Search of human proteins with 27881482

Search of human proteins with 27881482

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
[Homo sapiens]
         (925 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [...  1872   0.0  
gi|27886568 interferon induced with helicase C domain 1 [Homo sa...   379   e-105
gi|149408122 RNA helicase LGP2 [Homo sapiens]                         309   7e-84
gi|29294649 dicer1 [Homo sapiens]                                     113   7e-25
gi|29294651 dicer1 [Homo sapiens]                                     113   7e-25
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]     99   2e-20
gi|76880486 activating signal cointegrator 1 complex subunit 3 i...    46   1e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    44   0.001
gi|139394648 DNA polymerase theta [Homo sapiens]                       43   0.001
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    43   0.002
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]          40   0.010
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]           40   0.010
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...    40   0.013
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...    39   0.017
gi|40217847 activating signal cointegrator 1 complex subunit 3-l...    39   0.017
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    39   0.022
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     38   0.038
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]     38   0.050
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...    37   0.065
gi|130484567 HFM1 protein [Homo sapiens]                               37   0.085
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    37   0.11 
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    37   0.11 
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    37   0.11 
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    37   0.11 
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    37   0.11 
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    37   0.11 
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    37   0.11 
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...    36   0.14 
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...    36   0.19 
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...    36   0.19 

>gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
           [Homo sapiens]
          Length = 925

 Score = 1872 bits (4849), Expect = 0.0
 Identities = 925/925 (100%), Positives = 925/925 (100%)

Query: 1   MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKF 60
           MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKF
Sbjct: 1   MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKF 60

Query: 61  LLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIP 120
           LLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIP
Sbjct: 61  LLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIP 120

Query: 121 TDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN 180
           TDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN
Sbjct: 121 TDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN 180

Query: 181 KFSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQNLSENSCPPSEVSDTNLYSP 240
           KFSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQNLSENSCPPSEVSDTNLYSP
Sbjct: 181 KFSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQNLSENSCPPSEVSDTNLYSP 240

Query: 241 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI 300
           FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI
Sbjct: 241 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI 300

Query: 301 PVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI 360
           PVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI
Sbjct: 301 PVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI 360

Query: 361 PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT 420
           PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT
Sbjct: 361 PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT 420

Query: 421 DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR 480
           DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR
Sbjct: 421 DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR 480

Query: 481 DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL 540
           DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL
Sbjct: 481 DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL 540

Query: 541 YTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESV 600
           YTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESV
Sbjct: 541 YTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESV 600

Query: 601 SRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGI 660
           SRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGI
Sbjct: 601 SRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGI 660

Query: 661 LTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGN 720
           LTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGN
Sbjct: 661 LTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGN 720

Query: 721 VIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKI 780
           VIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKI
Sbjct: 721 VIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKI 780

Query: 781 LHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKE 840
           LHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKE
Sbjct: 781 LHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKE 840

Query: 841 CFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG 900
           CFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG
Sbjct: 841 CFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG 900

Query: 901 VQTLYSKWKDFHFEKIPFDPAEMSK 925
           VQTLYSKWKDFHFEKIPFDPAEMSK
Sbjct: 901 VQTLYSKWKDFHFEKIPFDPAEMSK 925


>gi|27886568 interferon induced with helicase C domain 1 [Homo
            sapiens]
          Length = 1025

 Score =  379 bits (972), Expect = e-105
 Identities = 313/1022 (30%), Positives = 484/1022 (47%), Gaps = 149/1022 (14%)

Query: 6    RRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLE-L 64
            R  +  F+  ++  +    +L Y+  +   E  + IQ      G M+A  L L  L + +
Sbjct: 12   RYLISCFRARVKMYIQVEPVLDYLT-FLPAEVKEQIQRTVATSGNMQAVELLLSTLEKGV 70

Query: 65   QEEGWFRGFLDALDHAG--YSGLYEAIESWDFKKIE---KLEEYRLLLKRLQPEFKTRII 119
               GW R F++AL   G   +  Y   E  D          +EY  LL  LQP    +++
Sbjct: 71   WHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNLLQPTLVDKLL 130

Query: 120  PTDIISD-LSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKE 178
              D++   + E L+  E    +      G  +G  +L++ +++  KENW       L + 
Sbjct: 131  VRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQ--KENWFSAFLNVLRQT 188

Query: 179  RNK----------FSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQ--NLSENS 226
             N            SE     + +  V+   +E+++ ++ +Q   +++      N SE+S
Sbjct: 189  GNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGMENNSSESS 248

Query: 227  CPPSEV---SDTNLY-------------------------------------SP---FKP 243
               S V   SDT+L                                      SP    + 
Sbjct: 249  FADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARASPEPELQL 308

Query: 244  RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHL-KKFPQGQKGKVVFFANQIPV 302
            R YQ+E+A PA++GKN IIC PTG GKT V++ I + HL KK    + GKV+   N++ +
Sbjct: 309  RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 368

Query: 303  YEQQKSVFSKYFE---RHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVN---NLK 356
             EQ   +F K F+   +  YRV G+SG T   +   ++V++ DIII T QIL N   NL+
Sbjct: 369  VEQ---LFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLE 425

Query: 357  KGTIPS--LSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSG--------PLPQVI 406
             G      LS F+L+I DECH+T+K+  YN IM +YL QKL  +          PLPQ++
Sbjct: 426  NGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQIL 485

Query: 407  GLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESR 466
            GLTAS GVG A    +A ++I KLCA+LDA  I TVK NL++L+  + +P K F   ++ 
Sbjct: 486  GLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADAT 545

Query: 467  ISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMP 526
              D FK  + ++M   ++  +     +  +S     +FGTQ YEQW + ++K        
Sbjct: 546  REDPFKEKLLEIMTRIQTYCQ-----MSPMS-----DFGTQPYEQWAIQMEKKA----AK 591

Query: 527  DKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQD- 585
            + + + R+C        HLRKYN+AL I++  RM DA  +L+ F++  +   F  IE D 
Sbjct: 592  EGNRKERVC------AEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDS 645

Query: 586  ------------------------------LTQRFEEKLQELESVSRDPSNENPKLEDLC 615
                                          L   F E  + L+ ++ +P  EN KL  L 
Sbjct: 646  DEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLR 705

Query: 616  FILQEEYHLNPETIT-ILFVKTRALVDALKNWIEGNPKLS--FLKPGILTGRGKTNQNTG 672
              + E+Y    E+   I+F KTR    AL  WI  N K +   +K   L G G +++   
Sbjct: 706  NTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKP 765

Query: 673  MTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR 732
            MT   QK ++  F+ +G  N+LIAT+VA+EG+DI +CN+VI Y  V N I M+Q RGR R
Sbjct: 766  MTQNEQKEVISKFR-TGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRAR 824

Query: 733  ARGSKCFLLT-SNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIR 791
            A  S   L+  S +GVIE E +N ++EKMM  +I  +Q      +  KIL +Q      +
Sbjct: 825  ADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEK 884

Query: 792  DSQEKPKPVPDKENK----KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPH 847
              + K       +N       LC+ C  LAC   D+ VIE+ H+  +   FKE ++ R +
Sbjct: 885  KMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVREN 944

Query: 848  PK-PKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYS 906
                K+ + ++   +I C    C   WG  + +K  ++P +KI +FVV       +  Y 
Sbjct: 945  KALQKKCADYQINGEIIC---KCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYK 1001

Query: 907  KW 908
            KW
Sbjct: 1002 KW 1003


>gi|149408122 RNA helicase LGP2 [Homo sapiens]
          Length = 678

 Score =  309 bits (792), Expect = 7e-84
 Identities = 220/693 (31%), Positives = 360/693 (51%), Gaps = 50/693 (7%)

Query: 244 RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVY 303
           R+YQ E+ +PA++GKN II  PTG GKT  +  + + HL+        KVV   N++ + 
Sbjct: 4   RSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETV---DGAKVVVLVNRVHLV 60

Query: 304 EQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQIL---VNNLKKGTI 360
            Q    F +  +   + VT +SG          +   +D++I T ++L   + + ++   
Sbjct: 61  TQHGEEFRRMLDGR-WTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEH 119

Query: 361 PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT 420
             L++F+L++ DECH+T K   YN+IM  YL+ KL  +  PLPQV+GLTAS G G A   
Sbjct: 120 VELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQ-PLPQVLGLTASPGTGGASKL 178

Query: 421 DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR 480
           D A++++ +LCA+LD   I + ++   +L++   +P K +     R  D F  ++ +LM 
Sbjct: 179 DGAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMD 238

Query: 481 DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL 540
                      ++  LS    R+FGTQ YEQ +V + +A  +  +    +E R+      
Sbjct: 239 QIHDHL-----EMPELS----RKFGTQMYEQQVVKLSEAAALAGL----QEQRV------ 279

Query: 541 YTSHLRKYNDALIISEHARMKDALDYLKDFF--SNVRAAGFDEIEQDLTQRFEEKLQELE 598
           Y  HLR+YNDAL+I +  R  DAL  L+DF+   +V        E+ L   F+++  EL 
Sbjct: 280 YALHLRRYNDALLIHDTVRAVDALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELA 339

Query: 599 SVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSF--L 656
            ++     ENPKLE L  ILQ ++  +     I+F +TR    +L  W++    L    +
Sbjct: 340 HLATH-GPENPKLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDI 398

Query: 657 KPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYE 716
           +  +L G G ++Q+T MT   Q+ ++  F+  G  N+L+ATSVA+EG+DI  CN+V+ Y 
Sbjct: 399 RAQLLIGAGNSSQSTHMTQRDQQEVIQKFQ-DGTLNLLVATSVAEEGLDIPHCNVVVRYG 457

Query: 717 YVGNVIKMIQTRGRGRARGS-KCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAV 775
            + N I M+Q RGR RA  S   F+ T  +  +++E IN   E +M  ++  +Q  D+A 
Sbjct: 458 LLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMDQAE 517

Query: 776 FREKILHIQ-------THEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEE 828
           ++ KI  +Q         +   R++Q +  PV   E+ +LLC  C     + +D+R +E 
Sbjct: 518 YQAKIRDLQQAALTKRAAQAAQRENQRQQFPV---EHVQLLCINCMVAVGHGSDLRKVEG 574

Query: 829 CHYTVLGDAFKECF-VSR-PHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPV 886
            H+  +   F   + VSR P    K F  ++    I C  +NC   WG+ + YK+ ++PV
Sbjct: 575 THHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISC--RNCGEVWGLQMIYKSVKLPV 632

Query: 887 IKIESFVVEDIATGVQTLYSKWKDFHFEKIPFD 919
           +K+ S ++E     +Q    KW    F    FD
Sbjct: 633 LKVRSMLLETPQGRIQA--KKWSRVPFSVPDFD 663


>gi|29294649 dicer1 [Homo sapiens]
          Length = 1922

 Score =  113 bits (283), Expect = 7e-25
 Identities = 142/583 (24%), Positives = 248/583 (42%), Gaps = 79/583 (13%)

Query: 231 EVSDTNLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEH--HLKKFPQG 288
           E    N+Y+P   R YQ+EL L A    NTI+C  TG GKTF+++L+ +   +  +    
Sbjct: 35  EAIHDNIYTP---RKYQVEL-LEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFS 90

Query: 289 QKGK-VVFFANQIPVYEQQKSVFSKYFERHGYRVTGIS-GATAENVPVEQIVENNDIIIL 346
           + GK  VF  N      QQ S    + +      + +   A+       Q    + ++I+
Sbjct: 91  RNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIM 150

Query: 347 TPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVI 406
           T  + +N LK G + SLS   L++FDECH     HPY  IM      KL  +    P+++
Sbjct: 151 TCYVALNVLKNGYL-SLSDINLLVFDECHLAILDHPYREIM------KLCENCPSCPRIL 203

Query: 407 GLTASV--GVGDAKNTDE---ALDYICKLCASLDASVIATVKHNLEELEQVV-----YKP 456
           GLTAS+  G  D +  +E    L+ I K  A     ++   ++  +  E VV        
Sbjct: 204 GLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDR 263

Query: 457 QKFFRKVESRISDKFKYI------IAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYE 510
              + ++   + +   +I      +    RD+  ++K+I  D   +  +           
Sbjct: 264 SGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLG--------- 314

Query: 511 QWIVTVQKACMVFQMPD--KDEESRICKALFLYT-SHLRKYNDALIISEH---------- 557
            W        MV ++    K E+  + +   L+T + LRK +   +  EH          
Sbjct: 315 PWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIH--ALCEEHFSPASLDLKF 372

Query: 558 --ARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESVSRDPSNENPKLEDLC 615
              ++   L+ L+ +    R   F+ +E    +  +  +   +S   D   E  + E   
Sbjct: 373 VTPKVIKLLEILRKYKPYERQQ-FESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEK-- 429

Query: 616 FILQEEYHLNPET---ITILFVKTRALVDALKNWI----EGNPKLSFLKPGILTGRG--- 665
               E    +P T     I+FV+ R     L   I    + +P+L+++    +TG G   
Sbjct: 430 ---PETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGK 486

Query: 666 --KTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIK 723
               N+        Q+ +L  F+A  + N+LIATS+ +EG+DI +CNLV+ ++       
Sbjct: 487 NQPRNKQMEAEFRKQEEVLRKFRAH-ETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRS 545

Query: 724 MIQTRGRGRARGSKCFLLTSNAGVIE-KEQINMYK--EKMMND 763
            +Q++GR RA  S   +L     +   +E +  YK  EK++ +
Sbjct: 546 YVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRN 588


>gi|29294651 dicer1 [Homo sapiens]
          Length = 1922

 Score =  113 bits (283), Expect = 7e-25
 Identities = 142/583 (24%), Positives = 248/583 (42%), Gaps = 79/583 (13%)

Query: 231 EVSDTNLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEH--HLKKFPQG 288
           E    N+Y+P   R YQ+EL L A    NTI+C  TG GKTF+++L+ +   +  +    
Sbjct: 35  EAIHDNIYTP---RKYQVEL-LEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFS 90

Query: 289 QKGK-VVFFANQIPVYEQQKSVFSKYFERHGYRVTGIS-GATAENVPVEQIVENNDIIIL 346
           + GK  VF  N      QQ S    + +      + +   A+       Q    + ++I+
Sbjct: 91  RNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIM 150

Query: 347 TPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVI 406
           T  + +N LK G + SLS   L++FDECH     HPY  IM      KL  +    P+++
Sbjct: 151 TCYVALNVLKNGYL-SLSDINLLVFDECHLAILDHPYREIM------KLCENCPSCPRIL 203

Query: 407 GLTASV--GVGDAKNTDE---ALDYICKLCASLDASVIATVKHNLEELEQVV-----YKP 456
           GLTAS+  G  D +  +E    L+ I K  A     ++   ++  +  E VV        
Sbjct: 204 GLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDR 263

Query: 457 QKFFRKVESRISDKFKYI------IAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYE 510
              + ++   + +   +I      +    RD+  ++K+I  D   +  +           
Sbjct: 264 SGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLG--------- 314

Query: 511 QWIVTVQKACMVFQMPD--KDEESRICKALFLYT-SHLRKYNDALIISEH---------- 557
            W        MV ++    K E+  + +   L+T + LRK +   +  EH          
Sbjct: 315 PWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIH--ALCEEHFSPASLDLKF 372

Query: 558 --ARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESVSRDPSNENPKLEDLC 615
              ++   L+ L+ +    R   F+ +E    +  +  +   +S   D   E  + E   
Sbjct: 373 VTPKVIKLLEILRKYKPYERQQ-FESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEK-- 429

Query: 616 FILQEEYHLNPET---ITILFVKTRALVDALKNWI----EGNPKLSFLKPGILTGRG--- 665
               E    +P T     I+FV+ R     L   I    + +P+L+++    +TG G   
Sbjct: 430 ---PETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGK 486

Query: 666 --KTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIK 723
               N+        Q+ +L  F+A  + N+LIATS+ +EG+DI +CNLV+ ++       
Sbjct: 487 NQPRNKQMEAEFRKQEEVLRKFRAH-ETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRS 545

Query: 724 MIQTRGRGRARGSKCFLLTSNAGVIE-KEQINMYK--EKMMND 763
            +Q++GR RA  S   +L     +   +E +  YK  EK++ +
Sbjct: 546 YVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRN 588


>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
          Length = 2048

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 135/609 (22%), Positives = 262/609 (43%), Gaps = 107/609 (17%)

Query: 244 RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVY 303
           R+YQL ++  A+   NT++C PTG GKTF++ ++  +  + FP    GKVVF A   P+ 
Sbjct: 92  RDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFYRWFP---SGKVVFMAPTKPLV 147

Query: 304 EQQKSVFSKYF---ERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI 360
            QQ     +     + H   +TG + A+      ++I  +  ++ LTPQ++VN+L +G  
Sbjct: 148 TQQIEACYQVMGIPQSHMAEMTGSTQASTR----KEIWCSKRVLFLTPQVMVNDLSRGAC 203

Query: 361 PSLSIFTLMIFDECHNTSKQHPYNMI---MFNYLDQKLGGSSGPLPQVIGLTASVGVGDA 417
           P+  I  L+I DE H     + Y  +   +  Y +           +++ L+A+ G  D 
Sbjct: 204 PAAEIKCLVI-DEAHKALGNYAYCQVVRELVKYTNHF---------RILALSATPG-SDI 252

Query: 418 KNTDEALDYICKLCASLDASVIATVKHNLEELEQVV-YKPQKFFRKVESRISDKFKYIIA 476
           K   + +  +          +I  ++   E+   ++ Y  ++   K+   + ++   I  
Sbjct: 253 KAVQQVITNL----------LIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAIQK 302

Query: 477 QLMRDTESLAKRIC-------KDLENLSQIQ---NREFGTQKYEQWIVTVQKA------- 519
             ++  ES A+ +        +D+ NL++ Q    R+   +     IV +Q+        
Sbjct: 303 TYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGEFA 362

Query: 520 -CMVFQMPDKDEESRICKALFLYTSHLRKYNDALIIS--EHARMKDAL---DYLKDFFSN 573
            C+      +  +    ++L+ +   +      +  S  E  R +D +   ++L+  F+ 
Sbjct: 363 ICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMFAR 422

Query: 574 VR---AAGFDEIEQ-DLTQRF---EEKLQELESV------SRDPSNENPKLEDLCFILQE 620
            R   A G   I+Q D  ++F     KL++LE V      S +  N   K  D       
Sbjct: 423 TRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRD------- 475

Query: 621 EYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKC 680
                 ET  ++F   R  V  +   +  +  +  ++     G        G T   Q  
Sbjct: 476 ------ETRVMIFSSFRDSVQEIAEMLSQHQPI--IRVMTFVGHASGKSTKGFTQKEQLE 527

Query: 681 ILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR-GRARGSKCF 739
           ++  F+  G +N L++T V +EG+DI + +L+I ++   + I+++Q  GR GR R  +  
Sbjct: 528 VVKQFR-DGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIV 586

Query: 740 LLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIRDSQEKPKP 799
           ++ S             +E++ N S    Q+   ++++     I ++ + +   Q  P+ 
Sbjct: 587 IILSEG----------REERIYNQS----QSNKRSIYKA----ISSNRQVLHFYQRSPRM 628

Query: 800 VPDKENKKL 808
           VPD  N KL
Sbjct: 629 VPDGINPKL 637


>gi|76880486 activating signal cointegrator 1 complex subunit 3
           isoform a [Homo sapiens]
          Length = 2202

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 10/125 (8%)

Query: 258 KNTIICAPTGCGKTFVSLLICEHHLKK-FPQG----QKGKVVFFANQIPVYEQQKSVFSK 312
           +N +ICAPTG GKT +++L   H +++ F QG     + K+V+ A    +  +    FS+
Sbjct: 493 ENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSR 552

Query: 313 YFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQ--ILVNNLKKGTIPSLSIFTLMI 370
             E  G  V  ++G    +   +  +    +++ TP+   +V     G +    I  L+I
Sbjct: 553 RLEPLGIIVKELTGDMQLS---KSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLI 609

Query: 371 FDECH 375
            DE H
Sbjct: 610 LDEVH 614



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 7/92 (7%)

Query: 259  NTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFAN-QIPVYEQQKSVFSKYFERH 317
            N ++ APTG GKT  + L       K+P     K V+ A  +  V E+      +  E+ 
Sbjct: 1344 NVLLGAPTGSGKTVAAELAIFRVFNKYP---TSKAVYIAPLKALVRERMDDWKVRIEEKL 1400

Query: 318  GYRVTGISGATAENVPVEQIVENNDIIILTPQ 349
            G +V  ++G   +  P  + +   D+I+ TP+
Sbjct: 1401 GKKVIELTG---DVTPDMKSIAKADLIVTTPE 1429


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 5/137 (3%)

Query: 242 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIP 301
           KP   Q +     M G++ I  A TG GKT   LL    H+      ++G+        P
Sbjct: 394 KPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTP 453

Query: 302 VYE---QQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNL--K 356
             E   Q      K+ +  G RV  + G T  +  + ++    +II+ TP  +++ L   
Sbjct: 454 TRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAAN 513

Query: 357 KGTIPSLSIFTLMIFDE 373
            G + +L   T ++ DE
Sbjct: 514 SGRVTNLRRVTYVVLDE 530



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 681 ILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFL 740
           I++ FK +G   +L+ATSVA  G+D+    LV+ Y    +    +   GR    G+K + 
Sbjct: 661 IINDFK-NGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYA 719

Query: 741 LT 742
            T
Sbjct: 720 YT 721


>gi|139394648 DNA polymerase theta [Homo sapiens]
          Length = 2590

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 13/130 (10%)

Query: 255 MKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYF 314
           ++GKN +  APT  GKT V+ L+    LK+  + +K K +F    + V +++K      F
Sbjct: 106 LEGKNLVYSAPTSAGKTLVAELLI---LKRVLEMRK-KALFILPFVSVAKEKKYYLQSLF 161

Query: 315 ERHGYRVTGISGATAENVPVEQIVENNDIIILTPQI---LVNNLKKGTIPSLSIFTLMIF 371
           +  G +V G  G+T+ +     +    DI + T +    L+N L +     + +  +++ 
Sbjct: 162 QEVGIKVDGYMGSTSPSRHFSSL----DIAVCTIERANGLINRLIEEN--KMDLLGMVVV 215

Query: 372 DECHNTSKQH 381
           DE H     H
Sbjct: 216 DELHMLGDSH 225


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 55/211 (26%), Positives = 90/211 (42%), Gaps = 28/211 (13%)

Query: 524 QMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIE 583
           Q PD DE     K L  + S   KY   ++ +  A M  A++ L   +    A  +    
Sbjct: 575 QKPDTDEAEDPEKMLANFESGKHKYRQTVMFT--ATMPPAVERLARSYLRRPAVVYIGSA 632

Query: 584 QDLTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDAL 643
               +R E+K+  +        +E+ K + L  IL++ +    +   I+FV  +   D L
Sbjct: 633 GKPHERVEQKVFLM--------SESEKRKKLLAILEQGF----DPPIIIFVNQKKGCDVL 680

Query: 644 KNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEG 703
              +E   K+ +    +  G+G+  +            L   KA G  +IL+AT VA  G
Sbjct: 681 AKSLE---KMGYNACTLHGGKGQEQREFA---------LSNLKA-GAKDILVATDVAGRG 727

Query: 704 IDIAQCNLVILYEYVGNVIKMIQTRGR-GRA 733
           IDI   ++V+ Y+   N+   I   GR GRA
Sbjct: 728 IDIQDVSMVVNYDMAKNIEDYIHRIGRTGRA 758


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 17/115 (14%)

Query: 618 LQEEYHLNPETITILFVKTRALVDALKNWI--EGNPKLSFLKPGILTGRGKTNQNTGMTL 675
           L EE     E  TI+FV+T+   D L   +  +G P +           G  +Q      
Sbjct: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCI--------HGDKSQ------ 454

Query: 676 PAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR 730
           P +  +L+ F+ SG   ILIAT VA  G+D+     VI Y+Y  +    +   GR
Sbjct: 455 PERDWVLNEFR-SGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 508


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 17/115 (14%)

Query: 618 LQEEYHLNPETITILFVKTRALVDALKNWI--EGNPKLSFLKPGILTGRGKTNQNTGMTL 675
           L EE     E  TI+FV+T+   D L   +  +G P +           G  +Q      
Sbjct: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCI--------HGDKSQ------ 454

Query: 676 PAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR 730
           P +  +L+ F+ SG   ILIAT VA  G+D+     VI Y+Y  +    +   GR
Sbjct: 455 PERDWVLNEFR-SGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 508


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 17/152 (11%)

Query: 586 LTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKN 645
           L ++ E  L+ ++    +   E  KL+ LC +    Y     T  ++F+ TR  VD    
Sbjct: 236 LVKKEELTLEGIKQFYINVEREEWKLDTLCDL----YETLTITQAVIFLNTRRKVD---- 287

Query: 646 WIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGID 705
           W+             L G         M    +  I+  F+ SG   +LI T +   GID
Sbjct: 288 WLTEKMHARDFTVSALHG--------DMDQKERDVIMREFR-SGSSRVLITTDLLARGID 338

Query: 706 IAQCNLVILYEYVGNVIKMIQTRGRGRARGSK 737
           + Q +LVI Y+   N    I   GRG   G K
Sbjct: 339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 370


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 17/152 (11%)

Query: 586 LTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKN 645
           L ++ E  L+ +     +   E  KL+ LC +    Y     T  ++F+ TR  VD    
Sbjct: 235 LVKKEELTLEGIRQFYINVEREEWKLDTLCDL----YETLTITQAVIFINTRRKVD---- 286

Query: 646 WIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGID 705
           W+             + G         M    +  I+  F+ SG   +LI T +   GID
Sbjct: 287 WLTEKMHARDFTVSAMHG--------DMDQKERDVIMREFR-SGSSRVLITTDLLARGID 337

Query: 706 IAQCNLVILYEYVGNVIKMIQTRGRGRARGSK 737
           + Q +LVI Y+   N    I   GRG   G K
Sbjct: 338 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRK 369


>gi|40217847 activating signal cointegrator 1 complex subunit 3-like
           1 [Homo sapiens]
          Length = 2136

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)

Query: 258 KNTIICAPTGCGKTFVSLLICEHHLKKF------PQGQKGKVVFFANQIPVYEQQKSVFS 311
           +N ++CAPTG GKT V+L+     + K             K+++ A    + ++    F 
Sbjct: 497 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 556

Query: 312 KYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQIL-VNNLKKGTIPSLSIFTLMI 370
           K    +G  V  ++G   ++   ++ +    II+ TP+   +   K G      +  L+I
Sbjct: 557 KRLATYGITVAELTG---DHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLII 613

Query: 371 FDECH 375
            DE H
Sbjct: 614 LDEIH 618



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 39/154 (25%), Positives = 67/154 (43%), Gaps = 34/154 (22%)

Query: 259  NTIICAPTGCGKTFVSLLICEHH--LKKFPQGQKGKVVFFANQIPVYEQ-QKSVFSKYFE 315
            N  + APTG GKT     IC     L+   Q  +G+ V+      + EQ     + K+ +
Sbjct: 1345 NVFVGAPTGSGKT-----ICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQD 1399

Query: 316  RHGYRVTGISGATAENVPVEQIVENNDIIILTPQ---ILVNNLKKGTIPSLSIFTLMIFD 372
            R   +V  ++G T+ ++   +++   +III TP+   IL    K+    ++    L + D
Sbjct: 1400 RLNKKVVLLTGETSTDL---KLLGKGNIIISTPEKWDILSRRWKQR--KNVQNINLFVVD 1454

Query: 373  ECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVI 406
            E H                   +GG +GP+ +VI
Sbjct: 1455 EVH------------------LIGGENGPVLEVI 1470


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
           partial [Homo sapiens]
          Length = 1700

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 10/125 (8%)

Query: 258 KNTIICAPTGCGKTFVSLLICEHHLKKF------PQGQKGKVVFFANQIPVYEQQKSVFS 311
           +N ++CAPTG GKT V+L+     + K             K+++ A    + ++    F 
Sbjct: 61  ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 120

Query: 312 KYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQIL-VNNLKKGTIPSLSIFTLMI 370
           K    +G  V  ++G   ++   ++ +    II+ TP+   +   K G      +  L++
Sbjct: 121 KRLATYGITVAELTG---DHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIV 177

Query: 371 FDECH 375
            DE H
Sbjct: 178 LDEIH 182



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 40/157 (25%)

Query: 259  NTIICAPTGCGKTFVSLLICEHH--LKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFE- 315
            N  + APTG GKT     IC     L+   Q  +G+ V+     P+   Q+ V+  ++E 
Sbjct: 909  NVFVGAPTGSGKT-----ICAEFAILRMLLQNSEGRCVYIT---PMRLWQEQVYMDWYEK 960

Query: 316  ---RHGYRVTGISGATAENVPVEQIVENNDIIILTPQ---ILVNNLKKGTIPSLSIFTLM 369
               R   +V  ++G T+ ++   +++   +III TP+   IL    K+    ++    L 
Sbjct: 961  FQDRLNKKVVLLTGETSTDL---KLLGKGNIIISTPEKWDILSRRWKQR--KNVQNINLF 1015

Query: 370  IFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVI 406
            + DE H                   +GG +GP+ +VI
Sbjct: 1016 VVDEVH------------------LIGGENGPVLEVI 1034


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 83/391 (21%), Positives = 157/391 (40%), Gaps = 72/391 (18%)

Query: 417 AKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIA 476
           A+ T+EA     KL A +D  +    K + EE   +  +  +  ++V   +    +  IA
Sbjct: 423 AQKTEEARR---KLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479

Query: 477 QLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICK 536
           +L +  E    R  ++L    Q + REF     EQ  V ++K+   +    +++E +   
Sbjct: 480 KLQKLHEKELARKEQELTKKLQTREREF----QEQMKVALEKSQSEYLKISQEKEQQESL 535

Query: 537 ALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQE 596
           AL           + L + + A + ++ + L+D              Q   + +  ++ E
Sbjct: 536 AL-----------EELELQKKAILTESENKLRDL-------------QQEAETYRTRILE 571

Query: 597 LESVSRDPSNENP-KLEDLCFILQEEYHLNPETITILFVKTRALVDALKN-----WIEGN 650
           LES       EN  + +DL   L+ E + + + IT++  K +  +++LK+     W E  
Sbjct: 572 LESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE-- 629

Query: 651 PKLSFLKPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVAD------EGI 704
            KL  L         K    T M    +KC  +      D  I+    + +      E +
Sbjct: 630 -KLQVL---------KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKL 679

Query: 705 DIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKM---M 761
           D+ Q  L  L   +  V+K         AR      L     V+ K+Q +  K+++   M
Sbjct: 680 DVKQTELESLSSELSEVLK---------ARHK----LEEELSVL-KDQTDKMKQELEAKM 725

Query: 762 NDSILRLQTWDEAVFREKILHIQTHEKFIRD 792
           ++     Q   +++ +E  + IQ  EK ++D
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKD 756


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 37.7 bits (86), Expect = 0.050
 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 18/122 (14%)

Query: 618 LQEEYHLNPETITILFVKTRALVDALKNWI--EGNPKLSFLKPGILTGRGKTNQNTGMTL 675
           L EE     E  TI+FV+T+   D L   +  +G P +           G  +Q      
Sbjct: 332 LMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGI--------HGDKSQQE---- 379

Query: 676 PAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARG 735
             +  +L+ FK  G   ILIAT VA  G+D+     VI Y+Y  +    I   GR  AR 
Sbjct: 380 --RDWVLNEFK-HGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGR-TARS 435

Query: 736 SK 737
           +K
Sbjct: 436 TK 437


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score = 37.4 bits (85), Expect = 0.065
 Identities = 64/298 (21%), Positives = 115/298 (38%), Gaps = 59/298 (19%)

Query: 131 LINQECEEILQICSTKGMMAGAEKLVECLLRSDKE------------------------- 165
           +IN E E  ++I   + M A A+  +E L+R  +                          
Sbjct: 84  IINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYNSESSVDNAASQTPIGRNLGRNDI 143

Query: 166 --------NWPKTLKLALEKERNKFSELWIVEKG--IKDVETEDLED------KMETSDI 209
                   NW +     +E E+ K+++L  V+K   I+   T  + +      + E  +I
Sbjct: 144 VGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNI 203

Query: 210 QIFYQEDPECQNLSENSCP--------PSEVSDTNLYSPFKPRNYQLELALPAMKGKNTI 261
                +  E + + + +C         P  +         KP   Q +     ++G + I
Sbjct: 204 TCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLI 263

Query: 262 ICAPTGCGKTFVSLLICEHHLKKFPQGQKGK------VVFFANQIPVYEQQKSVFSKYFE 315
           + A TG GKT   L+    HL   P  ++ +      V+    ++ ++ + +   SKY  
Sbjct: 264 VVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAEC--SKYSY 321

Query: 316 RHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDE 373
           + G +   I G    N  +E I +  DIII TP  L N+L+     +L   T ++ DE
Sbjct: 322 K-GLKSICIYGGRNRNGQIEDISKGVDIIIATPGRL-NDLQMNNSVNLRSITYLVIDE 377


>gi|130484567 HFM1 protein [Homo sapiens]
          Length = 1435

 Score = 37.0 bits (84), Expect = 0.085
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 4/120 (3%)

Query: 258 KNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKG-KVVFFANQIPVYEQQKSVFSKYFER 316
           +N +ICAPTG GKT V  L     L + P      K+V+ A    +  Q+   + + F  
Sbjct: 297 RNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDWKEKFGP 356

Query: 317 HGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPSL-SIFTLMIFDECH 375
            G     ++G T  +   E  +++  II+ TP+   +  +K    SL  +  L + DE H
Sbjct: 357 IGLNCKELTGDTVMDDLFE--IQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLIDEVH 414


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 41/162 (25%), Positives = 68/162 (41%), Gaps = 6/162 (3%)

Query: 216 DPECQNLSENSCPPSEVSDTNLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSL 275
           +P C       C P  + +       KP   Q +     ++G + I  A TG GKT   L
Sbjct: 238 NPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYL 297

Query: 276 LICEHHLKKFP--QGQKGK--VVFFANQIPVYEQQKSVFSKYFERHGYRVTGISGATAEN 331
           +    HL   P  +GQ+ +  ++       +  Q +    KY  + G R   + G    +
Sbjct: 298 MPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRD 356

Query: 332 VPVEQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDE 373
             +E++ +  DIII TP  L N+L+     +L   T ++ DE
Sbjct: 357 EQIEELKKGVDIIIATPGRL-NDLQMSNFVNLKNITYLVLDE 397



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 11/125 (8%)

Query: 682 LDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR-GRA--RGSKC 738
           L+ FK +G   ILIAT +A  G+D+     V  +++  N+ + +   GR GRA   G   
Sbjct: 530 LENFK-TGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSI 588

Query: 739 FLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIRDSQEKPK 798
             LT N   +  E IN+ +    N SI      +E V   +       ++ +    E+P+
Sbjct: 589 TTLTRNDWRVASELINILER--ANQSIP-----EELVSMAERFKAHQQKREMERKMERPQ 641

Query: 799 PVPDK 803
             P K
Sbjct: 642 GRPKK 646


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 20/198 (10%)

Query: 442  VKHNLEELEQVVYKPQKFF---RKVESRISDKFKYI------IAQLMRDTESLAKRICKD 492
            V+H  ++LE  V + Q       +  + ++DK   +      +  ++ + E  A ++ KD
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309

Query: 493  LENLS-QIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDA 551
            + +LS Q+Q+ +   Q+      T QK  +  ++   +EE    +         ++  + 
Sbjct: 1310 VASLSSQLQDTQELLQEE-----TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364

Query: 552  LIISEHARMKDALDYLKDFFSNVRAAG-----FDEIEQDLTQRFEEKLQELESVSRDPSN 606
             I + + ++ D+   L+DF S V A       F +  ++LTQ++EEK    + + +  + 
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 607  ENPKLEDLCFILQEEYHL 624
               +L+DL   L  +  L
Sbjct: 1425 LQQELDDLVVDLDNQRQL 1442


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 20/198 (10%)

Query: 442  VKHNLEELEQVVYKPQKFF---RKVESRISDKFKYI------IAQLMRDTESLAKRICKD 492
            V+H  ++LE  V + Q       +  + ++DK   +      +  ++ + E  A ++ KD
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316

Query: 493  LENLS-QIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDA 551
            + +LS Q+Q+ +   Q+      T QK  +  ++   +EE    +         ++  + 
Sbjct: 1317 VASLSSQLQDTQELLQEE-----TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371

Query: 552  LIISEHARMKDALDYLKDFFSNVRAAG-----FDEIEQDLTQRFEEKLQELESVSRDPSN 606
             I + + ++ D+   L+DF S V A       F +  ++LTQ++EEK    + + +  + 
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 607  ENPKLEDLCFILQEEYHL 624
               +L+DL   L  +  L
Sbjct: 1432 LQQELDDLVVDLDNQRQL 1449


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 20/198 (10%)

Query: 442  VKHNLEELEQVVYKPQKFF---RKVESRISDKFKYI------IAQLMRDTESLAKRICKD 492
            V+H  ++LE  V + Q       +  + ++DK   +      +  ++ + E  A ++ KD
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316

Query: 493  LENLS-QIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDA 551
            + +LS Q+Q+ +   Q+      T QK  +  ++   +EE    +         ++  + 
Sbjct: 1317 VASLSSQLQDTQELLQEE-----TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371

Query: 552  LIISEHARMKDALDYLKDFFSNVRAAG-----FDEIEQDLTQRFEEKLQELESVSRDPSN 606
             I + + ++ D+   L+DF S V A       F +  ++LTQ++EEK    + + +  + 
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 607  ENPKLEDLCFILQEEYHL 624
               +L+DL   L  +  L
Sbjct: 1432 LQQELDDLVVDLDNQRQL 1449


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 20/198 (10%)

Query: 442  VKHNLEELEQVVYKPQKFF---RKVESRISDKFKYI------IAQLMRDTESLAKRICKD 492
            V+H  ++LE  V + Q       +  + ++DK   +      +  ++ + E  A ++ KD
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309

Query: 493  LENLS-QIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDA 551
            + +LS Q+Q+ +   Q+      T QK  +  ++   +EE    +         ++  + 
Sbjct: 1310 VASLSSQLQDTQELLQEE-----TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364

Query: 552  LIISEHARMKDALDYLKDFFSNVRAAG-----FDEIEQDLTQRFEEKLQELESVSRDPSN 606
             I + + ++ D+   L+DF S V A       F +  ++LTQ++EEK    + + +  + 
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 607  ENPKLEDLCFILQEEYHL 624
               +L+DL   L  +  L
Sbjct: 1425 LQQELDDLVVDLDNQRQL 1442


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 50/215 (23%), Positives = 93/215 (43%), Gaps = 19/215 (8%)

Query: 416 DAKNTDEALDYICKLCASL----------DASVIATVKHNLEELEQVVYKPQKFFRKVES 465
           D K+T++ L+ I K               D  V   +KH   + +++  + QK   KVE 
Sbjct: 368 DVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEE 427

Query: 466 --RISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNR-EFGTQKYEQWIVTVQKACMV 522
              I  K   II +      +L K   K+ + L ++ +  +  TQ  ++   + +K  M 
Sbjct: 428 FKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMG 487

Query: 523 FQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEI 582
           F     +  S++  A      +L ++N A  +S+  + K+AL    +     R A   +I
Sbjct: 488 FSKSVNEARSKMDVAQSELDIYLSRHNTA--VSQLTKAKEALIAASETLKE-RKAAIRDI 544

Query: 583 EQDLTQ---RFEEKLQELESVSRDPSNENPKLEDL 614
           E  L Q     +EK +EL+ ++++ +N    + DL
Sbjct: 545 EGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDL 579



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 19/79 (24%), Positives = 43/79 (54%), Gaps = 1/79 (1%)

Query: 719 GNVIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAV-FR 777
           G +I+   T   G ++  K  + +S    I +E++N  + ++ NDS   +Q  ++ V   
Sbjct: 742 GQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLE 801

Query: 778 EKILHIQTHEKFIRDSQEK 796
           E+++ ++  E+ +R++ EK
Sbjct: 802 ERVVKLRHSEREMRNTLEK 820


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 50/215 (23%), Positives = 93/215 (43%), Gaps = 19/215 (8%)

Query: 416 DAKNTDEALDYICKLCASL----------DASVIATVKHNLEELEQVVYKPQKFFRKVES 465
           D K+T++ L+ I K               D  V   +KH   + +++  + QK   KVE 
Sbjct: 368 DVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEE 427

Query: 466 --RISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNR-EFGTQKYEQWIVTVQKACMV 522
              I  K   II +      +L K   K+ + L ++ +  +  TQ  ++   + +K  M 
Sbjct: 428 FKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMG 487

Query: 523 FQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEI 582
           F     +  S++  A      +L ++N A  +S+  + K+AL    +     R A   +I
Sbjct: 488 FSKSVNEARSKMDVAQSELDIYLSRHNTA--VSQLTKAKEALIAASETLKE-RKAAIRDI 544

Query: 583 EQDLTQ---RFEEKLQELESVSRDPSNENPKLEDL 614
           E  L Q     +EK +EL+ ++++ +N    + DL
Sbjct: 545 EGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDL 579



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 19/79 (24%), Positives = 43/79 (54%), Gaps = 1/79 (1%)

Query: 719 GNVIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAV-FR 777
           G +I+   T   G ++  K  + +S    I +E++N  + ++ NDS   +Q  ++ V   
Sbjct: 742 GQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLE 801

Query: 778 EKILHIQTHEKFIRDSQEK 796
           E+++ ++  E+ +R++ EK
Sbjct: 802 ERVVKLRHSEREMRNTLEK 820


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
           [Homo sapiens]
          Length = 1828

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 7/95 (7%)

Query: 678 QKCILDAFKASG--DHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARG 735
           +K  LD F A G  D   L++T     GI++A  + V++++   N    +Q + R    G
Sbjct: 846 RKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIG 905

Query: 736 SK----CFLLTSNAGVIEKEQINMYKEKMMNDSIL 766
            K     + L +  G +E+E I   K+KM+ D ++
Sbjct: 906 QKKQVNIYRLVTK-GTVEEEIIERAKKKMVLDHLV 939


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 41/169 (24%), Positives = 68/169 (40%), Gaps = 19/169 (11%)

Query: 213 YQEDPECQNLSENSCPPSEVSDTNLYSPFKP-RNYQLELALPAMKGKNTIICAPTGCGKT 271
           ++E   CQ L+ N            Y+   P + Y + + L    G++ + CA TG GKT
Sbjct: 290 FEEANLCQTLNNNIAKAG-------YTKLTPVQKYSIPIILA---GRDLMACAQTGSGKT 339

Query: 272 FVSLLICEHHL-------KKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGI 324
              LL    H+        +F + Q+ + +  A    +  Q      K+      R   I
Sbjct: 340 AAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVI 399

Query: 325 SGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDE 373
            G T     + QIV+  +I+  TP  L++ + K  I  L     ++ DE
Sbjct: 400 YGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKI-GLKQIKYLVLDE 447


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 41/169 (24%), Positives = 68/169 (40%), Gaps = 19/169 (11%)

Query: 213 YQEDPECQNLSENSCPPSEVSDTNLYSPFKP-RNYQLELALPAMKGKNTIICAPTGCGKT 271
           ++E   CQ L+ N            Y+   P + Y + + L    G++ + CA TG GKT
Sbjct: 290 FEEANLCQTLNNNIAKAG-------YTKLTPVQKYSIPIILA---GRDLMACAQTGSGKT 339

Query: 272 FVSLLICEHHL-------KKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGI 324
              LL    H+        +F + Q+ + +  A    +  Q      K+      R   I
Sbjct: 340 AAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVI 399

Query: 325 SGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDE 373
            G T     + QIV+  +I+  TP  L++ + K  I  L     ++ DE
Sbjct: 400 YGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKI-GLKQIKYLVLDE 447


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,004,427
Number of Sequences: 37866
Number of extensions: 1611500
Number of successful extensions: 4926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 4795
Number of HSP's gapped (non-prelim): 155
length of query: 925
length of database: 18,247,518
effective HSP length: 112
effective length of query: 813
effective length of database: 14,006,526
effective search space: 11387305638
effective search space used: 11387305638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.