Guide to the Human Genome
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Search of human proteins with 42476070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
         (1091 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]                   2215   0.0  
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]                   2193   0.0  
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]                   2134   0.0  
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ...   100   8e-21
gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H...    79   2e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     60   9e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     60   9e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       60   1e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    57   7e-08
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    55   4e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   1e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          54   1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          54   1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          54   1e-06
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   52   2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 52   3e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             52   4e-06
gi|209862789 microtubule associated monoxygenase, calponin and L...    52   4e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 51   7e-06
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                51   7e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       51   7e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       50   1e-05
gi|50345997 E1A binding protein p300 [Homo sapiens]                    50   2e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    50   2e-05
gi|33286444 mastermind-like 2 [Homo sapiens]                           50   2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   2e-05
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    49   3e-05
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]           49   3e-05
gi|50345881 cytoplasmic polyadenylation element binding protein ...    49   3e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    49   3e-05

>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
          Length = 1091

 Score = 2215 bits (5739), Expect = 0.0
 Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)

Query: 1    MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
            MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
Sbjct: 1    MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60

Query: 61   WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
            WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
Sbjct: 61   WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120

Query: 121  VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
            VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
Sbjct: 121  VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180

Query: 181  LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
            LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
Sbjct: 181  LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240

Query: 241  KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
            KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
Sbjct: 241  KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300

Query: 301  NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
            NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
Sbjct: 301  NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360

Query: 361  LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
            LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
Sbjct: 361  LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420

Query: 421  LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
            LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
Sbjct: 421  LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480

Query: 481  GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
            GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
Sbjct: 481  GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540

Query: 541  EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 600
            EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
Sbjct: 541  EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 600

Query: 601  IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660
            IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
Sbjct: 601  IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660

Query: 661  QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720
            QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
Sbjct: 661  QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720

Query: 721  QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 780
            QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
Sbjct: 721  QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 780

Query: 781  PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 840
            PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
Sbjct: 781  PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 840

Query: 841  QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN 900
            QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN
Sbjct: 841  QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN 900

Query: 901  NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS 960
            NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS
Sbjct: 901  NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS 960

Query: 961  SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS 1020
            SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS
Sbjct: 961  SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS 1020

Query: 1021 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ 1080
            SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ
Sbjct: 1021 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ 1080

Query: 1081 QRGQGTMNPPH 1091
            QRGQGTMNPPH
Sbjct: 1081 QRGQGTMNPPH 1091


>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
          Length = 1137

 Score = 2193 bits (5682), Expect = 0.0
 Identities = 1091/1137 (95%), Positives = 1091/1137 (95%), Gaps = 46/1137 (4%)

Query: 1    MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
            MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
Sbjct: 1    MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60

Query: 61   WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
            WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
Sbjct: 61   WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120

Query: 121  VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
            VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
Sbjct: 121  VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180

Query: 181  LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
            LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
Sbjct: 181  LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240

Query: 241  KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
            KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
Sbjct: 241  KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300

Query: 301  NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
            NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
Sbjct: 301  NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360

Query: 361  LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
            LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
Sbjct: 361  LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420

Query: 421  LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
            LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
Sbjct: 421  LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480

Query: 481  GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
            GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
Sbjct: 481  GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540

Query: 541  EKPVVTFKENIKTREVNRDQGRSFPPKE-------------------------------- 568
            EKPVVTFKENIKTREVNRDQGRSFPPKE                                
Sbjct: 541  EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 600

Query: 569  --------------VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 614
                          VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS
Sbjct: 601  EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660

Query: 615  RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 674
            RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ
Sbjct: 661  RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 720

Query: 675  QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 734
            QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK
Sbjct: 721  QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 780

Query: 735  SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 794
            SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM
Sbjct: 781  SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 840

Query: 795  QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854
            QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV
Sbjct: 841  QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 900

Query: 855  FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 914
            FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS
Sbjct: 901  FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960

Query: 915  SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 974
            SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN
Sbjct: 961  SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 1020

Query: 975  HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1034
            HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT
Sbjct: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080

Query: 1035 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091
            WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1137


>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
          Length = 1049

 Score = 2134 bits (5530), Expect = 0.0
 Identities = 1049/1049 (100%), Positives = 1049/1049 (100%)

Query: 43   MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 102
            MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
Sbjct: 1    MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60

Query: 103  TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 162
            TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
Sbjct: 61   TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120

Query: 163  RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 222
            RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
Sbjct: 121  RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180

Query: 223  STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 282
            STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
Sbjct: 181  STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240

Query: 283  LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 342
            LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
Sbjct: 241  LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300

Query: 343  CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 402
            CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
Sbjct: 301  CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360

Query: 403  HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 462
            HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
Sbjct: 361  HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420

Query: 463  GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 522
            GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
Sbjct: 421  GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480

Query: 523  LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 582
            LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE
Sbjct: 481  LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 540

Query: 583  ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 642
            ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG
Sbjct: 541  ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600

Query: 643  VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 702
            VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP
Sbjct: 601  VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 660

Query: 703  AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 762
            AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG
Sbjct: 661  AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 720

Query: 763  PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 822
            PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE
Sbjct: 721  PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 780

Query: 823  FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 882
            FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS
Sbjct: 781  FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 840

Query: 883  SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 942
            SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
Sbjct: 841  SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 900

Query: 943  SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 1002
            SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
Sbjct: 901  SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 960

Query: 1003 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1062
            DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
Sbjct: 961  DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1020

Query: 1063 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091
            HPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1021 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1049


>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor
           [Homo sapiens]
          Length = 1419

 Score =  100 bits (249), Expect = 8e-21
 Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 16/243 (6%)

Query: 7   QYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFK 66
           Q L+ + +L  D    + G  ++   R  L  LY++ ++ D+E++ ++ V+Q LW +AF 
Sbjct: 591 QELQLSNLLSRDRISPE-GLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFY 649

Query: 67  NQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL 126
             I   +   K+    N  +++  L   L+  S F+  LLQ+L   +   L   +    +
Sbjct: 650 QVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAI 709

Query: 127 GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTS------QAESYYRHAAQ 180
                ++T   A++           Q C++  GDIARYR Q S      +A S+Y  A  
Sbjct: 710 RSKPLRKTVKYALIS---------AQRCMICQGDIARYREQASDTANYGKARSWYLKAQH 760

Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
           + P NG+PYNQLA+LA      L  ++YY RS+A   P   A  +L     +     +++
Sbjct: 761 IAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQM 820

Query: 241 KTK 243
           + K
Sbjct: 821 EKK 823



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 29/147 (19%)

Query: 249  FIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLL--FQKAFNSQQLVHVTVINLFQLH 306
            FI +F+  HG ++    +E    + EK+ ++F+ LL        S +++ +  IN+F +H
Sbjct: 892  FILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVH 951

Query: 307  H--LRD-FSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPL-------------QNE 350
            +  L+D FS E       Q   L     LA+F S L   C C L             Q++
Sbjct: 952  NSQLKDCFSEECRSVIQEQAAALG----LAMF-SLLVRRCTCLLKESAKAQLSSPEDQDD 1006

Query: 351  SQEESYNAYP------LPAVKVSMDWL 371
              +   +++       LP+VKV  DW+
Sbjct: 1007 QDDIKVSSFVPDLKELLPSVKVWSDWM 1033


>gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo
           sapiens]
          Length = 1016

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 29/225 (12%)

Query: 33  RQALQDLYQK-MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANL 91
           R  L++L  K M +  ++Y   +K E+ LW   +   I  ++   K+  +  RS ++   
Sbjct: 56  RNKLRELCVKLMFLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAY 111

Query: 92  SLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS-- 146
              L A  GFY  LL  + + + ++L C +  + +         T  ++   KP S+S  
Sbjct: 112 RTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHV---------TDPLIGCKKPVSASGK 162

Query: 147 ----CSYICQHCLVHLGDIARYRNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILA 196
                   C  CLV+LGD++RY+N+ +       AE +Y  A  + P  G P+NQL  LA
Sbjct: 163 EMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLA 222

Query: 197 SSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVK 241
            SK  ++  ++ Y R I  +  F  A  NL++   KA +   ++K
Sbjct: 223 GSKYYNVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLK 267



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%)

Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 407
           LPAVKV +DWLR  P +         Q +W  L  LLN             +  P  +DL
Sbjct: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713

Query: 408 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 460
                 P       LPE+  L+    LR + R  +F      ++  +E     +R   + 
Sbjct: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770

Query: 461 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 508
           S G +IA  Q  ++Q   EVG  + I +  +  L   ++A+  +  +E
Sbjct: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)

Query: 587  PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 645
            P+ +TP  +S     P+   G   P P   G  P +    PP     G GY   P G   
Sbjct: 373  PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426

Query: 646  PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 688
            P  +   +Q  A S  G       Q   PY QQ PSG              P P  Q P 
Sbjct: 427  PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484

Query: 689  QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 747
             S QPPSQ P     AQP+ Q   Q Q   L Q  Q P    P+    PPH      Y  
Sbjct: 485  YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536

Query: 748  ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 807
              ++ Q               P  QP Y Q         P  Q P  QQQP +      P
Sbjct: 537  QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568

Query: 808  MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 867
                    +    P+       + +  R    Q+ + D  G ++           P M  
Sbjct: 569  APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620

Query: 868  EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 926
             K   E  +  L S  SS   L+G   +       ++   V    ++SS   + +P+ +P
Sbjct: 621  SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680

Query: 927  ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 980
                    L  +   +P     PAS   S     SP +   + +P  PP+   +S+  P 
Sbjct: 681  FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 981  SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1035
             N   I       +R     +   P  G       SA S  + S  Q  T  G++
Sbjct: 741  MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)

Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 649
           P Q S+    P H   ++   P+R  +PPP   Y +  P   + GSG    AG   P   
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252

Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 706
             P++ + A +       S   ++QQR     G GP   G    QP +   L  L   P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303

Query: 707 A 707
           +
Sbjct: 304 S 304



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%)

Query: 558 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 617
           + Q +S PP+   SQ    + P     +      P+Q S +Q     HP + PP  S+P 
Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555

Query: 618 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 677
              P     P            PA    P T  Q  A+     Q Q+ +     YSQQR 
Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597

Query: 678 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 735
             P  ++Q    SQ  S   +TS       Q    L +Q+        + ++  L  G  
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654

Query: 736 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 794
                G      + +  +  NP Q         P   P+    + P     PS +  P  
Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705

Query: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854
             Q     + P  + P N  P   + P    DS    + N+S +AQ     +R  + P  
Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762

Query: 855 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 911
             P+      PR P    +         +S       G     Q  YP    +N +   N
Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822

Query: 912 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 967
             S+  A  ++P  A  +        G P  P   +LP            P+  N +++P
Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 21/186 (11%)

Query: 642  GVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSL 701
            G + P T    T   PAG     G Q+  P+   R     P     QQ+ PP        
Sbjct: 1432 GNAYPATATAATERRPAG-----GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486

Query: 702  PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQL-----W- 755
             +   AQ  +  Q +       +  ++  +  + P +H   +  +     ++      W 
Sbjct: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546

Query: 756  -----NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFE--PSLQPPVMQQQPLEKKMKPFPM 808
                  PP   GP   + P+ +P     Q P  +    P +  P    +P+E +  P   
Sbjct: 1547 SHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SK 1603

Query: 809  EPYNHN 814
             P+ H+
Sbjct: 1604 SPFLHS 1609



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 20/226 (8%)

Query: 671  PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730
            PYS+    G G +  GP+Q  P    P   +  +P       +   A  Q    P+    
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316

Query: 731  ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP--YYLQTQDPIKLFEP 787
             +  SP  +   QQ QQ        N    QG P G   P +Q   Y  Q Q+  +  + 
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDG 1375

Query: 788  SLQPPVM--------------QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMAD 833
            +  PP                Q QP ++++ P   +P +   +    P+    + Y  A 
Sbjct: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435

Query: 834  NRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELM 879
              +  A        G ++   F+  +D V   P   +    P ++M
Sbjct: 1436 PATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)

Query: 587  PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 645
            P+ +TP  +S     P+   G   P P   G  P +    PP     G GY   P G   
Sbjct: 373  PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426

Query: 646  PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 688
            P  +   +Q  A S  G       Q   PY QQ PSG              P P  Q P 
Sbjct: 427  PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484

Query: 689  QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 747
             S QPPSQ P     AQP+ Q   Q Q   L Q  Q P    P+    PPH      Y  
Sbjct: 485  YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536

Query: 748  ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 807
              ++ Q               P  QP Y Q         P  Q P  QQQP +      P
Sbjct: 537  QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568

Query: 808  MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 867
                    +    P+       + +  R    Q+ + D  G ++           P M  
Sbjct: 569  APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620

Query: 868  EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 926
             K   E  +  L S  SS   L+G   +       ++   V    ++SS   + +P+ +P
Sbjct: 621  SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680

Query: 927  ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 980
                    L  +   +P     PAS   S     SP +   + +P  PP+   +S+  P 
Sbjct: 681  FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 981  SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1035
             N   I       +R     +   P  G       SA S  + S  Q  T  G++
Sbjct: 741  MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)

Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 649
           P Q S+    P H   ++   P+R  +PPP   Y +  P   + GSG    AG   P   
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252

Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 706
             P++ + A +       S   ++QQR     G GP   G    QP +   L  L   P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303

Query: 707 A 707
           +
Sbjct: 304 S 304



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%)

Query: 558 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 617
           + Q +S PP+   SQ    + P     +      P+Q S +Q     HP + PP  S+P 
Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555

Query: 618 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 677
              P     P            PA    P T  Q  A+     Q Q+ +     YSQQR 
Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597

Query: 678 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 735
             P  ++Q    SQ  S   +TS       Q    L +Q+        + ++  L  G  
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654

Query: 736 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 794
                G      + +  +  NP Q         P   P+    + P     PS +  P  
Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705

Query: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854
             Q     + P  + P N  P   + P    DS    + N+S +AQ     +R  + P  
Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762

Query: 855 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 911
             P+      PR P    +         +S       G     Q  YP    +N +   N
Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822

Query: 912 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 967
             S+  A  ++P  A  +        G P  P   +LP            P+  N +++P
Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 46/199 (23%), Positives = 73/199 (36%), Gaps = 16/199 (8%)

Query: 671  PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730
            PYS+    G G +  GP+Q  P    P   +  +P       +   A  Q    P+    
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316

Query: 731  ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQPYYLQTQDPIKLFEPSL 789
             +  SP  +   QQ QQ        N    QG P G   P +Q    Q Q  +    P  
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375

Query: 790  QPPVMQQQPLE--------KKMKPFPMEPYNH-NPSEVKVPEFYWDSSY---SMADNRSV 837
            +P   +  P +        K  K  P  P +H  P+ V+ P    D ++   S+   + V
Sbjct: 1376 RPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPV 1435

Query: 838  MAQQANIDRRGKRSPGVFR 856
            + Q+  +  +   +P  +R
Sbjct: 1436 LKQRRRLTMKDIGTPEAWR 1454


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 93/385 (24%), Positives = 144/385 (37%), Gaps = 58/385 (15%)

Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685
           PPP    M          + P T LQ      A  Q Q  +Q    + QQ+ +      Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182

Query: 686 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 745
             QQ Q  +QQ       Q   Q   QLQ Q   QQQQ   K          HH   QQ 
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231

Query: 746 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805
           QQ    +QL    Q+Q  L +    +Q    Q Q  ++   P  QPP+ Q QP   +  P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287

Query: 806 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 861
             ++  +H       P+        +A N+       +Q   +  + +  PG     Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344

Query: 862 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL 912
                    V + P +  + ++ + + +  ++ +   G  ++Q   P   + +   G+ +
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPGQQV 402

Query: 913 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS--SNPSSLPSSP 970
            +       P  +PQ           P  PS   +S+ S+  + SP S   +PS  PS  
Sbjct: 403 QTPQSMPPPPQPSPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451

Query: 971 P----THNHNSVPFSNFGPIGTPDN 991
           P    T  + SVP  + GP+ TP N
Sbjct: 452 PVTARTPQNFSVP--SPGPLNTPVN 474



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 62/268 (23%), Positives = 97/268 (36%), Gaps = 39/268 (14%)

Query: 551 IKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 610
           ++ ++  + Q +    + +++Q  +++ P+ + +  P    P Q         H P   P
Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQP 305

Query: 611 PLP----SRPGFPPPTYVIPPPVAFSMGSG----YTFP--AGVSVPGTFLQPTAH----- 655
             P    ++P   PP     P V+ +        YT P    V  P    QP        
Sbjct: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365

Query: 656 -------SPAGNQVQAG---KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 705
                  + A   V  G    QS +P     PS PG   Q P QS PP  QP +  P QP
Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLPMLSS-PS-PGQQVQTP-QSMPPPPQP-SPQPGQP 421

Query: 706 TAQSTSQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQ 759
           ++Q  S +     +    SP+  +P+    P   P  +   Q     +   L    NP  
Sbjct: 422 SSQPNSNVS----SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477

Query: 760 VQGPLGKIMPVKQPYYLQTQDPIKLFEP 787
           V  P G     +Q Y  + +   K  EP
Sbjct: 478 VMSPAGSSQAEEQQYLDKLKQLSKYIEP 505



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 48/225 (21%), Positives = 80/225 (35%), Gaps = 14/225 (6%)

Query: 565 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 624
           PP  V+ Q + ++T V  A+   +     Q S S    +  P     + +    PPP   
Sbjct: 357 PP--VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP 414

Query: 625 IPPPVAFSMGSGYTFPAG-VSVPGTFLQPTAHSPAGNQVQAGKQSHI----PYSQQRPSG 679
            P P   S        +G    P +FL   +  P+ + V A    +     P     P  
Sbjct: 415 SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVN 474

Query: 680 PGPMNQGPQQSQPPSQQPLTSLP-----AQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 734
           P  +      SQ   QQ L  L       +P  +  +++      ++  S  K++  +  
Sbjct: 475 PSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILT 534

Query: 735 SPPHHSGFQQYQQAD-ASKQLWNPPQV-QGPLGKIMPVKQPYYLQ 777
            P      +  Q+ + A ++L N   V   P   + P KQ Y  Q
Sbjct: 535 DPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQ 579


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 147/619 (23%), Positives = 220/619 (35%), Gaps = 122/619 (19%)

Query: 433  NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL 492
            +LD +K    + G+K G+   I Q R  S+     ++ P  I+ + E  K   + E+   
Sbjct: 619  SLDINK----LPGEKLGRVVHIIQSREPSL----KNSNPDEIEIDFETLKPSTLRELERY 670

Query: 493  ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK 552
            +     + ++     +   ++ +A  GS  +K   S+    S+   + +       E+ +
Sbjct: 671  VTSCLRKKRK----PQAEKVDVIA--GSSKMKGFSSSESESSSESSSSDS------EDSE 718

Query: 553  TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 612
            T    + + +  P +E K         + +A   PV Q P                 PP 
Sbjct: 719  TEMAPKSKKKGHPGREQKKHHHHHHQQMQQA-PAPVPQQP-----------------PPP 760

Query: 613  PSRPGFPPP----TYVIPPPVAFSMGSGYTFPAGVSVPGTF-------LQP----TAHSP 657
            P +P  PPP        PPP   SM      PA  S P  F       L+P    +   P
Sbjct: 761  PQQPPPPPPPQQQQQPPPPPPPPSMPQ-QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP 819

Query: 658  AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP--SQQPLTSLP----AQPTAQSTS 711
             G+  Q     H+P    +P  P  + Q P+ S PP  +Q  + S P    A P   S  
Sbjct: 820  IGHFTQ--PILHLP----QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873

Query: 712  QLQVQALTQQQQSPTKAVPALGKSP--PHHSGFQQYQQADASKQLWNPP----QVQGPLG 765
              +  AL  +   P    PAL ++P  P     Q  Q     ++   PP    Q+Q  L 
Sbjct: 874  SNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933

Query: 766  KIMPVKQPYYL------QTQDPIKL---FEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS 816
            ++  V+ P  L      Q+Q P  L     PS+Q  + QQ P     +P P     H P 
Sbjct: 934  QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993

Query: 817  EVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEK------- 869
               V       S  +        QQ      G++ P    P Q   P+   +        
Sbjct: 994  PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP----PPQPAKPQQVIQHHHSPRHH 1049

Query: 870  --------SLLEKPSELMSHS---SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 918
                     L E PS LM HS   S F SLT  S  Q+             + L ++S  
Sbjct: 1050 KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK-------QELRAASVV 1102

Query: 919  ELSPSMAPQETSLYS-LFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP---PTHN 974
            +  P +  +E  ++S +    P+SPSL        P         P  LP  P   P   
Sbjct: 1103 QPQPLVVVKEEKIHSPIIRSEPFSPSL-----RPEPPKHPESIKAPVHLPQRPEMKPVDV 1157

Query: 975  HNSV---PFSNFGPIGTPD 990
               V   P  N  P G PD
Sbjct: 1158 GRPVIRPPEQNAPPPGAPD 1176


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
            sapiens]
          Length = 2191

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 130/536 (24%), Positives = 191/536 (35%), Gaps = 88/536 (16%)

Query: 607  GAFPPLPSRPGFPPPTYVIPPPVAFSMGS---GYTFPAGVSVPGTF-LQPTAHSPAGNQV 662
            G++P   S P  PPP    P   A + G+   G    AG+ +      Q  A SPA    
Sbjct: 377  GSYPEYSS-PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAA 435

Query: 663  QAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQP-LTSLPAQPTAQSTSQLQVQAL 718
            Q  ++SH   S   P  PGP    +QG        ++P L  + + P +Q          
Sbjct: 436  Q--QRSHPAMS---PGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490

Query: 719  TQQQQSPTK-AVPALGKSPPHHSGFQQYQQADASKQLWN------PPQV--QGPLGKIMP 769
            +     P +  +   G++P   +G Q  QQ D+    W       PPQ   QG  G    
Sbjct: 491  SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550

Query: 770  VKQPYYLQTQDPIKL-----FEPS-----LQPPV-MQQQPLEKKMKPFPMEPYNHNPSEV 818
             +QPYY Q   P  L     + PS      QP   M Q+    + +P P+ P   N  ++
Sbjct: 551  GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP-PLAPGKPNHEDL 609

Query: 819  KV-----PEFYWDSSYSMAD---------NRSVMAQQANIDRRGKRSP--GVFRPEQDP- 861
             +     P    D S S+ D         + +V A  +   +  + +P    F P   P 
Sbjct: 610  NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669

Query: 862  ---VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 918
               +P  P        PS + S   S  S +G  ++    P + M  +  G    SSS  
Sbjct: 670  LSSIPGGP-------SPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHP 721

Query: 919  ELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV 978
             LS S  PQE    +   GT  +P +       T  S SPH S P     +  +    S 
Sbjct: 722  ALSQSPMPQERGFMA---GTQRNPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSN 777

Query: 979  PFSNFGP----IGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1034
                +GP     G   N  R          PA  G     + + S S        + +  
Sbjct: 778  SSGTYGPQMSQYGPQGNYSR---------PPAYSG-----VPSASYSGPGPGMGISANNQ 823

Query: 1035 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP 1090
              G GPS +   AV +  + S  +     P P  +  +        Q+G   M PP
Sbjct: 824  MHGQGPS-QPCGAVPLGRMPS--AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 876



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 80/319 (25%), Positives = 115/319 (36%), Gaps = 37/319 (11%)

Query: 439 GHQGITGD-KEGQQRRIRQQ----RLISIGKWIADNQPRLIQCENEVGKLLFITEI-PEL 492
           G QG++G  ++GQQ    QQ     L    +++     +  Q + ++ +  + T   P L
Sbjct: 540 GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPL 599

Query: 493 ILEDPSEAKENLILQE--------TSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV 544
               P+    NLI QE        +  I+ L       L S +S S + S+  D      
Sbjct: 600 APGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQ 659

Query: 545 VTFKENIKTREVNRDQGRSFPPKEVKS---QTELRKTPVSEARKTPVTQTPTQASNSQFI 601
             F  +      +   G S  P  V S     + R  P+S A   P +Q P Q   SQ  
Sbjct: 660 SPFSPHASPHLSSIPGGPS--PSPVGSPVGSNQSRSGPISPA-SIPGSQMPPQPPGSQSE 716

Query: 602 PIHHPG-AFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 660
              HP  +  P+P   GF   T   P    +          G    G  + P  H   G 
Sbjct: 717 SSSHPALSQSPMPQERGFMAGTQRNPQMAQY----------GPQQTGPSMSP--HPSPGG 764

Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQ--QSQPPSQQPLTSLP-AQPTAQSTSQLQVQA 717
           Q+ AG  S    +     GP     GPQ   S+PP+   + S   + P          Q 
Sbjct: 765 QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824

Query: 718 LTQQQQSPTKAVPALGKSP 736
             Q    P  AVP LG+ P
Sbjct: 825 HGQGPSQPCGAVP-LGRMP 842



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 39/225 (17%)

Query: 604  HHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 663
            H PG +P  P+        Y   PP     G  Y           + Q        ++  
Sbjct: 1303 HQPGLYPQQPNYKRHMDGMY--GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP 1360

Query: 664  AGKQSHIPYSQQRPSGPGPMNQ---GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720
               Q   PYS++R  GPG +      PQ    P Q   +  P Q    + + +      +
Sbjct: 1361 IQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNR 1420

Query: 721  Q-QQSPTKAVPALGKS------------------PPHHSGFQQYQQADASKQ-LWNPPQV 760
            Q    PT+A P  G +                  P H S  Q Y  + AS Q +  PP  
Sbjct: 1421 QGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPP-- 1478

Query: 761  QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805
                       QP Y QT   +         P   Q+ LE +M P
Sbjct: 1479 -----------QPSY-QTPPSLPNHISRAPSPASFQRSLENRMSP 1511


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 119/459 (25%), Positives = 169/459 (36%), Gaps = 86/459 (18%)

Query: 571 SQTELRKTPVSEARKTPVTQT-PTQASNSQFIPIHHPGAFPP-----LPSRPGFPP---- 620
           S T+ R  P  +   TP+  T P     +  +P+  P    P     LPS P  PP    
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369

Query: 621 PTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP----AGNQVQAGKQSHIPYSQQR 676
           P+   PP  A    S  T P  + VP +   P+  +P    A + +QA      P  Q  
Sbjct: 370 PSMTTPPMQA--PPSLQTIPP-IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426

Query: 677 PSGPGPMNQGPQQSQ----------------PPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720
            S    +   P+Q+Q                PP Q PL SLPA P  Q++    V  L+ 
Sbjct: 427 HSF---LTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPASPPLQTSLSPAVSPLSS 482

Query: 721 QQQ-SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQ 779
                P +A+ +L    P         QA  S  +  P + Q  L        P  L T 
Sbjct: 483 PLTIHPLQALSSLASHSP---------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533

Query: 780 DPIKLFEPSLQPPVMQQQP-------LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMA 832
               L  PSL PP +Q          LE    P P  P    PS +  P     SS +  
Sbjct: 534 PLENL--PSLAPPPLQTASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIATP 590

Query: 833 DNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFS 892
             ++  A  A+   +G  SP +  P   P P+ P   +L   P +      +   L+  +
Sbjct: 591 PPQAPPAL-ASPPLQGLPSPPL-SPLATPPPQAPPXLAL--PPLQAPPSPPASPPLSPLA 646

Query: 893 LNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHST 952
               + PN    + +         +A  SP  +P   + +S        P+ P  S  +T
Sbjct: 647 TPSPQAPNALAVHLL---------QAPFSPPPSPPVQAPFS-------PPASPPVSPSAT 690

Query: 953 PASQSPHS--SNPSSLPSSPPTHNHNSVPFSNFGPIGTP 989
           P SQ+P S  + P  +P SPP     S P S   P  TP
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPA----SPPMS---PSATP 722



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 83/378 (21%), Positives = 127/378 (33%), Gaps = 61/378 (16%)

Query: 628 PVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGP 687
           P   ++ +G         PGT     A        + G     P ++ RP   GP     
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210

Query: 688 QQSQPPSQQPLTSLPAQPTA----QSTSQLQVQALTQQQQSPTKAVPALGKSP--PHHSG 741
             S+  + +P  +   +P+A    Q  +   + +      SP ++ P+   +P  P H  
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270

Query: 742 FQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY---LQTQDPIKLFEPSLQPPVMQQQP 798
               Q      Q   PPQV  P     P   P     L T  P       + PP     P
Sbjct: 271 ----QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326

Query: 799 LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPE 858
           L   + P P       P    +P              +  +  A    +   SP    P 
Sbjct: 327 LPATLPPSP-------PLATPLP-------------LAPPSPSAPPSLQTLPSPPATPPS 366

Query: 859 QDP----VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 914
           Q P     P M    SL   P   + HS +  SL       +  P+    + +       
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-------QAPPSPLALSSLQATTSLG 419

Query: 915 SSKAELSPS---MAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPP 971
           S   + + S   M+P++T      + +  SPS PAS+   +P  Q+     P SLP+SPP
Sbjct: 420 SPTLQATHSFLTMSPRQT------QASLTSPSRPASTPPDSPPLQA-----PLSLPASPP 468

Query: 972 THNHNSVPFSNFGPIGTP 989
                S   S   P+ +P
Sbjct: 469 LQTSLSPAVS---PLSSP 483



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 65/245 (26%), Positives = 86/245 (35%), Gaps = 39/245 (15%)

Query: 577 KTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPP------PVA 630
           +TP S A  TP  Q P   ++     +  P    PL + P   PP   +PP      P A
Sbjct: 582 ETPSSIA--TPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQAPPSPPA 638

Query: 631 FSMGSGYTFP---AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQR-----PSGPGP 682
               S    P   A  ++    LQ     P    VQA      P+S        PS   P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA------PFSPPASPPVSPSATPP 692

Query: 683 MNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGF 742
               P  + PP Q P  S PA P    ++    QA       P +  P+   SPP     
Sbjct: 693 SQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP----- 746

Query: 743 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIK-LFEPSLQ-PPVMQQQPLE 800
                   S     PP+V  PL    P++ P       P+  L +P  Q PP +   PL+
Sbjct: 747 -------MSPSATPPPRVP-PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 801 KKMKP 805
               P
Sbjct: 799 ALPSP 803



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 36/142 (25%), Positives = 47/142 (33%), Gaps = 11/142 (7%)

Query: 579 PVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP--------PPTYVIPPPVA 630
           P+S +   P    P  A+    +P   P + P  PS    P        PP  V P P A
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774

Query: 631 FSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQS 690
               S    P   + P     P    P+     A      P+S        P+   P Q+
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQA 831

Query: 691 QPPSQQPLTSLPAQPTAQSTSQ 712
            P    PL  +P  P A  T Q
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQ 853


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)

Query: 557 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615
           NR    S P P++ +S ++          + P  Q PT  + +   P   P   P LP+ 
Sbjct: 154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 209

Query: 616 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675
           PG  P    +PP      GS    P     P     PTA  P    +Q     H     Q
Sbjct: 210 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 255

Query: 676 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735
           RP  P P    P  S  P  QPLT    QP+A S +Q                 P  G+ 
Sbjct: 256 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 296

Query: 736 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789
           PP     Q     Q     +    PPQ    Q PLG       P+   T   +   + +L
Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 353

Query: 790 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849
           Q    QQ P E+ + P P+                                         
Sbjct: 354 QS---QQPPREQPLPPAPLA---------------------------------------- 370

Query: 850 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909
             P +  P   P+P++P  ++          H       + FS+N    P  ++      
Sbjct: 371 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 415

Query: 910 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969
           K L+S S     PS  P    L    +  P SP+ P     S      P S  P+ L   
Sbjct: 416 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474

Query: 970 PPTHNHNSVPFSNFGP 985
            P       PF   GP
Sbjct: 475 APQPPFAQHPFVPGGP 490


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)

Query: 557  NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615
            NR    S P P++ +S ++          + P  Q PT  + +   P   P   P LP+ 
Sbjct: 708  NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763

Query: 616  PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675
            PG  P    +PP      GS    P     P     PTA  P    +Q     H     Q
Sbjct: 764  PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809

Query: 676  RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735
            RP  P P    P  S  P  QPLT    QP+A S +Q                 P  G+ 
Sbjct: 810  RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850

Query: 736  PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789
            PP     Q     Q     +    PPQ    Q PLG       P+   T   +   + +L
Sbjct: 851  PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907

Query: 790  QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849
            Q    QQ P E+ + P P+                                         
Sbjct: 908  QS---QQPPREQPLPPAPLA---------------------------------------- 924

Query: 850  RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909
              P +  P   P+P++P  ++          H       + FS+N    P  ++      
Sbjct: 925  -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969

Query: 910  KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969
            K L+S S     PS  P    L    +  P SP+ P     S      P S  P+ L   
Sbjct: 970  KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028

Query: 970  PPTHNHNSVPFSNFGP 985
             P       PF   GP
Sbjct: 1029 APQPPFAQHPFVPGGP 1044


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)

Query: 557  NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615
            NR    S P P++ +S ++          + P  Q PT  + +   P   P   P LP+ 
Sbjct: 708  NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763

Query: 616  PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 675
            PG  P    +PP      GS    P     P     PTA  P    +Q     H     Q
Sbjct: 764  PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809

Query: 676  RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 735
            RP  P P    P  S  P  QPLT    QP+A S +Q                 P  G+ 
Sbjct: 810  RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850

Query: 736  PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 789
            PP     Q     Q     +    PPQ    Q PLG       P+   T   +   + +L
Sbjct: 851  PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907

Query: 790  QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 849
            Q    QQ P E+ + P P+                                         
Sbjct: 908  QS---QQPPREQPLPPAPLA---------------------------------------- 924

Query: 850  RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 909
              P +  P   P+P++P  ++          H       + FS+N    P  ++      
Sbjct: 925  -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969

Query: 910  KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 969
            K L+S S     PS  P    L    +  P SP+ P     S      P S  P+ L   
Sbjct: 970  KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028

Query: 970  PPTHNHNSVPFSNFGP 985
             P       PF   GP
Sbjct: 1029 APQPPFAQHPFVPGGP 1044


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 14/188 (7%)

Query: 657 PAGNQVQAGKQSHI-PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 715
           P   Q Q  +Q+H   +SQQ+   P      PQQ   P QQ           Q   QLQ 
Sbjct: 447 PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506

Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY 775
             L QQQ         L +    HS  QQ QQ    +Q       Q    ++     P+ 
Sbjct: 507 HQLQQQQ---------LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557

Query: 776 LQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE--FYWDSSYSMAD 833
            QT   ++   P  QPP  QQQ  +    P   + + H+P+ V++PE  F     +++AD
Sbjct: 558 SQTSQALQHQVPPQQPP-QQQQQQQPPPSPQQHQLFGHDPA-VEIPEEGFLLGCVFAIAD 615

Query: 834 NRSVMAQQ 841
               M+ +
Sbjct: 616 YPEQMSDK 623



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 46/154 (29%), Positives = 65/154 (42%), Gaps = 24/154 (15%)

Query: 653 TAHSPAGN---QVQAGKQSH-----IPYSQQRPSGPGPMNQGPQQSQPPSQQ-PLTSLPA 703
           T  +P  N   QV   +Q H     + +SQ + +    M Q  QQ+Q   QQ P+  L  
Sbjct: 362 TLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP 421

Query: 704 QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGP 763
           Q         Q+  L QQQQ      P   + PPH    QQ QQ  A    ++  Q+Q P
Sbjct: 422 Q---------QIMQLQQQQQQQISQQP-YPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP 471

Query: 764 LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 797
             ++ P +Q +  Q Q      +P  Q   +QQQ
Sbjct: 472 QQQLHPPQQLHRPQQQ-----LQPFQQQHALQQQ 500



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 50/291 (17%), Positives = 91/291 (31%), Gaps = 27/291 (9%)

Query: 689 QSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT------KAVPALGKSPPHHSGF 742
           QS   S+   T  PA  T ++ +     A  QQ   P+      + + A  K+       
Sbjct: 320 QSSERSEMIATWSPAVRTLRNITN---NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNH 376

Query: 743 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 802
            Q    +A+  L++  +V      +   +Q    Q Q P+   +P     + QQQ  +  
Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQIS 436

Query: 803 MKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPV 862
            +P+P +P +        P          A       QQ    ++    P      Q  +
Sbjct: 437 QQPYPQQPPH--------PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL 488

Query: 863 PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP 922
                + +L ++  +L  H           L Q++       + +  +      + +   
Sbjct: 489 QPFQQQHALQQQFHQLQQH----------QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538

Query: 923 SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTH 973
            M  Q+       +  P       +  H  P  Q P        P SP  H
Sbjct: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH 589


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 59/217 (27%), Positives = 72/217 (33%), Gaps = 32/217 (14%)

Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 665
           P+   P  PPP ++ PPP   + G     P G   P    Q    +P G+ V       G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 666 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 722
                P     P  P P  Q P       PP QQ     P  P   S+         QQ 
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528

Query: 723 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 782
            + T      G  PP    +QQ Q A A+      PQ+QG      P   P     Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577

Query: 783 KLFEPSLQPPVMQQQPLEKKM-------KPFPMEPYN 812
               P   PP     P    M        P PM+P N
Sbjct: 578 ---PPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN 611



 Score = 33.9 bits (76), Expect = 0.86
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 6/49 (12%)

Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFP 640
           P    N   +P+  PG  PPLP  PG PPP    PPP   S G  Y  P
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAGMMYAPP 600


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 108/471 (22%), Positives = 151/471 (32%), Gaps = 87/471 (18%)

Query: 591  TPTQASN-SQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPA-GVSVP 646
            +P+ AS+ S F P + P A+ P P  PG P P+  Y+  P  A S     T PA     P
Sbjct: 1547 SPSAASDASGFSPGYSP-AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSP 1605

Query: 647  GTFL-QPTAHSPAGNQVQAGKQSHIPYS-QQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQ 704
            G +  Q  ++SP          S+ P S    P+ P      P  S        TS    
Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665

Query: 705  PTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPL 764
            PT+ S S       T    SPT        SP +      Y     S    +P     P 
Sbjct: 1666 PTSPSYSP------TSPSYSPT--------SPSYSPTSPSYSPTSPSYSPTSPS--YSPT 1709

Query: 765  GKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFY 824
                    P Y  T        PS  P      P      P      N+ P+        
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSP---TSPNYTPT-------- 1758

Query: 825  WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 884
               SYS                    SP       +  P  P        PS   +  S 
Sbjct: 1759 -SPSYS------------------PTSPSYSPTSPNYTPTSPNYSP--TSPSYSPTSPSY 1797

Query: 885  FLSLTGFSLNQERY-PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPS 943
              +   +S +  RY P +  +        +S S +  SPS +P           TP SPS
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTP------SSPSYSPSSPSYSPTSPKY------TPTSPS 1845

Query: 944  LPASSDHSTPASQSPHSSNPSSLPSSP-------------PTHNHNSVPFSNFGPIGTPD 990
               SS   TP S     ++P   P+SP             P ++  S  +S   P+ TP 
Sbjct: 1846 YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTP- 1904

Query: 991  NRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPS 1041
                 T+ ++    P        Y   + +   +  + ST S T  G+ P+
Sbjct: 1905 -----TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 110/536 (20%), Positives = 167/536 (31%), Gaps = 48/536 (8%)

Query: 526  VLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARK 585
            +++ +R+  N  DTG     +F+E +         G S P K V     L +   +    
Sbjct: 1411 LMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGC 1470

Query: 586  TPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGF---PPPTYVIPPPVA-FSMGSGYTFPA 641
              +     +      IP + PG     P+   F   P P   I P +  ++ G+   + A
Sbjct: 1471 FDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGA 1530

Query: 642  GVSVPGTFLQPTA--HSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPL 698
                 G+ + P A   SP+     +G    + P     P  PG  + GP     PS    
Sbjct: 1531 WSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPG--SPGPSSPYIPSPGGA 1588

Query: 699  TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQ-QYQQADASKQLWNP 757
             S    PT+ +         T Q  S +   P+   + P +S     Y     S    +P
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSP 1648

Query: 758  PQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSE 817
                 P         P Y  T        PS  P      P      P        +PS 
Sbjct: 1649 SY--SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706

Query: 818  VKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 877
                  Y  +S S +      +  +        S     P   P             P+ 
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPT-----------SPNY 1755

Query: 878  LMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEG 937
              +  S   +   +S     Y              TS + +  SPS +P   S       
Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTP------------TSPNYSPTSPSYSPTSPSY------ 1797

Query: 938  TPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP------PTHNHNSVPFSNFGPIGTPDN 991
            +P SPS   SS   TP S +   S+PS  PSSP      P +   S  +S   P  TP +
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS 1857

Query: 992  -RDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSS 1046
             +   T+ ++    P        Y   T     +    S  S  +T   P    +S
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTS 1913


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 109/481 (22%), Positives = 182/481 (37%), Gaps = 84/481 (17%)

Query: 496  DPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTRE 555
            D ++ +E++  +   +    A DG PG      T   L ++    + P            
Sbjct: 1068 DENDLEEDVDSEPAEIEGEAAEDGDPG-----DTGAELDDDQHWSDSPS----------- 1111

Query: 556  VNRDQGRSFP-PKEVKSQTELR------KTPVSE-------ARKTPVTQTPTQASNSQFI 601
             + D+    P P E +++ ELR      K P S        ++ T   ++P Q S   FI
Sbjct: 1112 -DADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSP-QESALLFI 1169

Query: 602  PIHHPGA----FPPLPSRPGFPPPTY-VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 656
            P+H P       PP+P+      P   + P P+          P+ +           HS
Sbjct: 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKA--------VHS 1221

Query: 657  PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 716
            P  +Q     ++  P S   P  P P       + PPS  P+ S P QP+ ++T      
Sbjct: 1222 PIRSQPVTLPEARTPVS---PGSPQPQPPVAASTPPPSPLPICSQP-QPSTEAT------ 1271

Query: 717  ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 776
             +    QSP +  PA  K+    +      Q+D   +L +P  V   L +   V++ +++
Sbjct: 1272 -VPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEE-FWM 1329

Query: 777  QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 836
            ++ +  +          +   P+++   P P  P    P+   V    +    S  D   
Sbjct: 1330 KSAEIRR---------SLGLTPVDRSKGPEPSFP---TPAFRPVSLKSYSVEKSPQDEGL 1377

Query: 837  VMAQQANIDRRGKRSPGVFRPEQDPV----PRMPFEKSLLEKPSELMS-HSSSFLSLTGF 891
             + +  +I +R     G+ +PE +P+    PR P ++ L     E     SSS L L G 
Sbjct: 1378 HLLKPLSIPKR----LGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGS 1433

Query: 892  SLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSL-YSLFEGTPWS----PSLPA 946
            S N +   + S FN      LT  S     P    +  +L   L E  P +    P LPA
Sbjct: 1434 SSNMKTLGSQS-FNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPA 1492

Query: 947  S 947
            +
Sbjct: 1493 T 1493


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 52/190 (27%), Positives = 64/190 (33%), Gaps = 22/190 (11%)

Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 665
           P+   P  PPP ++ PPP   + G     P G   P    Q    +P G+ V       G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 666 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 722
                P     P  P P  Q P       PP QQ     P  P   S+         QQ 
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528

Query: 723 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 782
            + T      G  PP    +QQ Q A A+      PQ+QG      P   P     Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577

Query: 783 KLFEPSLQPP 792
               P   PP
Sbjct: 578 PPGAPPPPPP 587



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 6/43 (13%)

Query: 592 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMG 634
           P    N   +P+  PG  PPLP  PG PPP    PPP   S G
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAG 594


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 88/366 (24%), Positives = 125/366 (34%), Gaps = 57/366 (15%)

Query: 463 GKWIADNQPRLIQCENEVGKLLFI----TEIPELILEDPSEAKENLILQETSVIESLAAD 518
           GK I  N+        +VG  +FI     EI E +L D   A   +ILQ   ++      
Sbjct: 81  GKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAF-GVILQTPKIMRDPDTG 139

Query: 519 GSPGLKSVLSTSRNLSNN----------CDTGEKPVVTFKENIKTREVNRDQGRSFPPKE 568
            S G   +   S + S+           C+        FK++ K         R    + 
Sbjct: 140 NSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQN 199

Query: 569 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIP---IHHPGAFPPLPSRPGFPPPTY-- 623
             SQ +      ++A   P    P  +S    +P   +  PG+FPP    PG  PP    
Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP 259

Query: 624 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS-----PAGNQVQAGKQSHIPYSQQRPS 678
            +PPP      +G+  P     PG       HS     P G     G  S +  +   P 
Sbjct: 260 AMPPPPMPPGAAGHG-PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPG-MSQMQLAHHGPH 317

Query: 679 GPGPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-- 734
           G G  + GP  S  QPP + P    P  P                   P   +P  G   
Sbjct: 318 GLGHPHAGPPGSGGQPPPRPP----PGMP---------------HPGPPPMGMPPRGPPF 358

Query: 735 -SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPV 793
            SP  H G            +  PP +  P G   P + P Y   + P+    P+ +PPV
Sbjct: 359 GSPMGHPGPMP------PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV 412

Query: 794 MQQQPL 799
             + PL
Sbjct: 413 PPRGPL 418


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 89/384 (23%), Positives = 134/384 (34%), Gaps = 46/384 (11%)

Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685
           PPP    M          + P T LQ      A  Q Q  +Q    + QQ+ +      Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182

Query: 686 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 745
             QQ Q  +QQ       Q   Q   QLQ Q   QQQQ   K          HH   QQ 
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231

Query: 746 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805
           QQ    +QL    Q+Q  L +    +Q    Q Q  ++   P  QPP+ Q QP   +  P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287

Query: 806 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 861
             ++  +H       P+        +A N+       +Q   +  + +  PG     Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344

Query: 862 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSM-----FNEV 907
                    V + P +  + ++ + + +  ++ +   G  +  E      M     F   
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404

Query: 908 YGKNLTSSSKAEL--SPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSS 965
              +   SS   L   P     ++SL  L   +P    +        P   SP    PSS
Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP-GQQVQTPQSMPPPPQPSPQPGQPSS 463

Query: 966 LPSSPPTHNHNSVPFSNFGPIGTP 989
            P+S  +      P S+F P  +P
Sbjct: 464 QPNSNVSSGPAPSP-SSFLPSPSP 486



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 47/166 (28%), Positives = 63/166 (37%), Gaps = 6/166 (3%)

Query: 641 AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP-GPMNQGPQQS-QPP---SQ 695
           A VS P   LQ     PA      G     P       G  G M Q    S QPP   S 
Sbjct: 76  ASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSG 135

Query: 696 QPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLW 755
               S+    TA   +QLQ+Q +  QQQ   +      ++       QQ QQ   ++Q  
Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSA 195

Query: 756 NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEK 801
              Q Q  + +   ++Q    Q Q  IKL   + Q    QQQ L++
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQ-QQQHLIKLHHQNQQQIQQQQQQLQR 240



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 15/143 (10%)

Query: 652 PTAHSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 710
           P++  P G Q  A   QS +P      S P P     QQ Q P   P    P+    Q +
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPML----SSPSP----GQQVQTPQSMPPPPQPSPQPGQPS 462

Query: 711 SQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQVQGPL 764
           SQ      +    SP+  +P+    P   P  +   Q     +   L    NP  V  P 
Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522

Query: 765 GKIMPVKQPYYLQTQDPIKLFEP 787
           G     +Q Y  + +   K  EP
Sbjct: 523 GSSQAEEQQYLDKLKQLSKYIEP 545


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 58/205 (28%), Positives = 76/205 (37%), Gaps = 30/205 (14%)

Query: 566 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 625
           P+ + S T   + P S+A        PTQ    Q  P+      PP    P  P P    
Sbjct: 505 PQRLPSPTSAPQQPASQAAP------PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA 558

Query: 626 PPPVAFSMGS---------GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYS--- 673
            PP A    S             P G    G   +P    PAG   QA +   +P +   
Sbjct: 559 GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP--GPAGPTRQASQAGPVPRTGPP 616

Query: 674 ---QQRPSGPGPMNQ-GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAV 729
              Q RPSGPGP  +  PQ +Q PSQ     +P   TA +      Q    + QS T A 
Sbjct: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAAGGPPHPQ--LNKSQSLTNAF 670

Query: 730 PALGKSPPHHSGFQQYQQADASKQL 754
                +PP  S  Q   +A+  + L
Sbjct: 671 NLPEPAPPRPSLSQDEVKAETIRSL 695



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 56/186 (30%), Positives = 67/186 (36%), Gaps = 37/186 (19%)

Query: 611 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670
           P P R G  PP    PPP      SG   PAG  +P     PT+ +P     QA   +  
Sbjct: 472 PGPQRQG--PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS-APQQPASQAAPPTQG 528

Query: 671 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730
              Q RP   GP         PP+ +P    PA P+ Q   Q      T+Q      A P
Sbjct: 529 QGRQSRPVAGGP-------GAPPAARP----PASPSPQ--RQAGPPQATRQTSVSGPAPP 575

Query: 731 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQ 790
               +PP   G QQ Q          PP  Q P G   P +Q        P+    P   
Sbjct: 576 KASGAPP---GGQQRQ---------GPP--QKPPGPAGPTRQ---ASQAGPV----PRTG 614

Query: 791 PPVMQQ 796
           PP  QQ
Sbjct: 615 PPTTQQ 620



 Score = 38.5 bits (88), Expect = 0.035
 Identities = 48/192 (25%), Positives = 64/192 (33%), Gaps = 37/192 (19%)

Query: 663 QAGKQSHIPYSQQRPS--------GPGPMNQGPQQSQ--------------PPSQQPL-- 698
           Q  +Q   P +QQRP         GPGP  QGP   Q              PP+  PL  
Sbjct: 447 QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506

Query: 699 -----TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 753
                TS P QP +Q+    Q Q    +  +     P   + P   S  +Q     A++Q
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566

Query: 754 LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ---PLEKKMKPFPMEP 810
                 V GP         P   Q Q P +   P    P  Q     P+ +   P   +P
Sbjct: 567 ----TSVSGPAPPKASGAPPGGQQRQGPPQK-PPGPAGPTRQASQAGPVPRTGPPTTQQP 621

Query: 811 YNHNPSEVKVPE 822
               P     P+
Sbjct: 622 RPSGPGPAGRPK 633


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 75/327 (22%), Positives = 121/327 (37%), Gaps = 43/327 (13%)

Query: 611  PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670
            P+P +PG P     + PP        ++ PA        +Q      AG Q +AG     
Sbjct: 2099 PIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA--------MQNMNPMQAGVQ-RAGLPQQQ 2149

Query: 671  PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 730
            P  Q +P   G   Q  Q +   +  P         +Q    L+ Q + QQQQ    A P
Sbjct: 2150 PQQQLQPPMGGMSPQAQQMNMNHNTMP---------SQFRDILRRQQMMQQQQQQG-AGP 2199

Query: 731  ALGKSPPHHSGFQQYQ------QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKL 784
             +G    +H+ FQQ Q      Q     Q       QG +G+I  + Q    +    ++ 
Sbjct: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259

Query: 785  FEPSLQPPVMQQQPLEKKMKPFPMEPYNHN-PSEVKVPEFYWDSSYSMADNRSVMAQQAN 843
            ++  L      QQ +   ++P PM P  H  P++ + P        +   N+ V + Q  
Sbjct: 2260 YQQRL-----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ-VRSPQPV 2313

Query: 844  IDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN--- 900
               R +  P    P   P PRM  + S      +  S     ++     + Q  + +   
Sbjct: 2314 PSPRPQSQP----PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQ 2369

Query: 901  NSMFNEVYGK----NLTSSSKAELSPS 923
            NSM +++       NL  +S  +L  S
Sbjct: 2370 NSMLSQLASNPGMANLHGASATDLGLS 2396



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 77/331 (23%)

Query: 577  KTPVSEARKTPVT---QTPTQASNSQFIPIH---------HPGAFPPLPSRPGFPPPTYV 624
            + PVS+A+ +  +    +P     SQ   IH         H  +  P+PSR   P  T  
Sbjct: 788  QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT-- 845

Query: 625  IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 684
             PP +        T PA V  P          PA   +  G QS   +   R +   P  
Sbjct: 846  -PPSIGAQQPPATTIPAPVPTP----------PA---MPPGPQSQALHPPPRQTPTPPTT 891

Query: 685  QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ 744
            Q PQQ QP       SLPA   A S  Q Q Q  +QQ  + +   P     PP  +    
Sbjct: 892  QLPQQVQP-------SLPA---APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941

Query: 745  YQQADASKQLWNPPQVQGP--LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 802
                    Q+ NPP         + +  KQP                     Q+  +E K
Sbjct: 942  QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP--------------------SQEVKMEAK 981

Query: 803  MKPFPMEPYNHNP---SEVKVPEFYWDSSYS-------------MADNRSVMAQQANIDR 846
            M+    EP +  P   SE KV +   +S+ +               D  S  A Q++   
Sbjct: 982  MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSS-PA 1040

Query: 847  RGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 877
             G+    +F+PE+     MP  ++L  +  E
Sbjct: 1041 PGQSKKKIFKPEELRQALMPTLEALYRQDPE 1071



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 22/154 (14%)

Query: 663  QAGKQSHIPYSQQRPSGPGPMN-QGPQQSQPPSQQPLTSLP--------AQPTAQSTSQL 713
            Q G  S  P +   P+G  P   Q PQ +  P   P  S+P        A P +Q  +  
Sbjct: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903

Query: 714  QVQALTQQQQSPTKAVPALGKSPPH--HSGFQQYQQADASKQLWNPPQVQGPLGKIMPVK 771
            QV   T     P  A P L   PP       Q  + A+  +Q+ +    Q P+   MP  
Sbjct: 1904 QVTPPTP----PQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959

Query: 772  QPYYLQ-------TQDPIKLFEPSLQPPVMQQQP 798
             P           T+ P    EP + P  MQQQP
Sbjct: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 76/355 (21%), Positives = 116/355 (32%), Gaps = 82/355 (23%)

Query: 435  DFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELIL 494
            D S   Q       G  RR+  QR I        +     QC N    L           
Sbjct: 1714 DESNNQQAAATQSPGDSRRLSIQRCIQ-------SLVHACQCRNANCSL----------- 1755

Query: 495  EDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV---VTFKENI 551
              PS  K   ++Q T   +     G P  K +++     + +C   + PV   +  K+ +
Sbjct: 1756 --PSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKL 1813

Query: 552  KTREV-NRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 610
            + +++ +R Q      + + S          +   +P   TPT  +  Q           
Sbjct: 1814 RQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQ----------- 1862

Query: 611  PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 670
              P+ P  P PT    P                        P +  P   + QA      
Sbjct: 1863 --PTTPQTPQPTSQPQPT----------------------PPNSMPPYLPRTQAAG---- 1894

Query: 671  PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ--ALTQQQQSPTKA 728
            P SQ + +G       PQ +QPP       LP  P A     +Q+Q  A TQ+Q +  + 
Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPP-------LPGPPPAAVEMAMQIQRAAETQRQMAHVQI 1947

Query: 729  V--PALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 781
               P   + PP            A   +  PP  +GP G + P   P  +Q Q P
Sbjct: 1948 FQRPIQHQMPP--------MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP 1994



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 18/168 (10%)

Query: 667 QSHIPYSQQRPSGPGPMNQGPQQSQPPSQ---QPLTSLPAQ-------PTAQSTSQLQV- 715
           Q H   +Q     P PM  GP+  QP +Q    P T  P+Q       P A S+ Q  V 
Sbjct: 734 QHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792

Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMP----VK 771
           QA       P  +      S   H    Q  Q    +   +P   + P     P     +
Sbjct: 793 QAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQ 852

Query: 772 QPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVK 819
           QP    T  P  +  P   PP  Q Q L    +  P  P    P +V+
Sbjct: 853 QP--PATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQ 898



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 35/117 (29%), Positives = 43/117 (36%), Gaps = 12/117 (10%)

Query: 658 AGNQVQAGKQSHIPY--SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 715
           AGN +    Q   P    Q    GP P+  G   +  P   P T  P Q    S   LQ+
Sbjct: 215 AGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQI 274

Query: 716 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQ 772
           Q  T+   S   +  A+ K      G     Q  A       PQVQ P G + PV Q
Sbjct: 275 Q--TKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA-------PQVQQP-GLVTPVAQ 321


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 19/119 (15%)

Query: 587 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVP 646
           P  QTP +       P+  PG  PP P  PG PPP  V+PPP+A     G   P  V  P
Sbjct: 231 PAGQTPPRP------PLGPPG--PPGP--PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280

Query: 647 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 705
           G   QP    P G  +  G    +P     P GP P    PQQ  PP   P    P  P
Sbjct: 281 G---QPFGQPPLG-PLPPGPPPPVP-GYGPPPGPPP----PQQGPPPPPGPFPPRPPGP 330



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 34/138 (24%), Positives = 43/138 (31%), Gaps = 11/138 (7%)

Query: 566 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 625
           P +   Q  L   P       P    P      Q  P   PG FPP P  P  PP T   
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339

Query: 626 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 685
           PP +          P G   P   + P    P  N       S  P        P P ++
Sbjct: 340 PPHLPGP-------PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392

Query: 686 G----PQQSQPPSQQPLT 699
           G    P +    ++ PL+
Sbjct: 393 GDYGPPGREMDTARTPLS 410


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 77/343 (22%), Positives = 126/343 (36%), Gaps = 67/343 (19%)

Query: 664 AGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQ 723
           + +Q      QQ+        Q  QQ Q PS QP  SLP+QP  +S   LQ + L QQ Q
Sbjct: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696

Query: 724 SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPY----YLQTQ 779
           +           P    G+Q  QQ     Q     Q  GP     P   P     Y+ +Q
Sbjct: 697 N----------QPIAGMGYQVSQQ-QRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745

Query: 780 DPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMA 839
             +   +   +   +Q+Q +E+K +    +                     M  +   +A
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQ--------------------QMLADAEKIA 785

Query: 840 QQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYP 899
            Q  I+R   R P  ++ ++  V  M        +P+   S  SS +SL           
Sbjct: 786 PQDQINRHLSRPPPDYKDQRRNVGNM--------QPTAQYSGGSSTISLNS--------- 828

Query: 900 NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDH----STPAS 955
           N ++ N V    + + + + LS S   +  SL +  +      +LP +  +    ++  +
Sbjct: 829 NQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMN 888

Query: 956 QSPHSSNPSSLPSS--------PPT---HNHNSVPFSNFGPIG 987
           Q     NP  L ++        PPT    N+N+V     G +G
Sbjct: 889 QLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVG 931



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 73/355 (20%), Positives = 120/355 (33%), Gaps = 62/355 (17%)

Query: 497 PSEAKENLILQ-ETSVIESLAADGSPGLKSVLS-TSRNLSNNCDTGEKPVVTFKENIKTR 554
           PS   E ++++ E S   +    GSP L+   +  + +++N+  +   P+ +  ++    
Sbjct: 355 PSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQP 414

Query: 555 EVNRDQGRSFPP-KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLP 613
           +      R+ P  +EV    +L++   +  +   + Q   Q         H P  +  LP
Sbjct: 415 QTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ---------HQPTNWSALP 465

Query: 614 SRPGFPPPTY---VIPPPV--------------AFSMGSG-------YTFPAGVSVPGTF 649
           S  G  P  +    IP P                 + GSG       Y + AG S  G  
Sbjct: 466 SSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGH 525

Query: 650 LQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQPLTSLPA--- 703
           L         +  ++   +  P  + R     P+   N      Q PS  P  + P+   
Sbjct: 526 LDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLH 585

Query: 704 ---QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 760
              Q   Q   Q Q Q   QQQQ                   QQ QQ    +Q     Q 
Sbjct: 586 YTQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQSSISAQQ 628

Query: 761 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 815
           Q      +  +Q    Q Q   +  +   Q    QQQP  +  +  P +P   +P
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 128/544 (23%), Positives = 183/544 (33%), Gaps = 91/544 (16%)

Query: 601  IPIHHP-GAFPPLPSRPGFP--PPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP 657
            +P   P G  P  P  P FP  PPTY   PP     G+    PA   + G   +P A  P
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTY---PPYPSPTGA----PAQPPMLGASSRPGAGQP 2223

Query: 658  AG-NQVQAGKQSHIPYSQQ---RPSGPGPMN----QGPQQSQPPSQQPLTSLPAQPTAQS 709
               +    G   H P +     +P  P   N    + P      + +PL S P  P  +S
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP--PFGES 2281

Query: 710  TSQLQVQALTQQQQSPTKAVPALG----KSPPHHSGFQQYQQADASKQLWNP------PQ 759
               L+V+       SP+   P LG     S   H G  + +  D  K    P      PQ
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341

Query: 760  VQG--------PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM---QQQPLEK----KMK 804
              G        P  + +    P +     P    +P  QPP+    Q  P E       +
Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401

Query: 805  PFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQ---ANIDRRGKRSPGVFRPEQDP 861
              P +P++  P+  +       SS S    R + A+    + +  R +      RP   P
Sbjct: 2402 SLPSDPFSRVPASPQSQS----SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457

Query: 862  VPRMPFEKSLLEKPSELMSHSSSFL--SLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAE 919
              R PF    L KP        +F   SL   SL    +P            L +    E
Sbjct: 2458 QSRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFP----------AALPAGPAGE 2505

Query: 920  LSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTP-ASQSPHSSNPSSLPSSPPTHNHNSV 978
            L   +   +   +    GT      P+    + P A   P    P   P  PP H  NS 
Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS- 2564

Query: 979  PFSNFGP---IGTPDNRDRRTAD-----RWKTDKPAMGGFGIDY-LSATSSSESSWHQAS 1029
               +FGP   +G P + +   A            P+ G  G  Y LS           A 
Sbjct: 2565 ---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621

Query: 1030 TPSGTWTGHGPSM-----------EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQ 1078
              S  +  HG S            ED    +  SL +        PG S L Q  +++++
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681

Query: 1079 KQQR 1082
            ++QR
Sbjct: 2682 QRQR 2685



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 79/345 (22%), Positives = 120/345 (34%), Gaps = 35/345 (10%)

Query: 494 LEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSN-NCDTGEKPVVTFKENIK 552
           L  P E+     L+E+ +     +  SP L++ LS     S  +    E P+    E + 
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562

Query: 553 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 612
           T         S PP+E        ++P+S   +      P + S     P   P + PP 
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622

Query: 613 PSR--------PGFPPP-TYVIPPPVAFSMGSGYTFPAGVSVP---GTFLQPTAHSPAGN 660
            SR        P  PPP    + PP   S  S     + +S P        P   SP   
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682

Query: 661 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720
             +A + S  P  +  P+ P P +     + PP +  L SLP + +       + Q   +
Sbjct: 683 PPEASRLS--PPPEDSPTSPPPED---SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737

Query: 721 QQ---QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNP------------PQVQGPLG 765
            +    SP    P L   P       Q ++   S Q   P            PQ +GP  
Sbjct: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-- 795

Query: 766 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEP 810
            + P  +  +L  Q       P  + P +  QP E  + P   EP
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 77/327 (23%), Positives = 118/327 (36%), Gaps = 57/327 (17%)

Query: 662 VQAGKQSHIPYSQQRPSGP----GPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQV 715
           VQ   Q   P +++ P  P     P++  P++S   PP +    S P +    S     +
Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL 483

Query: 716 QALTQQQQSPTKAVPALG--KSPPHHSGFQQYQQADASKQLWNPPQ--VQGPLG---KIM 768
                 ++SP    P       PP  S F   +++  S    +PP   ++ PL    +  
Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543

Query: 769 PVKQPYYLQTQDPIKLFEPSLQPPV---MQQQPLEKKMKPFPME-PYNHNPSEVKVPEFY 824
           P+  P+      P     P+  PP    +   P E  M P P E P +  P   ++   +
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603

Query: 825 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 884
            +S  S     S ++      R    SP    PE  P+   P E+S +  P E+   S  
Sbjct: 604 EESPLSPPPEESPLSPPPEASRL---SPP---PEDSPMSPPP-EESPMSPPPEVSRLSPL 656

Query: 885 FLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL 944
            +                               + LSP   P+E+ L    E +P SP  
Sbjct: 657 PVV------------------------------SRLSPP--PEESPLSPPPEESPTSPP- 683

Query: 945 PASSDHSTPASQSPHSSNPSSLPSSPP 971
           P +S  S P   SP S  P   P+SPP
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPP 710



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 100/438 (22%), Positives = 141/438 (32%), Gaps = 89/438 (20%)

Query: 565 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 624
           PP+         ++P+S   +   T  P +AS     P   P + PP  S    PP    
Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598

Query: 625 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 684
           + PP   S  S                P   SP     +A + S  P  +  P  P P  
Sbjct: 599 LFPPFEESPLS---------------PPPEESPLSPPPEASRLS--PPPEDSPMSPPP-- 639

Query: 685 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-SPPHHSGFQ 743
           +    S PP    L+ LP   +  S    +       ++SPT   P   + SPP      
Sbjct: 640 EESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698

Query: 744 QYQQADA------SKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 797
                D+         L + P  + PL   +P+ +   L  +       P  + P +  +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPL---LPLPEEPQLCPRSEGPHLSPRPEEPHLSPR 755

Query: 798 PLEKKMKPFPMEPY----NHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPG 853
           P E  + P   EP+       P    VPE    S  +   + S   ++ ++      SP 
Sbjct: 756 PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL------SPQ 809

Query: 854 VFRPEQDPVPRMPF---------------EKSLLEKPSELMSHSSSFLSLTGFSLNQERY 898
              P   PVP  P                E  L  +P E  SH S  L     S   E+ 
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKP 867

Query: 899 PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL------PASSDHST 952
           P                   E     AP+E  L+      P  PSL      PA S+   
Sbjct: 868 PE------------------EPGQCPAPEELPLFP----PPGEPSLSPLLGEPALSEPGE 905

Query: 953 PASQSPHSSNPSSLPSSP 970
           P    P S  P  LP SP
Sbjct: 906 P----PLSPLPEELPLSP 919



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 61/229 (26%), Positives = 86/229 (37%), Gaps = 23/229 (10%)

Query: 786 EPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANID 845
           EP L+ P+ ++ PL    +  P+ P          PE    S        S + +  ++ 
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486

Query: 846 RRGKRSPGVFRPEQDPV-------PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERY 898
           R  + SP    PE+ P+       P  P E+S L  P E  S  S  L  T  S   E  
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALE-TPLSPPPEAS 543

Query: 899 PNNSMFNEVY----GKNLTSSSKAELSP-SMAPQETSLYSLFEGTPWSPSLPAS------ 947
           P +  F E       + L +S   E S  S  P+E+ +    E +P SP   AS      
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603

Query: 948 --SDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDR 994
             S  S P  +SP S  P +   SPP  +    P     P+  P    R
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652



 Score = 33.9 bits (76), Expect = 0.86
 Identities = 57/264 (21%), Positives = 96/264 (36%), Gaps = 23/264 (8%)

Query: 549 ENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGA 608
           E+  T     D   S PP++      L   P+ E+   P+ + P     S+   +     
Sbjct: 694 EDSPTSPPPEDSPASPPPED-----SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748

Query: 609 FPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGT-FLQPTAH----SPAGNQVQ 663
            P L  RP  P   ++ P      +      P   +VP    L P A     SP   ++ 
Sbjct: 749 EPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805

Query: 664 AGKQSHIPYSQQRPSGPGPMNQGPQQSQ--PPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 721
              Q+  P+    P  P  ++  P++S   P S++P  S P    +  + +L+   L+ +
Sbjct: 806 LSPQTEEPHLSPVPEEPC-LSPQPEESHLSPQSEEPCLS-PRPEESHLSPELEKPPLSPR 863

Query: 722 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 781
            + P +  P    +P     F    +   S  L  P   +     + P+ +   L     
Sbjct: 864 PEKPPEE-PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG- 921

Query: 782 IKLFEPSLQPPVMQQQPLEKKMKP 805
               EPSL P +M   PL   + P
Sbjct: 922 ----EPSLSPQLMPPDPLPPPLSP 941



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 51/179 (28%), Positives = 62/179 (34%), Gaps = 20/179 (11%)

Query: 661  QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 720
            Q Q  +Q  +   QQ+        Q  Q  Q   QQ L     Q   Q   QLQ Q   Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962

Query: 721  ----QQQSPTKAVPALGKSPPHHSGFQQYQQADA--------SKQLWNPPQVQGPLGKIM 768
                QQQ   + +  L +S    S  QQ QQ  A          Q ++ P   GP   + 
Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLT 4022

Query: 769  PVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDS 827
              +Q     T DP    E +  P   Q  PL     P   E     P EVK P    DS
Sbjct: 4023 GKEQ----NTVDPAVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVK-PSLSGDS 4073



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 17/128 (13%)

Query: 646  PGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP----SQQPLTSL 701
            PGT   P      G Q Q G          +  G GP  QGP +   P    S  P+   
Sbjct: 4246 PGTQTSPL-QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG- 4303

Query: 702  PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQ 761
            P  PT   +S  Q      Q  SP+  +P   + PP H G  + Q           P ++
Sbjct: 4304 PVHPTPPPSSP-QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQ----------GPTLE 4352

Query: 762  GPLGKIMP 769
             P G++ P
Sbjct: 4353 PPPGRVSP 4360



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 40/164 (24%), Positives = 54/164 (32%), Gaps = 4/164 (2%)

Query: 605  HPGAFPPL-PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 663
            HPGA  P  P R      + V+  P     G G      V+      Q   H   G+   
Sbjct: 3814 HPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ-QQQQQHQQQGSMAG 3872

Query: 664  AG--KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 721
                +QS + +S Q      PM    Q  Q    Q    L  Q   Q   Q Q+Q    Q
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932

Query: 722  QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLG 765
            QQ   + +    +        Q  QQ    +Q +   Q Q  +G
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 61/249 (24%), Positives = 88/249 (35%), Gaps = 36/249 (14%)

Query: 567  KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR-PGFPPPTYVI 625
            K+ K  T L     ++ ++    Q   Q  +S  + +  P   P L ++ PG   P + +
Sbjct: 3583 KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALS-PSQSPRLLTKLPGQLLPGHGL 3641

Query: 626  PPPVAFSMGSGYTF---PAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGP 682
             PP     G        P G+++PG    P  ++    Q Q          QQ   G G 
Sbjct: 3642 QPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQ----------QQHSGGAGS 3691

Query: 683  MNQGPQQSQPPSQQPLTSLPA-------------QPTAQSTSQLQVQALTQQQQSPTKAV 729
            +  GP     P    L SL               Q   Q   +LQ Q   QQQQ      
Sbjct: 3692 L-AGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQ 3750

Query: 730  PALGKSPPHHSGFQQYQQADASKQ-LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 788
             A+ +      G Q  Q      Q L  P   QG L + +  + P     Q P  +  P+
Sbjct: 3751 VAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP-----QGPQGMLGPA 3805

Query: 789  LQPPVMQQQ 797
             Q  V+QQQ
Sbjct: 3806 -QVAVLQQQ 3813



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 97/437 (22%), Positives = 148/437 (33%), Gaps = 93/437 (21%)

Query: 584  RKTPVTQTP-TQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSG------ 636
            R+TP  Q P TQ S  Q       G     P   GFP P      P+   +G+G      
Sbjct: 4238 RQTPPYQEPGTQTSPLQ-------GLLGCQPQLGGFPGPQ---TGPLQ-ELGAGPRPQGP 4286

Query: 637  --YTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-PGPMNQGPQQSQPP 693
                 P G    G  L P   +P  +          P   +RPS  P P +Q P ++Q P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSS---------PQEPKRPSQLPSPSSQLPTEAQLP 4337

Query: 694  SQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 753
               P T  P  PT +        A    Q + T     LG   P  +  +  +   +S  
Sbjct: 4338 PTHPGTPKPQGPTLEPPPGRVSPAAA--QLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395

Query: 754  LWNPPQVQG---PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPM-- 808
              +  QV G   P    + +KQ             EP  +P  +  Q ++++    P+  
Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQ-------------EPREEPCALGAQSVKREANGEPIGA 4442

Query: 809  -EPYNH--------NPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRR--------GKRS 851
                NH            + + +     +  ++  R     +A I+           ++ 
Sbjct: 4443 PGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKL 4502

Query: 852  PGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKN 911
             G    ++D   R P    L  KP  +   S   +S    S  + R  +    +E   K 
Sbjct: 4503 QGTPSNKEDAAARKP----LTPKPKRVQKASDRLVS----SRKKLRKEDGVRASEALLKQ 4554

Query: 912  LTSSSKAELSPSMAPQETSLYSLF---------------EGTPWSPSLPASSDHSTPASQ 956
            L    +  L P   P  T+ +SLF                G   S +LP   D+ +    
Sbjct: 4555 L--KQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLT 4612

Query: 957  SPHSSNPSSLPSS-PPT 972
              + SNP + PSS PPT
Sbjct: 4613 KNNLSNPPTPPSSLPPT 4629


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 75/279 (26%), Positives = 93/279 (33%), Gaps = 42/279 (15%)

Query: 566 PKEVKSQTELRKTPVSEARKT-PVTQTPTQASNSQFIPIHHPGAFPP-LPSRPGFPPP-- 621
           P+ VK+     K    +AR T P+  T T  +  Q          P  LP +P   P   
Sbjct: 334 PEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKR 393

Query: 622 TYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-- 679
             V PPP A    +     A V  P     P+   P   Q QA +    P  QQ PS   
Sbjct: 394 ATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLP---QTQAKQPQAPPTPQQTPSTQA 450

Query: 680 ---PGPMNQGPQQSQP----PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQS--PTKAVP 730
              P      PQ  Q       QQ     PAQ     T   Q QA TQQ Q+  P    P
Sbjct: 451 QGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQP 510

Query: 731 ALGKSPPHHSGFQQ-------YQQADASKQLWNPPQV-----------------QGPLGK 766
           A+ + P    G  Q       YQQ    +Q     Q+                 Q P   
Sbjct: 511 AIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMA 570

Query: 767 IMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 805
                QP       P    EP++Q PV QQ  ++    P
Sbjct: 571 AGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPP 609



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 53/214 (24%), Positives = 73/214 (34%), Gaps = 16/214 (7%)

Query: 565 PPKEVKSQTELRKTPVSEA-RKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTY 623
           PP +   QT+ ++       ++TP TQ     + +Q  P H    F     +   PPP  
Sbjct: 423 PPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQ 482

Query: 624 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM 683
             P    +      T       P T     A  P  +Q  + +Q    + QQ        
Sbjct: 483 QQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQ-------- 534

Query: 684 NQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQ---VQALTQQQQSPTKAVPALGKSPPHHS 740
            Q  QQ Q   QQ  T+L  Q      + LQ     A  QQ Q    A P    +P    
Sbjct: 535 -QQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ--PAPAQEP 591

Query: 741 GFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP 773
             Q   +     Q   PP VQG  +G + P   P
Sbjct: 592 AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSP 625


>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
          Length = 463

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 67/291 (23%), Positives = 94/291 (32%), Gaps = 30/291 (10%)

Query: 583 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 642
           A  T     P Q       P+  PG  PP+P  PG PP    + P V   M        G
Sbjct: 122 AASTSFQPQPVQPQQGYIPPMAQPG-LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180

Query: 643 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPG--PMNQGPQQSQPPSQQPLTS 700
           +  PG       H     Q   G+   +P     P GPG  P+  G     PP   P   
Sbjct: 181 MP-PGLH-----HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG----MPPGMPPPVP 230

Query: 701 LPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 760
            P  P       +    +  +  +PT  VPA  + P     F    QA A+        V
Sbjct: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPA-PQPPVTKPLFPSAGQAQAA--------V 281

Query: 761 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKV 820
           QGP+G            T +P K   P+                  P       P+ +  
Sbjct: 282 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341

Query: 821 PE-----FYWDSSYSMADNRSVMAQ-QANIDRRGKRSPGVFRPEQDPVPRM 865
                   + D   S+ + R+ + + Q N+ R G+   G   P   P+  M
Sbjct: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPIGGM 390



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 47/200 (23%), Positives = 68/200 (34%), Gaps = 28/200 (14%)

Query: 598 SQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGV-SVPGTFLQPTAHS 656
           + F P++   A    P +P FP  T       + +  +     A + S P T    +A S
Sbjct: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 346

Query: 657 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 716
              +         I   ++R   P      P+    P Q P+ + P  P       +  Q
Sbjct: 347 KLIHP-----DEDISLEERRAQLPKYQRNLPR----PGQAPIGNPPVGPIG---GMMPPQ 394

Query: 717 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 776
               QQQ     +P  G+   HH G   Y           PP  QGP     P+  PY  
Sbjct: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM------PPYGQGP-----PMVPPYQG 443

Query: 777 QTQDPIKLFEPSLQPPVMQQ 796
               P       ++PPVM Q
Sbjct: 444 GPPRP----PMGMRPPVMSQ 459


>gi|50345881 cytoplasmic polyadenylation element binding protein 3
           [Homo sapiens]
          Length = 698

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 61/293 (20%), Positives = 94/293 (32%), Gaps = 81/293 (27%)

Query: 559 DQGRSFPPKEVKSQTELRKTP---VSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 615
           D+ ++ P  + + + + +  P   VSEA  TP++    +   +  +P   P A PP P+ 
Sbjct: 8   DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67

Query: 616 PGF--------------------PPPTYVIPPPVAFSMGSGYTFPAGVS----------- 644
           P                      PPP     P  + S   G T+  G +           
Sbjct: 68  PDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI 127

Query: 645 --VPGTFL--------QPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPS 694
             V GT L         P        Q+   +  H     Q+P  P P  Q  Q +QPP 
Sbjct: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH----HQQPPPPAPAPQPAQPAQPPQ 183

Query: 695 QQP--LTSLPAQPTAQSTSQLQV------QALTQQQQSPTKAVPALGKSPPHHSGFQQYQ 746
            QP      PA P+    +Q         Q +   + S + AV A   +    S    + 
Sbjct: 184 AQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243

Query: 747 QADASKQLWNPPQ-------------------------VQGPLGKIMPVKQPY 774
              +    W+ P                          V  PL  I P+K+P+
Sbjct: 244 THQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 58/278 (20%), Positives = 97/278 (34%), Gaps = 37/278 (13%)

Query: 779  QDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS---EVKVPEFYWDSSYSMADNR 835
            QD + + +   QP   QQQ   ++ +P P    +  PS     + P+   +S+       
Sbjct: 2    QDDLLMDKSKTQPQPQQQQ--RQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPA 59

Query: 836  SVMAQQANIDRRGKRSPGV------FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLT 889
            +        D+    SP +        P+Q P P+ P        PS   + S+   +  
Sbjct: 60   AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119

Query: 890  GFSLNQERYP-NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASS 948
              S  Q   P N +M  + +  ++        SP +   +T  +   +  P +P+   + 
Sbjct: 120  EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQ 177

Query: 949  DHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMG 1008
                P +Q P      + PS  P    ++       PI               T KP+  
Sbjct: 178  PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI--------------MTSKPSSS 223

Query: 1009 GF--GIDYLSATSSSESSW--HQA-----STPSGTWTG 1037
                     +A SS+ SSW  HQ+     S PS  W G
Sbjct: 224  SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGG 261


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 7/165 (4%)

Query: 602 PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG---VSVPGT-FLQPTAHSP 657
           P+  PG  PP    P    P ++ PP  +     G  FP G   V+ PGT  L PT    
Sbjct: 78  PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIW 137

Query: 658 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA 717
             N+   GK  +  Y+ +          G +  Q     P+ +  AQ  AQ+ +Q Q QA
Sbjct: 138 VENKTPDGKVYY--YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195

Query: 718 LTQQQQSPTKAVPALGKSPPHHSGFQQYQ-QADASKQLWNPPQVQ 761
             Q Q        A  ++        Q Q QA A  Q     Q Q
Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 58/294 (19%), Positives = 98/294 (33%), Gaps = 38/294 (12%)

Query: 560 QGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP 619
           Q ++    +V++Q + +    +    TP T +P  A ++               S P   
Sbjct: 234 QAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTS-----------TSSSTPSST 282

Query: 620 PPTYVIPPPVAFSMGS----GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH------ 669
             T      VA ++ +      T  + VSV    +  +  +P    VQ   Q H      
Sbjct: 283 TSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPP 342

Query: 670 -IPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKA 728
            +P+S  +P+   P    P    PP + PL  +P                    Q    A
Sbjct: 343 AVPHSVPQPTTAIPAF--PPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAA 400

Query: 729 VPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 788
            PA        S + +Y+ AD     +N   ++    K   +K+   L+     K+ EP 
Sbjct: 401 SPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE----KIKEPI 456

Query: 789 LQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQA 842
            +P            +P PME    +P E  + E   +            AQ+A
Sbjct: 457 KEP----------SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKA 500



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 26/152 (17%)

Query: 606 PGAFPPL--PSRPGFPP----------PTYVIPPPVAFSMGSGYTFPAGVSV-------P 646
           P   PP+  P  P  PP          P   +    A +  S +T P GV V       P
Sbjct: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175

Query: 647 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQ-QPLTSLPAQP 705
               Q    + A  Q QA  Q+      Q  +      Q   Q+Q  +Q Q      AQ 
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235

Query: 706 TAQSTSQLQVQALTQQQ------QSPTKAVPA 731
            AQ+ +Q+Q Q   Q Q       +PT + PA
Sbjct: 236 QAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,179,113
Number of Sequences: 37866
Number of extensions: 2527695
Number of successful extensions: 15107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 782
Number of HSP's that attempted gapping in prelim test: 10636
Number of HSP's gapped (non-prelim): 3854
length of query: 1091
length of database: 18,247,518
effective HSP length: 113
effective length of query: 978
effective length of database: 13,968,660
effective search space: 13661349480
effective search space used: 13661349480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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