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Search of human proteins with 22035556
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22035556 transcription initiation factor IIIB isoform 1
[Homo sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22035556 transcription initiation factor IIIB isoform 1 [Homo... 1347 0.0
gi|22035558 transcription initiation factor IIIB isoform 3 [Homo... 933 0.0
gi|4504193 general transcription factor IIB [Homo sapiens] 75 2e-13
gi|22035562 RNA polymerase III transcription initiation factor B... 52 2e-06
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 44 4e-04
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 44 4e-04
gi|4505999 protein phosphatase 1G [Homo sapiens] 42 0.002
gi|29826282 protein phosphatase 1G [Homo sapiens] 42 0.002
gi|83921609 hypothetical protein LOC127254 [Homo sapiens] 40 0.009
gi|16933557 dachsous 1 precursor [Homo sapiens] 39 0.012
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 39 0.016
gi|221219024 pleckstrin homology-like domain, family B, member 1... 39 0.021
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 39 0.021
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.021
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.021
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.027
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.027
gi|81295809 pericentrin [Homo sapiens] 38 0.035
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.035
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 37 0.046
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 37 0.046
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 37 0.060
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 37 0.060
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 37 0.060
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 37 0.078
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 37 0.078
gi|24431975 hypothetical protein LOC26148 [Homo sapiens] 37 0.078
gi|30581160 ganglioside-induced differentiation-associated prote... 37 0.078
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 36 0.10
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 36 0.10
>gi|22035556 transcription initiation factor IIIB isoform 1 [Homo
sapiens]
Length = 677
Score = 1347 bits (3485), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSL 60
MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSL
Sbjct: 1 MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSL 60
Query: 61 DGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSR 120
DGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSR
Sbjct: 61 DGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSR 120
Query: 121 HLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPA 180
HLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPA
Sbjct: 121 HLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPA 180
Query: 181 IDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMH 240
IDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMH
Sbjct: 181 IDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMH 240
Query: 241 DFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRK 300
DFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRK
Sbjct: 241 DFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRK 300
Query: 301 LRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLC 360
LRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLC
Sbjct: 301 LRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLC 360
Query: 361 GEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAAS 420
GEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAAS
Sbjct: 361 GEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAAS 420
Query: 421 LGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAE 480
LGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAE
Sbjct: 421 LGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAE 480
Query: 481 YLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINY 540
YLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINY
Sbjct: 481 YLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINY 540
Query: 541 SVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQP 600
SVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQP
Sbjct: 541 SVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQP 600
Query: 601 AKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQ 660
AKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQ
Sbjct: 601 AKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQ 660
Query: 661 MMGSNDYGCDGDEDDGY 677
MMGSNDYGCDGDEDDGY
Sbjct: 661 MMGSNDYGCDGDEDDGY 677
>gi|22035558 transcription initiation factor IIIB isoform 3 [Homo
sapiens]
Length = 473
Score = 933 bits (2411), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 205 MTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRL 264
MTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRL
Sbjct: 1 MTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRL 60
Query: 265 TEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSY 324
TEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSY
Sbjct: 61 TEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSY 120
Query: 325 QDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRE 384
QDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRE
Sbjct: 121 QDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRE 180
Query: 385 LLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGD 444
LLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGD
Sbjct: 181 LLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGD 240
Query: 445 GELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEH 504
GELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEH
Sbjct: 241 GELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEH 300
Query: 505 KPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHS 564
KPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHS
Sbjct: 301 KPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHS 360
Query: 565 ASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARP 624
ASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARP
Sbjct: 361 ASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARP 420
Query: 625 QAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY 677
QAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY
Sbjct: 421 QAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY 473
>gi|4504193 general transcription factor IIB [Homo sapiens]
Length = 316
Score = 75.5 bits (184), Expect = 2e-13
Identities = 62/268 (23%), Positives = 117/268 (43%), Gaps = 28/268 (10%)
Query: 17 DAARGDAVCTACGSVLEDNII--------------------VSEVQF-VESSGGGSSAVG 55
D GD +C CG V+ D +I V + Q + S G S+ +G
Sbjct: 26 DYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIG 85
Query: 56 QFVSLDGAGKTPTLGGGFHVNLGKESRA-QTLQNGRRHIHHLGNQLQLNQHCLDTAFNFF 114
+ GA G + N S + + + N + I + +++ L ++ +D N F
Sbjct: 86 KGT---GAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142
Query: 115 KMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLAREL 174
K + +GR + +ACLY+ CR EG P ++ + +++ +G+ F L+ + L
Sbjct: 143 KQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKAL 202
Query: 175 CINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALL 234
+ I ++ RF L + +V M A + ++ + GR P + AA+
Sbjct: 203 ETSVDLITTGDFMSRFCSNLCLPK---QVQMAATHIARKAVELDLVPGRSPISVAAAAIY 259
Query: 235 VAARMHDFRRTVKEVISVVKVCESTLRK 262
+A++ +RT KE+ + V + T+R+
Sbjct: 260 MASQASAEKRTQKEIGDIAGVADVTIRQ 287
>gi|22035562 RNA polymerase III transcription initiation factor BRF2
[Homo sapiens]
Length = 419
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/250 (21%), Positives = 102/250 (40%), Gaps = 42/250 (16%)
Query: 6 CRGCGGTDIELDA--ARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGA 63
C CG T++ D+ ++ VC+ CG V+ + ++ + S +G
Sbjct: 7 CPDCGSTELVEDSHYSQSQLVCSDCGCVVTEGVLTTTF-----------------SDEGN 49
Query: 64 GKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRH-- 121
+ T N E +++ Q G R + L LQL DTA +++ A RH
Sbjct: 50 LREVTYSRSTGEN---EQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAY-RHSG 105
Query: 122 --LTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAP 179
R +K ++ C+ + CR P + + LL ++ V T++ + + L ++ P
Sbjct: 106 IRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVP 165
Query: 180 AIDPCL------YIPRFAHL-------LEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPS 226
++ CL Y F ++ E ++ ++L++ W+ TGR P
Sbjct: 166 SL--CLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPL 223
Query: 227 GLCGAALLVA 236
+ AA +A
Sbjct: 224 PVITAATFLA 233
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 44.3 bits (103), Expect = 4e-04
Identities = 83/369 (22%), Positives = 132/369 (35%), Gaps = 55/369 (14%)
Query: 327 AIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELL 386
A+++ + KA L + S E+ + S E T D++ + R L
Sbjct: 161 ALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPL 220
Query: 387 GG-----APGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDA 441
GG AP +S++ + G P +P+ A S S S S S K
Sbjct: 221 GGRKKKKAPSASDSDSKADSDGAKP------EPVAMARSASSSSSSSSSSDSDVSVKKPP 274
Query: 442 SGDGELDL--------------------SGIDDLEIDRYILNESEARVKAELWMRENAEY 481
G + S D E+DR SE + + E RE
Sbjct: 275 RGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRI----SEWKRRDEARRRELEAR 330
Query: 482 LREQREKEARIAKEKELGIYKEHKPKKS--CKRREPIQASTAREAIEKMLEQKKISSKIN 539
R ++E+E R +E+E KE K ++ R E + S E + + +
Sbjct: 331 RRREQEEELRRLREQE----KEEKERRRERADRGEAERGSGGSSGDELREDDEPVKK--- 383
Query: 540 YSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVG---KRLRPLV 596
RG G G P D++PE + P S S +P G KR+RP
Sbjct: 384 ----RGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQS-SSTEPARKPGQKEKRVRP-E 437
Query: 597 STQPAKKVATGEALLPSSP-TLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPC 655
Q AK V S ++ + + + VE H+ E + D D + C
Sbjct: 438 EKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHS-EIKFALKVDSPDVKRC 496
Query: 656 VSALQMMGS 664
++AL+ +G+
Sbjct: 497 LNALEELGT 505
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 44.3 bits (103), Expect = 4e-04
Identities = 83/369 (22%), Positives = 132/369 (35%), Gaps = 55/369 (14%)
Query: 327 AIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELL 386
A+++ + KA L + S E+ + S E T D++ + R L
Sbjct: 161 ALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPL 220
Query: 387 GG-----APGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDA 441
GG AP +S++ + G P +P+ A S S S S S K
Sbjct: 221 GGRKKKKAPSASDSDSKADSDGAKP------EPVAMARSASSSSSSSSSSDSDVSVKKPP 274
Query: 442 SGDGELDL--------------------SGIDDLEIDRYILNESEARVKAELWMRENAEY 481
G + S D E+DR SE + + E RE
Sbjct: 275 RGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRI----SEWKRRDEARRRELEAR 330
Query: 482 LREQREKEARIAKEKELGIYKEHKPKKS--CKRREPIQASTAREAIEKMLEQKKISSKIN 539
R ++E+E R +E+E KE K ++ R E + S E + + +
Sbjct: 331 RRREQEEELRRLREQE----KEEKERRRERADRGEAERGSGGSSGDELREDDEPVKK--- 383
Query: 540 YSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVG---KRLRPLV 596
RG G G P D++PE + P S S +P G KR+RP
Sbjct: 384 ----RGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQS-SSTEPARKPGQKEKRVRP-E 437
Query: 597 STQPAKKVATGEALLPSSP-TLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPC 655
Q AK V S ++ + + + VE H+ E + D D + C
Sbjct: 438 EKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHS-EIKFALKVDSPDVKRC 496
Query: 656 VSALQMMGS 664
++AL+ +G+
Sbjct: 497 LNALEELGT 505
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 547 SSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVAT 606
S +GGG+ +Q + + + S R TP+ +G G S+ +
Sbjct: 171 SKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTG------FSSNSERGTEA 224
Query: 607 GEALLPSSPTLGAEP----ARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMM 662
G+ P PT A P A + V +++E+DE E +EED E C
Sbjct: 225 GQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGY 284
Query: 663 GSNDYGCDGDEDD 675
S + + DEDD
Sbjct: 285 SSEEAENEEDEDD 297
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 547 SSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVAT 606
S +GGG+ +Q + + + S R TP+ +G G S+ +
Sbjct: 171 SKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTG------FSSNSERGTEA 224
Query: 607 GEALLPSSPTLGAEP----ARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMM 662
G+ P PT A P A + V +++E+DE E +EED E C
Sbjct: 225 GQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGY 284
Query: 663 GSNDYGCDGDEDD 675
S + + DEDD
Sbjct: 285 SSEEAENEEDEDD 297
>gi|83921609 hypothetical protein LOC127254 [Homo sapiens]
Length = 1530
Score = 39.7 bits (91), Expect = 0.009
Identities = 86/372 (23%), Positives = 131/372 (35%), Gaps = 82/372 (22%)
Query: 331 ELENSRPKAKGGL---ASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLG 387
E E SR + G SLAK+ + LC +ED E EE+ A +D +E+L
Sbjct: 1000 EAEASRMQVSEGSPEEGSLAKE-------AFLC-KEDVEGEEMVTEAEANREDDRKEIL- 1050
Query: 388 GAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGEL 447
P + A RP SL +DS RE ++ ++ + + E
Sbjct: 1051 --PKELDLARERRKAERPKT------------SLRKTDSEREEVTRANALKDEDAFKEEQ 1096
Query: 448 DLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEK---ELGIYKEH 504
L + E+E V+AE + + E EA + + G+ E
Sbjct: 1097 KLKAEE---------GETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGED 1147
Query: 505 KPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHS 564
K++ + A EK LE + L GGG E EH
Sbjct: 1148 SLKETV-----VPIFEATPGFEKSLEN-----------ITALRKEGGGERLSEARDTEHK 1191
Query: 565 ASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSS---PTLGAEP 621
+LS R A + G G+ +PA KV E L+P++ L A+
Sbjct: 1192 -DREELSSRENRALKEGH---RQDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKD 1247
Query: 622 --------------------ARPQAVLVESGPVSYHA-DEEADEEEPDEEDGEPCVSALQ 660
R Q + E P+ EEA +E+P+EE+ + C +
Sbjct: 1248 HDSCAGLEGRAEGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETE 1307
Query: 661 MMGSNDYGCDGD 672
M + DGD
Sbjct: 1308 AMQDRNSEGDGD 1319
>gi|16933557 dachsous 1 precursor [Homo sapiens]
Length = 3298
Score = 39.3 bits (90), Expect = 0.012
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 17/120 (14%)
Query: 534 ISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPA------SRSGADPVTS 587
++S++ +++L AGGG D H R L PA +R G P +
Sbjct: 925 VNSRVTFTLL-----AGGGGAFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRT 979
Query: 588 VGKRLRPLVSTQPAKKVA------TGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEE 641
RLR +V + +A T LPS T G + + QA + GP++YH E
Sbjct: 980 SHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGGPITYHLAAE 1039
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 38.9 bits (89), Expect = 0.016
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 286 EEECDPPSYTAGQRKLRMKQ---LEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGG 342
E +P +T QR+L KQ ++Q + K+L+E+E ++ ++ LE R +
Sbjct: 605 ETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYESK 664
Query: 343 LASLAKDGSTEDTASSLCGEEDTEDE 368
L +L K T A+ EE+ E+E
Sbjct: 665 LQALQKQVETRSLAAETTEEEEEEEE 690
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 38.5 bits (88), Expect = 0.021
Identities = 94/423 (22%), Positives = 161/423 (38%), Gaps = 70/423 (16%)
Query: 222 GRRPS-GLCGAA--------LLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPT 272
GRRPS GL GA+ + R+ +E ++ + C ST E ED P+
Sbjct: 650 GRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE--NLKEECSST-ESTQQEHEDAPS 706
Query: 273 SQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIEL 332
++L + + LEEE Q K+R+K+LEQ L + E E E + Q E E
Sbjct: 707 TKLQGEV---LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAER 763
Query: 333 ENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEA--AASHLNKDLYRELLGGAP 390
+ + K A D E + G + D+E EA + L +DL + L
Sbjct: 764 ALLQKEQK------AVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQL---E 814
Query: 391 GSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLS 450
S E G+ G+ S E + S + + +
Sbjct: 815 RESRVEEERELAGQ-----------------GLLRSKAELLRSIAKRKERLA-------- 849
Query: 451 GIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKE-LGIYKEHKPKKS 509
IL+ +++A+ ++E+ R++ + KEKE L + + +
Sbjct: 850 ----------ILDSQAGQIRAQA-VQESERLARDKNASLQLLQKEKEKLTVLERRYHSLT 898
Query: 510 CKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARK 569
R P ST +E +EK+L + ++ GL + + P + ++R+
Sbjct: 899 GGRPFPKTTSTLKE-MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQ 957
Query: 570 LSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLV 629
L R+ P+ R PL P+ ++ + S TLG P+ A+L
Sbjct: 958 LQVYRSKMDGEATSPLPRT--RSGPL----PSSSGSSSSSSQLSVATLGRSPSPKSALLT 1011
Query: 630 ESG 632
++G
Sbjct: 1012 QNG 1014
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 38.5 bits (88), Expect = 0.021
Identities = 94/423 (22%), Positives = 161/423 (38%), Gaps = 70/423 (16%)
Query: 222 GRRPS-GLCGAA--------LLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPT 272
GRRPS GL GA+ + R+ +E ++ + C ST E ED P+
Sbjct: 650 GRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE--NLKEECSST-ESTQQEHEDAPS 706
Query: 273 SQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIEL 332
++L + + LEEE Q K+R+K+LEQ L + E E E + Q E E
Sbjct: 707 TKLQGEV---LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAER 763
Query: 333 ENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEA--AASHLNKDLYRELLGGAP 390
+ + K A D E + G + D+E EA + L +DL + L
Sbjct: 764 ALLQKEQK------AVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQL---E 814
Query: 391 GSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLS 450
S E G+ G+ S E + S + + +
Sbjct: 815 RESRVEEERELAGQ-----------------GLLRSKAELLRSIAKRKERLA-------- 849
Query: 451 GIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKE-LGIYKEHKPKKS 509
IL+ +++A+ ++E+ R++ + KEKE L + + +
Sbjct: 850 ----------ILDSQAGQIRAQA-VQESERLARDKNASLQLLQKEKEKLTVLERRYHSLT 898
Query: 510 CKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARK 569
R P ST +E +EK+L + ++ GL + + P + ++R+
Sbjct: 899 GGRPFPKTTSTLKE-MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQ 957
Query: 570 LSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLV 629
L R+ P+ R PL P+ ++ + S TLG P+ A+L
Sbjct: 958 LQVYRSKMDGEATSPLPRT--RSGPL----PSSSGSSSSSSQLSVATLGRSPSPKSALLT 1011
Query: 630 ESG 632
++G
Sbjct: 1012 QNG 1014
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 38.5 bits (88), Expect = 0.021
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 23/208 (11%)
Query: 464 ESEARVKAELWMRENAEYLREQREKEARI-AKEKELGIYKEHKPKKSCKRREPIQASTAR 522
+ ARVK + E + RE+++K R ++K + +EH ++ R E ++ R
Sbjct: 108 KKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS-RRERDRLEQLERKRER 166
Query: 523 EAIEKMLEQKKISSKINYSVLRG------LSSAGGGSPH----REDAQPEHSASARKLSR 572
E KM EQ+K + R + S H RED + AS S
Sbjct: 167 E--RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 224
Query: 573 RRTPASR----SGADPVTSVGKRLRPLVS-----TQPAKKVATGEALLPSSPTLGAEPAR 623
R P R G PV R L+S + +K ++ E+ S + E
Sbjct: 225 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 284
Query: 624 PQAVLVESGPVSYHADEEADEEEPDEED 651
+ E G S ++EE +EEE +EE+
Sbjct: 285 EEEEEEEEGSTSEESEEEEEEEEEEEEE 312
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 38.5 bits (88), Expect = 0.021
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 23/208 (11%)
Query: 464 ESEARVKAELWMRENAEYLREQREKEARI-AKEKELGIYKEHKPKKSCKRREPIQASTAR 522
+ ARVK + E + RE+++K R ++K + +EH ++ R E ++ R
Sbjct: 74 KKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS-RRERDRLEQLERKRER 132
Query: 523 EAIEKMLEQKKISSKINYSVLRG------LSSAGGGSPH----REDAQPEHSASARKLSR 572
E KM EQ+K + R + S H RED + AS S
Sbjct: 133 E--RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 190
Query: 573 RRTPASR----SGADPVTSVGKRLRPLVS-----TQPAKKVATGEALLPSSPTLGAEPAR 623
R P R G PV R L+S + +K ++ E+ S + E
Sbjct: 191 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 250
Query: 624 PQAVLVESGPVSYHADEEADEEEPDEED 651
+ E G S ++EE +EEE +EE+
Sbjct: 251 EEEEEEEEGSTSEESEEEEEEEEEEEEE 278
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 38.1 bits (87), Expect = 0.027
Identities = 53/205 (25%), Positives = 83/205 (40%), Gaps = 23/205 (11%)
Query: 467 ARVKAELWMRENAEYLREQREKEARI-AKEKELGIYKEHKPKKSCKRREPIQASTAREAI 525
ARVK + E + RE+++K R ++K + +EH ++ R E ++ RE
Sbjct: 88 ARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS-RRERDRLEQLERKRERE-- 144
Query: 526 EKMLEQKKISSKINYSVLRG------LSSAGGGSPH----REDAQPEHSASARKLSRRRT 575
KM EQ+K + R + S H RED + AS S R
Sbjct: 145 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 204
Query: 576 PASR----SGADPVTSVGKRLRPLVS-----TQPAKKVATGEALLPSSPTLGAEPARPQA 626
P R G PV R L+S + +K ++ E+ S + E +
Sbjct: 205 PRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 264
Query: 627 VLVESGPVSYHADEEADEEEPDEED 651
E G S ++EE +EEE +EE+
Sbjct: 265 EEEEEGSTSEESEEEEEEEEEEEEE 289
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 38.1 bits (87), Expect = 0.027
Identities = 53/205 (25%), Positives = 83/205 (40%), Gaps = 23/205 (11%)
Query: 467 ARVKAELWMRENAEYLREQREKEARI-AKEKELGIYKEHKPKKSCKRREPIQASTAREAI 525
ARVK + E + RE+++K R ++K + +EH ++ R E ++ RE
Sbjct: 122 ARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS-RRERDRLEQLERKRERE-- 178
Query: 526 EKMLEQKKISSKINYSVLRG------LSSAGGGSPH----REDAQPEHSASARKLSRRRT 575
KM EQ+K + R + S H RED + AS S R
Sbjct: 179 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 238
Query: 576 PASR----SGADPVTSVGKRLRPLVS-----TQPAKKVATGEALLPSSPTLGAEPARPQA 626
P R G PV R L+S + +K ++ E+ S + E +
Sbjct: 239 PRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 298
Query: 627 VLVESGPVSYHADEEADEEEPDEED 651
E G S ++EE +EEE +EE+
Sbjct: 299 EEEEEGSTSEESEEEEEEEEEEEEE 323
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 37.7 bits (86), Expect = 0.035
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 281 MKIDLEEECDPPSYTAGQRKLRMK--QLEQVLSKKLEEVEGEISSYQD---AIEIELENS 335
MK +L+ E + T +LR K +Q + K E E E+ QD A ++LE S
Sbjct: 755 MKEELQREAEE-KLTLMLLELREKAESEKQTIINKFELREAEMRQLQDQQAAQILDLERS 813
Query: 336 RPKAKGGLASLAKDGSTEDTAS-SLCGEEDTEDEELEAAASHLNKDLYRELL 386
+ +G L L +D +++D S CG E ++ E AA H+ +D +L+
Sbjct: 814 LTEQQGRLQQLEQDLTSDDALHCSQCGREPPTAQDGELAALHVKEDCALQLM 865
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 37.7 bits (86), Expect = 0.035
Identities = 54/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 464 ESEARVKAELWMRENAEYLREQREKEARI-AKEKELGIYKEHKPKKS-----CKRREPI- 516
+ ARVK + E + RE+++K R ++K + +EH ++ C R+ +
Sbjct: 108 KKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLE 167
Query: 517 QASTAREAIEKMLEQKKISSKINYSVLRG------LSSAGGGSPH----REDAQPEHSAS 566
Q RE KM EQ+K + R + S H RED + AS
Sbjct: 168 QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS 227
Query: 567 ARKLSRRRTPASR----SGADPVTSVGKRLRPLVS-----TQPAKKVATGEALLPSSPTL 617
S R P R G PV R L+S + +K ++ E+ S +
Sbjct: 228 HWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 287
Query: 618 GAEPARPQAVLVESGPVSYHADEEADEEEPDEED 651
E + E G S ++EE +EEE +EE+
Sbjct: 288 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 37.4 bits (85), Expect = 0.046
Identities = 35/120 (29%), Positives = 46/120 (38%), Gaps = 11/120 (9%)
Query: 331 ELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAP 390
EL P G S A+ G E EE+ E+ E EA A+ L L GG+
Sbjct: 13 ELSRLSPLPPGSPGSAAR-GRAEPPEEEEEEEEEEEEAEAEAVAALL-------LNGGSG 64
Query: 391 GSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLS 450
G G GG + +P P +AS D E + D +SG GE + S
Sbjct: 65 GGGGGGGGGVGGGEAETMS---EPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESS 121
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 37.4 bits (85), Expect = 0.046
Identities = 35/120 (29%), Positives = 46/120 (38%), Gaps = 11/120 (9%)
Query: 331 ELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAP 390
EL P G S A+ G E EE+ E+ E EA A+ L L GG+
Sbjct: 13 ELSRLSPLPPGSPGSAAR-GRAEPPEEEEEEEEEEEEAEAEAVAALL-------LNGGSG 64
Query: 391 GSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLS 450
G G GG + +P P +AS D E + D +SG GE + S
Sbjct: 65 GGGGGGGGGVGGGEAETMS---EPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESS 121
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 37.0 bits (84), Expect = 0.060
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 13/181 (7%)
Query: 480 EYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKIN 539
E+ R++R + AR +E ++ + K+ +R+ Q RE E+ E++ +
Sbjct: 135 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER--ERRAEERRKE 192
Query: 540 YSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASR----SGADPVTSVGKRLRPL 595
R +S+ RED + AS S R P R G PV R L
Sbjct: 193 REARREVSAHH--RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 250
Query: 596 VS-----TQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEE 650
+S + +K ++ E+ S + E + E G S ++EE +EEE +EE
Sbjct: 251 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 310
Query: 651 D 651
+
Sbjct: 311 E 311
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 37.0 bits (84), Expect = 0.060
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 13/181 (7%)
Query: 480 EYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKIN 539
E+ R++R + AR +E ++ + K+ +R+ Q RE E+ E++ +
Sbjct: 145 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKER--ERRAEERRKE 202
Query: 540 YSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASR----SGADPVTSVGKRLRPL 595
R +S+ RED + AS S R P R G PV R L
Sbjct: 203 REARREVSAHH--RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 260
Query: 596 VS-----TQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEE 650
+S + +K ++ E+ S + E + E G S ++EE +EEE +EE
Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 320
Query: 651 D 651
+
Sbjct: 321 E 321
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 37.0 bits (84), Expect = 0.060
Identities = 80/373 (21%), Positives = 135/373 (36%), Gaps = 43/373 (11%)
Query: 284 DLEEECDPPSYTAGQRKLRMKQLE---QVLSKKLEEVEGEISSYQDAIEIELENSRPKAK 340
++ EE D S G R+ +LE Q +S+K+ E E+ +D ++ L + K
Sbjct: 178 EITEERDILSRQQGDHVARILELEDDIQTISEKVLTKEVELDRLRDTVKA-LTREQEKLL 236
Query: 341 GGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPE 400
G L + D + E+ +EL A++ LLG S+ AA
Sbjct: 237 GQLKEVQADKEQSEAELEPLKEQLRGAQELAASSQQK-----ATLLGEELASAAAARDRT 291
Query: 401 WGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRY 460
+ + + A LG+ +C S+ S + E D EI R
Sbjct: 292 IAELHRSRLEVAEVNGRLAELGLHLKEEKCQWSKERAGLLQSVEAEKDKILKLSAEILRL 351
Query: 461 ILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQAST 520
E R + +++ E A REK++ + + E +RE + +
Sbjct: 352 EKAVQEERTQNQVFKTELA------REKDSSLVQLSE-------------SKRELTELRS 392
Query: 521 AREAIEKMLEQKKISSKINYSVLRGLSSA---GGGSPHREDAQPEHSASARKLSRRRTPA 577
A ++K EQ + + +R L + EDA E +A LS PA
Sbjct: 393 ALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAAVGLS---CPA 449
Query: 578 SRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYH 637
+ + ++ + RL P + P S G A P V+ + P+S H
Sbjct: 450 ALTDSEDESPEDMRLPPYGLCERGD---------PGSSPAGPREASPLVVISQPAPISPH 500
Query: 638 ADEEADEEEPDEE 650
A++ D E
Sbjct: 501 LSGPAEDSSSDSE 513
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 36.6 bits (83), Expect = 0.078
Identities = 101/475 (21%), Positives = 186/475 (39%), Gaps = 61/475 (12%)
Query: 234 LVAARMHDF-------RRTVKEV------ISVVKVCESTLRKRLTEFEDTPTSQLTIDEF 280
L R+HD R T++E + +V L++++ E+E T +Q E
Sbjct: 103 LKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQA---ET 159
Query: 281 MKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAK 340
+ ++ E++ + +RKL+ Q+ + KLEE E ++ S Q A+E K +
Sbjct: 160 IALEKEQKLQN-DFAEKERKLQETQMST--TSKLEEAEHKVQSLQTALE--------KTR 208
Query: 341 GGLASLAKDGSTEDTASSLCGE---EDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAG 397
L L E TA + E D E A + + RE L A S + A
Sbjct: 209 TELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLAS 268
Query: 398 SPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDP---KDASGDGELDLSGIDD 454
+ + P + ++ L T +SL + + +E +Q + AS + S
Sbjct: 269 QIQ---KAPDVEQAIEVL-TRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQI 324
Query: 455 LEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRRE 514
++++ + ++ + E ++ A+Y E+ +KE I K E + + + K E
Sbjct: 325 SQLEQQLSAKNSTLKQLEEKLKGQADY--EEVKKELNILKSMEFAPSEGAGTQDAAKPLE 382
Query: 515 PIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGG---------GS-----PHREDAQ 560
+ R L+ + + +I+ S L G + G GS P +
Sbjct: 383 VLLLEKNRS-----LQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRN 437
Query: 561 PEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVST-QPAKKVATGEALLPSSPTLGA 619
P AS + + +PA S +S+ PL ST + A L+ S +
Sbjct: 438 PGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAM 497
Query: 620 EPARPQAVLVESGPVSYH--ADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGD 672
+ A +++ +GP S + + + ++ PD P S + GS G + D
Sbjct: 498 QEAGSTSMIFSTGPYSTNSISSQSPLQQSPDVNGMAPSPSQSESAGSVSEGEEMD 552
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 36.6 bits (83), Expect = 0.078
Identities = 53/232 (22%), Positives = 94/232 (40%), Gaps = 34/232 (14%)
Query: 462 LNESEARVKAELWMR-ENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQAST 520
L E E R K E R + E L +R++E R+ +EK +E K +K +R+E ++
Sbjct: 351 LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEK-----RERKKQKEKERKERLKKEG 405
Query: 521 AREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRS 580
K+L + + ++ L A G +D+ P+ R++ P
Sbjct: 406 ------KLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLE 459
Query: 581 GADPVTS-------------VGKRLRPLVSTQPAKKVATGEALLPSSPTLGA----EPAR 623
+ S V ++ +P ++ T +A L + + E
Sbjct: 460 SKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVE 519
Query: 624 PQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDD 675
V +E V + +EE +EEE +EED E + G ++ G +GDE+D
Sbjct: 520 GNKVHIE---VKENPEEEEEEEEEEEED-EESEEEEEEEGESE-GSEGDEED 566
>gi|24431975 hypothetical protein LOC26148 [Homo sapiens]
Length = 1247
Score = 36.6 bits (83), Expect = 0.078
Identities = 61/240 (25%), Positives = 104/240 (43%), Gaps = 33/240 (13%)
Query: 292 PSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGS 351
P TAGQ L ++LE + K++E I S A + + E ++ + G + + + +
Sbjct: 623 PITTAGQ-PLPGERLEIYVQSKMDEKNAHIPSESIACKRDPEQAKEEP-GHIPTQHVEEA 680
Query: 352 TEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSL 411
+ + +D+E +A S L + GS +AA +P+ RP L S
Sbjct: 681 VNEVDNE---NTQQKDDESDAPCSSLGLS--------SSGSGDAARAPKSVPRPKRLTSS 729
Query: 412 LDPLPTAASLGISDSIRECISSQSSD-----PKD--ASGDGE-LDLSGIDDLEIDRYILN 463
L A SLG D+ + +++ PK+ AS G+ LD +D + ++
Sbjct: 730 TYNLRHAHSLGSLDASKVTSEKEAAQVNPIMPKENGASESGDPLDEDDVDTVVDEQPKFM 789
Query: 464 ESEARVK-AELWMRENAEYLREQR-----EKE------ARIAKEKELGIYKEHKPKKSCK 511
E A + EL NA+Y++ Q+ EKE AR +K I+K K + C+
Sbjct: 790 EWCAEEENQELIANFNAQYMKVQKGWIQLEKEGQPTPRARNKSDKLKEIWKSKKRSRKCR 849
>gi|30581160 ganglioside-induced differentiation-associated protein
1-like 1 [Homo sapiens]
Length = 367
Score = 36.6 bits (83), Expect = 0.078
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 279 EFMKIDLEEECD-PPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRP 337
+ MK+D EEE Y + Q+KL K LE L+++ GE++ D IE ELE +
Sbjct: 191 DLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKL 250
Query: 338 KAKGGLASLAKDGSTEDTASSLCG 361
+ +G L G A L G
Sbjct: 251 ENEGQKCELWLCGCAFTLADVLLG 274
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 36.2 bits (82), Expect = 0.10
Identities = 73/377 (19%), Positives = 135/377 (35%), Gaps = 30/377 (7%)
Query: 279 EFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPK 338
E K ++ E P K K E+ S EE + + E S K
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA--KSPEK 721
Query: 339 AKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGS 398
AK + AK T + A S EE E+ ++ D+ S EA
Sbjct: 722 AKSPVKEEAK---TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK---------SPEAKTP 769
Query: 399 PEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEID 458
+ R PA D P A + + ++ ++S +DA E ++ ++++
Sbjct: 770 AKEEARSPA-----DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEVKSP 823
Query: 459 -RYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQ 517
+ E +VK E + + +E + +K++E + KPK K+ ++
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 518 ASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKL----SRR 573
E +E KK ++ V A +EDA+P+ K ++
Sbjct: 884 KPK-----ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA 938
Query: 574 RTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGP 633
+ P+ + K + + +P +K T TL EP++P+A E
Sbjct: 939 KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998
Query: 634 VSYHADEEADEEEPDEE 650
+ D + E+ +++
Sbjct: 999 STDQKDSKPPEKATEDK 1015
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 36.2 bits (82), Expect = 0.10
Identities = 73/302 (24%), Positives = 120/302 (39%), Gaps = 66/302 (21%)
Query: 303 MKQLEQVLSKKLEEVEGE--------ISSYQDA-------------IEIELENSRPK-AK 340
M+Q QV +KL+E EGE + S ++A +E++LE +R + A+
Sbjct: 1341 MRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAE 1400
Query: 341 GGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYREL-LGGAP--------- 390
GL A +G + + L E + EA L L R L LG AP
Sbjct: 1401 LGLRLSAAEGRAQGLEAELARVE-VQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPG 1459
Query: 391 ---------GSSEAAGSPEW-----GGRPPALGSLLDPL-----PTAASLGISDSIRECI 431
GS E SP G +PP+ G P P A + + ++E
Sbjct: 1460 SPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELR 1519
Query: 432 SSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEAR 491
S+Q + + L+ + ++E +R A +A + AE +R + R
Sbjct: 1520 SAQRERDELRTQTSALNRQ-LAEMEAER-----DSATSRARQLQKAVAESEEARRSVDGR 1573
Query: 492 IA-KEKELGIYKEHKPKKSCKRREPI-QASTAREAI-----EKMLEQKKISS-KINYSVL 543
++ + EL + +E + +RR + Q +T ++ E Q+KIS K N + L
Sbjct: 1574 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1633
Query: 544 RG 545
G
Sbjct: 1634 EG 1635
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,570,704
Number of Sequences: 37866
Number of extensions: 1375619
Number of successful extensions: 8074
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 281
Number of HSP's that attempted gapping in prelim test: 7425
Number of HSP's gapped (non-prelim): 804
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.