RI TEF++L N L   E   L++L +EE++  + + E   
Sbjct: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237

Query: 250 DLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRA 308
            L     SL++LI ++  + Q  T+ELLQ+  +V  RSE   +    EA+  K++++ + 
Sbjct: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQI 295

Query: 309 PDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP------- 361
           P +K ML+          + V V L   TA+  LV ++  R V+   +  S P       
Sbjct: 296 PLMKEMLK---------RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346

Query: 362 -----------SCLEK--HYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTF 408
                      + +E+  H  C VLG   F+SGKHYWEV+        +GVC   +    
Sbjct: 347 YFAGWRNPQKTAFVERFQHLPC-VLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGIT 405

Query: 409 SFNHFAQNHSAYSRYQPQSGYW-VIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDY 467
             +  + +   ++ Y   +GYW +IG              P           RVGV+LD 
Sbjct: 406 DRSKMSPDVGIWAIYWSAAGYWPLIGF-------------PGTPTQQEPALHRVGVYLDR 452

Query: 468 EAGTVSFYNVTNHGFPIYTFS 488
             G VSFY+  + G  ++TFS
Sbjct: 453 GTGNVSFYSAVD-GVHLHTFS 472


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  199 bits (505), Expect = 7e-51
 Identities = 149/483 (30%), Positives = 223/483 (46%), Gaps = 61/483 (12%)

Query: 44  PICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ---PGNLRPNR 100
           P C     +P+   C    C      +G     G      CP CQ S++   PG+L P +
Sbjct: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSP-GCPRCQDSHERKSPGSLSP-Q 370

Query: 101 HLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFL 160
            L    R L++V L                   LFC++  + IC +C  SQEH+GH    
Sbjct: 371 PLPQCKRHLKQVQL-------------------LFCEDHDEPICLICSLSQEHQGHRVRP 411

Query: 161 VEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRN 220
           +EEVA E+++K Q+ L+ LK   +  E+  ++  EK  S+  Q E  + R+Q +  Q+  
Sbjct: 412 IEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471

Query: 221 ILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDV 280
            L++ E   +  LE   +   +I +  +  +      L  LI +LE +   S  ELLQD+
Sbjct: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531

Query: 281 SDVTERS------EFWTLRKPEALPTKL-----RSMFRAPDLKRMLRVCR---------E 320
            D+  R+      E WT   P+ +  K+     +S F     K      R         E
Sbjct: 532 GDILHRAKTVPVPEKWT--TPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPE 589

Query: 321 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFS 379
           L   Q++ V+V L+  TA  NL+ + + + VR        P   ++   C  VLGS  F 
Sbjct: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649

Query: 380 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 439
           SG+ YWEV+V  KTAWILG C  S+           +        P++GYWV+ +   +E
Sbjct: 650 SGRRYWEVEVGDKTAWILGACKTSI-----------SRKGNMTLSPENGYWVVIMMKENE 698

Query: 440 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 499
           Y+A   S P   L +  PP+RVG+F+DY  G++SFYNVT     IYTF+   F   L P 
Sbjct: 699 YQA--SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSH-IYTFASCSFSGPLQPI 755

Query: 500 FNP 502
           F+P
Sbjct: 756 FSP 758


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  198 bits (504), Expect = 9e-51
 Identities = 136/444 (30%), Positives = 217/444 (48%), Gaps = 34/444 (7%)

Query: 83  SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 139
           +CP C+ S+   + RPN  LAN+V+ +R++   PG+  +     +C  H E L+LFC+ D
Sbjct: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241

Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199
            + IC +C  S+ H+ H    +EEV QEY+ K Q  ++ L+   +  +K+ A    + T 
Sbjct: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301

Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259
            K+QM+ E   + +EF +L   L   +    ++L +  +  L     A + L  Q   L 
Sbjct: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361

Query: 260 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 314
            L+++ + R Q   + LLQD+ +   R E   L+ PE     P +  S     D  +++M
Sbjct: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421

Query: 315 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 373
            R+       Q+  VD+TL+P TA+  L+L+ +RR VR    +       ++   DC VL
Sbjct: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476

Query: 374 GSQHFSSGKHYWEVDVAKKTAWILGVCSNSL---------------GPTFSFNHFAQNHS 418
           G+Q F SG+HYWEV+V  +  W +G    S                G   S  H  +   
Sbjct: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536

Query: 419 AYSRYQP--QSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYN 476
            +   QP  Q   W +G  +   Y+A + S+   LLS +  PRR GV+LDYEAG + FYN
Sbjct: 537 LHLPQQPLLQREVWCVG-TNGKRYQA-QSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594

Query: 477 VTNHGFPIYTFSKYYFPTTLCPYF 500
                  ++TFS  +    + P+F
Sbjct: 595 AETLAH-VHTFSAAFLGERVFPFF 617



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 19/40 (47%), Positives = 28/40 (70%)

Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 68
          MT   +  ++EE  C ICL+  T+P+SI CGH+FC+ C+T
Sbjct: 6  MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,319,173
Number of Sequences: 37866
Number of extensions: 1004720
Number of successful extensions: 6629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 303
Number of HSP's successfully gapped in prelim test: 599
Number of HSP's that attempted gapping in prelim test: 4248
Number of HSP's gapped (non-prelim): 2083
length of query: 516
length of database: 18,247,518
effective HSP length: 107
effective length of query: 409
effective length of database: 14,195,856
effective search space: 5806105104
effective search space used: 5806105104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.