Guide to the Human Genome
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Search of human proteins with 48762732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
         (507 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]            1035   0.0  
gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]            1021   0.0  
gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]             960   0.0  
gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]             943   0.0  
gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]             941   0.0  
gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]             920   0.0  
gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]             914   0.0  
gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]             914   0.0  
gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]              914   0.0  
gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]             909   0.0  
gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]             905   0.0  
gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]             885   0.0  
gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]             882   0.0  
gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]            177   2e-44
gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]             177   2e-44
gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]             177   2e-44
gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]             177   2e-44
gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]            177   3e-44
gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]            177   3e-44
gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]            177   3e-44
gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]              177   3e-44

>gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
          Length = 507

 Score = 1035 bits (2677), Expect = 0.0
 Identities = 507/507 (100%), Positives = 507/507 (100%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60

Query: 61  SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK 120
           SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
Sbjct: 61  SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK 120

Query: 121 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 180
           KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
Sbjct: 121 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 180

Query: 181 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 240
           EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
Sbjct: 181 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 240

Query: 241 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 300
           MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
Sbjct: 241 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 300

Query: 301 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 360
           AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
Sbjct: 301 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 360

Query: 361 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 420
           EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
Sbjct: 361 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 420

Query: 421 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 480
           VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
Sbjct: 421 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 480

Query: 481 TDSLTSGATEKSRERSRDVKNSEGDCA 507
           TDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 481 TDSLTSGATEKSRERSRDVKNSEGDCA 507


>gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
          Length = 533

 Score = 1021 bits (2640), Expect = 0.0
 Identities = 507/533 (95%), Positives = 507/533 (95%), Gaps = 26/533 (4%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR------------- 47
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR             
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 48  -------------TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 94
                        TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
Sbjct: 61  VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 120

Query: 95  LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 154
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 121 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180

Query: 155 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 214
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240

Query: 215 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 274
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300

Query: 275 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 334
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360

Query: 335 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 394
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420

Query: 395 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 454
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480

Query: 455 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533


>gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]
          Length = 540

 Score =  960 bits (2481), Expect = 0.0
 Identities = 484/541 (89%), Positives = 489/541 (90%), Gaps = 35/541 (6%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTP----------- 49
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR             
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 50  YKVRPVAIKQLSEREELI---------------------QSVLAQVA--EQFSRAFKINE 86
             + P  +   SER ELI                      SV ++    +   RAFKINE
Sbjct: 61  VSIDP-TMPANSERNELILYTSLRNLLFLPSKESWASHQHSVQSETCGHQATLRAFKINE 119

Query: 87  LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK 146
           LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
Sbjct: 120 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK 179

Query: 147 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP 206
           KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
Sbjct: 180 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP 239

Query: 207 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH 266
           VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
Sbjct: 240 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH 299

Query: 267 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI 326
           DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
Sbjct: 300 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI 359

Query: 327 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV 386
           RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
Sbjct: 360 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV 419

Query: 387 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF 446
           AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
Sbjct: 420 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF 479

Query: 447 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC 506
           PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
Sbjct: 480 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC 539

Query: 507 A 507
           A
Sbjct: 540 A 540


>gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]
          Length = 492

 Score =  943 bits (2437), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 47  RTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEG 106
           RTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEG
Sbjct: 32  RTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEG 91

Query: 107 LKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPET 166
           LKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPET
Sbjct: 92  LKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPET 151

Query: 167 IEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFH 226
           IEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFH
Sbjct: 152 IEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFH 211

Query: 227 NFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELA 286
           NFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELA
Sbjct: 212 NFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELA 271

Query: 287 VRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIM 346
           VRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIM
Sbjct: 272 VRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIM 331

Query: 347 DSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREK 406
           DSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREK
Sbjct: 332 DSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREK 391

Query: 407 SEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEE 466
           SEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEE
Sbjct: 392 SEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEE 451

Query: 467 LKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           LKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 452 LKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 492


>gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]
          Length = 466

 Score =  941 bits (2432), Expect = 0.0
 Identities = 460/460 (100%), Positives = 460/460 (100%)

Query: 48  TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 107
           TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL
Sbjct: 7   TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 66

Query: 108 KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 167
           KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI
Sbjct: 67  KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 126

Query: 168 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 227
           EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN
Sbjct: 127 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 186

Query: 228 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 287
           FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV
Sbjct: 187 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 246

Query: 288 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 347
           RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD
Sbjct: 247 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 306

Query: 348 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 407
           SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS
Sbjct: 307 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 366

Query: 408 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 467
           EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL
Sbjct: 367 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 426

Query: 468 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 427 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 466


>gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]
          Length = 567

 Score =  920 bits (2379), Expect = 0.0
 Identities = 472/567 (83%), Positives = 481/567 (84%), Gaps = 60/567 (10%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60

Query: 61  S---------------EREELIQSVLAQVAEQFSRAFK---------------------- 83
           S               ER    + V+     +   AF+                      
Sbjct: 61  SAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIP 120

Query: 84  ------INELKAEVANHLAVLEKRVELEG-----LKVVE------------IEKCKSDIK 120
                 I  + A+VA   +   K  EL+      L V+E            IEKCKSDIK
Sbjct: 121 PEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK 180

Query: 121 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 180
           KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
Sbjct: 181 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 240

Query: 181 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 240
           EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
Sbjct: 241 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 300

Query: 241 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 300
           MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
Sbjct: 301 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 360

Query: 301 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 360
           AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
Sbjct: 361 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 420

Query: 361 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 420
           EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
Sbjct: 421 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 480

Query: 421 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 480
           VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
Sbjct: 481 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 540

Query: 481 TDSLTSGATEKSRERSRDVKNSEGDCA 507
           TDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 541 TDSLTSGATEKSRERSRDVKNSEGDCA 567


>gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]
          Length = 552

 Score =  914 bits (2363), Expect = 0.0
 Identities = 449/462 (97%), Positives = 450/462 (97%)

Query: 46  PRTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 105
           PR P        +   EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE
Sbjct: 91  PREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 150

Query: 106 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 165
           GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE
Sbjct: 151 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 210

Query: 166 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 225
           TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF
Sbjct: 211 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 270

Query: 226 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 285
           HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL
Sbjct: 271 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 330

Query: 286 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 345
           AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI
Sbjct: 331 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 390

Query: 346 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 405
           MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE
Sbjct: 391 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 450

Query: 406 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 465
           KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE
Sbjct: 451 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 510

Query: 466 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 511 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 552


>gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]
          Length = 526

 Score =  914 bits (2363), Expect = 0.0
 Identities = 449/462 (97%), Positives = 450/462 (97%)

Query: 46  PRTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 105
           PR P        +   EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE
Sbjct: 65  PREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 124

Query: 106 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 165
           GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE
Sbjct: 125 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 184

Query: 166 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 225
           TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF
Sbjct: 185 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 244

Query: 226 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 285
           HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL
Sbjct: 245 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 304

Query: 286 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 345
           AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI
Sbjct: 305 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 364

Query: 346 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 405
           MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE
Sbjct: 365 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 424

Query: 406 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 465
           KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE
Sbjct: 425 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 484

Query: 466 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 485 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 526


>gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]
          Length = 593

 Score =  914 bits (2363), Expect = 0.0
 Identities = 449/462 (97%), Positives = 450/462 (97%)

Query: 46  PRTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 105
           PR P        +   EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE
Sbjct: 132 PREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 191

Query: 106 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 165
           GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE
Sbjct: 192 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 251

Query: 166 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 225
           TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF
Sbjct: 252 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 311

Query: 226 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 285
           HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL
Sbjct: 312 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 371

Query: 286 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 345
           AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI
Sbjct: 372 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 431

Query: 346 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 405
           MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE
Sbjct: 432 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 491

Query: 406 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 465
           KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE
Sbjct: 492 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 551

Query: 466 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 552 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593


>gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]
          Length = 491

 Score =  909 bits (2350), Expect = 0.0
 Identities = 458/509 (89%), Positives = 464/509 (91%), Gaps = 20/509 (3%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60
           MGSGSSSYRPKAIYLDIDGRIQK                     LP   ++ R    +  
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKE-----------------HDHLP-ADHRRRHGLHRPH 42

Query: 61  SEREELIQSVLAQVA--EQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSD 118
             RE    SV ++    +   RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSD
Sbjct: 43  HAREFRTHSVQSETCGHQATLRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSD 102

Query: 119 IKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVW 178
           IKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVW
Sbjct: 103 IKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVW 162

Query: 179 LWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMM 238
           LWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMM
Sbjct: 163 LWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMM 222

Query: 239 YSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENH 298
           YSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENH
Sbjct: 223 YSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENH 282

Query: 299 HCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDY 358
           HCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDY
Sbjct: 283 HCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDY 342

Query: 359 SNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDR 418
           SNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDR
Sbjct: 343 SNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDR 402

Query: 419 DKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQ 478
           DKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQ
Sbjct: 403 DKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQ 462

Query: 479 KKTDSLTSGATEKSRERSRDVKNSEGDCA 507
           KKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 463 KKTDSLTSGATEKSRERSRDVKNSEGDCA 491


>gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]
          Length = 465

 Score =  905 bits (2339), Expect = 0.0
 Identities = 453/508 (89%), Positives = 456/508 (89%), Gaps = 44/508 (8%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQK-VIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQ 59
           MGSGSSSYRPKAIYLDIDGRIQK  + S+ C     +                       
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKHSVQSETCGHQATL----------------------- 37

Query: 60  LSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDI 119
                               RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDI
Sbjct: 38  --------------------RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDI 77

Query: 120 KKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWL 179
           KKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWL
Sbjct: 78  KKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWL 137

Query: 180 WEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMY 239
           WEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMY
Sbjct: 138 WEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMY 197

Query: 240 SMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHH 299
           SMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHH
Sbjct: 198 SMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHH 257

Query: 300 CAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS 359
           CAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS
Sbjct: 258 CAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYS 317

Query: 360 NEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRD 419
           NEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRD
Sbjct: 318 NEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRD 377

Query: 420 KVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQK 479
           KVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQK
Sbjct: 378 KVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQK 437

Query: 480 KTDSLTSGATEKSRERSRDVKNSEGDCA 507
           KTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 438 KTDSLTSGATEKSRERSRDVKNSEGDCA 465


>gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]
          Length = 433

 Score =  885 bits (2286), Expect = 0.0
 Identities = 429/432 (99%), Positives = 430/432 (99%)

Query: 76  EQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 135
           + F RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC
Sbjct: 2   DAFRRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 61

Query: 136 PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 195
           PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD
Sbjct: 62  PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 121

Query: 196 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 255
           LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD
Sbjct: 122 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 181

Query: 256 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 315
           ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF
Sbjct: 182 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 241

Query: 316 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 375
           SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC
Sbjct: 242 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 301

Query: 376 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 435
           DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL
Sbjct: 302 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 361

Query: 436 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 495
           IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER
Sbjct: 362 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 421

Query: 496 SRDVKNSEGDCA 507
           SRDVKNSEGDCA
Sbjct: 422 SRDVKNSEGDCA 433


>gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]
          Length = 459

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 80  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 139
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 32  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 91

Query: 140 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 199
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 92  SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 151

Query: 200 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 259
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 152 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 211

Query: 260 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 319
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 212 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 271

Query: 320 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 379
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 272 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 331

Query: 380 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 439
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 332 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 391

Query: 440 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 499
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 392 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 451

Query: 500 KNSEGDCA 507
           KNSEGDCA
Sbjct: 452 KNSEGDCA 459


>gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 122 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 181
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 182 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 241
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 242 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 301
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 302 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 361
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 362 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 421
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 422 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 481
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 482 DSLTSGATEKSRERSRDVKNSEGDCA 507
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 122 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 181
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 182 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 241
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 242 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 301
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 302 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 361
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 362 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 421
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 422 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 481
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 482 DSLTSGATEKSRERSRDVKNSEGDCA 507
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 122 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 181
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 182 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 241
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 242 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 301
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 302 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 361
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 362 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 421
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 422 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 481
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 482 DSLTSGATEKSRERSRDVKNSEGDCA 507
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 122 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 181
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 182 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 241
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 242 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 301
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 302 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 361
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 362 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 421
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 422 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 481
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 482 DSLTSGATEKSRERSRDVKNSEGDCA 507
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 122 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 181
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 182 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 241
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 242 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 301
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 302 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 361
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 362 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 421
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 422 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 481
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 482 DSLTSGATEKSRERSRDVKNSEGDCA 507
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 133 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 192
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 193 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 252
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 253 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 312
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 313 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 372
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 373 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 432
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 433 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 492
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 493 RERSRDVKNSEGDCA 507
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 133 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 192
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 193 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 252
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 253 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 312
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 313 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 372
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 373 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 432
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 433 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 492
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 493 RERSRDVKNSEGDCA 507
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 158 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 206
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 382 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 441

Query: 207 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 265
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 442 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 501

Query: 266 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 325
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 502 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 561

Query: 326 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 377
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 562 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 621

Query: 378 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 437
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 622 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 681

Query: 438 MFETVTKLFPMVEEIMLQPLWESRDRYE 465
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 682 LWETWADLVHPDAQDILDTLEDNREWYQ 709


>gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]
          Length = 673

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 158 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 206
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 246 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 305

Query: 207 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 265
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 306 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 365

Query: 266 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 325
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 366 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 425

Query: 326 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 377
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 426 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 485

Query: 378 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 437
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 486 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 545

Query: 438 MFETVTKLFPMVEEIMLQPLWESRDRYE 465
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 546 LWETWADLVHPDAQDILDTLEDNREWYQ 573


>gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 175 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 232
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 233 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 292
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 293 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 352
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 353 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 404
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 405 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 464
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 465 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 504
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]
          Length = 721

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 175 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 232
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 338 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 397

Query: 233 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 292
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 398 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 457

Query: 293 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 352
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 458 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 517

Query: 353 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 404
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 518 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 577

Query: 405 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 464
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 578 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 637

Query: 465 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 504
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 638 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 676


>gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]
          Length = 564

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 175 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 232
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 181 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 240

Query: 233 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 292
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 241 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 300

Query: 293 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 352
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 301 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 360

Query: 353 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 404
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 361 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 420

Query: 405 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 464
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 421 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 480

Query: 465 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 504
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 481 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 519


>gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 175 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 232
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 233 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 292
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 293 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 352
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 353 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 404
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 405 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 464
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 465 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 504
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]
          Length = 825

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 150 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 205
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 292 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 350

Query: 206 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 264
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 351 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 410

Query: 265 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 324
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 411 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 470

Query: 325 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 376
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 471 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 530

Query: 377 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 436
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 531 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 590

Query: 437 PMFETVTKLFPMVEEIMLQPLWESRDRY 464
           P++ET   L     + +L  L ++RD Y
Sbjct: 591 PLWETWADLVHPDAQEILDTLEDNRDWY 618


>gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]
          Length = 860

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 150 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 205
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 327 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 385

Query: 206 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 264
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 386 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 445

Query: 265 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 324
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 446 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 505

Query: 325 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 376
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 506 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 565

Query: 377 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 436
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 566 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 625

Query: 437 PMFETVTKLFPMVEEIMLQPLWESRDRY 464
           P++ET   L     + +L  L ++RD Y
Sbjct: 626 PLWETWADLVHPDAQEILDTLEDNRDWY 653


>gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]
          Length = 886

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 150 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 205
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 353 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 411

Query: 206 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 264
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 412 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 471

Query: 265 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 324
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 472 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 531

Query: 325 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 376
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 532 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 591

Query: 377 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 436
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 592 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 651

Query: 437 PMFETVTKLFPMVEEIMLQPLWESRDRY 464
           P++ET   L     + +L  L ++RD Y
Sbjct: 652 PLWETWADLVHPDAQEILDTLEDNRDWY 679


>gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]
          Length = 647

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 150 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 205
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 114 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 172

Query: 206 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 264
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 173 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 232

Query: 265 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 324
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 233 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 292

Query: 325 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 376
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 293 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 352

Query: 377 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 436
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 353 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 412

Query: 437 PMFETVTKLFPMVEEIMLQPLWESRDRY 464
           P++ET   L     + +L  L ++RD Y
Sbjct: 413 PLWETWADLVHPDAQEILDTLEDNRDWY 440


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,479,056
Number of Sequences: 37866
Number of extensions: 783065
Number of successful extensions: 2710
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2493
Number of HSP's gapped (non-prelim): 154
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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