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Search of human proteins with 33589824
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33589824 cell growth regulator with EF-hand domain 1 [Homo
sapiens]
(301 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33589824 cell growth regulator with EF-hand domain 1 [Homo sa... 598 e-171
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 57 3e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 3e-08
gi|33286446 opioid growth factor receptor [Homo sapiens] 49 4e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 49 4e-06
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 49 4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 46 4e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 46 4e-05
gi|21281683 multiple coagulation factor deficiency 2 [Homo sapiens] 46 5e-05
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 45 6e-05
gi|38176300 nestin [Homo sapiens] 45 8e-05
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho... 44 1e-04
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 44 2e-04
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H... 44 2e-04
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho... 44 2e-04
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom... 44 2e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 44 2e-04
gi|30795231 brain abundant, membrane attached signal protein 1 [... 44 2e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 43 3e-04
gi|217035154 RCSD domain containing 1 [Homo sapiens] 43 3e-04
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 43 4e-04
gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens] 43 4e-04
gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens] 43 4e-04
gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens] 43 4e-04
gi|226053126 paternally expressed 3 isoform 1 [Homo sapiens] 43 4e-04
gi|33354285 paternally expressed 3 isoform 1 [Homo sapiens] 43 4e-04
gi|153070260 myristoylated alanine-rich protein kinase C substra... 42 5e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 42 5e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 42 5e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 42 5e-04
>gi|33589824 cell growth regulator with EF-hand domain 1 [Homo
sapiens]
Length = 301
Score = 598 bits (1543), Expect = e-171
Identities = 301/301 (100%), Positives = 301/301 (100%)
Query: 1 MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGR 60
MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGR
Sbjct: 1 MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGR 60
Query: 61 TEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVD 120
TEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVD
Sbjct: 61 TEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVD 120
Query: 121 KVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQE 180
KVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQE
Sbjct: 121 KVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQE 180
Query: 181 TQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG 240
TQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG
Sbjct: 181 TQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG 240
Query: 241 EAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDE 300
EAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDE
Sbjct: 241 EAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDE 300
Query: 301 I 301
I
Sbjct: 301 I 301
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 56.6 bits (135), Expect = 3e-08
Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPR 239
E +E G EE +G+ E E + +E G + E +G+ GE EG+ E +G+
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEG-EEEGEEGEGEGEEE--EGEGEGEEEGEGEGEEEE 899
Query: 240 GEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGE 278
GE G+ E EG+ GE G+ E E E +E GE
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 56.2 bits (134), Expect = 3e-08
Identities = 40/115 (34%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPR 239
E +E G EE +G+ E E + E G+ E +G+ GE E + E +G+ G
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE---GEGEEEEEGEVEGEVEGEE 1029
Query: 240 GEAGGQAEAEGDAPGPRGEAGGQAEA-RENGEEAKELPG---ETLESKNTQNDFE 290
GE G+ E EG+ G E G+ E R N EE +E G ET E +N + D E
Sbjct: 1030 GEGEGE-EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGE 1083
Score = 55.8 bits (133), Expect = 4e-08
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPG-GQAEADGDVPGPRGEAEGQAE-AKGDAPG 237
E +E G E+ +G+ E + +E G G+ E +G+ G GE EG+ E +G+
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 238 PRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFE 290
GE G+ E EG+ G G+ E E GE E+ GE E + + + E
Sbjct: 993 EEGEEEGEEEGEGEEEGE-----GEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/124 (30%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPG-GQAEAD-GDVPGPRGEAEGQAEAKGDAP 236
+E E G E +G+ E E + E G G+ E + G+ G E EG+ E +G+
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 237 GPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQV 296
G GE G+ E EG+ G E + E GEE E GE E + + E +
Sbjct: 974 GEEGEGEGEEE-EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 297 ENDE 300
E +E
Sbjct: 1033 EGEE 1036
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPR 239
E E G EE +G+ E E +E G+ E +G+ G E EG+ E +G+
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE----E 927
Query: 240 GEAGGQAEAEGDAPGPRGEAGGQAEARE----------NGEEAKELPGETLESKNTQNDF 289
GE G+ E EG+ G GE G+ E E GEE E GE E + + +
Sbjct: 928 GEGEGE-EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986
Query: 290 EVHIVQVENDE 300
E + E +E
Sbjct: 987 EGEGEEEEGEE 997
Score = 52.0 bits (123), Expect = 6e-07
Identities = 38/118 (32%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGP 238
+E E G EE +G+ E E + G E +G+ G GE EG+ E +G+ G
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGE-----EGEGEGEEEEGEGEGEDGEGEGEEE-EGEWEGE 958
Query: 239 RGEAGGQAEAEGDAPGPRGEAGGQAE------ARENGEEAKELPGETLESKNTQNDFE 290
E G+ E EG+ G GE G+ E E GEE E GE E + + E
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/103 (34%), Positives = 49/103 (47%), Gaps = 6/103 (5%)
Query: 186 GPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQ---AEAKGDAPGPRGEA 242
G EE KG+ E E + +E G E +G+ GE +G+ E +G+ G GE
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG 876
Query: 243 GGQAEAEGDAPG-PRGEAGGQAEARE-NGEEAKELPGETLESK 283
G+ E EG+ G GE G+ E E GEE E GE E +
Sbjct: 877 EGE-EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Score = 46.2 bits (108), Expect = 4e-05
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 13/108 (12%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGG-----QAEADGDVPGPRGEAEGQAEAKGD 234
E +E G EE +G+ E E + G + E +G+V G GE EG+ E +G+
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEE-EGE 1040
Query: 235 APGPRGEAGGQAEA-------EGDAPGPRGEAGGQAEARENGEEAKEL 275
G E G+ E E + G E G + R++GEE K++
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKV 1088
Score = 45.8 bits (107), Expect = 5e-05
Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGG----QAEADGDVPGPRGEAE-----GQAE 230
E +E G REE + + E E + +E G + E G+ G GE E G+ E
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 231 AKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEA-RENGEEAKELPGETLESKNTQNDF 289
+ + GE G+ E E + GE G+ E E GE E GE E + + +
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 290 E 290
E
Sbjct: 938 E 938
Score = 42.4 bits (98), Expect = 5e-04
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 182 QEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGE 241
+E G EE +G+ E + +E G E +G+ GE E + E + GE
Sbjct: 968 EEGEGEGEEGEGEGEEEEGEGEGEEEEG---EEEGE---EEGEGEEEGEGE-------GE 1014
Query: 242 AGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFE 290
+ E EG+ G GE G+ E E E +E GE E++ + + E
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/117 (29%), Positives = 50/117 (42%), Gaps = 16/117 (13%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQA--------E 230
+E + G EE +G+ E + E + GG+ E +G E EG+ E
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEG---GEVEGGEVE-EGKGEREEEEEEGEGEEEEGEGEE 844
Query: 231 AKGDAPGPRGEAGGQ---AEAEGDAPGPRGEAGGQAEARE-NGEEAKELPGETLESK 283
+G+ GE G+ E EG+ G GE G+ E E GEE E GE E +
Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Score = 38.9 bits (89), Expect = 0.006
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQ--AEAKGDAP 236
+E +E +EE G+ E E D + + E G+ GE EG E KG+
Sbjct: 768 REKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGERE 827
Query: 237 GPRGEAGGQAEAEGDAPGPRGEA---GGQAEARENGEEAK-ELPGETLESKNTQNDFE 290
E G+ E EG+ GE G+ + E GEE + E GE E + + + E
Sbjct: 828 EEEEEGEGE-EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 7/103 (6%)
Query: 180 ETQEAPGPREEAKGQ--VEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPG 237
E +E G RE+ +G+ E R + +E G Q E + + RGE + E G+ G
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE---EKEEGGEVEG 816
Query: 238 PRGE--AGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGE 278
E G + E E + G E G+ E E EE E GE
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859
Score = 37.0 bits (84), Expect = 0.021
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 7/111 (6%)
Query: 178 RQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPG 237
++E ++ G +E K + + ++ + E GG+ E G E EG E + + G
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH-----GEGEEEEGDREEEEEKEG 753
Query: 238 PRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQND 288
E G E EG+ GE + E R EE E G+ E + + +
Sbjct: 754 EGKEEGEGEEVEGEREKEEGER--KKEERAGKEEKGEEEGDQGEGEEEETE 802
Score = 37.0 bits (84), Expect = 0.021
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 13/117 (11%)
Query: 178 RQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPG 237
R + E G E +G+ E + +E G+ E +G+ E EG+ E K +
Sbjct: 723 RNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE------EVEGERE-KEEGER 775
Query: 238 PRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKE----LPGETLESKNTQNDFE 290
+ E G+ E +G+ G +GE G + E GEE +E GE E K + + E
Sbjct: 776 KKEERAGK-EEKGEEEGDQGE-GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEE 830
Score = 28.9 bits (63), Expect = 5.8
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 3/54 (5%)
Query: 223 GEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAG-GQAEARENGEEAKEL 275
GEAE E +GD G +G AE D +GE G+ E GE KEL
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSG--AEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 15/130 (11%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGD-VPGPRGEAEGQAEAKGDAPG 237
+E QEA G +EA+G+ E +D QE G+A+ + + V P E E Q +AP
Sbjct: 2062 EEAQEAEGEVQEAEGEAHPESEDVD-AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 238 PRGEAGGQAEAEG-DAPGPRGEAGGQAEARENGEEAKELPGET------LESKNTQNDFE 290
GEA Q E+EG +AP EA G+A+ G EA++ GE +E++ + + +
Sbjct: 2121 TEGEA--QPESEGIEAP----EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174
Query: 291 VHIVQVENDE 300
+ VE E
Sbjct: 2175 PELEGVEAPE 2184
Score = 48.1 bits (113), Expect = 9e-06
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 12/127 (9%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQ-EPGGQAEADGDVPGPRGEAEGQAEAKGDAPGP 238
E QEA +EA+GQ + E ++ + E Q E++ DV E E Q EA+G+A P
Sbjct: 1939 EAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESE-DVEALEVEVETQ-EAEGEAQ-P 1995
Query: 239 RGEAGGQAEAEGDAPGPRGEA-----GGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
E EAEG+ EA G +A+ + GEEA+E+ GET + T+ D +
Sbjct: 1996 ESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGET---QKTEGDAQPES 2052
Query: 294 VQVENDE 300
VE E
Sbjct: 2053 DGVEAPE 2059
Score = 47.8 bits (112), Expect = 1e-05
Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 11/110 (10%)
Query: 179 QETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQA------EAK 232
+E QE G ++ +G + + ++ + EA+G+V GEA ++ EA+
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 233 GDAPGPRGEAGGQAEAEGDAPGPRG----EAGGQAEARENGEEAKELPGE 278
G+A P E EAEG+A G E G+A+ G EA E GE
Sbjct: 2092 GEAQ-PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGE 2140
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/124 (34%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 173 AKSPLRQETQEAPG--PREEAKGQVEARRESLDPVQEPGGQAEADGDV-PGPRGEAEG-- 227
A S L + QE G R E GQ ++L G+A A GD PG AEG
Sbjct: 1783 AGSELGEAEQEGEGISERGETGGQGSGHEDNLQ------GEAAAGGDQDPGQSDGAEGIE 1836
Query: 228 QAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQN 287
EA+G+A P E EAEGDA GEA ++E E E E E+ + + +
Sbjct: 1837 APEAEGEAQ-PESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEA 1895
Query: 288 DFEV 291
++EV
Sbjct: 1896 EWEV 1899
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 22/144 (15%)
Query: 162 EPQAVGRQSLLAKSPLRQ---ETQEAPGPREEAKGQVEARRESLD--------PVQEPGG 210
EP++ G ++ A+ ++ +TQ E + + EA+ ES D QE G
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 211 QAEADG-DVPGPRGEAE-------GQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQ 262
+A+ + DV P E E Q E+ G P+ E E EG+ G+A +
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPE 2051
Query: 263 A---EARENGEEAKELPGETLESK 283
+ EA E EEA+E GE E++
Sbjct: 2052 SDGVEAPEAEEEAQEAEGEVQEAE 2075
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 157 APSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLD-PVQEPGGQAEAD 215
A +P++ G ++ A+ + E + P EA+G+ + E ++ P E Q E +
Sbjct: 2153 AEGEAQPESEGIEAQEAEEEAQPELEGVEAP--EAEGEAQPESEGIEAPEAEGEAQPELE 2210
Query: 216 GDVPGPRGEAEGQAEAKG-DAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKE 274
G V P E E Q E +G + P GEA Q E+EG+ G + + + EEA E
Sbjct: 2211 G-VEAPEAEEEAQPEPEGVETPEAEGEA--QPESEGETQGEKKGSPQVSLGDGQSEEASE 2267
Query: 275 LPGETLESKNT 285
E + T
Sbjct: 2268 SSSPVPEDRPT 2278
Score = 42.7 bits (99), Expect = 4e-04
Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 13/135 (9%)
Query: 154 EPLAPSPQEPQAVGRQSLLAKSPLRQETQ-EAPGPREEAKGQVEARRESLDPVQEPGGQA 212
+P + + P+A G +E Q E+ G + K + E +E Q+ G A
Sbjct: 1994 QPESEDVEAPEAEGEMQ-----EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDA 2048
Query: 213 EADGD-VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEE 271
+ + D V P E E Q EA+G+ EA G+A E + + EA G+A+ G E
Sbjct: 2049 QPESDGVEAPEAEEEAQ-EAEGEVQ----EAEGEAHPESEDVDAQ-EAEGEAQPESEGVE 2102
Query: 272 AKELPGETLESKNTQ 286
A E GE +++ +
Sbjct: 2103 APEAEGEAQKAEGIE 2117
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 20/111 (18%)
Query: 180 ETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKG----DA 235
E EA G ++A+G +EA P E Q E++G + P E E Q E++G DA
Sbjct: 2102 EAPEAEGEAQKAEG-IEA------PETEGEAQPESEG-IEAPEAEGEAQPESEGVEAQDA 2153
Query: 236 PG---PRGEAGGQAEAEGDA-PGPRG----EAGGQAEARENGEEAKELPGE 278
G P E EAE +A P G EA G+A+ G EA E GE
Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204
Score = 38.5 bits (88), Expect = 0.007
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 202 LDPVQEPGGQAEADGDVPGPRGEAEGQA---EAKGDAPGPRGEAG---GQAEAEGDAPGP 255
+D ++ G + D GEAEG A E +G AG G+AE EG+
Sbjct: 1740 VDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISE 1799
Query: 256 RGEAGGQAEARENGEEAKELPG 277
RGE GGQ E+ + + G
Sbjct: 1800 RGETGGQGSGHEDNLQGEAAAG 1821
Score = 36.2 bits (82), Expect = 0.036
Identities = 32/121 (26%), Positives = 46/121 (38%), Gaps = 26/121 (21%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQA---EADGDVPGPR---GEAEGQAEAKGDAPGPRGEA 242
E+ +G R+ + E G A E +G G G+AE +G+ RGE
Sbjct: 1744 EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGET 1803
Query: 243 GGQAEAE----------------GDAPGPRG----EAGGQAEARENGEEAKELPGETLES 282
GGQ G + G G EA G+A+ G EA E G+ E+
Sbjct: 1804 GGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEA 1863
Query: 283 K 283
+
Sbjct: 1864 E 1864
Score = 35.8 bits (81), Expect = 0.048
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 10/128 (7%)
Query: 157 APSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQ-----VEARRESLDPVQEPGG- 210
A +P+ G ++ A+ + E++ P E + Q VEA + EP G
Sbjct: 2169 AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228
Query: 211 -QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENG 269
EA+G+ P E E Q E KG G+ GQ+E ++ P E G
Sbjct: 2229 ETPEAEGEAQ-PESEGETQGEKKGSPQVSLGD--GQSEEASESSSPVPEDRPTPPPSPGG 2285
Query: 270 EEAKELPG 277
+ + PG
Sbjct: 2286 DTPHQRPG 2293
Score = 30.0 bits (66), Expect = 2.6
Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 160 PQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPG--GQAEADGD 217
P+EP +L L ET A G SL+ + EP GQ +GD
Sbjct: 965 PEEP-------ILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGD 1017
Query: 218 VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA-EGDAPGPRGEAGGQAEA 265
PG E EG D GE Q A EG + P EAG EA
Sbjct: 1018 -PGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAP-AEAGADREA 1064
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 49.3 bits (116), Expect = 4e-06
Identities = 54/171 (31%), Positives = 68/171 (39%), Gaps = 15/171 (8%)
Query: 124 ETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQE 183
+T+ G TP PG + EP A SP E P + E
Sbjct: 503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEP-AESPSETPGPRPAGPAGDEPA-ESPSE 560
Query: 184 APGPREEAK-GQVEARRESLDPVQEPGGQ-----AEADGDVPGPR--GEAEGQ-AEAKGD 234
PGPR G A S P P G AE+ + PGPR G A + AE+ +
Sbjct: 561 TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSE 620
Query: 235 APGPR--GEAGGQ-AEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLES 282
PGPR G AG + AE+ + PGP AG + EA EL +ES
Sbjct: 621 TPGPRPAGPAGDEPAESPSETPGP-SPAGPTRDEPAKAGEAAELQDAEVES 670
Score = 33.9 bits (76), Expect = 0.18
Identities = 42/155 (27%), Positives = 57/155 (36%), Gaps = 39/155 (25%)
Query: 155 PLAPSPQEPQAVGRQSL------LAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEP 208
P P PQ V + +L L++ LR TQE G + E++ P ++P
Sbjct: 396 PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG---------QDPGEAVQPCRQP 446
Query: 209 GGQAEADGDVPGPR---GEAEGQAEAKGDA--------PGPRG-------EAGGQAEAEG 250
G AD + G + A A G A P P G E G + + EG
Sbjct: 447 LGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEG 506
Query: 251 ------DAPGPRGEAGGQAEARENGEEAKELPGET 279
PG E G + A G+E E P ET
Sbjct: 507 RTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSET 541
Score = 29.6 bits (65), Expect = 3.4
Identities = 34/127 (26%), Positives = 44/127 (34%), Gaps = 18/127 (14%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
+PGE + P Q A + K R++ E G A A+ +L P G
Sbjct: 435 DPGEAVQPCRQPLGA----RVADKVRKRRKVDEGAGD-SAAVASGGAQTLALAGSPAPSG 489
Query: 211 QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGE 270
+A G + EG+ K PG E G P P G AG E E
Sbjct: 490 HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPG--------PSPAGPAGD-----EPAE 536
Query: 271 EAKELPG 277
E PG
Sbjct: 537 SPSETPG 543
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 49.3 bits (116), Expect = 4e-06
Identities = 39/146 (26%), Positives = 59/146 (40%), Gaps = 20/146 (13%)
Query: 162 EPQAVGRQSLLAKSPLR-QETQEAPGPREEAKGQVEARRESLDPVQEPGGQ-----AEAD 215
+PQA + P + P P + KG D + PGGQ AE+
Sbjct: 703 QPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG---------DQKENPGGQEDVAEAEST 753
Query: 216 GDVPGPRGEAEGQAEAKGDAPG---PRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEA 272
G++PG GE G+ E + + G P GE G+ E +G E + + GE+
Sbjct: 754 GEMPGEEGETAGEGETEEKSGGETQPEGE--GETETQGKGEECEDENEAEGKGDNEGEDE 811
Query: 273 KELPGETLESKNTQNDFEVHIVQVEN 298
E+ E E K + + E + EN
Sbjct: 812 GEIHAEDGEMKGNEGETESQELSAEN 837
Score = 45.8 bits (107), Expect = 5e-05
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
Query: 177 LRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEAD---GDVPGPRGEAEGQAEAKG 233
++ + +E PG +E+ + E+ E E G+ E + G P GE E + + KG
Sbjct: 733 IKGDQKENPGGQEDV-AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKG 791
Query: 234 DAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETL-ESKNTQNDFE 290
+ EA G+ + EG+ G G+ + E E++EL E E+KN + E
Sbjct: 792 EECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVE 849
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 16/137 (11%)
Query: 168 RQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQ------EPGGQAEADGDVPGP 221
R+ LAK ++E G R + + + E++ E +P + P + GD
Sbjct: 683 REVRLAKE--KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKEN 740
Query: 222 RGEAEGQAEAK--GDAPGPRGEAGGQAEAEGDAPG---PRGEAGGQAEARENGEEAK-EL 275
G E AEA+ G+ PG GE G+ E E + G P GE G+ E + GEE + E
Sbjct: 741 PGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGE--GETETQGKGEECEDEN 798
Query: 276 PGETLESKNTQNDFEVH 292
E +++ E+H
Sbjct: 799 EAEGKGDNEGEDEGEIH 815
Score = 39.7 bits (91), Expect = 0.003
Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 15/134 (11%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
E GE E ++ G P + E G EE + + EA + + ++ G
Sbjct: 759 EEGETAGEGETEEKSGGETQ-----PEGEGETETQGKGEECEDENEAEGKGDNEGEDEGE 813
Query: 211 QAEADGDVPGPRGEAEGQ-------AEAKGDAPGPR---GEAGGQAEAEGDAPGPRGEAG 260
DG++ G GE E Q EAK D G G GG +E E + + E
Sbjct: 814 IHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE 873
Query: 261 GQAEARENGEEAKE 274
+ E E EE +E
Sbjct: 874 EEEEQEEEEEEEEE 887
Score = 36.6 bits (83), Expect = 0.028
Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 20/171 (11%)
Query: 134 MTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKG 193
+TPA + + G + E +A + + G + A ET+E G + +G
Sbjct: 725 VTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEG---ETEEKSGGETQPEG 781
Query: 194 QVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAK-GDAPGPRGEAGGQ------- 245
+ E + E +AE GD GE EG+ A+ G+ G GE Q
Sbjct: 782 EGETETQGKGEECEDENEAEGKGD---NEGEDEGEIHAEDGEMKGNEGETESQELSAENH 838
Query: 246 AEAEGDAPGPR---GEAGGQAEARENG---EEAKELPGETLESKNTQNDFE 290
EA+ D G G GG +E E +E +E E E + + + E
Sbjct: 839 GEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 49.3 bits (116), Expect = 4e-06
Identities = 53/154 (34%), Positives = 66/154 (42%), Gaps = 24/154 (15%)
Query: 137 AELINFPGVALRHVEPGE---PLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKG 193
AE GVA P E PLA P EP A G ++ E E EEA
Sbjct: 2 AEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEA---------EGPEGSEGAEEAPR 52
Query: 194 QVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG--EAGGQAEAEGD 251
A +E+ + G +AEA G G GE E + A A P+G E G + EG
Sbjct: 53 GAAAVKEAGGGGPDRGPEAEARG-TRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGA 111
Query: 252 APG------PRGEAGGQAE---ARENGEEAKELP 276
+PG PRGEA + E A E EEA++ P
Sbjct: 112 SPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRP 145
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/91 (36%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 204 PVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG-----EAGG---QAEAEGDAPGP 255
P + P AE G+ GEAEG ++G PRG EAGG E +A G
Sbjct: 17 PPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGT 76
Query: 256 RGEAGGQAEARENGEEAKELPGETLESKNTQ 286
RG A G+ EA E E E+P E+ Q
Sbjct: 77 RG-AHGETEAEEGAPEGAEVPQGGEETSGAQ 106
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 11/101 (10%)
Query: 175 SPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGD 234
S +Q +PG + + + EA+RE D P Q EA+ P G A G+A D
Sbjct: 103 SGAQQVEGASPGRGAQGEPRGEAQREPEDSAA-PERQEEAEQRPEVPEGSASGEAGDSVD 161
Query: 235 APGPRGE-------AGGQAEAEG---DAPGPRGEAGGQAEA 265
A GP G+ AG EAEG D+ G AG +A
Sbjct: 162 AEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDA 202
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 173 AKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRG---EAEGQA 229
A+ R E Q P + Q EA + P G+A D GP G EAEG A
Sbjct: 117 AQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPA 176
Query: 230 EAKGDAPGPRGEAGGQAEAEG------DAPGPRGEAGGQAEARENGEEAKELPGETLESK 283
GD+ G G +AEG DA GP G+ + +A+ G++++++
Sbjct: 177 ---GDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAE 233
Query: 284 NTQND 288
D
Sbjct: 234 GPAGD 238
Score = 38.5 bits (88), Expect = 0.007
Identities = 36/98 (36%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 186 GPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEA--- 242
G +A+G+V E+ D P G G G EAEG A DA GP G A
Sbjct: 237 GDSVDAEGRVGDSVEAGD----PAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRV 292
Query: 243 GGQAEAEGDAPGPRGEAGGQAEARE--NGEEAKELPGE 278
G+ + GD G QAEA E GE A PGE
Sbjct: 293 SGEPQQSGD-----GSLSPQAEAIEVAAGESAGRSPGE 325
Score = 37.0 bits (84), Expect = 0.021
Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 20/131 (15%)
Query: 150 VEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPV---- 205
VE G P S + G S+ A+ P + + + P++ G + + E+++
Sbjct: 260 VEAGVPAGDSVEAEGPAG-DSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES 318
Query: 206 --QEPGG---QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAG 260
+ PG A + +VPG +G E A GDA GE + GD GP+ E G
Sbjct: 319 AGRSPGELAWDAAEEAEVPGVKGSEEA---APGDARADAGE-----DRVGD--GPQQEPG 368
Query: 261 GQAEARENGEE 271
E RE E
Sbjct: 369 EDEERRERSPE 379
Score = 35.4 bits (80), Expect = 0.062
Identities = 46/176 (26%), Positives = 68/176 (38%), Gaps = 36/176 (20%)
Query: 158 PSPQEPQAVGR--QSLLAKSPLRQ--ETQEAPGPREEAKGQVEARRESLDPVQEPGGQAE 213
P E A G S+ A+ PL E + G EA+G+V +S+D G +
Sbjct: 145 PEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVG---DSVDAEGPAGDSVD 201
Query: 214 ADGDV------PGPRGE---AEGQAEAKGDAPGPRGE-----------------AGGQAE 247
A+G + GP G+ AEG+ DA GP G+ AG E
Sbjct: 202 AEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVE 261
Query: 248 A---EGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDE 300
A GD+ G AG +A A+ + GE +S + + ++V E
Sbjct: 262 AGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/139 (33%), Positives = 58/139 (41%), Gaps = 16/139 (11%)
Query: 142 FPGVALRHVEPGEPLAPSPQ----EPQAVGRQSLL--AKSPLRQETQEAPGP--REEAKG 193
FPG+ EPG+ AP P VG L A P R+ + A GP R+ A G
Sbjct: 994 FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 1053
Query: 194 QVEARRESLDPVQEPGGQAEADGDVP-GPRGEAEGQAEAKGDAP-GPRGEAGGQAEAEGD 251
V+ R V PG P GP G+ + EA P GP G AG +
Sbjct: 1054 -VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG----- 1107
Query: 252 APGPRGEAGGQAEARENGE 270
GP+G G + EA E GE
Sbjct: 1108 IQGPQGPRGDKGEAGEPGE 1126
Score = 41.6 bits (96), Expect = 9e-04
Identities = 50/159 (31%), Positives = 59/159 (37%), Gaps = 39/159 (24%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA 191
G P FPG A R PG P P P PGP +
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP---------------------PGPSGK- 925
Query: 192 KGQVEARRESLDP--VQEPGGQAEADGDVPGPRGEA--EGQAEAKGDAPGPRGEAG---- 243
G AR +S P EPG Q A PG +GE +G + A+G PGP+G AG
Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGDDGPSGAEG-PPGPQGLAGQRGI 982
Query: 244 ----GQAEAEG--DAPGPRGEAGGQAEARENGEEAKELP 276
GQ G PGP GE G Q +G+ P
Sbjct: 983 VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/100 (37%), Positives = 45/100 (45%), Gaps = 17/100 (17%)
Query: 185 PGPREEAKGQ-VEARRESLDPVQEPG--GQAEADGDVPGPRGEAEGQAEAKGDA--PGPR 239
PGP A + R P G G ADG PG +GE +G+A KGDA PGP+
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ-PGAKGE-QGEAGQKGDAGAPGPQ 866
Query: 240 GEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGET 279
G +G APGP+G G G A+ PG T
Sbjct: 867 GPSG--------APGPQGPTGVTGPKGARG--AQGPPGAT 896
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 23/141 (16%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAV----GRQSLLAKSPLRQETQE-----APGPREEAKG 193
PGV PGE +P P P+ + GR + R + PGP A G
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364
Query: 194 QVEARRESLDPVQEPGGQAEADGDVPGPRGE-----AEGQAEAKGD-----APGPRGEAG 243
P G +G GPRGE + G A A G+ PG +G AG
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEG-AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG 423
Query: 244 --GQAEAEGDAPGPRGEAGGQ 262
G A A G PGPRG G Q
Sbjct: 424 APGIAGAPG-FPGPRGPPGPQ 443
Score = 36.6 bits (83), Expect = 0.028
Identities = 37/128 (28%), Positives = 48/128 (37%), Gaps = 29/128 (22%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
EPGEP P P+ PGP + EA + + P G
Sbjct: 229 EPGEPGVSGPMGPRG------------------PPGPPGKPGDDGEAGKPGKAGERGPPG 270
Query: 211 QAEADG-----DVPGPRGEA--EGQAEAKGDA--PGPRGEAGGQAEAEGDAPGPRGEAGG 261
A G +PG +G G AKG+A PG +GE+G + E +PGP G G
Sbjct: 271 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESG--SPGENGSPGPMGPRGL 328
Query: 262 QAEARENG 269
E G
Sbjct: 329 PGERGRTG 336
Score = 36.6 bits (83), Expect = 0.028
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 21/147 (14%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA 191
GL+ P FPG E G P A Q P+ L +P + A GP
Sbjct: 693 GLVGPRGERGFPG------ERGSPGAQGLQGPRG------LPGTPGTDGPKGASGPAGPP 740
Query: 192 KGQVEARRESLDPVQEPGGQAEADGD-----VPGPRGEAEGQAEAKG--DAPGPRGEAGG 244
Q + + + G A GD GP G A G+ +G GP G AG
Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGA 799
Query: 245 QAE-AEGDAPGPRGEAGGQAEARENGE 270
E E PGP G AG + E GE
Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGE 826
Score = 35.8 bits (81), Expect = 0.048
Identities = 45/136 (33%), Positives = 54/136 (39%), Gaps = 15/136 (11%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG R EPG P P P P L + Q A G E+A G L
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN---FAAQMAGGFDEKAGGA------QL 196
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAG--GQAEAEGDAPGPRGEAG 260
+Q P G G PGP G A G +G+ PG GE G G G PGP G+ G
Sbjct: 197 GVMQGPMGPMGPRGP-PGPAG-APGPQGFQGN-PGEPGEPGVSGPMGPRGP-PGPPGKPG 252
Query: 261 GQAEARENGEEAKELP 276
EA + G+ + P
Sbjct: 253 DDGEAGKPGKAGERGP 268
Score = 35.8 bits (81), Expect = 0.048
Identities = 46/159 (28%), Positives = 61/159 (38%), Gaps = 26/159 (16%)
Query: 151 EPGEPLAPSPQE----------PQAVGRQSL--LAKSPLRQETQEAPGPREEAKGQVEAR 198
EPG P +P P P A G +A +P + PGP + A G + +
Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QGATGPLGPK 452
Query: 199 RESLDP-------VQEPGGQAEADGD--VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAE 249
++ +P Q P G+ G PGP GE EG+ A+G+ PG G G E
Sbjct: 453 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE-EGKRGARGE-PGGVGPIGPPGER- 509
Query: 250 GDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQND 288
APG RG G A G + P K D
Sbjct: 510 -GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGD 547
Score = 35.8 bits (81), Expect = 0.048
Identities = 48/173 (27%), Positives = 64/173 (36%), Gaps = 26/173 (15%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPG----- 186
GL PA PG + G A P PQ + Q + P ++ + PG
Sbjct: 945 GLQGPA---GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001
Query: 187 --PREEAKGQVEARRESLDPVQEPG-----GQAEADGD--VPGPRGEAEGQAEAKGDAPG 237
P ++ R PV PG G+ +G GP G +G A KGD
Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGR-DGAAGVKGD--- 1057
Query: 238 PRGEAG--GQAEAEGD--APGPRGEAGGQAEARENGEEAKELPGETLESKNTQ 286
RGE G G A G +PGP G G Q + E G + P ++ Q
Sbjct: 1058 -RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109
Score = 34.7 bits (78), Expect = 0.11
Identities = 23/56 (41%), Positives = 27/56 (48%), Gaps = 7/56 (12%)
Query: 208 PGGQAEADGDVP---GPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAG 260
P GQ GD+ GP+G Q A GPRG+ G + E APGPRG G
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPA--GEQGPRGDRGDKGEK--GAPGPRGRDG 153
Score = 33.9 bits (76), Expect = 0.18
Identities = 42/128 (32%), Positives = 49/128 (38%), Gaps = 31/128 (24%)
Query: 152 PGEPLAPSPQ----EPQAVGRQSLLAKS--PLRQETQEAPGPREEAKGQVEARRESLDPV 205
PGEP P + P G Q + S P PGP + A+GQ
Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQ----------- 598
Query: 206 QEPGGQAEADGDVPGPRGE--AEGQAEAKG--DAPGPRGEAGGQAEAEGDAPGPRGEAGG 261
PG PGP+G G+A KG APG RG G + E A GP G AG
Sbjct: 599 --PGVMG-----FPGPKGANGEPGKAGEKGLPGAPGLRGLPG--KDGETGAAGPPGPAGP 649
Query: 262 QAEARENG 269
E E G
Sbjct: 650 AGERGEQG 657
Score = 33.9 bits (76), Expect = 0.18
Identities = 43/143 (30%), Positives = 52/143 (36%), Gaps = 19/143 (13%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA--KGQVEARRE 200
PG A PG P + Q Q A +P Q APGP+ G AR
Sbjct: 830 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889
Query: 201 SLDP-----------VQEPGGQAE-ADGDVPGPRGEAEGQAEAKGDA--PGPRGEAGGQA 246
P V PG PGP G+ +G A+GD+ PG GE G Q
Sbjct: 890 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK-DGPKGARGDSGPPGRAGEPGLQG 948
Query: 247 EAEGDAPGPRGEAGGQAEARENG 269
A PG +GE G + G
Sbjct: 949 PA--GPPGEKGEPGDDGPSGAEG 969
Score = 32.3 bits (72), Expect = 0.53
Identities = 36/118 (30%), Positives = 43/118 (36%), Gaps = 22/118 (18%)
Query: 191 AKGQVEA---RRESLDPVQEPGGQAEADGDVPGPRGEA--EGQAEAKGD--------APG 237
AKG+ A + ES P + +PG RG G A A+G+ PG
Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357
Query: 238 PRGEAGGQ-------AEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQND 288
P G AGG A+ E G RG G Q E G PG S N D
Sbjct: 358 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGASGNPGTD 413
Score = 32.0 bits (71), Expect = 0.69
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 14/71 (19%)
Query: 208 PGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARE 267
P A A G PGP+G+ + K D GP+G PGP+G AG Q +
Sbjct: 90 PTDLATASGQ-PGPKGQKGEPGDIK-DIVGPKGP-----------PGPQGPAGEQGPRGD 136
Query: 268 NGEEA-KELPG 277
G++ K PG
Sbjct: 137 RGDKGEKGAPG 147
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/139 (33%), Positives = 58/139 (41%), Gaps = 16/139 (11%)
Query: 142 FPGVALRHVEPGEPLAPSPQ----EPQAVGRQSLL--AKSPLRQETQEAPGP--REEAKG 193
FPG+ EPG+ AP P VG L A P R+ + A GP R+ A G
Sbjct: 925 FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 984
Query: 194 QVEARRESLDPVQEPGGQAEADGDVP-GPRGEAEGQAEAKGDAP-GPRGEAGGQAEAEGD 251
V+ R V PG P GP G+ + EA P GP G AG +
Sbjct: 985 -VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG----- 1038
Query: 252 APGPRGEAGGQAEARENGE 270
GP+G G + EA E GE
Sbjct: 1039 IQGPQGPRGDKGEAGEPGE 1057
Score = 41.6 bits (96), Expect = 9e-04
Identities = 50/159 (31%), Positives = 59/159 (37%), Gaps = 39/159 (24%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA 191
G P FPG A R PG P P P PGP +
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP---------------------PGPSGK- 856
Query: 192 KGQVEARRESLDP--VQEPGGQAEADGDVPGPRGEA--EGQAEAKGDAPGPRGEAG---- 243
G AR +S P EPG Q A PG +GE +G + A+G PGP+G AG
Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGDDGPSGAEG-PPGPQGLAGQRGI 913
Query: 244 ----GQAEAEG--DAPGPRGEAGGQAEARENGEEAKELP 276
GQ G PGP GE G Q +G+ P
Sbjct: 914 VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/100 (37%), Positives = 45/100 (45%), Gaps = 17/100 (17%)
Query: 185 PGPREEAKGQ-VEARRESLDPVQEPG--GQAEADGDVPGPRGEAEGQAEAKGDA--PGPR 239
PGP A + R P G G ADG PG +GE +G+A KGDA PGP+
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ-PGAKGE-QGEAGQKGDAGAPGPQ 797
Query: 240 GEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGET 279
G +G APGP+G G G A+ PG T
Sbjct: 798 GPSG--------APGPQGPTGVTGPKGARG--AQGPPGAT 827
Score = 38.5 bits (88), Expect = 0.007
Identities = 33/100 (33%), Positives = 46/100 (46%), Gaps = 24/100 (24%)
Query: 163 PQAVGRQSLLAKSPLRQETQEA--PGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPG 220
PQ + +LL + LR + Q+ PGP+ + KG+ ++ + P PG Q G
Sbjct: 7 PQTLVLLTLLVAAVLRCQGQDVRQPGPKGQ-KGEPGDIKDIVGPKGPPGPQ--------G 57
Query: 221 PRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAG 260
P GE GPRG+ G + E APGPRG G
Sbjct: 58 PAGEQ-----------GPRGDRGDKGEK--GAPGPRGRDG 84
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 23/141 (16%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAV----GRQSLLAKSPLRQETQE-----APGPREEAKG 193
PGV PGE +P P P+ + GR + R + PGP A G
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295
Query: 194 QVEARRESLDPVQEPGGQAEADGDVPGPRGE-----AEGQAEAKGD-----APGPRGEAG 243
P G +G GPRGE + G A A G+ PG +G AG
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEG-AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG 354
Query: 244 --GQAEAEGDAPGPRGEAGGQ 262
G A A G PGPRG G Q
Sbjct: 355 APGIAGAPG-FPGPRGPPGPQ 374
Score = 36.6 bits (83), Expect = 0.028
Identities = 37/128 (28%), Positives = 48/128 (37%), Gaps = 29/128 (22%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
EPGEP P P+ PGP + EA + + P G
Sbjct: 160 EPGEPGVSGPMGPRG------------------PPGPPGKPGDDGEAGKPGKAGERGPPG 201
Query: 211 QAEADG-----DVPGPRGEA--EGQAEAKGDA--PGPRGEAGGQAEAEGDAPGPRGEAGG 261
A G +PG +G G AKG+A PG +GE+G + E +PGP G G
Sbjct: 202 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESG--SPGENGSPGPMGPRGL 259
Query: 262 QAEARENG 269
E G
Sbjct: 260 PGERGRTG 267
Score = 36.6 bits (83), Expect = 0.028
Identities = 44/147 (29%), Positives = 54/147 (36%), Gaps = 21/147 (14%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA 191
GL+ P FPG E G P A Q P+ L +P + A GP
Sbjct: 624 GLVGPRGERGFPG------ERGSPGAQGLQGPRG------LPGTPGTDGPKGASGPAGPP 671
Query: 192 KGQVEARRESLDPVQEPGGQAEADGD-----VPGPRGEAEGQAEAKG--DAPGPRGEAGG 244
Q + + + G A GD GP G A G+ +G GP G AG
Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGA 730
Query: 245 QAE-AEGDAPGPRGEAGGQAEARENGE 270
E E PGP G AG + E GE
Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGE 757
Score = 35.8 bits (81), Expect = 0.048
Identities = 45/136 (33%), Positives = 54/136 (39%), Gaps = 15/136 (11%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG R EPG P P P P L + Q A G E+A G L
Sbjct: 77 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN---FAAQMAGGFDEKAGGA------QL 127
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAG--GQAEAEGDAPGPRGEAG 260
+Q P G G PGP G A G +G+ PG GE G G G PGP G+ G
Sbjct: 128 GVMQGPMGPMGPRGP-PGPAG-APGPQGFQGN-PGEPGEPGVSGPMGPRGP-PGPPGKPG 183
Query: 261 GQAEARENGEEAKELP 276
EA + G+ + P
Sbjct: 184 DDGEAGKPGKAGERGP 199
Score = 35.8 bits (81), Expect = 0.048
Identities = 46/159 (28%), Positives = 61/159 (38%), Gaps = 26/159 (16%)
Query: 151 EPGEPLAPSPQE----------PQAVGRQSL--LAKSPLRQETQEAPGPREEAKGQVEAR 198
EPG P +P P P A G +A +P + PGP + A G + +
Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QGATGPLGPK 383
Query: 199 RESLDP-------VQEPGGQAEADGD--VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAE 249
++ +P Q P G+ G PGP GE EG+ A+G+ PG G G E
Sbjct: 384 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE-EGKRGARGE-PGGVGPIGPPGER- 440
Query: 250 GDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQND 288
APG RG G A G + P K D
Sbjct: 441 -GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGD 478
Score = 35.8 bits (81), Expect = 0.048
Identities = 48/173 (27%), Positives = 64/173 (36%), Gaps = 26/173 (15%)
Query: 132 GLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPG----- 186
GL PA PG + G A P PQ + Q + P ++ + PG
Sbjct: 876 GLQGPA---GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932
Query: 187 --PREEAKGQVEARRESLDPVQEPG-----GQAEADGD--VPGPRGEAEGQAEAKGDAPG 237
P ++ R PV PG G+ +G GP G +G A KGD
Sbjct: 933 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGR-DGAAGVKGD--- 988
Query: 238 PRGEAG--GQAEAEGD--APGPRGEAGGQAEARENGEEAKELPGETLESKNTQ 286
RGE G G A G +PGP G G Q + E G + P ++ Q
Sbjct: 989 -RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040
Score = 33.9 bits (76), Expect = 0.18
Identities = 42/128 (32%), Positives = 49/128 (38%), Gaps = 31/128 (24%)
Query: 152 PGEPLAPSPQ----EPQAVGRQSLLAKS--PLRQETQEAPGPREEAKGQVEARRESLDPV 205
PGEP P + P G Q + S P PGP + A+GQ
Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-QGARGQ----------- 529
Query: 206 QEPGGQAEADGDVPGPRGE--AEGQAEAKG--DAPGPRGEAGGQAEAEGDAPGPRGEAGG 261
PG PGP+G G+A KG APG RG G + E A GP G AG
Sbjct: 530 --PGVMG-----FPGPKGANGEPGKAGEKGLPGAPGLRGLPG--KDGETGAAGPPGPAGP 580
Query: 262 QAEARENG 269
E E G
Sbjct: 581 AGERGEQG 588
Score = 33.9 bits (76), Expect = 0.18
Identities = 43/143 (30%), Positives = 52/143 (36%), Gaps = 19/143 (13%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA--KGQVEARRE 200
PG A PG P + Q Q A +P Q APGP+ G AR
Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820
Query: 201 SLDP-----------VQEPGGQAE-ADGDVPGPRGEAEGQAEAKGDA--PGPRGEAGGQA 246
P V PG PGP G+ +G A+GD+ PG GE G Q
Sbjct: 821 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK-DGPKGARGDSGPPGRAGEPGLQG 879
Query: 247 EAEGDAPGPRGEAGGQAEARENG 269
A PG +GE G + G
Sbjct: 880 PA--GPPGEKGEPGDDGPSGAEG 900
Score = 32.3 bits (72), Expect = 0.53
Identities = 36/118 (30%), Positives = 43/118 (36%), Gaps = 22/118 (18%)
Query: 191 AKGQVEA---RRESLDPVQEPGGQAEADGDVPGPRGEA--EGQAEAKGD--------APG 237
AKG+ A + ES P + +PG RG G A A+G+ PG
Sbjct: 229 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 288
Query: 238 PRGEAGGQ-------AEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQND 288
P G AGG A+ E G RG G Q E G PG S N D
Sbjct: 289 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGASGNPGTD 344
Score = 30.8 bits (68), Expect = 1.5
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 13/60 (21%)
Query: 219 PGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEA-KELPG 277
PGP+G+ + K D GP+G PGP+G AG Q + G++ K PG
Sbjct: 31 PGPKGQKGEPGDIK-DIVGPKGP-----------PGPQGPAGEQGPRGDRGDKGEKGAPG 78
>gi|21281683 multiple coagulation factor deficiency 2 [Homo sapiens]
Length = 146
Score = 45.8 bits (107), Expect = 5e-05
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Query: 68 LSREQVLLYLFALHDYDQSGQLDGLELLSMLT-AALAPGAANSP--TTNPVILIVDKVLE 124
+S +++ L+ F +HDYD + LDGLEL + +T G+ +P + + +I I+D VL
Sbjct: 67 MSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLR 126
Query: 125 TQDLNGDGLMTPAE 138
D N DG + AE
Sbjct: 127 DDDKNNDGYIDYAE 140
>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
Length = 540
Score = 45.4 bits (106), Expect = 6e-05
Identities = 53/171 (30%), Positives = 67/171 (39%), Gaps = 35/171 (20%)
Query: 136 PAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEA-PGPREE--AK 192
P+E + PG R +PG P P P GR PL + + PGP+ E A
Sbjct: 113 PSECVCPPGPPGRRGKPGRRGDPGP--PGQSGRDGY--PGPLGLDGKPGLPGPKGEKGAP 168
Query: 193 GQVEARRE-----SLDPVQEPG--GQAEADGDV--PGPRGEAEGQAEAKGDA-------- 235
G R + + P PG G GD GPRG A+G A KG+
Sbjct: 169 GDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRG-AQGPAGPKGEPGQDGEMGP 227
Query: 236 ---PGPRGEAGGQAEAEGDA-------PGPRGEAGGQAEARENGEEAKELP 276
PGP+GE G + D PGP+GE G ENG + P
Sbjct: 228 KGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGP 278
Score = 41.6 bits (96), Expect = 9e-04
Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 33/129 (25%)
Query: 150 VEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPG 209
VEPG P P P P +G Q + + P + AKG+ A E + P
Sbjct: 409 VEPGPPGPPGPPGP--MGLQGI-----------QGPKGLDGAKGEKGASGE-----RGPS 450
Query: 210 GQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDA-PGPRGEAGGQAEAREN 268
G +PGP G PG +GE G E D PGPRGE G ++E E
Sbjct: 451 G-------LPGPVGPP-----GLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEK 498
Query: 269 GEEAKELPG 277
GE + +PG
Sbjct: 499 GE--RGVPG 505
Score = 37.4 bits (85), Expect = 0.016
Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 22/150 (14%)
Query: 131 DGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPR-E 189
DG P L PG+ GE AP P+ Q A P A GP +
Sbjct: 144 DGYPGPLGLDGKPGLP---GPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGD 200
Query: 190 EAKGQVEARRESLDPVQEPGGQAE-ADGDVPGPRGEAEGQAEAKGD--------APGPRG 240
K + P EPG E PGP+GE G KGD PGP+G
Sbjct: 201 TGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEP-GVPGKKGDDGTPSQPGPPGPKG 259
Query: 241 EAGGQAEAEGDAPGPRGEAGGQAEARENGE 270
E G GPRGE G GE
Sbjct: 260 EPGSM--------GPRGENGVDGAPGPKGE 281
Score = 34.7 bits (78), Expect = 0.11
Identities = 33/91 (36%), Positives = 40/91 (43%), Gaps = 19/91 (20%)
Query: 204 PVQEPG--GQAEADGDV-----PGPRGEAEGQAEAKGD-----APGPRGEAG-----GQA 246
P EPG G+ DG PGP+GE G +G+ APGP+GE G G A
Sbjct: 233 PKGEPGVPGKKGDDGTPSQPGPPGPKGEP-GSMGPRGENGVDGAPGPKGEPGHRGTDGAA 291
Query: 247 EAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
G APG +GE G +G L G
Sbjct: 292 GPRG-APGLKGEQGDTVVIDYDGRILDALKG 321
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 45.1 bits (105), Expect = 8e-05
Identities = 48/139 (34%), Positives = 62/139 (44%), Gaps = 25/139 (17%)
Query: 160 PQEPQAVGRQSLLAKSPLRQET-----------QEAPGP----REEAKGQVEARRESLDP 204
P EP GR+ A++P E +AP P EEA+ V S P
Sbjct: 1164 PWEPPREGREESEAEAPRGAEEAFPAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPSP 1223
Query: 205 VQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGE--AGGQ 262
P + D PGP+ +AEG EA G R EA G+ E+E + G GE G Q
Sbjct: 1224 TYTPILE-----DAPGPQPQAEGSQEASWGVQG-RAEALGKVESEQEELG-SGEIPEGPQ 1276
Query: 263 AEARENGEEAKELP-GETL 280
E E+ EE++E GETL
Sbjct: 1277 EEGEESREESEEDELGETL 1295
>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
sapiens]
Length = 584
Score = 44.3 bits (103), Expect = 1e-04
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 11/149 (7%)
Query: 127 DLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPG 186
+L DG+ + E + ++ EP P A P+A R LA +P R++ +P
Sbjct: 332 ELLTDGVRSFREPAPAEALPQQYPEPA-PAALCGPPPRAPSRN--LAPTPRRRKA--SPE 386
Query: 187 PREEAKGQVEARRESLDPVQEPGG--QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGG 244
P EA G++ + PGG AE G VP P + AEA G +P G GG
Sbjct: 387 PEGEAAGKMTTEEQQQRHWVAPGGPYSAETPG-VPSPIAALKNVAEALGHSPKDPGGGGG 445
Query: 245 QAEAEGDAPGPRGEAGGQAEAR---ENGE 270
A G +P A + R NGE
Sbjct: 446 PVRAGGASPAASSTAQPPTQHRLVARNGE 474
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 19/136 (13%)
Query: 152 PGEPLAPSPQE---PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEP 208
PG P P P P G Q + P Q PGP+ E + + + V +P
Sbjct: 158 PGPPGLPGPSGITIPGKPGAQGV----PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQP 213
Query: 209 G-----GQAEADGD--VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGG 261
G GQ A G +PGP G + + APG +GE+G PGPRGE G
Sbjct: 214 GLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPG-----VPGPRGEPGA 268
Query: 262 QAEARENGEEAKELPG 277
G + +PG
Sbjct: 269 VGPKGPPGVDGVGVPG 284
Score = 41.6 bits (96), Expect = 9e-04
Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 15/137 (10%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG+ EPGE P Q PQ +G L S + PGP+ EA +
Sbjct: 333 PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGI 392
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQ 262
Q P G A G VPG RG A GP G G + E PG G GG
Sbjct: 393 RGDQGPSGLAGKPG-VPGERG--------LPGAHGPPGPTGPKGE-----PGFTGRPGGP 438
Query: 263 AEARENGEEAK-ELPGE 278
A G++ LPG+
Sbjct: 439 GVAGALGQKGDLGLPGQ 455
Score = 36.6 bits (83), Expect = 0.028
Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQE--APGPREEAKGQVEARRE 200
PG + PG P P P G L + E+ PGPR E
Sbjct: 216 PGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPP 275
Query: 201 SLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGE-- 258
+D V PG +PGP+G + + E GP G G PGP+G+
Sbjct: 276 GVDGVGVPGAAG-----LPGPQGPSGAKGEP--GTRGPPGLIGPTGYGMPGLPGPKGDRG 328
Query: 259 -------AGGQAEARENGEEAKELP 276
G + E E+GE ++ P
Sbjct: 329 PAGVPGLLGDRGEPGEDGEPGEQGP 353
Score = 31.6 bits (70), Expect = 0.90
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 207 EPGGQAEADGDVPGPRG-EAEGQAEAKGDAPGPRGEAG----GQ-----AEAEGDAPGPR 256
+PG Q VPGP G + E + + PG RG G GQ A +G APGP
Sbjct: 174 KPGAQG-----VPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPP 228
Query: 257 GEAGGQAEARENGEEAKELPGETLES 282
G G + + PG+ ES
Sbjct: 229 GLPGPAGLGKPGLDGLPGAPGDKGES 254
Score = 30.0 bits (66), Expect = 2.6
Identities = 42/158 (26%), Positives = 50/158 (31%), Gaps = 15/158 (9%)
Query: 136 PAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEA--KG 193
P+ L PGV PG P P P+ G + P A G + + G
Sbjct: 398 PSGLAGKPGVPGERGLPGAHGPPGPTGPK--GEPGFTGR-PGGPGVAGALGQKGDLGLPG 454
Query: 194 QVEARRESLDP-VQEPGGQAEADG--------DVPGPRGEAEGQAEAKGDAPGPRGEAGG 244
Q R S P +Q P G G +PGP GE GP G G
Sbjct: 455 QPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGS 514
Query: 245 QA-EAEGDAPGPRGEAGGQAEARENGEEAKELPGETLE 281
PGP G G E G LP +E
Sbjct: 515 PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVE 552
>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
sapiens]
Length = 828
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 14/76 (18%)
Query: 207 EPGGQ-AEADGDVPGPRGEAEGQAEAKGDA-------PGPRGEAGGQAEAEGDAPGPRGE 258
EPG Q + D GPRG++ GQ KGD PGPRG G + E PGPRG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDS-GQPGPKGDPGRPGFSYPGPRGAPGEKGE-----PGPRGP 535
Query: 259 AGGQAEARENGEEAKE 274
GG+ + GE ++
Sbjct: 536 EGGRGDFGLKGEPGRK 551
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/142 (33%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG R PGE A + Q S SP + + PGPR KG+ R +
Sbjct: 375 PGRPGRRGPPGEIGAKGSKGYQG---NSGAPGSPGVKGAKGGPGPRGP-KGEPGRRGD-- 428
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDA--PGPRGEAG--GQAEAEGDA--PGPR 256
PG + D GP+GE KGD GPRG AG G A+GD PGPR
Sbjct: 429 -----PGTKGSPGSD--GPKGE-------KGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
Query: 257 GEAGGQAEARENGEEAKELPGE 278
G G E + G PG+
Sbjct: 475 GPQGALGEPGKQGSRGD--PGD 494
Score = 33.5 bits (75), Expect = 0.24
Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)
Query: 160 PQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVP 219
P EP GRQ P + PGP+ + E D + G A +G
Sbjct: 276 PGEPGQKGRQG----DPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG-TD 330
Query: 220 GPRGEAE--GQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
G +G+ G KGD PG RG G EA +PG RG+ GG+ + G PG
Sbjct: 331 GQKGKLGRIGPPGCKGD-PGNRGPDGYPGEA--GSPGERGDQGGKGDPGRPGRRGP--PG 385
Query: 278 E 278
E
Sbjct: 386 E 386
>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
sapiens]
Length = 918
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 14/76 (18%)
Query: 207 EPGGQ-AEADGDVPGPRGEAEGQAEAKGDA-------PGPRGEAGGQAEAEGDAPGPRGE 258
EPG Q + D GPRG++ GQ KGD PGPRG G + E PGPRG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDS-GQPGPKGDPGRPGFSYPGPRGAPGEKGE-----PGPRGP 535
Query: 259 AGGQAEARENGEEAKE 274
GG+ + GE ++
Sbjct: 536 EGGRGDFGLKGEPGRK 551
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/142 (33%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG R PGE A + Q S SP + + PGPR KG+ R +
Sbjct: 375 PGRPGRRGPPGEIGAKGSKGYQG---NSGAPGSPGVKGAKGGPGPRGP-KGEPGRRGD-- 428
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDA--PGPRGEAG--GQAEAEGDA--PGPR 256
PG + D GP+GE KGD GPRG AG G A+GD PGPR
Sbjct: 429 -----PGTKGSPGSD--GPKGE-------KGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
Query: 257 GEAGGQAEARENGEEAKELPGE 278
G G E + G PG+
Sbjct: 475 GPQGALGEPGKQGSRGD--PGD 494
Score = 33.5 bits (75), Expect = 0.24
Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)
Query: 160 PQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVP 219
P EP GRQ P + PGP+ + E D + G A +G
Sbjct: 276 PGEPGQKGRQG----DPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG-TD 330
Query: 220 GPRGEAE--GQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
G +G+ G KGD PG RG G EA +PG RG+ GG+ + G PG
Sbjct: 331 GQKGKLGRIGPPGCKGD-PGNRGPDGYPGEA--GSPGERGDQGGKGDPGRPGRRGP--PG 385
Query: 278 E 278
E
Sbjct: 386 E 386
>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
sapiens]
Length = 1019
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 14/76 (18%)
Query: 207 EPGGQ-AEADGDVPGPRGEAEGQAEAKGDA-------PGPRGEAGGQAEAEGDAPGPRGE 258
EPG Q + D GPRG++ GQ KGD PGPRG G + E PGPRG
Sbjct: 482 EPGKQGSRGDPGDAGPRGDS-GQPGPKGDPGRPGFSYPGPRGAPGEKGE-----PGPRGP 535
Query: 259 AGGQAEARENGEEAKE 274
GG+ + GE ++
Sbjct: 536 EGGRGDFGLKGEPGRK 551
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/142 (33%), Positives = 58/142 (40%), Gaps = 28/142 (19%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG R PGE A + Q S SP + + PGPR KG+ R +
Sbjct: 375 PGRPGRRGPPGEIGAKGSKGYQG---NSGAPGSPGVKGAKGGPGPRGP-KGEPGRRGD-- 428
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDA--PGPRGEAG--GQAEAEGDA--PGPR 256
PG + D GP+GE KGD GPRG AG G A+GD PGPR
Sbjct: 429 -----PGTKGSPGSD--GPKGE-------KGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
Query: 257 GEAGGQAEARENGEEAKELPGE 278
G G E + G PG+
Sbjct: 475 GPQGALGEPGKQGSRGD--PGD 494
Score = 33.5 bits (75), Expect = 0.24
Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)
Query: 160 PQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVP 219
P EP GRQ P + PGP+ + E D + G A +G
Sbjct: 276 PGEPGQKGRQG----DPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNG-TD 330
Query: 220 GPRGEAE--GQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
G +G+ G KGD PG RG G EA +PG RG+ GG+ + G PG
Sbjct: 331 GQKGKLGRIGPPGCKGD-PGNRGPDGYPGEA--GSPGERGDQGGKGDPGRPGRRGP--PG 385
Query: 278 E 278
E
Sbjct: 386 E 386
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/127 (32%), Positives = 49/127 (38%), Gaps = 21/127 (16%)
Query: 152 PGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQ 211
P P P P PQ R L E + GPR G++ +R S PG
Sbjct: 41 PAPPPGPGPAPPQHPPRAEALPP-----EAADEGGPR----GRLRSRDSSCGRPGTPGAA 91
Query: 212 AEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGG-------QAEAEGDAPGP-RGEAGGQA 263
+ A G P GE G+ E + GP G A G + A G APGP E G
Sbjct: 92 STAKGS---PNGEC-GRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSE 147
Query: 264 EARENGE 270
EA GE
Sbjct: 148 EAGPAGE 154
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/137 (31%), Positives = 60/137 (43%), Gaps = 14/137 (10%)
Query: 158 PSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLD-PVQEPG---GQAE 213
P EPQA + AK + Q+A G EE +G+ +A + P EP G AE
Sbjct: 37 PKESEPQAAAEPAE-AKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAE 95
Query: 214 ADGDVPGPRGEAEGQAEAKGDAPGPR--GEAGGQAEAEGDAPGPRGEAGGQAEARENGEE 271
A + P +A Q +A APGP GEA AEA A G+ ++E GE
Sbjct: 96 AKAEPP----KAPEQEQA---APGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEP 148
Query: 272 AKELPGETLESKNTQND 288
K ++ T++D
Sbjct: 149 KKTEAPAAPAAQETKSD 165
Score = 33.9 bits (76), Expect = 0.18
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 174 KSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQ---AE 230
K+ + + E EE + + + +P + G+ + D D G E EG+ A
Sbjct: 18 KAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAA 77
Query: 231 AKGDAPGP---RGEAGGQAEAEGD--------APGPRGEAGGQAEARENGEEAKELPGET 279
AK +AP + E +A+AE APGP AGG+A EA P E+
Sbjct: 78 AKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGP--AAGGEA---PKAAEAAAAPAES 132
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 43.1 bits (100), Expect = 3e-04
Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG+A E GEP P + A G++ L+ R + PGP+ + + E +
Sbjct: 2652 PGLAGHKGEMGEPGVPG--QSGAPGKEGLIGPKGDRGFDGQ-PGPKGDQGEKGERGTPGI 2708
Query: 203 DPVQEPGGQAEADGDVPGPRGEA-----EGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRG 257
P G + G PGP G EG KG+ GP GE A APG RG
Sbjct: 2709 GGFPGPSGNDGSAGP-PGPPGSVGPRGPEGLQGQKGER-GPPGERVVGAPGVPGAPGERG 2766
Query: 258 EAGGQAEARENGEEAK 273
E G A GE+ +
Sbjct: 2767 EQGRPGPAGPRGEKGE 2782
Score = 41.6 bits (96), Expect = 9e-04
Identities = 51/142 (35%), Positives = 57/142 (40%), Gaps = 31/142 (21%)
Query: 142 FPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRES 201
FPG R PG A +P P A G L SP PGPR + R
Sbjct: 1300 FPGADGRPGSPGR--AGNPGTPGAPG----LKGSP------GLPGPRGDP-----GERGP 1342
Query: 202 LDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAG- 260
P EPG A G V G GE G KGD PGP G G + GD PGPRG G
Sbjct: 1343 RGPKGEPG----APGQVIG--GEGPGLPGRKGD-PGPSGPPGPRGPL-GD-PGPRGPPGL 1393
Query: 261 ----GQAEARENGEEAKELPGE 278
+ + + GE PGE
Sbjct: 1394 PGTAMKGDKGDRGERGPPGPGE 1415
Score = 41.2 bits (95), Expect = 0.001
Identities = 52/172 (30%), Positives = 66/172 (38%), Gaps = 34/172 (19%)
Query: 130 GDGLMTPAELINFPGVALRHVEPGEPLAPSPQ-------------EPQAVGRQSLLAK-- 174
G GL P + PG PG PQ +P A GR K
Sbjct: 2216 GRGLTGPTGAVGLPG------PPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDG 2269
Query: 175 ---SPLRQETQEAPGP--REEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQA 229
SP + PGP + G A +++ V PG + E G G G+ G+
Sbjct: 2270 DRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAV--VGLPGAKGEK-GAPGGLAGDLVGEP 2326
Query: 230 EAKGD--APGPRGEAG--GQAEAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
AKGD PGPRGE G G+A GD PG G+ G G+ +PG
Sbjct: 2327 GAKGDRGLPGPRGEKGEAGRAGEPGD-PGEDGQKGAPGPKGFKGDPGVGVPG 2377
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/146 (32%), Positives = 57/146 (39%), Gaps = 20/146 (13%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAP-GPREEAKGQVEARRES 201
PG R E GEP P +P VG P ++ P GPR Q E
Sbjct: 1524 PGPTGRQGEKGEPGRPG--DPAVVGPA---VAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578
Query: 202 LDPVQEPGGQAEADGDVPGPRGEA--EGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEA 259
L +PG + + PG RG G+A GD+ GP GE G PGP G
Sbjct: 1579 LVLPGDPGPKGD-----PGDRGPIGLTGRAGPPGDS-GPPGEKGDPGRP--GPPGPVGPR 1630
Query: 260 GGQAEARENGEEAKE----LPGETLE 281
G E E G+E LPG+ E
Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGE 1656
Score = 40.8 bits (94), Expect = 0.001
Identities = 28/68 (41%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 203 DPVQEPGGQAEADGDVPGPRGEA--EGQAEAKGD--------APGPRGEAGGQAEAEGDA 252
D V EPG A+ D +PGPRGE G+A GD APGP+G G +
Sbjct: 2321 DLVGEPG--AKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378
Query: 253 PGPRGEAG 260
PGP G G
Sbjct: 2379 PGPPGPPG 2386
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/136 (33%), Positives = 51/136 (37%), Gaps = 25/136 (18%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG + PGEP P L SP Q PG + E KG E L
Sbjct: 1411 PGPGEGGIAPGEPGLPG------------LPGSPGPQGPVGPPGKKGE-KGDSEDGAPGL 1457
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDA--PGPRGEAGGQAEAEGDAPGPRGEAG 260
+PG E GPRG G KGD PGP GEAG + E PGP G G
Sbjct: 1458 PG--QPGSPGEQ-----GPRGPP-GAIGPKGDRGFPGPLGEAGEKGER--GPPGPAGSRG 1507
Query: 261 GQAEARENGEEAKELP 276
A G + E P
Sbjct: 1508 LPGVAGRPGAKGPEGP 1523
Score = 37.0 bits (84), Expect = 0.021
Identities = 36/134 (26%), Positives = 46/134 (34%), Gaps = 30/134 (22%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPR-------EEAKGQV 195
PG+ R +PG P P+ P PGPR KG
Sbjct: 1361 PGLPGRKGDPGPSGPPGPRGPLG------------------DPGPRGPPGLPGTAMKGDK 1402
Query: 196 EARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGP 255
R E P GG A + +PG G Q GP G+ G + ++E APG
Sbjct: 1403 GDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPV-----GPPGKKGEKGDSEDGAPGL 1457
Query: 256 RGEAGGQAEARENG 269
G+ G E G
Sbjct: 1458 PGQPGSPGEQGPRG 1471
Score = 37.0 bits (84), Expect = 0.021
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 186 GPREEAKGQVEARRESLDPVQEPGGQA-EADGDVPGPRGEAEGQAEAKGDAPGPRGEAGG 244
GP+ ++ Q +E P+ PG + + D PGP+G G A + PGP G AG
Sbjct: 1979 GPKGDSGEQGPPGKEG--PIGFPGERGLKGDRGDPGPQGPP-GLALGERGPPGPSGLAGE 2035
Query: 245 QAEAEGDAPGPRGEAGGQAEARENGEEAK 273
+ PG G AGG EA GE +
Sbjct: 2036 PGKP--GIPGLPGRAGGVGEAGRPGERGE 2062
Score = 37.0 bits (84), Expect = 0.021
Identities = 45/126 (35%), Positives = 53/126 (42%), Gaps = 10/126 (7%)
Query: 152 PGEPLAPSPQEPQAVGRQSLLA-KSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
PG PL P P P +VG K PGPR E +G+ R E P QE G
Sbjct: 2436 PG-PLGP-PGPPGSVGPPGASGLKGDKGDPGVGLPGPRGE-RGEPGIRGEDGRPGQE--G 2490
Query: 211 QAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGE 270
G PG RGE G+ G A G +G+ G A G PGPRG G E G
Sbjct: 2491 PRGLTGP-PGSRGE-RGEKGDVGSA-GLKGDKGDSAVILGP-PGPRGAKGDMGERGPRGL 2546
Query: 271 EAKELP 276
+ + P
Sbjct: 2547 DGDKGP 2552
Score = 36.2 bits (82), Expect = 0.036
Identities = 77/315 (24%), Positives = 114/315 (36%), Gaps = 80/315 (25%)
Query: 9 LILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQP--GQEQLGLLQSYLKGLGRTEVQLE 66
L+L L P G A + G+ + + P+P P G LG++
Sbjct: 1079 LVLALGPLGPQAVQVGL------LSYSHRPSPLFPLNGSHDLGII--------------- 1117
Query: 67 HLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVDKVLETQ 126
L R + + Y+ D SG G +++ LAP A P ++++ L +
Sbjct: 1118 -LQRIRDMPYM------DPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVL---LVDE 1167
Query: 127 DLNGDGLMTPAELINFPGV-------------ALRHVEPGEPLAPS-------PQEPQAV 166
L GD + +P G+ LR + PG + P QAV
Sbjct: 1168 PLRGD-IFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAV 1226
Query: 167 -GRQSLLAKSPLRQETQEAPGPREEAKGQVE-----ARRESLDPVQEPGGQAEADGDVPG 220
G + L ++ + + P P KGQ R + P +PG PG
Sbjct: 1227 SGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGA--PG 1284
Query: 221 PRGEAEGQAEAKGDA--------PGPRGEAG--GQAEAEG-----DAPGPRGEAGGQAEA 265
P+G G A AKG+ PG G AG G A G PGPRG+ G +
Sbjct: 1285 PQGPP-GSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPR 1343
Query: 266 RENGEEAKELPGETL 280
GE PG+ +
Sbjct: 1344 GPKGEPG--APGQVI 1356
Score = 35.8 bits (81), Expect = 0.048
Identities = 32/96 (33%), Positives = 40/96 (41%), Gaps = 16/96 (16%)
Query: 185 PGPR-EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAG 243
PGPR ++ + R P +PG Q GPRG G GD PGP G G
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQ--------GPRGPP-GPVGGHGD-PGPPGAPG 2192
Query: 244 GQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGET 279
A GP+G +G + E E G + L G T
Sbjct: 2193 LAGPA-----GPQGPSGLKGEPGETGPPGRGLTGPT 2223
Score = 35.4 bits (80), Expect = 0.062
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 11/102 (10%)
Query: 185 PGPREEAKGQVEARRESLDPVQEPG-----GQAEADG--DVPGPRGE--AEGQAEAKGDA 235
PG RE+ + + P +PG G+ +G PGP+G+ G A KGD
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR 1772
Query: 236 PGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPG 277
P + + + A GP G G +A + G + LPG
Sbjct: 1773 GPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDG--LPG 1812
Score = 34.3 bits (77), Expect = 0.14
Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 17/134 (12%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
+PG P P P P+ GR + + + P + + + PV E G
Sbjct: 1617 DPGRPGPPGPVGPR--GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD 1674
Query: 211 QAEADGDVPGPRGEAEGQAEAKGDA--PGPRGEAG-----GQAEAEGDAPGPRGEAGGQA 263
Q + D R + G + KGD PGP G G G E PG RG+ G +
Sbjct: 1675 QGDPGED---GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG 1731
Query: 264 EARENGEEAKELPG 277
+ G LPG
Sbjct: 1732 PKGDPG-----LPG 1740
Score = 33.5 bits (75), Expect = 0.24
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 20/86 (23%)
Query: 210 GQAEADGDV--PGPRGEAEGQAEAKG--------DAPGPRGEAG--GQAEAEGDA----- 252
GQ G++ PGP GE G A G PGP G G G + +GD
Sbjct: 2407 GQTGPRGEMGQPGPSGE-RGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV 2465
Query: 253 --PGPRGEAGGQAEARENGEEAKELP 276
PGPRGE G E+G +E P
Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGP 2491
Score = 32.0 bits (71), Expect = 0.69
Identities = 40/151 (26%), Positives = 53/151 (35%), Gaps = 23/151 (15%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAP-GPREE-----AKGQ-- 194
PG + + GEP P P K QE P GP+ + A G+
Sbjct: 1687 PGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746
Query: 195 VEARRESLDPVQEPG--GQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA---- 248
+E R P +PG G A GD P + + K A GP G G +A
Sbjct: 1747 IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG 1806
Query: 249 ---------EGDAPGPRGEAGGQAEARENGE 270
E PGP G G + E+G+
Sbjct: 1807 RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837
Score = 31.6 bits (70), Expect = 0.90
Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 23/132 (17%)
Query: 153 GEPLAPSPQEPQAV-GRQSLLAKSPLRQETQEAPGPREEA----KGQVEAR-RESLDPVQ 206
GE P P P + G+ K L + E P E+ KG A RE D
Sbjct: 1815 GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG-- 1872
Query: 207 EPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEAR 266
P G+ A G + GP+G PG G G + PG G G + E
Sbjct: 1873 -PKGERGAPG-ILGPQGP-----------PGLPGPVGPPGQGFPGVPGGTGPKGDRGETG 1919
Query: 267 ENGEEAKELPGE 278
GE+ LPGE
Sbjct: 1920 SKGEQG--LPGE 1929
Score = 31.6 bits (70), Expect = 0.90
Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 140 INFPGVALRHVEPGEPLAPSPQEPQ--AVGRQSLLAKSPLRQETQEA--PGPREEAKGQV 195
I FPG + G+P PQ P A+G + S L E + PG A G
Sbjct: 1996 IGFPGERGLKGDRGDP---GPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052
Query: 196 EARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKG--DAPGPRGEAGGQAEAEGDAP 253
EA R PG + E G RGE +G+ G PGP G G + + P
Sbjct: 2053 EAGR--------PGERGERGEK--GERGE-QGRDGPPGLPGTPGPPGPPGPKVSVDEPGP 2101
Query: 254 ------GPRGEAGGQAEARENGEE 271
GP G G + E NG++
Sbjct: 2102 GLSGEQGPPGLKGAKGEPGSNGDQ 2125
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/131 (31%), Positives = 57/131 (43%), Gaps = 12/131 (9%)
Query: 152 PGEPLAPSPQEPQAV-----GRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQ 206
PG PL+ + V + L +SP R E QE EEAK +ARR S +
Sbjct: 214 PGSPLSSEGAAGEGVRTLGPAEKPPLRRSPSRTEKQEEDRATEEAKNGEKARRSS----E 269
Query: 207 EPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEA- 265
E GQ A +VP + +AE + +P AG +AE E A +GE E
Sbjct: 270 EVDGQHPAQEEVPESPQTSGPEAENRCGSPREEKPAGEEAEME-KATEVKGERVQNEEVG 328
Query: 266 -RENGEEAKEL 275
+ +E K+L
Sbjct: 329 PEHDSQETKKL 339
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 42.7 bits (99), Expect = 4e-04
Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 15/108 (13%)
Query: 178 RQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPG 237
RQ + PGP G +RR++ + + +PGP G EG KG G
Sbjct: 1532 RQGRRGWPGP----PGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDG-LEGSLGLKGPQ-G 1585
Query: 238 PRGEAGGQAEAEG-------DAPGPRGEAGGQAEARENGEEAKELPGE 278
PRGEAG + E G PGP GEAG Q G + + PG+
Sbjct: 1586 PRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGE--PGD 1631
Score = 32.0 bits (71), Expect = 0.69
Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 16/107 (14%)
Query: 186 GPREEA-----KGQVEARRESLDPVQEPGGQAEADGDV--PGPRGEAEGQAEAKGDA--P 236
GPR EA KG V ++ P PGG+A G + G +GE G KG P
Sbjct: 1585 GPRGEAGVKGEKGGVGSKGPQGPP--GPGGEAGNQGRLGSQGNKGEP-GDLGEKGAVGFP 1641
Query: 237 GPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAK----ELPGET 279
GPRG G + G +G G + E+G + + PGET
Sbjct: 1642 GPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGET 1688
>gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]
Length = 1464
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 19/116 (16%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA 248
E A+ +VEA ++ + AE +G+ GP GEA AE G+A P GEA +
Sbjct: 1269 EAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEA---AEPIGEAGQPNGEA---EQP 1322
Query: 249 EGDAPGPRG-----------EAGGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
GDA P G E G+AE E +A E G +E D E+ +
Sbjct: 1323 NGDADEPDGAGIEDPEERAEEPEGKAEEPEG--DADEPDGVGIEDPEEGEDQEIQV 1376
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 19/147 (12%)
Query: 163 PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPR 222
PQ V R L E + A E A+ +VEA + + G AE G+ P
Sbjct: 1257 PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN 1316
Query: 223 GEAEGQAEAKGDAPGPRG-----------EAGGQA-EAEGDAPGPRGEAGGQAEARENGE 270
GEAE + GDA P G E G+A E EGDA P G E E+ E
Sbjct: 1317 GEAE---QPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQE 1373
Query: 271 EAKELP----GETLESKNTQNDFEVHI 293
E P E E+ + F H+
Sbjct: 1374 IQVEEPYYDCHECTETFTSSTAFSEHL 1400
>gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens]
Length = 1588
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 19/116 (16%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA 248
E A+ +VEA ++ + AE +G+ GP GEA AE G+A P GEA +
Sbjct: 1393 EAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEA---AEPIGEAGQPNGEA---EQP 1446
Query: 249 EGDAPGPRG-----------EAGGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
GDA P G E G+AE E +A E G +E D E+ +
Sbjct: 1447 NGDADEPDGAGIEDPEERAEEPEGKAEEPEG--DADEPDGVGIEDPEEGEDQEIQV 1500
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 19/147 (12%)
Query: 163 PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPR 222
PQ V R L E + A E A+ +VEA + + G AE G+ P
Sbjct: 1381 PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN 1440
Query: 223 GEAEGQAEAKGDAPGPRG-----------EAGGQA-EAEGDAPGPRGEAGGQAEARENGE 270
GEAE + GDA P G E G+A E EGDA P G E E+ E
Sbjct: 1441 GEAE---QPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQE 1497
Query: 271 EAKELP----GETLESKNTQNDFEVHI 293
E P E E+ + F H+
Sbjct: 1498 IQVEEPYYDCHECTETFTSSTAFSEHL 1524
>gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens]
Length = 1462
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 19/116 (16%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA 248
E A+ +VEA ++ + AE +G+ GP GEA AE G+A P GEA +
Sbjct: 1267 EAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEA---AEPIGEAGQPNGEA---EQP 1320
Query: 249 EGDAPGPRG-----------EAGGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
GDA P G E G+AE E +A E G +E D E+ +
Sbjct: 1321 NGDADEPDGAGIEDPEERAEEPEGKAEEPEG--DADEPDGVGIEDPEEGEDQEIQV 1374
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 19/147 (12%)
Query: 163 PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPR 222
PQ V R L E + A E A+ +VEA + + G AE G+ P
Sbjct: 1255 PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN 1314
Query: 223 GEAEGQAEAKGDAPGPRG-----------EAGGQA-EAEGDAPGPRGEAGGQAEARENGE 270
GEAE + GDA P G E G+A E EGDA P G E E+ E
Sbjct: 1315 GEAE---QPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQE 1371
Query: 271 EAKELP----GETLESKNTQNDFEVHI 293
E P E E+ + F H+
Sbjct: 1372 IQVEEPYYDCHECTETFTSSTAFSEHL 1398
>gi|226053126 paternally expressed 3 isoform 1 [Homo sapiens]
Length = 1588
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 19/116 (16%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA 248
E A+ +VEA ++ + AE +G+ GP GEA AE G+A P GEA +
Sbjct: 1393 EAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEA---AEPIGEAGQPNGEA---EQP 1446
Query: 249 EGDAPGPRG-----------EAGGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
GDA P G E G+AE E +A E G +E D E+ +
Sbjct: 1447 NGDADEPDGAGIEDPEERAEEPEGKAEEPEG--DADEPDGVGIEDPEEGEDQEIQV 1500
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 19/147 (12%)
Query: 163 PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPR 222
PQ V R L E + A E A+ +VEA + + G AE G+ P
Sbjct: 1381 PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN 1440
Query: 223 GEAEGQAEAKGDAPGPRG-----------EAGGQA-EAEGDAPGPRGEAGGQAEARENGE 270
GEAE + GDA P G E G+A E EGDA P G E E+ E
Sbjct: 1441 GEAE---QPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQE 1497
Query: 271 EAKELP----GETLESKNTQNDFEVHI 293
E P E E+ + F H+
Sbjct: 1498 IQVEEPYYDCHECTETFTSSTAFSEHL 1524
>gi|33354285 paternally expressed 3 isoform 1 [Homo sapiens]
Length = 1588
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 19/116 (16%)
Query: 189 EEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEA 248
E A+ +VEA ++ + AE +G+ GP GEA AE G+A P GEA +
Sbjct: 1393 EAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEA---AEPIGEAGQPNGEA---EQP 1446
Query: 249 EGDAPGPRG-----------EAGGQAEARENGEEAKELPGETLESKNTQNDFEVHI 293
GDA P G E G+AE E +A E G +E D E+ +
Sbjct: 1447 NGDADEPDGAGIEDPEERAEEPEGKAEEPEG--DADEPDGVGIEDPEEGEDQEIQV 1500
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/147 (30%), Positives = 57/147 (38%), Gaps = 19/147 (12%)
Query: 163 PQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPR 222
PQ V R L E + A E A+ +VEA + + G AE G+ P
Sbjct: 1381 PQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPN 1440
Query: 223 GEAEGQAEAKGDAPGPRG-----------EAGGQA-EAEGDAPGPRGEAGGQAEARENGE 270
GEAE + GDA P G E G+A E EGDA P G E E+ E
Sbjct: 1441 GEAE---QPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQE 1497
Query: 271 EAKELP----GETLESKNTQNDFEVHI 293
E P E E+ + F H+
Sbjct: 1498 IQVEEPYYDCHECTETFTSSTAFSEHL 1524
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 42.4 bits (98), Expect = 5e-04
Identities = 38/144 (26%), Positives = 55/144 (38%), Gaps = 8/144 (5%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGG 210
E EP +P+ E +A S + S + E P P E + + R + G
Sbjct: 112 EAAEPGSPTAAEGEAASAAS--STSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGF 169
Query: 211 QAEADGDVPGPRGEAE------GQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAE 264
+ + G GEAE G+ EA G A EAG + + APG AG +
Sbjct: 170 SFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGA 229
Query: 265 ARENGEEAKELPGETLESKNTQND 288
A + +EAK K +D
Sbjct: 230 AGGDPQEAKPQEAAVAPEKPPASD 253
Score = 33.1 bits (74), Expect = 0.31
Identities = 52/219 (23%), Positives = 65/219 (29%), Gaps = 45/219 (20%)
Query: 99 TAALAPGAANSPTTNPVILIVDKVLETQD----LNGDGLMTPAELINFPGVALRHVEPGE 154
TAA AA P V K ++ +NGD AE G G
Sbjct: 8 TAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAE----SGAKEELQANGS 63
Query: 155 PLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEA 214
A +EP A G + + + E A P E VE + EPG A
Sbjct: 64 APAADKEEPAAAGSGAASPSAAEKGEPAAAAAP-EAGASPVEKEAPAEGEAAEPGSPTAA 122
Query: 215 DGDVPGPRGEAEGQAEAKGDAPGPRGEA------------------------------GG 244
+G+ G P P E GG
Sbjct: 123 EGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGG 182
Query: 245 QAEAEGDAPGPRGEAGGQAEA-----RENGEEAKELPGE 278
+AEA G AGG A A +GE+A PGE
Sbjct: 183 EAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQA-AAPGE 220
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 1/104 (0%)
Query: 143 PGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESL 202
PG A P P +P + R + + +E+P P +A+ V R
Sbjct: 1218 PGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVP 1277
Query: 203 DPVQEPGGQAEADGDVPGPRGEAEGQ-AEAKGDAPGPRGEAGGQ 245
+P G G GPRG+ + Q A KG A G G AG +
Sbjct: 1278 PARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGAR 1321
Score = 34.7 bits (78), Expect = 0.11
Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 4/120 (3%)
Query: 152 PGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQ 211
P PLAP +PQA G++ + +E +E EE + + E E + +E
Sbjct: 718 PQVPLAPV--QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE-EEEEEEAAA 774
Query: 212 AEADGDVPGPR-GEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGE 270
A A G+V GPR G + +E D + A+ + ++ G A G E E +
Sbjct: 775 AVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSK 834
Score = 32.0 bits (71), Expect = 0.69
Identities = 30/125 (24%), Positives = 40/125 (32%), Gaps = 22/125 (17%)
Query: 152 PGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQ 211
PG L P GR A+ P + + R +SL + P
Sbjct: 1212 PGRGLGP--------GRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPS 1263
Query: 212 AEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQ---AEAREN 268
+A VP PRG P R + G G GPRG+ Q + R
Sbjct: 1264 HQARPGVPPPRG-----------VPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAG 1312
Query: 269 GEEAK 273
G E +
Sbjct: 1313 GAEGR 1317
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 10/141 (7%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQ---ETQEAPGPREEAKGQVEARRE----SLD 203
E E +EP+A + KSP++ E +E G +EE +GQ E E D
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546
Query: 204 PVQEPGGQAEADGD-VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQ 262
+E G + E + G + E E +AEA+G+ + E + E + + + E
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK--KVEEKSEEVATKEELVAD 604
Query: 263 AEARENGEEAKELPGETLESK 283
A+ + + +P +E K
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEK 625
Score = 39.7 bits (91), Expect = 0.003
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 177 LRQETQEAPGPREEAKGQVEARRESLDPVQEP-GGQAEADGDVPGPRGEAEGQAEAKGDA 235
+++E +EA +EE + EA E + + P A + G + E EGQ E + +
Sbjct: 484 MKEEKKEAAEEKEE---EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 540
Query: 236 PGPRGEAG--GQAEAEGDAPGPRGEAG-GQAEARENGEEAKELPGETLESKNTQ 286
G + + G +E EG + GE G+ EA GEEA+ + +E K+ +
Sbjct: 541 EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594
Score = 31.6 bits (70), Expect = 0.90
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 31/159 (19%)
Query: 162 EPQAVGRQSLLAKSPLRQETQEAPGPREE--AKGQVEARRESLDPVQEPGGQAEADGDVP 219
E +A G ++ + +E E +EE A +VE ++ PV P E G P
Sbjct: 572 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV--PKSPVEEKGKSP 629
Query: 220 GPRGEAE---------GQAEAKGDAPGPRG--EAGGQA-------EAEGDAPGP------ 255
P+ E E KG +P P+ E G++ E + +P P
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Query: 256 ---RGEAGGQAEARENGEEAKELPGETLESKNTQNDFEV 291
+ E G + E +E KE P E K + +V
Sbjct: 690 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 728
Score = 30.4 bits (67), Expect = 2.0
Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 195 VEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPG 254
V + E + +E + EA+ + + ++ K AP + E G + E EG
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAK-----KSPVKATAPEVKEEEGEKEEEEGQEEE 536
Query: 255 PRGEAGGQAEARENGEEAKELPGETLESKNTQNDFE 290
+ G +++ E G KE E E + + + E
Sbjct: 537 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 10/141 (7%)
Query: 151 EPGEPLAPSPQEPQAVGRQSLLAKSPLRQ---ETQEAPGPREEAKGQVEARRE----SLD 203
E E +EP+A + KSP++ E +E G +EE +GQ E E D
Sbjct: 111 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 170
Query: 204 PVQEPGGQAEADGD-VPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQ 262
+E G + E + G + E E +AEA+G+ + E + E + + + E
Sbjct: 171 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK--KVEEKSEEVATKEELVAD 228
Query: 263 AEARENGEEAKELPGETLESK 283
A+ + + +P +E K
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEK 249
Score = 39.7 bits (91), Expect = 0.003
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 177 LRQETQEAPGPREEAKGQVEARRESLDPVQEP-GGQAEADGDVPGPRGEAEGQAEAKGDA 235
+++E +EA +EE + EA E + + P A + G + E EGQ E + +
Sbjct: 108 MKEEKKEAAEEKEE---EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 164
Query: 236 PGPRGEAG--GQAEAEGDAPGPRGEAG-GQAEARENGEEAKELPGETLESKNTQ 286
G + + G +E EG + GE G+ EA GEEA+ + +E K+ +
Sbjct: 165 EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218
Score = 31.6 bits (70), Expect = 0.90
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 31/159 (19%)
Query: 162 EPQAVGRQSLLAKSPLRQETQEAPGPREE--AKGQVEARRESLDPVQEPGGQAEADGDVP 219
E +A G ++ + +E E +EE A +VE ++ PV P E G P
Sbjct: 196 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV--PKSPVEEKGKSP 253
Query: 220 GPRGEAE---------GQAEAKGDAPGPRG--EAGGQA-------EAEGDAPGP------ 255
P+ E E KG +P P+ E G++ E + +P P
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Query: 256 ---RGEAGGQAEARENGEEAKELPGETLESKNTQNDFEV 291
+ E G + E +E KE P E K + +V
Sbjct: 314 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 352
Score = 30.4 bits (67), Expect = 2.0
Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 195 VEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPG 254
V + E + +E + EA+ + + ++ K AP + E G + E EG
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAK-----KSPVKATAPEVKEEEGEKEEEEGQEEE 160
Query: 255 PRGEAGGQAEARENGEEAKELPGETLESKNTQNDFE 290
+ G +++ E G KE E E + + + E
Sbjct: 161 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,443,933
Number of Sequences: 37866
Number of extensions: 874047
Number of successful extensions: 8068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 716
Number of HSP's that attempted gapping in prelim test: 5088
Number of HSP's gapped (non-prelim): 2606
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.