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Search of human proteins with 194294551
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194294551 cysteine sulfinic acid decarboxylase [Homo
sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens] 1043 0.0
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens] 634 0.0
gi|197276620 glutamate decarboxylase 2 [Homo sapiens] 529 e-150
gi|4503875 glutamate decarboxylase 2 [Homo sapiens] 529 e-150
gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens] 528 e-150
gi|132814448 dopa decarboxylase (aromatic L-amino acid decarboxy... 118 1e-26
gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxyla... 118 1e-26
gi|92110055 histidine decarboxylase [Homo sapiens] 110 3e-24
gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens] 74 4e-13
gi|190341074 pyridoxal-dependent decarboxylase domain containing... 54 3e-07
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens] 34 0.28
gi|239755033 PREDICTED: hypothetical protein XP_002346199 [Homo ... 32 1.1
gi|239749533 PREDICTED: hypothetical protein XP_002347079 [Homo ... 32 1.1
gi|239743682 PREDICTED: hypothetical protein XP_002342945 [Homo ... 32 1.1
gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 31 2.4
gi|148539591 INO80 complex subunit D [Homo sapiens] 30 5.3
gi|126032348 hect domain and RLD 2 [Homo sapiens] 30 7.0
gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens] 30 7.0
gi|4757908 calcyphosine isoform a [Homo sapiens] 30 7.0
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 30 7.0
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 30 7.0
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 30 7.0
gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens] 29 9.1
>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
Length = 520
Score = 1043 bits (2696), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MSIPLKSSFLLSYLCTLPPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAI 60
MSIPLKSSFLLSYLCTLPPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAI
Sbjct: 1 MSIPLKSSFLLSYLCTLPPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAI 60
Query: 61 QKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQL 120
QKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQL
Sbjct: 61 QKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQL 120
Query: 121 FSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGS 180
FSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGS
Sbjct: 121 FSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGS 180
Query: 181 ISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKA 240
ISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKA
Sbjct: 181 ISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKA 240
Query: 241 DERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVD 300
DERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVD
Sbjct: 241 DERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVD 300
Query: 301 AAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQA 360
AAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQA
Sbjct: 301 AAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQA 360
Query: 361 SYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVE 420
SYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVE
Sbjct: 361 SYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVE 420
Query: 421 EMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMI 480
EMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMI
Sbjct: 421 EMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMI 480
Query: 481 GYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL 520
GYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL
Sbjct: 481 GYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL 520
>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
Length = 521
Score = 634 bits (1634), Expect = 0.0
Identities = 292/497 (58%), Positives = 386/497 (77%)
Query: 24 REILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLL 83
+ ++ D L D A E + ++++E + K T V++KVCEW+ PE+LKQLL
Sbjct: 25 KNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLL 84
Query: 84 DLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQY 143
DLE+R GE ++LE CR VI YSVKT HPRFFNQL++GLD ++L R +TE+LN S Y
Sbjct: 85 DLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVY 144
Query: 144 TYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGL 203
TYE++PVF+L+EE VL+K+ +GW GDGIF PGGS+SNMYA+NLARY+ PD K++GL
Sbjct: 145 TYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGL 204
Query: 204 RTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGA 263
P L LFTS ECHYS++K A+FLG+GT++V V+ D RGKM+PE+LE+Q+ A EGA
Sbjct: 205 SGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGA 264
Query: 264 VPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRA 323
PFLV ATSGTTVLGAFDPL+ IAD+C+RH LWLHVDA+WGGS L+S+ HR LL GI RA
Sbjct: 265 APFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRA 324
Query: 324 DSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQC 383
DSVAWNPHK+L AG+QC ALL++D S+LLK+C+ ++ASYLFQQDKFYDV+ DTGDK +QC
Sbjct: 325 DSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQC 384
Query: 384 GRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWF 443
RR D K W+ WKA G GLE R+++A L+RYLV+E+KKREGF+L+MEPE+ N+CFW+
Sbjct: 385 SRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWY 444
Query: 444 VPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTC 503
+PPSLR +E P++ +L+ VAP +KERM+K+GS+M+GYQPH + NFFR VV + ++
Sbjct: 445 IPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSR 504
Query: 504 ADMDFLLNELERLGQDL 520
DMDFLL+E++ LG+D+
Sbjct: 505 EDMDFLLDEIDLLGKDM 521
>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
Length = 585
Score = 529 bits (1363), Expect = e-150
Identities = 254/494 (51%), Positives = 361/494 (73%), Gaps = 7/494 (1%)
Query: 31 SEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQ 90
++ LP+ G+ + A L+ V +++ + K S KV ++ P EL Q + EL Q
Sbjct: 95 TDLLPACDGERPTL-AFLQDVMNILLQYVV-KSFDRSTKVIDFHYPNELLQEYNWELADQ 152
Query: 91 GESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPV 150
++ ++IL C+ ++Y++KTGHPR+FNQL +GLD LA +T + NT+ +TYEIAPV
Sbjct: 153 PQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPV 212
Query: 151 FVLMEEEVLRKLRALVGW--SSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPP 208
FVL+E L+K+R ++GW SGDGIF PGG+ISNMYA+ +AR++ +P+ K++G+ LP
Sbjct: 213 FVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALPR 272
Query: 209 LALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLV 268
L FTS+ H+S++KGAA LG+GTDSV ++K DERGKM+P DLER+I A+ +G VPFLV
Sbjct: 273 LIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLV 332
Query: 269 SATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAW 328
SAT+GTTV GAFDPL A+AD+C+++ +W+HVDAAWGG +L+S+ H+ L G++RA+SV W
Sbjct: 333 SATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTW 392
Query: 329 NPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVD 388
NPHK++ LQCSALL+++ L++ C+ ASYLFQQDK YD++ DTGDK +QCGR VD
Sbjct: 393 NPHKMMGVPLQCSALLVRE-EGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVD 451
Query: 389 CLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVME--PEFVNVCFWFVPP 446
KLWLMW+A+G G E +D+ LA YL +K REG+E+V + P+ NVCFW++PP
Sbjct: 452 VFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYIPP 511
Query: 447 SLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADM 506
SLR +++ + RLSKVAPV+K RM++ G+ M+ YQP G + NFFR+V++N A T D+
Sbjct: 512 SLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDI 571
Query: 507 DFLLNELERLGQDL 520
DFL+ E+ERLGQDL
Sbjct: 572 DFLIEEIERLGQDL 585
>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
Length = 585
Score = 529 bits (1363), Expect = e-150
Identities = 254/494 (51%), Positives = 361/494 (73%), Gaps = 7/494 (1%)
Query: 31 SEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQ 90
++ LP+ G+ + A L+ V +++ + K S KV ++ P EL Q + EL Q
Sbjct: 95 TDLLPACDGERPTL-AFLQDVMNILLQYVV-KSFDRSTKVIDFHYPNELLQEYNWELADQ 152
Query: 91 GESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPV 150
++ ++IL C+ ++Y++KTGHPR+FNQL +GLD LA +T + NT+ +TYEIAPV
Sbjct: 153 PQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPV 212
Query: 151 FVLMEEEVLRKLRALVGW--SSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPP 208
FVL+E L+K+R ++GW SGDGIF PGG+ISNMYA+ +AR++ +P+ K++G+ LP
Sbjct: 213 FVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALPR 272
Query: 209 LALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLV 268
L FTS+ H+S++KGAA LG+GTDSV ++K DERGKM+P DLER+I A+ +G VPFLV
Sbjct: 273 LIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLV 332
Query: 269 SATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAW 328
SAT+GTTV GAFDPL A+AD+C+++ +W+HVDAAWGG +L+S+ H+ L G++RA+SV W
Sbjct: 333 SATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTW 392
Query: 329 NPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVD 388
NPHK++ LQCSALL+++ L++ C+ ASYLFQQDK YD++ DTGDK +QCGR VD
Sbjct: 393 NPHKMMGVPLQCSALLVRE-EGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVD 451
Query: 389 CLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVME--PEFVNVCFWFVPP 446
KLWLMW+A+G G E +D+ LA YL +K REG+E+V + P+ NVCFW++PP
Sbjct: 452 VFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYIPP 511
Query: 447 SLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADM 506
SLR +++ + RLSKVAPV+K RM++ G+ M+ YQP G + NFFR+V++N A T D+
Sbjct: 512 SLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDI 571
Query: 507 DFLLNELERLGQDL 520
DFL+ E+ERLGQDL
Sbjct: 572 DFLIEEIERLGQDL 585
>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
Length = 594
Score = 528 bits (1359), Expect = e-150
Identities = 259/496 (52%), Positives = 356/496 (71%), Gaps = 10/496 (2%)
Query: 32 EALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLD---LELR 88
+ LP+ G+ V+ LL V ++ ++K S KV ++ P +L + ++ LEL
Sbjct: 102 DLLPAKNGEEQTVQFLLEVVD--ILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELS 159
Query: 89 SQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIA 148
ES +QIL CR ++Y V+TGHPRFFNQL +GLD LAG +T + NT+ +TYEIA
Sbjct: 160 DHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIA 219
Query: 149 PVFVLMEEEVLRKLRALVGWSS--GDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTL 206
PVFVLME+ L+K+R +VGWSS GDGIF PGG+ISNMY++ ARY+ +P+ K +G+ +
Sbjct: 220 PVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAV 279
Query: 207 PPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPF 266
P L LFTS++ HYSI+K A LG GTD+V ++K +ERGK++P D E +I A+ +G VPF
Sbjct: 280 PKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPF 339
Query: 267 LVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSV 326
V+AT+GTTV GAFDP++ IAD+C+++ LWLHVDAAWGG +L+S+ HRH L+GI+RA+SV
Sbjct: 340 YVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSV 399
Query: 327 AWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRR 386
WNPHK++ LQCSA+L+++ +L+ C+ A YLFQ DK YDV+ DTGDK +QCGR
Sbjct: 400 TWNPHKMMGVLLQCSAILVKE-KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRH 458
Query: 387 VDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVM--EPEFVNVCFWFV 444
VD K WLMWKA+G G E +I++ LA YL ++K RE FE+V EPE NVCFW++
Sbjct: 459 VDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYI 518
Query: 445 PPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCA 504
P SLRG +SP E+L KVAP +K M++ G+ M+GYQP G + NFFR+V++N A T +
Sbjct: 519 PQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQS 578
Query: 505 DMDFLLNELERLGQDL 520
D+DFL+ E+ERLGQDL
Sbjct: 579 DIDFLIEEIERLGQDL 594
>gi|132814448 dopa decarboxylase (aromatic L-amino acid
decarboxylase) [Homo sapiens]
Length = 480
Score = 118 bits (296), Expect = 1e-26
Identities = 91/384 (23%), Positives = 170/384 (44%), Gaps = 23/384 (5%)
Query: 75 EPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPH-ALAGRI 133
EP L+ L+ + ++ + I+ +I V H +F F + A+ +
Sbjct: 34 EPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADM 93
Query: 134 ITESLNTSQYTYEIAPVFVLMEE-------EVLRKLRALVGWSSGDGIFCPGGSISNMYA 186
+ ++ +++ +P +E ++L +A + +G+G GS S
Sbjct: 94 LCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATL 153
Query: 187 VNLARYQRY---------PDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRV 237
V L + P+ Q + + L ++S + H S+++ G+ ++
Sbjct: 154 VALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGLIGGV---KLKA 208
Query: 238 VKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 297
+ +D M L+ + +A G +PF + AT GTT +FD L + +C + +WL
Sbjct: 209 IPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWL 268
Query: 298 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHG 357
HVDAA+ GS + RHLL+G++ ADS +NPHK L CSA+ ++ ++ L
Sbjct: 269 HVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD-LTGAFR 327
Query: 358 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARY 417
+YL + + D + GRR LK+W +++ G +GL+ I + L+
Sbjct: 328 LDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHE 387
Query: 418 LVEEMKKREGFELVMEPEFVNVCF 441
+++ FE+ +E VCF
Sbjct: 388 FESLVRQDPRFEICVEVILGLVCF 411
>gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxylase)
[Homo sapiens]
Length = 480
Score = 118 bits (296), Expect = 1e-26
Identities = 91/384 (23%), Positives = 170/384 (44%), Gaps = 23/384 (5%)
Query: 75 EPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPH-ALAGRI 133
EP L+ L+ + ++ + I+ +I V H +F F + A+ +
Sbjct: 34 EPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADM 93
Query: 134 ITESLNTSQYTYEIAPVFVLMEE-------EVLRKLRALVGWSSGDGIFCPGGSISNMYA 186
+ ++ +++ +P +E ++L +A + +G+G GS S
Sbjct: 94 LCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATL 153
Query: 187 VNLARYQRY---------PDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRV 237
V L + P+ Q + + L ++S + H S+++ G+ ++
Sbjct: 154 VALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGLIGGV---KLKA 208
Query: 238 VKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 297
+ +D M L+ + +A G +PF + AT GTT +FD L + +C + +WL
Sbjct: 209 IPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWL 268
Query: 298 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHG 357
HVDAA+ GS + RHLL+G++ ADS +NPHK L CSA+ ++ ++ L
Sbjct: 269 HVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD-LTGAFR 327
Query: 358 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARY 417
+YL + + D + GRR LK+W +++ G +GL+ I + L+
Sbjct: 328 LDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHE 387
Query: 418 LVEEMKKREGFELVMEPEFVNVCF 441
+++ FE+ +E VCF
Sbjct: 388 FESLVRQDPRFEICVEVILGLVCF 411
>gi|92110055 histidine decarboxylase [Homo sapiens]
Length = 662
Score = 110 bits (275), Expect = 3e-24
Identities = 83/320 (25%), Positives = 142/320 (44%), Gaps = 25/320 (7%)
Query: 128 ALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGW----------SSGDGIFCP 177
+L G ++ +++N +T+ +P +E V+ L ++G S G G+
Sbjct: 89 SLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQS 148
Query: 178 GGSISNMYAVNLARYQRY-------PDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGL 230
S S + A+ AR + PD + L L + S + H S++K +
Sbjct: 149 TVSESTLIALLAARKNKILEMKTSEPDADESCLNAR--LVAYASDQAHSSVEKAGL---I 203
Query: 231 GTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVC 290
++ + D+ + E L++ I + G VP V AT GTT + AFD L + +C
Sbjct: 204 SLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPIC 263
Query: 291 QRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSN 350
R GLWLH+DAA+ G+ L R L GI+ ADS +NP K + C+ ++D
Sbjct: 264 AREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYK 323
Query: 351 LLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQ 410
L++ YL + VA D + RR +KLW + ++ G + L+ +
Sbjct: 324 -LQQTFSVNPIYLRHANS--GVATDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRH 380
Query: 411 AFVLARYLVEEMKKREGFEL 430
+A+Y ++ FE+
Sbjct: 381 GTEMAKYFESLVRNDPSFEI 400
>gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]
Length = 224
Score = 73.6 bits (179), Expect = 4e-13
Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 5/113 (4%)
Query: 32 EALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLD---LELR 88
+ LP+ G+ V+ LL V ++ ++K S KV ++ P +L + ++ LEL
Sbjct: 102 DLLPAKNGEEQTVQFLLEVVD--ILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELS 159
Query: 89 SQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTS 141
ES +QIL CR ++Y V+TGHPRFFNQL +GLD LAG +T + NT+
Sbjct: 160 DHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTN 212
>gi|190341074 pyridoxal-dependent decarboxylase domain containing 1
[Homo sapiens]
Length = 788
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 29/191 (15%)
Query: 245 KMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWG 304
K++ +D+ER G +P L+ A +GT +G D + + ++C+++G+WLHV+
Sbjct: 223 KLIKDDIER--------GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNL 274
Query: 305 GSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLF 364
++ L +L + DS+ P L + L + H A L
Sbjct: 275 ATLALGYVSSSVL-AAAKCDSMTMTPGPWLGLPAVPAVTLYK---------HDDPALTL- 323
Query: 365 QQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKK 424
VA T +K ++ L LWL + G G RI A L++ L E +KK
Sbjct: 324 -------VAGLTSNKPTD---KLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKK 373
Query: 425 REGFELVMEPE 435
++++E E
Sbjct: 374 VNYIKILVEDE 384
>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
Length = 568
Score = 34.3 bits (77), Expect = 0.28
Identities = 70/357 (19%), Positives = 131/357 (36%), Gaps = 33/357 (9%)
Query: 87 LRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHA-LAGRIITESLNTSQYTY 145
L SQG S +LE+ + R ++SG + L + + ++
Sbjct: 116 LPSQGLSSSAVLEKLKEYSSMDAFWQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHP 175
Query: 146 EIAPVFVLMEEEVLRKLRALV-GWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLR 204
+I P +E E++R +L G G GG+ S + A R + ++G++
Sbjct: 176 DIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAF----EKGIK 231
Query: 205 TLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAV 264
T +A + H + K A++ G+ V + K M+ D+ M A
Sbjct: 232 TPEIVA---PQSAHAAFNKAASYFGMKIVRVPLTK------MMEVDVR---AMRRAISRN 279
Query: 265 PFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTH-----RHLLD- 318
++ ++ G DP+ +A + ++ + LHVDA GG +++ H D
Sbjct: 280 TAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDF 339
Query: 319 GIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGD 378
++ S++ + HK A S +L D +Y F D + +
Sbjct: 340 RVKGVTSISADTHKYGYAPKGSSLVLYSDK---------KYRNYQFFVDTDWQGGIYASP 390
Query: 379 KVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPE 435
+ W G+ G Q AR+L E++ +G + P+
Sbjct: 391 TIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQ 447
>gi|239755033 PREDICTED: hypothetical protein XP_002346199 [Homo
sapiens]
Length = 537
Score = 32.3 bits (72), Expect = 1.1
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 25/120 (20%)
Query: 305 GSVLLSQTHRHLLDGIQRADSVAWNPHKLL-----------AAGLQCSALLLQDTSNLLK 353
G ++L HLL+G QR A NPH++L AG Q LLL N
Sbjct: 6 GLIILLLADPHLLEGGQRGQDGAANPHRVLELRRSNDLDLHRAGRQGGDLLLHPVGN--A 63
Query: 354 RCHGSQASYLFQQDK-FYDVALDTGDKV-----------VQCGRRVDCLKLWLMWKAQGD 401
R HG A K F DV + + V Q G+ +CL+ + A GD
Sbjct: 64 RVHGGAARQQCVGVKVFVDVHITLHNGVQGSFMDATGFHAQEGKLEECLRAAELLVADGD 123
>gi|239749533 PREDICTED: hypothetical protein XP_002347079 [Homo
sapiens]
Length = 537
Score = 32.3 bits (72), Expect = 1.1
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 25/120 (20%)
Query: 305 GSVLLSQTHRHLLDGIQRADSVAWNPHKLL-----------AAGLQCSALLLQDTSNLLK 353
G ++L HLL+G QR A NPH++L AG Q LLL N
Sbjct: 6 GLIILLLADPHLLEGGQRGQDGAANPHRVLELRRSNDLDLHRAGRQGGDLLLHPVGN--A 63
Query: 354 RCHGSQASYLFQQDK-FYDVALDTGDKV-----------VQCGRRVDCLKLWLMWKAQGD 401
R HG A K F DV + + V Q G+ +CL+ + A GD
Sbjct: 64 RVHGGAARQQCVGVKVFVDVHITLHNGVQGSFMDATGFHAQEGKLEECLRAAELLVADGD 123
>gi|239743682 PREDICTED: hypothetical protein XP_002342945 [Homo
sapiens]
Length = 537
Score = 32.3 bits (72), Expect = 1.1
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 25/120 (20%)
Query: 305 GSVLLSQTHRHLLDGIQRADSVAWNPHKLL-----------AAGLQCSALLLQDTSNLLK 353
G ++L HLL+G QR A NPH++L AG Q LLL N
Sbjct: 6 GLIILLLADPHLLEGGQRGQDGAANPHRVLELRRSNDLDLHRAGRQGGDLLLHPVGN--A 63
Query: 354 RCHGSQASYLFQQDK-FYDVALDTGDKV-----------VQCGRRVDCLKLWLMWKAQGD 401
R HG A K F DV + + V Q G+ +CL+ + A GD
Sbjct: 64 RVHGGAARQQCVGVKVFVDVHITLHNGVQGSFMDATGFHAQEGKLEECLRAAELLVADGD 123
>gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 985
Score = 31.2 bits (69), Expect = 2.4
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 276 VLGAFDPLEAIADVCQRHG--LWLHVDAAWGGSVLLSQTHRHLLD 318
V G F EA+A C R G + LHVD AW + T HLL+
Sbjct: 595 VCGGFILHEAVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLN 639
>gi|148539591 INO80 complex subunit D [Homo sapiens]
Length = 1027
Score = 30.0 bits (66), Expect = 5.3
Identities = 15/45 (33%), Positives = 21/45 (46%)
Query: 443 FVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGT 487
F PP +Q+ P H LS ++ LK +GS+ QP T
Sbjct: 194 FSPPPAPSQQQPPQQHSHLSPLSTSLKPPAPPQGSVCKSPQPQNT 238
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 29.6 bits (65), Expect = 7.0
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 2/63 (3%)
Query: 341 SALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQG 400
SA+ + LKRCH SQ L +L+ V Q R +D + W++ G
Sbjct: 2756 SAVFCGRSGKQLKRCHSSQPGMLLDSWSRMVKSLNVSSSVNQASRLIDGSE--PCWQSSG 2813
Query: 401 DQG 403
QG
Sbjct: 2814 SQG 2816
>gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens]
Length = 392
Score = 29.6 bits (65), Expect = 7.0
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 235 VRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHG 294
V + D G +++E G+A+ + P L+ T G + G PL+ ++C R+
Sbjct: 123 VHPMTKDPGGHYTLQEVEE--GLAQHK---PVLLFLTHGESSTGVLQPLDGFGELCHRYK 177
Query: 295 LWLHVD--AAWGGSVL 308
L VD A+ GG+ L
Sbjct: 178 CLLLVDSVASLGGTPL 193
>gi|4757908 calcyphosine isoform a [Homo sapiens]
Length = 189
Score = 29.6 bits (65), Expect = 7.0
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 18 PPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPE 77
PP +RE ++A + A +GD V LR V+ ++ G EW E E
Sbjct: 88 PPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSG--------EWTEDE 139
Query: 78 ELKQLLDLELRSQGESQKQILE 99
L++ LD S+ + Q + E
Sbjct: 140 VLRRFLDNFDSSEKDGQVTLAE 161
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 392 LWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGK 451
+W + GD L+ + F+LA +L + K + L + PE VPPS RG
Sbjct: 285 IWTLADVDGDGQLKA---EEFILAMHLTDMAKAGQPLPLTLPPE-------LVPPSFRGG 334
Query: 452 QESPDYHERLSKVAPVLKERMVKE 475
++ + L + +E K+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKK 358
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 392 LWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGK 451
+W + GD L+ + F+LA +L + K + L + PE VPPS RG
Sbjct: 285 IWTLADVDGDGQLKA---EEFILAMHLTDMAKAGQPLPLTLPPE-------LVPPSFRGG 334
Query: 452 QESPDYHERLSKVAPVLKERMVKE 475
++ + L + +E K+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKK 358
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 392 LWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGK 451
+W + GD L+ + F+LA +L + K + L + PE VPPS RG
Sbjct: 285 IWTLADVDGDGQLKA---EEFILAMHLTDMAKAGQPLPLTLPPE-------LVPPSFRGG 334
Query: 452 QESPDYHERLSKVAPVLKERMVKE 475
++ + L + +E K+
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKK 358
>gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]
Length = 457
Score = 29.3 bits (64), Expect = 9.1
Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 26/152 (17%)
Query: 156 EEVLRKLRALVGWSSGDGIFCPGGSISNMYAVN-LARYQRYPDCKQRGLRTLPPLALFTS 214
E +++ +L+G + IF G + SN A+ +AR+ Y K+ L T+
Sbjct: 104 ERARQQVASLIGADPREIIFTSGATESNNIAIKGVARF--YRSRKKH---------LITT 152
Query: 215 KECHYSIQKGAAFLGLGTDSVRVVKADE-RGKMVPEDLERQIGMAEAEGAVP---FLVSA 270
+ H + DS R ++A+ + +P I + E E A+ LVS
Sbjct: 153 QTEHKCV----------LDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSV 202
Query: 271 TSGTTVLGAFDPLEAIADVCQRHGLWLHVDAA 302
+ +G P+ I +C ++ H DAA
Sbjct: 203 MTVNNEIGVKQPIAEIGRICSSRKVYFHTDAA 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,382,459
Number of Sequences: 37866
Number of extensions: 826312
Number of successful extensions: 1800
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1776
Number of HSP's gapped (non-prelim): 24
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.