BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|121114298 cullin 4B isoform 1 [Homo sapiens] (913 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|121114298 cullin 4B isoform 1 [Homo sapiens] 1786 0.0 gi|121114302 cullin 4B isoform 2 [Homo sapiens] 1742 0.0 gi|57165424 cullin 4A isoform 1 [Homo sapiens] 1243 0.0 gi|11140811 cullin 4A isoform 2 [Homo sapiens] 1138 0.0 gi|4503165 cullin 3 [Homo sapiens] 503 e-142 gi|32307161 cullin 1 [Homo sapiens] 339 6e-93 gi|19482174 cullin 2 [Homo sapiens] 308 1e-83 gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1 ... 238 1e-62 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 63 1e-09 gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens] 63 1e-09 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 57 1e-07 gi|161016767 mucin 21 [Homo sapiens] 56 1e-07 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 51 4e-06 gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 47 6e-05 gi|40807452 peroxisome proliferator-activated receptor gamma, co... 46 1e-04 gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 45 4e-04 gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 44 5e-04 gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 42 0.003 gi|28559039 mediator complex subunit 1 [Homo sapiens] 42 0.003 gi|91982772 mucin 17 [Homo sapiens] 42 0.003 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 42 0.003 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.004 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.004 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.004 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.004 gi|34452681 ring finger protein 10 [Homo sapiens] 41 0.004 gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens] 41 0.004 gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens] 41 0.004 gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 40 0.008 gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 40 0.008 >gi|121114298 cullin 4B isoform 1 [Homo sapiens] Length = 913 Score = 1786 bits (4625), Expect = 0.0 Identities = 913/913 (100%), Positives = 913/913 (100%) Query: 1 MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN 60 MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN Sbjct: 1 MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN 60 Query: 61 SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR Sbjct: 61 SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS Sbjct: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180 Query: 181 TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL 240 TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL Sbjct: 181 TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL 240 Query: 241 YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM 300 YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM Sbjct: 241 YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM 300 Query: 301 IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360 IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG Sbjct: 301 IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360 Query: 361 EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR 420 EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR Sbjct: 361 EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR 420 Query: 421 LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF 480 LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF Sbjct: 421 LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF 480 Query: 481 SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF 540 SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF Sbjct: 481 SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF 540 Query: 541 INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK 600 INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK Sbjct: 541 INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK 600 Query: 601 DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI 660 DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI Sbjct: 601 DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI 660 Query: 661 QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK 720 QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK Sbjct: 661 QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK 720 Query: 721 LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR 780 LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR Sbjct: 721 LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR 780 Query: 781 TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE 840 TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE Sbjct: 781 TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE 840 Query: 841 RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME 900 RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME Sbjct: 841 RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME 900 Query: 901 RDKENPNQYNYIA 913 RDKENPNQYNYIA Sbjct: 901 RDKENPNQYNYIA 913 >gi|121114302 cullin 4B isoform 2 [Homo sapiens] Length = 895 Score = 1742 bits (4512), Expect = 0.0 Identities = 891/891 (100%), Positives = 891/891 (100%) Query: 23 GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 82 GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS Sbjct: 5 GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 64 Query: 83 SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 142 SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS Sbjct: 65 SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 124 Query: 143 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 202 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF Sbjct: 125 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 184 Query: 203 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 262 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ Sbjct: 185 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 244 Query: 263 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 322 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP Sbjct: 245 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 304 Query: 323 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 382 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ Sbjct: 305 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 364 Query: 383 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 442 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA Sbjct: 365 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 424 Query: 443 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 502 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG Sbjct: 425 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 484 Query: 503 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 562 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL Sbjct: 485 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 544 Query: 563 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 622 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS Sbjct: 545 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 604 Query: 623 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 682 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL Sbjct: 605 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 664 Query: 683 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 742 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE Sbjct: 665 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 724 Query: 743 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 802 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI Sbjct: 725 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 784 Query: 803 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 862 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK Sbjct: 785 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 844 Query: 863 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA Sbjct: 845 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895 >gi|57165424 cullin 4A isoform 1 [Homo sapiens] Length = 759 Score = 1243 bits (3217), Expect = 0.0 Identities = 620/749 (82%), Positives = 683/749 (91%), Gaps = 5/749 (0%) Query: 168 ASVHHANGLAKSSTTVSSFANSKPGSA---KKLVIKNFKDKPKLPENYTDETWQKLKEAV 224 A V NGL K + + A +KPG A KKLVIKNF+D+P+LP+NYT +TW+KL EAV Sbjct: 13 ALVGRTNGLTKPAALAA--APAKPGGAGGSKKLVIKNFRDRPRLPDNYTQDTWRKLHEAV 70 Query: 225 EAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVL 284 A+Q+STSI+YNLEELYQAVENLCS+K+S LYKQLRQ CEDH++AQI FREDSLDSVL Sbjct: 71 RAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVL 130 Query: 285 FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQN 344 FLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYVLQNS LPSIWDMGLELFR HIISD+ VQ+ Sbjct: 131 FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQS 190 Query: 345 KTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKL 404 KTIDGILLLIERER+GEA+DRSLLRSLL MLSDLQ+Y+DSFE +FLEETN LYAAEGQ+L Sbjct: 191 KTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRL 250 Query: 405 MQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNL 464 MQEREVPEYL+HV+KRLEEE DR+ITYLD +TQK LIA VEKQLLGEHLTAILQKGL++L Sbjct: 251 MQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHL 310 Query: 465 LDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKD 524 LDENR+ DL+ +YQLFSRVRGG Q LLQ W EYIK FG+ IVINPEKDK MVQ+LLDFKD Sbjct: 311 LDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKD 370 Query: 525 KVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELE 584 KVDH+I++CF KNE+F+N MKE+FETFINKRPNKPAELIAK+VDSKLRAGNKEATDEELE Sbjct: 371 KVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELE 430 Query: 585 KMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 644 + LDKIMI+FRFI+GKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK Sbjct: 431 RTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 490 Query: 645 LEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKL 704 LEGMFKDMELSKDIM+ FKQ+MQNQ+ G I+LTVNILTMGYWPTY PMEVHL PEM+KL Sbjct: 491 LEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMIKL 550 Query: 705 QEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL 764 QE+FK FYLGKHSGRKLQWQ+TLGH VLKAEFKEGKKE QVSLFQTLVLLMFNEG+ FS Sbjct: 551 QEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSF 610 Query: 765 EEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKIN 824 EEIK ATGIED ELRRTLQSLACGKARVL K+PKGK++EDGDKFI N +FKHKLFRIKIN Sbjct: 611 EEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKIN 670 Query: 825 QIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPA 884 QIQMKETVEEQ STTERVFQDRQYQIDAAIVRIMKMRKTL HNLLVSE+YNQLKFPVKP Sbjct: 671 QIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPG 730 Query: 885 DLKKRIESLIDRDYMERDKENPNQYNYIA 913 DLKKRIESLIDRDYMERDK+NPNQY+Y+A Sbjct: 731 DLKKRIESLIDRDYMERDKDNPNQYHYVA 759 >gi|11140811 cullin 4A isoform 2 [Homo sapiens] Length = 659 Score = 1138 bits (2943), Expect = 0.0 Identities = 564/658 (85%), Positives = 613/658 (93%) Query: 256 LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV 315 LYKQLRQ CEDH++AQI FREDSLDSVLFLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYV Sbjct: 2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYV 61 Query: 316 LQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSML 375 LQNS LPSIWDMGLELFR HIISD+ VQ+KTIDGILLLIERER+GEA+DRSLLRSLL ML Sbjct: 62 LQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGML 121 Query: 376 SDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 435 SDLQ+Y+DSFE +FLEETN LYAAEGQ+LMQEREVPEYL+HV+KRLEEE DR+ITYLD + Sbjct: 122 SDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHS 181 Query: 436 TQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWI 495 TQK LIA VEKQLLGEHLTAILQKGL++LLDENR+ DL+ +YQLFSRVRGG Q LLQ W Sbjct: 182 TQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWS 241 Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555 EYIK FG+ IVINPEKDK MVQ+LLDFKDKVDH+I++CF KNE+F+N MKE+FETFINKR Sbjct: 242 EYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKR 301 Query: 556 PNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRL 615 PNKPAELIAK+VDSKLRAGNKEATDEELE+ LDKIMI+FRFI+GKDVFEAFYKKDLAKRL Sbjct: 302 PNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRL 361 Query: 616 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNI 675 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIM+ FKQ+MQNQ+ G I Sbjct: 362 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPI 421 Query: 676 ELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAE 735 +LTVNILTMGYWPTY PMEVHL PEM+KLQE+FK FYLGKHSGRKLQWQ+TLGH VLKAE Sbjct: 422 DLTVNILTMGYWPTYTPMEVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAE 481 Query: 736 FKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAK 795 FKEGKKE QVSLFQTLVLLMFNEG+ FS EEIK ATGIED ELRRTLQSLACGKARVL K Sbjct: 482 FKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIK 541 Query: 796 NPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIV 855 +PKGK++EDGDKFI N +FKHKLFRIKINQIQMKETVEEQ STTERVFQDRQYQIDAAIV Sbjct: 542 SPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIV 601 Query: 856 RIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913 RIMKMRKTL HNLLVSE+YNQLKFPVKP DLKKRIESLIDRDYMERDK+NPNQY+Y+A Sbjct: 602 RIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 659 >gi|4503165 cullin 3 [Homo sapiens] Length = 768 Score = 503 bits (1296), Expect = e-142 Identities = 291/749 (38%), Positives = 440/749 (58%), Gaps = 48/749 (6%) Query: 208 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 267 + E Y + W LK A++ IQ + + EELY+ + +K LY LR++ +H Sbjct: 25 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEH 84 Query: 268 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 325 + I++ RED L+S+ FL+ +++ W +H M+MIR I +++DR YV QN++ +++ Sbjct: 85 L---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNV-ENVY 140 Query: 326 DMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QI 380 ++GL +FR ++ +++ +L +I RER GE +DR +R+ ML L + Sbjct: 141 NLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSV 200 Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSL 440 Y++ FE FLE + + E QK + E Y+ V R+ EE +R++ LD++T++ + Sbjct: 201 YEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPI 260 Query: 441 IATVEKQLLGEHLTAILQ---KGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEY 497 + VE++L+ +H+ I++ GL ++L + +DL +Y+LFSRV G++ + + Y Sbjct: 261 VKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSY 320 Query: 498 IKAFGSTIVINPEKDKTMV---QELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINK 554 ++ G +V + K V Q LLD K + D + F + F + FE F+N Sbjct: 321 LREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNL 380 Query: 555 RPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 614 P E ++ ++D KL+ G K T++E+E +LDK M++FRF+ KDVFE +YK+ LA+R Sbjct: 381 NSRSP-EYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARR 439 Query: 615 LLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVP-G 673 LL KS S D+EK+M+SKLK ECG FTSKLEGMF+DM +S M +F+Q++Q V G Sbjct: 440 LLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLG 499 Query: 674 NIELTVNILTMGYWPTY-VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVL 732 ++LTV +LT GYWPT + ++PP EIF+ FYL KHSGR+L Q +G L Sbjct: 500 GVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADL 559 Query: 733 KAEF-----KEGKKE-----------------LQVSLFQTLVLLMFNEGEEFSLEEIKQA 770 A F KE E LQVS FQ +L++FN E+++ EEI+Q Sbjct: 560 NATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQE 619 Query: 771 TGIEDGELRRTLQSLACGK--ARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQM 828 T I + EL R LQSLACGK RVL K PK K+IE+G F ND F KL R+KI + Sbjct: 620 TDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAA 679 Query: 829 K--ETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLK--FPVKPA 884 K E+ E+ T ++V DR+++I+AAIVRIMK RK + HN+LV+EV QLK F P Sbjct: 680 KQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPV 739 Query: 885 DLKKRIESLIDRDYMERDKENPNQYNYIA 913 +KKRIE LI+R+Y+ R E+ Y Y+A Sbjct: 740 VIKKRIEGLIEREYLARTPEDRKVYTYVA 768 >gi|32307161 cullin 1 [Homo sapiens] Length = 776 Score = 339 bits (870), Expect = 6e-93 Identities = 239/768 (31%), Positives = 391/768 (50%), Gaps = 77/768 (10%) Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSYKISAN----------------- 255 D+ W L+ ++ + S+ K ELY V N C+ +N Sbjct: 18 DQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQT 77 Query: 256 ----------LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRS 305 LYK+L++ ++++ + + ED +D + LK + W+++ ++ Sbjct: 78 PGGAQFVGLELYKRLKEFLKNYL-TNLLKDGEDLMDESV-LKFYTQQWEDYRFSSKVLNG 135 Query: 306 IFLFLDRTYVLQN-----SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360 I +L+R +V + + I+ + L +R + + + + + +L LIE+ERNG Sbjct: 136 ICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF--RPLNKQVTNAVLKLIEKERNG 193 Query: 361 EAIDRSLLRSLLSMLSDL--------------QIYQDSFEQRFLEETNRLYAAEGQKLMQ 406 E I+ L+ ++ +L +Y++SFE +FL +T R Y E + +Q Sbjct: 194 ETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQ 253 Query: 407 EREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLD 466 + V EY+ RL EE R+ YL ++TQ L E+ L+ +HL I NLLD Sbjct: 254 QNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLD 312 Query: 467 ENRIQDLSLLYQLFSRVRGGVQVLLQ--------QWIEYIKAFGSTIVINPEKDKTMVQE 518 ++ +DL +Y L SR++ G+ L + Q + I+ G + +P K VQ Sbjct: 313 ADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDP---KMYVQT 369 Query: 519 LLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRP--------NKPAELIAKYVDSK 570 +LD K + ++ F + F+ A+ +A FIN +K EL+A+Y DS Sbjct: 370 VLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSL 429 Query: 571 LRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSML 630 L+ +K + ELE L+++M++F++I KDVF+ FY K LAKRL+ SAS DAE SM+ Sbjct: 430 LKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMI 489 Query: 631 SKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTY 690 SKLK CG +TSKL+ MF+D+ +SKD+ QFK+++ N P +++ ++ +L+ G WP Sbjct: 490 SKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSE-PLDLDFSIQVLSSGSWPFQ 548 Query: 691 VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQT 750 LP E+ + + F FY +HSGRKL W L L + + LQ S FQ Sbjct: 549 QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQM 608 Query: 751 LVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLA-KNPKGKDIE-DGDKF 808 +LL +N + ++++++ +T I+ L + LQ L K VL +N ++E D Sbjct: 609 AILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTL 668 Query: 809 I-CNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHN 867 I +K+K R+ IN E +EQ +T + + +DR+ I AAIVRIMKMRK L H Sbjct: 669 IKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQ 728 Query: 868 LLVSEVYNQLKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 913 L+ EV QL KP +KK I+ LI+++Y+ER + Y+Y+A Sbjct: 729 QLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776 >gi|19482174 cullin 2 [Homo sapiens] Length = 745 Score = 308 bits (790), Expect = 1e-83 Identities = 212/743 (28%), Positives = 381/743 (51%), Gaps = 51/743 (6%) Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLC---SYKISANLYKQLRQICEDHIK 269 DETW KL ++A+ + + + + + LC + LY + + E+H++ Sbjct: 11 DETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVR 70 Query: 270 AQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSM--------- 320 +H+ +S + VL + R W+ + + + ++ +L+ ++ +N + Sbjct: 71 -HLHKRVLESEEQVLVM--YHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGY 127 Query: 321 --------LPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLL 372 L I ++ L+++R ++ + +Q I +L I+ +R GE ++ ++ ++ Sbjct: 128 GGVDMNEPLMEIGELALDMWRKLMV--EPLQAILIRMLLREIKNDRGGEDPNQKVIHGVI 185 Query: 373 SMLSD---------LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEE 423 + L+ YQ+ FE FL ET Y E L+QE +Y+ V RL++ Sbjct: 186 NSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKD 245 Query: 424 EADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRV 483 E R YL ++ +I +++++ +HL L +N++ + + D++ +Y L V Sbjct: 246 EEIRCRKYLHPSSYTKVIHECQQRMVADHLQ-FLHAECHNIIRQEKKNDMANMYVLLRAV 304 Query: 484 RGGVQVLLQQWIEYIKAFG--STIVINPEKDKTM-VQELLDFKDKVDHIIDICFLKNEKF 540 G+ ++Q+ +I G +T + E T+ V+ +L+ K +I+ ++ F Sbjct: 305 STGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHF 364 Query: 541 INAMKEAFETFINKRPNKPA----ELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRF 596 ++A+ +A + +N R K EL+AKY D+ L+ K T+ E+E L + +F++ Sbjct: 365 MSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFITVFKY 424 Query: 597 IYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSK 656 I KDVF+ FY + LAKRL+ G S S+D+E++M++KLK CG FTSKL M+ DM +S Sbjct: 425 IDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSA 484 Query: 657 DIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVH-LPPEMVKLQEIFKTFY 712 D+ +F +++NQ+ + I + +L G WP T P +P E+ K ++F+ FY Sbjct: 485 DLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFY 544 Query: 713 LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATG 772 SGRKL W L +K + V+ +Q VLL FN E S +E++ +T Sbjct: 545 SQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQ 604 Query: 773 IEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETV 832 + + EL +T++SL +++ + + +DI+ F N +F K + KI K+T Sbjct: 605 MNEKELTKTIKSLL--DVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTP 662 Query: 833 EEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKP--ADLKKRI 890 +E T V +DR+ + AAIVRIMK RK L HN L+ EV +Q + P + +KK I Sbjct: 663 QEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCI 722 Query: 891 ESLIDRDYMERDKENPNQYNYIA 913 E LID+ Y+ER + + ++Y+Y+A Sbjct: 723 EVLIDKQYIERSQASADEYSYVA 745 >gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1 [Homo sapiens] Length = 780 Score = 238 bits (608), Expect = 1e-62 Identities = 209/773 (27%), Positives = 378/773 (48%), Gaps = 81/773 (10%) Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSY--KISANLYKQLRQICEDHIKA 270 ++ W ++ V + S+ K +L+ V +C + K A +++ L++ + IK Sbjct: 16 EDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQ 75 Query: 271 QIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV-LQNSMLPS------ 323 + D+ L LK W+ Q ++ F L+ T + Q S S Sbjct: 76 AQARVLSHQDDTAL-LKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSI 134 Query: 324 IWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLL----RSLLSMLSD-- 377 + + L+ + I S+ ++N+ D + L+ ER GEA D L+ S +++ S+ Sbjct: 135 VRKLMLDTWNESIFSN--IKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPE 192 Query: 378 --LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 435 LQIY+D+FE+ +L+ T R Y + +Q+ V Y+ + + +L+EE R + YL+ Sbjct: 193 DKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETR 252 Query: 436 TQKSLIATVEKQLLGEHLTAILQKGL---NNLLDENRIQDLSLLYQLFSRVRGGVQVLLQ 492 + + + + + + +T+ + L ++ N + L L++ L +V G++ +L+ Sbjct: 253 RECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLK 312 Query: 493 QWIEYIKAFG--------STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAM 544 E+I + G TI + EK V++LL ++ ++ F + +F+ A Sbjct: 313 DLEEHIISAGLADMVAAAETITTDSEK---YVEQLLTLFNRFSKLVKEAFQDDPRFLTAR 369 Query: 545 KEAFETFIN--------------------KRPNKPAELIAKYVDSKLRAG--NKEATDEE 582 +A++ +N + +K EL+A Y D LR +K+ T EE Sbjct: 370 DKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEE 429 Query: 583 LEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECG--AA 640 +E L +++++ +++ KDVF ++K L +RL++ SA + E++M+ L+ E G A Sbjct: 430 IEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLR-EVGMPAD 488 Query: 641 FTSKLEGMFKDMELSKDIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVHL 697 + +KL MF+D+++S+D+ FK+ +N +P + + + IL G W + + V L Sbjct: 489 YVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPAD-SVNIKILNAGAWSRSSEKVFVSL 547 Query: 698 PPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFN 757 P E+ L + FY HSGRKL W + + ++ + + G+ +L+V+ FQ VL +N Sbjct: 548 PTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWN 607 Query: 758 E--GEEFSLEEIKQATGIEDGELRRTLQSLACG---KARVLAKNPK---GKDIEDGDKFI 809 + E+ S E +K AT + D ELRRTL SL K +VL P+ KD +G F Sbjct: 608 QRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFS 667 Query: 810 CNDDFK-----HKLFRIKINQIQMKETVEE--QASTTERVFQDRQYQIDAAIVRIMKMRK 862 N +F R KIN I + E + E + Q R + AI++IMKMRK Sbjct: 668 VNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRK 727 Query: 863 TLSHNLLVSEVYNQLK--FPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913 +S+ L +E+ LK F + +K++IE LI+ Y+ RD+ + N + Y+A Sbjct: 728 KISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 63.2 bits (152), Expect = 1e-09 Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 4/196 (2%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS S DG+D +++ D SS S ++ ++ S+ +++ + +S NSS Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 S SS+SSN + DS++SS S+ D+++ S SS S ++ S + Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961 Query: 123 DTLEFVGFDAKMAEESSSSSSS----SSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178 + D+ ++ S SS+SS SS ++ +S N S S S +N Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021 Query: 179 SSTTVSSFANSKPGSA 194 S+++ SS ++ S+ Sbjct: 1022 SNSSDSSNSSDSSDSS 1037 Score = 60.1 bits (144), Expect = 9e-09 Identities = 51/192 (26%), Positives = 84/192 (43%), Gaps = 1/192 (0%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS S D +D ++ S D SS S ++ ++ S+ N+S + +S NSS Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019 Query: 63 SSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 SS SS+SSN + DS+ SS S+ DS+ S SS S ++ S Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST 181 + + D+ + +SS SS SS + ++ + SS +S + + S+ Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139 Query: 182 TVSSFANSKPGS 193 S ++S S Sbjct: 1140 NSSDSSDSSESS 1151 Score = 57.4 bits (137), Expect = 6e-08 Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 19/205 (9%) Query: 3 SQSSGSGDGNDD-EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKK--RKL 59 S SS S D +D +++ S D SS S S ++ ++ S +D + ++ S+ Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655 Query: 60 NSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKL 119 +S SS+SSNSS+ + DS+ SSSS+ DS+ S SS Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS----------------NSS 699 Query: 120 RFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKS 179 D+ + D+ + +SS+S+SS S ++ +S N S S S + ++ S Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759 Query: 180 STTVSSFANSKPGSAKKLVIKNFKD 204 ++ SS ++ S+ N D Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSD 784 Score = 57.4 bits (137), Expect = 6e-08 Identities = 56/207 (27%), Positives = 95/207 (45%), Gaps = 8/207 (3%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S+SS S D +D +++ S D S+ S S ++ + + S+ N+S + +S +SS Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD--SSDSSNSSDSSDSSDSSNSSDSS 756 Query: 63 SSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 SS SSNSS+ + DS+ SS S+ DS++ S SS S +++S Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS-DSSDSSDS 815 Query: 122 EDTLEFVGFDAKMAEESSSSSSSS----SPTAATSQQQQLKNKSILISSVASVHHANGLA 177 D+ D+ + +SS SS+SS S ++ N+S +S S ++ Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875 Query: 178 KSSTTVSSFANSKPGSAKKLVIKNFKD 204 S ++ SS +N S+ N D Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSD 902 Score = 56.2 bits (134), Expect = 1e-07 Identities = 48/191 (25%), Positives = 82/191 (42%), Gaps = 5/191 (2%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS S D +D +++ S D SS S ++ ++ S+ + S + ++ +S Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SS SS+SSN + DS+ S+ S+ DS++ S S S +S+ Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD-----SSDSSNSSDSSDSSNSS 921 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 D+ E SS+SS SS ++ +S N S +S S + + S+ Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981 Query: 183 VSSFANSKPGS 193 S ++S S Sbjct: 982 SSDSSDSSDSS 992 Score = 55.1 bits (131), Expect = 3e-07 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 8/199 (4%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS S D +D +++ S S S S ++ + + S+ N+S + +S +SS Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617 Query: 63 SSSSSNSSNEREDFDS--------TSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVP 114 SS S S + + + DS +S S+S+ DS+ S SS S ++ S Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677 Query: 115 IQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHAN 174 + D+ + ESS SS SS ++ S N S SS +S + Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737 Query: 175 GLAKSSTTVSSFANSKPGS 193 + S+ S +NS S Sbjct: 738 SNSSDSSDSSDSSNSSDSS 756 Score = 53.9 bits (128), Expect = 7e-07 Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 8/193 (4%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS S D +D ++ S + SS S ++ ++ S+ ++S + +S +SS Sbjct: 747 SDSSNSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 +SS S+ S++ D DS++SS S+ DS++ S SS S + S R + Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS----DSSNRSD 860 Query: 123 DTLEFVGFDAKMAEES--SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180 + D+ + S SS SS S+ ++ +S N S SS +S + + +S Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920 Query: 181 TTVSSFANSKPGS 193 + S +NS S Sbjct: 921 SDSSESSNSSDNS 933 Score = 51.2 bits (121), Expect = 4e-06 Identities = 49/193 (25%), Positives = 85/193 (44%), Gaps = 2/193 (1%) Query: 3 SQSSGSGDGNDD-EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 S SS S D +D +++ S D SS S ++ ++ S+ ++S + +S +S Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114 Query: 62 SSSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 S SS SSNSS+ + DS+ SS S+ DS+ S SS S ++ S Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174 Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180 + + D+ + +SS SS SS + ++ + SS +S + + S Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234 Query: 181 TTVSSFANSKPGS 193 + S ++S S Sbjct: 1235 SDSSDSSDSSDSS 1247 Score = 50.4 bits (119), Expect = 7e-06 Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 6/195 (3%) Query: 3 SQSSGSGD-GNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 S S+G+G+ GNDD + G S S S ++ + ++D + S + +++ + Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD--SD 581 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLG-VSVAASSHVPIQKKLR 120 SS S S+ S++ + DS++SS S+ DS+ S SS S + S K Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641 Query: 121 FEDTLEFVGFDAKMAEESSSSSSS--SSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178 D+ D + +SS+SS+S SS ++ +S + S S S +N Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701 Query: 179 SSTTVSSFANSKPGS 193 S ++ SS ++S S Sbjct: 702 SDSSDSSDSDSSDSS 716 Score = 49.7 bits (117), Expect = 1e-05 Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 4/188 (2%) Query: 3 SQSSGSGDGNDDE-ATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 S SS S D +D ++ S D SS S ++ ++ S+ N+S + +S +S Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SS 1136 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 SS+SS+SS+ E DS+ SS S+ DS+ S SS S ++ S Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST 181 + + D+ + +SS SS SS ++ +S S S S +N S + Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255 Query: 182 TVSSFANS 189 + SS + S Sbjct: 1256 SDSSDSTS 1263 Score = 46.6 bits (109), Expect = 1e-04 Identities = 54/201 (26%), Positives = 82/201 (40%), Gaps = 19/201 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST---------TPPTS 53 S S G N DE SKD G S S A + S T+ + S + Sbjct: 485 SSSRGDASYNSDE---SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD 541 Query: 54 AKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHV 113 + K K +SS S SS+SSN + DS+ S SS DS S S S S +S Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS-------DSNSSSDSDSSDSDSSDSSDSD 594 Query: 114 PIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHA 173 + + D+ + +SS S S SS + + S K+ S +S S ++ Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654 Query: 174 NGLAKSSTTVSSFANSKPGSA 194 + S+++ SS ++ S+ Sbjct: 655 DSSDSSNSSNSSDSSDSSDSS 675 Score = 40.0 bits (92), Expect = 0.010 Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 2/100 (2%) Query: 3 SQSSGSGDGNDDE-ATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 S SS S D +D ++ S D SS S ++ ++ S+ ++S + +S +S Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225 Query: 62 SSSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 S SS S+ SS+ + DS+ SS+S+ DS+ ++ S Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265 Score = 36.6 bits (83), Expect = 0.11 Identities = 40/192 (20%), Positives = 75/192 (39%), Gaps = 7/192 (3%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQE-VRSATDGNTSTTPPTSAKKRKLNSSS 63 S + DG D K P+ S + + S +D N+S+ S + + Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502 Query: 64 SSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFED 123 + S + E +D DSTS ++++ ++ + G + SS D Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562 Query: 124 TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183 + + D+ + SS S SS S ++ +S + + SS +S + S+ Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD------SSDSSDS 616 Query: 184 SSFANSKPGSAK 195 S ++SK S+K Sbjct: 617 SDSSDSKSDSSK 628 >gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens] Length = 822 Score = 62.8 bits (151), Expect = 1e-09 Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 3/189 (1%) Query: 597 IYG-KDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELS 655 IYG KD+F Y+ LA RLL S S + E + LK G A E M KDM S Sbjct: 508 IYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADS 567 Query: 656 KDIMIQFKQYMQNQNVPGNIELTVN--ILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYL 713 + I ++ + + V IL+ +WP + ++ +P ++ E + Y Sbjct: 568 RRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYE 627 Query: 714 GKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGI 773 + R L W+ TLG + E + + V+ Q ++LL F + ++LEE+ +A + Sbjct: 628 QLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKM 687 Query: 774 EDGELRRTL 782 LRR + Sbjct: 688 PVALLRRRM 696 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 56.6 bits (135), Expect = 1e-07 Identities = 34/98 (34%), Positives = 54/98 (55%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SSGS ++E + DGG + + +AA+ S ++S++ +S+ +SS Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS 2633 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 SSSSS+SS+ S+SSSSS+ S+S S+SS Sbjct: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671 Score = 50.1 bits (118), Expect = 1e-05 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 14/153 (9%) Query: 13 DDEATTSKDGGFSSPSPSAAAAAQEVRS------------ATDGNTSTTPPTSAKKRKLN 60 + E+++S G SS S S++++ E T G + + A + Sbjct: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615 Query: 61 SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 SSSSSSS+SS+ S+SSSSS+ S+S S+SS S ++SS Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673 Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ 153 ED+ +A A + S+ ++ PT AT Q Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706 Score = 43.9 bits (102), Expect = 7e-04 Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 38/202 (18%) Query: 18 TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFD 77 T +D G + SP A A Q+ ++ ++S++ +S+ +SSSSSSS S E E+ Sbjct: 2534 TFEDSG-NPKSPDKAQAEQDGAEESESSSSSSSGSSS-----SSSSSSSSGSETEGEEEG 2587 Query: 78 STS------------SSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTL 125 + S++S+ P S+S S+SS S ++SS Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS-------------- 2633 Query: 126 EFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSS 185 + + SSSSSSSSS ++++S + S SS +S + S + Sbjct: 2634 ------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687 Query: 186 FANSKPGSAKKLVIKNFKDKPK 207 + P + L K K K Sbjct: 2688 APTAGPSAQAALPTKATKQAGK 2709 Score = 43.5 bits (101), Expect = 9e-04 Identities = 27/115 (23%), Positives = 56/115 (48%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S + S + +++S SS S S+++++ S++ ++S++ +S+ +SS Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQK 117 SSSSS++++E S ++ P P A+ T + S+H P +K Sbjct: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720 Score = 42.7 bits (99), Expect = 0.002 Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 39/211 (18%) Query: 1 MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTP---------- 50 ++ + G+G + ++ S G P+ ++ ATDG+ + P Sbjct: 2482 LLREDPGAGGWQEPKSLLSL--GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSG 2539 Query: 51 ----PTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVS 106 P A+ + + S SS+SS+ S+SSSSS + + + C G Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC-GTG 2598 Query: 107 ----VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSI 162 AASS A A SSSSSSSSS ++++S + S Sbjct: 2599 GRNCSAASSRA------------------ASPASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640 Query: 163 LISSVASVHHANGLAKSSTTVSSFANSKPGS 193 SS +S ++ + SS++ SS ++S S Sbjct: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 56.2 bits (134), Expect = 1e-07 Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 25/186 (13%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SSG+G + E++T+ G ++ + ++ + + + T+ +ST P+S NS SS Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESST--PSSGANTATNSESS 306 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 ++S+ +N + DS+++SS +S S +TSS G S A +S E + Sbjct: 307 TTSSGANTATNSDSSTTSSGAS--TATNSESSTTSS---GASTATNS----------ESS 351 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 G A A S SS++SS + AT+ ++S +SS AS + + +S+ S Sbjct: 352 TTSSG--ASTATNSGSSTTSSGTSTATN------SESSTVSSGASTATTSESSTTSSGAS 403 Query: 185 SFANSK 190 + NS+ Sbjct: 404 TATNSE 409 Score = 53.5 bits (127), Expect = 9e-07 Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 14/193 (7%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SSG+G + E++T G + + ++ + +AT+ +STT + +SS++ Sbjct: 264 SSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTT 323 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS S+ + +TSS +ST +S S +TSS + + SS Sbjct: 324 SSGASTATNSESSTTSSGAST----ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSE 379 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 V A A S SS++SS + AT+ + SS S + S+T S Sbjct: 380 SSTVSSGASTATTSESSTTSSGASTATNSE----------SSTVSSGASTATNSESSTTS 429 Query: 185 SFANSKPGSAKKL 197 S AN+ S + Sbjct: 430 SGANTATNSGSSV 442 Score = 52.4 bits (124), Expect = 2e-06 Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 9/190 (4%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SSG+ + E++T+ G ++ + ++ + +AT+ +STT ++ SS++ Sbjct: 294 SSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTT 353 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS S+ +TSS +ST +S S + SS + + SS Sbjct: 354 SSGASTATNSGSSTTSSGTST----ATNSESSTVSSGASTATTSESSTTSSGASTATNSE 409 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 V A A S SS++SS AT+ + + +++ +H + A ST VS Sbjct: 410 SSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA--STAVS 467 Query: 185 SFANSKPGSA 194 +KPG + Sbjct: 468 ---EAKPGGS 474 Score = 51.6 bits (122), Expect = 3e-06 Identities = 47/190 (24%), Positives = 89/190 (46%), Gaps = 18/190 (9%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SSG + E++T G ++ + ++ + +AT+ ++STT ++ SS++ Sbjct: 279 SSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTT 338 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS S+ + +TSS +ST +S S +TSS G S A +S E + Sbjct: 339 SSGASTATNSESSTTSSGAST----ATNSGSSTTSS---GTSTATNS----------ESS 381 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 G ESS++SS +S TA S+ + + + ++ S ++G ++ + S Sbjct: 382 TVSSGASTATTSESSTTSSGAS-TATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440 Query: 185 SFANSKPGSA 194 S ++ G+A Sbjct: 441 SVTSAGSGTA 450 Score = 48.5 bits (114), Expect = 3e-05 Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 14/194 (7%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SSG + E++T+ G ++ + ++ + +AT+ ++STT ++ +SS++ Sbjct: 99 SSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTT 158 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS S+ + +TSS +ST + S S+ S SS T Sbjct: 159 SSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTT 218 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 G A S SS++SS + AT+ + SS S S+T S Sbjct: 219 SNGAG----TATNSESSTTSSGASTATNSE----------SSTPSSGAGTATNSESSTTS 264 Query: 185 SFANSKPGSAKKLV 198 S A + S V Sbjct: 265 SGAGTATNSESSTV 278 Score = 48.1 bits (113), Expect = 4e-05 Identities = 39/190 (20%), Positives = 88/190 (46%), Gaps = 3/190 (1%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SS + + E++T+ G ++ + ++ + +AT+ +STT +S NS S Sbjct: 159 SSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT--SSGASTATNSESR 216 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 ++SN + + +S+++SS +S++PS+ + S ++++ E + Sbjct: 217 TTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESS 276 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 G ESS+ SS ++ TA S+ + + ++ S ++G + ++ + S Sbjct: 277 TVSSGISTVTNSESSTPSSGAN-TATNSESSTTSSGANTATNSDSSTTSSGASTATNSES 335 Query: 185 SFANSKPGSA 194 S +S +A Sbjct: 336 STTSSGASTA 345 Score = 46.6 bits (109), Expect = 1e-04 Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 5/191 (2%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 S+G + E T+ G ++ + + + + AT+ +STT ++ SS+ Sbjct: 69 SNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTP 128 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS S+ D +TSS +ST +S S +TSS + + SS Sbjct: 129 SSGASTATNSDSSTTSSGAST----ATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184 Query: 125 LEFVGFDAKMAEES-SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183 V A A S SS++SS + TA S+ + N + ++ S ++G + ++ + Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244 Query: 184 SSFANSKPGSA 194 SS +S G+A Sbjct: 245 SSTPSSGAGTA 255 Score = 46.2 bits (108), Expect = 1e-04 Identities = 44/199 (22%), Positives = 90/199 (45%), Gaps = 21/199 (10%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTT-------------PP 51 SS + + E++T+ G ++ + + + +AT+ +STT P Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248 Query: 52 TSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASS 111 +S NS SS++S+ + + +S++ SS + +S++PS+ + S ++++ Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308 Query: 112 HVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVH 171 + + G A A S SS++SS + AT+ ++S SS AS Sbjct: 309 SSGANTATNSDSSTTSSG--ASTATNSESSTTSSGASTATN------SESSTTSSGASTA 360 Query: 172 HANGLAKSSTTVSSFANSK 190 +G + +S+ S+ NS+ Sbjct: 361 TNSGSSTTSSGTSTATNSE 379 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 51.2 bits (121), Expect = 4e-06 Identities = 60/202 (29%), Positives = 88/202 (43%), Gaps = 14/202 (6%) Query: 3 SQSSGSGDGNDDEATTSKDGG-----FSSPSPSAAAAAQEVRSATDGNTSTTPPTS---A 54 SQS SG ATT+ G S P+P + A+ G + + A Sbjct: 2472 SQSLSSGA----VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527 Query: 55 KKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVP 114 K+R+ +SSSSSSS+SS+ S+SSSS + S+ P L V + + P Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL-KRVPSPTPAP 2586 Query: 115 IQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHAN 174 ++ +R E K SSSSSSSSS ++++S + S SS +S ++ Sbjct: 2587 -KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645 Query: 175 GLAKSSTTVSSFANSKPGSAKK 196 + S A KP S KK Sbjct: 2646 SSSPSPAKPGPQALPKPASPKK 2667 Score = 36.6 bits (83), Expect = 0.11 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 7/146 (4%) Query: 6 SGSGDGNDDEATTSKDGGF---SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 SGS G D T G SSP P A RS + + +R+ + S Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP-STSSFCLGVSVAASSHVPIQKKLRF 121 SS + R S S S+ L + SASP S A + P++++ R Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSP 147 + E D+K S S SSP Sbjct: 1580 GSSPE---VDSKSRLSPRRSRSGSSP 1602 Score = 36.6 bits (83), Expect = 0.11 Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNT-STTPPTSAKKRKLNS 61 S SS G G E ++S + P P + A + RS+ + T S TPP R Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 + + S R S + S TP PR SPS SS Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTP---PRHRRSPSVSS 1732 Score = 36.2 bits (82), Expect = 0.14 Identities = 24/87 (27%), Positives = 43/87 (49%) Query: 10 DGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNS 69 +G E T +K SS S S+++++ S++ ++S++ +S+ +SSSSSS + Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651 Query: 70 SNEREDFDSTSSSSSTPPLQPRDSASP 96 + +S PP R S SP Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSP 2678 Score = 35.4 bits (80), Expect = 0.24 Identities = 42/196 (21%), Positives = 72/196 (36%), Gaps = 23/196 (11%) Query: 6 SGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65 SGS D ++ S S SP + A G+ S+ P + R L S S Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638 Query: 66 SSNSSNEREDFDSTSSSSSTPPLQP---------RDSASPSTSSFCLGVSVAASSHVPIQ 116 S+S + +SS+ S+P P R S P T S ++ S + Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698 Query: 117 KKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGL 176 +K R S S+SSS T + + + ++ S+ A ++ Sbjct: 1699 RKARL--------------SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744 Query: 177 AKSSTTVSSFANSKPG 192 +S+++ + S+ G Sbjct: 1745 RRSASSPRTKTTSRRG 1760 Score = 35.0 bits (79), Expect = 0.32 Identities = 47/186 (25%), Positives = 65/186 (34%), Gaps = 13/186 (6%) Query: 27 PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 86 P+P VR ++ + T KK+K S SS+ ER+ S Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222 Query: 87 PLQPRDSASPSTSSFCLGVS---VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 143 + R SP+ S + S P K R + A A S +S S Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST-----SADSASSSDTSRS 277 Query: 144 SSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST--TVSSFANSKPGSAKKLVIKN 201 S AA + L +S S AS G A S T S+ S P +A K Sbjct: 278 RSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334 Query: 202 FKDKPK 207 ++DK K Sbjct: 335 YEDKDK 340 Score = 34.7 bits (78), Expect = 0.42 Identities = 35/183 (19%), Positives = 69/183 (37%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S+ S + ++ T++ G SSP P + R ++ + T +R ++S Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SS + S S S SS P + R S ++S + + P K + Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 + + S SS T+ Q+ + +++ S +H+ A+ ++ Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831 Query: 183 VSS 185 +S Sbjct: 1832 RTS 1834 Score = 32.7 bits (73), Expect = 1.6 Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 7/140 (5%) Query: 25 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84 SSP P + +S ++S++P K S +S +NE+ S Sbjct: 819 SSPPPKQKSKTPSRQS----HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874 Query: 85 TPPLQPRDSASPSTSSFCLGVSV--AASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 142 + P S +PS S C G S SS P Q R V + S S S Sbjct: 875 SSPDPELKSRTPSRHS-CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933 Query: 143 SSSSPTAATSQQQQLKNKSI 162 SS SP+ TS+ +++S+ Sbjct: 934 SSPSPSRVTSRTTPRRSRSV 953 >gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] Length = 2517 Score = 47.4 bits (111), Expect = 6e-05 Identities = 69/301 (22%), Positives = 123/301 (40%), Gaps = 72/301 (23%) Query: 560 AELIAKYVDSKLRAGNKEATDE-----ELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 614 +E A+Y+D +++ G +L++ L+ IM++ FE FY+ +A R Sbjct: 1546 SEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELAT-TFEHFYQHYMADR 1604 Query: 615 LLVGKSASVDAEKSMLSKLKHECGAAFTSKL-EGMFKDMELSKDIMIQFKQYM------- 666 LL S+ ++ + + G F ++L + M + + S+++ QF + Sbjct: 1605 LLSFGSSWLEGA------VLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKL 1658 Query: 667 ---QNQNVPGNIE-----------------------LTVNILTMGYWPT------YVPME 694 Q +E +++ +L+ WP Y P + Sbjct: 1659 FLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRK 1718 Query: 695 VHLPPEMVKLQEIFKTFY----------LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQ 744 LP E + F +FY +G H R+LQW + LG +AE + GK+ L Sbjct: 1719 C-LPTEFCDALDRFSSFYSQSQNHPVLDMGPH--RRLQW-TWLG----RAELQFGKQILH 1770 Query: 745 VSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIED 804 VS Q +LL FN+ EE S+E + + + + L + L L G + +G+D Sbjct: 1771 VSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLH--EGQDFPH 1828 Query: 805 G 805 G Sbjct: 1829 G 1829 >gi|40807452 peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Homo sapiens] Length = 1664 Score = 46.2 bits (108), Expect = 1e-04 Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Query: 14 DEATTSKDGGFSSP--SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS------SSSS 65 D T+S+ S+P +PS+ + + D NT T P SAK+R + S+S Sbjct: 1355 DHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASP 1414 Query: 66 SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTL 125 SS R +S S SS + S+S S+SS S + S P K+ R Sbjct: 1415 SSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLS---PPHKRWRRSSCS 1471 Query: 126 EFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKS 161 ++ SSSSSSSSS ++++S + +++S Sbjct: 1472 S--SGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRS 1505 Score = 39.7 bits (91), Expect = 0.013 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 16/134 (11%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPP----------T 52 S SS G + S G + S ++++++ S+ + S +PP + Sbjct: 1413 SPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSS 1472 Query: 53 SAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSH 112 S + R+ +SSSSSSS+SS+ S+ S S +P + R SS+ + H Sbjct: 1473 SGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRSDRRRRYSSY------RSHDH 1526 Query: 113 VPIQKKLRFEDTLE 126 Q+ L+ E +E Sbjct: 1527 YQRQRVLQKERAIE 1540 >gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sapiens] Length = 2881 Score = 44.7 bits (104), Expect = 4e-04 Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 29/139 (20%) Query: 48 TTPPTSAKKR--KLNSSSSSSSNSSNEREDFD--STSSSSSTPPLQPRDSASPSTSSFCL 103 T P S K R K S SSS S+S +ER S+SSSSS+ R +S S+SS C Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172 Query: 104 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSIL 163 S ++SS SSSSSSSSS + + +++ K +S Sbjct: 2173 SASSSSSS----------------------STSSSSSSSSSSSEESDSDEEEAQKRES-- 2208 Query: 164 ISSVASVHHANGLAKSSTT 182 ++ + +A STT Sbjct: 2209 -TTHMKAYDEESVASLSTT 2226 Score = 39.7 bits (91), Expect = 0.013 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Query: 4 QSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSS 63 + S S +D ++ S SS S S+++ + ++ ++S+ S+ SSS Sbjct: 2126 RGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSS 2185 Query: 64 SSSSNSSNEREDFDSTSSS--SSTPPLQPRDSASPSTSS 100 SSSS+SS+E D D + ST ++ D S ++ S Sbjct: 2186 SSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLS 2224 Score = 37.7 bits (86), Expect = 0.049 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 4/127 (3%) Query: 28 SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPP 87 +P+ A+ V ++S + S + + SSSSSS+SS S+SSSSS+ Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172 Query: 88 LQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSP 147 S+S ++SS S + S ++ + E T +D EES +S S++ Sbjct: 2173 SASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYD----EESVASLSTTQD 2228 Query: 148 TAATSQQ 154 S Q Sbjct: 2229 ETQDSFQ 2235 Score = 33.1 bits (74), Expect = 1.2 Identities = 21/74 (28%), Positives = 38/74 (51%) Query: 20 KDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDST 79 K G SS + + S + ++S++ + ++ +SSSSS S++S+ S+ Sbjct: 2125 KRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSS 2184 Query: 80 SSSSSTPPLQPRDS 93 SSSSS+ + DS Sbjct: 2185 SSSSSSSSSEESDS 2198 >gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial [Homo sapiens] Length = 909 Score = 44.3 bits (103), Expect = 5e-04 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 19/185 (10%) Query: 17 TTSKDGGFSSPSPSAAAAAQEVRS-ATDGNTS---TTPPTSAKKRKLNSSSSSSSNSSNE 72 TT++ S+PS S++ E S +T G TS TT TS SS +++ +S++ Sbjct: 172 TTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHD 231 Query: 73 REDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDA 132 F S+ ++S TP ++PS++S + S + +T Sbjct: 232 TPSFTSSITTSETP-----SHSTPSSTSLITTTKTTSHSTPSFTSSITTTET-------- 278 Query: 133 KMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPG 192 S+ S +SS T T+ S + ++ + H S TT + ++S P Sbjct: 279 --TSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPS 336 Query: 193 SAKKL 197 + + Sbjct: 337 FSSSI 341 Score = 36.2 bits (82), Expect = 0.14 Identities = 42/185 (22%), Positives = 72/185 (38%), Gaps = 19/185 (10%) Query: 15 EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST------TPP--TSAKKRKLNSSSSSS 66 E T+ F+S + + S T NT T TP TS + SSS+ S Sbjct: 124 ETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPS 183 Query: 67 SNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLE 126 +SS + S S+ T + ++ S ST SF ++ ++ DT Sbjct: 184 FSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTS---------HDTPS 234 Query: 127 FVG--FDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184 F ++ S+ SS+S T T+ S + ++ + H A+ S TT Sbjct: 235 FTSSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTE 294 Query: 185 SFANS 189 + +++ Sbjct: 295 TTSHN 299 >gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 [Homo sapiens] Length = 559 Score = 42.0 bits (97), Expect = 0.003 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 12/170 (7%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S+ G G +E F P + E S G PP K ++ Sbjct: 230 SRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPAT 289 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTS--------SFCLGVSVAASSHVP 114 + S S+ +++ S+ S S P PR S+S S S S G V A S Sbjct: 290 ADSPKPSAKKQKK-SSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPR 348 Query: 115 IQKK---LRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKS 161 KK + ++ + F ++ A+ S S+SSSSS +++ S + +N S Sbjct: 349 EAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHS 398 Score = 37.0 bits (84), Expect = 0.084 Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 18/138 (13%) Query: 14 DEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNER 73 D+++T + + P A A EV + + ++ SA+ NSSSSS S+S ++ Sbjct: 332 DKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDF 391 Query: 74 EDFDSTSSS---SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGF 130 E + S S LQ +S +SS G A ++ +L F D+ Sbjct: 392 EPSQNHSQGPLRSMVEDLQSEESDEDDSSS---GEEAAGKTNPGRDSRLSFSDS------ 442 Query: 131 DAKMAEESSSSSSSSSPT 148 ES +S+ SS P+ Sbjct: 443 ------ESDNSADSSLPS 454 >gi|28559039 mediator complex subunit 1 [Homo sapiens] Length = 1581 Score = 42.0 bits (97), Expect = 0.003 Identities = 47/194 (24%), Positives = 79/194 (40%), Gaps = 25/194 (12%) Query: 15 EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNERE 74 E + + S P + + + DG + PP K++K ++ S S+SS+ R Sbjct: 974 EGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPP---KRKKADTEGKSPSHSSSNRP 1030 Query: 75 DFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQ------------KKLRFE 122 TS+ S P S +P GV+ + IQ ++ Sbjct: 1031 FTPPTSTGGSKSPGSAGRSQTPP------GVATPPIPKITIQIPKGTVMVGKPSSHSQYT 1084 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAA--TSQQQQLKNKSILISSVASVHHANGLAKSS 180 + +K SSSSSSS+ T+ S + + + S L SS+ S ++G ++S Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144 Query: 181 TTVSSFANSKPGSA 194 SS + KPGS+ Sbjct: 1145 N--SSQSGGKPGSS 1156 Score = 36.2 bits (82), Expect = 0.14 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 31/204 (15%) Query: 8 SGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSS 67 SG G + TS G S S ++ G+ S P S+ +SSS SSS Sbjct: 1227 SGSGGSHMSGTSSSSGMKSSSGLGSS----------GSLSQKTPPSSNSCTASSSSFSSS 1276 Query: 68 NSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF-----------------CLGVSVAAS 110 SS SS +P + S + +GVS +S Sbjct: 1277 GSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSS 1336 Query: 111 SHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASV 170 SH P+ K EF G K ++ S S+S S + S ++ ++K++ + VA + Sbjct: 1337 SH-PMSSKHNMSGG-EFQGKREKSDKDKSKVSTSGS--SVDSSKKTSESKNVGSTGVAKI 1392 Query: 171 HHANGLAKSSTTVSSFANSKPGSA 194 + S + + KPG + Sbjct: 1393 IISKHDGGSPSIKAKVTLQKPGES 1416 Score = 35.4 bits (80), Expect = 0.24 Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 19/206 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSA-TDGNTST--------TPPTS 53 S S + G+ + + SS S S+A+ + +++S+ ++G++S+ + +S Sbjct: 1079 SHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS 1138 Query: 54 AKKRKLNSSSSSSSNSSNEREDFDSTSSSSST---PPLQPRDSASPSTSSFCLGVSVAAS 110 + NSS S S+ +S SSST P +P +PS S +++ S Sbjct: 1139 GSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSK----PNISPS 1194 Query: 111 SHVPIQKKLRFEDTLEFVGF--DAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVA 168 P + ++ V + A+ SS S S + TS +K+ S L SS Sbjct: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS-G 1253 Query: 169 SVHHANGLAKSSTTVSSFANSKPGSA 194 S+ + +S T SS + S GS+ Sbjct: 1254 SLSQKTPPSSNSCTASSSSFSSSGSS 1279 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 42.0 bits (97), Expect = 0.003 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 18/197 (9%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SS D TS S+P S + V S+ N STTP S + ++ +S Sbjct: 431 SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124 SS ++ ST S STP S P SS + S P+ DT Sbjct: 491 SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS-----EASTLSTTPV-------DT 538 Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANGLAK 178 V ++ + S++ +S PT+ S+ + + ++ S ++ + Sbjct: 539 STPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN 598 Query: 179 SSTTVSSFANSKPGSAK 195 + T SS A+S +A+ Sbjct: 599 TFVTTSSEASSSSTTAE 615 Score = 40.4 bits (93), Expect = 0.008 Identities = 48/194 (24%), Positives = 84/194 (43%), Gaps = 12/194 (6%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS + +G +T +G S+P + + + V S+ TSTTP S N+ Sbjct: 549 SSSSTTPEGTSIPTSTPSEG--STPLTNMPVSTRLVVSSEASTTSTTPADS------NTF 600 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAAS-SHVPIQKKLRF 121 ++SS +S+ + TS +ST + S S S+ + S A++ S P+ Sbjct: 601 VTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPV 660 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS- 180 + E + E +S +S+ +T N +++ SS AS + S+ Sbjct: 661 TTSTE--ATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTP 718 Query: 181 TTVSSFANSKPGSA 194 T S+ A+S P +A Sbjct: 719 VTTSTEASSSPTTA 732 Score = 40.0 bits (92), Expect = 0.010 Identities = 40/193 (20%), Positives = 78/193 (40%), Gaps = 8/193 (4%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + +G +T +G S+P S A+ V ++ S TP ++ ++ Sbjct: 313 SSSPTTAEGTSIPTSTYTEG--STPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SS ++ ST S STP + P ++ + +S +P+ K F Sbjct: 371 PSSLPTTAEATSMLTSTLSEGSTPL-----TNMPVSTILVASSEASTTSTIPVDSK-TFV 424 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 T AE++S ++S+ S + + + S +++ +K+ T Sbjct: 425 TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484 Query: 183 VSSFANSKPGSAK 195 S+ A+S P +A+ Sbjct: 485 TSTEASSSPPTAE 497 Score = 38.5 bits (88), Expect = 0.029 Identities = 39/193 (20%), Positives = 81/193 (41%), Gaps = 8/193 (4%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SS + DG +T +G S+P S + + V S+ + +T +T P S+ Sbjct: 1080 SSSSTTADGTSMPTSTYSEG--STPLTSVPVSTRLVVSS-EASTLSTTPVDTSIPVTTST 1136 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 +SSS ++ E ++ S T PL ++ P +++ + S P+ K + Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPL----ASMPVSTTLVVSSEANTLSTTPVDSKTQVA 1192 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 + E AE +S +S+ + +++ + S +++ + + T Sbjct: 1193 TSTE-ASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVT 1251 Query: 183 VSSFANSKPGSAK 195 S+ +S P +A+ Sbjct: 1252 TSAETSSSPTTAE 1264 Score = 38.5 bits (88), Expect = 0.029 Identities = 47/200 (23%), Positives = 84/200 (42%), Gaps = 20/200 (10%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 +S S+ S +G +T +G S+P S + + + S+ STTP ++ ++ Sbjct: 2552 ISSSATSAEGTSMPTSTYSEG--STPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTST 2609 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 +SSS ++ + ST S ST S P SS + S P+ Sbjct: 2610 ETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASS-----EASTLSTTPV------ 2658 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQ-----LKNKSILISSVASVHHANGL 176 DT V + +++ SS PT+ ++ L + ++L +S AS + Sbjct: 2659 -DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPV 2717 Query: 177 AKSS-TTVSSFANSKPGSAK 195 S+ T S+ A+S P +A+ Sbjct: 2718 DTSTPVTTSAEASSSPTTAE 2737 Score = 38.5 bits (88), Expect = 0.029 Identities = 43/196 (21%), Positives = 75/196 (38%), Gaps = 8/196 (4%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SS TS G S+P + + + ++ STTP ++ ++ +S Sbjct: 2671 SSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEAS 2730 Query: 65 SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVS-VAASSHVPIQKKLRFED 123 SS ++ ST S STP S P SS VS A + +P+ Sbjct: 2731 SSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV-------T 2783 Query: 124 TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183 T AE +S +S+ S T+ + + + S ++ + T Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTT 2843 Query: 184 SSFANSKPGSAKKLVI 199 S+ A+S P +A+ +V+ Sbjct: 2844 STKASSSPTTAEGIVV 2859 Score = 38.1 bits (87), Expect = 0.038 Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 30/200 (15%) Query: 17 TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTT----PPTSAKKRKLNSSSSSSSNSSNE 72 TTS + SSP P+A + + ++G+T T T + ++ S++ +++S Sbjct: 1015 TTSTEA--SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTP 1072 Query: 73 REDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE---DTLEFVG 129 + SSSS+T D S TS++ G + S VP+ +L TL Sbjct: 1073 VTTYSQASSSSTT-----ADGTSMPTSTYSEGSTPLTS--VPVSTRLVVSSEASTLSTTP 1125 Query: 130 FDAKMAEESSSSSSSSSPTA-------------ATSQQQQLKNKSILISSVASVHHANGL 176 D + +S+ +SSS TA T + ++++SS A+ + Sbjct: 1126 VDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPV 1185 Query: 177 -AKSSTTVSSFANSKPGSAK 195 +K+ S+ A+S P +A+ Sbjct: 1186 DSKTQVATSTEASSPPPTAE 1205 Score = 38.1 bits (87), Expect = 0.038 Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 8/193 (4%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + +G +T +G S+P S + V S+ STTP ++ S Sbjct: 3260 SSSPPTAEGTSMPTSTPSEG--STPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQ 3317 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 +SSS ++ ST S STP S +P SS + S P+ Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS-----EASTLSTTPVDTSTPVT 3372 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 + E AE +S +SS S + ++ S V ++ + + T Sbjct: 3373 TSTE-ASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVT 3431 Query: 183 VSSFANSKPGSAK 195 S+ A+S P A+ Sbjct: 3432 TSTEASSSPTIAE 3444 Score = 37.4 bits (85), Expect = 0.064 Identities = 45/209 (21%), Positives = 81/209 (38%), Gaps = 40/209 (19%) Query: 17 TTSKDGGFSSPSPSAAAAAQEVRSATDGNT--------------------STTPPTSAKK 56 TTS + SSP P+A + ++++GNT STTP ++ Sbjct: 2311 TTSTEA--SSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP 2368 Query: 57 RKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQ 116 S + SS ++++ ST S STP S P SS + S P+ Sbjct: 2369 VTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS-----EASTHSTTPV- 2422 Query: 117 KKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASV 170 DT V + + +++ +S PT+ S+ + ++ S ++ Sbjct: 2423 ------DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTL 2476 Query: 171 HHANGLAKSSTTVSSFANSKPGSAKKLVI 199 + T S+ A+S P +A+ +V+ Sbjct: 2477 STTPVDTSTPMTTSTEASSSPTTAEDIVV 2505 Score = 35.4 bits (80), Expect = 0.24 Identities = 21/72 (29%), Positives = 38/72 (52%) Query: 27 PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 86 PS ++ +V AT G ST TS + ++SSSS++ S + ++F + + +++ P Sbjct: 3942 PSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP 4001 Query: 87 PLQPRDSASPST 98 S +PST Sbjct: 4002 LTYVTMSTAPST 4013 Score = 34.3 bits (77), Expect = 0.54 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 13/178 (7%) Query: 37 EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 96 E+ S TS TP S+ + S ++S ++S+ F S++ +S+P Sbjct: 90 EMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPM 149 Query: 97 ST-SSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQ 155 ST S + ++A S P+ + V + + +SSS ++P + T + Sbjct: 150 STPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKS 209 Query: 156 QLKNKSILISS-------VASVHHANGLA-----KSSTTVSSFANSKPGSAKKLVIKN 201 S ++S VAS L + T+S+ A+S P +A+ + N Sbjct: 210 TNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267 Score = 34.3 bits (77), Expect = 0.54 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 29/191 (15%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S +G +T+ +G S+P + V S+ STTP ++ +S Sbjct: 3437 SSSPTIAEGTSLPTSTTSEG--STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSP 3494 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 ++SS ++ ST+ STP S +P SS + S P+ Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS-----EASTLSTTPV------- 3542 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 D+ FV +SSS +SSSP ++ S SS+ + + SST Sbjct: 3543 DSNTFV---------TSSSQASSSPATLQVTTMRMSTPSEGSSSLTT------MLLSSTY 3587 Query: 183 VSSFANSKPGS 193 V+S S P + Sbjct: 3588 VTSSEASTPST 3598 Score = 33.5 bits (75), Expect = 0.93 Identities = 38/165 (23%), Positives = 62/165 (37%), Gaps = 6/165 (3%) Query: 25 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84 S+P + + V S+ TST P S S +SSS ++ + ST S S Sbjct: 392 STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGS 451 Query: 85 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 144 TP S +P SS +S P+ K + + E AE +S +S+ Sbjct: 452 TPLTSMPVSTTPVASSEASNLST-----TPVDSKTQVTTSTE-ASSSPPTAEVNSMPTST 505 Query: 145 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANS 189 S + + + S +++ + T SS A+S Sbjct: 506 PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550 Score = 32.7 bits (73), Expect = 1.6 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 21/115 (18%) Query: 41 ATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 +++GNT +T P +K + NS+ +SSS ++ + +S + S P SP +S Sbjct: 2058 SSEGNTLSTTPVDSKTQVTNSTEASSSATA------EGSSMTISAP-----SEGSPLLTS 2106 Query: 101 FCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSS-SSSSSPTAATSQQ 154 L + AS TL D+ +S+ SSS PT TS Q Sbjct: 2107 IPLSTTPVASPEA---------STLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQ 2152 Score = 32.3 bits (72), Expect = 2.1 Identities = 38/165 (23%), Positives = 66/165 (40%), Gaps = 16/165 (9%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 +S S +G +T +G S+ S + V S+ + STTP ++ S Sbjct: 1492 VSSSPTPAEGTSIAISTPSEG--STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYS 1549 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 +SSS +++ ST S STP ++ P ++ + S PI K + Sbjct: 1550 QASSSPTTADGTSMQTSTYSEGSTPL-----TSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISS 166 + E SS+++ SS T +T + SI +S+ Sbjct: 1605 TASTE---------ASSSTTAEGSSMTISTPSEGSPLLTSIPVST 1640 Score = 32.3 bits (72), Expect = 2.1 Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 18/198 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 + S + +G +T +G ++P S + V ++ STTP S ++ Sbjct: 2258 TSSPTTAEGTSIPTSTLSEG--TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315 Query: 63 SSSSSNSSNEREDFDSTSSSSSTP----PLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 118 +SS ++ STSS +TP P+ AS TS+ + A + P+ Sbjct: 2316 ASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS---TTPADTSTPV--- 2369 Query: 119 LRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178 T G A+++S +S+ S + + + +SS AS H + Sbjct: 2370 ----TTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPV-VSSEASTHSTTPVDT 2424 Query: 179 SS-TTVSSFANSKPGSAK 195 S+ T S+ A+S P +A+ Sbjct: 2425 STPVTTSTEASSSPTTAE 2442 Score = 32.3 bits (72), Expect = 2.1 Identities = 38/151 (25%), Positives = 58/151 (38%), Gaps = 14/151 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + +G +T +G S+P S + V STTP S ++ Sbjct: 3025 SSSPTTAEGTGIPISTPSEG--STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SSS + ST S STP S +P TSS +++ S P+ Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSS-----AISTLSTTPV------- 3130 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQ 153 DT V + ++S +S PT+ S+ Sbjct: 3131 DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161 Score = 32.0 bits (71), Expect = 2.7 Identities = 41/183 (22%), Positives = 72/183 (39%), Gaps = 17/183 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + DG +G S+P S + V S+ STTP ++ ++ Sbjct: 1964 SSSPTTADGTSMPTPAYSEG--STPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SSS ++ ST S +TP + P +++ + S P+ K + Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPL-----AGMPVSTTLVVSSEGNTLSTTPVDSKTQVT 2076 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182 ++ E A S+++ SS +A S+ L L ++ + A+ L S+T Sbjct: 2077 NSTE--------ASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL--STTP 2126 Query: 183 VSS 185 V S Sbjct: 2127 VDS 2129 Score = 32.0 bits (71), Expect = 2.7 Identities = 51/214 (23%), Positives = 83/214 (38%), Gaps = 19/214 (8%) Query: 3 SQSSGSGDGNDDEAT-TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 SQ+ S DD + TS S+P S + V S+ STTP ++ ++ Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTST 2432 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVA-ASSHVPIQKKLR 120 +SSS ++ S S +TP S +P SS +S + P+ Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE 2492 Query: 121 FED---TLEFVGFDAKMAEESS--------SSSSSSSPTAATSQQQQLKNKSILISSV-- 167 T E + A E S S++ +SP A+T + + S +++S Sbjct: 2493 ASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEI 2552 Query: 168 -ASVHHANGLAKSSTTVSSFA---NSKPGSAKKL 197 +S A G + ++T S + S P S K L Sbjct: 2553 SSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586 Score = 31.6 bits (70), Expect = 3.5 Identities = 42/200 (21%), Positives = 77/200 (38%), Gaps = 20/200 (10%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 +S S +G +T +G +P S + V ++ STTP ++ ++ Sbjct: 843 VSSSPTPAEGTSMPTSTYSEG--RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST 900 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 + SS +S ST STP DS +P SS S P+ Sbjct: 901 EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSS-----EARTLSATPV------ 949 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGL----- 176 DT V + +++ +S PT+ S+ + + ++ + A+ L Sbjct: 950 -DTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPV 1008 Query: 177 -AKSSTTVSSFANSKPGSAK 195 + + T S+ A+S P +A+ Sbjct: 1009 DSNTPLTTSTEASSPPPTAE 1028 Score = 31.6 bits (70), Expect = 3.5 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 25/179 (13%) Query: 32 AAAAQEVRSAT--DGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPL- 88 A++A + S T D +T T T A S +S NS+ TS ST P+ Sbjct: 1350 ASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVV 1409 Query: 89 ---------QPRDSASPSTSS--FCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEE 137 P D+++P T+S + A +P + L+ + Sbjct: 1410 SSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469 Query: 138 SSSSSSSSSP----------TAATSQQQQLKNKSILISSVASVHHA-NGLAKSSTTVSS 185 S +S+ S++P TA +S + SI IS+ + A + S+TTV+S Sbjct: 1470 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528 Score = 31.6 bits (70), Expect = 3.5 Identities = 35/199 (17%), Positives = 80/199 (40%), Gaps = 20/199 (10%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 + SS + +G+ + +G SP ++ + ++ + +T +T P + + S+ Sbjct: 2081 ASSSATAEGSSMTISAPSEG---SPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITST 2137 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SSS E +++ S PL ++ P +++ +++ S P+ Sbjct: 2138 EVSSSPIPTEGTSMQTSTYSDRRTPL----TSMPVSTTVVASSAISTLSTTPV------- 2186 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANGL 176 DT V + ++S +S PT+ S+ + ++ S +++ Sbjct: 2187 DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVD 2246 Query: 177 AKSSTTVSSFANSKPGSAK 195 + T S+ A S P +A+ Sbjct: 2247 TSTPVTTSTEATSSPTTAE 2265 Score = 31.2 bits (69), Expect = 4.6 Identities = 39/198 (19%), Positives = 81/198 (40%), Gaps = 10/198 (5%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + +G +T+ +G S ++ + + ++ + +T T P K + S+ Sbjct: 1257 SSSPTTAEGTSLPTSTTSEG---STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN 1313 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122 SSS + E +++ S PL ++ P ++ +++ S P+ Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPL----TSIPVNTTLVASSAISILSTTPVDNSTPVT 1369 Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST- 181 + E + E +S +S+ T + + ++SS AS A + S+ Sbjct: 1370 TSTE--ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG 1427 Query: 182 TVSSFANSKPGSAKKLVI 199 T S+ A S P +A+ + I Sbjct: 1428 TTSAEATSSPTTAEGISI 1445 Score = 31.2 bits (69), Expect = 4.6 Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 20/200 (10%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 +S S +G +T +G +P S V S+ STTP ++ ++ Sbjct: 1668 VSSSPTPAEGTSMPTSTYTEG--RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTST 1725 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 + SS +S +ST S +TP S +P SS + S PI Sbjct: 1726 EARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSS-----EASTLSATPI------ 1774 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ-----QQQLKNKSILISSVASVHHANGL 176 DT V + +++ +S PT+ S+ + +++ +S AS + Sbjct: 1775 -DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833 Query: 177 AKSSTTVSSFA-NSKPGSAK 195 +S V+S A +S P A+ Sbjct: 1834 DSNSPVVTSTAVSSSPTPAE 1853 Score = 31.2 bits (69), Expect = 4.6 Identities = 37/154 (24%), Positives = 58/154 (37%), Gaps = 23/154 (14%) Query: 17 TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDF 76 +T+ +G S+ S + V S STTP S ++ SSS+ S+ Sbjct: 2508 STASEG--STLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565 Query: 77 DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAE 136 ST S STP S P SS + S P+ + Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASS-----EASTLSTTPVDTSI----------------P 2604 Query: 137 ESSSSSSSSSPTAATSQQQQLKNKSILISSVASV 170 ++S+ +SSSPT A + S + +S+ S+ Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSI 2638 Score = 31.2 bits (69), Expect = 4.6 Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 16/195 (8%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64 SS + +G +T +G +P S + V S+ STTP S ++ +S Sbjct: 3203 SSTTAEGTSIPTSTPSEG--MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260 Query: 65 SSSNSSNEREDFDSTSSSSSTP----PLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 SS ++ ST S STP P+ AS TS+ + A + P+ Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS---TTPADTSTPV----- 3312 Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180 T +A+ +S +S+ S + ++ S +++ + Sbjct: 3313 --TTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTP 3370 Query: 181 TTVSSFANSKPGSAK 195 T S+ A+ P +A+ Sbjct: 3371 VTTSTEASLSPTTAE 3385 Score = 30.8 bits (68), Expect = 6.0 Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 18/198 (9%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 + SS + +G+ +T +G SP ++ + ++ + +T +T P + + S+ Sbjct: 1610 ASSSTTAEGSSMTISTPSEG---SPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITST 1666 Query: 63 SSSSSNSSNEREDF-DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 SSS + E ST + TP +P SS +++ S P+ Sbjct: 1667 EVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS-----AISTLSTTPVDNSTPV 1721 Query: 122 EDTLEFVGFDAKMAEESSSSSS--SSSPTAATSQQQQLK-NKSILISSVASVHHANGLAK 178 + E A+ + +S +S +S+P+ T+ + + + ++SS AS A + Sbjct: 1722 TTSTE-----ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDT 1776 Query: 179 SS-TTVSSFANSKPGSAK 195 S+ T S+ A S P +A+ Sbjct: 1777 STPVTTSTEATSSPTTAE 1794 Score = 30.8 bits (68), Expect = 6.0 Identities = 48/205 (23%), Positives = 85/205 (41%), Gaps = 32/205 (15%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S S + +G +T+ +G S+ S + V S+ STTP Sbjct: 2848 SSSPTTAEGIVVPISTASEG--STLLTSIPVSTTPVASSEASTLSTTP----------VD 2895 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAAS-----SHVPIQK 117 +S +S E +T+ +S P P + ++P TS V VA S S P+ Sbjct: 2896 TSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV-- 2953 Query: 118 KLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQ-QLKNKSILISSVASVHHANGL 176 DT V A+ + +++ +S P + +++ L + S+ VAS A+ L Sbjct: 2954 -----DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS-SEASTL 3007 Query: 177 AK------SSTTVSSFANSKPGSAK 195 ++ + T S+ A+S P +A+ Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAE 3032 Score = 30.4 bits (67), Expect = 7.9 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 + SS + +G +T +G S+P S V S+ STTP ++ ++ Sbjct: 667 TSSSTTAEGTSMPTSTYTEG--STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTE 724 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 +SSS +++ ST S STP S + TSS Sbjct: 725 ASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762 Score = 30.4 bits (67), Expect = 7.9 Identities = 40/200 (20%), Positives = 76/200 (38%), Gaps = 21/200 (10%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 +S S +G +T +G S+P + V S+ STTP ++ ++ Sbjct: 3083 VSSSPTPAEGTSMPISTYSEG--STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST 3140 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121 + SS +S ST S STP + P ++ + + S P+ Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPL-----TYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195 Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANG 175 + E A S+++ +S PT+ S+ + N + S + + Sbjct: 3196 TTSTE--------ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247 Query: 176 LAKSSTTVSSFANSKPGSAK 195 + + T S+ A+S P +A+ Sbjct: 3248 DSNTPLTTSTEASSSPPTAE 3267 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 41.6 bits (96), Expect = 0.003 Identities = 26/75 (34%), Positives = 40/75 (53%) Query: 26 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 85 S + + + + R+ T + S + +S+ SSSS SS+SS S+SSSSST Sbjct: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613 Query: 86 PPLQPRDSASPSTSS 100 RDS+S ++SS Sbjct: 614 SGSSSRDSSSSTSSS 628 Score = 38.1 bits (87), Expect = 0.038 Identities = 25/68 (36%), Positives = 45/68 (66%), Gaps = 6/68 (8%) Query: 18 TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFD 77 TSK SS S S+++++ S++ G++S++ +S++ +SSSSSS++ S+ R+ Sbjct: 570 TSKSRSRSSSSSSSSSSST---SSSSGSSSSSGSSSSRS---SSSSSSSTSGSSSRDSSS 623 Query: 78 STSSSSST 85 STSSSS + Sbjct: 624 STSSSSES 631 Score = 32.7 bits (73), Expect = 1.6 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 9/71 (12%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S+S S + ++TS G SS S S S++ ++S++ TS + +SS Sbjct: 573 SRSRSSSSSSSSSSSTSSSSGSSSSSGS---------SSSRSSSSSSSSTSGSSSRDSSS 623 Query: 63 SSSSSNSSNER 73 S+SSS+ S R Sbjct: 624 STSSSSESRSR 634 Score = 31.6 bits (70), Expect = 3.5 Identities = 21/56 (37%), Positives = 30/56 (53%) Query: 56 KRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASS 111 K + SSSSSSS+SS+ S+SSS S+ S+S ++ S S + SS Sbjct: 572 KSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSS 627 Score = 31.2 bits (69), Expect = 4.6 Identities = 23/64 (35%), Positives = 31/64 (48%) Query: 37 EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 96 E +S T + + K K S SSSSS+SS+ S SSSSS S+S Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610 Query: 97 STSS 100 S++S Sbjct: 611 SSTS 614 Score = 30.4 bits (67), Expect = 7.9 Identities = 43/195 (22%), Positives = 75/195 (38%), Gaps = 29/195 (14%) Query: 14 DEATTSKDGGFSSPSPSAAAAAQ-------EVRSATDGNTSTTPPTSAKKRKLN------ 60 ++ + K+ S P P A Q +++S + + PP+ + L Sbjct: 455 EKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTP 514 Query: 61 SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120 + + ER+DF S + P++P + P + S + S + K Sbjct: 515 QVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKS---KTKTRSRSRGRARNKT- 570 Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAK-- 178 + SSSSSSSSS T+++S S SS +S +G + Sbjct: 571 ----------SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRD 620 Query: 179 SSTTVSSFANSKPGS 193 SS++ SS + S+ S Sbjct: 621 SSSSTSSSSESRSRS 635 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 41.2 bits (95), Expect = 0.004 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%) Query: 336 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380 ++ ++ Q + L +E ERN + +D + + +L LSD LQ Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382 Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436 + + E LEE + + E + L Q+ E + L RL++E D L+ LD Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438 Query: 437 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495 Q+ L++ +EK+ Q+ + LL E + ++S Y R + + + Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486 Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555 +A + E ++T + +D V D+ KN + K A ET + + Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544 Query: 556 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611 + EL + D+KLR N +A + E+ L +D ++ L Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594 Query: 612 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664 ++L ++ D K + AA KLEG KD+EL D I+ ++ Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641 Score = 32.0 bits (71), Expect = 2.7 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%) Query: 355 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411 ER++ E + L+ L S L ++ +++ ET AE ++ +++E+ Sbjct: 866 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921 Query: 412 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469 E LH + RLEEE DR ++ + +E+QL E A QK L + E + Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979 Query: 470 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526 I+ L L+ + + LL++ I S + N +++ + L K+K Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032 Query: 527 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580 + +I ++ K EK + +K E + + A+L A+ + K++ KE Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089 Query: 581 EELEKMLDKI 590 EEL+ L ++ Sbjct: 1090 EELQAALARL 1099 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 41.2 bits (95), Expect = 0.004 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%) Query: 336 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380 ++ ++ Q + L +E ERN + +D + + +L LSD LQ Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389 Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436 + + E LEE + + E + L Q+ E + L RL++E D L+ LD Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445 Query: 437 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495 Q+ L++ +EK+ Q+ + LL E + ++S Y R + + + Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493 Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555 +A + E ++T + +D V D+ KN + K A ET + + Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551 Query: 556 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611 + EL + D+KLR N +A + E+ L +D ++ L Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601 Query: 612 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664 ++L ++ D K + AA KLEG KD+EL D I+ ++ Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648 Score = 32.0 bits (71), Expect = 2.7 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%) Query: 355 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411 ER++ E + L+ L S L ++ +++ ET AE ++ +++E+ Sbjct: 873 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928 Query: 412 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469 E LH + RLEEE DR ++ + +E+QL E A QK L + E + Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986 Query: 470 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526 I+ L L+ + + LL++ I S + N +++ + L K+K Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039 Query: 527 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580 + +I ++ K EK + +K E + + A+L A+ + K++ KE Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096 Query: 581 EELEKMLDKI 590 EEL+ L ++ Sbjct: 1097 EELQAALARL 1106 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 41.2 bits (95), Expect = 0.004 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%) Query: 336 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380 ++ ++ Q + L +E ERN + +D + + +L LSD LQ Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389 Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436 + + E LEE + + E + L Q+ E + L RL++E D L+ LD Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445 Query: 437 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495 Q+ L++ +EK+ Q+ + LL E + ++S Y R + + + Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493 Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555 +A + E ++T + +D V D+ KN + K A ET + + Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551 Query: 556 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611 + EL + D+KLR N +A + E+ L +D ++ L Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601 Query: 612 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664 ++L ++ D K + AA KLEG KD+EL D I+ ++ Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648 Score = 32.0 bits (71), Expect = 2.7 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%) Query: 355 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411 ER++ E + L+ L S L ++ +++ ET AE ++ +++E+ Sbjct: 873 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928 Query: 412 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469 E LH + RLEEE DR ++ + +E+QL E A QK L + E + Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986 Query: 470 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526 I+ L L+ + + LL++ I S + N +++ + L K+K Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039 Query: 527 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580 + +I ++ K EK + +K E + + A+L A+ + K++ KE Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096 Query: 581 EELEKMLDKI 590 EEL+ L ++ Sbjct: 1097 EELQAALARL 1106 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 41.2 bits (95), Expect = 0.004 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%) Query: 336 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380 ++ ++ Q + L +E ERN + +D + + +L LSD LQ Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382 Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436 + + E LEE + + E + L Q+ E + L RL++E D L+ LD Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438 Query: 437 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495 Q+ L++ +EK+ Q+ + LL E + ++S Y R + + + Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486 Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555 +A + E ++T + +D V D+ KN + K A ET + + Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544 Query: 556 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611 + EL + D+KLR N +A + E+ L +D ++ L Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594 Query: 612 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664 ++L ++ D K + AA KLEG KD+EL D I+ ++ Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641 Score = 32.0 bits (71), Expect = 2.7 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%) Query: 355 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411 ER++ E + L+ L S L ++ +++ ET AE ++ +++E+ Sbjct: 866 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921 Query: 412 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469 E LH + RLEEE DR ++ + +E+QL E A QK L + E + Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979 Query: 470 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526 I+ L L+ + + LL++ I S + N +++ + L K+K Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032 Query: 527 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580 + +I ++ K EK + +K E + + A+L A+ + K++ KE Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089 Query: 581 EELEKMLDKI 590 EEL+ L ++ Sbjct: 1090 EELQAALARL 1099 >gi|34452681 ring finger protein 10 [Homo sapiens] Length = 811 Score = 41.2 bits (95), Expect = 0.004 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 M ++SGS N A++ G P ++A A E + +DG S+ +KR+L+ Sbjct: 15 MDKNSGS---NSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSY 71 Query: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF 101 + S N+ + R + + + PP + S+ +SSF Sbjct: 72 PKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSF 111 >gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens] Length = 1013 Score = 41.2 bits (95), Expect = 0.004 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 44 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 103 G + P T+ +SSSSSSS+SS+ S+SSSSS PP P S+ P Sbjct: 72 GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129 Query: 104 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 135 GV AA F D L F+ + A++A Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149 >gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens] Length = 1013 Score = 41.2 bits (95), Expect = 0.004 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 44 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 103 G + P T+ +SSSSSSS+SS+ S+SSSSS PP P S+ P Sbjct: 72 GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129 Query: 104 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 135 GV AA F D L F+ + A++A Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149 >gi|169166609 PREDICTED: similar to ribonucleic acid binding protein S1 isoform 6 [Homo sapiens] Length = 305 Score = 40.4 bits (93), Expect = 0.008 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 12/107 (11%) Query: 3 SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62 S SSGS ++TS G +S S+ +++ S+ G++ST+ +S+ SS Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA-SSRSGSSSTSRSSSS------SS 119 Query: 63 SSSSSNSSNEREDFDSTSSSSSTPPL-----QPRDSASPSTSSFCLG 104 SS S + S R D S S S PP + R S SP + +G Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIG 166 Score = 35.8 bits (81), Expect = 0.19 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Query: 8 SGDGNDDEATTSKDGGFSSPSP--SAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65 S D + ++ KD G SA++ + RS + +S+ TS +SSSS+ Sbjct: 43 SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA 102 Query: 66 SSNSSNEREDFDSTSSSSSTPPLQPR 91 SS S + S+SSSSS P R Sbjct: 103 SSRSGSSSTSRSSSSSSSSGSPSPSR 128 Score = 32.7 bits (73), Expect = 1.6 Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 30/134 (22%) Query: 19 SKDGGFSSPSPSAAAAAQEV----RSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNERE 74 +K +PSP+ + RS G T + + K S+SS SS+ R Sbjct: 18 NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRS 77 Query: 75 DFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKM 134 STSSS S+ +S S++S G S + S Sbjct: 78 RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS----------------------- 114 Query: 135 AEESSSSSSSSSPT 148 SSSSSSS SP+ Sbjct: 115 ---SSSSSSSGSPS 125 Score = 30.8 bits (68), Expect = 6.0 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 14/95 (14%) Query: 10 DGNDDEATT-SKDGGF---SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65 D +D+++ SKD G SS ++ RSA+ G++ST + SSS+ Sbjct: 33 DRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR----------SRSSST 82 Query: 66 SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100 SS+ S+ S SSSSS S S S+SS Sbjct: 83 SSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117 >gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] Length = 737 Score = 40.4 bits (93), Expect = 0.008 Identities = 41/177 (23%), Positives = 75/177 (42%), Gaps = 22/177 (12%) Query: 27 PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS----- 81 P P++ + V S+T + PP S +S+SS SS+ STSS Sbjct: 78 PPPASNEVSTSVLSST---ITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSS 134 Query: 82 -SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSS 140 ++ST ++S +TS+ S++ +S I + T S++ Sbjct: 135 FTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTST-------------STT 181 Query: 141 SSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKL 197 S+SS+S T+ + + S S+ ++ + +ST+ +S + S S +KL Sbjct: 182 STSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKL 238 Score = 35.0 bits (79), Expect = 0.32 Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 18/157 (11%) Query: 44 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRD------SASPS 97 G T PP + +S++ +SNE +S+ + PP+ +++ S Sbjct: 56 GERDTAPPLMLPGPTIATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSS 115 Query: 98 TSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 157 TSS S + SS + T F + +SS+SS ++ TA TS + Sbjct: 116 TSSSSTTSSTSTSSFI----------TSSFT--TSTSITSTSSTSSFTTSTATTSTSISI 163 Query: 158 KNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 194 + S + SS+ S + S++T S+ ++ ++ Sbjct: 164 TSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTS 200 Score = 35.0 bits (79), Expect = 0.32 Identities = 22/102 (21%), Positives = 48/102 (47%) Query: 17 TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDF 76 +TS F++ + + + + +++ ++ T+ TS NS++S+ +++S Sbjct: 143 STSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTS 202 Query: 77 DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 118 STS+SS+ + S ST+S + + P QK+ Sbjct: 203 TSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPHQKQ 244 Score = 33.5 bits (75), Expect = 0.93 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 27/154 (17%) Query: 5 SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST-TPPTSAKKRKLNSSS 63 +S S + +++ F + S + + + S + TST T TS +S S Sbjct: 111 TSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSIS 170 Query: 64 SSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFED 123 SS +++S ST+S+SS S S STS+ S + SS Sbjct: 171 SSITSTST------STTSTSSNSTTSTVTSTSTSTST---STSTSTSS------------ 209 Query: 124 TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 157 F + + ++S+S++S+ T+ATS ++L Sbjct: 210 -----TFTSTTSTSTTSTSTTSTSTSATSSIRKL 238 Score = 33.1 bits (74), Expect = 1.2 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 25 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84 +S S ++ ++ + T +TST+ TS +S++S+S +S STS++SS Sbjct: 176 TSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTS-TSTSATSS 234 Query: 85 TPPLQP-RDSASPSTSSFCLGVSVAASS 111 L P + S+F G+S+ S+ Sbjct: 235 IRKLTPHQKQCGALASAFLFGLSLLVST 262 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.130 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,007,710 Number of Sequences: 37866 Number of extensions: 1339005 Number of successful extensions: 14169 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 127 Number of HSP's successfully gapped in prelim test: 346 Number of HSP's that attempted gapping in prelim test: 9632 Number of HSP's gapped (non-prelim): 2882 length of query: 913 length of database: 18,247,518 effective HSP length: 111 effective length of query: 802 effective length of database: 14,044,392 effective search space: 11263602384 effective search space used: 11263602384 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.