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Search of human proteins with 24415404
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24415404 MDN1, midasin homolog [Homo sapiens]
(5596 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24415404 MDN1, midasin homolog [Homo sapiens] 1.120e+04 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 138 1e-31
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 106 6e-22
gi|217330641 IWS1 homolog [Homo sapiens] 103 6e-21
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 99 9e-20
gi|4504487 histidine rich calcium binding protein precursor [Hom... 98 3e-19
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 96 1e-18
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 91 3e-17
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 91 4e-17
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 91 4e-17
gi|16445033 ACRC protein [Homo sapiens] 85 2e-15
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 84 4e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 83 7e-15
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 83 9e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 82 1e-14
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 80 4e-14
gi|148746195 trichohyalin [Homo sapiens] 80 4e-14
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 79 1e-13
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 79 1e-13
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 79 1e-13
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 79 1e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 1e-13
gi|210032580 SET domain containing 1B [Homo sapiens] 78 2e-13
gi|157738619 smoothelin-like 1 [Homo sapiens] 78 2e-13
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 77 4e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 76 1e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 76 1e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 74 4e-12
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 74 4e-12
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 73 7e-12
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 1.120e+04 bits (29069), Expect = 0.0
Identities = 5596/5596 (100%), Positives = 5596/5596 (100%)
Query: 1 MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVL 60
MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVL
Sbjct: 1 MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVL 60
Query: 61 VGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTS 120
VGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTS
Sbjct: 61 VGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTS 120
Query: 121 PVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHD 180
PVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHD
Sbjct: 121 PVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHD 180
Query: 181 TLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANP 240
TLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANP
Sbjct: 181 TLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANP 240
Query: 241 EVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALR 300
EVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALR
Sbjct: 241 EVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALR 300
Query: 301 SYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLG 360
SYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLG
Sbjct: 301 SYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLG 360
Query: 361 DQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLEN 420
DQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLEN
Sbjct: 361 DQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLEN 420
Query: 421 GELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRE 480
GELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRE
Sbjct: 421 GELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRE 480
Query: 481 LNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTL 540
LNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTL
Sbjct: 481 LNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTL 540
Query: 541 EGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSK 600
EGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSK
Sbjct: 541 EGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSK 600
Query: 601 LNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLI 660
LNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLI
Sbjct: 601 LNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLI 660
Query: 661 EQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVD 720
EQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVD
Sbjct: 661 EQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVD 720
Query: 721 HKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDG 780
HKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDG
Sbjct: 721 HKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDG 780
Query: 781 KDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINL 840
KDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINL
Sbjct: 781 KDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINL 840
Query: 841 AAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRN 900
AAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRN
Sbjct: 841 AAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRN 900
Query: 901 RFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRP 960
RFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRP
Sbjct: 901 RFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRP 960
Query: 961 HYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVK 1020
HYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVK
Sbjct: 961 HYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVK 1020
Query: 1021 SLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPV 1080
SLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPV
Sbjct: 1021 SLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPV 1080
Query: 1081 LIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLID 1140
LIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLID
Sbjct: 1081 LIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLID 1140
Query: 1141 AMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGL 1200
AMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGL
Sbjct: 1141 AMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGL 1200
Query: 1201 YGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSS 1260
YGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSS
Sbjct: 1201 YGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSS 1260
Query: 1261 SVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQ 1320
SVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQ
Sbjct: 1261 SVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQ 1320
Query: 1321 EVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRAL 1380
EVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRAL
Sbjct: 1321 EVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRAL 1380
Query: 1381 EFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKE 1440
EFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKE
Sbjct: 1381 EFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKE 1440
Query: 1441 EIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPE 1500
EIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPE
Sbjct: 1441 EIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPE 1500
Query: 1501 DKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISH 1560
DKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISH
Sbjct: 1501 DKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISH 1560
Query: 1561 NLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAA 1620
NLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAA
Sbjct: 1561 NLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAA 1620
Query: 1621 LKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTE 1680
LKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTE
Sbjct: 1621 LKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTE 1680
Query: 1681 YQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLL 1740
YQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLL
Sbjct: 1681 YQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLL 1740
Query: 1741 RATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKG 1800
RATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKG
Sbjct: 1741 RATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKG 1800
Query: 1801 GEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHE 1860
GEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHE
Sbjct: 1801 GEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHE 1860
Query: 1861 KTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKM 1920
KTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKM
Sbjct: 1861 KTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKM 1920
Query: 1921 VAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGER 1980
VAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGER
Sbjct: 1921 VAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGER 1980
Query: 1981 MRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLL 2040
MRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLL
Sbjct: 1981 MRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLL 2040
Query: 2041 LLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTE 2100
LLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTE
Sbjct: 2041 LLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTE 2100
Query: 2101 LLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLG 2160
LLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLG
Sbjct: 2101 LLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLG 2160
Query: 2161 EGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHG 2220
EGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHG
Sbjct: 2161 EGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHG 2220
Query: 2221 TFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTI 2280
TFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTI
Sbjct: 2221 TFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTI 2280
Query: 2281 TPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSV 2340
TPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSV
Sbjct: 2281 TPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSV 2340
Query: 2341 CDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQH 2400
CDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQH
Sbjct: 2341 CDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQH 2400
Query: 2401 SPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQI 2460
SPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQI
Sbjct: 2401 SPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQI 2460
Query: 2461 LVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAV 2520
LVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAV
Sbjct: 2461 LVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAV 2520
Query: 2521 KLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVF 2580
KLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVF
Sbjct: 2521 KLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVF 2580
Query: 2581 KILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDR 2640
KILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDR
Sbjct: 2581 KILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDR 2640
Query: 2641 EKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLL 2700
EKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLL
Sbjct: 2641 EKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLL 2700
Query: 2701 WVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIP 2760
WVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIP
Sbjct: 2701 WVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIP 2760
Query: 2761 RLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQL 2820
RLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQL
Sbjct: 2761 RLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQL 2820
Query: 2821 KVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLD 2880
KVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLD
Sbjct: 2821 KVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLD 2880
Query: 2881 ELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAML 2940
ELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAML
Sbjct: 2881 ELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAML 2940
Query: 2941 WRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKV 3000
WRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKV
Sbjct: 2941 WRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKV 3000
Query: 3001 SPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGN 3060
SPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGN
Sbjct: 3001 SPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGN 3060
Query: 3061 LNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMA 3120
LNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMA
Sbjct: 3061 LNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMA 3120
Query: 3121 ISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTL 3180
ISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTL
Sbjct: 3121 ISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTL 3180
Query: 3181 GDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQAR 3240
GDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQAR
Sbjct: 3181 GDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQAR 3240
Query: 3241 FDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRM 3300
FDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRM
Sbjct: 3241 FDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRM 3300
Query: 3301 DRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPR 3360
DRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPR
Sbjct: 3301 DRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPR 3360
Query: 3361 SAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHT 3420
SAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHT
Sbjct: 3361 SAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHT 3420
Query: 3421 SLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSG 3480
SLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSG
Sbjct: 3421 SLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSG 3480
Query: 3481 GKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQER 3540
GKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQER
Sbjct: 3481 GKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQER 3540
Query: 3541 IAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGT 3600
IAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGT
Sbjct: 3541 IAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGT 3600
Query: 3601 SDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCY 3660
SDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCY
Sbjct: 3601 SDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCY 3660
Query: 3661 QTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPN 3720
QTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPN
Sbjct: 3661 QTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPN 3720
Query: 3721 VPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEIL 3780
VPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEIL
Sbjct: 3721 VPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEIL 3780
Query: 3781 LAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFS 3840
LAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFS
Sbjct: 3781 LAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFS 3840
Query: 3841 IYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLM 3900
IYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLM
Sbjct: 3841 IYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLM 3900
Query: 3901 PQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIK 3960
PQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIK
Sbjct: 3901 PQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIK 3960
Query: 3961 QSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNR 4020
QSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNR
Sbjct: 3961 QSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNR 4020
Query: 4021 ALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRL 4080
ALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRL
Sbjct: 4021 ALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRL 4080
Query: 4081 VEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLS 4140
VEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLS
Sbjct: 4081 VEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLS 4140
Query: 4141 YRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSL 4200
YRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSL
Sbjct: 4141 YRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSL 4200
Query: 4201 ARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCV 4260
ARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCV
Sbjct: 4201 ARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCV 4260
Query: 4261 QEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGH 4320
QEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGH
Sbjct: 4261 QEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGH 4320
Query: 4321 GNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLW 4380
GNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLW
Sbjct: 4321 GNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLW 4380
Query: 4381 QQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLE 4440
QQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLE
Sbjct: 4381 QQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLE 4440
Query: 4441 SLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGF 4500
SLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGF
Sbjct: 4441 SLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGF 4500
Query: 4501 VEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLED 4560
VEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLED
Sbjct: 4501 VEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLED 4560
Query: 4561 DFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDL 4620
DFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDL
Sbjct: 4561 DFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDL 4620
Query: 4621 VLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGI 4680
VLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGI
Sbjct: 4621 VLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGI 4680
Query: 4681 GEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDG 4740
GEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDG
Sbjct: 4681 GEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDG 4740
Query: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP 4800
ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP
Sbjct: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP 4800
Query: 4801 GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE 4860
GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE
Sbjct: 4801 GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE 4860
Query: 4861 NEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGH 4920
NEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGH
Sbjct: 4861 NEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGH 4920
Query: 4921 EAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQ 4980
EAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQ
Sbjct: 4921 EAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQ 4980
Query: 4981 QSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVEN 5040
QSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVEN
Sbjct: 4981 QSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVEN 5040
Query: 5041 MQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRK 5100
MQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRK
Sbjct: 5041 MQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRK 5100
Query: 5101 PGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDA 5160
PGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDA
Sbjct: 5101 PGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDA 5160
Query: 5161 QTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPL 5220
QTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPL
Sbjct: 5161 QTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPL 5220
Query: 5221 GFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKD 5280
GFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKD
Sbjct: 5221 GFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKD 5280
Query: 5281 VNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQA 5340
VNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQA
Sbjct: 5281 VNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQA 5340
Query: 5341 AKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHT 5400
AKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHT
Sbjct: 5341 AKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHT 5400
Query: 5401 KQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKK 5460
KQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKK
Sbjct: 5401 KQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKK 5460
Query: 5461 TKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNAN 5520
TKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNAN
Sbjct: 5461 TKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNAN 5520
Query: 5521 IFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLS 5580
IFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLS
Sbjct: 5521 IFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLS 5580
Query: 5581 DALRQWFELVTASDHP 5596
DALRQWFELVTASDHP
Sbjct: 5581 DALRQWFELVTASDHP 5596
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 138 bits (348), Expect = 1e-31
Identities = 122/472 (25%), Positives = 212/472 (44%), Gaps = 37/472 (7%)
Query: 4676 EGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDG 4735
E G G G+G + G E ++ +KG EKDK + + +GE E++E +
Sbjct: 648 EDGPEGRGDGTCEEGSS-GAEHWQDEEREKG-EKDKGRGEMERPGEGEK---ELAEKEEW 702
Query: 4736 KMHDGELEEQEEDDE-------KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDE 4788
K DGE +EQ+E ++ + EGG+ + G+ + ++ +E+ +E E E
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762
Query: 4789 EEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDK 4848
E E + +E G EE + K + +++ + + EEKEE +GG+ E+
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 4849 INEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENP 4908
E+ +E + E E + G +E+ E + + G E+ + EGEEE
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEE----------EEGEGKGEEEGEEGEGEEEGE 872
Query: 4909 LEIKEKPEEAGH-EAEERGETETDQNESQSPQEPE---EGPSEDDKAEGEEEMDTG---A 4961
E EE G E EE GE E ++ E + E E EG E+ + +GEEE + G
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 4962 DDQDGDA-AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ 5020
++++G+ + E EE++ E +++E + EG E G +G + + E E E+ + E +
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG-EGEEGEGEGEEEEGEGEGE 991
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNF 5080
E E E G+ E + E G + +G+E G G + + EG E
Sbjct: 992 EEEGEEEGEEEGEGE---EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Query: 5081 IAQLASQKHTRKNTQSFKRK---PGQADNERSMGDHNERVHKRLRTVDTDSH 5129
+ + R+ + + K G+ +NER G+ ++V K +V H
Sbjct: 1049 EGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKH 1100
Score = 135 bits (340), Expect = 1e-30
Identities = 146/630 (23%), Positives = 264/630 (41%), Gaps = 65/630 (10%)
Query: 4611 VPVLSSYSDLVLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGAT 4670
V L +D++ MSL ++ + KL V Q + E +D+A
Sbjct: 490 VESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIG-------ELTQDTALTEND 542
Query: 4671 EFHDYEG-GGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKS---DIKG---E 4723
+ +YE + EG+ K Q Q T + +++ E P+ K D KG E
Sbjct: 543 DSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIE 602
Query: 4724 DNAIEMSEDFDGKMHDGELEEQE-------------EDDEKSDSEGGDLDKHMGDLNGEE 4770
+ +E +E+ + K+H G E+ E E KS E D + GD EE
Sbjct: 603 EQEVEANEE-NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
Query: 4771 ADKLDERLWGDDDEEEDEEEEDN-KTEETGPGMDE--EDSELVAKDDNLDSGNSNKDKSQ 4827
E W D++ E+ E+++ + E G G E E E +D + Q
Sbjct: 662 GSSGAEH-WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQ 720
Query: 4828 QDKKEEKEEAEADDGGQGEDKINEQIDERDYD-----ENEVDPYHGNQEKVPEPEALDLP 4882
+++ +E EE ++ G+GE++ ++ +E + + E E + G +EK
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK---------- 770
Query: 4883 DDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE---TDQNESQSPQ 4939
++ E++ G E+ EEG++ E E+ E G E EE GE E ++ + + +
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEE--EETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Query: 4940 EPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP 4999
E EEG E+++ EGEEE G ++++G+ E E ++ EE + E +EE GE
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEG-EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 5000 ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKE-Q 5058
++G EEEE E EE E E + + G E + E G + E +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947
Query: 5059 GKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVH 5118
G+EE G + + EG + + + + + G+ + E G+ E
Sbjct: 948 GEEEEGEWEGEEEEGEGE-----GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE-EGEE 1001
Query: 5119 KRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSG 5178
+ + + E+ + + +VE + +G + + +E++ +++
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEG-----EGEGEEEEGEEEGEEREKEGEGEENR 1056
Query: 5179 KDQEEEEIEDTLMDTEEQEEFKAADVEQLK 5208
+++EEEE E+ +EE + D E+ K
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQDGEEYK 1086
Score = 133 bits (335), Expect = 4e-30
Identities = 113/453 (24%), Positives = 210/453 (46%), Gaps = 31/453 (6%)
Query: 4666 GEGATEFHDYEGGGIGEGEGMKDVSDQIGNE-EQVEDTFQKGQEKDKEDPDSKSDIKGED 4724
GEG E + E +GE + + G++ E+ ++ + G+E+ E + + D + E+
Sbjct: 690 GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE 749
Query: 4725 NAI-EMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDD 4783
E E+ +G+ +GE E+EE + K + G +K G+ G++ + +E G +
Sbjct: 750 EKEGEGKEEGEGEEVEGE-REKEEGERKKEERAGKEEK--GEEEGDQGEGEEEETEGRGE 806
Query: 4784 EEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGG 4843
E+E+ E + E G G EE+ E ++ G + + ++++ E K E E ++G
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG- 865
Query: 4844 QGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE-E 4902
+GE++ E E + +E E G E+ E E + + + E + GE+ + E +
Sbjct: 866 EGEEEGEEGEGEGEEEEGE-----GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Query: 4903 GEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGAD 4962
GEEE E+ E G E E GE E + E + + EG E+ + EGEEE + +
Sbjct: 921 GEEEG-----EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975
Query: 4963 DQDGDAAQHPEEHSEEQQQSVE--EKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ 5020
+ +G+ + E E+++ E E++ E +EEG G ++ + + E E E+ + E +
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNF 5080
E E E G EN +N + E+E+GK + +G + + +G E
Sbjct: 1036 EEEGEEEGEEREKEGEGEENRRNRE-------EEEEEEGKYQE-TGEEENERQDGEEYKK 1087
Query: 5081 IAQLASQ----KHTRKNTQSFKRKPGQADNERS 5109
++++ KH +S G +RS
Sbjct: 1088 VSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRS 1120
Score = 124 bits (310), Expect = 3e-27
Identities = 110/404 (27%), Positives = 188/404 (46%), Gaps = 24/404 (5%)
Query: 4658 KEFMEDSAGEGATEFHDYEGGGIGEGE-GMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDS 4716
+E E+ GEG E E G E E G + ++ G EE+ E+ +G E ++E+ +
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQG-EGEEEETEG 803
Query: 4717 KSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEG------GDLDKHMGDLNGEE 4770
+ + K E +E E +GK GE EE+EE+ E + EG G+ ++ G+ GEE
Sbjct: 804 RGEEKEEGGEVEGGEVEEGK---GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860
Query: 4771 ADKLDE-RLWGDDDEEEDEEEE-DNKTEETGPGM-DEEDSELVAKDDNLDSGNSNKD--K 4825
+ E G++ E E EEEE + + EE G G +EE+ E +++ G + K
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Query: 4826 SQQDKKEEKEEAEADDG-GQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDD 4884
+++ +E + E E ++G G+GED E +E E E + G E+ E E + +
Sbjct: 921 GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980
Query: 4885 LNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEE---RGETETDQNESQSPQEP 4941
+ + G E+ EEGEEE E +E+ E G E EE GE E ++ E + +E
Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEG--EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038
Query: 4942 --EEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP 4999
EEG + + EGEE ++++ + E ++Q EE K + +G
Sbjct: 1039 GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYG 1098
Query: 5000 ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQN 5043
+ +Q + + + E++ ++ K G +G + N
Sbjct: 1099 KHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSGSKKFWN 1142
Score = 87.8 bits (216), Expect = 3e-16
Identities = 129/629 (20%), Positives = 255/629 (40%), Gaps = 77/629 (12%)
Query: 4687 KDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQE 4746
+++ + + +E+ + + D+ +++ D ++ + D H L E
Sbjct: 453 RNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNE 512
Query: 4747 EDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEED 4806
+ + S + + +G+L + A L +DD +E EE + K G +
Sbjct: 513 KSLKLSPVQKQKKQQTIGELTQDTA------LTENDDSDEYEEMSEMKE---GKACKQHV 563
Query: 4807 SELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVD-P 4865
S+ + + + D+ + + EEKE AE D G G I+E++ + NE +
Sbjct: 564 SQGIFMTQPATTIEAFSDE-EVEIPEEKEGAE-DSKGNG-------IEEQEVEANEENVK 614
Query: 4866 YHGNQEKVPEPEALDLPDDLNL-DSEDKNGGEDTDNEEGEEENPLEI--------KEKPE 4916
HG +++ E + DL D + + + K+ GE D EG + E +++
Sbjct: 615 VHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEER 674
Query: 4917 EAGHEAEERGETETD----------------QNESQSPQEPEEGPSED---DKAEGEEEM 4957
E G + + RGE E E Q +E E+G ++ + EG EE
Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734
Query: 4958 DTGADDQDGDAAQHPEEHSEEQQQSV-EEKDKEADEEGGENGPADQ-GFQPQEEEEREDS 5015
++++GD + E+ E +++ EE + E ++E GE ++ G + + EEE +
Sbjct: 735 HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQG 794
Query: 5016 DTEEQVPEAL-ERKEHASCGQTG--VENMQNTQAMELAGAAPEKE-QGKEEHGSGAADAN 5071
+ EE+ E E KE + G E + E G E+E +G+EE G G +
Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854
Query: 5072 QAEGHESNFIAQLASQ--------KHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRT 5123
+ +G E + + + + + G+ + E G+ E
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 5124 VDTDSHAE--------QGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAK 5175
+ + E +G ++ + + ED + ++G + + + +E+ +
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 5176 DSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVK-- 5233
+ G+ + EEE + + EE EE E+ + EE G E+E E++ +
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEE---EGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031
Query: 5234 ---TEEDQDPRTDKAHKETENEKPERSRE 5259
EE+ + ++ KE E E+ R+RE
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEENRRNRE 1060
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 106 bits (265), Expect = 6e-22
Identities = 130/590 (22%), Positives = 230/590 (38%), Gaps = 84/590 (14%)
Query: 4677 GGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGK 4736
G G+ +G G+ + D +G ++ D D K GE M+++ +GK
Sbjct: 1731 GPGLSQGPGVDEGEDG------------EGSQRLNRDKDPKL---GEAEGDAMAQEREGK 1775
Query: 4737 MHD---------GELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEED 4787
H+ GE E++ E + GG H +L GE A GD D +
Sbjct: 1776 THNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAA------AGGDQDPGQS 1829
Query: 4788 EEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGED 4847
+ E + E E + A + D+ + + + + E EAE + + ED
Sbjct: 1830 DGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESED 1889
Query: 4848 KINEQIDERDYDENE-VDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEE 4906
+ + E+E + +E PE E+++ L++E GED EG E
Sbjct: 1890 VETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA-----LETE----GEDEPESEGAE- 1939
Query: 4907 NPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKA---EGEEEMDTGADD 4963
++ EEA EAE + + E++ ESQ +E + SED +A E E + G
Sbjct: 1940 -----AQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQ 1994
Query: 4964 QDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPE 5023
+ + + PE E Q+ E++ + + +G E P +G + QE E + PE
Sbjct: 1995 PESEDVEAPEAEGEMQE---AEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPE 2051
Query: 5024 ALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQ 5083
+ GVE + + + A ++ +G+ S DA +AEG AQ
Sbjct: 2052 S-----------DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGE-----AQ 2095
Query: 5084 LASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVE 5143
S+ + +K + + G+ +S + P + +AQ E
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGE-----------AQPESEGIEAPEAEGEAQPE 2144
Query: 5144 DADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAAD 5203
+G +++ + E++ + G + E E E E E +A +
Sbjct: 2145 SEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGE----AQPESEGIEAPE 2200
Query: 5204 VEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEK 5253
E E++ G AP +E + E + V+T E + ++ ET+ EK
Sbjct: 2201 AEGEAQPELE-GVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEK 2249
Score = 94.7 bits (234), Expect = 2e-18
Identities = 102/421 (24%), Positives = 173/421 (41%), Gaps = 64/421 (15%)
Query: 4663 DSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKG 4722
+ GEG +E + G G G + ++ + G+++ + +G E P+++ + +
Sbjct: 1791 EQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEA----PEAEGEAQP 1846
Query: 4723 EDNAIEMSE-DFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
E +E E + D + +GE + + ED E ++EG EA E
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG-------------EAQPESE----- 1888
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDS-GNSNKDKSQQDKKEEKEEAEAD 4840
D E E E + + E G E + E + +++++ +D+ + + E +E EA
Sbjct: 1889 -DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAA 1947
Query: 4841 DGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN 4900
+G+ + ++ E E E P + + EAL++ +T
Sbjct: 1948 QEAEGQTQPESEVIESQEAEEEAQP------ESEDVEALEVE-------------VETQE 1988
Query: 4901 EEGEEENPLEIKEKPEEAG--HEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMD 4958
EGE + E E PE G EAEE + E+D E+Q E EE + EGE +
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEA----QEVEGETQKT 2044
Query: 4959 TGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTE 5018
G + D + PE E Q E + E E GE P + QE E ++E
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQ-----EAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESE 2099
Query: 5019 -EQVPEA---LERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAE 5074
+ PEA ++ E +T E ++ +E APE E G+ + S +A AE
Sbjct: 2100 GVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE----APEAE-GEAQPESEGVEAQDAE 2154
Query: 5075 G 5075
G
Sbjct: 2155 G 2155
Score = 82.0 bits (201), Expect = 1e-14
Identities = 94/455 (20%), Positives = 175/455 (38%), Gaps = 36/455 (7%)
Query: 4670 TEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEM 4729
TE D E + ++ + + + Q E + QE ++E D++ + +E
Sbjct: 1927 TEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVET 1986
Query: 4730 SEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE---EADKLDERLWGDDDEEE 4786
E +GE + + ED E ++EG M + E E+D ++ + + +E +
Sbjct: 1987 QEA------EGEAQPESEDVEAPEAEG-----EMQEAEEEAQPESDGVEAQPKSEGEEAQ 2035
Query: 4787 DEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGE 4846
+ E E KTE G + +S+ V + + + + Q+ + E E+E D + E
Sbjct: 2036 EVEGETQKTE----GDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 4847 DKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEE 4906
+ + + + E E + + PE E P+ +++ + G E EG E
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEG-EAQPESEGVEA 2150
Query: 4907 NPLEIKEKPEEAGHEAEERGETETDQNES-QSPQEPEEGPSEDDKAEGEEEMDTGADDQD 4965
E + +PE G EA+E E + E ++P+ E E + E E + +
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELE 2210
Query: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL 5025
G A EE ++ + + VE + E GE P +G E + + QV
Sbjct: 2211 GVEAPEAEEEAQPEPEGVETPEAE-----GEAQPESEG------ETQGEKKGSPQVSLGD 2259
Query: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADAN-----QAEGHESNF 5080
+ E AS + V + T G P + G + S + ++ Q + +
Sbjct: 2260 GQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHV 2319
Query: 5081 IAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNE 5115
+ S T +RK + E S + E
Sbjct: 2320 LGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEE 2354
Score = 76.6 bits (187), Expect = 6e-13
Identities = 103/460 (22%), Positives = 181/460 (39%), Gaps = 63/460 (13%)
Query: 4885 LNLDSEDKNGGEDTDNEEGEEENPLEIKEKP--EEAGHEAEERGETETDQNESQSPQEPE 4942
LN D + K G + D E E E E G EAE+ GE +++ E+
Sbjct: 1752 LNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELG-EAEQEGEGISERGETGGQGSGH 1810
Query: 4943 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE--EKDKEADEEGGENGPA 5000
E + + A G ++ +D +G A E ++ + + VE E + +A E GE P
Sbjct: 1811 EDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPE 1870
Query: 5001 DQGFQPQEEE-----EREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPE 5055
+ + E E E ED +T E E E A + E T+++E
Sbjct: 1871 SEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEAL----- 1925
Query: 5056 KEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNE 5115
+ +G++E S A+A +AE Q + ++ ++ + ++++ ++
Sbjct: 1926 ETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEAL----- 1980
Query: 5116 RVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQ---Q 5172
V + + ++ E + P+A+ E +A E + SD +AQ + Q+ +
Sbjct: 1981 EVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGE 2040
Query: 5173 SAKDSG-------------KDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAP 5219
+ K G ++E +E E + + E + ++ DV+ + E G P
Sbjct: 2041 TQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE----GEAQP 2096
Query: 5220 --LGFDEMEVEIQTVKTEEDQDPRTD-KAHKETEN-EKPERSRESTIHTAHQFLMDTIFQ 5275
G + E E + K E + P T+ +A E+E E PE E+ Q
Sbjct: 2097 ESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEA--------------Q 2142
Query: 5276 PFLKDVNELRQELERQ-----LEMWQPRESGNPEEEKVAA 5310
P + V E E Q +E + E PE E V A
Sbjct: 2143 PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEA 2182
Score = 74.3 bits (181), Expect = 3e-12
Identities = 93/386 (24%), Positives = 156/386 (40%), Gaps = 48/386 (12%)
Query: 4912 KEKPEEAGHEAEE--RGETETDQNESQSPQEPE--------EGPSEDDKAEGE------E 4955
+++ E EA E G+T TD +++ Q E +GP D+ +GE
Sbjct: 1695 RKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNR 1754
Query: 4956 EMDTGADDQDGDA-AQHPEEHSEEQQQSVEEKDKEADEEG------GENGPADQGFQPQ- 5007
+ D + +GDA AQ E + + S + EA++EG GE G G +
Sbjct: 1755 DKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNL 1814
Query: 5008 -------EEEEREDSDTEEQVPEALERKEHASCGQTGVENMQ-NTQAMELAG-AAPEKE- 5057
+++ SD E + EA E + A GVE + A E G A PE E
Sbjct: 1815 QGEAAAGGDQDPGQSDGAEGI-EAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESED 1873
Query: 5058 -QGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNER 5116
+ E G ++ E E+ + Q S+ + + ++ +E
Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933
Query: 5117 VHKRLRTVDTDSHAEQGPAQ-QPQAQV-EDADAFEHIKQGSDAYDAQTYDVASKEQQQSA 5174
+ + + A++ Q QP+++V E +A E + S+ +A +V ++E + A
Sbjct: 1934 ESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA 1993
Query: 5175 KDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKT 5234
+ +D E E E + + EE+ + ++ VE E G + EVE +T KT
Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSE---------GEEAQEVEGETQKT 2044
Query: 5235 EEDQDPRTDKAH-KETENEKPERSRE 5259
E D P +D E E E E E
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGE 2070
Score = 52.4 bits (124), Expect = 1e-05
Identities = 72/293 (24%), Positives = 119/293 (40%), Gaps = 54/293 (18%)
Query: 4821 SNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALD 4880
+N+D++++D +E++ + + E+ + E++ + E G + + + EA+
Sbjct: 1271 TNEDEAERDSEEQRASSNLEQ--LAENTVQEEVQLEETKE-------GTEGEGLQEEAVQ 1321
Query: 4881 LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGH-------EAEERGET--ETD 4931
L E+T EEG +E ++++E E G + EE ET E
Sbjct: 1322 L--------------EETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGL 1367
Query: 4932 QNESQSPQEPEEGPSEDDKAEGEEE--MDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKE 4989
Q E +E +EGP + E EE + G ++ Q E S + +E D
Sbjct: 1368 QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPV 1427
Query: 4990 ADEEGG------ENGPADQGFQPQEE----EEREDSDTEEQVPEALERKEHASCGQTGVE 5039
+EE G E PA+ +P E E + S +E Q LE G T +
Sbjct: 1428 QEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGAT-MM 1486
Query: 5040 NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQ------AEGHESNFIAQLAS 5086
++TQA GAA E+ S A D + + E F+A LAS
Sbjct: 1487 GQEHTQAQPTQGAA---ERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLAS 1536
Score = 42.4 bits (98), Expect = 0.013
Identities = 53/251 (21%), Positives = 98/251 (39%), Gaps = 48/251 (19%)
Query: 4708 EKDKEDPDSKSDIKG-----EDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKH 4762
E+D E+ + S+++ +++ E +G +G EE + +E EG
Sbjct: 1277 ERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ---- 1332
Query: 4763 MGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEET-GPGMDEEDSELVAKDDNLDSGNS 4821
EE +L+E + + +++EE + + EET G G+ EE +L + + G
Sbjct: 1333 ------EEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 4822 NKDKSQQDKKE-----------EKEEAEADD--GGQGEDKINEQIDERDYDENEVDPYHG 4868
+ + K+E E EA + D G Q +D + E+ R E P G
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG 1446
Query: 4869 NQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK---EKPEEAGHEAEER 4925
+E P L +TD E ++ +++ EKP A +E
Sbjct: 1447 TEEPTEPPSHL----------------SETDPSASERQSGSQLEPGLEKPPGATMMGQEH 1490
Query: 4926 GETETDQNESQ 4936
+ + Q ++
Sbjct: 1491 TQAQPTQGAAE 1501
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 103 bits (256), Expect = 6e-21
Identities = 131/549 (23%), Positives = 217/549 (39%), Gaps = 89/549 (16%)
Query: 4653 GFCLPKEFMEDSAGEGATEFHDYEGG---GIGEGEGMKDVSDQIGNEEQVEDTFQKGQEK 4709
G P + DS +G + ++ G G E + SD+ ED KG
Sbjct: 14 GGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDR-------EDGLPKGHHV 66
Query: 4710 DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
+ D ++ D+ E E K D E EE+ E SDSE D+++H D E
Sbjct: 67 TDSENDEPLNLNASDS--ESEELHRQKDSDSESEERAEPPA-SDSENEDVNQHGSDSESE 123
Query: 4770 EADKL-------DERLWG--DDDEEED---------EEEE-------DNKTEET-GPGMD 4803
E KL +E L G D E ED E EE D++TE+ P +
Sbjct: 124 ETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQIS 183
Query: 4804 EEDSELVAKDDNLDSGNSNKDKSQQDKKEEKE---------EAEADDGGQGEDKINEQID 4854
+ +SE + DS N K + E +E E+E Q D NE++
Sbjct: 184 DSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELP 243
Query: 4855 ERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSED--KNGGEDTDNEEGEEENPLEIK 4912
+ ++E + +Q E E L P + +SED +N D++NEE + + +
Sbjct: 244 KPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSE 303
Query: 4913 EKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHP 4972
+ + G ++ ETE Q P+ ++ E+ + E + D+ D D +
Sbjct: 304 SEGPQKGPASDS--ETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFH 361
Query: 4973 EEHSEEQQQSVEEKDKEADEEGGENGPADQG----FQPQEEEEREDSDTEEQVPEALERK 5028
SEE++ ++ D + DE+ GE + E+EE+ + V +A +
Sbjct: 362 SSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSD 421
Query: 5029 EHASCGQTGV-ENMQNTQAMELAG--AAPEKEQGKEEHGSGAADANQAEGHESNFIAQLA 5085
A ++G E + + E AG + +K + K+ GS + N+ E N IA +
Sbjct: 422 SDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNE----EENLIADIF 477
Query: 5086 SQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDA 5145
+ G + E G + E D E+G Q +A ED+
Sbjct: 478 GES-------------GDEEEEEFTGFNQE-----------DLEEEKGETQVKEA--EDS 511
Query: 5146 DAFEHIKQG 5154
D+ ++IK+G
Sbjct: 512 DSDDNIKRG 520
Score = 82.4 bits (202), Expect = 1e-14
Identities = 103/502 (20%), Positives = 201/502 (40%), Gaps = 69/502 (13%)
Query: 4800 PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDG---------GQGEDKIN 4850
P DE DS +DD ++ +S D ++ E E ++ +DG + ++ +N
Sbjct: 18 PVQDERDSGSDGEDD-VNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLN 76
Query: 4851 EQIDERDYDE--NEVDPYHGNQEKVPEPEALDLPDDLNLDSED-------KNGGEDTDNE 4901
+ + +E + D ++E+ P + +D+N D K G D++NE
Sbjct: 77 LNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENE 136
Query: 4902 E------GEEEN-----------PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEG 4944
E + EN +E +K + E E+ + + +ES+ P +
Sbjct: 137 ELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQAS 196
Query: 4945 PSEDDKAEGEEEMDTGADD------QDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENG 4998
SE+++ D+ +++ D ++ + P + + + K + +D E E+
Sbjct: 197 DSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSE-SEDP 255
Query: 4999 PADQGFQPQEEE---------ERED------SDTE-EQVPEALERKEHASCGQTGVENMQ 5042
P Q + EE E ED SD+E E++P+ + Q G +
Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDS 315
Query: 5043 NTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPG 5102
T+ PE + + G Q + S+ + + K++
Sbjct: 316 ETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKM 375
Query: 5103 QADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQT 5162
+D + G+ E+V KR V +DS E+ + + V DAD + SD +
Sbjct: 376 DSDEDEKEGE-EEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDS-DAVSDKSGKRE 433
Query: 5163 YDVASKEQQQSAKD-SGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLG 5221
+AS ++++ K+ S K EE+++ + ++ +EE AD+ +E + T G
Sbjct: 434 KTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFT---G 490
Query: 5222 FDEMEVEIQ----TVKTEEDQD 5239
F++ ++E + VK ED D
Sbjct: 491 FNQEDLEEEKGETQVKEAEDSD 512
Score = 67.0 bits (162), Expect = 5e-10
Identities = 114/524 (21%), Positives = 196/524 (37%), Gaps = 78/524 (14%)
Query: 4813 DDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEK 4872
D SG+ + D ++E+ D G GED +NEQ D G+ E+
Sbjct: 2 DSEYYSGDQSDDGGATPVQDER-----DSGSDGEDDVNEQHSGSDT---------GSVER 47
Query: 4873 VPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE------EENPLEIKEKPEEAGHEAEERG 4926
E E D D L G TD+E E ++ E + +++ E+EER
Sbjct: 48 HSENETSDREDGL------PKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERA 101
Query: 4927 ETETDQNESQSP-QEPEEGPSEDDK------AEGEEEMDTGADDQDG-DAAQHPEEHSE- 4977
E +E++ Q + SE+ + +E EE ++ A D + D +HP SE
Sbjct: 102 EPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEI 161
Query: 4978 EQQQSVEEKDKEADE--------EGGENGPADQGFQPQEEE----EREDSDTEEQVPEAL 5025
E+ Q D E ++ E P Q + EE DS++EE +
Sbjct: 162 EELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQV 221
Query: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLA 5085
E + + +N + + + E E S + + + S+ ++
Sbjct: 222 SDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDP 281
Query: 5086 SQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDA 5145
+ + KP +D+E S G S +E A + + + E
Sbjct: 282 PRNQASDSENEELPKPRVSDSE-SEGPQK----------GPASDSETEDASRHKQKPESD 330
Query: 5146 DAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVE 5205
D + +G D + Q S K D EEEE + MD++E E +
Sbjct: 331 DDSDRENKGEDT-EMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDE-------K 382
Query: 5206 QLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTA 5265
+ + E++ A L E E + K+ D D + + ++K + RE TI +
Sbjct: 383 EGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSD--ADDSDSDAVSDKSGK-REKTIASD 439
Query: 5266 HQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVA 5309
+ + K++++ + E E+ L ESGN EE +A
Sbjct: 440 SE-------EEAGKELSDKKNE-EKDL-FGSDSESGNEEENLIA 474
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 99.4 bits (246), Expect = 9e-20
Identities = 125/583 (21%), Positives = 242/583 (41%), Gaps = 87/583 (14%)
Query: 4682 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 4741
E E + V+DQ+ Q +++ + + + ++G+D A +
Sbjct: 55 EEESLGQVTDQVEVNAQ-----NSVPDEEAKTTTTNTQVEGDDEAAFLER---------- 99
Query: 4742 LEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPG 4801
L +EE +K E + K + + L R +D E + E++ K+E
Sbjct: 100 LARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQER 159
Query: 4802 MDEEDSELVAKDDNLDSGNSNKDKSQQDK-KEEKEEAEADDGGQGEDKINEQIDERDYDE 4860
+ E++E V K + ++ ++DK KEE+EE + G GE+++ ++E+ +
Sbjct: 160 YEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTES 219
Query: 4861 NE---VDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEE 4917
E V Q EP+ + E + G ++ + E EE E + + E
Sbjct: 220 QEETVVMSLKNGQISSEEPKQ---------EEEREQGSDEISHHEKMEEEDKE-RAEAER 269
Query: 4918 AGHEAEERGETETDQN-------------ESQSPQEPEEGPSEDDKAEGEEEMDTGADDQ 4964
A EAEER + +Q+ E + QE E +E+ + EEE + Q
Sbjct: 270 ARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQ 329
Query: 4965 DGDAAQHPEEHSEEQQQSVEEKDKEADEEGG-----ENGPADQGFQPQEEEEREDSDTEE 5019
+ E+ + E++Q ++E++K A EE E A++ + + EEE + E+
Sbjct: 330 ---RIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 5020 QVPEALERKEHASCGQTGVENMQNTQAME------------LAGAAPEKEQGKEEHGSGA 5067
+ + LE K+HA +T ++ + Q +E A K+QG+E+
Sbjct: 387 KRNKQLEEKKHAM-QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQ 445
Query: 5068 ADANQAEGHESNFIAQ------LASQKHTRKNTQSFK-RKPGQADNERSMGD-------H 5113
A + + + F + + K ++ +SF RK G + + G+ H
Sbjct: 446 AKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 505
Query: 5114 NERVHKR---LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQ 5170
E R +VDT AE P QVE E +++ +++ ++ ++Q
Sbjct: 506 TENTFSRPGGRASVDT-KEAEGAP------QVEAGKRLEELRRRRGETESEEFEKLKQKQ 558
Query: 5171 QQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIK 5213
Q++A + + +++ E +++ EEQ + +L+ EE K
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK 601
Score = 69.7 bits (169), Expect = 8e-11
Identities = 112/546 (20%), Positives = 214/546 (39%), Gaps = 117/546 (21%)
Query: 4678 GGIGEG--EGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDG 4735
G IGE E M + EE V + + GQ +E + +G D E+S
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSD---EIS----- 252
Query: 4736 KMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADK--LDERLWGDDDEEEDEEEEDN 4793
H ++E EED E++++E L+ + E DK DER + +E+ +E +
Sbjct: 253 --HHEKME--EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 4794 KTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQI 4853
+ E M EE+ ++ Q+ K+EEK AE
Sbjct: 309 REAEERERMREEEKRAA-------------EERQRIKEEEKRAAE--------------- 340
Query: 4854 DERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKE 4913
++++ E E + + E+K E+ EEE +++E
Sbjct: 341 ---------------ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE 385
Query: 4914 KPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPE 4973
+ E ++ ET + + + ++ EG ++K E+++ T + G
Sbjct: 386 QKRNKQLEEKKHAMQET-KIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQG------- 437
Query: 4974 EHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASC 5033
EE+ V+ K ++ E+ P + + ++E+ ++D + +E+V ++RK+
Sbjct: 438 ---EEKGTKVQAKREKLQED----KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKK---- 486
Query: 5034 GQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKN 5093
G T V++ QN + M E + G + D +AEG A Q K
Sbjct: 487 GFTEVKS-QNGEFMTHKLKHTENTFSR-PGGRASVDTKEAEG---------APQVEAGKR 535
Query: 5094 TQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQ 5153
+ +R+ G+ ++E ++L+ Q Q E A E +K+
Sbjct: 536 LEELRRRRGETESEE---------FEKLK----------------QKQQEAALELEELKK 570
Query: 5154 GSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIK 5213
+ + + +EQ++ +++ + EEE + L + E+ +AA+ Q PE+
Sbjct: 571 ---KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 627
Query: 5214 SGTTAP 5219
S P
Sbjct: 628 SDDKKP 633
Score = 66.2 bits (160), Expect = 8e-10
Identities = 92/513 (17%), Positives = 201/513 (39%), Gaps = 39/513 (7%)
Query: 4731 EDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADK------LDERLWGDDDE 4784
+DF+ + EL Q+ ++ + ++E + D + EEA + ERL +E
Sbjct: 2 DDFERRR---ELRRQKREEMRLEAER--IAYQRNDDDEEEAARERRRRARQERLRQKQEE 56
Query: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ 4844
E + D + +E+++ + ++ + + ++EE+ + + +
Sbjct: 57 ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALE 116
Query: 4845 GEDKINEQIDE-----------RDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKN 4893
+ + + I + D ENE E E ++ + + S KN
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVT-KSYQKN 175
Query: 4894 GGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEG 4953
D + + E++ E +E+ + G E + E ++ ++S +E ++ +
Sbjct: 176 DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS 235
Query: 4954 EEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE 5013
EE +Q D H E+ EE ++ E + + E E A+Q + +E R
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295
Query: 5014 DSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQA 5073
+++ E+ + ER+E E + + E AA E+++ KEE A + +
Sbjct: 296 EAE-EKAAAQERERRE--------AEERERMREEE-KRAAEERQRIKEEEKRAAEERQRI 345
Query: 5074 EGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQG 5133
+ E + K K +++ + E++ + KR + ++ HA Q
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE----QKRNKQLEEKKHAMQE 401
Query: 5134 PAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDT 5193
+ + + + ++ + QT + + +++ K K ++ +E + T
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461
Query: 5194 EEQEEFKAADVEQLKPEEIKSGTTAPLGFDEME 5226
E ++E D E EE+KS GF E++
Sbjct: 462 EIKDEKIKKDKE--PKEEVKSFMDRKKGFTEVK 492
Score = 54.7 bits (130), Expect = 3e-06
Identities = 78/409 (19%), Positives = 148/409 (36%), Gaps = 46/409 (11%)
Query: 4912 KEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQH 4971
++K EE EAE D +E ++ +E ++ + +EE G +
Sbjct: 12 RQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ 71
Query: 4972 PEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHA 5031
EE + + E D+E E R + ++++ EALER++
Sbjct: 72 NSVPDEEAKTTTTNTQVEGDDEAAF----------LERLARREERRQKRLQEALERQKEF 121
Query: 5032 SCGQTGVE------NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLA 5085
T MQN A EK + ++E + ++ N
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKN---DWR 178
Query: 5086 SQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDA 5145
+ +K + + + + S+G++ V +T ++ + Q E+
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 5146 DAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVE 5205
E +QGSD +++ E+ + +D+E E E ++ EE+E KA +
Sbjct: 239 KQEEEREQGSD-------EISHHEKMEE-----EDKERAEAERARLEAEERERIKAEQDK 286
Query: 5206 QLKPEEIKSGTTAPLGFDEME----VEIQTVKTEEDQDPRTDKAHKETEN---EKPERSR 5258
++ E + E E E + ++ EE + + KE E E+ +R +
Sbjct: 287 KIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIK 346
Query: 5259 ESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEK 5307
E A + + +K+ E R ERQ + E EE+K
Sbjct: 347 EEEKRAAEE-------RQRIKE-EEKRAAEERQRARAEEEEKAKVEEQK 387
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 97.8 bits (242), Expect = 3e-19
Identities = 114/465 (24%), Positives = 182/465 (39%), Gaps = 91/465 (19%)
Query: 4658 KEFMEDSAGEGATEF----HDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKED 4713
+E E+ E +TE+ H + G G E E DVSD G+ +G E+D +D
Sbjct: 195 EEEEEEEEEEASTEYGHQAHRHRGHGSEEDE---DVSD--GHHHHGPSHRHQGHEEDDDD 249
Query: 4714 PDSKSDIKGEDNA---------------IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGD 4758
D D +D+ IE ED H + + E+ D++ D
Sbjct: 250 DDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDD 309
Query: 4759 LDKHMG-------DLNGEEADKL---------DERLWGDDDEEEDEEEEDNKTEETGPGM 4802
+ G D EE + + D R G DEEEDE D TE G
Sbjct: 310 VSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDE---DVSTERWHQGP 366
Query: 4803 DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ--GEDKINEQIDERDY-D 4859
LV D++EE+EE G + DE D+ D
Sbjct: 367 QHVHHGLV------------------DEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQD 408
Query: 4860 ENEVDPYHGNQEKVPEPEALDLPDDLNLDSED-KNGGEDTDNEEGEEENPLEIKEKPEEA 4918
E + + H + +VP E ++ +L + + +D + G+ + E+ P
Sbjct: 409 EYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPP-- 466
Query: 4919 GHEA-EERGETETDQNESQSPQEPEEGPSEDD---KAEGEEEMDTGADDQD--------- 4965
GH ++R D +E + +E + G E+D +GE+ G+ DQ+
Sbjct: 467 GHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGH 526
Query: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENG-PADQGFQPQEEEEREDSDTEEQ---- 5020
G + EE E++++ EE+D+E EE E G P +EEEE E + +E
Sbjct: 527 GLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTI 586
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGS 5065
+P L+R+E A + E+ ++T G +E G + GS
Sbjct: 587 IPNPLDRREEAGGASSEEESGEDT------GPQDAQEYGNYQPGS 625
Score = 90.5 bits (223), Expect = 4e-17
Identities = 114/521 (21%), Positives = 203/521 (38%), Gaps = 68/521 (13%)
Query: 4783 DEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDG 4842
DE +D E+ + P ++ED ++ + +L G+ ++D D+ EE A+ G
Sbjct: 69 DENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHG 128
Query: 4843 GQ-------GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNG- 4894
GQ G + + + R + + H +++ E E + ++ G
Sbjct: 129 GQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDED---EDEVVSSEHHHHILRHGHRGH 185
Query: 4895 -GEDTDNEEGEEENPLEIKEKPEEAGHEA-------EERGETETDQNESQSPQEPEEGPS 4946
GED + EE EEE E +E E GH+A E E +D + P +G
Sbjct: 186 DGEDDEGEEEEEEEEEE-EEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHE 244
Query: 4947 EDDKAEGEEEMDTGADD------------------QDGDAAQ-HPEEHSEEQQQSVEEKD 4987
EDD + +++ D DD +D D + H + +S EE D
Sbjct: 245 EDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDD 304
Query: 4988 KEADEEGGENGPADQGFQPQEEEERE--DSDTEEQVPEALER--KEHASCGQTGVENMQN 5043
+ D+ E G Q +EE E + VP+ + ++ E
Sbjct: 305 NDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQ 364
Query: 5044 TQAMELAGAAPEKEQGKE---EHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRK 5100
G E+E+ +E + G A ++Q GH+S+ + T R
Sbjct: 365 GPQHVHHGLVDEEEEEEEITVQFGHYVA-SHQPRGHKSD-EEDFQDEYKTEVPHHHHHRV 422
Query: 5101 PGQADNERSMG-DHNERVHKRLRTVDTDSHAEQGPAQQ------------PQAQVEDADA 5147
P + D E S H H++ + H ++G ++ ++ + D+
Sbjct: 423 PREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDS 482
Query: 5148 FEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIED-----TLMDTEEQEEFKAA 5202
E ++ D + D +S++ ++ +DQE+EE E+ +L EE+EE K
Sbjct: 483 EEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEE 542
Query: 5203 DVEQLKPE--EIKSGTTAPLGFDEMEVEIQTVKTEEDQDPR 5241
+ E+ E E ++ APL D E E + + E+ +PR
Sbjct: 543 EEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPR 583
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 95.9 bits (237), Expect = 1e-18
Identities = 121/594 (20%), Positives = 256/594 (43%), Gaps = 47/594 (7%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSE 4755
EE++ + Q+G+ +++E+ + + + + E+ E EL EQEE ++ + +
Sbjct: 299 EERLRE--QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 4756 GGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDN 4815
+ ++ M + E+ + +ERLW ++E+ E++ K + M E+D L K++
Sbjct: 357 MWEQEEKMREQE-EKMWRQEERLW---EQEKQMREQEQKMRDQEERMWEQDERLREKEER 412
Query: 4816 LDSGNS---NKDKSQQDKK---EEKEEAEADDGGQGEDKINEQI----DERDYDENEVDP 4865
+ +K +++KK +EK+ + ++ Q E++I E+ +E + + +
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEE--ENPLEIKEKPEEAGHEAE 4923
+E + E E + + ++K ++ E+ E+ E +I+++ E G E +
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532
Query: 4924 E-RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQS 4982
R E +Q + QE + E + EE M+ +Q+ E+ EE++
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER-- 590
Query: 4983 VEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENM- 5041
+ E++K+ EE ++ Q QEE+ +E + + E ++ +E Q E M
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE--EKMW 648
Query: 5042 QNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP 5101
+ + M PE+++ EH E E ++ Q+ K TQ ++K
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE-----KIWEQEKMEKKTQEQEKKT 703
Query: 5102 GQADNERSMGDHNERVHKRLRTVDT--DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYD 5159
+ R ER K++R + E+ Q+ + Q ++ + +E ++ + +
Sbjct: 704 WDQEKMREEESMRER-EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 5160 AQTYDVASKEQQQSAKDSGKDQEEEEI---EDTLMDTEE----QEEFKAADVEQLKPEEI 5212
EQ++ + K QE+E+I E+ + D EE QEE E+++ +E
Sbjct: 763 KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Query: 5213 KS--------GTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSR 5258
K G + E ++ Q K EE + +K ++ E + + +
Sbjct: 823 KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEK 876
Score = 87.0 bits (214), Expect = 5e-16
Identities = 110/554 (19%), Positives = 227/554 (40%), Gaps = 62/554 (11%)
Query: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQD 4829
+ + L E +W ++E ++E++ K EE +E E K + ++K ++
Sbjct: 266 QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE 325
Query: 4830 KKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDS 4889
+++E E E + Q E + EQ ++ E ++ +EK+ E E + L
Sbjct: 326 QEKELREQEKELREQKE--LREQEEQMQEQEEKM---WEQEEKMREQEEKMWRQEERLWE 380
Query: 4890 EDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDD 4949
++K E +EE E +E E EER +E E+ + +
Sbjct: 381 QEKQMREQEQKMRDQEERMWE----QDERLREKEER------------MREQEKMWEQVE 424
Query: 4950 KAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEE 5009
K E++M Q+ + +E ++++ + E++K+ EE ++ Q QEE
Sbjct: 425 KMREEKKM------QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 5010 EEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAAD 5069
E + E Q E+KE E MQ E+E+ E D
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKL----WEQEKMQ------------EQEEKIWEQEEKIRD 522
Query: 5070 ANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSH 5129
+ G E Q +K + Q ++++ D E+ M D ER+ K+ + + +
Sbjct: 523 QEEMWGQEKKMWRQ---EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 5130 AEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDT 5189
++ ++ + E ++ + + + K Q+Q K ++++ +E E+
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 5190 LMDTEE---QEEFKAADVEQLKPEEIKSGTTAPLGFDE-MEVEIQTVKTEEDQDPRTDKA 5245
+ + EE ++E K + ++L ++ K + E M+ + + + +E + +T +
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 5246 HKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQL-----EMWQPRES 5300
K+T +++ R ES + + + +++ E QE E ++ EMW+ E
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREE---EEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 5301 GNPEEEKVAAEMWQ 5314
+EEK MW+
Sbjct: 757 MWEQEEK----MWE 766
Score = 73.9 bits (180), Expect = 4e-12
Identities = 97/538 (18%), Positives = 211/538 (39%), Gaps = 46/538 (8%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
E E + D E + E +++ +++ +E++ + +K +E+ K K K
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK---K 438
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
D +M E+ ++ + E + +EE++ + E E+ K +E +W
Sbjct: 439 TRDQEEKMQEE--ERIREREKKMREEEETMREQE-------------EKMQKQEENMWEQ 483
Query: 4782 DDEEEDEEEEDNKTEETGPG--MDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA 4839
+++E ++ + E+ M E++ ++ +++ + + ++ ++EK +
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 4840 DDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTD 4899
D + E+K+ +Q + E ++ QEK + + ++ + +K E+ +
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 4900 NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
+EE E +EK +E + E+ E +Q E QE + E+ E + +
Sbjct: 604 MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 4960 GADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
+ + Q E+ E++++ E++ E + E DQ +EE RE
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 5020 QVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESN 5079
+ E + +E E MQ + EK Q +EE + E E
Sbjct: 724 EEEEMMREQE---------EKMQEQE---------EKMQEQEEE-MWEQEEKMWEQEEKM 764
Query: 5080 FIAQ-LASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQP 5138
+ Q L QK + + + + E M D E++ + + +G ++
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Query: 5139 QAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ 5196
Q E E G Q + +E++ K G++++ E E+ + EE+
Sbjct: 825 WGQEEKMWGQEEKMWG------QEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEK 876
Score = 63.2 bits (152), Expect = 7e-09
Identities = 64/315 (20%), Positives = 148/315 (46%), Gaps = 20/315 (6%)
Query: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEE 4747
D +++ EE++ + +K +E+++ + + ++ ++ ++ E+ KM + E + QE+
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE---KMWEQEEKMQEQ 636
Query: 4748 DDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDS 4807
+++ + E ++ + + E+LW E E +E++ E+ ++E
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW----EHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 4808 ELVAKDDNLDSGNSNKDKSQQD--KKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDP 4865
E ++ + + K + ++ ++E+K E + + E+K+ EQ ++ E E+
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM-- 750
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEA---GHEA 4922
+EK+ E E + + L + + E +E E+ E K + +E G E
Sbjct: 751 -WEQEEKMWEQEE-KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE 808
Query: 4923 EERGETETDQNESQSPQEPEEGP-SEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQ 4981
+ RG+ E + + + EE +++K G+EE G +++ + Q EE EQ++
Sbjct: 809 KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868
Query: 4982 SV---EEKDKEADEE 4993
+ EEK +E +E+
Sbjct: 869 KMRGQEEKMREQEEK 883
Score = 47.8 bits (112), Expect = 3e-04
Identities = 87/461 (18%), Positives = 172/461 (37%), Gaps = 72/461 (15%)
Query: 4972 PEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHA 5031
P+ + Q+ + +++E E+ + ++ QEE RE + E + R+E
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 5032 SCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTR 5091
Q Q + E ++EQ +E+ + E Q ++
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ--EERLWE 380
Query: 5092 KNTQSFKRKPGQADNERSMGDHNERV-----------------------------HKRLR 5122
+ Q +++ D E M + +ER+ K+ R
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 5123 TVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQ- 5181
+ E+ ++ + E+ + ++ + ++ KE QQ K++
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 5182 -EEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEE---- 5236
E+E++++ EQEE K D E++ +E K + E ++ Q K +
Sbjct: 501 WEQEKMQEQEEKIWEQEE-KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 559
Query: 5237 --DQDPRTDKAHKETEN---EKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQ 5291
DQ+ R +K +E E ++ E+ RE + M + +++ E QE E +
Sbjct: 560 MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE-EEEMMREQEEKMQEQEEK 618
Query: 5292 LE-----MWQPRESGNPEEEKV---AAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKL 5343
++ MW+ E +EEK+ +MW+ +++ E+ RL P Q KL
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ--------EEKMWEQQRL---PEQKEKL 667
Query: 5344 KGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQ 5384
+ K K+ Q +++KIW + K Q Q
Sbjct: 668 ---WEHEKMQEQEKM------QEQEEKIWEQEKMEKKTQEQ 699
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 90.9 bits (224), Expect = 3e-17
Identities = 81/547 (14%), Positives = 197/547 (36%), Gaps = 52/547 (9%)
Query: 4682 EGEGMK-DVSDQIGNEEQVEDTFQKGQEK----DK----EDPDSKSDIKGEDNAIEMSED 4732
EG G K + +++G+ D+ G + DK +DP+S + G D+A S++
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483
Query: 4733 FDGKMHDGELEEQEEDDEK--SDSEGGD-------LDKHMGDLNG------EEADKLDER 4777
D E D SDS+G + D + D NG ++ DK D
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 4778 LWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEA 4837
D + D + N ++ + D DS+ + + DS +S+ D S + + +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSS----DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 4838 EADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGED 4897
+ D D ++ D D +++ D + E+ D DS D N +
Sbjct: 600 NSSDSSDSSDS-SDSSDSSDSSDSKSDS--------SKSESDSSDSDSKSDSSDSNSSDS 650
Query: 4898 TDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEM 4957
+DN + + + + + ++ +++ + S S S+ + E
Sbjct: 651 SDNSDSSDSS---------NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 4958 DTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDT 5017
+D D D++ + + S ++ + + +D + + SD+
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 5018 EEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077
+S ++ ++ + + + ++ + S ++D++ +
Sbjct: 762 SNS-----SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 5078 SNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTD-SHAEQGPAQ 5136
+ + + ++ ++ S ++ S G ++ ++ + +D S +
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 5137 QPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ 5196
+ D++ + SD+ ++ D + + DS + E ++ ++
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Query: 5197 EEFKAAD 5203
+ ++D
Sbjct: 937 DSSNSSD 943
Score = 90.5 bits (223), Expect = 4e-17
Identities = 75/548 (13%), Positives = 184/548 (33%), Gaps = 26/548 (4%)
Query: 4663 DSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKG 4722
DS G G D + G+G+ D SD ++ + D D +S SD
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKS--DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS 582
Query: 4723 EDNAIEMSEDFDGKMHDGELEEQEEDD--EKSDSEGGDLDKHMGDLNGEEADKLDERLWG 4780
D+ S D D + + D + SDS D D + E+D D
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS--SDSSDSKSDSSKSESDSSDSDSKS 640
Query: 4781 DDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEAD 4840
D + + DN + S D+ DS +S+ S D + +++
Sbjct: 641 DSSDSNSSDSSDNSD-------SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 4841 DGGQGEDKINEQIDERDYDENE-VDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTD 4899
D + ++ D D D ++ D + N + D D N +
Sbjct: 694 DSSNSSES-SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 4900 NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
++ + + + + + +D N+S + + + + D + + D+
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812
Query: 4960 GADDQDGDAAQHPE----EHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDS 5015
+D D D++ + S + S + D +G ++ +++ + + S
Sbjct: 813 -SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 5016 DTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEG 5075
D+ + + S + + N+ + + ++ + + S +++++ +
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 5076 HESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPA 5135
+ + +S ++ +D+ S N + D+ + +
Sbjct: 932 NSN------SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 5136 QQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEE 5195
+ +D+ + + + + D ++ ++ DS + + D+ ++
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 5196 QEEFKAAD 5203
+ ++D
Sbjct: 1046 SDSSDSSD 1053
Score = 85.5 bits (210), Expect = 1e-15
Identities = 80/549 (14%), Positives = 193/549 (35%), Gaps = 59/549 (10%)
Query: 4666 GEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDN 4725
G+G D G+ G+G ++ N E + G + + S S+ G D
Sbjct: 393 GKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYD- 451
Query: 4726 AIEMSEDFDGKMHDGEL-----EEQEEDDEKSDSEGGDLDKHMGDLNGEEA----DKLDE 4776
S DFD K G+ E DD S+S+ + N +E+ + D
Sbjct: 452 ----SYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS 507
Query: 4777 RLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE 4836
+ G +D++ D + N ++ G G + D +D DSG D S D +
Sbjct: 508 K--GAEDDDSDSTSDTNNSDSNGNGNNGNDD-----NDKSDSGKGKSDSSDSDSSDSSNS 560
Query: 4837 AEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGE 4896
+++ D + + + D ++ D D + DS D +
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDS------------------DSSDSSDSDSSDSSNSS 602
Query: 4897 DTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEE 4956
D+ + ++ ++ + ++++D ++S+S + S+ + +
Sbjct: 603 DSSDSSDSSDS------------SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650
Query: 4957 MDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSD 5016
D +D D + + + S+ S ++ + +D + + + SD
Sbjct: 651 SD-NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 5017 TEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGH 5076
++ + + ++ + ++ ++ + + + ++ + + S ++D++ +
Sbjct: 710 SDSS-----DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 5077 ESNFIAQLASQKHTRKNTQSFKRKPGQADNERS--MGDHNERVHKRLRTVDTDSHAEQGP 5134
+ + +S N+ +D+ S D + + +DS +
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Query: 5135 AQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTE 5194
+ D+ SD+ D D +++ ++ DS + D+ ++
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 5195 EQEEFKAAD 5203
E ++D
Sbjct: 885 SNESSNSSD 893
Score = 85.5 bits (210), Expect = 1e-15
Identities = 85/580 (14%), Positives = 183/580 (31%), Gaps = 63/580 (10%)
Query: 4657 PKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDS 4716
P E + + A D G+ D S GN KG E D D DS
Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSD-----SKGAEDD--DSDS 517
Query: 4717 KSDIKGED---NAIEMSEDFD------GKMH--DGELEEQEEDDEKSDSEGGDLDKHMGD 4765
SD D N ++D D GK D + + + SDS D
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 4766 LNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDK 4825
+ + +D D + + + + ++ D DS D DS S D
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS----SDSKSDSSKSESDS 633
Query: 4826 SQQDKKEEKEEAEADDGGQGED--------KINEQIDERDYDENEVDPYHGN-------Q 4870
S D K + ++ + D D ++ D D ++ N
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 4871 EKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEA-------GHEAE 4923
+ E+ D D + DS D + ++++ + + N + + + +
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 4924 ERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSV 4983
+ ++ N S S + S D + + + D + +S + S
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813
Query: 4984 EEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQN 5043
+ D ++ + +D + + SD+ + + +S ++ +
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 5044 TQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQ 5103
+ + + + ++ E S +++++ ++ +S+ +S N+
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS----NSSDSSDSSNSSDSSESSNS 929
Query: 5104 ADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTY 5163
+DN S S++ + D+ SD+ D+ +
Sbjct: 930 SDNSNS---------------SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 5164 DVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAAD 5203
D + + DS + + D+ ++ + ++D
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Score = 74.7 bits (182), Expect = 2e-12
Identities = 68/578 (11%), Positives = 179/578 (30%), Gaps = 27/578 (4%)
Query: 4663 DSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVE-----DTFQKGQEKDKEDPDSK 4717
DS+ +++ + D SD + + D+ D D
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 4718 SDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDER 4777
SD ++ + S D + D S+ D D + +D D
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 4778 LWGDDDEEED-----EEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKE 4832
D + D + + N+++ + + S+ D+ DS +SN+ + D +
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 4833 EKEEAEAD--DGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLD-- 4888
+++D D D + + + + + ++ D D N
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 4889 ---SEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP 4945
S+ N + +D+ + + + + + ++ ++S + +
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 4946 SEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQ 5005
+ D + + ++ +D D + + S+ S ++ + + +D
Sbjct: 1017 NSSDSSNSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 5006 PQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGS 5065
+ E SD+ + ++S ++ ++ + + + ++ + S
Sbjct: 1076 SDSSDSSESSDSSD--------SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 5066 GAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVD 5125
++D++ + ++ + +S+ ++ +D+ S +
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 5126 TDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEE 5185
S + + D+ SD+ D+ +S + S D +
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247
Query: 5186 IEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFD 5223
D+ + + +D + KSG G D
Sbjct: 1248 NSSDSSDSSDSSD-STSDSNDESDSQSKSGNGNNNGSD 1284
Score = 72.0 bits (175), Expect = 2e-11
Identities = 100/635 (15%), Positives = 227/635 (35%), Gaps = 70/635 (11%)
Query: 4676 EGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDG 4735
+ G +G+ +DV+ + QV + D ED ++ + E N E++ +
Sbjct: 163 QNGDVGDAGHNEDVAVVQEDGPQVAGS---NNSTDNEDEIIENSCRNEGNTSEITPQINS 219
Query: 4736 KMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKT 4795
K + +E + E LD G +G AD+ ++ GDD++EE +D+
Sbjct: 220 KRNG----TKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSN 275
Query: 4796 EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE------------AEADDGG 4843
G +E + +DD+ S N D + E KE+ +E + G
Sbjct: 276 NSKG----QEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAG 331
Query: 4844 QGEDKINEQI-DERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLD-------------- 4888
ED +++I D + + E K E A+ D ++
Sbjct: 332 IPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKE 391
Query: 4889 -------SEDKN--------GGEDTDNEEGEEENPLEIKEKPEEAGHE--AEERGETETD 4931
EDK G T E E P + E + GH + D
Sbjct: 392 VGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYD 451
Query: 4932 QNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQD---GDAAQHPEEHSEEQQQSVEE--K 4986
+ + P+ D++ G ++ ++ +D+ GDA+ + +E + S + +
Sbjct: 452 SYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAE 511
Query: 4987 DKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQA 5046
D ++D N G ++ + SD+ + ++ + S + + ++ +
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
Query: 5047 MELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
+ + S ++D++ ++ +S+ + + + ++ S ++D+
Sbjct: 572 SD-----SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 5107 ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYD-AQTYDV 5165
+S D ++ K + +DS++ + ++ SD+ D + + D
Sbjct: 627 SKSESDSSDSDSK---SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 5166 ASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEM 5225
++ + DS E + D+ D++ + +++ + S ++
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDS-SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 5226 EVEIQTVKTEEDQDPRTDKAHKETENEKPERSRES 5260
+ D +D ++ ++ + S S
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Score = 70.1 bits (170), Expect = 6e-11
Identities = 64/509 (12%), Positives = 165/509 (32%), Gaps = 32/509 (6%)
Query: 4690 SDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDD 4749
SD + + + + DS G D+ D + +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 4750 EKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSEL 4809
+ SDS + + D + + + D + N ++ + + SE
Sbjct: 878 DSSDSSDSNESSNSSDSSD-----------SSNSSDSDSSDSSNSSDSSDSSNSSDSSE- 925
Query: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKIN--EQIDERDYDENEVDPYH 4867
++ D+ NS+ + D + + + + D D N + D D ++
Sbjct: 926 --SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 4868 GNQEKVPEPEALDLPDDLN-LDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERG 4926
+ + ++ D D N DS D + D+ N + ++ +
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 4927 ETETDQNESQSPQEPEEGPSED--DKAEGEEEMDTGADDQDGDAAQHP-EEHSEEQQQSV 4983
++ + S S + S D D ++ + D+ + D++ S + S
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 4984 EEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQN 5043
+ D + ++ + + + DS ++ + E + + ++ +
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS-DSSDS 1162
Query: 5044 TQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQ 5103
+ + + + ++ + S ++D++ + + + +S ++
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222
Query: 5104 ADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTY 5163
+D+ S D NE + D+ ++ + + +D+ + +D D+Q+
Sbjct: 1223 SDSSDS-SDSNE-------SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS- 1273
Query: 5164 DVASKEQQQSAKDSGKDQEEEEIEDTLMD 5192
S + DS D E + + D
Sbjct: 1274 --KSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 64.7 bits (156), Expect = 2e-09
Identities = 41/284 (14%), Positives = 94/284 (33%), Gaps = 13/284 (4%)
Query: 4690 SDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDD 4749
S + D+ D D SD N+ + S+ D + + D
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 4750 EKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSEL 4809
S+ D + + +D D D + D + N ++ + + S+
Sbjct: 1081 SSESSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGN 4869
D+ DS S+ D + + +++ D D N D ++ +
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 4870 QEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE 4929
+ ++ D D + S+ + + +D+ + E + ++ + ++ ++
Sbjct: 1199 SDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257
Query: 4930 TDQNESQSPQEPEE----------GPSEDDKAEGEEEMDTGADD 4963
+ + S S E + G D +EG + + +DD
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 58.5 bits (140), Expect = 2e-07
Identities = 114/618 (18%), Positives = 230/618 (37%), Gaps = 70/618 (11%)
Query: 4689 VSDQIGNEEQVEDTFQKGQEKDKEDPDSKSD-IKGEDNAIEMSEDFDGKM---------H 4738
V D++ ++++ E D+ ++ D KGE N + +E GK
Sbjct: 44 VQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAE-VGGKSFSTYSTLANE 102
Query: 4739 DGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWG-----------DDDEEED 4787
+G +E D K+++ G D ++G+E + + G +
Sbjct: 103 EGNIEGWNGDTGKAETYGHD------GIHGKEENITANGIQGQVSIIDNAGATNRSNTNG 156
Query: 4788 EEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGED 4847
+++ + + G ED +V +D +G++N S ++ E E + ++G E
Sbjct: 157 NTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNN---STDNEDEIIENSCRNEGNTSE- 212
Query: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDS-EDKNGGEDTDNEEGEEE 4906
I QI+ + E + G E + P D ED+ G+D D E G +
Sbjct: 213 -ITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGK 271
Query: 4907 NPLEIKEKPEEAGHEAEERGETETDQN-ESQSPQEPE--EGPSED---DKAEGEEEMDTG 4960
+ + E H E+ ++ QN +S+ +PE E P + DK EE G
Sbjct: 272 DSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAG 331
Query: 4961 ADDQDG-DAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
+ +G + ++ + + + VE + + E D+G + + + T+E
Sbjct: 332 IPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKE 391
Query: 5020 QVPEALERKEHASCGQTGV----ENMQNT-QAMELAGAAPEKEQGKEEHGSGAADANQAE 5074
V + E KE GQ G+ N++ + + + G + E G + S + ++
Sbjct: 392 -VGKGNEGKEDK--GQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSD 448
Query: 5075 GHESNFIAQLASQ---------------KHTRKNTQSFKRKPGQADNERSMGDHNERVHK 5119
G++S + Q ++ + S R +++ S + N K
Sbjct: 449 GYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSK 508
Query: 5120 RLRTVDTDSHAEQGPAQ---QPQAQVEDADAFEHIKQGSDAYDAQTYDV--ASKEQQQSA 5174
D+DS ++ + +D D + K SD+ D+ + D +S S
Sbjct: 509 GAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD 568
Query: 5175 KDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTT-APLGFDEMEVEIQTVK 5233
DS + + + D+ + + ++D S ++ + D + + + K
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 5234 TEEDQDPRTDKAHKETEN 5251
+E D K+ N
Sbjct: 629 SESDSSDSDSKSDSSDSN 646
Score = 54.3 bits (129), Expect = 3e-06
Identities = 36/214 (16%), Positives = 71/214 (33%), Gaps = 19/214 (8%)
Query: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEE 4747
D SD + + D+ D D SD ++ + SE D + +
Sbjct: 1107 DSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 4748 DDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDS 4807
D S+ D + +D D D + D + + ++ + + S
Sbjct: 1166 SDSSDSSDSSD--------SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217
Query: 4808 ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYH 4867
+ D+ DS +SN+ D + + + + D D + D D +++ +
Sbjct: 1218 DSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Query: 4868 GNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE 4901
GN D + DSE + T ++
Sbjct: 1278 GNNN----------GSDSDSDSEGSDSNHSTSDD 1301
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 90.5 bits (223), Expect = 4e-17
Identities = 92/400 (23%), Positives = 156/400 (39%), Gaps = 22/400 (5%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
+D G F D + G G + + + ++G++E +DT Q +E + DS D
Sbjct: 104 DDEDDSGDDTFGD-DDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTT 162
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
E ++ + D K G+ ++ E +E G D + GD G E D DE + D
Sbjct: 163 SESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD--GSELD--DEGMQSD 218
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE-AEAD 4840
D E E +++ G +E E + + DSG S + K K +E D
Sbjct: 219 DPESIRSERGNSRMNSAGM-KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 277
Query: 4841 DGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN 4900
D + +D + + D EN + + +P D D DS++ E++ N
Sbjct: 278 DRSELDDNNTMEEVKSDSTENS----NSRDTGLSQPRR-DSKGDSQEDSKENLSQEESQN 332
Query: 4901 EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTG 4960
+G E +EA ++E + Q E S + E +E+ D+
Sbjct: 333 VDGPS------SESSQEANLSSQE--NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSS 384
Query: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ 5020
+D + E EEQ S + EE E+ P D+ QE + S E Q
Sbjct: 385 EEDSSHTLSHSKSESREEQADSESSESLNFSEESPES-PEDENSSSQEGLQSHSSSAESQ 443
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 5060
E+ +E S Q + +++ + E ++ E Q K
Sbjct: 444 SEES-HSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 482
Score = 78.6 bits (192), Expect = 2e-13
Identities = 96/496 (19%), Positives = 204/496 (41%), Gaps = 64/496 (12%)
Query: 4727 IEMSEDFDGKMHDGELEEQEEDDEKSDSE---GGDLDKHMGDLNGEEADKLDERLWGDDD 4783
+E SE +G E + E+ + + SE G D +++ L G + + G DD
Sbjct: 45 LESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGK---GGDD 101
Query: 4784 EEEDEEEEDNKT---EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEAD 4840
+++DE++ + T +++GPG D + GNS + ++ +A +
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPG----------PKDRQEGGNSRLGSDEDS--DDTIQASEE 149
Query: 4841 DGGQGEDKINEQIDE-RDYD-ENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNG-GED 4897
QG+D + E R+ D E+ VD + E E+ + D E +G G +
Sbjct: 150 SAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 209
Query: 4898 TDNEEGEEENPLEIKE-----KPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAE 4952
D+E + ++P I+ + AG +++E GE N S G S+ +
Sbjct: 210 LDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS------GGSQLLEHP 263
Query: 4953 GEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEER 5012
+ ++ D ++ + ++ E+ +S ++ + + G D QE+ +
Sbjct: 264 SRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 323
Query: 5013 EDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQ 5072
S E Q + + + EN +Q ++ + + + D++
Sbjct: 324 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383
Query: 5073 AEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQ 5132
+E S HT +++S R+ QAD+E S ++ + +E+
Sbjct: 384 SEEDSS----------HTLSHSKSESREE-QADSESS---------------ESLNFSEE 417
Query: 5133 GPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMD 5192
P + P+ E++ + E ++ S + ++Q+ + S+E ++DS + +E+ ++
Sbjct: 418 SP-ESPED--ENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 474
Query: 5193 TEEQEEFKAADVEQLK 5208
+EE + K ++E K
Sbjct: 475 SEEDGQLKNIEIESRK 490
Score = 62.4 bits (150), Expect = 1e-08
Identities = 94/519 (18%), Positives = 180/519 (34%), Gaps = 76/519 (14%)
Query: 4747 EDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEED 4806
+++E DSE E+ + E +E+ +E+ D+ E G G D+
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ 82
Query: 4807 SEL-VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER-DYDENEVD 4864
+A + +G DK + + DD G G E + R DE+ D
Sbjct: 83 YIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDD 142
Query: 4865 PYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEE 4924
++E P + ++ +DT +E E +N + KPE
Sbjct: 143 TIQASEESAP---------------QGQDSAQDTTSESRELDNEDRVDSKPE-------- 179
Query: 4925 RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE 4984
G T ++ES+ E +G E D G D ++ + E + S
Sbjct: 180 -GGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIR--SERGNSRMNSAG 236
Query: 4985 EKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE---HASCGQTGVENM 5041
K KE+ E + D G E + ++ E +R E + + + ++
Sbjct: 237 MKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST 296
Query: 5042 QNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP 5101
+N+ + + + P ++ + + +Q E + + +SQ+ + ++
Sbjct: 297 ENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQ 356
Query: 5102 GQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQ 5161
+ +E S GD+ + T S+ E ED+D+ E
Sbjct: 357 EEVVSE-SRGDNPD---------PTTSYVEDQ---------EDSDSSE------------ 385
Query: 5162 TYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLG 5221
++ + S + EE+ D+E E ++ PE+ S + L
Sbjct: 386 ------EDSSHTLSHSKSESREEQA-----DSESSESLNFSEESPESPEDENSSSQEGLQ 434
Query: 5222 FDEMEVEIQTVKT---EEDQDPRTDKAHKETENEKPERS 5257
E Q+ ++ E+D D + KE N +S
Sbjct: 435 SHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 473
Score = 48.5 bits (114), Expect = 2e-04
Identities = 38/189 (20%), Positives = 82/189 (43%), Gaps = 24/189 (12%)
Query: 4695 NEEQVEDTFQKGQEKDKEDPDSKS----DIKGEDNAIEMSEDFDGKMHDGE-------LE 4743
++E ++ + + ++ + P S+S ++ ++N+ E E+ + +E
Sbjct: 317 SQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVE 376
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG---- 4799
+QE+ D + L + E+AD +E + E++N + + G
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 436
Query: 4800 -PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDY 4858
+ + E +++D+ DS +S++ K + E K +E D G+ K N +I+ R
Sbjct: 437 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED----GQLK-NIEIESR-- 489
Query: 4859 DENEVDPYH 4867
+ VD YH
Sbjct: 490 -KLTVDAYH 497
Score = 43.9 bits (102), Expect = 0.005
Identities = 41/193 (21%), Positives = 73/193 (37%), Gaps = 5/193 (2%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
EDS + E G E ++S Q + E E+ + + D DP + S ++
Sbjct: 319 EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRG-DNPDPTT-SYVE 376
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
++++ ED + + E +EE + SE + + + +E E L
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 436
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD 4841
E + EE + E+ D +DS +D N S+ ++ Q K E E +
Sbjct: 437 SSSAESQSEESHSEEDDS---DSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTV 493
Query: 4842 GGQGEDKINEQID 4854
I +Q D
Sbjct: 494 DAYHNKPIGDQDD 506
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 90.5 bits (223), Expect = 4e-17
Identities = 92/400 (23%), Positives = 156/400 (39%), Gaps = 22/400 (5%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
+D G F D + G G + + + ++G++E +DT Q +E + DS D
Sbjct: 88 DDEDDSGDDTFGD-DDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTT 146
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
E ++ + D K G+ ++ E +E G D + GD G E D DE + D
Sbjct: 147 SESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD--GSELD--DEGMQSD 202
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE-AEAD 4840
D E E +++ G +E E + + DSG S + K K +E D
Sbjct: 203 DPESIRSERGNSRMNSAGM-KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 261
Query: 4841 DGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN 4900
D + +D + + D EN + + +P D D DS++ E++ N
Sbjct: 262 DRSELDDNNTMEEVKSDSTENS----NSRDTGLSQPRR-DSKGDSQEDSKENLSQEESQN 316
Query: 4901 EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTG 4960
+G E +EA ++E + Q E S + E +E+ D+
Sbjct: 317 VDGPS------SESSQEANLSSQE--NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSS 368
Query: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ 5020
+D + E EEQ S + EE E+ P D+ QE + S E Q
Sbjct: 369 EEDSSHTLSHSKSESREEQADSESSESLNFSEESPES-PEDENSSSQEGLQSHSSSAESQ 427
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 5060
E+ +E S Q + +++ + E ++ E Q K
Sbjct: 428 SEES-HSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 466
Score = 74.7 bits (182), Expect = 2e-12
Identities = 94/502 (18%), Positives = 205/502 (40%), Gaps = 66/502 (13%)
Query: 4723 EDNAIEMSEDFDGKMHDGEL-----EEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDER 4777
++N E SE++ G + E+ + + + G D +++ L G + +
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGK- 81
Query: 4778 LWGDDDEEEDEEEEDNKT---EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEK 4834
G DD+++DE++ + T +++GPG D + GNS + ++
Sbjct: 82 --GGDDKDDDEDDSGDDTFGDDDSGPG----------PKDRQEGGNSRLGSDEDS--DDT 127
Query: 4835 EEAEADDGGQGEDKINEQIDE-RDYD-ENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDK 4892
+A + QG+D + E R+ D E+ VD + E E+ + D E
Sbjct: 128 IQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESS 187
Query: 4893 NG-GEDTDNEEGEEENPLEIKE-----KPEEAGHEAEERGETETDQNESQSPQEPEEGPS 4946
+G G + D+E + ++P I+ + AG +++E GE N S G S
Sbjct: 188 HGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS------GGS 241
Query: 4947 EDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQP 5006
+ + + ++ D ++ + ++ E+ +S ++ + + G D
Sbjct: 242 QLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDS 301
Query: 5007 QEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSG 5066
QE+ + S E Q + + + EN +Q ++ + + +
Sbjct: 302 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED 361
Query: 5067 AADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDT 5126
D++ +E S HT +++S R+ QAD+E S ++
Sbjct: 362 QEDSDSSEEDSS----------HTLSHSKSESREE-QADSESS---------------ES 395
Query: 5127 DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
+ +E+ P + P+ E++ + E ++ S + ++Q+ + S+E ++DS + +E+
Sbjct: 396 LNFSEESP-ESPED--ENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNS 452
Query: 5187 EDTLMDTEEQEEFKAADVEQLK 5208
++ +EE + K ++E K
Sbjct: 453 TESKSSSEEDGQLKNIEIESRK 474
Score = 58.9 bits (141), Expect = 1e-07
Identities = 87/479 (18%), Positives = 166/479 (34%), Gaps = 76/479 (15%)
Query: 4787 DEEEEDNKTEETGPGMDEEDSEL-VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQG 4845
+E+ D+ E G G D+ +A + +G DK + + DD G G
Sbjct: 47 NEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPG 106
Query: 4846 EDKINEQIDER-DYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE 4904
E + R DE+ D ++E P+ + + +DT +E E
Sbjct: 107 PKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQ---------------DSAQDTTSESRE 151
Query: 4905 EENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQ 4964
+N + KPE G T ++ES+ E +G E D G
Sbjct: 152 LDNEDRVDSKPE---------GGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSD 202
Query: 4965 DGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEA 5024
D ++ + E + S K KE+ E + D G E + ++ E
Sbjct: 203 DPESIR--SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEE 260
Query: 5025 LERKE---HASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFI 5081
+R E + + + ++ +N+ + + + P ++ + + +Q E +
Sbjct: 261 DDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGP 320
Query: 5082 AQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQ 5141
+ +SQ+ + ++ + +E S GD+ + T S+ E
Sbjct: 321 SSESSQEANLSSQENSSESQEEVVSE-SRGDNPD---------PTTSYVEDQ-------- 362
Query: 5142 VEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKA 5201
ED+D+ E ++ + S + EE+ D+E E
Sbjct: 363 -EDSDSSE------------------EDSSHTLSHSKSESREEQA-----DSESSESLNF 398
Query: 5202 ADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKT---EEDQDPRTDKAHKETENEKPERS 5257
++ PE+ S + L E Q+ ++ E+D D + KE N +S
Sbjct: 399 SEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 457
Score = 48.5 bits (114), Expect = 2e-04
Identities = 38/189 (20%), Positives = 82/189 (43%), Gaps = 24/189 (12%)
Query: 4695 NEEQVEDTFQKGQEKDKEDPDSKS----DIKGEDNAIEMSEDFDGKMHDGE-------LE 4743
++E ++ + + ++ + P S+S ++ ++N+ E E+ + +E
Sbjct: 301 SQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVE 360
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG---- 4799
+QE+ D + L + E+AD +E + E++N + + G
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 420
Query: 4800 -PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDY 4858
+ + E +++D+ DS +S++ K + E K +E D G+ K N +I+ R
Sbjct: 421 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED----GQLK-NIEIESR-- 473
Query: 4859 DENEVDPYH 4867
+ VD YH
Sbjct: 474 -KLTVDAYH 481
Score = 43.9 bits (102), Expect = 0.005
Identities = 41/193 (21%), Positives = 73/193 (37%), Gaps = 5/193 (2%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
EDS + E G E ++S Q + E E+ + + D DP + S ++
Sbjct: 303 EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRG-DNPDPTT-SYVE 360
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGD 4781
++++ ED + + E +EE + SE + + + +E E L
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 420
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD 4841
E + EE + E+ D +DS +D N S+ ++ Q K E E +
Sbjct: 421 SSSAESQSEESHSEEDDS---DSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTV 477
Query: 4842 GGQGEDKINEQID 4854
I +Q D
Sbjct: 478 DAYHNKPIGDQDD 490
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 84.7 bits (208), Expect = 2e-15
Identities = 84/378 (22%), Positives = 153/378 (40%), Gaps = 34/378 (8%)
Query: 4748 DDEKSDSEGGDLDKHMGDLNGEEA--DKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE 4805
DD+ D G DL+ + + EA D D+ DD+ ++ E +DN + P + +
Sbjct: 125 DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
Query: 4806 DSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDP 4865
DS+ V D++ DS + N D S D ++ + DD D ++ D+ D ++ D
Sbjct: 185 DSD-VPDDNSDDSSDDNSDDSSDDNSDDSD--VPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSE---DKNGGEDTDNEEGEEENPLEIKEKPEEAGHEA 4922
+ + EA PDD + DSE D + + ++ ++ + EA ++
Sbjct: 242 SEAPDDSSDDSEA---PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
Query: 4923 EERGETETDQ-NESQSPQEPEEGPSEDDKAEGEEEMDTGADD--QDGDAAQHPEEHSEEQ 4979
+ E D+ ++S P++ + D + E+ A+D +G A EE E
Sbjct: 299 SDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIAS-DEEELVEA 357
Query: 4980 QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVE 5039
+V + D + ++ GE + +P + E +E ++P E + Q+G
Sbjct: 358 AAAVSQHD--SSDDAGEQDLGENLSKPPSDPEANPEVSERKLP--TEEEPAPVVEQSGKR 413
Query: 5040 NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQ---- 5095
+ +E P K Q K ++ Q + N + L +K KN
Sbjct: 414 KSKTKTIVE----PPRKRQTKTKNIVEPPRKRQTK--TKNIVEPLRKRKAKTKNVSVTPG 467
Query: 5096 -----SFKRKPGQADNER 5108
K+KPG A E+
Sbjct: 468 HKKRGPSKKKPGAAKVEK 485
Score = 81.3 bits (199), Expect = 3e-14
Identities = 86/446 (19%), Positives = 186/446 (41%), Gaps = 41/446 (9%)
Query: 4786 EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDK--KEEKEEAEADDGG 4843
+D+ ++DN + P + +DSE A DDN D + D S + + +++EA D
Sbjct: 125 DDDNDDDNGNDLEVPDDNSDDSE--APDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 182
Query: 4844 QGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEG 4903
+ + + + D+N D N + D+PDD S+D + +D+ ++
Sbjct: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSDD------SDVPDD---KSDDSDVPDDSSDDSD 233
Query: 4904 EEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP---SEDDKAEGEEEMDTG 4960
++ + E P+++ ++E ++ D + E P S+D +A + D+
Sbjct: 234 VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
Query: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQE--EEEREDSDTE 5018
A D D ++ P++ S++ E+K ++D + + ++ E + SD E
Sbjct: 294 ASDDSSDDSEAPDDKSDDSDVP-EDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE 352
Query: 5019 EQVPEALERKEHASCGQTGVENMQNTQAMELAG--AAPEKEQGK---EEHGSGAADANQA 5073
E V A +H S G +++ + + A PE + K EE + + +
Sbjct: 353 ELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGK 412
Query: 5074 EGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQG 5133
++ I + ++ T+ + Q + + +R K T H ++G
Sbjct: 413 RKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRG 472
Query: 5134 PAQQP--QAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKD--QEEEEIEDT 5189
P+++ A+VE K+ + + ++ ++S K SGK+ + ++E+
Sbjct: 473 PSKKKPGAAKVE--------KRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQR 524
Query: 5190 LMDTEEQEEFKAADVEQLKPEEIKSG 5215
+ D F + ++ PE+++ G
Sbjct: 525 IYDL-----FNRSVCDKKLPEKLRIG 545
Score = 79.0 bits (193), Expect = 1e-13
Identities = 61/288 (21%), Positives = 115/288 (39%), Gaps = 33/288 (11%)
Query: 4710 DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
D D D+ +D++ D+ + SE D D E + DD ++ + D D D N +
Sbjct: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD-DSEAPDDNSD 184
Query: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELV--AKDDNLDSGNSNKDKSQ 4827
++D D+ D+ D+ +DN + P +DS++ + DD+ +S+ D
Sbjct: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
Query: 4828 QDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALD------- 4880
D + EA DD + ++ D+ + ++ D + + + EA D
Sbjct: 245 PDDSSDDSEA-PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
Query: 4881 LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHE------------------- 4921
PDD + DS+ D + + + LE+ E+ +E
Sbjct: 304 APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ 363
Query: 4922 ---AEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDG 4966
+++ GE + +N S+ P +PE P ++ EE +Q G
Sbjct: 364 HDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSG 411
Score = 72.8 bits (177), Expect = 9e-12
Identities = 55/255 (21%), Positives = 108/255 (42%), Gaps = 23/255 (9%)
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSE------------LVAKDDNLDSGNSNKDKSQQD 4829
D +EE E+ K + D+E E +V DD+ D N N D D
Sbjct: 82 DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGN-DLEVPD 140
Query: 4830 KKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDS 4889
+ EA D+ E + D D+N D ++ + D+PDD + DS
Sbjct: 141 DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD----SEAPDDNSDDSDVPDDNSDDS 196
Query: 4890 EDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDD 4949
D N + +D+ + + P +K +++ + +++ + S + P++ S+D
Sbjct: 197 SDDNSDDSSDDNSDDSDVP---DDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS-SDDS 252
Query: 4950 KAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKD-KEADEEGGENGPADQGFQPQE 5008
+A + D+ A D D ++ P++ S++ + S + D EA ++ ++ A + +
Sbjct: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD-KSDD 311
Query: 5009 EEEREDSDTEEQVPE 5023
+ ED + VP+
Sbjct: 312 SDVPEDKSDDSDVPD 326
Score = 51.6 bits (122), Expect = 2e-05
Identities = 63/305 (20%), Positives = 111/305 (36%), Gaps = 30/305 (9%)
Query: 4656 LPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPD 4715
+P + +DS+ + + + D + D SD + D + + D
Sbjct: 188 VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDD 247
Query: 4716 SKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775
S D + D++ + SE D D E + DD ++ + D D D D D
Sbjct: 248 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSD-DSEASD------DSSD 300
Query: 4776 ERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKE 4835
+ DD ++ + ED + P + +D E+ ++L N+ + D++E E
Sbjct: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDL----CNEGQIASDEEELVE 356
Query: 4836 EAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGG 4895
A A D EQ D EN P + E PE LP + + G
Sbjct: 357 AAAAVSQHDSSDDAGEQ----DLGENLSKP-PSDPEANPEVSERKLPTEEEPAPVVEQSG 411
Query: 4896 EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET-------------DQNESQSPQEPE 4942
+ + E P + + K + +R +T+T +N S +P +
Sbjct: 412 KRKSKTKTIVEPPRKRQTKTKNIVEPPRKR-QTKTKNIVEPLRKRKAKTKNVSVTPGHKK 470
Query: 4943 EGPSE 4947
GPS+
Sbjct: 471 RGPSK 475
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 84.0 bits (206), Expect = 4e-15
Identities = 138/623 (22%), Positives = 256/623 (41%), Gaps = 100/623 (16%)
Query: 4706 GQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGD 4765
G K++E SK K E + +DFD ELEE + + ++ + +
Sbjct: 30 GAAKEQEPQKSKGKKKKE----KKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTE 85
Query: 4766 LNGEEADKLDERLWG--------DDDEEEDEEEEDNKTEETGPGM--------DEEDSEL 4809
N EE D++ G DD++ E+ E++D+K+++T D++D
Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNK 145
Query: 4810 VAKDDNLDSGNSNK--DKSQQDK---KEEKEEAEADDGGQGEDKINEQIDERDYDENEVD 4864
+ K + SNK D S++D+ K+ KE + + G+ D+ +E + R +
Sbjct: 146 LPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKK--- 202
Query: 4865 PYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAG--HEA 4922
NQ+ P P +D +D + T ++ E+ E K++ EE +
Sbjct: 203 ----NQKNKPGPNIESGNED-----DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKL 253
Query: 4923 EERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQS 4982
+E+ E ET + + QS Q+ + E++ + + +DTG + A+ P ++ +
Sbjct: 254 KEKEELETGKKD-QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312
Query: 4983 VEEKDK-------EADEEGGENGPADQGFQP--------QEEEEREDSDTEEQVP--EAL 5025
++KDK E E+ + GP+ + +EEEER+ + EE++ E L
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL 372
Query: 5026 E--RKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK-----EEHGSGAADAN----QAE 5074
E RKE Q E + + E K++GK + A+A QA+
Sbjct: 373 EAKRKEEERLEQ---EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQ 429
Query: 5075 GHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGP 5134
G E L ++ ++ + K+ P Q +++ + E P
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKR-KKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 5135 AQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASK---------EQQQSAKDSGKDQEEEE 5185
+P+ + + DA G D ++A D ++ E +++ ++ +++EEEE
Sbjct: 489 PVEPEEEEDTEDA------GLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542
Query: 5186 IEDTLMDTEEQE---EFKAADVEQLK-PEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPR 5241
++ + EE+E E D E K +E SG T + E+ + + D R
Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLD---KKPSKEMSSDSEYDSDDDR 599
Query: 5242 T------DKAHKETENEKPERSR 5258
T DKA + E + E S+
Sbjct: 600 TKEERAYDKAKRRIEKRRLEHSK 622
Score = 77.8 bits (190), Expect = 3e-13
Identities = 119/599 (19%), Positives = 248/599 (41%), Gaps = 50/599 (8%)
Query: 4735 GKMHDGELEEQEEDDEKSDS-----EGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEE 4789
GK + E+ +DD D+ EG K + K +++ D+++ +E
Sbjct: 2 GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKI 4849
E+ E G D E + V +N + ++KDK ++ +K +K+ + +D + EDK
Sbjct: 62 LEELSLEAQGIKADRE-TVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD 120
Query: 4850 NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPL 4909
++ + + +V+ Y G+ + + + LP ++ N + D E +E+N
Sbjct: 121 SK---SKKTAKPKVEMYSGSDD---DDDFNKLPKKAKGKAQKSN--KKWDGSEEDEDNSK 172
Query: 4910 EIKEKPE-----EAGHEAEERGETETDQ--NESQSPQEPEEGPSEDDKAEGEEEMDTGAD 4962
+IKE+ E+G E++E ++ Q N+ P E +EDD A ++ T A
Sbjct: 173 KIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDA--SFKIKTVAQ 230
Query: 4963 DQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ-- 5020
+ + ++ EE+ + + K+KE E G ++ + Q + EEE S
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 5021 -VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESN 5079
+P + E+ E + + +N + + + EKE+ ++E G + A E+
Sbjct: 291 VIPASEEKAETPTAAED--DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA- 347
Query: 5080 FIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ 5139
+A+L ++ +K + + K + + + ER+ + R E+ + +
Sbjct: 348 -LAKLKEEEERQKREEEERIK--RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Query: 5140 AQV---EDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ 5196
++ +A + AQ +V SK+ + +D++ ++I L E
Sbjct: 405 GKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVS 464
Query: 5197 EEFK---AADV-EQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENE 5252
E + A +V EQ PE+ +E ++ + E+ +D D +E
Sbjct: 465 ESMELCAAVEVMEQGVPEK-----------EETPPPVEPEEEEDTEDAGLDDWEAMASDE 513
Query: 5253 KPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAE 5311
+ E+ + +H + + + ++ + E E + E G+ E+EKV+ E
Sbjct: 514 ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572
Score = 75.1 bits (183), Expect = 2e-12
Identities = 84/384 (21%), Positives = 163/384 (42%), Gaps = 34/384 (8%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFD-GKMHDGELEEQEEDDEKSDS 4754
E++ +T +K Q K KE S K E+ ++ D G + E + + + D+
Sbjct: 255 EKEELETGKKDQSKQKE-----SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDN 309
Query: 4755 EGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEED-NKTEETGPGMDEEDSELVAKD 4813
EG K GE+ +K E+ G +E K +E E+ E + +
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRL 369
Query: 4814 DNLDSGNSNKDKSQQDKKEEKEEAEADDGG----QGEDKINEQIDERDYDENEVDPYHGN 4869
+ L++ +++ +Q+K+E K++ E + +G+ Q + R E +
Sbjct: 370 EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQ 429
Query: 4870 QEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE 4929
+VP ++L + D + K + +++E E L A E E+G E
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELC-------AAVEVMEQGVPE 482
Query: 4930 TDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQ----------HPEEHSEEQ 4979
+ E+ P EPEE ED + G ++ + A D++ + + +PEE EE+
Sbjct: 483 KE--ETPPPVEPEE--EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Query: 4980 QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVE 5039
++ EE+D+E++EE E G ++ +E+E+ D + + KE +S + +
Sbjct: 539 EE--EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSD 596
Query: 5040 NMQNTQAMELAGAAPEKEQGKEEH 5063
+ + + A E+ + EH
Sbjct: 597 DDRTKEERAYDKAKRRIEKRRLEH 620
Score = 73.6 bits (179), Expect = 5e-12
Identities = 81/382 (21%), Positives = 165/382 (43%), Gaps = 55/382 (14%)
Query: 4691 DQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDE 4750
D G++++ + +KG++++KE K K A++ + L + +E++E
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA-----------LAKLKEEEE 356
Query: 4751 KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNK---------------- 4794
+ E + K + +L + K +ERL + E + ++E++ K
Sbjct: 357 RQKREEEERIKRLEELEAKR--KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Query: 4795 ----TEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ---DKKEEKEEAEADDGGQGED 4847
E T + + E+ +KD +DK ++ + E KE +E+ + +
Sbjct: 415 ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVE 474
Query: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEEN 4907
+ + + E++ V+P +E+ E LD D E E+T+ EG + +
Sbjct: 475 VMEQGVPEKEETPPPVEP---EEEEDTEDAGLD-------DWEAMASDEETEKVEGNKVH 524
Query: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
+E+KE PEE EE E E +++E +E EEG SE +EG+EE + +D++D
Sbjct: 525 -IEVKENPEE-----EEEEEEEEEEDEESEEEEEEEGESEG--SEGDEEDEKVSDEKDSG 576
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALER 5027
+ E S + D + +E A + + + E ++ +TE+ +
Sbjct: 577 KTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICV 636
Query: 5028 KEHASCGQTGV-ENMQNTQAME 5048
H G+T + + +++T +
Sbjct: 637 LGHVDTGKTKILDKLRHTHVQD 658
Score = 71.6 bits (174), Expect = 2e-11
Identities = 83/411 (20%), Positives = 167/411 (40%), Gaps = 57/411 (13%)
Query: 4704 QKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHM 4763
QK +K+K P+ +S + +D + ++ K E E ++ D+EK+ + +
Sbjct: 200 QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKL------RKL 253
Query: 4764 GDLNGEEADKLDERLWGDDDEEEDEEEEDNK-TEETG--PGMDEE-DSELVAKDDNLDSG 4819
+ E K D+ + + +EE +K T +TG P +E+ ++ A+DDN
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDK 313
Query: 4820 NSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL 4879
K ++ +KEEKE+ + + K ++ + +E E ++K E E +
Sbjct: 314 KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE-------RQKREEEERI 366
Query: 4880 DLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAG-------HEAEERGETETDQ 4932
++L +++ E + E +++ E KE+ ++ G EA R E
Sbjct: 367 KRLEELEAKRKEEERLEQ-EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425
Query: 4933 NESQSPQEPEEG-----------------PSEDDKAEGEEEMDTGA----------DDQD 4965
++Q + P + P + + E E M+ A + ++
Sbjct: 426 LQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE 485
Query: 4966 GDAAQHPEEHSEEQQQSVEE-----KDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQ 5020
PEE + + +++ D+E ++ G + P+EEEE E+ + E++
Sbjct: 486 TPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDE 545
Query: 5021 VPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADAN 5071
E E +E S G G E + + +G +K+ KE D++
Sbjct: 546 ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSD 596
Score = 37.0 bits (84), Expect = 0.55
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 14/125 (11%)
Query: 4671 EFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMS 4730
E D E G+ + E M SD+ E+VE K + KE+P+ + + + E+ E S
Sbjct: 494 EEEDTEDAGLDDWEAM--ASDE--ETEKVEGN--KVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 4731 EDFDGKMHDGELEEQEEDDEKSDSE---GGDLDKHMGDLNGEEADKLDERLWGDDDEEED 4787
E+ + + + E E +E+DEK E G LDK + D DDD ++
Sbjct: 548 EEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK-----KPSKEMSSDSEYDSDDDRTKE 602
Query: 4788 EEEED 4792
E D
Sbjct: 603 ERAYD 607
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 83.2 bits (204), Expect = 7e-15
Identities = 73/357 (20%), Positives = 160/357 (44%), Gaps = 28/357 (7%)
Query: 4684 EGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE 4743
E ++++ +++ +E++ + +K QE++K K + E A ++ + + ++
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIR 447
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMD 4803
EQE+ + + + + +K + EE + E +W +++ ++EE + E+
Sbjct: 448 EQEKKMWRQEEKIHEQEK----IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM----- 498
Query: 4804 EEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEA---------EADDGGQGEDKINEQ-- 4852
E E + K + K + Q++K E+EE E ++ + E+K++EQ
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
I E + + + D +EK+ E E + + +++ E + +EE E +
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 4913 EKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHP 4972
EK +E + E+ E +Q E QE + G E+ E EE+M + +
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM-----QEQEETMWRQ 673
Query: 4973 EEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE 5029
EE EQ++ + E++++ E+ ++ QEE+ E + ++ E + R+E
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 79.3 bits (194), Expect = 1e-13
Identities = 116/597 (19%), Positives = 255/597 (42%), Gaps = 55/597 (9%)
Query: 4730 SEDFDGKMHD-----GELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDE 4784
+ D ++HD GELE+ + D+++ +L +E D L L+ +
Sbjct: 160 ARDLISRLHDSWKFAGELEQALSAVATQKKKA---DRYIEELT-KERDALSLELYRNTIT 215
Query: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ 4844
+E+ +E++ K +E ++ E SE+ N+ ++++ +++ +AEAD G+
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQL---NVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 4845 GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE 4904
++ ++ + +ENE+ N+ + E + ++ + E+K ++ E E
Sbjct: 273 ELQSVSAKL-QAQVEENEL----WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 4905 EE--NPLEIKEKPEEAGHEAEERGETETD---QNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
E+ E + EE E EE+ + + + E + ++ E +++K +EEM
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 4960 GADD--QDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDT 5017
++ ++ + H +E EQ++ +E++K ++E + A Q ++ E+E+
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 5018 EEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077
E++ + + R+E Q + + Q E EK +EE + + HE
Sbjct: 448 EQE--KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-----IWRQKEKMHE 500
Query: 5078 SNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRT-VDTDSHAEQGPAQ 5136
+ +K R+ + +++ + E M E++ ++ + + EQ
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 5137 QPQAQVEDADAF----EHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMD 5192
+ + + E D E I++ + Q + +E+++ ++ ++EE+I +
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 5193 TEEQEEFKAADVEQLK-PEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETEN 5251
+EQEE E+++ EE+ +G E ++ Q K +E ++ + K E
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680
Query: 5252 EKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKV 5308
EK R +E I ++ E+ QE E +MW+ E +EEK+
Sbjct: 681 EKKIREQEEKI----------------REQEEMMQEQEE--KMWEQEEKMCEQEEKM 719
Score = 64.7 bits (156), Expect = 2e-09
Identities = 104/544 (19%), Positives = 226/544 (41%), Gaps = 46/544 (8%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFD-GKMHDGELEEQEEDDEKSDS 4754
+E++++ K QEK + KS+I + N E+ + K+ L Q++ ++D
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKL----LLPQQQLQAEADH 269
Query: 4755 EGGDLDKHMGDLNGE-EADKL--------DERLWGDDDEEEDEEEEDNKTEETGPGMDE- 4804
G +L L + E ++L +E++W +++ ++ EE+ + EE +E
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 4805 --EDSELVAKDDNLDSGNSNKDKSQQD---KKEEKEEAEADDGGQGEDKINEQID---ER 4856
E E + + + + K + Q++ +KEEK + + + E+K+ Q + E+
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 4857 DYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT--DNEEGEEENPLEIKEK 4914
+ E++ QEK+ E E ++ + E + E EE E +I+E+
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 4915 PEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADD--QDGDAAQHP 4972
++ + E+ E E + E + QE EE +++K +EE+ + + + +
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 4973 EEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHAS 5032
EE Q++ + E++++ E+ + ++ + QEE RE+ EQ E K
Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 5033 CGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADA---NQAEGHESNFIAQLASQKH 5089
+ + + + E EK + +EE + + + E Q +K
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 5090 TRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFE 5149
+ + +++ + E MG+ E++ EQ Q Q + E
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKM------------CEQEEKMQEQEETMWRQE-E 675
Query: 5150 HIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKP 5209
I++ Q + +E+ ++ ++EE++ + +EQEE E++
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
Query: 5210 EEIK 5213
+E++
Sbjct: 736 QEVR 739
Score = 57.8 bits (138), Expect = 3e-07
Identities = 73/348 (20%), Positives = 146/348 (41%), Gaps = 64/348 (18%)
Query: 4696 EEQVEDTFQKGQEKDK------EDPDSKSDIKGEDNAIEMSEDF--DGKMHDGE------ 4741
EE++ + +K +E++K E + I+ E+ E E + + K+H+ E
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 4742 --LEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEE--------- 4790
+ EQEE K + + ++ + + E+ + +E++W +++ ++EE
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQE-EKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 4791 EDNKTEETGPGMDEEDS-----ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQG 4845
E K E ++ED E + + + K + Q++K++E+EE +
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM----WKQ 610
Query: 4846 EDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEE 4905
E+KI EQ ++ E ++ +EK+ E E + + + +++ E + + +E
Sbjct: 611 EEKIREQEEKIQEQEEKI---REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 4906 ENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQD 4965
E +EK E + E+ E +Q E QE + E EE+M
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE-------EKMWEQEEKMC------- 713
Query: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE 5013
EE+ Q EEK + +E+ E + + QEE+ +E
Sbjct: 714 ---------EQEEKMQEQEEKMRRQEEKMWEQ---EVRLRQQEEKMQE 749
Score = 40.4 bits (93), Expect = 0.050
Identities = 69/392 (17%), Positives = 161/392 (41%), Gaps = 55/392 (14%)
Query: 4971 HPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEH 5030
HP+ + + + K K+ + G E+E++ +E + LE + H
Sbjct: 71 HPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVH 130
Query: 5031 A----SCGQTGVENMQNTQAMELAGAAPEKEQGK-EEHGSGAADANQAEGHESNFIAQLA 5085
+C +T ++ A+ + A ++ +G+ + S D+ + G ++ +A
Sbjct: 131 TIRILTCQKTELQ-----MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVA 185
Query: 5086 SQKHTRKNTQSFKRKPGQAD-----------NERSMGDHNERVHKRLRTVDTDSHAEQGP 5134
+QK +K + + + D + + + N ++ ++L+ V+++ Q
Sbjct: 186 TQK--KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 243
Query: 5135 AQQPQAQVEDADAF---EHIKQGSDAYDAQTYDVASKEQQQSAKDS-----GKDQE---- 5182
++ + ++E A + ++ +D + V++K Q Q ++ + QE
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 5183 --EEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDE-----------MEVEI 5229
EE+I++ +EQEE E+++ +E K + +++ E E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 5230 QTVKTEEDQDPRTDKAHKETEN--EKPERSR--ESTIHTAHQFLMDTIFQPFLKDVNELR 5285
+ + EE + +K ++ E EK E+ R E +H + + + + E
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 5286 QELERQLEMWQPRESGNPEEEKVAAE---MWQ 5314
+ E++ +MW+ E +EEK+ + MW+
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 82.8 bits (203), Expect = 9e-15
Identities = 77/356 (21%), Positives = 141/356 (39%), Gaps = 39/356 (10%)
Query: 4661 MEDSAGEGA---TEFHDYEGGGIGEG--EGMKDVSDQIGNEEQVEDTFQKGQEKDKE--- 4712
MED G A E D + G + E S+ G+E ++ GQ +KE
Sbjct: 4 MEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFG 63
Query: 4713 ---DPDSKSDIKGEDNAIEMSED---------------FDGKMHDGELEEQEEDDEKSDS 4754
+ + S G DN E S++ D H G +++DE S
Sbjct: 64 DDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRS 123
Query: 4755 EGGDLDKHMGDLNGEEADKLDERLWGDD---DEEEDEEEEDNKTEETGPGMDEEDSELVA 4811
+GG H + G E D+ WG + D+ +DE+ +++ EE G DE+ +L
Sbjct: 124 DGGS---HHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDED--KLQN 178
Query: 4812 KDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQE 4871
DD+ N++ ++ Q +E+++ ++ +D+ D D +N D Q
Sbjct: 179 SDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDE---EQP 235
Query: 4872 KVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETD 4931
++ + E + DD + D+ D EE + ++ E+ + + +D
Sbjct: 236 QLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASD 295
Query: 4932 QNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQD--GDAAQHPEEHSEEQQQSVEE 4985
+ P++ D G +++ +G+D +D Q +E+ Q Q EE
Sbjct: 296 SEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEE 351
Score = 76.3 bits (186), Expect = 8e-13
Identities = 101/464 (21%), Positives = 192/464 (41%), Gaps = 80/464 (17%)
Query: 4763 MGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGN-S 4821
M DL G +AD ER D + D ++E+ + G + + +D+ DSG S
Sbjct: 4 MEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESD------QDERGDSGQPS 57
Query: 4822 NKDKSQQDKKEE--KEEAEADDGGQGED---KINEQIDERDYDENEVDPYHGNQEKVPEP 4876
NK+ D ++E + +D+ + D + +E+ D D D ++VD + G++
Sbjct: 58 NKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEA----- 112
Query: 4877 EALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQ 4936
P+D + +GG EG E+ H +E+ E Q
Sbjct: 113 -----PNDDEDEGHRSDGGSHHSEAEGSEK------------AHSDDEKWGRE--DKSDQ 153
Query: 4937 SPQEPEEGPSEDDKAEG--EEEMDTGADD---QDGDAAQHPEEHSEEQQQSVEEKDKEAD 4991
S E + ++++A+G E+++ DD Q+ D + P+ +E+QQ EE+ +D
Sbjct: 154 SDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSD 213
Query: 4992 EEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAG 5051
+E + ++E+++SD EEQ P+ + E MQN+ E
Sbjct: 214 DE--------RPVASDNDDEKQNSDDEEQ-PQLSDE-----------EKMQNSDD-ERPQ 252
Query: 5052 AAPEK-----EQGKEEHGSGAADANQAEGH-----ESNFIA---QLASQKHTRKNTQSFK 5098
A+ E+ ++ +++H S +A + +E N IA + S K+
Sbjct: 253 ASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTM 312
Query: 5099 RKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQ--PQAQVEDADAFEHIKQGSD 5156
G AD+ S D ++ + VD + + ++ P+ ++E + G+D
Sbjct: 313 DLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGND 372
Query: 5157 AYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFK 5200
Y + + S E + +D+ E+E ++D E + K
Sbjct: 373 LYFVKLPNFLSVEPRPFDPQYYEDEFEDE---EMLDEEGRTRLK 413
Score = 75.1 bits (183), Expect = 2e-12
Identities = 83/386 (21%), Positives = 146/386 (37%), Gaps = 70/386 (18%)
Query: 4686 MKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQ 4745
M D+ D G++ E + D D ++ G NA D D + G+ +
Sbjct: 1 MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGS-NASGSESDQDERGDSGQPSNK 59
Query: 4746 EEDDEKSDSEGGDLDKHMG-DLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDE 4804
E + S+ EG H G D + E +D E D E+ D + D + P DE
Sbjct: 60 ELFGDDSEDEGAS--HHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDE 117
Query: 4805 EDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQG-EDKINEQIDERDYDENEV 4863
D G+ + S + E E+A +DD G EDK ++ DE+ + ++
Sbjct: 118 ------------DEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDE 165
Query: 4864 DPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEE-----GEEENPLEIKEKPEEA 4918
+ G+ E D +S+D ++TD+EE +E L +EK
Sbjct: 166 ERAQGSDE------------DKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKA--- 210
Query: 4919 GHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEE 4978
+++ +D ++ + + EE P D EE +DD+ A+ HS++
Sbjct: 211 --NSDDERPVASDNDDEKQNSDDEEQPQLSD-----EEKMQNSDDERPQASDEEHRHSDD 263
Query: 4979 QQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGV 5038
+++ Q + E SD+E++V + AS +
Sbjct: 264 EEE-----------------------QDHKSESARGSDSEDEVLRMKRKNAIASDSEADS 300
Query: 5039 EN---MQNTQAMELAGAAPEKEQGKE 5061
+ N+ M+L G A + G +
Sbjct: 301 DTEVPKDNSGTMDLFGGADDISSGSD 326
Score = 66.2 bits (160), Expect = 8e-10
Identities = 82/316 (25%), Positives = 140/316 (44%), Gaps = 65/316 (20%)
Query: 4664 SAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEE-QVEDTFQKGQEKDKE-----DPDSK 4717
S EG+ + H + E G +D SDQ +E+ Q D ++ Q D++ D D K
Sbjct: 130 SEAEGSEKAHSDD-----EKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEK 184
Query: 4718 SDIKGEDNAIEMSEDFDGKMHDGELEEQEE--------DDEKSDSEGGDLDKHMGDLNGE 4769
++ ++S+D ++ + E ++ DDEK +S+ D+ L+ E
Sbjct: 185 MQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSD----DEEQPQLSDE 240
Query: 4770 E--ADKLDERLWGDDDE---EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKD 4824
E + DER D+E +DEEE+D+K+ E+ G D ED L K N + +S D
Sbjct: 241 EKMQNSDDERPQASDEEHRHSDDEEEQDHKS-ESARGSDSEDEVLRMKRKNAIASDSEAD 299
Query: 4825 KSQQDKKEEKEEAE----ADD---GGQGEDK---INEQIDER--DYDENEVDPYHGNQEK 4872
+ K+ + ADD G GEDK + +DE D+ E +P + +
Sbjct: 300 SDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIE 359
Query: 4873 VPEPEA----------LDLPDDLNLDS--------EDKNGGEDTDNEEG------EEENP 4908
V P+ + LP+ L+++ ED+ E+ +EEG + EN
Sbjct: 360 VEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENT 419
Query: 4909 LEIKEKPEEAGHEAEE 4924
+ + + +E G+E +E
Sbjct: 420 IRWRIRRDEEGNEIKE 435
Score = 44.3 bits (103), Expect = 0.003
Identities = 53/257 (20%), Positives = 99/257 (38%), Gaps = 41/257 (15%)
Query: 5048 ELAGAAPEKEQGKEEHGSG---------AADANQAEGHESNFIAQLASQKHTRKNTQSFK 5098
+L G+ + E +++ SG AA + A G ES+ + S + + K
Sbjct: 6 DLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDD 65
Query: 5099 RKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ-----AQVEDADAFEHIKQ 5153
+ A + +H+ER R + H + P+ Q A +D D
Sbjct: 66 SEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDG 125
Query: 5154 GSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI--------------EDTLMDTEEQEEF 5199
GS +A+ + A + ++ ++ DQ ++E ED L ++++ E+
Sbjct: 126 GSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKM 185
Query: 5200 KAADVE-----------QLKPEE-IKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHK 5247
+ D E QL EE S P+ D + E Q EE ++ +
Sbjct: 186 QNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDN-DDEKQNSDDEEQPQLSDEEKMQ 244
Query: 5248 ETENEKPERSRESTIHT 5264
+++E+P+ S E H+
Sbjct: 245 NSDDERPQASDEEHRHS 261
Score = 34.7 bits (78), Expect = 2.7
Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 18/142 (12%)
Query: 4704 QKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE---------EQEEDDEKSDS 4754
Q+ + KE+ ++ I+ E M E K H L ++EE+ E+S S
Sbjct: 531 QRTEMIKKEEERLRASIRRESQQRRMRE----KQHQRGLSASYLEPDRYDEEEEGEESIS 586
Query: 4755 EGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDD 4814
+++ G + E A R++ D +E EE++ + + +E+ E K
Sbjct: 587 LAAIKNRYKGGIREERA-----RIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRK 641
Query: 4815 NLDSGNSNKDKSQQDKKEEKEE 4836
D +NK + +E+EE
Sbjct: 642 AEDDDKANKKHKKYVISDEEEE 663
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 82.0 bits (201), Expect = 1e-14
Identities = 114/532 (21%), Positives = 213/532 (40%), Gaps = 74/532 (13%)
Query: 4794 KTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQI 4853
K+EE +++ + E V ++ + ++ +++++KE KEE ++ G GE+
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEG-GEE------ 491
Query: 4854 DERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKE 4913
+E + E E + PE EA + E K+ E E+ E ++P E+K
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKS-----PVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 4914 KPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPE 4973
PE+A A+E E++SP E + E+ K+ E + A + A+ P
Sbjct: 547 -PEKAKSPAKE---------EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 4974 EHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASC 5033
E +S E+ EE PA+ P +EE + ++ + KE A
Sbjct: 597 E-----AKSPEKAKSPVKEEA--KSPAEAK-SPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 5034 GQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGA---ADANQAEGHESNFIAQLASQKHT 5090
+ +PEKE+ K + + A+A E +S A+ S +
Sbjct: 649 PEKA--------------KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 5091 RKNTQSFKRKPGQADNE-RSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFE 5149
+ + + P +A + + E+ ++ + P ++ E A + E
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 5150 HIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ------------E 5197
A+T DV S E + AK+ + ++ E +E+ E
Sbjct: 755 K---------AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 5198 EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERS 5257
+ KA + E K EE+KS E++V+ K EE++ P T K TE +K +
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK----TEEKKDSKK 861
Query: 5258 RESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVA 5309
E+ A + ++ +P ++ E + E +++ E ++ PE+E A
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE-EAEDKKKVPTPEKEAPA 912
Score = 72.4 bits (176), Expect = 1e-11
Identities = 101/485 (20%), Positives = 181/485 (37%), Gaps = 78/485 (16%)
Query: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEE-KEEAEAD 4840
++EE++ +EE+ K EE G + E E K + S + +++ KEE K AEA
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 4841 DGGQGEDKINEQID--ERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT 4898
+ E K ++ E+ + + + K PE E P ++ + K+ ++
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE- 590
Query: 4899 DNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMD 4958
E ++P E K PE+A +E E++SP E + E+ K+ E +
Sbjct: 591 -----EAKSPAEAKS-PEKAKSPVKE---------EAKSPAEAKSPVKEEAKSPAEVKSP 635
Query: 4959 TGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTE 5018
A + A+ PE+ +++ + +K E ++ P + E + +
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 5019 EQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHES 5078
V E + E A +P KE+ K + + +A+ E
Sbjct: 696 SPVKEEAKSPEKAK--------------------SPVKEEAKSPEKAKSPVKEEAKTPE- 734
Query: 5079 NFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQP 5138
K E + + ++ +T+D S + PA++
Sbjct: 735 ---------------------KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Query: 5139 QAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEE 5198
D K A +V S E+ +S E+EI ++EE
Sbjct: 774 ARSPAD-------KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI-------PKKEE 819
Query: 5199 FKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKA-HKETENEKPERS 5257
K+ E+ KP+E+K P E E T KTEE +D + ++A KE K E
Sbjct: 820 VKSPVKEEEKPQEVK--VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 5258 RESTI 5262
+E +
Sbjct: 878 KEPAV 882
Score = 70.9 bits (172), Expect = 3e-11
Identities = 111/599 (18%), Positives = 229/599 (38%), Gaps = 78/599 (13%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDS- 4754
EEQ E+T + ++E+ ++K + E+ GE EE E +E++ S
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEG-------------GEEEEAEGGEEETKSP 504
Query: 4755 ---EGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVA 4811
E +K EEA E + +E + E + + P +E S A
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 4812 KDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQE 4871
K + S + +K + + EA + + + ++ ++ + +E
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 4872 KVPEPEALDLPDDLNLDS-EDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET 4930
+ P + P+ + E+ E + E EE E + P +A ++ E+ ++
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 4931 D-------------QNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHP--EEH 4975
+ E++SP++ + E+ K+ + + + + + A+ P EE
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 4976 SEEQQQSVEEKDKEADEEGGE---------NGPADQGFQPQEEEEREDSDTEEQVPEALE 5026
++ EK K D + E PAD+ + + +E+ + E+ L
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL- 803
Query: 5027 RKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLAS 5086
KE A + + + + +P KE+ K + +AE ++ +
Sbjct: 804 -KEDAKAPEKEIPKKEEVK-------SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 5087 QKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDAD 5146
+K ++K K P E+ E ++ + ++ E+ + + + +
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEK-----KEPAVEKPKESKVEAKKEEA-EDKKKVPTPEKE 909
Query: 5147 AFEHIKQGSDAYDAQTYDVASKEQQQS-AKDSGKDQEEEEIEDTLMDTEEQEEFKAADVE 5205
A ++ DA + +VA KE + AK+ K E++E DT+E+ +
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE--------K 961
Query: 5206 QLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHK-----ETENEKPERSRE 5259
KPEE K T A D+ + ++E P+ +KA K + +++ PE++ E
Sbjct: 962 AKKPEE-KPKTEAKAKEDDKTL------SKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 49.7 bits (117), Expect = 8e-05
Identities = 62/319 (19%), Positives = 129/319 (40%), Gaps = 28/319 (8%)
Query: 4707 QEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKS---DSEGGDLDKHM 4763
+E+ K +KS +K E E ++ + + E+ + EK+ D + +
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKS--PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 4764 GDLNGEEADKLDERLWGDDDEE-EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSN 4822
+ ADK E+ EE + E+ + +E ++E + K + + S
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKE----IPKKEEVKSPVKE 826
Query: 4823 KDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLP 4882
++K Q+ K +E + ++ K E+ D + + + + E+ EP A++ P
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP-AVEKP 885
Query: 4883 DDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 4942
+ ++++ + + E+E P +++ K + E E + E D +++ P +P
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945
Query: 4943 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE-------EKDKEADEEGG 4995
E K E+ DT + A+ PEE + + ++ E E K E+
Sbjct: 946 E-----KKEAAPEKKDTKEEK-----AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 4996 ENGPADQGFQPQEEEERED 5014
++ DQ E+ ED
Sbjct: 996 KSSSTDQKDSKPPEKATED 1014
Score = 45.8 bits (107), Expect = 0.001
Identities = 60/304 (19%), Positives = 120/304 (39%), Gaps = 47/304 (15%)
Query: 4704 QKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHM 4763
+K + D + P++K+ K E A ++ F K EE + ++ D
Sbjct: 754 EKAKTLDVKSPEAKTPAKEE--ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811
Query: 4764 GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAK-DDNLDSGNSN 4822
++ +E K +E+E+ ++ K +E +EE + K ++ DS
Sbjct: 812 KEIPKKEEVK--------SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 4823 KDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEA---- 4878
K + K + +E+ E E K+ + +E + +++KVP PE
Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE-----------DKKKVPTPEKEAPA 912
Query: 4879 -LDLPDDLNLDSEDKNGGEDTDNEEGEEEN-PLEIKEKPEEAGHEAEERGETETDQNESQ 4936
+++ +D + + ++ D+ + +E + P E KE E EE+
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA---------- 962
Query: 4937 SPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGE 4996
++PEE P + KA+ + D P+ E+ S ++KD + E+ E
Sbjct: 963 --KKPEEKPKTEAKAKED-------DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Query: 4997 NGPA 5000
+ A
Sbjct: 1014 DKAA 1017
Score = 37.0 bits (84), Expect = 0.55
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 9/153 (5%)
Query: 4698 QVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGG 4757
+VE+ + EK KE SK + K E+ + K ++E +E+ K +E
Sbjct: 873 KVEEKKEPAVEKPKE---SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929
Query: 4758 DLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP--GMDEEDSELVAKDDN 4815
K D +E K E+ ++++ +EE+ K EE +ED + ++K+ +
Sbjct: 930 K--KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 4816 LDSGNSNKDKSQQDKKEEK--EEAEADDGGQGE 4846
+ S D+K+ K E+A D +G+
Sbjct: 988 KPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 80.5 bits (197), Expect = 4e-14
Identities = 83/406 (20%), Positives = 181/406 (44%), Gaps = 47/406 (11%)
Query: 4678 GGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDP--DSKSDIKGEDNAIEMSEDFDG 4735
G + E EG + E++ + Q+GQ +++E + + ++ ++ + E G
Sbjct: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---G 108
Query: 4736 KMHDGELEEQEEDDEKSDSEG------GDLDKHMGDLNGEEADKLDERLWGDDDEEEDEE 4789
++ + E + +E++ + + EG G + + G + +E ++ + E + E
Sbjct: 109 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 168
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNL--DSGNSNKDKSQQDKKEEKEEAEADDGGQGED 4847
+E E+ G + E++ ++ ++ + G + + Q ++EE+ + + + G+ E+
Sbjct: 169 QEGQVREQEGQ-VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEEN 4907
++ +Q ++ E +V +K E + +++ E + +EE
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEE----------QMRKQEEQMREQEEQMREQEEQ 277
Query: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
L+ KE+ E+ E+ GE E E QE + E+ E EE+M +Q+
Sbjct: 278 MLKQKEQTEQE----EQTGEQEEQMRE----QEEQMREQEEQMREQEEQMR----EQEEQ 325
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDT----EEQVPE 5023
+ E+ E+++Q E+K++ +E + G ++ Q QEE+ R+ + EEQ+ +
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEE-QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Query: 5024 ALE--RKEHASCG----QTGVENMQNTQAMELAGAAPEKEQGKEEH 5063
E RK+ G Q G + Q + E G E+ + +EEH
Sbjct: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Score = 75.5 bits (184), Expect = 1e-12
Identities = 64/341 (18%), Positives = 157/341 (46%), Gaps = 21/341 (6%)
Query: 4678 GGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDP--DSKSDIKGEDNAIEMSEDFDG 4735
G + E EG + E++ + Q+GQ +++E + + ++ ++ + E
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-QV 173
Query: 4736 KMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKT 4795
+ +G++ EQE + + + G+ + MG+ E+ + +E++ +++ ++EE+ K
Sbjct: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQE-EQMGEQEEQMQKQEEQMGEQEEQMRKQ 232
Query: 4796 EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDE 4855
EE M E++ ++ +++ + K + Q K+EE+ + + + E+++ +Q ++
Sbjct: 233 EEQ---MGEQEEQVQKQEEQVQ-----KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284
Query: 4856 RDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKP 4915
+ +E + +E++ E E + + +++ E + +EE E KE+
Sbjct: 285 TEQEEQTGE----QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 4916 EEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEH 4975
E + ++ E +Q E QE + E+ + EE+M + + + EE
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR-----KQEEQMRKQEEQ 395
Query: 4976 SEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSD 5016
EQ++ + E+ ++ E+ + G + + QEE E +
Sbjct: 396 MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 74.7 bits (182), Expect = 2e-12
Identities = 96/512 (18%), Positives = 197/512 (38%), Gaps = 91/512 (17%)
Query: 4710 DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
++E + ++++ E +E +E + ++H EL+ + E D+ + G + + G + +
Sbjct: 6 NEELKEKNAELQEELQLVE-TEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQ 64
Query: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQD 4829
E ++ + E + E+E E+ G ++E V + + + + Q+
Sbjct: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ--VREQEGQVREQEGQVREQEG 122
Query: 4830 KKEEKEEAEADDGGQ---GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLN 4886
+ E+E + GQ E ++ EQ + E +V G +V E E
Sbjct: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG---QVREQE--------- 170
Query: 4887 LDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET---DQNESQSPQEPEE 4943
G+ + E E +++E+ + G + + GE E +Q E QE +
Sbjct: 171 --------GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
Query: 4944 GPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQG 5003
G E+ + EE+M G ++ + + EEQ + EE+ +E +E+ E
Sbjct: 223 GEQEEQMRKQEEQM--GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Query: 5004 FQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEH 5063
+ Q E+E + + EEQ+ E E+ E + + E E++ GK+E
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQEEQMR---------EQEEQMREQEEQMREQEEQMGKQEE 331
Query: 5064 GSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRT 5123
Q+ QK Q +++K E MG+ E++ K+
Sbjct: 332 -------------------QMWEQKE-----QMWEQKEQMWKQEEQMGEQEEQMQKQE-- 365
Query: 5124 VDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEE 5183
E +++ + Q + +E+Q ++ +++
Sbjct: 366 -------------------------EQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Query: 5184 EEIEDTLMDTEEQEEFKAADVEQLKPEEIKSG 5215
E++ + EQEE EQ++ +E G
Sbjct: 401 EQMGEQKEQMREQEEQMGEQKEQMRKQEEHMG 432
Score = 74.3 bits (181), Expect = 3e-12
Identities = 84/419 (20%), Positives = 164/419 (39%), Gaps = 20/419 (4%)
Query: 4900 NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
N E +EE L EK E H E + + ETD+ + E + + EG+
Sbjct: 13 NAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQE 72
Query: 4960 GADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
G + + E EQ+ V E++ + E+ G+ + + QE + RE
Sbjct: 73 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 132
Query: 5020 QVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKE-QGKEEHGSGAADANQAEGHES 5078
+ + +E Q G Q Q E G E+E Q +E+ G + EG
Sbjct: 133 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG----QVREQEGQVR 188
Query: 5079 NFIAQLASQKHT--RKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQ 5136
Q+ Q+ + Q +++ E MG+ E++ K+ + Q +
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248
Query: 5137 QPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ 5196
Q Q Q E E + + + + K+++Q+ ++ ++EE++ + EQ
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
Query: 5197 EEFKAADVEQLKPEEIKSGTTAPLGFDE----MEVEIQTVKTEEDQDPRTDKAHKETE-- 5250
EE EQ++ +E + G +++ E + Q K EE + ++ K+ E
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQV 368
Query: 5251 --NEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEK 5307
E+ R +E + + + Q + E ++++ Q E + +E E+++
Sbjct: 369 RKQEEQMRKQEEQMRKQEEQMRKQEEQ-----MGEQKEQMGEQKEQMREQEEQMGEQKE 422
Score = 62.4 bits (150), Expect = 1e-08
Identities = 74/432 (17%), Positives = 175/432 (40%), Gaps = 24/432 (5%)
Query: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEEN 4907
++ E++ + +++E+ + ++ E + + LP + + ++ G+ + E E
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQE---GQVREQEGQVREQ 71
Query: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
+++E+ + + + E E E + +EG + + + E+ + +Q+G
Sbjct: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQ 130
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE-DSDTEEQVPEALE 5026
+ E EQ+ V E++ + E+ G+ + + QE + RE + EQ + E
Sbjct: 131 VREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 5027 RKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEH-GSGAADANQAEGHESNFIAQLA 5085
++ GQ G + Q + E G E+ Q +EE G + E Q+
Sbjct: 190 QE-----GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 5086 SQKHT--RKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVE 5143
Q+ ++ Q K++ + E M + E++ K+ + + + Q + + +
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 5144 DADAFEHIKQGSDAYDAQTYDVASKEQQQ--------SAKDSGKDQEEEEIEDTLMDTEE 5195
+ E +++ + Q + +E+Q K+ QEE+ E ++
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Query: 5196 QEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPE 5255
+E+ + + + K EE + E ++ Q + E ++ ++ +E E+ E
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ--EEQMGEQKE 422
Query: 5256 RSRESTIHTAHQ 5267
+ R+ H Q
Sbjct: 423 QMRKQEEHMGEQ 434
Score = 35.4 bits (80), Expect = 1.6
Identities = 27/147 (18%), Positives = 66/147 (44%), Gaps = 8/147 (5%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
E+ E + + E + E M++ +Q+G +E+ ++ + KE + +
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQM 354
Query: 4722 GEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLN---GEEADKLDERL 4778
GE ++ + + ++ +QEE K + + ++ MG+ GE+ +++ E+
Sbjct: 355 GEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ- 413
Query: 4779 WGDDDEEEDEEEEDNKTEETGPGMDEE 4805
+E+ E++E + +E G +E
Sbjct: 414 ----EEQMGEQKEQMRKQEEHMGEQKE 436
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 80.5 bits (197), Expect = 4e-14
Identities = 148/737 (20%), Positives = 294/737 (39%), Gaps = 88/737 (11%)
Query: 4692 QIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAI--EMSEDFDGKMHDGELEEQEEDD 4749
Q+ E+Q+ Q +E+++E + K + + + + E E D + E E E++
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 4750 EKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSEL 4809
K L ++ ++ ER W +EEE E+++ + ++ +E +
Sbjct: 472 RKQQ------------LKRDQEEERRER-WLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEA----DDGGQGEDKINEQIDERDYDENEVDP 4865
+ + + + QQ ++E++E E ++ + E + EQ +R+ +E
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK-EKPEEAGHEAEE 4924
+E+ + L + L+ K E+ + E EE +K E+PEE +
Sbjct: 579 LKREEER--RQQRLKREQEERLEQRLKR--EEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 4925 RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE 4984
+ E + ++ + Q +E +E + K E EEE ++ + + +E +EE+Q+
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 4985 EK------------DKEADEEGGE--NGPADQGFQ--PQEEEE---REDSDTEEQVPEAL 5025
E+ + EAD + + P Q Q QE+EE R +S+ + Q E
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 5026 ERKEHAS------CGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESN 5079
R++ Q E L+ P +EQ + + A + + E
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ-----LRAEERQQREQR 809
Query: 5080 FIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ 5139
F+ + +K R+ + + K Q E ER + + D E ++ Q
Sbjct: 810 FLPE-EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE--EEDGLQEDQERRRSQ 866
Query: 5140 AQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI--EDTLMDTEEQE 5197
Q D +++ Y + ++Q + +EEEE+ E+ +++
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 5198 EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETE----NEK 5253
E + + EQL+ EE L +E E + + E ++ R DK ++ E E+
Sbjct: 927 ERQYREEEQLQQEE------EQLLREERE---KRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 5254 PER----SRESTIHTAHQFLMDTIFQPFLKDVNE--LRQELERQLEMWQPRESGNPEEEK 5307
PE+ RE + + + L++ E RQE ERQ ++ ++ EEE+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEE--EQLLREEREKRRRQEWERQ---YRKKDELQQEEEQ 1032
Query: 5308 VAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKVIPYIASQFR 5367
+ E + + R EEL+ + +L G+ R +R + + +
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQ-----QEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 5368 KDKIWLRRTKPSKRQYQ 5384
+++ L R +P KR+ Q
Sbjct: 1088 QEEEQLLREEPEKRRRQ 1104
Score = 78.6 bits (192), Expect = 2e-13
Identities = 122/656 (18%), Positives = 251/656 (38%), Gaps = 111/656 (16%)
Query: 4708 EKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQ--------EEDDEKSDSEGGDL 4759
E+ + D K + + E F+ + D +LEE+ ++ E+ +EG +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPR--DRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 4760 DKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE-----DSELVAKDD 4814
+ L + + DE LW E ++ EE + E+ E D E + + +
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 4815 NLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVP 4874
L+ +++ QQ ++E +D++ ++ +E+++ + E +EK+
Sbjct: 215 LLELRRKGREEKQQQRRER------------QDRVFQEEEEKEWRKRET-VLRKEEEKLQ 261
Query: 4875 EPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNE 4934
E E E EEE L E+ E EE + + + E
Sbjct: 262 EEEP------------------QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 4935 SQ--SPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADE 4992
Q QE E ++++ E +E + + ++ + EE E+Q + +E+++
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR--- 360
Query: 4993 EGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGA 5052
+Q + ++EEER + + + L R++ Q ++ Q +
Sbjct: 361 --------EQQLRREQEEERREQQLRRE--QQLRREQQLRREQ----QLRREQQLRREQQ 406
Query: 5053 APEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGD 5112
++Q + E Q E + ++H +K+ Q + +R +
Sbjct: 407 LRREQQLRRE---------QQLRREQQLRREQEEERHEQKHEQ-------ERREQRLKRE 450
Query: 5113 HNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQ 5172
ER R +T+ H ++ QQ + E+ +K + +EQQ+
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE---------ERREQQE 501
Query: 5173 SAKDSGKDQEEEEIEDTLMDTEEQEEF--KAADVEQLKPEEIKSGTTAPLGFDE--MEVE 5228
+ + ++EE E L EE+E + +QL+ E+ + +E +E E
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 5229 IQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQEL 5288
+ + + +Q+ R D+ K E + +R + Q L ++V L QE
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-------REEVERLEQEE 614
Query: 5289 ERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLK 5344
R+ Q + PEEE+ + L+ + +R ++LR + + +LK
Sbjct: 615 RRE----QRLKREEPEEER------RQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Score = 76.3 bits (186), Expect = 8e-13
Identities = 114/622 (18%), Positives = 251/622 (40%), Gaps = 75/622 (12%)
Query: 4697 EQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEG 4756
E+ + FQ +E++KE ++ ++ E+ ++ E EL+E+EE K + +
Sbjct: 232 ERQDRVFQ--EEEEKEWRKRETVLRKEEEKLQEEEP----QRQRELQEEEEQLRKLERQ- 284
Query: 4757 GDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNL 4816
+L + + ++ E+ EEE E+++ + E+ +E+
Sbjct: 285 -ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER--------- 334
Query: 4817 DSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEP 4876
+ QQ ++E++E E + E++ EQ R+ +E + ++++
Sbjct: 335 --------REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 4877 EALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQ 4936
+ L L + + + ++ E L + ++ E + R E E +++E +
Sbjct: 387 QQLRREQQLRREQQLRR------EQQLRREQQL---RREQQLRREQQLRREQEEERHEQK 437
Query: 4937 SPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGE 4996
QE E + K E EE D +++ E H +E+++ ++D+E +
Sbjct: 438 HEQERRE---QRLKREQEERRDWLKREEE------TERHEQERRKQQLKRDQEEERR--- 485
Query: 4997 NGPADQGFQPQEEEEREDSDTEEQV--PEALERKEHASCGQTGVENMQNTQAMELAGAAP 5054
++ + +EEE RE + EQ E ER+E Q E +Q E
Sbjct: 486 ----ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE-----Q 536
Query: 5055 EKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHN 5114
+ + +EE + + E Q ++ + Q KR+ + +R +
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE-ERRQQRLKREQE 595
Query: 5115 ERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSA 5174
ER+ +RL+ + + ++ +Q + E + S+ + + +EQQ+
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 5175 KDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKS--GTTAPLGFDEMEVEIQTV 5232
+ K +EEEE + + E +EE + ++ + + E+ + + P ++E E
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 5233 KTEEDQDPRTDKA-HKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQ 5291
+++ PR + + E E+ R RES + + + + +QE E++
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE-----------ERAHRQQQEEEQR 764
Query: 5292 LE---MWQPRESGNPEEEKVAA 5310
+ WQ E ++++A
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSA 786
Score = 76.3 bits (186), Expect = 8e-13
Identities = 127/662 (19%), Positives = 267/662 (40%), Gaps = 62/662 (9%)
Query: 4687 KDVSDQIGNEEQVEDTFQKGQEKDKEDPDSK--SDIKGEDNAIEMSEDFDGKMHDGELEE 4744
+++ Q EE+V+ Q+ ++ +E+P+ + +++ + E + + ++ E E+
Sbjct: 1134 QELERQYREEEEVQ---QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Query: 4745 QEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDN---KTEETGPG 4801
+ ++ E+ E +L + + D+ + W + E+E+ ++ K E
Sbjct: 1191 RRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 4802 MDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDEN 4861
EDS+L + D + ++ ++D+++E+ + D E+ EQ++ + E
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE---EQLEREEQKEA 1307
Query: 4862 EVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHE 4921
+ +EK L + E+K ++TD + EEE L+ +E+ E
Sbjct: 1308 KRRDRKSQEEK----------QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
Query: 4922 AEERGETETDQNESQSPQEPEEGP----SEDDKAEGEEEMDTGADDQDGDAAQHPEE--H 4975
+ + E +++ Q + EE E ++ +EE +++ Q +
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 4976 SEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERK--EHASC 5033
EEQQ S +E+D++ EE + ++E ER+ + E+Q+ + RK E
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQ--------VRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 5034 GQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADAN-QAEGHESNFIA---QLASQKH 5089
Q E + Q + E++ ++E + +++ E F+ QL Q+
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR 1529
Query: 5090 TRKNTQSFKRKPGQADNERSMGDHN-----------ERVHKRLRTVDTDSH---AEQGPA 5135
RK Q ++ Q ++ D + ER ++L + D EQ
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 5136 QQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEE 5195
+Q Q + D + +Q Q D +E +Q ++ + Q + D EE
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649
Query: 5196 QEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPE 5255
+ + +QL+ + + F E E +Q + ++ + D+ +E E +
Sbjct: 1650 PQLRRQEREQQLRHDRDRK-------FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 5256 RSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQS 5315
+ RE Q L + ++ +LRQE E++ Q R EEE++ E +
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 5316 YL 5317
L
Sbjct: 1763 QL 1764
Score = 72.4 bits (176), Expect = 1e-11
Identities = 139/699 (19%), Positives = 261/699 (37%), Gaps = 111/699 (15%)
Query: 4696 EEQVEDTFQKGQEKDKEDP--DSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEED----- 4748
EE+ E ++ +E++KE + + ++ + A ++ E+ DG D E +E
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 4749 ----------------------DEKSDSEGGDLDKHMGDLNGEEADKL----DERLWGDD 4782
E+ E L + +L EE +K ER + ++
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 4783 DEEEDEEEEDNKTEETGPGMDE------EDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE 4836
++ + EEE+ + E E +D +L K++ L K + Q+ +K+ +EE
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 4837 AEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL--DLPDDLNLDSEDKNG 4894
E + E + E+ ++R E E Y E E E L + + L ++
Sbjct: 994 EELQQ--EEEQLLREEREKRRRQEWERQ-YRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 4895 GEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQ----------------SP 4938
E+ + ++ EE+ E +E E + R E E Q E Q
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 4939 QEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENG 4998
+E EE E+++ EE + + + E EE+Q EE +K +E
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 4999 PADQGFQPQEEE-----------EREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAM 5047
++ Q +EE+ ERE EE+ + +RK+ Q
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQ---------RYRDEDQRS 1221
Query: 5048 ELAGA-APEKEQGKEEHGSGAADANQAEGHESNFIAQLA-SQKHTRKNTQSFKRKPGQAD 5105
+L PEKE + + +G E+ QL SQ R++ Q + G+
Sbjct: 1222 DLKWQWEPEKENAVRD------NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ- 1274
Query: 5106 NERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDV 5165
+R +R R D H P ++ + E +A + D + +
Sbjct: 1275 ------QERDREQERRRWQQRDRHF---PEEEQLEREEQKEA-----KRRDRKSQEEKQL 1320
Query: 5166 ASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEM 5225
+E+++ + D++ E E L + EEQ + + + EE++ +E
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 5226 E----VEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDV 5281
+ E + +E+Q R + ++ ++ + RE + Q D F+ + V
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ-ERDRKFREEEQQV 1439
Query: 5282 NELRQE---LERQLEMWQPRESGNPEEEKVAAEMWQSYL 5317
+E LE + ++ Q R EEE++ E + L
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Score = 63.5 bits (153), Expect = 5e-09
Identities = 75/367 (20%), Positives = 154/367 (41%), Gaps = 45/367 (12%)
Query: 4959 TGADDQ-----DGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE 5013
TG D++ DG + + EE Q+ E +D++ +EE P + Q ++E+ERE
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE-----PGQRRRQKRQEQERE 147
Query: 5014 DSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQA 5073
++ EEQ E ER E + E + Q + Q +EE +
Sbjct: 148 LAEGEEQ-SEKQERLEQRDRQRRDEELWRQRQ----------EWQEREERRAEEEQLQSC 196
Query: 5074 EGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHK-------RLRTVDT 5126
+GHE+ + ++ R+ R+ G+ + ++ + +RV + R R
Sbjct: 197 KGHETE---EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 5127 DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
E+ ++PQ Q E + E +++ + ++QQ+ ++ +++EE
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE- 312
Query: 5187 EDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAH 5246
E +E+ + +Q + E+ + L ++ E Q ++ E++++ R +
Sbjct: 313 -------ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 5247 KETENEKPERS--RESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPE 5304
+E E E+ E+ RE + Q + L+ +LR+E + + E RE
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRR----EQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 5305 EEKVAAE 5311
E+++ E
Sbjct: 422 EQQLRRE 428
Score = 57.8 bits (138), Expect = 3e-07
Identities = 103/576 (17%), Positives = 227/576 (39%), Gaps = 62/576 (10%)
Query: 4692 QIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEE---- 4747
Q+ EE+ E ++ QE D++ + + ++ + ++ D K + EL QE+
Sbjct: 1319 QLLREEREEK--RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKF 1376
Query: 4748 -DDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEED 4806
++E+ K + + + +++L D D + EEE+ +E EE+
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 4807 SEL---------VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQG------EDKINE 4851
++ + ++ L K + ++ +E+EE + + E ++
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Query: 4852 QIDERDYDENEVDPYHGNQEKVPEPEALD--------LPDDLNLDSEDKNGG--EDTDNE 4901
Q +R + E E+ ++ + E + L L ++ L +++ +D D +
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 4902 EGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDD----KAEGEEEM 4957
EEE +++++ EE +ER + + QE E ED+ + EG++++
Sbjct: 1557 FREEE---QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 4958 DTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGE----------NGPADQGFQPQ 5007
D + + Q +E EEQQ +E+D++ EE + D+ F+ +
Sbjct: 1614 RQERDRKFREDEQLLQER-EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 5008 EE--EEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGS 5065
E+ +E E+ Q + R+E + E + +L E++ +EE
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 5066 GAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVD 5125
+ Q E Q + Q +R+ ER ++LR+ +
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Query: 5126 TDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQ--------QQSAKDS 5177
+D + +Q + + E+ + G ++ + + +EQ Q A++
Sbjct: 1793 SDRKFRE--EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 5178 GKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIK 5213
QE+ E+ + EE+++ + +L+ E I+
Sbjct: 1851 FATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Score = 55.8 bits (133), Expect = 1e-06
Identities = 62/383 (16%), Positives = 152/383 (39%), Gaps = 31/383 (8%)
Query: 4707 QEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDL 4766
Q++ ++ + ++ ++ + +D D K + E QE ++++ + D + +
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 4767 NGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKS 4826
++ ER + +D+++ +E + + ED +L+ + + +D+
Sbjct: 1587 KVRRQEQ--ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 4827 --------QQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKV----- 4873
++ ++E++ + D + E+++ ++ +E+ E D +E+
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 4874 PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQ- 4932
E + L L ++ E+ + E+ L +E+ + E + R E E Q
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764
Query: 4933 ----------NESQSPQEPEE----GPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHS-E 4977
E Q QE EE D K EE++ ++Q Q ++ E
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 4978 EQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTG 5037
E+Q +EE+++ +E A++ F QE+ RE+ + ++ + ++ +
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEH 1884
Query: 5038 VENMQNTQAMELAGAAPEKEQGK 5060
+ Q + + ++GK
Sbjct: 1885 IRRQQKEEQRHRQVGEIKSQEGK 1907
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 79.3 bits (194), Expect = 1e-13
Identities = 117/607 (19%), Positives = 240/607 (39%), Gaps = 86/607 (14%)
Query: 4684 EGMKDVSDQIGNEEQVEDTFQ-------KGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGK 4736
+G+ D++++ ++Q ++T + KG E+ K+ D K + + E S D K
Sbjct: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 980
Query: 4737 MHDGE----LEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD---ERLWGDDDEEEDEE 4789
+ + E + + + ++G K + D ++ D+L E+ G D +
Sbjct: 981 LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDS--CDS 1038
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKI 4849
ED K++ G +++ +L+ K S+ D + KE DG DK
Sbjct: 1039 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE--------DGCNSSDKR 1090
Query: 4850 NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPL 4909
++I+ R E +L N E ++G +D EE E+N
Sbjct: 1091 LKRIELR--------------------ERRNLSSKRNT-KEIQSGSSSSDAEESSEDN-- 1127
Query: 4910 EIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAA 4969
K+K + + + E +N ++ + + + + + +D +D D
Sbjct: 1128 --KKKKQRTSSKKKAVIVKEKKRNSLRTSTK---------RKQADITSSSSSDIEDDDQN 1176
Query: 4970 QHPEEHSEEQQ-QSVEEKDKEADEEGGENGPADQGFQPQE----EEEREDSDTEEQVPEA 5024
E S+EQ+ + V E + G D+ +++ +D+D E ++ +
Sbjct: 1177 SIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKK 1236
Query: 5025 L---ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE---HGSGAADANQAEGHES 5078
+ E K + S + G + + + + G E+ G EE + +D++ E +
Sbjct: 1237 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKP 1296
Query: 5079 NFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTD----------- 5127
+ +L K T + +S + K + + + N R + D+D
Sbjct: 1297 RYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVS 1356
Query: 5128 -SHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
S EQ P + + E + KQ + + +S E + ++++ +++EEEE
Sbjct: 1357 ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE 1416
Query: 5187 EDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAH 5246
E + EE+EE + + + P + + L D++ E Q +E+++ R A
Sbjct: 1417 E----EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA-LKEEEERRKRIAE 1471
Query: 5247 KETENEK 5253
+E E EK
Sbjct: 1472 REREREK 1478
Score = 63.5 bits (153), Expect = 5e-09
Identities = 59/278 (21%), Positives = 117/278 (42%), Gaps = 9/278 (3%)
Query: 4746 EEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE 4805
++DD+ +D E K + L +A+ + DDE E+ ++ K E PG DEE
Sbjct: 1221 DDDDDDNDPENRIAKKML--LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPG-DEE 1277
Query: 4806 DSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDP 4865
V + + DS S K + + K DG GE+K + + ++
Sbjct: 1278 AKNQVNSESDSDSEESKKPRYRHRLLRHK--LTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE-EENPLEIKEKPEEAGHEAEE 4924
+ + + + ++++ +SED+ ++ E EEN K+K + + +E
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVS-ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1394
Query: 4925 RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE 4984
+E N + +E EE E+++ E EEE + G + + ++ + E
Sbjct: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTE 1454
Query: 4985 EKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVP 5022
++ +EE A++ + + E+ RE + E+ P
Sbjct: 1455 TQNALKEEEERRKRIAER--EREREKLREVIEIEDASP 1490
Score = 55.8 bits (133), Expect = 1e-06
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 27/173 (15%)
Query: 4692 QIGNEEQVEDTFQKG-------QEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEE 4744
++ +E+ + FQ+ + +D++ P ++S K E + S K +++E
Sbjct: 1335 KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1394
Query: 4745 QEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDE 4804
+ KS+SE EE +K +E +++EEE+EEEED + PG
Sbjct: 1395 DSSSENKSNSEE------------EEEEKEEEE---EEEEEEEEEEEDENDDSKSPGKGR 1439
Query: 4805 EDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERD 4857
+ + KDD L + N K ++++++ E E + +K+ E I+ D
Sbjct: 1440 KKIRKILKDDKLRTETQNALKEEEERRKRIAERERE-----REKLREVIEIED 1487
Score = 44.3 bits (103), Expect = 0.003
Identities = 91/577 (15%), Positives = 200/577 (34%), Gaps = 59/577 (10%)
Query: 4733 FDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEED 4792
+D K G+ +++ + KS + G D D G +R + D E E
Sbjct: 727 YDLKTQAGK-DDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEK 785
Query: 4793 NKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQ 4852
+ G + + + DS K + + + + G +D
Sbjct: 786 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDA---- 841
Query: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
ER + G +K + ++L D L + + D G+E++ ++
Sbjct: 842 --ERKQERETFSSAEGTVDK--DTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLE 897
Query: 4913 EKPEEAGHEAEERGETET---------DQNESQSPQEPEEGPSEDDKAEGEEEMDTGADD 4963
+ E + +T+T D E ++ + SEDDK + ++ +
Sbjct: 898 VRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKP 957
Query: 4964 QDGDAAQHPEEHSEEQQQSVEEKDKEADE--------EGGENGPADQGFQPQEEEEREDS 5015
D E E EK E +E + +NG D G + ++ + S
Sbjct: 958 SDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTD-GEKKSKKIRDKTS 1016
Query: 5016 DTEEQVPEALERK--EHASCGQTGVENMQN------TQAMELAGAAPEKEQ--------- 5058
++++ + E+ + SC + + +N + +L G + K Q
Sbjct: 1017 KKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEK 1076
Query: 5059 -GKEEHGSGAAD-----------ANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
+E G ++D N + + I +S ++++ K+K + +
Sbjct: 1077 YSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSS 1136
Query: 5107 ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVA 5166
++ E+ LRT A+ + + +D ++ T ++
Sbjct: 1137 KKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV 1196
Query: 5167 SKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAP---LGFD 5223
+ SG + + + T+ D ++ + + +++ EEIK+ ++ D
Sbjct: 1197 LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD 1256
Query: 5224 EMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRES 5260
E E + + +++P ++A + +E S ES
Sbjct: 1257 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEES 1293
Score = 43.9 bits (102), Expect = 0.005
Identities = 103/568 (18%), Positives = 202/568 (35%), Gaps = 99/568 (17%)
Query: 4789 EEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKK-EEKEEAEADDGGQGED 4847
E++D E + DSE + ++ + +NK + KK + KEE + + ED
Sbjct: 415 EKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSED 474
Query: 4848 ----------KINEQIDERDYDENEVD---PYHGNQEKVPEPEALDLPDDLNLDSEDKNG 4894
+ E I E EV + G+ E E LN+ S+D G
Sbjct: 475 LDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRG 534
Query: 4895 G------EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEP-----EE 4943
G E + P+ + P + E + + ++ +P+ +E
Sbjct: 535 GIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE 594
Query: 4944 GPSEDDKAEGE-----EEMD---------------TGADDQDGDAAQHPEEHSEEQQQ-- 4981
+ E E EE D T + ++ + E +E+Q+
Sbjct: 595 NSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLS 654
Query: 4982 -SVEEKDKEADEEGGENGP----ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQT 5036
V +KDK + + P + Q + ++ DSD + + + R H+S T
Sbjct: 655 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDT 714
Query: 5037 GVENMQNTQ--AMELAGAAPEKEQGKEEHGSGAADAN-------------------QAEG 5075
+ + +L A + ++GK + S + ++ Q +
Sbjct: 715 DINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQS 774
Query: 5076 HESNF----------IAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVD 5125
SN+ ++++ + + T+K + K D + S + + HK L+T
Sbjct: 775 ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKT-S 833
Query: 5126 TDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQ-EEE 5184
+ ++ +Q + A+ D + D K+QQ SA G D+ +
Sbjct: 834 QEGSSDDAERKQERETFSSAEG----TVDKDTTIMELRDRLPKKQQASASTDGVDKLSGK 889
Query: 5185 EIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEI----QTVKTEEDQDP 5240
E T ++ + E K E+ K + K+ G ++ + Q+ +T ED
Sbjct: 890 EQSFTSLEVRKVAETK----EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKK 945
Query: 5241 RTDKAHKETENEKPERSRESTIHTAHQF 5268
++ K + E +KP ++ I Q+
Sbjct: 946 QSKKGTE--EKKKPSDFKKKVIKMEQQY 971
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 79.3 bits (194), Expect = 1e-13
Identities = 117/607 (19%), Positives = 240/607 (39%), Gaps = 86/607 (14%)
Query: 4684 EGMKDVSDQIGNEEQVEDTFQ-------KGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGK 4736
+G+ D++++ ++Q ++T + KG E+ K+ D K + + E S D K
Sbjct: 959 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 1018
Query: 4737 MHDGE----LEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD---ERLWGDDDEEEDEE 4789
+ + E + + + ++G K + D ++ D+L E+ G D +
Sbjct: 1019 LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDS--CDS 1076
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKI 4849
ED K++ G +++ +L+ K S+ D + KE DG DK
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE--------DGCNSSDKR 1128
Query: 4850 NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPL 4909
++I+ R E +L N E ++G +D EE E+N
Sbjct: 1129 LKRIELR--------------------ERRNLSSKRNT-KEIQSGSSSSDAEESSEDN-- 1165
Query: 4910 EIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAA 4969
K+K + + + E +N ++ + + + + + +D +D D
Sbjct: 1166 --KKKKQRTSSKKKAVIVKEKKRNSLRTSTK---------RKQADITSSSSSDIEDDDQN 1214
Query: 4970 QHPEEHSEEQQ-QSVEEKDKEADEEGGENGPADQGFQPQE----EEEREDSDTEEQVPEA 5024
E S+EQ+ + V E + G D+ +++ +D+D E ++ +
Sbjct: 1215 SIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKK 1274
Query: 5025 L---ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE---HGSGAADANQAEGHES 5078
+ E K + S + G + + + + G E+ G EE + +D++ E +
Sbjct: 1275 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKP 1334
Query: 5079 NFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTD----------- 5127
+ +L K T + +S + K + + + N R + D+D
Sbjct: 1335 RYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVS 1394
Query: 5128 -SHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
S EQ P + + E + KQ + + +S E + ++++ +++EEEE
Sbjct: 1395 ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE 1454
Query: 5187 EDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAH 5246
E + EE+EE + + + P + + L D++ E Q +E+++ R A
Sbjct: 1455 E----EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA-LKEEEERRKRIAE 1509
Query: 5247 KETENEK 5253
+E E EK
Sbjct: 1510 REREREK 1516
Score = 63.5 bits (153), Expect = 5e-09
Identities = 59/278 (21%), Positives = 117/278 (42%), Gaps = 9/278 (3%)
Query: 4746 EEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE 4805
++DD+ +D E K + L +A+ + DDE E+ ++ K E PG DEE
Sbjct: 1259 DDDDDDNDPENRIAKKML--LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPG-DEE 1315
Query: 4806 DSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDP 4865
V + + DS S K + + K DG GE+K + + ++
Sbjct: 1316 AKNQVNSESDSDSEESKKPRYRHRLLRHK--LTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 4866 YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE-EENPLEIKEKPEEAGHEAEE 4924
+ + + + ++++ +SED+ ++ E EEN K+K + + +E
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVS-ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1432
Query: 4925 RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVE 4984
+E N + +E EE E+++ E EEE + G + + ++ + E
Sbjct: 1433 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTE 1492
Query: 4985 EKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVP 5022
++ +EE A++ + + E+ RE + E+ P
Sbjct: 1493 TQNALKEEEERRKRIAER--EREREKLREVIEIEDASP 1528
Score = 55.8 bits (133), Expect = 1e-06
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 27/173 (15%)
Query: 4692 QIGNEEQVEDTFQKG-------QEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEE 4744
++ +E+ + FQ+ + +D++ P ++S K E + S K +++E
Sbjct: 1373 KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQE 1432
Query: 4745 QEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDE 4804
+ KS+SE EE +K +E +++EEE+EEEED + PG
Sbjct: 1433 DSSSENKSNSEE------------EEEEKEEEE---EEEEEEEEEEEDENDDSKSPGKGR 1477
Query: 4805 EDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERD 4857
+ + KDD L + N K ++++++ E E + +K+ E I+ D
Sbjct: 1478 KKIRKILKDDKLRTETQNALKEEEERRKRIAERERE-----REKLREVIEIED 1525
Score = 44.3 bits (103), Expect = 0.003
Identities = 91/577 (15%), Positives = 200/577 (34%), Gaps = 59/577 (10%)
Query: 4733 FDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEED 4792
+D K G+ +++ + KS + G D D G +R + D E E
Sbjct: 765 YDLKTQAGK-DDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEK 823
Query: 4793 NKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQ 4852
+ G + + + DS K + + + + G +D
Sbjct: 824 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDA---- 879
Query: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
ER + G +K + ++L D L + + D G+E++ ++
Sbjct: 880 --ERKQERETFSSAEGTVDK--DTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLE 935
Query: 4913 EKPEEAGHEAEERGETET---------DQNESQSPQEPEEGPSEDDKAEGEEEMDTGADD 4963
+ E + +T+T D E ++ + SEDDK + ++ +
Sbjct: 936 VRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKP 995
Query: 4964 QDGDAAQHPEEHSEEQQQSVEEKDKEADE--------EGGENGPADQGFQPQEEEEREDS 5015
D E E EK E +E + +NG D G + ++ + S
Sbjct: 996 SDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTD-GEKKSKKIRDKTS 1054
Query: 5016 DTEEQVPEALERK--EHASCGQTGVENMQN------TQAMELAGAAPEKEQ--------- 5058
++++ + E+ + SC + + +N + +L G + K Q
Sbjct: 1055 KKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEK 1114
Query: 5059 -GKEEHGSGAAD-----------ANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
+E G ++D N + + I +S ++++ K+K + +
Sbjct: 1115 YSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSS 1174
Query: 5107 ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVA 5166
++ E+ LRT A+ + + +D ++ T ++
Sbjct: 1175 KKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV 1234
Query: 5167 SKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAP---LGFD 5223
+ SG + + + T+ D ++ + + +++ EEIK+ ++ D
Sbjct: 1235 LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD 1294
Query: 5224 EMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRES 5260
E E + + +++P ++A + +E S ES
Sbjct: 1295 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEES 1331
Score = 43.9 bits (102), Expect = 0.005
Identities = 103/568 (18%), Positives = 202/568 (35%), Gaps = 99/568 (17%)
Query: 4789 EEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKK-EEKEEAEADDGGQGED 4847
E++D E + DSE + ++ + +NK + KK + KEE + + ED
Sbjct: 453 EKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSED 512
Query: 4848 ----------KINEQIDERDYDENEVD---PYHGNQEKVPEPEALDLPDDLNLDSEDKNG 4894
+ E I E EV + G+ E E LN+ S+D G
Sbjct: 513 LDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRG 572
Query: 4895 G------EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEP-----EE 4943
G E + P+ + P + E + + ++ +P+ +E
Sbjct: 573 GIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE 632
Query: 4944 GPSEDDKAEGE-----EEMD---------------TGADDQDGDAAQHPEEHSEEQQQ-- 4981
+ E E EE D T + ++ + E +E+Q+
Sbjct: 633 NSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLS 692
Query: 4982 -SVEEKDKEADEEGGENGP----ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQT 5036
V +KDK + + P + Q + ++ DSD + + + R H+S T
Sbjct: 693 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDT 752
Query: 5037 GVENMQNTQ--AMELAGAAPEKEQGKEEHGSGAADAN-------------------QAEG 5075
+ + +L A + ++GK + S + ++ Q +
Sbjct: 753 DINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQS 812
Query: 5076 HESNF----------IAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVD 5125
SN+ ++++ + + T+K + K D + S + + HK L+T
Sbjct: 813 ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKT-S 871
Query: 5126 TDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQ-EEE 5184
+ ++ +Q + A+ D + D K+QQ SA G D+ +
Sbjct: 872 QEGSSDDAERKQERETFSSAEG----TVDKDTTIMELRDRLPKKQQASASTDGVDKLSGK 927
Query: 5185 EIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEI----QTVKTEEDQDP 5240
E T ++ + E K E+ K + K+ G ++ + Q+ +T ED
Sbjct: 928 EQSFTSLEVRKVAETK----EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKK 983
Query: 5241 RTDKAHKETENEKPERSRESTIHTAHQF 5268
++ K + E +KP ++ I Q+
Sbjct: 984 QSKKGTE--EKKKPSDFKKKVIKMEQQY 1009
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 79.0 bits (193), Expect = 1e-13
Identities = 90/356 (25%), Positives = 153/356 (42%), Gaps = 61/356 (17%)
Query: 4683 GEGMKDVSDQIGNEEQVEDTFQKG-QEKDKEDPDSKSDIKGEDNAIEMSED--FDGKMHD 4739
GE + S+ E E ++G EK+ E+ K +G + E E G D
Sbjct: 438 GEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEED 497
Query: 4740 GELEEQEEDDEKSDSEGGDLDKHM-GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEET 4798
+E ++ K+D E L K DLN E +++ ++D+ E E +ED +++
Sbjct: 498 SPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQS 557
Query: 4799 GPGMDEEDSELVAKDDNLDSGNSNKDKSQQ--DKKEEKEEAE----ADDGGQGEDKINEQ 4852
G + E E + D LD S K+ + DK+ E+ ++E DDG E ++E+
Sbjct: 558 EDGSEREFEENGLEKD-LDEEGSEKELHENVLDKELEENDSENSEFEDDGS--EKVLDEE 614
Query: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT-----DNEEGEEEN 4907
ER++DE DS++K EDT D+E E+E+
Sbjct: 615 GSEREFDE---------------------------DSDEKEEEEDTYEKVFDDESDEKED 647
Query: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
+E +E G EA ++ E D +E + ++ ED+ A+G+E D AD++ +
Sbjct: 648 ----EEYADEKGLEAADKKAEEGDADEKLFEESDDK---EDEDADGKEVED--ADEKLFE 698
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGG-------ENGPADQGFQPQEEEEREDSD 5016
E+ +E++ S E+ ++DE G E GP G + +D D
Sbjct: 699 DDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDD 754
Score = 67.8 bits (164), Expect = 3e-10
Identities = 86/352 (24%), Positives = 155/352 (44%), Gaps = 59/352 (16%)
Query: 4711 KEDPDSKSDIKGEDNAIEMSED-FDGKMHDGE----LEEQEEDDEKS---DSEGGDLDKH 4762
+ D S S+ G A SE KM+ E + +E DEK +GG+ ++
Sbjct: 384 RSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEG 443
Query: 4763 MGDLNGEEADKLDERLWGDDDEEEDE---------------EEEDNK---TEETGPGMDE 4804
+ N +E+ E G ++E +E EE N +EE P +
Sbjct: 444 ASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSP--KK 501
Query: 4805 EDSELVAKDDNLDSGNSNKDKSQQDKKEEKE-----EAEADDGGQGED-----KINEQID 4854
E + K+D ++G + + + +K+ E+E E+E DD + D K +E
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 4855 ERDYDENEVD---PYHGNQEKVPE---PEALDLPDDLNLDSEDKNGGEDTDNEEGEEENP 4908
ER+++EN ++ G+++++ E + L+ D N + ED +G E +EEG E
Sbjct: 562 EREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFED-DGSEKVLDEEGSE--- 617
Query: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDA 4968
+E E++ + EE E ++ +E EE E +G E D A++ D D
Sbjct: 618 ---REFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADE----KGLEAADKKAEEGDADE 670
Query: 4969 AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE----DSD 5016
E +E + + ++ ++ADE+ E+ +++ +EE+ E DSD
Sbjct: 671 KLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSD 722
Score = 66.2 bits (160), Expect = 8e-10
Identities = 94/444 (21%), Positives = 169/444 (38%), Gaps = 54/444 (12%)
Query: 4715 DSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDS------EGGDLDKHMGDLNG 4768
D +D + E+ + E E G E +SDS G +H +
Sbjct: 348 DGTTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPS 407
Query: 4769 EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ 4828
E G EE +E++ KTE+ G + E A ++N + K+ +
Sbjct: 408 TSKMNAQETATGMAFEEPIDEKKFEKTEDGG------EFEEGASENNAKESSPEKEAEEG 461
Query: 4829 DKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALD--LPDDLN 4886
++E EE G +G E E +P G++E P+ E+ L +D
Sbjct: 462 CPEKESEEGCPKRGFEGSCSQKES--------EEGNPVRGSEEDSPKKESKKKTLKNDCE 513
Query: 4887 LDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPS 4946
+ K +D + E EE P + E+E D +E +S ++ E S
Sbjct: 514 ENGLAKESEDDLNKESEEEVGPTK----------------ESEEDDSEKESDEDCSEKQS 557
Query: 4947 EDDKAEGEEEMDTGAD-DQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQ 5005
ED EE D D++G + E +++ + + ++ E +++G E ++G
Sbjct: 558 EDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEG-- 615
Query: 5006 PQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE--H 5063
E E EDSD +E+ + E+ + E + + +E A E+ E+
Sbjct: 616 -SEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Query: 5064 GSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQAD-NERSMGDHNERVHKRLR 5122
S + A+G E + A +K + + K + D +E+ D +ER
Sbjct: 675 ESDDKEDEDADGKE----VEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDER-----G 725
Query: 5123 TVDTDSHAEQGPAQQPQAQVEDAD 5146
T+ E+GP + + +D
Sbjct: 726 TLGGFGSVEEGPLSTGSSFILSSD 749
Score = 60.5 bits (145), Expect = 5e-08
Identities = 63/282 (22%), Positives = 121/282 (42%), Gaps = 10/282 (3%)
Query: 4667 EGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNA 4726
EG+ + E G G + + D + G K+ ED +K +
Sbjct: 477 EGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPT 536
Query: 4727 IEMSEDFDGKMHDGEL-EEQEEDDEKSDSEGGDLDKHMGDLNGEEADK-LDERLWGDDDE 4784
E ED K D + E+Q ED + + E L+K DL+ E ++K L E + + E
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEK---DLDEEGSEKELHENVLDKELE 593
Query: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ---DKKEEKEEAEADD 4841
E D E + + + + +DEE SE +D+ D +D ++ D+ +EKE+ E D
Sbjct: 594 ENDSENSEFEDDGSEKVLDEEGSEREFDEDS-DEKEEEEDTYEKVFDDESDEKEDEEYAD 652
Query: 4842 GGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE 4901
+G + +++ +E D DE + +++ + + ++ D+ + +D N + E
Sbjct: 653 E-KGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711
Query: 4902 EGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEE 4943
+ E+ + E+ G + E G T + S + ++
Sbjct: 712 DSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDD 753
Score = 56.2 bits (134), Expect = 9e-07
Identities = 56/252 (22%), Positives = 117/252 (46%), Gaps = 41/252 (16%)
Query: 4652 KGFCLPKEFMEDSAGEGATEF------------HDYEGGGIG---EGEGMKDVSDQIG-N 4695
+G C KE E + G+ E +D E G+ E + K+ +++G
Sbjct: 477 EGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPT 536
Query: 4696 EEQVEDTFQKGQEKDKEDPDSK--SDIKGEDNAIEMSEDFDG---KMHDGELEEQEEDDE 4750
+E ED +K ++D + S+ S+ + E+N +E D +G ++H+ L+++ E+++
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEEND 596
Query: 4751 KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEE----EDNKTEETGPGMDEED 4806
+SE D + ++K+ + + + +ED +E ED + DE++
Sbjct: 597 SENSEFED----------DGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKE 646
Query: 4807 SELVAKDDNLDSGNSNKDKSQQDKK-----EEKEEAEADDGGQGEDKINEQIDERDYDEN 4861
E A + L++ + ++ D+K ++KE+ +A DG + ED + ++ D +E
Sbjct: 647 DEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDA-DGKEVEDADEKLFEDDDSNEK 705
Query: 4862 EVDPYHGNQEKV 4873
D + EK+
Sbjct: 706 LFDEEEDSSEKL 717
Score = 48.9 bits (115), Expect = 1e-04
Identities = 74/340 (21%), Positives = 135/340 (39%), Gaps = 26/340 (7%)
Query: 4916 EEAGHEAEER----------GETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQD 4965
EE E EER E S S E + E + + Q+
Sbjct: 356 EETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQE 415
Query: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL 5025
EE +E++ E E +E EN + + + EE + ++EE P+
Sbjct: 416 TATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPK-- 473
Query: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLA 5085
R SC Q E + E +P+KE K+ + + A+ E + +
Sbjct: 474 -RGFEGSCSQKESEEGNPVRGSE--EDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE 530
Query: 5086 SQKH-TRKNTQSFKRKPGQAD-NERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVE 5143
+ T+++ + K D +E+ D +ER + ++ D E+G ++ V
Sbjct: 531 EEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEE-NGLEKDLD-EEGSEKELHENVL 588
Query: 5144 DADAFEHIKQGSDAYDAQTYDVASKE--QQQSAKDSGKDQEEEEIEDTLMDTE--EQEEF 5199
D + E+ + S+ D + V +E +++ +DS + +EEE+ + + D E E+E+
Sbjct: 589 DKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDE 648
Query: 5200 KAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQD 5239
+ AD + L+ + K+ DE E K +ED D
Sbjct: 649 EYADEKGLEAADKKAEEG---DADEKLFEESDDKEDEDAD 685
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 79.0 bits (193), Expect = 1e-13
Identities = 90/356 (25%), Positives = 153/356 (42%), Gaps = 61/356 (17%)
Query: 4683 GEGMKDVSDQIGNEEQVEDTFQKG-QEKDKEDPDSKSDIKGEDNAIEMSED--FDGKMHD 4739
GE + S+ E E ++G EK+ E+ K +G + E E G D
Sbjct: 438 GEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEED 497
Query: 4740 GELEEQEEDDEKSDSEGGDLDKHM-GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEET 4798
+E ++ K+D E L K DLN E +++ ++D+ E E +ED +++
Sbjct: 498 SPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQS 557
Query: 4799 GPGMDEEDSELVAKDDNLDSGNSNKDKSQQ--DKKEEKEEAE----ADDGGQGEDKINEQ 4852
G + E E + D LD S K+ + DK+ E+ ++E DDG E ++E+
Sbjct: 558 EDGSEREFEENGLEKD-LDEEGSEKELHENVLDKELEENDSENSEFEDDGS--EKVLDEE 614
Query: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT-----DNEEGEEEN 4907
ER++DE DS++K EDT D+E E+E+
Sbjct: 615 GSEREFDE---------------------------DSDEKEEEEDTYEKVFDDESDEKED 647
Query: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
+E +E G EA ++ E D +E + ++ ED+ A+G+E D AD++ +
Sbjct: 648 ----EEYADEKGLEAADKKAEEGDADEKLFEESDDK---EDEDADGKEVED--ADEKLFE 698
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGG-------ENGPADQGFQPQEEEEREDSD 5016
E+ +E++ S E+ ++DE G E GP G + +D D
Sbjct: 699 DDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDD 754
Score = 67.8 bits (164), Expect = 3e-10
Identities = 86/352 (24%), Positives = 155/352 (44%), Gaps = 59/352 (16%)
Query: 4711 KEDPDSKSDIKGEDNAIEMSED-FDGKMHDGE----LEEQEEDDEKS---DSEGGDLDKH 4762
+ D S S+ G A SE KM+ E + +E DEK +GG+ ++
Sbjct: 384 RSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEG 443
Query: 4763 MGDLNGEEADKLDERLWGDDDEEEDE---------------EEEDNK---TEETGPGMDE 4804
+ N +E+ E G ++E +E EE N +EE P +
Sbjct: 444 ASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSP--KK 501
Query: 4805 EDSELVAKDDNLDSGNSNKDKSQQDKKEEKE-----EAEADDGGQGED-----KINEQID 4854
E + K+D ++G + + + +K+ E+E E+E DD + D K +E
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 4855 ERDYDENEVD---PYHGNQEKVPE---PEALDLPDDLNLDSEDKNGGEDTDNEEGEEENP 4908
ER+++EN ++ G+++++ E + L+ D N + ED +G E +EEG E
Sbjct: 562 EREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFED-DGSEKVLDEEGSE--- 617
Query: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDA 4968
+E E++ + EE E ++ +E EE E +G E D A++ D D
Sbjct: 618 ---REFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADE----KGLEAADKKAEEGDADE 670
Query: 4969 AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE----DSD 5016
E +E + + ++ ++ADE+ E+ +++ +EE+ E DSD
Sbjct: 671 KLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSD 722
Score = 66.2 bits (160), Expect = 8e-10
Identities = 94/444 (21%), Positives = 169/444 (38%), Gaps = 54/444 (12%)
Query: 4715 DSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDS------EGGDLDKHMGDLNG 4768
D +D + E+ + E E G E +SDS G +H +
Sbjct: 348 DGTTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPS 407
Query: 4769 EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ 4828
E G EE +E++ KTE+ G + E A ++N + K+ +
Sbjct: 408 TSKMNAQETATGMAFEEPIDEKKFEKTEDGG------EFEEGASENNAKESSPEKEAEEG 461
Query: 4829 DKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALD--LPDDLN 4886
++E EE G +G E E +P G++E P+ E+ L +D
Sbjct: 462 CPEKESEEGCPKRGFEGSCSQKES--------EEGNPVRGSEEDSPKKESKKKTLKNDCE 513
Query: 4887 LDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPS 4946
+ K +D + E EE P + E+E D +E +S ++ E S
Sbjct: 514 ENGLAKESEDDLNKESEEEVGPTK----------------ESEEDDSEKESDEDCSEKQS 557
Query: 4947 EDDKAEGEEEMDTGAD-DQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQ 5005
ED EE D D++G + E +++ + + ++ E +++G E ++G
Sbjct: 558 EDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEG-- 615
Query: 5006 PQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE--H 5063
E E EDSD +E+ + E+ + E + + +E A E+ E+
Sbjct: 616 -SEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Query: 5064 GSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQAD-NERSMGDHNERVHKRLR 5122
S + A+G E + A +K + + K + D +E+ D +ER
Sbjct: 675 ESDDKEDEDADGKE----VEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDER-----G 725
Query: 5123 TVDTDSHAEQGPAQQPQAQVEDAD 5146
T+ E+GP + + +D
Sbjct: 726 TLGGFGSVEEGPLSTGSSFILSSD 749
Score = 60.5 bits (145), Expect = 5e-08
Identities = 63/282 (22%), Positives = 121/282 (42%), Gaps = 10/282 (3%)
Query: 4667 EGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNA 4726
EG+ + E G G + + D + G K+ ED +K +
Sbjct: 477 EGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPT 536
Query: 4727 IEMSEDFDGKMHDGEL-EEQEEDDEKSDSEGGDLDKHMGDLNGEEADK-LDERLWGDDDE 4784
E ED K D + E+Q ED + + E L+K DL+ E ++K L E + + E
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEK---DLDEEGSEKELHENVLDKELE 593
Query: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ---DKKEEKEEAEADD 4841
E D E + + + + +DEE SE +D+ D +D ++ D+ +EKE+ E D
Sbjct: 594 ENDSENSEFEDDGSEKVLDEEGSEREFDEDS-DEKEEEEDTYEKVFDDESDEKEDEEYAD 652
Query: 4842 GGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE 4901
+G + +++ +E D DE + +++ + + ++ D+ + +D N + E
Sbjct: 653 E-KGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711
Query: 4902 EGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEE 4943
+ E+ + E+ G + E G T + S + ++
Sbjct: 712 DSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDD 753
Score = 56.2 bits (134), Expect = 9e-07
Identities = 56/252 (22%), Positives = 117/252 (46%), Gaps = 41/252 (16%)
Query: 4652 KGFCLPKEFMEDSAGEGATEF------------HDYEGGGIG---EGEGMKDVSDQIG-N 4695
+G C KE E + G+ E +D E G+ E + K+ +++G
Sbjct: 477 EGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPT 536
Query: 4696 EEQVEDTFQKGQEKDKEDPDSK--SDIKGEDNAIEMSEDFDG---KMHDGELEEQEEDDE 4750
+E ED +K ++D + S+ S+ + E+N +E D +G ++H+ L+++ E+++
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEEND 596
Query: 4751 KSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEE----EDNKTEETGPGMDEED 4806
+SE D + ++K+ + + + +ED +E ED + DE++
Sbjct: 597 SENSEFED----------DGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKE 646
Query: 4807 SELVAKDDNLDSGNSNKDKSQQDKK-----EEKEEAEADDGGQGEDKINEQIDERDYDEN 4861
E A + L++ + ++ D+K ++KE+ +A DG + ED + ++ D +E
Sbjct: 647 DEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDA-DGKEVEDADEKLFEDDDSNEK 705
Query: 4862 EVDPYHGNQEKV 4873
D + EK+
Sbjct: 706 LFDEEEDSSEKL 717
Score = 48.9 bits (115), Expect = 1e-04
Identities = 74/340 (21%), Positives = 135/340 (39%), Gaps = 26/340 (7%)
Query: 4916 EEAGHEAEER----------GETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQD 4965
EE E EER E S S E + E + + Q+
Sbjct: 356 EETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQE 415
Query: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL 5025
EE +E++ E E +E EN + + + EE + ++EE P+
Sbjct: 416 TATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPK-- 473
Query: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLA 5085
R SC Q E + E +P+KE K+ + + A+ E + +
Sbjct: 474 -RGFEGSCSQKESEEGNPVRGSE--EDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE 530
Query: 5086 SQKH-TRKNTQSFKRKPGQAD-NERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVE 5143
+ T+++ + K D +E+ D +ER + ++ D E+G ++ V
Sbjct: 531 EEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEE-NGLEKDLD-EEGSEKELHENVL 588
Query: 5144 DADAFEHIKQGSDAYDAQTYDVASKE--QQQSAKDSGKDQEEEEIEDTLMDTE--EQEEF 5199
D + E+ + S+ D + V +E +++ +DS + +EEE+ + + D E E+E+
Sbjct: 589 DKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDE 648
Query: 5200 KAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQD 5239
+ AD + L+ + K+ DE E K +ED D
Sbjct: 649 EYADEKGLEAADKKAEEG---DADEKLFEESDDKEDEDAD 685
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 79.0 bits (193), Expect = 1e-13
Identities = 101/550 (18%), Positives = 232/550 (42%), Gaps = 29/550 (5%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSE 4755
EE++ + Q+G+ +++E+ + + + + E+ E +L EQEE ++ + +
Sbjct: 261 EERLRE--QEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318
Query: 4756 GGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDN 4815
+ ++ M + E+ + +ERLW ++E+ E++ K + M E+D L K++
Sbjct: 319 MWEQEEKMREQE-EKMWRQEERLW---EQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 4816 LDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDEN---EVDPYHGNQEK 4872
+ ++ ++ ++EE+ + E+ + EQ ++ E E + Q++
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 4873 VPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEE----ENPLEIKEKPEEAGHEAEERGET 4928
+PE + + + E+K ++ + EE E + +EK E + E+ E
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 4929 ETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDK 4988
DQ + QE ++ E EE M ++ EE E++++ E++ K
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERM------REQKKMWQQEEKMREEKKTQEQEKK 548
Query: 4989 EADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAME 5048
D+E E ++ + +E++ RE+ + + E ++ +E Q E M + E
Sbjct: 549 TWDQE--EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE--EKMWEQE--E 602
Query: 5049 LAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNER 5108
EK +EE + ++ + E Q +K + + ++++ + E
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ--EEKMQEQEEKMWEQEEKMREQEE 660
Query: 5109 SMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQG-SDAYDAQTYDVAS 5167
M + E++ + + QG ++ + Q E E G + Q +
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWG 720
Query: 5168 KEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEV 5227
+E+ + ++ +DQ +E++++ L + EE+ ++ +G+ P G + E
Sbjct: 721 QEEMREKEERIRDQ-KEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEG 779
Query: 5228 EIQTVKTEED 5237
Q T ++
Sbjct: 780 SPQDNPTAQE 789
Score = 71.6 bits (174), Expect = 2e-11
Identities = 145/733 (19%), Positives = 293/733 (39%), Gaps = 119/733 (16%)
Query: 4662 EDSAGEGATEFHDYEGGGI-GEGEGMKDVSDQ-IGNEEQVEDTFQKGQEKDKEDPDS--- 4716
++ E +F DY I G G D + I N E T +G +++ +
Sbjct: 19 QNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQ 78
Query: 4717 -----KSDIKGEDNAIEM--------------SEDFDGKMHDGELEEQEEDDEKSDSE-- 4755
+ +I+ +D+ I + S+D K DG L E ++ +
Sbjct: 79 HQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWH 138
Query: 4756 -GGDLDKHMGDLNG--EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAK 4812
G+L + + ++ ++AD+ E L + D E + T E + ++++EL K
Sbjct: 139 FAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE---LKKKNAELQEK 195
Query: 4813 DDNLDSGNSNKDKSQQDKKEEKEEAEA--------------DDGGQGEDKINEQIDERDY 4858
L S K + Q + KE K + E ++ + E+++ EQ E+
Sbjct: 196 ---LRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ--EKKI 250
Query: 4859 DENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEA 4918
+ E + +E++ E E + + ++K E + E E+E L ++K E
Sbjct: 251 RKQEEKMWR-QEERLREQEGKMREQEEKMRRQEKRLREQ-EKELREQEKELREQKKLREQ 308
Query: 4919 GHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEM---DTGADDQDGDAAQHPEEH 4975
+ +E+ E +Q E QE + E+ E E++M + DQ+ + +E
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE-ERMWEQDER 367
Query: 4976 SEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQ 5035
E+++ + E++K ++E E ++ + +E++ RE+ +T + E ++++E Q
Sbjct: 368 LREKEERMREQEKMWEQE--EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 5036 TGVENMQNT---QAMELAGAAPEKEQGKE--EHGSGAADANQAEGHESNFIAQLASQKHT 5090
E Q Q +L +EQ ++ E D + G E Q +K
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ---EKMR 482
Query: 5091 RKNTQSFKRKPGQADNERSMGDHNERV---HKRLRTVDTDSHAEQGPAQQPQAQVEDADA 5147
+ Q ++++ D E+ M D ER+ +RLR + ++ QQ + E+
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 5148 FEHIKQGSDAYDAQTYDVASKEQQ-----------------QSAKDSGKDQEE------- 5183
E K+ D + + +E++ Q ++ ++QEE
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 5184 --EEIEDTLMDTEE-----QEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEE 5236
+E E+ + + EE +EE K + E++ E+ E +++ Q K E
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ------------EEKMQEQEEKMWE 650
Query: 5237 DQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLE-MW 5295
++ ++ K E E+ + +E + + + Q + + E +++ Q E MW
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKM-----QGQEEKMREQEEKMRGQEEKMW 705
Query: 5296 QPRESGNPEEEKV 5308
E +EEK+
Sbjct: 706 GQEEKMWGQEEKM 718
Score = 54.3 bits (129), Expect = 3e-06
Identities = 40/200 (20%), Positives = 101/200 (50%), Gaps = 14/200 (7%)
Query: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDF----DGKMHDGELE 4743
D +++ EE++ + +K +E+++ + + ++ ++ + E+ + KM + E +
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKL---DERLWGDDDEEEDEEEEDNKTEETGP 4800
E++++ + E D + ++ E+ +K+ +E++W +++ ++EE+ + EE
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 4801 GMDEEDSELVAKDDNLDSGNSNKDKSQQDK---KEEKEEAEADDGGQGEDKINEQIDERD 4857
G +E+ + + + G K + Q++K +EEK + + E+K+ Q + R+
Sbjct: 671 GQEEK----MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 4858 YDENEVDPYHGNQEKVPEPE 4877
+E D QE++PE E
Sbjct: 727 KEERIRDQKEKMQERLPEHE 746
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 78.2 bits (191), Expect = 2e-13
Identities = 69/286 (24%), Positives = 117/286 (40%), Gaps = 17/286 (5%)
Query: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDPDS-----------KSDIKGEDNAIE-MSEDFDG 4735
D D+ E+ D E K DP + D GE++ E +SE+ +
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047
Query: 4736 KMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKT 4795
+ E EE+EE+++ D + D D+ D + E+ GD DEEE +K
Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKA 1107
Query: 4796 EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDE 4855
E T E SE + ++ S + ++++ ++EE+EE E + + E
Sbjct: 1108 EATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFE 1167
Query: 4856 RDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKP 4915
+D +E + P + + E +D+ + E + ++ G EE P + +E P
Sbjct: 1168 QDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEE-PADSREPP 1226
Query: 4916 EEAGHEAEE----RGETETDQNESQSPQEPEEGPSEDDKAEGEEEM 4957
EE G E E + E++ P PE P D + E E M
Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPM 1272
Score = 67.0 bits (162), Expect = 5e-10
Identities = 73/290 (25%), Positives = 117/290 (40%), Gaps = 43/290 (14%)
Query: 4781 DDDEEEDEEEEDNKTEETGPGMDEEDSELV------AKDDNLDSGNSNKDKSQQDKKEE- 4833
D+++EE E E D +T + + D + V A+ LDSG +K +++E
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047
Query: 4834 -KEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDK 4892
+EE EA++ + ED ++ D+RD EN D ED
Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDRDESEN--------------------------DDEDT 1081
Query: 4893 NGGEDTDNEEGE--EENPLEIKEKPEEA--GHEAEERGETETDQNESQSPQEPEEGPSED 4948
E ++ +EG+ EE + I EA E+ E E E+ S S E EE
Sbjct: 1082 ALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAR 1141
Query: 4949 DKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQE 5008
++ E EEE + A++ A PE+ ++ +++ A + G D +
Sbjct: 1142 EEEEEEEEEEMVAEESMASAG--PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVA 1199
Query: 5009 EEEREDSDTEEQVPEALERKEHASCGQTGVE-NMQNTQAMELAGAAPEKE 5057
EER E +P +E E A + E + AM L+ P KE
Sbjct: 1200 PEERPSMLDEPPLPVGVE--EPADSREPPEEPGLSQEGAMLLSPEPPAKE 1247
Score = 56.2 bits (134), Expect = 9e-07
Identities = 39/184 (21%), Positives = 80/184 (43%), Gaps = 24/184 (13%)
Query: 4914 KPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEE-------EMDTGADDQDG 4966
+P + E +E E E D++ + +P E + D K G E+D+G ++ +
Sbjct: 982 RPSTSVDEEDEESERERDRDMADTPCELAK---RDPKGVGVRRRPARPLELDSGGEEDEK 1038
Query: 4967 DAAQHPEEHSEEQQQSVEEKDKEADEEG-------GENGPADQGFQPQEEEEREDSDTEE 5019
++ +E +EE++++ EE+++E D++ EN D E++ DSD EE
Sbjct: 1039 ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Query: 5020 QVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESN 5079
V + E S + +++++ E ++ E+ A + E E
Sbjct: 1099 TVSIVTSKAEATS-------SSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEE 1151
Query: 5080 FIAQ 5083
+A+
Sbjct: 1152 MVAE 1155
Score = 53.5 bits (127), Expect = 6e-06
Identities = 42/219 (19%), Positives = 92/219 (42%), Gaps = 15/219 (6%)
Query: 4868 GNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPE-----EAGHEA 4922
G+Q+++ ++D D+ + D++ + + + ++ +P ++G E
Sbjct: 976 GDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEE 1035
Query: 4923 EERG----ETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEE 4978
+E+ E E+ + E ++ +E EE +DD ++ +E + +D A +E +
Sbjct: 1036 DEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSD 1095
Query: 4979 QQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGV 5038
++++V +A+ F+ E S+ EE+V E +E
Sbjct: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEE------ 1149
Query: 5039 ENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077
E M ++M AG ++ G+E + A A + G E
Sbjct: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGME 1188
Score = 51.2 bits (121), Expect = 3e-05
Identities = 49/168 (29%), Positives = 68/168 (40%), Gaps = 10/168 (5%)
Query: 4897 DTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEE 4956
D+ EE E+E+ E +E EE EAEE E E D ++ ++ E ED E
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEE-EEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088
Query: 4957 MDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSD 5016
D G D D + E S E + E E+ P+ EEE +
Sbjct: 1089 KDEG--DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSS---EDEEEVVAREE 1143
Query: 5017 TEEQVPEALERKEH-ASCGQTGVENMQNTQAMELAGAAPEKEQ-GKEE 5062
EE+ E + +E AS G E Q+ + LA AP + G EE
Sbjct: 1144 EEEEEEEEMVAEESMASAGPEDFE--QDGEEAALAPGAPAVDSLGMEE 1189
Score = 34.7 bits (78), Expect = 2.7
Identities = 29/158 (18%), Positives = 64/158 (40%), Gaps = 13/158 (8%)
Query: 5098 KRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDA 5157
+R+P + S G+ +E+ ++ S ++ ++ +A+ E+ + + D
Sbjct: 1020 RRRPARPLELDSGGEEDEK--------ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDR 1071
Query: 5158 YDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTT 5217
+++ D + + S KD G EEE + E + E + E +S +
Sbjct: 1072 DESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE-----ATSSSESSESSEFESSSE 1126
Query: 5218 APLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPE 5255
+ E E E+ + EE+++ A + + PE
Sbjct: 1127 SSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPE 1164
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 78.2 bits (191), Expect = 2e-13
Identities = 82/345 (23%), Positives = 145/345 (42%), Gaps = 51/345 (14%)
Query: 4678 GGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKM 4737
G +GE + + +++ EQ E + D+ ++ G E ++ GK
Sbjct: 4 GAVGESDCSAEAREKM---EQKEGKLSEDGTTVSPAADNP-EMSGGGAPAEETKGTAGKA 59
Query: 4738 HDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDER--LWGDDDEEEDEEEEDNKT 4795
+ + EK+ +E G + G+ NG + K++ + G +D E + ++ED +
Sbjct: 60 INEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEK 119
Query: 4796 EETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDE 4855
EET G E +G + KS+ + EEKE A + + E+K +
Sbjct: 120 EETTVGSQEM------------TGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESG 167
Query: 4856 RDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKP 4915
+ D N+ D PEP+A +D S+++ G E +P
Sbjct: 168 QKADANDRDK--------PEPKATVEEEDAKTASQEETGQRK------------ECSTEP 207
Query: 4916 EEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEG-EEEMDTGADDQDGDAAQHPEE 4974
+E + E + E++ E ++ EP+E +++ G +EE D + +D + A+ P
Sbjct: 208 KEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAE-PGS 266
Query: 4975 HSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
SEEQ+Q VE+ + EGG G P EE +S T E
Sbjct: 267 PSEEQEQDVEK-----EPEGG------AGVIPSSPEEWPESPTGE 300
Score = 61.2 bits (147), Expect = 3e-08
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 31/257 (12%)
Query: 4838 EADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGED 4897
E+D + +K+ ++ + D V P N PE P + + K E
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADN----PEMSGGGAPAEETKGTAGKAINEG 63
Query: 4898 TDNEEGEEENPLEIKEKPEEAGHEAEERGETE-TDQNESQSPQEP---EEGPSEDDKAEG 4953
E G++E + P E G AE +GE D+ + +S +E E+ +E K +G
Sbjct: 64 PPTESGKQE------KAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDG 117
Query: 4954 EEEMDT-GADDQDG---DAAQHPEEHSEEQQQSVEEK----DKEADEEGGENGPADQGFQ 5005
E+E T G+ + G + P+E E++ EK +KEA E G+ A+ +
Sbjct: 118 EKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDK 177
Query: 5006 PQ-----EEEEREDSDTEEQVPE---ALERKEHASCGQTGVENMQNTQAMELAGAAPEKE 5057
P+ EEE+ + + EE + E KE A+ + E+ Q + A A P++
Sbjct: 178 PEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAES-QKAVVEDEAKAEPKEP 236
Query: 5058 QGKEEHGSGAADANQAE 5074
GKEE GA + A+
Sbjct: 237 DGKEEAKHGAKEEADAK 253
Score = 60.8 bits (146), Expect = 4e-08
Identities = 72/299 (24%), Positives = 121/299 (40%), Gaps = 48/299 (16%)
Query: 4819 GNSNKDKSQQDKKEEKEEAEADDG------------GQGEDKINEQIDERDYDENEVDPY 4866
G S+ ++K E+KE ++DG G E NE P
Sbjct: 7 GESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPT 66
Query: 4867 H-GNQEKVPEPEALDLP--------DDLNLDSEDKNGG-EDTD----NEEGEEENPL--- 4909
G QEK P + + D++ ++S+ + GG ED + E+GE+E
Sbjct: 67 ESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGS 126
Query: 4910 -EIKEKPEEAGHEAEERGETE-TDQNESQSPQEPEEGPSEDDKAEGEE----EMDTGADD 4963
E+ + EE E +E E E T +E Q +E E P KA+ + E ++
Sbjct: 127 QEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEE 186
Query: 4964 QDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPE 5023
+D A EE + ++ S E K+K DEE + Q+ +++ E + P+
Sbjct: 187 EDAKTASQ-EETGQRKECSTEPKEKATDEEAKA--------ESQKAVVEDEAKAEPKEPD 237
Query: 5024 ALERKEHASCGQTGV-ENMQNTQAMELAGAAPEKEQGKE---EHGSGAADANQAEGHES 5078
E +H + + E ++ + E + E+EQ E E G+G ++ E ES
Sbjct: 238 GKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPES 296
Score = 60.1 bits (144), Expect = 6e-08
Identities = 73/320 (22%), Positives = 131/320 (40%), Gaps = 44/320 (13%)
Query: 4678 GGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEM----SEDF 4733
GG E K + + NE ++ + QEK + ++++GE N ++ S+
Sbjct: 44 GGGAPAEETKGTAGKAINEGPPTESGK--QEKAPAEDGMSAELQGEANGLDEVKVESQRE 101
Query: 4734 DGKMHDGELEEQEEDDEKSDSEGGDLD----KHMGDLNGEEADKLDERLWGDDDEEEDEE 4789
G D E E ++ED EK ++ G + K +EA++ + L + + E++E
Sbjct: 102 AGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKE 161
Query: 4790 EE----------DNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA 4839
+ D E ++EED++ ++++ +G + ++ +K EEA+A
Sbjct: 162 AKPESGQKADANDRDKPEPKATVEEEDAKTASQEE---TGQRKECSTEPKEKATDEEAKA 218
Query: 4840 DDG-GQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT 4898
+ ED+ + E D E + HG +E+ E + ++ S + +D
Sbjct: 219 ESQKAVVEDEAKAEPKEPDGKE---EAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDV 275
Query: 4899 DNE-EGEE----ENPLEIKEKPEEAGH---------EAEERGETETDQNESQS---PQEP 4941
+ E EG +P E E P GH + G+T +ES PQ P
Sbjct: 276 EKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSP 335
Query: 4942 EEGPSEDDKAEGEEEMDTGA 4961
E PS +K E E A
Sbjct: 336 PESPSSGEKKEKAPERRVSA 355
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 77.4 bits (189), Expect = 4e-13
Identities = 122/589 (20%), Positives = 227/589 (38%), Gaps = 127/589 (21%)
Query: 4705 KGQEKDK--EDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKH 4762
K Q K+K P+S+ +E+S++ + + E EE+EE++E+
Sbjct: 1038 KVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE----------- 1086
Query: 4763 MGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSN 4822
EE D+ +++EEE+EEEE+ + + P + + S + +
Sbjct: 1087 ------EEEDE-------EEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPF----VL 1129
Query: 4823 KDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYD----------ENEVDP------- 4865
K K + ++ + + + +NE D D + E EV+
Sbjct: 1130 KKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVL 1189
Query: 4866 ------YHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEA 4918
G + + E E D N D N +D+ N +EG ++NP +K K +
Sbjct: 1190 RKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCK--QV 1247
Query: 4919 GHEAEERGETETDQNES-------------QSPQEPEEGPSEDDKAEG------------ 4953
+ +RG ++ QN+ ++P EP+E + +++ E
Sbjct: 1248 WPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRI 1307
Query: 4954 EEEM------------------------DTGADDQDGDAAQHPEEHSEEQQQSVEEKDKE 4989
EEE+ +T ++ D PEE EE+++ EE+++E
Sbjct: 1308 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367
Query: 4990 --ADEEGGENGPAD-QGFQPQEEE------EREDS---DTEEQVPEALERKEHASCGQTG 5037
+EEGG N D G + QE+E E+EDS D E+ E E H
Sbjct: 1368 EGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1427
Query: 5038 VENMQNTQAMELAGAAPEKEQGKE--EHGSGAADANQAEGHESNFIAQLASQKHTRKNTQ 5095
E+ + ++ E+ +E KE E+ D N GH + + T
Sbjct: 1428 DEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNS 1487
Query: 5096 SFKRKPG------QADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFE 5149
K G ++D E G+ ++ ++ + + D+ ++G + E A +
Sbjct: 1488 EPKELAGDPEAVPESDEEPPPGEQAQKQDQK-NSKEVDTEFKEGNPATMEIDSETVQAVQ 1546
Query: 5150 HIKQGSDAYDAQTYDVA-SKEQQQSAKDSGKDQEEEEIEDTLMDTEEQE 5197
+ Q S D D A ++E +S ++ + + +I TL D ++ +
Sbjct: 1547 SLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSD 1595
Score = 63.2 bits (152), Expect = 7e-09
Identities = 113/505 (22%), Positives = 189/505 (37%), Gaps = 77/505 (15%)
Query: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGK----MHDGELE 4743
D SD+ Q+E T + E+D P + + + +E+ +GK + +
Sbjct: 1161 DNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPC 1220
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG---- 4799
+D+ S+ + G D E K +++W + + NK +TG
Sbjct: 1221 RNNMNDDSSNLKEGSKDN-------PEPLKC-KQVWPKGTKRGLSKWRQNKERKTGFKLN 1272
Query: 4800 ----PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDE 4855
P E E V ++ ++ S +EE +E GE + ++ +
Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKET-------GEALLPQEENR 1325
Query: 4856 RDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKP 4915
R+ V P EK PE DDL E+ E+ + EE EEE
Sbjct: 1326 REETCAPVSPNTSPGEK---PE-----DDLIKPEEE----EEEEEEEEEEEE-------- 1365
Query: 4916 EEAGHEAEERGETETDQN--ESQSPQEPEEGPSEDDKA------EGEEEMDTGADDQDGD 4967
EE G E E G E D + +SQ +EPE ++D A E EEE + + ++D D
Sbjct: 1366 EEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHD 1425
Query: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGGENGPA--DQGFQPQEEEEREDSDTEEQVPEAL 5025
A + H E + EE +E+ +E EN D QP D +
Sbjct: 1426 ADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLT--- 1482
Query: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAP---EKEQGKEEHGSGAADANQAEGHESNFIA 5082
ASC E + +A+ + P E+ Q +++ S D EG+ A
Sbjct: 1483 -----ASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNP----A 1533
Query: 5083 QLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQV 5142
+ T + QS ++ + D+ + D E + R++ + A+Q P Q +
Sbjct: 1534 TMEIDSETVQAVQSLTQESSEQDD--TFQDCAE-TQEACRSLQNYTRADQSP--QIATTL 1588
Query: 5143 EDADAFEHIKQGSDAYDAQTYDVAS 5167
+D +H S + V S
Sbjct: 1589 DDCQQSDHSSPVSSVHSHPGQSVRS 1613
Score = 52.4 bits (124), Expect = 1e-05
Identities = 94/460 (20%), Positives = 174/460 (37%), Gaps = 56/460 (12%)
Query: 4821 SNKDKSQQDKKEEKE-EAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL 4879
SN S+++++ EKE E + E + E + R + + PE+
Sbjct: 993 SNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESR 1052
Query: 4880 DLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQ 4939
+ + E + + EE +EE E +E+ E+ E EE E E + +S P+
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112
Query: 4940 --EPE------EGPSEDDKAEGEE------EMDTGADDQDGDAAQHPEEHSEEQQ--QSV 4983
+P+ + P K G + + T + + P ++S+E++ +
Sbjct: 1113 LTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQL 1172
Query: 4984 EEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQN 5043
E + EE G + FQ Q ++R+ + E + H N N
Sbjct: 1173 EPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEE-------GKDNHCFKNADPCRNNMN 1225
Query: 5044 TQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQ 5103
+ L KE K+ E + + +++ K Q+ +RK G
Sbjct: 1226 DDSSNL------KEGSKD----------NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGF 1269
Query: 5104 ADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTY 5163
N + + +++ TV+ +G ++E E +K+ +A Q
Sbjct: 1270 KLNLYTPPETPMEPDEQV-TVEEQKETSEGKTSPSPIRIE-----EEVKETGEALLPQE- 1322
Query: 5164 DVASKEQQQSAKDSGKDQEEEEIEDTLM---DTEEQEEFKAADVEQLKPEEIKSGTTA-- 5218
++ ++ A S E+ ED L+ + EE+EE + + E+ + EE + G
Sbjct: 1323 --ENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK 1380
Query: 5219 -PLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERS 5257
P G E E + TE++ R D H+E E E E S
Sbjct: 1381 DPDGAKSQEKEEPEISTEKEDSARLDD-HEEEEEEDEEPS 1419
Score = 44.7 bits (104), Expect = 0.003
Identities = 103/580 (17%), Positives = 207/580 (35%), Gaps = 139/580 (23%)
Query: 4747 EDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNK---TEETGPGMD 4803
E++ +++ E L + EE + L R + + + + NK + E+ P
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTR--ANSRQSPAKVQSKNKYLHSPESRPVTG 1056
Query: 4804 EEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQID--------- 4854
E L ++ + +D+ +++++EE+EE E ++ + E++ E I
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
Query: 4855 ------------------------------ERDYDENEV--DPYHGNQEKVPEPEALDLP 4882
E + EV +P+ + E+ P P+ L+
Sbjct: 1117 QSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQ-LEPT 1175
Query: 4883 DDLNLDSEDK------------NGGEDTDNEEGEEENPLE-------------------I 4911
++ ++ + + T+ EEG++ + +
Sbjct: 1176 CEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGS 1235
Query: 4912 KEKPE-----EAGHEAEERGETETDQNESQSP------QEPEEGPSEDDKAEGEEEMDTG 4960
K+ PE + + +RG ++ QN+ + P E P E D+ EE
Sbjct: 1236 KDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKET 1295
Query: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEE----------GGENGPADQGFQPQEEE 5010
++ + + EE +E +++ +++ EE GE P D +P+EEE
Sbjct: 1296 SEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEK-PEDDLIKPEEEE 1354
Query: 5011 EREDSDTEEQVPEALERKE---------HASCGQTGVENMQNTQAMELAGAAPEKEQGKE 5061
E E+ + EE+ E E +E + Q E +T+ + A +E+ +E
Sbjct: 1355 EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414
Query: 5062 EHGSGAADANQAEGHESNFIAQL---------ASQKHTRKNTQSF---KRKPGQADNERS 5109
+ + + A+ + + + S K +N ++F +PG ++ E
Sbjct: 1415 DEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVL 1474
Query: 5110 M-----------GDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAY 5158
M + E ++D G Q Q Q + K+G+ A
Sbjct: 1475 MDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPA- 1533
Query: 5159 DAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEE 5198
T ++ S+ Q QE E +DT D E +E
Sbjct: 1534 ---TMEIDSETVQAV---QSLTQESSEQDDTFQDCAETQE 1567
Score = 33.9 bits (76), Expect = 4.7
Identities = 72/342 (21%), Positives = 118/342 (34%), Gaps = 53/342 (15%)
Query: 4662 EDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIK 4721
E+ E E + E G EG G + ++ E+ +++D D + +
Sbjct: 1353 EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEE 1412
Query: 4722 GEDNAIEMSEDFDG------KMHDGELEEQEEDDE------KSDSEGGDLDKHMGDLNGE 4769
ED +ED D M E+E++E E ++ DL+ G N E
Sbjct: 1413 EEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPE 1472
Query: 4770 -----------EADKLDERLWGDDD--EEEDEE----------------EEDNKTEETGP 4800
+ + L GD + E DEE E D + +E P
Sbjct: 1473 VLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNP 1532
Query: 4801 GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE-------AEADDGGQGEDKINE-Q 4852
E DSE V +L +S +D + QD E +E AD Q +++ Q
Sbjct: 1533 ATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQ 1592
Query: 4853 IDERDYDENEVDPYHGNQ-EKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEI 4911
+ + V + G V P L + S D++ + + E +P+
Sbjct: 1593 QSDHSSPVSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQS-AISVPSLQNMETSPM-- 1649
Query: 4912 KEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEG 4953
+ P + H + +D +S E E PS D G
Sbjct: 1650 MDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMG 1691
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 75.9 bits (185), Expect = 1e-12
Identities = 105/546 (19%), Positives = 222/546 (40%), Gaps = 73/546 (13%)
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKI 4849
+ED+KT +T ++ AK D ++ G +K EKE+ ++D + K
Sbjct: 1308 KEDDKTTKTIK--EQPQPPCTAKPDQVEPGK---------EKTEKEDDKSDTSSSQQPKS 1356
Query: 4850 NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE-EENP 4908
+ + + Y + + G + + D+ L DS + + ++ + E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDA 4968
L I E +A A+E+ E +T +E SP++P++ +E+ + ++ +
Sbjct: 1417 LSILEA--QASTLADEKSEKKTQPHEV-SPEQPKD----------QEKTQSLSETLEITI 1463
Query: 4969 AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL--- 5025
++ + S+E+++ +KD + D ++ F RE D+ E+ E+
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 5026 --ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQ 5083
+RK S G + + + + G+ E++ +++ +AD + + + FI
Sbjct: 1524 VPQRKRRTSVGSSSSDEYKQEDSQ---GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN 1580
Query: 5084 LASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDS------HAEQGPA-- 5135
K +T+S K++ + + + G H K ++D D+ H E A
Sbjct: 1581 --QLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFD 1638
Query: 5136 QQPQAQVEDADAFEH----IKQGSDAYDAQTYDVASK-EQQQSAKDSGKD-----QEEEE 5185
+ P+ + + + E + G +T ++ S + SA+ S K EE E
Sbjct: 1639 ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPE 1698
Query: 5186 IEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKA 5245
+E + ++ + L GT+ T + D+D + +
Sbjct: 1699 LEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP------------TSVSSLDEDSDSSPS 1746
Query: 5246 HKETENEKPERSRESTIHTAHQFLMDTIF----QPFLKDVNELRQELERQLEMWQPRESG 5301
HK+ E+++ ++R H H L+ TI + L++ EL +E E+Q E+ Q +
Sbjct: 1747 HKKGESKQQRKAR----HRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKS 1802
Query: 5302 NPEEEK 5307
+ ++ K
Sbjct: 1803 SSKKSK 1808
Score = 45.1 bits (105), Expect = 0.002
Identities = 103/536 (19%), Positives = 189/536 (35%), Gaps = 94/536 (17%)
Query: 4697 EQVEDTFQKGQ-EKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHD-GELEEQEEDDEK--- 4751
+QVE +K + E DK D S K + DG GE+ DEK
Sbjct: 1330 DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 4752 ------------SDSEGGDLDKH----MGDLNGEE---ADKLDERLWGDDDEEEDEEEED 4792
S S DL K + L + AD+ E+ + ++ ++
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ 1449
Query: 4793 NKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKK---EEKEEAEADDGGQGEDKI 4849
KT+ ++ SE K+ + ++ K SQQD + KE++E D +
Sbjct: 1450 EKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Query: 4850 NEQIDERDYDENEVDPYH----------------------GNQEKVPEPEALDLPDDLNL 4887
+ ++E EN P G +E + +++ D
Sbjct: 1510 YDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSAD--- 1566
Query: 4888 DSEDKNGGEDTD---NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEG 4944
ED +G ED + N+ E + E ++K E G G+ +S + + + G
Sbjct: 1567 --EDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAG 1624
Query: 4945 PSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQ-------------SVEEKDKEAD 4991
E +E D + ++ E S+E ++ ++E AD
Sbjct: 1625 RRHSWHDEDDEAFD------ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 4992 EEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE-----HASCGQTGVENMQNTQA 5046
+ E+ EE E E + PE R E HAS G +
Sbjct: 1679 KYSAESSQKKTSLYFDEEPELEMESLTDS-PEDRSRGEGSSSLHASSFTPGTSPTSVSSL 1737
Query: 5047 MELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
E + ++P ++G+ + A ++ G I + ++ R+ + K + Q +
Sbjct: 1738 DEDSDSSPSHKKGESKQQRKA--RHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREI 1795
Query: 5107 ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ------AQVEDADAFEHIKQGSD 5156
E+ + + K+ D D Q ++P+ + +EDA E ++Q ++
Sbjct: 1796 EQQQRKSSSKKSKK----DKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAE 1847
Score = 44.3 bits (103), Expect = 0.003
Identities = 79/428 (18%), Positives = 156/428 (36%), Gaps = 56/428 (13%)
Query: 4871 EKVPEPEALD-LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE 4929
EKV E +++ +P + D + + + D +E K PEE EE E
Sbjct: 1174 EKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK----KPLPEEKKLIPEE----E 1225
Query: 4930 TDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQS------- 4982
++E + P E+ P+ +DK E + ++Q D + + +EE+ +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTV 1285
Query: 4983 VEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQ 5042
E K + EG +G P+E+++ + E+ P + + G+ E +
Sbjct: 1286 QEGKQPQTKMEGLPSGTPQS--LPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEK-E 1342
Query: 5043 NTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIA--QLASQKHTRKNTQSFKRK 5100
+ ++ + P+ QG + G + + + G + I + K +K++ S +
Sbjct: 1343 DDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESS 1402
Query: 5101 PGQADN---------------ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDA 5145
P + ++ D + V + +Q Q +E
Sbjct: 1403 PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEIT 1462
Query: 5146 DAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLM-------DTEEQEE 5198
+ E IK+ + + D K+ QQ S +E+ E D + EE E
Sbjct: 1463 ISEEEIKESQE----ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
Query: 5199 FKAADVEQLK---------PEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKET 5249
+ + V Q K +E K + G +E + Q ++ D+D + +
Sbjct: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
Query: 5250 ENEKPERS 5257
N+ E S
Sbjct: 1579 RNQLKEIS 1586
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.9 bits (185), Expect = 1e-12
Identities = 105/546 (19%), Positives = 222/546 (40%), Gaps = 73/546 (13%)
Query: 4790 EEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKI 4849
+ED+KT +T ++ AK D ++ G +K EKE+ ++D + K
Sbjct: 1308 KEDDKTTKTIK--EQPQPPCTAKPDQVEPGK---------EKTEKEDDKSDTSSSQQPKS 1356
Query: 4850 NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE-EENP 4908
+ + + Y + + G + + D+ L DS + + ++ + E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDA 4968
L I E +A A+E+ E +T +E SP++P++ +E+ + ++ +
Sbjct: 1417 LSILEA--QASTLADEKSEKKTQPHEV-SPEQPKD----------QEKTQSLSETLEITI 1463
Query: 4969 AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL--- 5025
++ + S+E+++ +KD + D ++ F RE D+ E+ E+
Sbjct: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSP 1523
Query: 5026 --ERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQ 5083
+RK S G + + + + G+ E++ +++ +AD + + + FI
Sbjct: 1524 VPQRKRRTSVGSSSSDEYKQEDSQ---GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN 1580
Query: 5084 LASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDS------HAEQGPA-- 5135
K +T+S K++ + + + G H K ++D D+ H E A
Sbjct: 1581 --QLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFD 1638
Query: 5136 QQPQAQVEDADAFEH----IKQGSDAYDAQTYDVASK-EQQQSAKDSGKD-----QEEEE 5185
+ P+ + + + E + G +T ++ S + SA+ S K EE E
Sbjct: 1639 ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPE 1698
Query: 5186 IEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKA 5245
+E + ++ + L GT+ T + D+D + +
Sbjct: 1699 LEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP------------TSVSSLDEDSDSSPS 1746
Query: 5246 HKETENEKPERSRESTIHTAHQFLMDTIF----QPFLKDVNELRQELERQLEMWQPRESG 5301
HK+ E+++ ++R H H L+ TI + L++ EL +E E+Q E+ Q +
Sbjct: 1747 HKKGESKQQRKAR----HRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKS 1802
Query: 5302 NPEEEK 5307
+ ++ K
Sbjct: 1803 SSKKSK 1808
Score = 45.1 bits (105), Expect = 0.002
Identities = 103/536 (19%), Positives = 189/536 (35%), Gaps = 94/536 (17%)
Query: 4697 EQVEDTFQKGQ-EKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHD-GELEEQEEDDEK--- 4751
+QVE +K + E DK D S K + DG GE+ DEK
Sbjct: 1330 DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 4752 ------------SDSEGGDLDKH----MGDLNGEE---ADKLDERLWGDDDEEEDEEEED 4792
S S DL K + L + AD+ E+ + ++ ++
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ 1449
Query: 4793 NKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKK---EEKEEAEADDGGQGEDKI 4849
KT+ ++ SE K+ + ++ K SQQD + KE++E D +
Sbjct: 1450 EKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Query: 4850 NEQIDERDYDENEVDPYH----------------------GNQEKVPEPEALDLPDDLNL 4887
+ ++E EN P G +E + +++ D
Sbjct: 1510 YDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSAD--- 1566
Query: 4888 DSEDKNGGEDTD---NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEG 4944
ED +G ED + N+ E + E ++K E G G+ +S + + + G
Sbjct: 1567 --EDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAG 1624
Query: 4945 PSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQ-------------SVEEKDKEAD 4991
E +E D + ++ E S+E ++ ++E AD
Sbjct: 1625 RRHSWHDEDDEAFD------ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 4992 EEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE-----HASCGQTGVENMQNTQA 5046
+ E+ EE E E + PE R E HAS G +
Sbjct: 1679 KYSAESSQKKTSLYFDEEPELEMESLTDS-PEDRSRGEGSSSLHASSFTPGTSPTSVSSL 1737
Query: 5047 MELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
E + ++P ++G+ + A ++ G I + ++ R+ + K + Q +
Sbjct: 1738 DEDSDSSPSHKKGESKQQRKA--RHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREI 1795
Query: 5107 ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ------AQVEDADAFEHIKQGSD 5156
E+ + + K+ D D Q ++P+ + +EDA E ++Q ++
Sbjct: 1796 EQQQRKSSSKKSKK----DKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAE 1847
Score = 44.3 bits (103), Expect = 0.003
Identities = 79/428 (18%), Positives = 156/428 (36%), Gaps = 56/428 (13%)
Query: 4871 EKVPEPEALD-LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE 4929
EKV E +++ +P + D + + + D +E K PEE EE E
Sbjct: 1174 EKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK----KPLPEEKKLIPEE----E 1225
Query: 4930 TDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQS------- 4982
++E + P E+ P+ +DK E + ++Q D + + +EE+ +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTV 1285
Query: 4983 VEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQ 5042
E K + EG +G P+E+++ + E+ P + + G+ E +
Sbjct: 1286 QEGKQPQTKMEGLPSGTPQS--LPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEK-E 1342
Query: 5043 NTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIA--QLASQKHTRKNTQSFKRK 5100
+ ++ + P+ QG + G + + + G + I + K +K++ S +
Sbjct: 1343 DDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESS 1402
Query: 5101 PGQADN---------------ERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDA 5145
P + ++ D + V + +Q Q +E
Sbjct: 1403 PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEIT 1462
Query: 5146 DAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLM-------DTEEQEE 5198
+ E IK+ + + D K+ QQ S +E+ E D + EE E
Sbjct: 1463 ISEEEIKESQE----ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
Query: 5199 FKAADVEQLK---------PEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKET 5249
+ + V Q K +E K + G +E + Q ++ D+D + +
Sbjct: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
Query: 5250 ENEKPERS 5257
N+ E S
Sbjct: 1579 RNQLKEIS 1586
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 73.9 bits (180), Expect = 4e-12
Identities = 74/346 (21%), Positives = 156/346 (45%), Gaps = 28/346 (8%)
Query: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDF----DGKMHDGE--LEEQEEDD 4749
EE++++ +K QE++++ + + I+ ++ + E+ + KM E + E+EE
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 4750 EKSDSEGGDLDKHMGDLNGE--EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE-- 4805
+ + + ++ + +L + E +K+ E+ +EE+ E+E + +E EE
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 4806 --DSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEV 4863
E + + + K Q+ +EE++ E ++ + E+KI EQ E + + E
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ--EEIWRQKE- 543
Query: 4864 DPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAE 4923
H +EK+ + E + + E + E+ E+ EE +EK E +
Sbjct: 544 -KIHEQEEKIRKQE-----EKMWRQEEKMHDQEEKIREQ--EEKVWRQEEKIREQEEKIR 595
Query: 4924 ERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSV 4983
E+ E +Q E QE + G E+ E EE+M + + + EE EQ++ +
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM-----QEQEEKMRRQEEKIREQEKKI 650
Query: 4984 EEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE 5029
E++++ E+ ++ QEE+ E + ++ E + R+E
Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 69.7 bits (169), Expect = 8e-11
Identities = 101/552 (18%), Positives = 234/552 (42%), Gaps = 64/552 (11%)
Query: 4730 SEDFDGKMHD-----GELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDE 4784
+ D ++HD GELE+ + D+++ +L +E D L L+ +
Sbjct: 221 ARDLISRLHDSWKFAGELEQALSAVATQKKKA---DRYIEELT-KERDALSLELYRNTIT 276
Query: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ 4844
+E+ +E++ K +E ++ E SE+ N+ ++++ +++ +AEAD G+
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQL---NVKELKRKLERAKLLLPQQQLQAEADHLGK 333
Query: 4845 GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE 4904
++ ++ + +ENE L + LN E+K ++ +E E
Sbjct: 334 ELQSVSAKL-QAQVEENE------------------LWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 4905 E---ENPLEIKEKPEEAGHEAEE--RGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
E E +I+E+ E+ + E+ R E + E + ++ E +++K +EEM
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 4960 GADD--QDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDT 5017
++ ++ + H +E EQ++ +E++K ++E + A Q ++ E+E+
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 5018 EEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077
E++ E + R+E Q + + Q E EK + +EE ++ E
Sbjct: 495 EQE--EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE--- 549
Query: 5078 SNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQ 5137
+K ++ + ++++ D E + + E+V ++ + ++ ++
Sbjct: 550 ---------EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI----REQEEKIRE 596
Query: 5138 PQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQE 5197
+ ++ + + E ++ + Q + +E++ ++ ++EE+I + EQE
Sbjct: 597 QEEKIREQE--EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 5198 EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERS 5257
E E ++ +E K + E ++ Q K +E ++ + K E E R
Sbjct: 655 EKIREQEEMMQEQEEK------MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 5258 RESTIHTAHQFL 5269
+E + + L
Sbjct: 709 QEEKMQEHQEHL 720
Score = 56.2 bits (134), Expect = 9e-07
Identities = 64/360 (17%), Positives = 144/360 (40%), Gaps = 27/360 (7%)
Query: 4954 EEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERE 5013
E E+ + Q + EE +E ++ ++E++++ E+ + ++ + QEE E
Sbjct: 348 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 407
Query: 5014 DSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQA 5073
+ + E + KE Q + + + EL E+E+ +E+ +
Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 5074 EGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQG 5133
E + Q K R+ + +++ + E M E++H++ + + + EQ
Sbjct: 468 EQEKR----QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 5134 PAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDT 5193
+ + ++ + + K+ + + K +Q K ++++ E E+ +
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 5194 EE-----QEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKE 5248
EE +E+ + + + + EE+ +G E ++ Q K +E ++ + K
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 5249 TENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKV 5308
E EK R +E I ++ E+ QE E +MW+ E +EEK+
Sbjct: 644 REQEKKIREQEEKI----------------REQEEMMQEQEE--KMWEQEEKMCEQEEKM 685
Score = 54.7 bits (130), Expect = 3e-06
Identities = 54/290 (18%), Positives = 127/290 (43%), Gaps = 21/290 (7%)
Query: 4684 EGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE 4743
E ++++ +++ +E++ + +K QE++K K + E A ++ + + ++
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIR 494
Query: 4744 EQEEDDEKSDSEGGDLDKHMGDLNGEEADKL---------DERLWGDDDEEEDEEEEDNK 4794
EQEE + + + + +K + +E +++ E +W ++ ++EE+ K
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 4795 TEETGPGMDE---EDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE---AEADDGGQGEDK 4848
EE +E + E + + + K + Q++K E+EE + + + E+K
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 4849 INEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENP 4908
+ EQ ++ E ++ +EK+ E + + +++ E + + +EE
Sbjct: 615 MGEQEEKMCEQEEKMQE---QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMD 4958
E +EK E + +E+ E Q E QE E+ E +E ++
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 43.1 bits (100), Expect = 0.008
Identities = 68/381 (17%), Positives = 160/381 (41%), Gaps = 47/381 (12%)
Query: 4971 HPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEH 5030
HP+ + + + K K+ + G E+E++ +E + LE + H
Sbjct: 132 HPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVH 191
Query: 5031 A----SCGQTGVENMQNTQAMELAGAAPEKEQGK-EEHGSGAADANQAEGHESNFIAQLA 5085
+C +T ++ A+ + A ++ +G+ + S D+ + G ++ +A
Sbjct: 192 TIRILTCQKTELQ-----MALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVA 246
Query: 5086 SQKHTRKNTQSFKRKPGQAD-----------NERSMGDHNERVHKRLRTVDTDSHAEQGP 5134
+QK +K + + + D + + + N ++ ++L+ V+++ Q
Sbjct: 247 TQK--KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 304
Query: 5135 AQQPQAQVEDADAF---EHIKQGSDAYDAQTYDVASKEQQQSAKDS-----GKDQE---- 5182
++ + ++E A + ++ +D + V++K Q Q ++ + QE
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364
Query: 5183 --EEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDP 5240
EE+I++ +EQEE E+++ +E K + +++ E + + EE
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE---KMRRQEEMMWE 421
Query: 5241 RTDKAHKETEN--EKPERSR--ESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQ 5296
+ +K ++ E EK E+ R E +H + + + + E + E++ +MW+
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 5297 PRESGNPEEEKVAAE---MWQ 5314
E +EEK+ + MW+
Sbjct: 482 QEEKIREQEEKIREQEEKMWR 502
Score = 34.7 bits (78), Expect = 2.7
Identities = 37/192 (19%), Positives = 80/192 (41%), Gaps = 9/192 (4%)
Query: 5132 QGPAQQPQAQVEDADAFEHIKQGSDA----YDAQTYDVASKEQQQSAKDSGKDQEEEEIE 5187
Q + + QAQVE+ + + + Q + + + + K Q+Q K ++++ E E
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 5188 DTLMDTEE----QEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTD 5243
+ + EE +EE E + +E K + +++ E + + +Q+ +
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 5244 KAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNP 5303
+ K E EK + A + + + + + E +++ RQ E +E
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 5304 EEEK-VAAEMWQ 5314
EE++ EMW+
Sbjct: 516 EEKRQEQEEMWR 527
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 73.9 bits (180), Expect = 4e-12
Identities = 87/366 (23%), Positives = 152/366 (41%), Gaps = 51/366 (13%)
Query: 4705 KGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE-----------EQEEDDEKSD 4753
K Q K+ D + E +E D H GE + + EE+ + +
Sbjct: 166 KKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQE 225
Query: 4754 SEGGDLDKHMGDLNGEEADK----------LDERLWGDDDEEEDEEEEDNKTEETGPGMD 4803
+L+ E A+K L+ RLW ++ +E EEE E P ++
Sbjct: 226 DYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQE---PPLE 282
Query: 4804 EEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEV 4863
E + + +L++ + +++ ++EE+E EA++ + ++ Q + E
Sbjct: 283 AERAPREEQQRSLEA--PGWEDAERREREERERLEAEEERR---RLQAQAQAEERRRLEE 337
Query: 4864 DPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEA--GHE 4921
D + + E E + + E+ G E+ + +E E + P E E+ E G E
Sbjct: 338 DARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAE 397
Query: 4922 AEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQ 4981
E+ GE ++ E Q+ E G + + EE + +DQ+ + EHSEE
Sbjct: 398 EEDLGE---EEEEGQAHLEDWRGQLSELLNDFEERL----EDQERLKPEGQREHSEE-PG 449
Query: 4982 SVEEKDKEAD---EEGGENGPADQGFQPQEEEEREDSDTE---------EQVPEALERKE 5029
EE++ EA+ E+ G +G +P EE+RE+ DTE E +ERKE
Sbjct: 450 ICEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKE 509
Query: 5030 HASCGQ 5035
A+ Q
Sbjct: 510 AAALEQ 515
Score = 58.2 bits (139), Expect = 2e-07
Identities = 83/339 (24%), Positives = 141/339 (41%), Gaps = 62/339 (18%)
Query: 4769 EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKS-- 4826
+ K RL D E+ E ++ G +++ + + + LDS + +
Sbjct: 168 QRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDY 227
Query: 4827 --QQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEP--EALDLP 4882
+ + K ++++AEA + + E++ + ++ R ++EN + + EP EA P
Sbjct: 228 WRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAP 287
Query: 4883 DDLNLDSEDKNGGEDTDNE--------EGEEENPLEIKEKPEEAGHEAEERGETETDQN- 4933
+ S + G ED + E EEE + +A +AEER E D
Sbjct: 288 REEQQRSLEAPGWEDAERREREERERLEAEEE------RRRLQAQAQAEERRRLEEDARL 341
Query: 4934 ESQSPQEPEEG-------PSEDDKAEGEEEMDTGADDQDGDAAQHPE--EHSEEQQQSVE 4984
E + QE EEG E+++AEG EE+ + Q+ + PE E + E ++ E
Sbjct: 342 EERRRQEEEEGRCAEELKRQEEEEAEGWEEL----EQQEAEVQGPPEALEETGEGRRGAE 397
Query: 4985 EKDKEADEEGGENGPADQGFQPQE-----EEEREDSD----------------TEEQVPE 5023
E+D +EE G+ D Q E EE ED + EEQ PE
Sbjct: 398 EEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPE 457
Query: 5024 ALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE 5062
A R+E G++G + Q + G ++E+G E
Sbjct: 458 AERRREQQ--GRSG-----DFQGADRPGPEEKREEGDTE 489
Score = 47.0 bits (110), Expect = 5e-04
Identities = 61/297 (20%), Positives = 114/297 (38%), Gaps = 41/297 (13%)
Query: 4891 DKNGGEDTDNEEGE-EENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDD 4949
++N ++ EEGE +E PLE + P E + E E + + +E E E
Sbjct: 262 EENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERR 321
Query: 4950 KAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEE 5009
+ + + + + ++ + EE+ + EE ++ +EE +G++ E+
Sbjct: 322 RLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEA-------EGWEELEQ 374
Query: 5010 EEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAAD 5069
+E E + PEALE +TG E A E++ G+EE G A
Sbjct: 375 QEAE----VQGPPEALE--------ETG----------EGRRGAEEEDLGEEEE-EGQAH 411
Query: 5070 ANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMG---DHNERVHKRLRTVDT 5126
G +++L + R Q + GQ ++ G + N +R
Sbjct: 412 LEDWRGQ----LSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGR 467
Query: 5127 DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEE 5183
+ P+ + E+ D +KQ AQ + ++ +A + G+ EE
Sbjct: 468 SGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQP---PVERKEAAALEQGRKVEE 521
Score = 44.7 bits (104), Expect = 0.003
Identities = 94/451 (20%), Positives = 167/451 (37%), Gaps = 86/451 (19%)
Query: 4893 NGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE-------------TDQNESQSPQ 4939
N GE + E+ +P+EI + + +AE + ++ E +P
Sbjct: 63 NSGEASLEEDLFLTSPMEIVTQQDIVLSDAENKSSDTPSSLSPLNLPGAGSEMEEKVAPV 122
Query: 4940 EPEEGPSEDDKAEGEEEMDTGADDQ-----DGDAAQH-----PEEHSEEQQQSVEEKDKE 4989
+P A E ++ A D AA+H P++ ++ +D +
Sbjct: 123 KPSRPKRHFSSAGTIESVNLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKKHRRLAQDPQ 182
Query: 4990 ADEEGGENGPA-DQGFQP--------QEEEEREDSDTEEQVPEALERKEHASCGQTGVEN 5040
++ G E+ P DQ P +EE DS+ E + E R+ A C + E
Sbjct: 183 HEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEA 242
Query: 5041 MQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRK 5100
+ + E A E+ +E + + EG E A+ A ++ +++ ++
Sbjct: 243 AEKRRLEEQRLQALERRLWEENRRQELLE-EEGEGQEPPLEAERAPREEQQRSLEA---- 297
Query: 5101 PGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDA 5160
PG D ER + ER+ E+ Q QAQ E+ E
Sbjct: 298 PGWEDAERREREERERLEAE----------EERRRLQAQAQAEERRRLEE---------- 337
Query: 5161 QTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPL 5220
D +E+++ ++ G+ EE + QEE +A E+L+ +E + P
Sbjct: 338 ---DARLEERRRQEEEEGRCAEE---------LKRQEEEEAEGWEELEQQEAE--VQGPP 383
Query: 5221 GFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKD 5280
E E + EED ++ E+ + + S + L D F+ L+D
Sbjct: 384 EALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLS---------ELLND--FEERLED 432
Query: 5281 VNELRQELERQLEMWQPRESGNPEEEKVAAE 5311
L+ E +R+ E G EE+ AE
Sbjct: 433 QERLKPEGQRE----HSEEPGICEEQNPEAE 459
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 73.2 bits (178), Expect = 7e-12
Identities = 106/503 (21%), Positives = 193/503 (38%), Gaps = 93/503 (18%)
Query: 4658 KEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSK 4717
KE E+ + +EF I E G+ V +I E+Q +K ++ KE P+ +
Sbjct: 748 KEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQ-----EKHIKESKEKPEKR 802
Query: 4718 SDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDER 4777
S IK E+D EK + + + +K + + E DKLD
Sbjct: 803 SQIK------------------------EKDIEKMERKTFEKEKKIKHEHKSEKDKLDLS 838
Query: 4778 LWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEA 4837
D +E+D+ + + G +++ + K D+ + D+ +K EKE
Sbjct: 839 ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 898
Query: 4838 EADDGGQG-EDKINEQIDERDYDEN------EVDPYHGNQEKVPEPEALDLPDDLNLDSE 4890
A+ + +K N+Q D +Y ++ E D +EK + E++++ + ++ E
Sbjct: 899 LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEE 958
Query: 4891 DKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDK 4950
K+ D + + E PL +KEK ++ P + +G +D K
Sbjct: 959 KKS--SIVDGNKAQHEKPLSLKEKTKD-------------------EPLKTPDGKEKDKK 997
Query: 4951 AEGEEEMDTGADDQDGDAAQHPEEHSEE-QQQSVEEKDKEADEEGGENGPADQGFQPQEE 5009
D+D D + ++H ++ Q S+ + EAD+ ++ PA + +P+E+
Sbjct: 998 ------------DKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEK 1045
Query: 5010 EEREDS----------DTEEQVPEALERKEHASCGQTGVENMQNTQAMEL-------AGA 5052
D ++ E +K Q E ++N +EL
Sbjct: 1046 RLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKH 1105
Query: 5053 APEKEQGKE---EHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN--E 5107
P + + KE S DA E + ++ SQ KN + + +DN
Sbjct: 1106 TPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN-RSQSVDTKNVMTLGKSSFVSDNSLN 1164
Query: 5108 RSMGDHNERVHKRLRTVDTDSHA 5130
RS NE+ R+V S A
Sbjct: 1165 RSPRSENEKPGLSSRSVSMISVA 1187
Score = 52.0 bits (123), Expect = 2e-05
Identities = 113/632 (17%), Positives = 241/632 (38%), Gaps = 102/632 (16%)
Query: 4695 NEEQVEDTFQKGQEKD------KEDPDSKSDIKGEDNAIEMSEDFD---GKMHDGE--LE 4743
N V++ EKD K+ SK+ + + E +D D KM D L
Sbjct: 300 NPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILR 359
Query: 4744 EQEEDDEKSDSEGGDL----DKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG 4799
+++ + + ++E L +K + + + R+ E DEE NK T
Sbjct: 360 KEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTS 419
Query: 4800 PGMDEEDS--------ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINE 4851
+ E S E V ++ G + Q+K +E +E + + G+ +I
Sbjct: 420 CSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITN 479
Query: 4852 QIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEG---EEENP 4908
D +E GN K P+ DD +L + G+ + G ++ P
Sbjct: 480 LTVNTGLDCSEKTREEGNFRKSFSPK-----DDTSLHLFHISTGKSPKHSCGLSEKQSTP 534
Query: 4909 L--------------EIKEKPEEAGHEAEE----------RGETETDQNESQSPQEPEEG 4944
L E+ +P+ ++ E + ++++ Q E G
Sbjct: 535 LKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFG 594
Query: 4945 PSEDDKAEGEEEMDTGAD--------DQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGE 4996
+ K + E+ T + D++G + + +E+++ +K+ E ++E +
Sbjct: 595 EKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYK 654
Query: 4997 NGPADQGFQPQEEEER----EDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGA 5052
+ + Q E +R E+ ++ + EH S T + + + ++ +
Sbjct: 655 TKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESL--TLEKKSKLEKNIKDDKS 712
Query: 5053 APEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP----GQADNER 5108
EK KE + D + E +S ++ K R+N + K G + E
Sbjct: 713 TKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEE 772
Query: 5109 SMGDHNERVHKRLRTVDTDSHAEQGPAQ-QPQAQVEDADAFEHIKQGSDAYDAQTYDVAS 5167
S+G H V K + + H ++ + + ++Q+++ D + + +T+
Sbjct: 773 SIGLH--LVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDI--------EKMERKTF---- 818
Query: 5168 KEQQQSAKDSGKDQEEE-EIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEME 5226
E+++ K K ++++ ++ + + +E+++ + E+ E KS TA
Sbjct: 819 -EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTA-------- 869
Query: 5227 VEIQTVKTEEDQDPRTDKAHKETENEKPERSR 5258
+K +D++ +K ++ + EKPE+ R
Sbjct: 870 ----AIKKTDDREKSREKMDRKHDKEKPEKER 897
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 216,965,771
Number of Sequences: 37866
Number of extensions: 10349431
Number of successful extensions: 88460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 378
Number of HSP's successfully gapped in prelim test: 1069
Number of HSP's that attempted gapping in prelim test: 42210
Number of HSP's gapped (non-prelim): 21410
length of query: 5596
length of database: 18,247,518
effective HSP length: 125
effective length of query: 5471
effective length of database: 13,514,268
effective search space: 73936560228
effective search space used: 73936560228
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.