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Search of human proteins with 125987593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125987593 leukocyte immunoglobulin-like receptor, subfamily
B, member 5 isoform 3 [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 1005 0.0
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 800 0.0
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 794 0.0
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 590 e-168
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 583 e-167
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 540 e-153
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 540 e-153
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 535 e-152
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 534 e-152
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 532 e-151
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 532 e-151
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 365 e-101
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B... 351 1e-96
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B... 350 1e-96
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 340 1e-93
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A... 331 1e-90
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (... 323 3e-88
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 315 6e-86
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 313 3e-85
gi|134268642 killer cell immunoglobulin-like receptor, three dom... 232 7e-61
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 228 1e-59
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m... 225 8e-59
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m... 224 2e-58
gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like... 218 1e-56
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 211 9e-55
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 211 2e-54
gi|32895365 leukocyte immunoglobulin-like receptor subfamily A m... 197 1e-50
gi|32895363 leukocyte immunoglobulin-like receptor subfamily A m... 196 3e-50
gi|71143139 killer cell immunoglobulin-like receptor, two domain... 186 4e-47
gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 185 7e-47
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 1005 bits (2598), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF
Sbjct: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
Query: 181 TLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENV 240
TLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENV
Sbjct: 181 TLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENV 240
Query: 241 TLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIR 300
TLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIR
Sbjct: 241 TLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIR 300
Query: 301 SYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGV 360
SYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGV
Sbjct: 301 SYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGV 360
Query: 361 VTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADI 420
VTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADI
Sbjct: 361 VTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADI 420
Query: 421 QEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPA 480
QEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPA
Sbjct: 421 QEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPA 480
Query: 481 EPSIYAPLAIH 491
EPSIYAPLAIH
Sbjct: 481 EPSIYAPLAIH 491
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 800 bits (2066), Expect = 0.0
Identities = 408/480 (85%), Positives = 422/480 (87%), Gaps = 5/480 (1%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQ--GPLETEEYRLDKEGLPWARKRQNP 74
P V G +PTL A P+ V+A G VTL C L T +++ LP Q
Sbjct: 112 PLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKL 171
Query: 75 LEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQG 131
+ ++A F + R+RCYY + P WS PSD LE++ GVSRKPSLLIPQG
Sbjct: 172 PKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQG 231
Query: 132 SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG 191
SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG
Sbjct: 232 SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG 291
Query: 192 QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID 251
QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID
Sbjct: 292 QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID 351
Query: 252 TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY 311
TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY
Sbjct: 352 TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY 411
Query: 312 PQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL 371
PQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL
Sbjct: 412 PQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL 471
Query: 372 LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD 431
LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD
Sbjct: 472 LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD 531
Query: 432 TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 491
TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH
Sbjct: 532 TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 591
Score = 358 bits (919), Expect = 6e-99
Identities = 198/329 (60%), Positives = 234/329 (71%), Gaps = 4/329 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATG
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
+P+LL VVA GG++TLQC + G FVL +E + Q+ G SQA F
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALF 180
Query: 181 TLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASGEN 239
+GPV+ S ++RCY + +P+ WS PSD L+IL+ G + P+L + G VA G +
Sbjct: 181 PVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG-VSRKPSLLIPQGSVVARGGS 239
Query: 240 VTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAI 299
+TL C+S D F L KEG + Q+ QA F++ PV+ + GG YRCY A
Sbjct: 240 LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 299
Query: 300 RSYPYLLSSPSYPQELVVSGPSGD-PSLS 327
P S+PS P +++++G D P+LS
Sbjct: 300 NLSP-RWSAPSDPLDILIAGLIPDIPALS 327
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 211 PLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSK 270
P + AG +P P L +P +A G+ VTL CQ + + + L KEG P +
Sbjct: 17 PRTCVQAGTLPK-PTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL--PWARKRQN 73
Query: 271 YQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTG 330
+A+F + G YRCY P S PS P ELV +G +P+L
Sbjct: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALP 130
Query: 331 STPTPAG 337
S +G
Sbjct: 131 SPVVASG 137
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 794 bits (2050), Expect = 0.0
Identities = 407/480 (84%), Positives = 421/480 (87%), Gaps = 6/480 (1%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQ--GPLETEEYRLDKEGLPWARKRQNP 74
P V G +PTL A P+ V+A G VTL C L T +++ LP Q
Sbjct: 112 PLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKL 171
Query: 75 LEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQG 131
+ ++A F + R+RCYY + P WS PSD LE++ GVSRKPSLLIPQG
Sbjct: 172 PKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQG 231
Query: 132 SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG 191
SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG
Sbjct: 232 SVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGG 291
Query: 192 QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID 251
QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID
Sbjct: 292 QYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQID 351
Query: 252 TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY 311
TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY
Sbjct: 352 TFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY 411
Query: 312 PQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL 371
PQELVVSGPSGDPSLSPTGSTPTP GPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL
Sbjct: 412 PQELVVSGPSGDPSLSPTGSTPTP-GPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLL 470
Query: 372 LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD 431
LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD
Sbjct: 471 LFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKD 530
Query: 432 TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 491
TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH
Sbjct: 531 TQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 590
Score = 358 bits (919), Expect = 6e-99
Identities = 198/329 (60%), Positives = 234/329 (71%), Gaps = 4/329 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATG
Sbjct: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
+P+LL VVA GG++TLQC + G FVL +E + Q+ G SQA F
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALF 180
Query: 181 TLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASGEN 239
+GPV+ S ++RCY + +P+ WS PSD L+IL+ G + P+L + G VA G +
Sbjct: 181 PVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG-VSRKPSLLIPQGSVVARGGS 239
Query: 240 VTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAI 299
+TL C+S D F L KEG + Q+ QA F++ PV+ + GG YRCY A
Sbjct: 240 LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 299
Query: 300 RSYPYLLSSPSYPQELVVSGPSGD-PSLS 327
P S+PS P +++++G D P+LS
Sbjct: 300 NLSP-RWSAPSDPLDILIAGLIPDIPALS 327
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 211 PLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSK 270
P + AG +P P L +P +A G+ VTL CQ + + + L KEG P +
Sbjct: 17 PRTCVQAGTLPK-PTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL--PWARKRQN 73
Query: 271 YQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTG 330
+A+F + G YRCY P S PS P ELV +G +P+L
Sbjct: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALP 130
Query: 331 STPTPAG 337
S +G
Sbjct: 131 SPVVASG 137
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 590 bits (1520), Expect = e-168
Identities = 321/487 (65%), Positives = 352/487 (72%), Gaps = 12/487 (2%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARKRQN 73
P V G PKPTL A+P+ V+ G VTL C+ + + L KEG P Q
Sbjct: 112 PLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQP 171
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
++A F + + +RCY +P WS PSD LEL+ GVS+KPSL +
Sbjct: 172 HARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQP 231
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G VVA G SLTLQC SDVGYD FVLYKEGE DL Q G+QPQAGLSQANFTLGPVSRS+G
Sbjct: 232 GPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCYGAHNLS SAPSDPLDILI G I P +SVQPGP VASGENVTLLCQSW Q
Sbjct: 292 GQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQF 351
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
TF LTK GAA PL L+S ++ ++QAEF MSPVTSA GTYRCY ++ S PYLLS PS
Sbjct: 352 HTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPS 411
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFV- 369
P ELVVSGPS S PTG TPAGPEDQPLTPTG DPQSGLGRHLGVV G+ VA V
Sbjct: 412 EPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVL 471
Query: 370 -LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQEEI 424
LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD QEE
Sbjct: 472 LLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEEN 531
Query: 425 LNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSI 484
L AAVKDTQP+DGVEMD RAAASEAPQDVTYAQLHSLTLRR+ATEPPPSQEREPPAEPSI
Sbjct: 532 LYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPPPSQEREPPAEPSI 591
Query: 485 YAPLAIH 491
YA LAIH
Sbjct: 592 YATLAIH 598
Score = 265 bits (678), Expect = 5e-71
Identities = 162/348 (46%), Positives = 209/348 (60%), Gaps = 10/348 (2%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT ++VLICLGLS+GPRT VQ GT+PKPTLWAEP SVI +G PVTL CQG LE +EYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 --DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVAT 118
+K+ W + + L +FHIPS ++ GRY C Y + A WSE SDPL LV T
Sbjct: 61 YREKKSASWITRIRPELV--KNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQ 177
G KP+L VV GG +TLQC S V + F+L KEGE + Q QP A G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 178 ANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
A F++GPVS + +RCYG SP WS+PSD L++L+ G + P+LSVQPGP VA
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG-VSKKPSLSVQPGPVVAP 237
Query: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
GE++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRCY
Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 297 SAIRSYPYLLSSPSYPQELVVSGP-SGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G G P +S PT A E+ L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFIS-VQPGPTVASGENVTL 343
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 583 bits (1504), Expect = e-167
Identities = 320/487 (65%), Positives = 351/487 (72%), Gaps = 13/487 (2%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARKRQN 73
P V G PKPTL A+P+ V+ G VTL C+ + + L KEG P Q
Sbjct: 112 PLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQP 171
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
++A F + + +RCY +P WS PSD LEL+ GVS+KPSL +
Sbjct: 172 HARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQP 231
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G VVA G SLTLQC SDVGYD FVLYKEGE DL Q G+QPQAGLSQANFTLGPVSRS+G
Sbjct: 232 GPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCYGAHNLS SAPSDPLDILI G I P +SVQPGP VASGENVTLLCQSW Q
Sbjct: 292 GQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQF 351
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
TF LTK GAA PL L+S ++ ++QAEF MSPVTSA GTYRCY ++ S PYLLS PS
Sbjct: 352 HTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPS 411
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFV- 369
P ELVVSGPS S PTG TP GPEDQPLTPTG DPQSGLGRHLGVV G+ VA V
Sbjct: 412 EPLELVVSGPSMGSSPPPTGPISTP-GPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVL 470
Query: 370 -LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQEEI 424
LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD QEE
Sbjct: 471 LLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEEN 530
Query: 425 LNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSI 484
L AAVKDTQP+DGVEMD RAAASEAPQDVTYAQLHSLTLRR+ATEPPPSQEREPPAEPSI
Sbjct: 531 LYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPPPSQEREPPAEPSI 590
Query: 485 YAPLAIH 491
YA LAIH
Sbjct: 591 YATLAIH 597
Score = 265 bits (678), Expect = 5e-71
Identities = 162/348 (46%), Positives = 209/348 (60%), Gaps = 10/348 (2%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT ++VLICLGLS+GPRT VQ GT+PKPTLWAEP SVI +G PVTL CQG LE +EYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 --DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVAT 118
+K+ W + + L +FHIPS ++ GRY C Y + A WSE SDPL LV T
Sbjct: 61 YREKKSASWITRIRPELV--KNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQ 177
G KP+L VV GG +TLQC S V + F+L KEGE + Q QP A G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 178 ANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
A F++GPVS + +RCYG SP WS+PSD L++L+ G + P+LSVQPGP VA
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG-VSKKPSLSVQPGPVVAP 237
Query: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
GE++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRCY
Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 297 SAIRSYPYLLSSPSYPQELVVSGP-SGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G G P +S PT A E+ L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFIS-VQPGPTVASGENVTL 343
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 540 bits (1391), Expect = e-153
Identities = 311/542 (57%), Positives = 344/542 (63%), Gaps = 64/542 (11%)
Query: 14 SVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARK 70
S P V G KPTL A+P+ V+ G V L C + + + L KEG P
Sbjct: 110 SSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLN 169
Query: 71 RQNPLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLL 127
Q ++A F + YRCY +P WS PSD LEL+ GVS+KPSL
Sbjct: 170 SQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Query: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187
+ G +VA +LTLQC SD GY+ FVLYK+GE D +Q +G QPQAGLSQANFTLGPVSR
Sbjct: 230 VQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSR 289
Query: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247
S+GGQYRCYGAHNLS WSAPSDPLDILIAG D +LSVQPGP VASGENVTLLCQS
Sbjct: 290 SYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQ 349
Query: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307
+ TF LTKEGAA P L+S YQS ++QAEF M PVTSA GTYRCY + S PYLL+
Sbjct: 350 GWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLT 409
Query: 308 SPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVA 367
PS P ELVVSGPSG PS TG T T AGPEDQPLTPTG DPQSGLGRHLGVV G+ VA
Sbjct: 410 HPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVA 469
Query: 368 FV--LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQ 421
+ LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD Q
Sbjct: 470 VILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQ 529
Query: 422 EEILNAAVKDTQPKDGVEMDAR-------------------------------------- 443
EE L AAVK TQP+DGVEMD R
Sbjct: 530 EENLYAAVKHTQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDT 589
Query: 444 --------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLA 489
AAASEAPQDVTYAQLHSLTLRREATEPPPSQE PA PSIYA LA
Sbjct: 590 KDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEPPPSQEGPSPAVPSIYATLA 649
Query: 490 IH 491
IH
Sbjct: 650 IH 651
Score = 262 bits (670), Expect = 5e-70
Identities = 164/346 (47%), Positives = 205/346 (59%), Gaps = 5/346 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG ET+EYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYY-ETPAGWSEPSDPLELVATG 119
+E + P E K +F IPS ++ AGRYRCYY AG SE SDPLELV TG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
KP+L VV GG++ LQC S V +D F L KEGE + Q QP A G S+A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG-VSKKPSLSVQPGPIVAPE 239
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E +TL C S + F L K+G ++ Q+ QA F++ PV+ + GG YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G D PT A E+ L
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 540 bits (1390), Expect = e-153
Identities = 311/543 (57%), Positives = 344/543 (63%), Gaps = 65/543 (11%)
Query: 14 SVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARK 70
S P V G KPTL A+P+ V+ G V L C + + + L KEG P
Sbjct: 110 SSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLN 169
Query: 71 RQNPLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLL 127
Q ++A F + YRCY +P WS PSD LEL+ GVS+KPSL
Sbjct: 170 SQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Query: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187
+ G +VA +LTLQC SD GY+ FVLYK+GE D +Q +G QPQAGLSQANFTLGPVSR
Sbjct: 230 VQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSR 289
Query: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247
S+GGQYRCYGAHNLS WSAPSDPLDILIAG D +LSVQPGP VASGENVTLLCQS
Sbjct: 290 SYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQ 349
Query: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307
+ TF LTKEGAA P L+S YQS ++QAEF M PVTSA GTYRCY + S PYLL+
Sbjct: 350 GWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLT 409
Query: 308 SPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVA 367
PS P ELVVSGPSG PS TG T T AGPEDQPLTPTG DPQSGLGRHLGVV G+ VA
Sbjct: 410 HPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVA 469
Query: 368 FV--LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQ 421
+ LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD Q
Sbjct: 470 VILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQ 529
Query: 422 EEILNAAVKDTQPKDGVEMDAR-------------------------------------- 443
EE L AAVK TQP+DGVEMD R
Sbjct: 530 EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLD 589
Query: 444 ---------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPL 488
AAASEAPQDVTYAQLHSLTLRREATEPPPSQE PA PSIYA L
Sbjct: 590 TKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEPPPSQEGPSPAVPSIYATL 649
Query: 489 AIH 491
AIH
Sbjct: 650 AIH 652
Score = 262 bits (670), Expect = 5e-70
Identities = 164/346 (47%), Positives = 205/346 (59%), Gaps = 5/346 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG ET+EYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYY-ETPAGWSEPSDPLELVATG 119
+E + P E K +F IPS ++ AGRYRCYY AG SE SDPLELV TG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
KP+L VV GG++ LQC S V +D F L KEGE + Q QP A G S+A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG-VSKKPSLSVQPGPIVAPE 239
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E +TL C S + F L K+G ++ Q+ QA F++ PV+ + GG YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G D PT A E+ L
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 535 bits (1377), Expect = e-152
Identities = 310/542 (57%), Positives = 344/542 (63%), Gaps = 65/542 (11%)
Query: 14 SVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARK 70
S P V G KPTL A+P+ V+ G V L C + + + L KEG P
Sbjct: 110 SSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLN 169
Query: 71 RQNPLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLL 127
Q ++A F + YRCY +P WS PSD LEL+ GVS+KPSL
Sbjct: 170 SQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Query: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187
+ G +VA +LTLQC SD GY+ FVLYK+GE D +Q +G QPQAGLSQANFTLGPVSR
Sbjct: 230 VQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSR 289
Query: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247
S+GGQYRCYGAHNLS WSAPSDPLDILIAG D +LSVQPGP VASGENVTLLCQS
Sbjct: 290 SYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQ 349
Query: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307
+ TF LTKEGAA P L+S YQS ++QAEF M PVTSA GTYRCY + S PYLL+
Sbjct: 350 GWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLT 409
Query: 308 SPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVA 367
PS P ELVVSGPSG PS TG T T +GPEDQPLTPTG DPQSGLGRHLGVV G+ VA
Sbjct: 410 HPSDPLELVVSGPSGGPSSPTTGPTST-SGPEDQPLTPTGSDPQSGLGRHLGVVIGILVA 468
Query: 368 FV--LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQ 421
+ LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD Q
Sbjct: 469 VILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQ 528
Query: 422 EEILNAAVKDTQPKDGVEMDAR-------------------------------------- 443
EE L AAVK TQP+DGVEMD R
Sbjct: 529 EENLYAAVKHTQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDT 588
Query: 444 --------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLA 489
AAASEAPQDVTYAQLHSLTLRREATEPPPSQE PA PSIYA LA
Sbjct: 589 KDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEPPPSQEGPSPAVPSIYATLA 648
Query: 490 IH 491
IH
Sbjct: 649 IH 650
Score = 262 bits (670), Expect = 5e-70
Identities = 164/346 (47%), Positives = 205/346 (59%), Gaps = 5/346 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG ET+EYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYY-ETPAGWSEPSDPLELVATG 119
+E + P E K +F IPS ++ AGRYRCYY AG SE SDPLELV TG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
KP+L VV GG++ LQC S V +D F L KEGE + Q QP A G S+A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG-VSKKPSLSVQPGPIVAPE 239
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E +TL C S + F L K+G ++ Q+ QA F++ PV+ + GG YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G D PT A E+ L
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 534 bits (1376), Expect = e-152
Identities = 310/543 (57%), Positives = 344/543 (63%), Gaps = 66/543 (12%)
Query: 14 SVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARK 70
S P V G KPTL A+P+ V+ G V L C + + + L KEG P
Sbjct: 110 SSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLN 169
Query: 71 RQNPLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLL 127
Q ++A F + YRCY +P WS PSD LEL+ GVS+KPSL
Sbjct: 170 SQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Query: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187
+ G +VA +LTLQC SD GY+ FVLYK+GE D +Q +G QPQAGLSQANFTLGPVSR
Sbjct: 230 VQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSR 289
Query: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247
S+GGQYRCYGAHNLS WSAPSDPLDILIAG D +LSVQPGP VASGENVTLLCQS
Sbjct: 290 SYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQ 349
Query: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307
+ TF LTKEGAA P L+S YQS ++QAEF M PVTSA GTYRCY + S PYLL+
Sbjct: 350 GWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLT 409
Query: 308 SPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVA 367
PS P ELVVSGPSG PS TG T T +GPEDQPLTPTG DPQSGLGRHLGVV G+ VA
Sbjct: 410 HPSDPLELVVSGPSGGPSSPTTGPTST-SGPEDQPLTPTGSDPQSGLGRHLGVVIGILVA 468
Query: 368 FV--LLLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQ 421
+ LLL LLLFL+LRHR Q KH TS A F PAGA GPEP D+GLQ R+SP AD Q
Sbjct: 469 VILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQ 528
Query: 422 EEILNAAVKDTQPKDGVEMDAR-------------------------------------- 443
EE L AAVK TQP+DGVEMD R
Sbjct: 529 EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLD 588
Query: 444 ---------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPL 488
AAASEAPQDVTYAQLHSLTLRREATEPPPSQE PA PSIYA L
Sbjct: 589 TKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEPPPSQEGPSPAVPSIYATL 648
Query: 489 AIH 491
AIH
Sbjct: 649 AIH 651
Score = 262 bits (670), Expect = 5e-70
Identities = 164/346 (47%), Positives = 205/346 (59%), Gaps = 5/346 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG ET+EYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYY-ETPAGWSEPSDPLELVATG 119
+E + P E K +F IPS ++ AGRYRCYY AG SE SDPLELV TG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
KP+L VV GG++ LQC S V +D F L KEGE + Q QP A G S+A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG-VSKKPSLSVQPGPIVAPE 239
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E +TL C S + F L K+G ++ Q+ QA F++ PV+ + GG YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
A + S+PS P +++++G D PT A E+ L
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 532 bits (1371), Expect = e-151
Identities = 308/537 (57%), Positives = 341/537 (63%), Gaps = 79/537 (14%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQN 73
P V G KPTL A P+ V+A G +TL C + L KEG LP Q
Sbjct: 112 PLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQ 171
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
G +A F + R+ CYY TP WS PSDPLE++ +GVSRKPSLL Q
Sbjct: 172 LHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQ 231
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G V+A G SLTLQC SDVGY+ FVLYKEGE D +Q GQQPQAGLSQANFTLGPVS S+G
Sbjct: 232 GPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNG 291
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCYGAHNLS WSAPSDPL+IL+AG I D +LS QPGP VASGENVTLLCQSW Q
Sbjct: 292 GQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQF 351
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
DTF LTKEGAAHPPL L+S Y ++++QAEF MSPVTSA GTYRCY + S P+LLS PS
Sbjct: 352 DTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPS 411
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVL 370
P ELVVSG SG SL PTG TP GLGR+L V+ GVSVAFVL
Sbjct: 412 EPLELVVSGHSGGSSLPPTGPPSTP-----------------GLGRYLEVLIGVSVAFVL 454
Query: 371 LLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILN 426
LLFLLLFLLLR + SKHRTS F RPAGAA EPKD+GL +R+SP AD+QEE L
Sbjct: 455 LLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLY 514
Query: 427 AAVKDTQPKDGVE----------------------------------------------- 439
AAVKDTQ +D VE
Sbjct: 515 AAVKDTQSEDRVELDSQSPHDEDPQAVTYAPVKHSSPRREMASPPSSLSGEFLDTKDRQV 574
Query: 440 -----MDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 491
MD AAASEA QDVTYAQLHSLTLRR+ATEPPPSQE EPPAEPSIYA LAIH
Sbjct: 575 EEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATLAIH 631
Score = 282 bits (722), Expect = 4e-76
Identities = 164/345 (47%), Positives = 208/345 (60%), Gaps = 4/345 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+ L+CLGLS+GPRT VQAG PKPTLWAEP SVI+ G PVT+WCQG E +EYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
KEG P R NPLEP KA+F IPS AGRYRC+Y + AGWSEPSDPLE+V TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQAN 179
KP+L VVA GG++TL+C S GY FVL KEGEH L + QQ + QA
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 180 FTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
F +GPV+ SH ++ CY + +P WS PSDPL+IL +G + P+L GP +A G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG-VSRKPSLLTLQGPVLAPGQ 239
Query: 239 NVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298
++TL C S + F L KEG + Q+ QA F++ PV+ + GG YRCY A
Sbjct: 240 SLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGA 299
Query: 299 IRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
+ S+PS P ++++G D PT A E+ L
Sbjct: 300 -HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 532 bits (1370), Expect = e-151
Identities = 308/538 (57%), Positives = 341/538 (63%), Gaps = 80/538 (14%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQN 73
P V G KPTL A P+ V+A G +TL C + L KEG LP Q
Sbjct: 112 PLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQ 171
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
G +A F + R+ CYY TP WS PSDPLE++ +GVSRKPSLL Q
Sbjct: 172 LHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQ 231
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G V+A G SLTLQC SDVGY+ FVLYKEGE D +Q GQQPQAGLSQANFTLGPVS S+G
Sbjct: 232 GPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNG 291
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCYGAHNLS WSAPSDPL+IL+AG I D +LS QPGP VASGENVTLLCQSW Q
Sbjct: 292 GQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQF 351
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
DTF LTKEGAAHPPL L+S Y ++++QAEF MSPVTSA GTYRCY + S P+LLS PS
Sbjct: 352 DTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPS 411
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVL 370
P ELVVSG SG SL PTG TP GLGR+L V+ GVSVAFVL
Sbjct: 412 EPLELVVSGHSGGSSLPPTGPPSTP-----------------GLGRYLEVLIGVSVAFVL 454
Query: 371 LLFLLLFLLLRHRHQSKHRTS----AHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILN 426
LLFLLLFLLLR + SKHRTS F RPAGAA EPKD+GL +R+SP AD+QEE L
Sbjct: 455 LLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLY 514
Query: 427 AAVKDTQPKDGVE----------------------------------------------- 439
AAVKDTQ +D VE
Sbjct: 515 AAVKDTQSEDRVELDSQQSPHDEDPQAVTYAPVKHSSPRREMASPPSSLSGEFLDTKDRQ 574
Query: 440 ------MDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH 491
MD AAASEA QDVTYAQLHSLTLRR+ATEPPPSQE EPPAEPSIYA LAIH
Sbjct: 575 VEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATLAIH 632
Score = 282 bits (722), Expect = 4e-76
Identities = 164/345 (47%), Positives = 208/345 (60%), Gaps = 4/345 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+ L+CLGLS+GPRT VQAG PKPTLWAEP SVI+ G PVT+WCQG E +EYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
KEG P R NPLEP KA+F IPS AGRYRC+Y + AGWSEPSDPLE+V TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQAN 179
KP+L VVA GG++TL+C S GY FVL KEGEH L + QQ + QA
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 180 FTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
F +GPV+ SH ++ CY + +P WS PSDPL+IL +G + P+L GP +A G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG-VSRKPSLLTLQGPVLAPGQ 239
Query: 239 NVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298
++TL C S + F L KEG + Q+ QA F++ PV+ + GG YRCY A
Sbjct: 240 SLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGA 299
Query: 299 IRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
+ S+PS P ++++G D PT A E+ L
Sbjct: 300 -HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 365 bits (936), Expect = e-101
Identities = 199/326 (61%), Positives = 222/326 (68%), Gaps = 6/326 (1%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQN 73
P V G KPTL A P+ V+A G +TL C + L KEG LP Q
Sbjct: 112 PLELVMTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQ 171
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
G +A F + R+ CYY TP WS PSDPLE++ +GVSRKPSLL Q
Sbjct: 172 LHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQ 231
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G V+A G SLTLQC SDVGYD FVLYKEGE D +Q GQQPQAGLSQANFTLGPVS SHG
Sbjct: 232 GPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHG 291
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCYGAHNLS WSAPSDPL+IL+AG I D +LS QPGP VASGENVTLLCQS
Sbjct: 292 GQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYF 351
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
DTF LTKEGAAHPPL L+S Y ++++QAEF MSPVTSA GTYRCY + S P+LLS PS
Sbjct: 352 DTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPS 411
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPA 336
P EL+VSG SG SL PTG TPA
Sbjct: 412 EPLELMVSGHSGGSSLPPTGPPSTPA 437
Score = 295 bits (755), Expect = 6e-80
Identities = 169/345 (48%), Positives = 212/345 (61%), Gaps = 4/345 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+ L+CLGLS+GPRT VQAG PKPTLWAEP SVI+ G PVT+WCQG LE +EY+L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKEG P R NPLEP KA+F IPS AGRYRC+Y + AGWSEPSDPLELV TG
Sbjct: 61 DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQAN 179
KP+L VVA GG++TL+C S GY FVL KEGEH L + QQ +G QA
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180
Query: 180 FTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
F +GPV+ SH ++ CY + +PR WS PSDPL+IL +G + P+L GP +A G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSG-VSRKPSLLTLQGPVLAPGQ 239
Query: 239 NVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298
++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRCY A
Sbjct: 240 SLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGA 299
Query: 299 IRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
+ S+PS P ++++G D PT A E+ L
Sbjct: 300 -HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 2 [Homo sapiens]
Length = 447
Score = 351 bits (900), Expect = 1e-96
Identities = 210/436 (48%), Positives = 254/436 (58%), Gaps = 61/436 (13%)
Query: 112 PLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQP 171
P + G KP+L GSV++ G S+T+ C+ + + L KE Q P
Sbjct: 17 PRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE--ESPAPWDRQNP 74
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPG 231
++A F++ ++ + G+YRCY + WS PSDPL++++ G P LS P
Sbjct: 75 LEPKNKARFSIPSMTEDYAGRYRCY--YRSPVGWSQPSDPLELVMTGAYSK-PTLSALPS 131
Query: 232 PKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGG 291
P V SG++VTLLCQS +DTF L KE AAHP L L+S++ + +HQAEF MSPVTS GG
Sbjct: 132 PLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGG 191
Query: 292 TYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQ 351
TYRC+S+ YLLS PS P EL+VSG DP SPT S T AGPEDQPL PTG P
Sbjct: 192 TYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPH 251
Query: 352 SGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRT----SAHFYRPAGAAGPEPKD 407
SGL RH V+ GV V +LLL LLLFLLL+H Q KHRT A F RP GAA PEPKD
Sbjct: 252 SGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADFQRPPGAAEPEPKD 311
Query: 408 QGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDAR------------------------ 443
GLQ+R+SP AD+Q E AAVK+TQP+DGVEMD R
Sbjct: 312 GGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRSPHDEDPQAVTYAKVKHSRPRREM 371
Query: 444 ----------------------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQE 475
AAASEAPQDVTYAQLHS TLR++ATEPPPSQE
Sbjct: 372 ASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQE 431
Query: 476 REPPAEPSIYAPLAIH 491
PAEPS+YA LAIH
Sbjct: 432 GASPAEPSVYATLAIH 447
Score = 229 bits (584), Expect = 4e-60
Identities = 118/223 (52%), Positives = 144/223 (64%), Gaps = 1/223 (0%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M T + L+CLGLS+GPRT +QAG LPKPTLWAEP SVI+ G VT+WCQG LE EYRL
Sbjct: 1 MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKE P RQNPLEP KA+F IPS D AGRYRCYY +P GWS+PSDPLELV TG
Sbjct: 61 DKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGA 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
KP+L +V G S+TL C+S D F+L KE + + A QA F
Sbjct: 121 YSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEF 180
Query: 181 TLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPD 222
+ PV+ HGG YRC+ +H S S PSDPL+++++G + D
Sbjct: 181 PMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLED 223
Score = 51.6 bits (122), Expect = 2e-06
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 5/113 (4%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL--PWARKRQNP 74
P V G KPTL A P+ ++ GK VTL CQ + + L KE P R
Sbjct: 112 PLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEH 171
Query: 75 LEPGAKAKFHIPSTVYDSAGRYRCYYETPAGW---SEPSDPLELVATGVSRKP 124
+A+F + G YRC+ S PSDPLEL+ +G P
Sbjct: 172 GAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDP 224
>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 1 [Homo sapiens]
Length = 448
Score = 350 bits (899), Expect = 1e-96
Identities = 210/437 (48%), Positives = 254/437 (58%), Gaps = 62/437 (14%)
Query: 112 PLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQP 171
P + G KP+L GSV++ G S+T+ C+ + + L KE Q P
Sbjct: 17 PRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE--ESPAPWDRQNP 74
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPG 231
++A F++ ++ + G+YRCY + WS PSDPL++++ G P LS P
Sbjct: 75 LEPKNKARFSIPSMTEDYAGRYRCY--YRSPVGWSQPSDPLELVMTGAYSK-PTLSALPS 131
Query: 232 PKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGG 291
P V SG++VTLLCQS +DTF L KE AAHP L L+S++ + +HQAEF MSPVTS GG
Sbjct: 132 PLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGG 191
Query: 292 TYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQ 351
TYRC+S+ YLLS PS P EL+VSG DP SPT S T AGPEDQPL PTG P
Sbjct: 192 TYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPH 251
Query: 352 SGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRT----SAHFYRPAGAAGPEPKD 407
SGL RH V+ GV V +LLL LLLFLLL+H Q KHRT A F RP GAA PEPKD
Sbjct: 252 SGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADFQRPPGAAEPEPKD 311
Query: 408 QGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDAR------------------------ 443
GLQ+R+SP AD+Q E AAVK+TQP+DGVEMD R
Sbjct: 312 GGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRQSPHDEDPQAVTYAKVKHSRPRRE 371
Query: 444 -----------------------------AAASEAPQDVTYAQLHSLTLRREATEPPPSQ 474
AAASEAPQDVTYAQLHS TLR++ATEPPPSQ
Sbjct: 372 MASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQ 431
Query: 475 EREPPAEPSIYAPLAIH 491
E PAEPS+YA LAIH
Sbjct: 432 EGASPAEPSVYATLAIH 448
Score = 229 bits (584), Expect = 4e-60
Identities = 118/223 (52%), Positives = 144/223 (64%), Gaps = 1/223 (0%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M T + L+CLGLS+GPRT +QAG LPKPTLWAEP SVI+ G VT+WCQG LE EYRL
Sbjct: 1 MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKE P RQNPLEP KA+F IPS D AGRYRCYY +P GWS+PSDPLELV TG
Sbjct: 61 DKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGA 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANF 180
KP+L +V G S+TL C+S D F+L KE + + A QA F
Sbjct: 121 YSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEF 180
Query: 181 TLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPD 222
+ PV+ HGG YRC+ +H S S PSDPL+++++G + D
Sbjct: 181 PMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLED 223
Score = 51.6 bits (122), Expect = 2e-06
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 5/113 (4%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL--PWARKRQNP 74
P V G KPTL A P+ ++ GK VTL CQ + + L KE P R
Sbjct: 112 PLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEH 171
Query: 75 LEPGAKAKFHIPSTVYDSAGRYRCYYETPAGW---SEPSDPLELVATGVSRKP 124
+A+F + G YRC+ S PSDPLEL+ +G P
Sbjct: 172 GAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDP 224
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 340 bits (873), Expect = 1e-93
Identities = 198/371 (53%), Positives = 235/371 (63%), Gaps = 21/371 (5%)
Query: 28 KPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQNPLEPGAKAKFH 84
+PTL A P+ V+ G VTL C L + L +EG L W +A F
Sbjct: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
Query: 85 IPSTVYDSAGRYRCY-YE--TPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLT 141
+ + + G +RCY YE TP WSEPSDPL+L+ +GVSRKPSLL QG VV G +LT
Sbjct: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
Query: 142 LQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNL 201
LQC SDVGY + LYKEG L Q G+QPQAGLSQANFTL PVSRS+GGQYRCYGAHN+
Sbjct: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNV 301
Query: 202 SPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAA 261
S WSAPSDPLDILIAG I D P+LSVQPGP V SGE VTLLCQSW + TF LTKEGAA
Sbjct: 302 SSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAA 361
Query: 262 HPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPS 321
HPPL L+S Y ++++QAEF MSPVTSA GTYRCY + S PYLLS PS P ELVVSG +
Sbjct: 362 HPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGAT 421
Query: 322 GDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFL-LLFLLL 380
T PA + T L + + + + VA ++LLFL +L
Sbjct: 422 ---------ETLNPAQKKSDSKTAPHLQDYT-----VENLIRMGVAGLVLLFLGILLFEA 467
Query: 381 RHRHQSKHRTS 391
+H +S R S
Sbjct: 468 QHSQRSPPRCS 478
Score = 266 bits (680), Expect = 3e-71
Identities = 162/353 (45%), Positives = 207/353 (58%), Gaps = 7/353 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MTL L+ L+ GLS+GPRT VQA LPKP LWAEP VI PVT+WCQG LE + YRL
Sbjct: 1 MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120
DKEG +R LE K K IPS +++ AGRY CYY++PAGWSEPSDPLELV T
Sbjct: 61 DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY 120
Query: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQAN 179
SR P+L VV G ++TL+C S +G F L +EG+H L + Q G QA
Sbjct: 121 SR-PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
Query: 180 FTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
F +GP++ S+ G +RCYG N +P WS PSDPL +L++G + P+L GP V GE
Sbjct: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSG-VSRKPSLLTLQGPVVTPGE 238
Query: 239 NVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298
N+TL C S + L KEGA P + Q+ QA F++SPV+ + GG YRCY A
Sbjct: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
Query: 299 IRSYPYLLSSPSYPQELVVSGPSGD-PSLSPTGSTPTPAGPEDQPLTPTGLDP 350
+ S+PS P +++++G D PSLS PT E L DP
Sbjct: 299 -HNVSSEWSAPSDPLDILIAGQISDRPSLS-VQPGPTVTSGEKVTLLCQSWDP 349
>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform a [Homo sapiens]
Length = 483
Score = 331 bits (848), Expect = 1e-90
Identities = 199/365 (54%), Positives = 226/365 (61%), Gaps = 15/365 (4%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE 76
P V G KPTL A P+ V+ G VTL C + + + L KEG +R N
Sbjct: 111 PLELVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHS 170
Query: 77 PGAKAKFHIPSTVYDSAGR---YRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
+ I S S R YRCY +P WS PSD LEL+ GVS+KPSL +
Sbjct: 171 HARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQP 230
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G +VA G SLTLQC SDVGYD FVLYKEGE D +Q G QPQAGLSQANFTLGPVS SHG
Sbjct: 231 GPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHG 290
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCY AHNLS WSAPSDPLDILI G D P+LSVQP P VA G+NVTLLCQS Q
Sbjct: 291 GQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQF 350
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
TF LTKEGA HPPL L+S++Q+ ++QAEF M PVTSA GTYRCYS++ S PYLLS PS
Sbjct: 351 HTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPS 410
Query: 311 YPQELVVS--GPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAF 368
P ELVVS + PS + T ST T G Q T L +GV V V
Sbjct: 411 DPLELVVSEAAETLSPSQNKTDSTTTSLGQHPQDYTVENL-------IRMGVAGLVLVVL 463
Query: 369 VLLLF 373
+LLF
Sbjct: 464 GILLF 468
Score = 266 bits (679), Expect = 4e-71
Identities = 164/332 (49%), Positives = 203/332 (61%), Gaps = 10/332 (3%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG L+ EEY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 61 DKE--GLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVAT 118
+E W R+ Q EPG +F IPS ++ AGRY C Y + SE SDPLELV T
Sbjct: 61 YRENKSASWVRRIQ---EPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVT 117
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQ 177
G KP+L VV GG++TLQC S V +D F+L KEGE + Q A G S
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSW 177
Query: 178 ANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
A F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 178 AIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPG-VSKKPSLSVQPGPMVAP 236
Query: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
GE++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRCY
Sbjct: 237 GESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCY 296
Query: 297 SAIRSYPYLLSSPSYPQELVVSGPSGD-PSLS 327
SA + S+PS P +++++G D PSLS
Sbjct: 297 SA-HNLSSEWSAPSDPLDILITGQFYDRPSLS 327
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/121 (31%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 217 AGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRH 276
AG +P P L +PG + G VTL CQ Q + + L +E + + + Q
Sbjct: 23 AGHLPK-PTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWV---RRIQEPGK 78
Query: 277 QAEFSMSPVTSAQGGTYRC--YSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPT 334
+F + +T G Y C YS S Y S P ELVV+G P+LS + P+
Sbjct: 79 NGQFPIPSITWEHAGRYHCQYYSHNHSSEY-----SDPLELVVTGAYSKPTLS---ALPS 130
Query: 335 P 335
P
Sbjct: 131 P 131
>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform b [Homo sapiens]
Length = 466
Score = 323 bits (827), Expect = 3e-88
Identities = 183/312 (58%), Positives = 206/312 (66%), Gaps = 6/312 (1%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE 76
P V G KPTL A P+ V+ G VTL C + + + L KEG +R N
Sbjct: 111 PLELVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHS 170
Query: 77 PGAKAKFHIPSTVYDSAGR---YRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
+ I S S R YRCY +P WS PSD LEL+ GVS+KPSL +
Sbjct: 171 HARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQP 230
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G +VA G SLTLQC SDVGYD FVLYKEGE D +Q G QPQAGLSQANFTLGPVS SHG
Sbjct: 231 GPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHG 290
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRCY AHNLS WSAPSDPLDILI G D P+LSVQP P VA G+NVTLLCQS Q
Sbjct: 291 GQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQF 350
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
TF LTKEGA HPPL L+S++Q+ ++QAEF M PVTSA GTYRCYS++ S PYLLS PS
Sbjct: 351 HTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPS 410
Query: 311 YPQELVVSGPSG 322
P ELVVS G
Sbjct: 411 DPLELVVSASLG 422
Score = 266 bits (679), Expect = 4e-71
Identities = 164/332 (49%), Positives = 203/332 (61%), Gaps = 10/332 (3%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+GPRT VQAG LPKPTLWAEP SVI +G PVTL CQG L+ EEY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 61 DKE--GLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVAT 118
+E W R+ Q EPG +F IPS ++ AGRY C Y + SE SDPLELV T
Sbjct: 61 YRENKSASWVRRIQ---EPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVT 117
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQ 177
G KP+L VV GG++TLQC S V +D F+L KEGE + Q A G S
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSW 177
Query: 178 ANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
A F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 178 AIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPG-VSKKPSLSVQPGPMVAP 236
Query: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
GE++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRCY
Sbjct: 237 GESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCY 296
Query: 297 SAIRSYPYLLSSPSYPQELVVSGPSGD-PSLS 327
SA + S+PS P +++++G D PSLS
Sbjct: 297 SA-HNLSSEWSAPSDPLDILITGQFYDRPSLS 327
Score = 106 bits (264), Expect = 5e-23
Identities = 69/207 (33%), Positives = 109/207 (52%), Gaps = 6/207 (2%)
Query: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQN--PLEPGAKA 81
G KP+L +P ++A G+ +TL C + + + L KEG +R P ++A
Sbjct: 219 GVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQA 278
Query: 82 KFHIPSTVYDSAGRYRCY--YETPAGWSEPSDPLELVATG-VSRKPSLLIPQGSVVARGG 138
F + G+YRCY + + WS PSDPL+++ TG +PSL + VA G
Sbjct: 279 NFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGK 338
Query: 139 SLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGA 198
++TL C+S + F+L KEG + QA +QA F +GPV+ +H G YRCY +
Sbjct: 339 NVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSS 398
Query: 199 HNLSPRW-SAPSDPLDILIAGLIPDIP 224
+ +P S PSDPL+++++ + P
Sbjct: 399 LSSNPYLLSLPSDPLELVVSASLGQHP 425
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/121 (31%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 217 AGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRH 276
AG +P P L +PG + G VTL CQ Q + + L +E + + + Q
Sbjct: 23 AGHLPK-PTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWV---RRIQEPGK 78
Query: 277 QAEFSMSPVTSAQGGTYRC--YSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPT 334
+F + +T G Y C YS S Y S P ELVV+G P+LS + P+
Sbjct: 79 NGQFPIPSITWEHAGRYHCQYYSHNHSSEY-----SDPLELVVTGAYSKPTLS---ALPS 130
Query: 335 P 335
P
Sbjct: 131 P 131
>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 1 [Homo sapiens]
Length = 489
Score = 315 bits (807), Expect = 6e-86
Identities = 189/371 (50%), Positives = 225/371 (60%), Gaps = 13/371 (3%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PWARKRQN 73
P V G KPTL A P+ V+ G VTL C + + L KEG P Q
Sbjct: 113 PLELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQP 172
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQ 130
++A F + YRCY +P WS PSD LEL+ GVS+KPSL +
Sbjct: 173 RTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQP 232
Query: 131 GSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHG 190
G +VA G SLTLQC SDV YD FVLYKEGE D +Q G QPQAGLSQANFTLGPVSRS+G
Sbjct: 233 GPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYG 292
Query: 191 GQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQI 250
GQYRC GA+NLS WSAPSDPLDILIAG P +SV PGP VASGENVTLLCQSW
Sbjct: 293 GQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPF 352
Query: 251 DTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPS 310
TF LTK GAA PL L+S ++ ++QAEF MSPVTSA GTYRCY ++ S PYLLS PS
Sbjct: 353 HTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPS 412
Query: 311 YPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTP----TGLDPQSGLGRHLGVVTGVSV 366
EL+VSG + +LSP + L+P T PQ +L + G++
Sbjct: 413 DSLELMVSGAA--ETLSPPQNKSDSKAGAANTLSPSQNKTASHPQDYTVENL-IRMGIAG 469
Query: 367 AFVLLLFLLLF 377
+++L +LLF
Sbjct: 470 LVLVVLGILLF 480
Score = 277 bits (709), Expect = 1e-74
Identities = 172/353 (48%), Positives = 216/353 (61%), Gaps = 19/353 (5%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT ++VLICL LS+GPRT VQAGTLPKPTLWAEP SVI +G PVTLWCQG LET+EYRL
Sbjct: 1 MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60
Query: 61 --DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYET-PAGWSEPSDPLELVA 117
+K+ PW + P E K +F IPS ++ GRYRC+Y + AGWSEPSDPLELV
Sbjct: 61 YREKKTAPWITR--IPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVV 118
Query: 118 TGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLS 176
TG KP+L VV GG++TL C S V + F+L KEGE + Q QP+ G S
Sbjct: 119 TGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWS 178
Query: 177 QANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVA 235
+A F++GPVS S YRCY + SP WS PSD L++L+ G + P+LSVQPGP VA
Sbjct: 179 RAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLG-VSKKPSLSVQPGPIVA 237
Query: 236 SGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRC 295
GE++TL C S D F L KEG + Q+ QA F++ PV+ + GG YRC
Sbjct: 238 PGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRC 297
Query: 296 YSAIRSYPYLLSS----PSYPQELVVSGP-SGDPSLSPTGSTPTPAGPEDQPL 343
A Y LSS PS P +++++G G P +S PT A E+ L
Sbjct: 298 SGA-----YNLSSEWSAPSDPLDILIAGQFRGRPFIS-VHPGPTVASGENVTL 344
>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
(without TM domain), member 3 [Homo sapiens]
Length = 439
Score = 313 bits (801), Expect = 3e-85
Identities = 180/324 (55%), Positives = 209/324 (64%), Gaps = 8/324 (2%)
Query: 11 LGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGL---PW 67
L S P V G KPTL A P+ V+ G VT+ C + + + L KEG P
Sbjct: 107 LSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQ 166
Query: 68 ARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCY-YET--PAGWSEPSDPLELVATGVSRKP 124
+ ++A F + YRCY Y++ P WS PSD L L+ GVS+KP
Sbjct: 167 CLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKP 226
Query: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGP 184
SL + G VVA G LT QC SD GYD FVLYKE D +Q G+QPQAGLSQANFTLGP
Sbjct: 227 SLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGP 286
Query: 185 VSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLC 244
VSRS+GGQY C GA+NLS WSAPSDPLDILI G I P LSV+PGP VASGENVTLLC
Sbjct: 287 VSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLC 346
Query: 245 QSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPY 304
QS + TF LTKEGAA PL LKSK QS+++QAEF MSPVTSA GTYRCY ++ S PY
Sbjct: 347 QSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPY 406
Query: 305 LLSSPSYPQELVVSGPSGDPSLSP 328
LL+ PS P ELVVSG + +LSP
Sbjct: 407 LLTHPSDPLELVVSGAA--ETLSP 428
Score = 242 bits (618), Expect = 5e-64
Identities = 158/350 (45%), Positives = 197/350 (56%), Gaps = 13/350 (3%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+ PRT VQAG LPKPTLWAEP SVI +G PVTL CQG LET+EY L
Sbjct: 1 MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYET-PAGWSEPSDPLELVATG 119
+E + P E K +F I S ++ AGRY C Y + G SE SDPLELV TG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVTG 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
KP+L VV GG++T+QC S V +D F+L KEGE + Q A G S+A
Sbjct: 121 AYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 180
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCYG + +P WS PSD L +L+ G + P+LSVQPGP VA G
Sbjct: 181 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPG-VSKKPSLSVQPGPVVAPG 239
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E +T C S D F L KE + Q+ QA F++ PV+ + GG Y C
Sbjct: 240 EKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSG 299
Query: 298 AIRSYPYLLSS----PSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343
A Y LSS PS P +++++G PT A E+ L
Sbjct: 300 A-----YNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTL 344
>gi|134268642 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 2 precursor [Homo
sapiens]
Length = 455
Score = 232 bits (591), Expect = 7e-61
Identities = 166/494 (33%), Positives = 234/494 (47%), Gaps = 69/494 (13%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M+LT+ + C+G + G KP L A P++V+ RG V L C + L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60
Query: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRCYYETP---AGWSEPSDPLEL 115
KE + P+ G + F + AG YRC P GWS PS+PL +
Sbjct: 61 YKED-----RSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115
Query: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGL 175
+ TG RKPSLL G ++ G ++ LQC SDV ++ F L++EG + Q G+
Sbjct: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175
Query: 176 SQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKV 234
S+ANF++GP+ G YRCYG+ SP + SAPSDPLDI+I GL + P+LS QPGP V
Sbjct: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTV 234
Query: 235 ASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYR 294
+GENVTL C SW D + L++EG AH + QA+F + P T GGTYR
Sbjct: 235 QAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPAT--HGGTYR 292
Query: 295 CYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGL 354
C+ + R+ P + S+ S P + V+G +P+ S P+P P +SG+
Sbjct: 293 CFGSFRALPCVWSNSSDPLLVSVTG-------NPSSSWPSPTEPSS----------KSGI 335
Query: 355 GRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRA 414
RHL V+ G SV L + LL FLL R K
Sbjct: 336 CRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKK--------------------------- 368
Query: 415 SPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQ 474
NAAV D +P ++ + + + PQ+VTYAQL + P +
Sbjct: 369 -----------NAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417
Query: 475 EREPPAEPSIYAPL 488
+ P + S+Y L
Sbjct: 418 PKTPLTDTSVYTEL 431
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 228 bits (581), Expect = 1e-59
Identities = 163/494 (32%), Positives = 236/494 (47%), Gaps = 69/494 (13%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M+L + + C+GL + R G KP L A P++V+ RG VTL C + L
Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRC---YYETPAGWSEPSDPLEL 115
KE + P+ G + F++ AG Y C + +P GWS PS+P+ +
Sbjct: 61 YKED-----RIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115
Query: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGL 175
+ TG RKPSLL G +V G + LQC SD+ ++ F L+KEG Q G+
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175
Query: 176 SQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKV 234
S+ANF++GP+ + G YRCYG+ +P + SAPSDPLDI++ G + P+LS QPGPKV
Sbjct: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPY-EKPSLSAQPGPKV 234
Query: 235 ASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYR 294
+GE+VTL C S D + L++EG AH + + QA+F + P T GGTYR
Sbjct: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYR 292
Query: 295 CYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGL 354
C+ + R PY S PS P + V+G +P+ S P+P P + SG
Sbjct: 293 CFGSFRHSPYEWSDPSDPLLVSVTG-------NPSSSWPSPTEPSSK----------SGN 335
Query: 355 GRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRA 414
RHL ++ G SV +L + LLLF LL +K
Sbjct: 336 PRHLHILIGTSVVIILFI-LLLFFLLHLWCSNKK-------------------------- 368
Query: 415 SPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQ 474
NAAV D +P ++ + + P++VTYAQL + P +
Sbjct: 369 -----------NAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417
Query: 475 EREPPAEPSIYAPL 488
+ PP + +Y L
Sbjct: 418 PKTPPTDTILYTEL 431
>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 3 [Homo sapiens]
Length = 265
Score = 225 bits (573), Expect = 8e-59
Identities = 124/236 (52%), Positives = 153/236 (64%), Gaps = 3/236 (1%)
Query: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
L VL+CLGLS+GPRT VQAG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 23 LMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 82
Query: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 83 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 142
Query: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 143 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 202
Query: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
PV+ SH RCYG+ ++ WS PSD L+I ++G + + ++Q G + GE
Sbjct: 203 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQ-GSQTGCGE 257
Score = 114 bits (285), Expect = 2e-25
Identities = 81/228 (35%), Positives = 113/228 (49%), Gaps = 8/228 (3%)
Query: 112 PLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQP 171
P V G K +L GSV++RG S+T++C+ + + L KEG + Q P
Sbjct: 35 PRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 92
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQP 230
++A F++ ++ H G+YRCY SP WS PSDPL++++ G + P LS P
Sbjct: 93 LEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFY-NKPTLSALP 148
Query: 231 GPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY-QSYRHQAEFSMSPVTSAQ 289
P V SGENVTL C S + D F LT+EG L S+ S + QA F + PVT +
Sbjct: 149 SPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSH 208
Query: 290 GGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 337
RCY + R + S PS E+ VSG S + T G
Sbjct: 209 RWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCG 256
>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 1 [Homo sapiens]
Length = 299
Score = 224 bits (570), Expect = 2e-58
Identities = 120/216 (55%), Positives = 144/216 (66%), Gaps = 2/216 (0%)
Query: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
L VL+CLGLS+GPRT VQAG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 23 LMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 82
Query: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 83 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 142
Query: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 143 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 202
Query: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAG 218
PV+ SH RCYG+ ++ WS PSD L+I ++G
Sbjct: 203 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 238
Score = 115 bits (287), Expect = 1e-25
Identities = 81/220 (36%), Positives = 115/220 (52%), Gaps = 10/220 (4%)
Query: 112 PLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQP 171
P V G K +L GSV++RG S+T++C+ + + L KEG + Q P
Sbjct: 35 PRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 92
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQP 230
++A F++ ++ H G+YRCY SP WS PSDPL++++ G + P LS P
Sbjct: 93 LEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFY-NKPTLSALP 148
Query: 231 GPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQ-SYRHQAEFSMSPVTSAQ 289
P V SGENVTL C S + D F LT+EG L S+ S + QA F + PVT +
Sbjct: 149 SPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSH 208
Query: 290 GGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPT 329
RCY + R + S PS E+ VSG + +LSP+
Sbjct: 209 RWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA--DNLSPS 246
Score = 55.1 bits (131), Expect = 1e-07
Identities = 41/117 (35%), Positives = 55/117 (47%), Gaps = 15/117 (12%)
Query: 226 LSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHP-----PLCLKSKYQSYRHQAEF 280
L +PG ++ G +VT+ CQ + + L KEG+ P PL K+K A F
Sbjct: 49 LWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNK-------ARF 101
Query: 281 SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 337
S+ +T G YRCY P S PS P ELVV+G P+LS S +G
Sbjct: 102 SIPSMTEHHAGRYRCYYYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSG 155
Score = 47.8 bits (112), Expect = 2e-05
Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQN 73
P V G KPTL A P+ V+ G+ VTL C L + + L +EG L W Q
Sbjct: 130 PLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 189
Query: 74 PLEPGAKAKFHIPSTVYDSAGRYRCYYETP---AGWSEPSDPLELVATGVS 121
+A F + RCY WSEPSD LE+ +G +
Sbjct: 190 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 240
>gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like
receptor, partial [Homo sapiens]
Length = 256
Score = 218 bits (554), Expect = 1e-56
Identities = 133/258 (51%), Positives = 160/258 (62%), Gaps = 5/258 (1%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
MT L+VLICLGLS+ PRT VQAG LPKPTLWAEP SVI +G PVTL CQG LET+EY L
Sbjct: 1 MTPILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 61 DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYET-PAGWSEPSDPLELVATG 119
+E + P E K +F I S ++ AGRY C Y + AG SE SDPLELV T
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA 120
Query: 120 VSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA-GLSQA 178
S KP+L VV GG++T+QC S V +D F+L KEGE + Q A G S+A
Sbjct: 121 YS-KPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 179
Query: 179 NFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
F++GPVS S YRCYG + +P WS PSD L +L+ G + P+LSVQPGP VA G
Sbjct: 180 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPG-VSKKPSLSVQPGPVVAPG 238
Query: 238 ENVTLLCQSWHQIDTFFL 255
E +T C S D F L
Sbjct: 239 EKLTFQCGSDPGYDRFVL 256
Score = 114 bits (284), Expect = 3e-25
Identities = 85/243 (34%), Positives = 118/243 (48%), Gaps = 12/243 (4%)
Query: 111 DPLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQ 170
DP V G KP+L GSV+ +G +TL+C+ + + LY+E + L +
Sbjct: 16 DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTAL--WITRI 73
Query: 171 PQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQ 229
PQ + + F + ++ H G+Y C YG+H S SDPL++++ P LS
Sbjct: 74 PQELVKKGQFPILSITWEHAGRYCCIYGSHTAG--LSESSDPLELVVTAYSK--PTLSAL 129
Query: 230 PGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKS-KYQSYRHQAEFSMSPVTSA 288
P P V SG NVT+ C S D F L KEG P CL S + +A FS+ PV+ +
Sbjct: 130 PSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPS 189
Query: 289 QGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLT-PTG 347
+ +YRCY PY+ S PS L+V G S PSLS P P + LT G
Sbjct: 190 RRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLS---VQPGPVVAPGEKLTFQCG 246
Query: 348 LDP 350
DP
Sbjct: 247 SDP 249
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 211 bits (538), Expect = 9e-55
Identities = 159/494 (32%), Positives = 227/494 (45%), Gaps = 94/494 (19%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M+L + + C+G + G KP L A P +V++ G+ VTL C+ L E+ L
Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
Query: 61 DKE-GLP----WARKRQNPLEPGAKAKFHIPSTVYDSAGRYRC---YYETPAGWSEPSDP 112
KE G+P + R +N G H AG YRC + +P GWS PS+P
Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAH--------AGTYRCCSSHPHSPTGWSAPSNP 112
Query: 113 LELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEG-EHDLVQGSGQQP 171
+ ++ TGV RKPSLL G +V G ++ LQC SDV ++ F+L++EG D ++ GQ
Sbjct: 113 VVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLH 172
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSVQP 230
AG SQ N+++GP++ + G YRC+G+ +L SAPSDPLDI++ GL P+LS QP
Sbjct: 173 DAG-SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGK-PSLSAQP 230
Query: 231 GPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQG 290
GP V +GENVTL C S D + L++E A + QA F + PVT G
Sbjct: 231 GPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVT--HG 288
Query: 291 GTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDP 350
G YRC+ + R+ P+ S PS P + V+G S
Sbjct: 289 GNYRCFGSFRALPHAWSDPSDPLPVSVTGNS----------------------------- 319
Query: 351 QSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGL 410
RHL V+ G SV + LL FLL R K
Sbjct: 320 -----RHLHVLIGTSVVIIPFAILLFFLLHRWCANKK----------------------- 351
Query: 411 QKRASPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEP 470
NA V D +P ++ + + PQ+VTYAQL+ +
Sbjct: 352 ---------------NAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITR 396
Query: 471 PPSQEREPPAEPSI 484
P + + PP + S+
Sbjct: 397 PSQRPKTPPTDTSV 410
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 211 bits (536), Expect = 2e-54
Identities = 143/387 (36%), Positives = 201/387 (51%), Gaps = 31/387 (8%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M L + + C+GL + R G KP L A P++V+ RG VTL C + L
Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRC---YYETPAGWSEPSDPLEL 115
KE + P+ G + F++ AG Y C + +P GWS PS+P+ +
Sbjct: 61 YKED-----RIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Query: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGL 175
+ TG RKPSLL G +V G + LQC SD+ ++ F L+KE Q G+
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
Query: 176 SQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKV 234
S+ANF++G + R+ G YRCYG+ +P + SAPSDPLDI++ GL + P+LS QPGPKV
Sbjct: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLY-EKPSLSAQPGPKV 234
Query: 235 ASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYR 294
+GE+VTL C S D + L++EG AH + + QA+F + P T GGTYR
Sbjct: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYR 292
Query: 295 CYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGL 354
C+ + R PY S PS P + V+G +P+ S P+P P +SG
Sbjct: 293 CFGSFRHSPYEWSDPSDPLLVSVTG-------NPSSSWPSPTEPSS----------KSGN 335
Query: 355 GRHLGVVTGVSVAFVLLLFLLLFLLLR 381
RHL ++ G SV + LL FLL R
Sbjct: 336 LRHLHILIGTSVVKIPFTILLFFLLHR 362
>gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 4 [Homo sapiens]
Length = 253
Score = 197 bits (502), Expect = 1e-50
Identities = 114/236 (48%), Positives = 142/236 (60%), Gaps = 15/236 (6%)
Query: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
Query: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
Query: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
Query: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
PV+ SH RCYG+ ++ WS PSD L+I ++G + + ++Q G + GE
Sbjct: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQ-GSQTGCGE 245
Score = 117 bits (292), Expect = 3e-26
Identities = 86/249 (34%), Positives = 120/249 (48%), Gaps = 21/249 (8%)
Query: 104 AGWSEPSDPLE-------------LVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGY 150
A WS PS L+ L+ G K +L GSV++RG S+T++C+ +
Sbjct: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
Query: 151 DIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPS 209
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PS
Sbjct: 62 QEYRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPS 116
Query: 210 DPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKS 269
DPL++++ G + P LS P P V SGENVTL C S + D F LT+EG L S
Sbjct: 117 DPLELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
Query: 270 KY-QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSP 328
+ S + QA F + PVT + RCY + R + S PS E+ VSG S
Sbjct: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSST 235
Query: 329 TGSTPTPAG 337
+ T G
Sbjct: 236 IQGSQTGCG 244
>gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 2 [Homo sapiens]
Length = 287
Score = 196 bits (499), Expect = 3e-50
Identities = 110/216 (50%), Positives = 133/216 (61%), Gaps = 14/216 (6%)
Query: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
Query: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
Query: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
Query: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAG 218
PV+ SH RCYG+ ++ WS PSD L+I ++G
Sbjct: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
Score = 117 bits (294), Expect = 2e-26
Identities = 86/241 (35%), Positives = 122/241 (50%), Gaps = 23/241 (9%)
Query: 104 AGWSEPSDPLE-------------LVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGY 150
A WS PS L+ L+ G K +L GSV++RG S+T++C+ +
Sbjct: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
Query: 151 DIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPS 209
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PS
Sbjct: 62 QEYRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPS 116
Query: 210 DPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKS 269
DPL++++ G + P LS P P V SGENVTL C S + D F LT+EG L S
Sbjct: 117 DPLELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
Query: 270 KY-QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSP 328
+ S + QA F + PVT + RCY + R + S PS E+ VSG + +LSP
Sbjct: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA--DNLSP 233
Query: 329 T 329
+
Sbjct: 234 S 234
Score = 55.1 bits (131), Expect = 1e-07
Identities = 41/117 (35%), Positives = 55/117 (47%), Gaps = 15/117 (12%)
Query: 226 LSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHP-----PLCLKSKYQSYRHQAEF 280
L +PG ++ G +VT+ CQ + + L KEG+ P PL K+K A F
Sbjct: 37 LWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNK-------ARF 89
Query: 281 SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 337
S+ +T G YRCY P S PS P ELVV+G P+LS S +G
Sbjct: 90 SIPSMTEHHAGRYRCYYYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSG 143
>gi|71143139 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 2 [Homo sapiens]
Length = 341
Score = 186 bits (472), Expect = 4e-47
Identities = 128/372 (34%), Positives = 182/372 (48%), Gaps = 61/372 (16%)
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH-DLVQGSGQQPQAGLSQ 177
GV RKPSLL G +V ++ LQC SDV + F+L++EG+ D + G+ G+S+
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82
Query: 178 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
ANF++GP+ + G YRCYG+ SP + SAPSDPLDI+I GL + P+LS QPGP V +
Sbjct: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVLA 141
Query: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
GE+VTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 142 GESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
Query: 297 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGR 356
+ R PY S+ S P + V+G +P+ S P+P P ++G R
Sbjct: 200 GSFRDSPYEWSNSSDPLLVSVTG-------NPSNSWPSPTEPSS----------ETGNPR 242
Query: 357 HLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASP 416
HL V+ G SV +L + LL FLL R K
Sbjct: 243 HLHVLIGTSVVIILFILLLFFLLHRWCCNKK----------------------------- 273
Query: 417 VADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQER 476
NA V D +P ++ + + PQ+VTYAQL+ + P + +
Sbjct: 274 ---------NAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPK 324
Query: 477 EPPAEPSIYAPL 488
PP + +Y L
Sbjct: 325 TPPTDIIVYTEL 336
Score = 120 bits (302), Expect = 2e-27
Identities = 81/229 (35%), Positives = 115/229 (50%), Gaps = 18/229 (7%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M+L + ++C+G + G KP+L A P ++ + V L C + + + L
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110
+EG K ++ L + +KA F I + D AG YRCY +P S PS
Sbjct: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115
Query: 111 DPLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQ 170
DPL++V TG+ KPSL G V G S+TL C S YD++ L +EGE + S
Sbjct: 116 DPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGP 175
Query: 171 PQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 218
G QA+F LGP +HGG YRC+G+ SP WS SDPL + + G
Sbjct: 176 KVNGTFQADFPLGPA--THGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
Length = 328
Score = 185 bits (470), Expect = 7e-47
Identities = 125/322 (38%), Positives = 177/322 (54%), Gaps = 22/322 (6%)
Query: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
M+L + + C+G + G KP L A P+ V++ G+ V L C+ L E+ L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60
Query: 61 DKE-GLP----WARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETP---AGWSEPSDP 112
KE G+P + R +N + G H AG YRC P GWS PS+P
Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAH--------AGTYRCRGSHPHFLTGWSAPSNP 112
Query: 113 LELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQP 171
L ++ TGV RKPSLL G +V ++ LQC SDV ++ F+L++EG+ +D ++ +G+
Sbjct: 113 LVIMVTGVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGEL- 171
Query: 172 QAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQP 230
G+S+ANF++G +++ G YRCYG+ SP + SAPSDPLDI+I GL P+LS QP
Sbjct: 172 HDGVSKANFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGK-PSLSAQP 230
Query: 231 GPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQG 290
P V +GE+VTL C S D + L++EG AH + QA F + P T G
Sbjct: 231 RPMVKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPAT--HG 288
Query: 291 GTYRCYSAIRSYPYLLSSPSYP 312
GTYRC+ + R PY S S P
Sbjct: 289 GTYRCFGSFRDSPYEWSDLSDP 310
Score = 125 bits (313), Expect = 1e-28
Identities = 80/220 (36%), Positives = 114/220 (51%), Gaps = 7/220 (3%)
Query: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 178
G KP L VV+ G + LQCRS +G++ F L KE + + + + +
Sbjct: 24 GGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSLSKEDGMPVPELYNR-----VFRN 78
Query: 179 NFTLGPVSRSHGGQYRCYGAH-NLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237
+GPV+ +H G YRC G+H + WSAPS+PL I++ G + P+L PGP V S
Sbjct: 79 TVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTG-VHRKPSLLAHPGPLVKSE 137
Query: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297
E V L C S + F L +EG + L L + +A FS+ +T GTYRCY
Sbjct: 138 ETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYG 197
Query: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 337
++ PY LS+PS P ++V++G G PSLS AG
Sbjct: 198 SVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAG 237
Score = 48.5 bits (114), Expect = 1e-05
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 7/107 (6%)
Query: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE 76
P V G KP+L A+P ++ G+ VTL C + Y L +EG A + + P
Sbjct: 212 PLDIVITGLCGKPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGE--AHELRFPAV 269
Query: 77 PGAKAKF--HIPSTVYDSAGRYRCY---YETPAGWSEPSDPLELVAT 118
P F + P G YRC+ ++P WS+ SDPL + T
Sbjct: 270 PKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSDLSDPLLVSVT 316
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,862,794
Number of Sequences: 37866
Number of extensions: 1334062
Number of successful extensions: 8204
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 167
Number of HSP's that attempted gapping in prelim test: 6807
Number of HSP's gapped (non-prelim): 732
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.