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Search of human proteins with 194353946
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194353946 homeobox D12 [Homo sapiens]
(270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194353946 homeobox D12 [Homo sapiens] 549 e-157
gi|27804315 homeobox C12 [Homo sapiens] 184 9e-47
gi|23510368 homeobox D11 [Homo sapiens] 103 1e-22
gi|7657166 homeobox C11 [Homo sapiens] 87 2e-17
gi|5031759 homeobox A11 [Homo sapiens] 87 2e-17
gi|24497554 homeobox A13 [Homo sapiens] 86 4e-17
gi|116734702 homeobox D13 [Homo sapiens] 84 1e-16
gi|194363768 homeobox D9 [Homo sapiens] 83 2e-16
gi|24497536 homeobox C13 [Homo sapiens] 82 6e-16
gi|15029508 homeobox B9 [Homo sapiens] 81 8e-16
gi|24497533 homeobox C10 [Homo sapiens] 80 2e-15
gi|23510366 homeobox D10 [Homo sapiens] 79 3e-15
gi|23097236 homeobox A9 [Homo sapiens] 79 5e-15
gi|148613882 homeobox A4 [Homo sapiens] 78 7e-15
gi|15029506 homeobox D8 [Homo sapiens] 78 9e-15
gi|89257348 homeo box HB9 [Homo sapiens] 78 9e-15
gi|24497551 homeobox A10 isoform b [Homo sapiens] 77 1e-14
gi|182765442 homeobox A10 isoform a [Homo sapiens] 77 1e-14
gi|62865866 homeobox B13 [Homo sapiens] 77 2e-14
gi|24497547 homeobox C9 [Homo sapiens] 76 4e-14
gi|13375632 homeobox D1 [Homo sapiens] 74 1e-13
gi|24497517 homeobox A5 [Homo sapiens] 74 1e-13
gi|24497513 homeobox A3 isoform a [Homo sapiens] 74 1e-13
gi|13562112 homeobox A3 isoform a [Homo sapiens] 74 1e-13
gi|23397672 homeobox D4 [Homo sapiens] 74 2e-13
gi|4504465 homeobox B2 [Homo sapiens] 73 2e-13
gi|12056969 homeobox C8 [Homo sapiens] 72 4e-13
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 72 5e-13
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 72 5e-13
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 72 7e-13
>gi|194353946 homeobox D12 [Homo sapiens]
Length = 270
Score = 549 bits (1415), Expect = e-157
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAP 60
MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAP
Sbjct: 1 MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAP 60
Query: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120
AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA
Sbjct: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120
Query: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG 180
PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG
Sbjct: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG 180
Query: 181 VASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLN 240
VASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLN
Sbjct: 181 VASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLN 240
Query: 241 LSDQQVKIWFQNRRMKKKRVVLREQALALY 270
LSDQQVKIWFQNRRMKKKRVVLREQALALY
Sbjct: 241 LSDQQVKIWFQNRRMKKKRVVLREQALALY 270
>gi|27804315 homeobox C12 [Homo sapiens]
Length = 282
Score = 184 bits (466), Expect = 9e-47
Identities = 128/294 (43%), Positives = 159/294 (54%), Gaps = 36/294 (12%)
Query: 1 MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAP 60
M E +L G+VG L+N+ + D+FYF N R +G QL LP +SYPR C+
Sbjct: 1 MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRASGAQLPGLPSLSYPR-------RDNVCSL 53
Query: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPP---TAKDGPEEQAKFYAPEAAAGP-------E 110
+ P+ A G+ QPYL P+ L PP T + E K Y E A E
Sbjct: 54 SWPS-AEPCNGYPQPYLGS--PVSLNPPFGRTCELARVEDGKGYYREPCAEGGGGGLKRE 110
Query: 111 ERGRTRPSFAPESSLAPAVAALKAA---KYDYA--GVGRATPGSTTLLQGAPCAPGFKDD 165
ERGR P P ++L P + A KYDYA G G G P + D
Sbjct: 111 ERGRD-PGAGPGAALLPLEPSGPPALGFKYDYAAGGGGGDGGGGAGPPHDPPSCQSLESD 169
Query: 166 TKGPLNLNMTVQAAGVA---SCLRPSLP------DGLPWGAAPGRARKKRKPYTKQQIAE 216
+ L LN + AG S + P P G PW R+RKKRKPY+K Q+AE
Sbjct: 170 SSSSL-LNEGNKGAGAGDPGSLVSPLNPGGGLSASGAPWYPINSRSRKKRKPYSKLQLAE 228
Query: 217 LENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY 270
LE EFLVNEFI RQ+R+ELS+RLNLSDQQVKIWFQNRRMKKKR++LREQAL+ +
Sbjct: 229 LEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF 282
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 103 bits (258), Expect = 1e-22
Identities = 89/232 (38%), Positives = 110/232 (47%), Gaps = 39/232 (16%)
Query: 35 QLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGP 94
Q LPP L A P AP P G G + + + G G+ P
Sbjct: 126 QRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPA---GAASNFYSAVGRNGILP------- 175
Query: 95 EEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVG------RATPG 148
+ +FY EAA GP G P P + P AA K AG G +ATPG
Sbjct: 176 QGFDQFY--EAAPGPPFAGPQPPP--PPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPG 231
Query: 149 STTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKP 208
S +GA A G D +GP G A + S AP R+RKKR P
Sbjct: 232 SEP--KGA--AEGSGGDGEGP---------PGEAGAEKSSS------AVAPQRSRKKRCP 272
Query: 209 YTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
YTK QI ELE EF N +IN++KR +LS LNL+D+QVKIWFQNRRMK+K++
Sbjct: 273 YTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 324
>gi|7657166 homeobox C11 [Homo sapiens]
Length = 304
Score = 87.0 bits (214), Expect = 2e-17
Identities = 43/67 (64%), Positives = 53/67 (79%), Gaps = 2/67 (2%)
Query: 196 GAAPG--RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNR 253
GAAP R RKKR PY+K QI ELE EF N +IN++KR +LS LNL+D+QVKIWFQNR
Sbjct: 224 GAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNR 283
Query: 254 RMKKKRV 260
RMK+K++
Sbjct: 284 RMKEKKL 290
>gi|5031759 homeobox A11 [Homo sapiens]
Length = 313
Score = 86.7 bits (213), Expect = 2e-17
Identities = 40/65 (61%), Positives = 52/65 (80%)
Query: 196 GAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRM 255
G++ R RKKR PYTK QI ELE EF + +IN++KR +LS LNL+D+QVKIWFQNRRM
Sbjct: 235 GSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRM 294
Query: 256 KKKRV 260
K+K++
Sbjct: 295 KEKKI 299
>gi|24497554 homeobox A13 [Homo sapiens]
Length = 388
Score = 85.5 bits (210), Expect = 4e-17
Identities = 61/204 (29%), Positives = 98/204 (48%), Gaps = 20/204 (9%)
Query: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120
AQPA A A F+ Y+ +GP + + ++ FY AAGP + P +
Sbjct: 195 AQPASAAAAAAFADKYMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQPMPGYL 250
Query: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG 180
+ + P + ++++ G+ + L G + P +L
Sbjct: 251 -DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHL-------- 301
Query: 181 VASCLRPSLPDGLPW---GAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSN 237
+ +LPD + ++ R RKKR PYTK Q+ ELE E+ N+FI + KR+ +S
Sbjct: 302 ----WKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISA 357
Query: 238 RLNLSDQQVKIWFQNRRMKKKRVV 261
NLS++QV IWFQNRR+K+K+V+
Sbjct: 358 TTNLSERQVTIWFQNRRVKEKKVI 381
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/170 (30%), Positives = 64/170 (37%), Gaps = 17/170 (10%)
Query: 29 LRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSG---PLGL 85
L NGG L A GA AA A+ A A AGA GGF P A +G +
Sbjct: 19 LYDNGGGLVADELNKNMEGA---AAAAAAAAAAAAAGAGG-GGFPHPAAAAAGGNFSVAA 74
Query: 86 QPPTAKDGPEEQAKFY-------APEAAAGPEER-GRTRPSFAPESSLAPAVAALKAAKY 137
A Q + AP AA+ G PS A ++ A A AA AA
Sbjct: 75 AAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAAS 134
Query: 138 DYAGVGRATP-GSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLR 186
G G A P G+ Q +PC+ + GP L +G C R
Sbjct: 135 SSGGPGPAGPAGAEAAKQCSPCSAA-AQSSSGPAALPYGYFGSGYYPCAR 183
>gi|116734702 homeobox D13 [Homo sapiens]
Length = 343
Score = 84.0 bits (206), Expect = 1e-16
Identities = 37/61 (60%), Positives = 49/61 (80%)
Query: 201 RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
R RKKR PYTK Q+ ELENE+ +N+FIN+ KR+ +S NLS++QV IWFQNRR+K K++
Sbjct: 275 RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKI 334
Query: 261 V 261
V
Sbjct: 335 V 335
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 83.2 bits (204), Expect = 2e-16
Identities = 68/210 (32%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 57 SCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTR 116
S P+ PA +G A P T+ + E + E +G +
Sbjct: 146 SPGPSGPANGRHYG-IKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSG 204
Query: 117 PSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCA----PG--FKDDTKGPL 170
P F+ S L AA AG+G AT G+ + + C+ PG K++ K
Sbjct: 205 PEFSCNSFLQEKAAAATGGTGPGAGIGAAT-GTGGSSEPSACSDHPIPGCSLKEEEKQ-- 261
Query: 171 NLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQ 230
+ L P+ P W A RKKR PYTK Q ELE EFL N ++ R
Sbjct: 262 ------HSQPQQQQLDPNNP-AANWIHARS-TRKKRCPYTKYQTLELEKEFLFNMYLTRD 313
Query: 231 KRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
+R E++ LNL+++QVKIWFQNRRMK K++
Sbjct: 314 RRYEVARILNLTERQVKIWFQNRRMKMKKM 343
>gi|24497536 homeobox C13 [Homo sapiens]
Length = 330
Score = 81.6 bits (200), Expect = 6e-16
Identities = 74/259 (28%), Positives = 118/259 (45%), Gaps = 43/259 (16%)
Query: 41 PISYPRGAL------PWAATPASCAPAQPAGATAFGGFSQPYLAG------SGPLGLQPP 88
P+ P+GA+ P AA + PA P ++A G+ P+ S + LQ
Sbjct: 84 PLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQK 143
Query: 89 TAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPG 148
P ++ Y + A P G S A E + P+ A+ A Y V
Sbjct: 144 PCAYHPGDK---YPEPSGALP---GDDLSSRAKEFAFYPSFASSYQAMPGYLDV------ 191
Query: 149 STTLLQGAPCAPGFKDDTKGPLN--------------LNMTVQAAGVASCLRPSLPDGLP 194
+++ G P + D P+ + + + + A + PD +P
Sbjct: 192 --SVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVP 249
Query: 195 WG---AAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQ 251
++ R RKKR PYTK Q+ ELE E+ ++FI ++KR+ +S NLS++QV IWFQ
Sbjct: 250 LQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQ 309
Query: 252 NRRMKKKRVVLREQALALY 270
NRR+K+K+VV + +A L+
Sbjct: 310 NRRVKEKKVVSKSKAPHLH 328
>gi|15029508 homeobox B9 [Homo sapiens]
Length = 250
Score = 81.3 bits (199), Expect = 8e-16
Identities = 73/258 (28%), Positives = 110/258 (42%), Gaps = 33/258 (12%)
Query: 11 YVGSLLNLQS--------PDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQ 62
YV S+++ +S P Y S+ +P + P S+ A + A S AP
Sbjct: 11 YVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGA---SWAPLS 67
Query: 63 PAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPE 122
P + + PY+ P G+ P ++ + + A G G+ + + E
Sbjct: 68 PHASGSLPSVYHPYIQ---PQGVPPAESR-----YLRTWLEPAPRGEAAPGQGQAAVKAE 119
Query: 123 SSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVA 182
L LK +Y+ + G +L PG+ D+ G
Sbjct: 120 PLLGAPGELLKQGTPEYSL--ETSAGREAVLSNQ--RPGYGDNKI----------CEGSE 165
Query: 183 SCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLS 242
RP + +RKKR PYTK Q ELE EFL N ++ R +R E++ LNLS
Sbjct: 166 DKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS 225
Query: 243 DQQVKIWFQNRRMKKKRV 260
++QVKIWFQNRRMK K++
Sbjct: 226 ERQVKIWFQNRRMKMKKM 243
>gi|24497533 homeobox C10 [Homo sapiens]
Length = 342
Score = 79.7 bits (195), Expect = 2e-15
Identities = 36/58 (62%), Positives = 46/58 (79%)
Query: 203 RKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
RKKR PYTK Q ELE EFL N ++ R++R E+S +NL+D+QVKIWFQNRRMK K++
Sbjct: 269 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKM 326
>gi|23510366 homeobox D10 [Homo sapiens]
Length = 340
Score = 79.3 bits (194), Expect = 3e-15
Identities = 36/58 (62%), Positives = 46/58 (79%)
Query: 203 RKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
RKKR PYTK Q ELE EFL N ++ R++R E+S +NL+D+QVKIWFQNRRMK K++
Sbjct: 267 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKM 324
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 78.6 bits (192), Expect = 5e-15
Identities = 63/171 (36%), Positives = 84/171 (49%), Gaps = 14/171 (8%)
Query: 102 APEAAAGPEER---GRTRP-----SFAPESSLAP---AVAALKAAKYDYAGVGRATPGST 150
AP AAA P+ R P SFA S P L A + D + T T
Sbjct: 96 APVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLT 155
Query: 151 TLLQGAPCAPGFKDDTKGPLNLNMTV-QAAGVASCLRPSLPDGLPWGAAPGRARKKRKPY 209
G+P K ++G + N ++ G + P+ P W A RKKR PY
Sbjct: 156 DYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNP-AANWLHARS-TRKKRCPY 213
Query: 210 TKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
TK Q ELE EFL N ++ R +R E++ LNL+++QVKIWFQNRRMK K++
Sbjct: 214 TKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKI 264
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 78.2 bits (191), Expect = 7e-15
Identities = 72/225 (32%), Positives = 97/225 (43%), Gaps = 26/225 (11%)
Query: 40 PPISY--PRGALPWAATPASCAPAQPAGATAFG-GFSQPYLAGSGPLGLQPPTAKDGPEE 96
P SY PR A A A+ PA A TA+ G+ G P QPP GP
Sbjct: 69 PTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAH 128
Query: 97 QAKF-YAPEAAAGPEERGRTRPSFAPES-SLAPAVAALKAAKYDYAGVGRATPGSTTLLQ 154
+ + P + R P AP APA + A G A L
Sbjct: 129 GLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAG-------GSAPACPLLLAD 181
Query: 155 GAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQI 214
+P K+ P + V A + PS G P ++ R YT+QQ+
Sbjct: 182 KSPLGLKGKEPVVYPWMKKIHVSA------VNPSYNGGEP--------KRSRTAYTRQQV 227
Query: 215 AELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
ELE EF N ++ R++R E+++ L LS++QVKIWFQNRRMK K+
Sbjct: 228 LELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKK 272
>gi|15029506 homeobox D8 [Homo sapiens]
Length = 290
Score = 77.8 bits (190), Expect = 9e-15
Identities = 68/218 (31%), Positives = 97/218 (44%), Gaps = 23/218 (10%)
Query: 56 ASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPP--TAKDGPEEQAKFYAPEAAAGPEERG 113
A+ A Q G +A G P A + P PP T G E + + Y P
Sbjct: 46 AAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAY 105
Query: 114 RTRPSFAPESSLAP--------AVAALKAAKYDYAGVGR----ATPGSTTLLQGAPCAPG 161
+ P P P A A Y Y + R T L+Q C
Sbjct: 106 QAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSS 165
Query: 162 FKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEF 221
+ + P +LN + + + +RP AAPGR R+ R+ Y++ Q ELE EF
Sbjct: 166 SGNIGEDPDHLNQSSSPSQMFPWMRPQ--------AAPGR-RRGRQTYSRFQTLELEKEF 216
Query: 222 LVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
L N ++ R++R E+S+ L L+++QVKIWFQNRRMK K+
Sbjct: 217 LFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKK 254
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 77.8 bits (190), Expect = 9e-15
Identities = 72/205 (35%), Positives = 97/205 (47%), Gaps = 29/205 (14%)
Query: 61 AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120
A P A A + AG LGL P A+ G A A A G G
Sbjct: 117 AHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGG----AGLPAQAALYGHPVYGY------ 166
Query: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGA-PCAPGFKDDTK---GPLNLNMTV 176
S A A AAL AG A S +QGA P P D K G L+ +
Sbjct: 167 ---SAAAAAAAL-------AGQHPALSYSYPQVQGAHPAHPA--DPIKLGAGTFQLDQWL 214
Query: 177 QAAGVASCLRPSLPDGLPWGAAP--GRARKKRKPYTKQQIAELENEFLVNEFINRQKRKE 234
+A+ A + P +PD + G+ R+ R +T QQ+ ELE++F +N++++R KR E
Sbjct: 215 RAS-TAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFE 273
Query: 235 LSNRLNLSDQQVKIWFQNRRMKKKR 259
++ L L++ QVKIWFQNRRMK KR
Sbjct: 274 VATSLMLTETQVKIWFQNRRMKWKR 298
>gi|24497551 homeobox A10 isoform b [Homo sapiens]
Length = 94
Score = 77.4 bits (189), Expect = 1e-14
Identities = 35/58 (60%), Positives = 46/58 (79%)
Query: 203 RKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
RKKR PYTK Q ELE EFL N ++ R++R E+S ++L+D+QVKIWFQNRRMK K++
Sbjct: 21 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKM 78
>gi|182765442 homeobox A10 isoform a [Homo sapiens]
Length = 410
Score = 77.4 bits (189), Expect = 1e-14
Identities = 35/58 (60%), Positives = 46/58 (79%)
Query: 203 RKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
RKKR PYTK Q ELE EFL N ++ R++R E+S ++L+D+QVKIWFQNRRMK K++
Sbjct: 337 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKM 394
>gi|62865866 homeobox B13 [Homo sapiens]
Length = 284
Score = 77.0 bits (188), Expect = 2e-14
Identities = 71/244 (29%), Positives = 100/244 (40%), Gaps = 28/244 (11%)
Query: 39 LPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPY-LAGSGPLGLQPPTAKDGPEEQ 97
+P ++Y LP +A P P PY G G + + P Q
Sbjct: 43 MPAVNYAPLDLPGSAEPPKQCHPCPGVPQGTSPAPVPYGYFGGGYYSCRVSRSSLKPCAQ 102
Query: 98 AKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAP 157
A A A P G PS E + P Y V S GAP
Sbjct: 103 AATLAAYPAETPTA-GEEYPSRPTEFAFYPGYPGTYQPMASYLDV------SVVQTLGAP 155
Query: 158 CAPGFKDDTKGPLNLNMTVQAAG----VASCLRPSLPDGLPWGAAPG------------- 200
P + D+ P++ + AG C P G W AA
Sbjct: 156 GEP--RHDSLLPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPPDACAF 213
Query: 201 -RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
R RKKR PY+K Q+ ELE E+ N+FI + KR+++S +LS++Q+ IWFQNRR+K+K+
Sbjct: 214 RRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273
Query: 260 VVLR 263
V+ +
Sbjct: 274 VLAK 277
>gi|24497547 homeobox C9 [Homo sapiens]
Length = 260
Score = 75.9 bits (185), Expect = 4e-14
Identities = 35/58 (60%), Positives = 45/58 (77%)
Query: 203 RKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
RKKR PYTK Q ELE EFL N ++ R +R E++ LNL+++QVKIWFQNRRMK K++
Sbjct: 193 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKM 250
>gi|13375632 homeobox D1 [Homo sapiens]
Length = 328
Score = 74.3 bits (181), Expect = 1e-13
Identities = 65/233 (27%), Positives = 98/233 (42%), Gaps = 29/233 (12%)
Query: 52 AATPASCAPAQPAGAT----AFGGFSQPYLAGSGPLGLQPPTAKDGPE-----EQAKFYA 102
AA P+ PA PA + A ++Q L G+ G P A G + +
Sbjct: 58 AARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDF 117
Query: 103 PEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPG- 161
P + G + +A + + + L + + DYA G P L A PG
Sbjct: 118 PGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGA 177
Query: 162 FKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKK---------------R 206
F+ + P +V A P+ W A KK R
Sbjct: 178 FQTASPAPGTYPKSVSPASGL----PAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIR 233
Query: 207 KPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
++ +Q+ ELE EF N+++ R +R E++N L+L+D QVKIWFQNRRMK+K+
Sbjct: 234 TNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKK 286
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 74.3 bits (181), Expect = 1e-13
Identities = 59/193 (30%), Positives = 89/193 (46%), Gaps = 31/193 (16%)
Query: 93 GPEEQAKFYAPEAAAGPEERGRTRPS---FAPESSLAPAVAALKAAKYDYAGVGR----- 144
G E+A+ YA A+A P E ++P+ +P+ P A + D G+
Sbjct: 65 GSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSN 124
Query: 145 -----ATPGSTTLL--QGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPW-- 195
A GST + +G A G ++D + A S P+ P PW
Sbjct: 125 SSGASADAGSTHISSREGVGTASGAEEDAPAS---SEQASAQSEPSPAPPAQPQIYPWMR 181
Query: 196 ---------GAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQV 246
G G+ + R YT+ Q ELE EF N ++ R++R E+++ L LS++Q+
Sbjct: 182 KLHISHDNIGGPEGK--RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQI 239
Query: 247 KIWFQNRRMKKKR 259
KIWFQNRRMK K+
Sbjct: 240 KIWFQNRRMKWKK 252
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 73.9 bits (180), Expect = 1e-13
Identities = 60/187 (32%), Positives = 81/187 (43%), Gaps = 18/187 (9%)
Query: 73 SQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAAL 132
SQP G PL PP A P Q AP+ A T + P SS +P A
Sbjct: 80 SQPPSLGEPPLHPPPPQAAP-PAPQPPQPAPQPPAP------TPAAPPPPSSASPPQNAS 132
Query: 133 KAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDG 192
A T Q P + +TK T ++ SC P G
Sbjct: 133 NNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTK-----QKTSSSSSGESCAGDKSPPG 187
Query: 193 LPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQN 252
+++ R YT Q+ ELE EF N ++ R +R E++N LNL+++Q+KIWFQN
Sbjct: 188 ------QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 241
Query: 253 RRMKKKR 259
RRMK K+
Sbjct: 242 RRMKYKK 248
Score = 28.9 bits (63), Expect = 4.9
Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 45/141 (31%)
Query: 10 GYVGSLLNL--------QSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPA 61
GY+ S+ +L QSP F +P G LPP SYP A+ SCAP
Sbjct: 275 GYLNSMHSLVNSVPYEPQSPPPFS----KPPQGTYG-LPPASYP-------ASLPSCAPP 322
Query: 62 QP-------AGATA---------------FGGFSQPYLAGSGPL---GLQPPTAKDGPEE 96
P AGA A G + P++ GS P + GP
Sbjct: 323 PPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPAL 382
Query: 97 QAKFYAPEAAAGPEERGRTRP 117
+ P AA+G + G P
Sbjct: 383 FGLTHLPHAASGAMDYGGAGP 403
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 73.9 bits (180), Expect = 1e-13
Identities = 60/187 (32%), Positives = 81/187 (43%), Gaps = 18/187 (9%)
Query: 73 SQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAAL 132
SQP G PL PP A P Q AP+ A T + P SS +P A
Sbjct: 80 SQPPSLGEPPLHPPPPQAAP-PAPQPPQPAPQPPAP------TPAAPPPPSSASPPQNAS 132
Query: 133 KAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDG 192
A T Q P + +TK T ++ SC P G
Sbjct: 133 NNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTK-----QKTSSSSSGESCAGDKSPPG 187
Query: 193 LPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQN 252
+++ R YT Q+ ELE EF N ++ R +R E++N LNL+++Q+KIWFQN
Sbjct: 188 ------QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 241
Query: 253 RRMKKKR 259
RRMK K+
Sbjct: 242 RRMKYKK 248
Score = 28.9 bits (63), Expect = 4.9
Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 45/141 (31%)
Query: 10 GYVGSLLNL--------QSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPA 61
GY+ S+ +L QSP F +P G LPP SYP A+ SCAP
Sbjct: 275 GYLNSMHSLVNSVPYEPQSPPPFS----KPPQGTYG-LPPASYP-------ASLPSCAPP 322
Query: 62 QP-------AGATA---------------FGGFSQPYLAGSGPL---GLQPPTAKDGPEE 96
P AGA A G + P++ GS P + GP
Sbjct: 323 PPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPAL 382
Query: 97 QAKFYAPEAAAGPEERGRTRP 117
+ P AA+G + G P
Sbjct: 383 FGLTHLPHAASGAMDYGGAGP 403
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 73.6 bits (179), Expect = 2e-13
Identities = 63/204 (30%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 56 ASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRT 115
A A QP G F + GSGP A+ +E AA G
Sbjct: 41 AQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPG------- 93
Query: 116 RPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMT 175
P AP AP A L A+ + P T L Q A P K +N N T
Sbjct: 94 EPCPAPP---APPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYT 150
Query: 176 VQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKEL 235
G ++ R YT+QQ+ ELE EF N ++ R++R E+
Sbjct: 151 -----------------------GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEI 187
Query: 236 SNRLNLSDQQVKIWFQNRRMKKKR 259
++ L LS++Q+KIWFQNRRMK K+
Sbjct: 188 AHTLCLSERQIKIWFQNRRMKWKK 211
>gi|4504465 homeobox B2 [Homo sapiens]
Length = 356
Score = 73.2 bits (178), Expect = 2e-13
Identities = 57/158 (36%), Positives = 76/158 (48%), Gaps = 20/158 (12%)
Query: 114 RTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGF----------- 162
+T PS P +S + K A+ A P L AP AP F
Sbjct: 51 QTFPSLQPGASTLQRPRSQKRAEDGPA----LPPPPPPPLPAAPPAPEFPWMKEKKSAKK 106
Query: 163 -KDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEF 221
P V A+GV S P+ GLP A G AR+ R YT Q+ ELE EF
Sbjct: 107 PSQSATSPSPAASAVPASGVGS---PADGLGLP-EAGGGGARRLRTAYTNTQLLELEKEF 162
Query: 222 LVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
N+++ R +R E++ L+L+++QVK+WFQNRRMK KR
Sbjct: 163 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200
>gi|12056969 homeobox C8 [Homo sapiens]
Length = 242
Score = 72.4 bits (176), Expect = 4e-13
Identities = 43/97 (44%), Positives = 58/97 (59%), Gaps = 5/97 (5%)
Query: 165 DTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGA--APGRARKKRKPYTKQQIAELENEFL 222
D K N N + + PSL PW APGR R R+ Y++ Q ELE EFL
Sbjct: 113 DCKSSANTNSSEGQGHLNQNSSPSLM--FPWMRPHAPGR-RSGRQTYSRYQTLELEKEFL 169
Query: 223 VNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
N ++ R++R E+S+ L L+++QVKIWFQNRRMK K+
Sbjct: 170 FNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK 206
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 72.0 bits (175), Expect = 5e-13
Identities = 52/164 (31%), Positives = 76/164 (46%), Gaps = 25/164 (15%)
Query: 106 AAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPG-FKD 164
+ GP E G + P SS +G +TP GA CAPG +
Sbjct: 114 SGGPPELGSSPPVLCSNSS----------------SLGSSTP------TGAACAPGDYGR 151
Query: 165 DTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVN 224
P ++ G +G + RK+R +TK+QI ELE EF +
Sbjct: 152 QALSPAEAEK--RSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHH 209
Query: 225 EFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALA 268
++ R +R E++ L+L+++QVK+WFQNRRMK KRV +Q A
Sbjct: 210 NYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAA 253
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 72.0 bits (175), Expect = 5e-13
Identities = 79/277 (28%), Positives = 110/277 (39%), Gaps = 68/277 (24%)
Query: 41 PISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSG-------------PLGLQP 87
P+ P+ P A PA P P + A G + + AG G P +P
Sbjct: 54 PLVLPQALAP-APLPAGLPPLAPLASFA-GRLTNTFCAGLGQAVPSMVALTTALPSFAEP 111
Query: 88 PTAKDGPEEQAKFYAPEAAAG----PEERGRTRPSFAPESSLAPA--------------- 128
P A GP+E A A AA PE GR L PA
Sbjct: 112 PDAFYGPQELAAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHF 171
Query: 129 -----------------VAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLN 171
L+A+ D AG + GS G GF D + G
Sbjct: 172 SETFPSLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSG----GDSEDDGFLDSSAGGPG 227
Query: 172 LNMTVQAAGVASCLRPSLPDGLPWGA-------APG-RARKKRKPYTKQQIAELENEFLV 223
+ G L+ SL G GA APG ++R++R +T +Q+ ELE EF
Sbjct: 228 ALL-----GPKPKLKGSLGTGAEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHC 282
Query: 224 NEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
++++ +R ++++ L LS+ QVKIWFQNRR K KR+
Sbjct: 283 KKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRI 319
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 71.6 bits (174), Expect = 7e-13
Identities = 33/68 (48%), Positives = 48/68 (70%)
Query: 192 GLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQ 251
G + A P ++ R YT+ Q+ ELE EFL N++I+R +R EL+ LNL+++ +KIWFQ
Sbjct: 136 GGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQ 195
Query: 252 NRRMKKKR 259
NRRMK K+
Sbjct: 196 NRRMKWKK 203
Score = 28.1 bits (61), Expect = 8.4
Identities = 16/37 (43%), Positives = 21/37 (56%)
Query: 32 NGGQLAALPPISYPRGALPWAATPASCAPAQPAGATA 68
+G +L ALPP P GA+P AA A+ P G +A
Sbjct: 231 SGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSA 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,248,120
Number of Sequences: 37866
Number of extensions: 684311
Number of successful extensions: 3973
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 303
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 3212
Number of HSP's gapped (non-prelim): 991
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.