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Search of human proteins with 193788624
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
(472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 934 0.0
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 541 e-154
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 424 e-118
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 424 e-118
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 422 e-118
gi|117168277 amino acid transporter system A1 [Homo sapiens] 394 e-110
gi|117168275 amino acid transporter system A1 [Homo sapiens] 394 e-110
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 365 e-101
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 106 4e-23
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 103 3e-22
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 102 6e-22
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 102 8e-22
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 102 8e-22
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 69 7e-12
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 60 3e-09
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 53 5e-07
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 52 9e-07
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 44 2e-04
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 42 0.001
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 36 0.066
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 32 0.96
gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b prec... 31 2.1
gi|87567783 nicotinic cholinergic receptor alpha 1 isoform a pre... 31 2.1
gi|29789451 cation channel, sperm associated 3 [Homo sapiens] 30 4.7
gi|89044650 PREDICTED: acyl-malonyl condensing enzyme 1-like 1 [... 30 6.2
gi|22748975 acyl-malonyl condensing enzyme 1 [Homo sapiens] 29 8.1
gi|4504859 intermediate conductance calcium-activated potassium ... 29 8.1
gi|169212904 PREDICTED: acyl-malonyl condensing enzyme 1-like 1 ... 29 8.1
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 934 bits (2413), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNA 60
MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNA
Sbjct: 1 MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNA 60
Query: 61 IMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFG 120
IMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFG
Sbjct: 61 IMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFG 120
Query: 121 PAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVL 180
PAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVL
Sbjct: 121 PAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVL 180
Query: 181 IILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPS 240
IILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPS
Sbjct: 181 IILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPS 240
Query: 241 QGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGA 300
QGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGA
Sbjct: 241 QGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGA 300
Query: 301 MFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRA 360
MFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRA
Sbjct: 301 MFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRA 360
Query: 361 LQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIF 420
LQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIF
Sbjct: 361 LQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIF 420
Query: 421 YLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH 472
YLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH
Sbjct: 421 YLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH 472
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 541 bits (1394), Expect = e-154
Identities = 282/452 (62%), Positives = 341/452 (75%), Gaps = 17/452 (3%)
Query: 36 SKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYS 95
SK F DFEGKTSFGMSVFNLSNAIMGSGILGLAYAMA+TG+I FL LL +ALLSSYS
Sbjct: 54 SKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYS 113
Query: 96 IHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIG 155
IHLLL +G+ GIRAYEQLG RAFG GK+ A I L N+GAMSSYL+IIKSELPLVI
Sbjct: 114 IHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQ 173
Query: 156 TFLYMDPE-GDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIY 214
TFL ++ + DW++ GN L+I+VSV IILPLALM+ LGYLGY+SG SL+CM+FFL++VIY
Sbjct: 174 TFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIY 233
Query: 215 KKFQLGCAI-----------GHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVP 263
KKF + C + H E E L P ++ C FT++SQ +YT+P
Sbjct: 234 KKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPE--ASAFCTPSYFTLNSQTAYTIP 291
Query: 264 IMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAE 323
IMAFAFVCHPEVLPIYTEL PSK++MQ ++N+SI M+ MY L A FGYLTFY+ V++E
Sbjct: 292 IMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESE 351
Query: 324 MLHMYSQKDP---LILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIA 380
+LH YS+ DP LILCVR+AVL AVTLTVP+VLFP+RRA+QQ+LFP + FSW RHV IA
Sbjct: 352 LLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIA 411
Query: 381 LILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQA 440
+ LL +N+LVI P I IFGVIG+TSAP LIFI P+IFY RI+P+E EP S PKI A
Sbjct: 412 VGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILA 471
Query: 441 LCFGVLGVLFMAVSLGFMFANWATGQSRMSGH 472
LCF +LG L M +SL F+ +WA+G SR G+
Sbjct: 472 LCFAMLGFLLMTMSLSFIIIDWASGTSRHGGN 503
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 424 bits (1089), Expect = e-118
Identities = 240/467 (51%), Positives = 306/467 (65%), Gaps = 52/467 (11%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105
G TSFGMS FNLSNAIMGSGILGL+YAMA+TG+I F+ +LL +A+LS YS+HLLL A
Sbjct: 73 GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132
Query: 106 AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE-G 164
G YE+LG++AFG GK+ I + N+GAMSSYLFIIK ELP VI F+ ++ G
Sbjct: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192
Query: 165 DWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIG 224
+W+L GN LII VSV IILPL+L+K+LGYLGYTSG SLTCM+FF+ VIYKKFQ+ C +
Sbjct: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
Query: 225 -----------HNETAM-----------------------------ESEALVGLPSQGL- 243
+N M E++A L G+
Sbjct: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312
Query: 244 -----NSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSI 298
+ CE + F +S+ +Y +PI+ FAFVCHPEVLPIY+EL S+R+MQ V+N+SI
Sbjct: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372
Query: 299 GAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPL---ILCVRLAVLLAVTLTVPVVLF 355
M MY L A FGYLTFY V+ E+LH YS+ L +L VRLAVL+AVTLTVP+VLF
Sbjct: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432
Query: 356 PIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFI 415
PIR ++ LLFP + FSW RH IA +L+ L NVLVI VPTI+ IFG IG++SA LIFI
Sbjct: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492
Query: 416 LPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
LP++FYL++V E F S K+ AL F V+G+ FM S+ + +W
Sbjct: 493 LPAVFYLKLVKKET--FRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 424 bits (1089), Expect = e-118
Identities = 240/467 (51%), Positives = 306/467 (65%), Gaps = 52/467 (11%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105
G TSFGMS FNLSNAIMGSGILGL+YAMA+TG+I F+ +LL +A+LS YS+HLLL A
Sbjct: 73 GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132
Query: 106 AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE-G 164
G YE+LG++AFG GK+ I + N+GAMSSYLFIIK ELP VI F+ ++ G
Sbjct: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192
Query: 165 DWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIG 224
+W+L GN LII VSV IILPL+L+K+LGYLGYTSG SLTCM+FF+ VIYKKFQ+ C +
Sbjct: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
Query: 225 -----------HNETAM-----------------------------ESEALVGLPSQGL- 243
+N M E++A L G+
Sbjct: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312
Query: 244 -----NSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSI 298
+ CE + F +S+ +Y +PI+ FAFVCHPEVLPIY+EL S+R+MQ V+N+SI
Sbjct: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372
Query: 299 GAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPL---ILCVRLAVLLAVTLTVPVVLF 355
M MY L A FGYLTFY V+ E+LH YS+ L +L VRLAVL+AVTLTVP+VLF
Sbjct: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432
Query: 356 PIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFI 415
PIR ++ LLFP + FSW RH IA +L+ L NVLVI VPTI+ IFG IG++SA LIFI
Sbjct: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492
Query: 416 LPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
LP++FYL++V E F S K+ AL F V+G+ FM S+ + +W
Sbjct: 493 LPAVFYLKLVKKET--FRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 422 bits (1086), Expect = e-118
Identities = 242/471 (51%), Positives = 304/471 (64%), Gaps = 18/471 (3%)
Query: 6 PKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSG 65
P AL S E + FL G K + G TSFGMSVFNLSNAI+GSG
Sbjct: 31 PTKQAALKSHYADVDPENQNFLLESNL--GKKKYETEFHPGTTSFGMSVFNLSNAIVGSG 88
Query: 66 ILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKV 125
ILGL+YAMA+TG+ F+ LL +++ S YS+HLLL A G YEQLG +AFG GK+
Sbjct: 89 ILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKL 148
Query: 126 VVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYM-DPEGDWFLKGNLLIIIVSVLIILP 184
+ I + N+GAMSSYLFI+K ELPLVI + D G W+L GN L+++VS+++ILP
Sbjct: 149 AASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILP 208
Query: 185 LALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGH--------NETAMESEALV 236
L+L ++LGYLGYTSGLSL CM+FFL+ VI KKFQ+ C + N T + ALV
Sbjct: 209 LSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALV 268
Query: 237 GLPSQGL--NSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVA 294
S + N SC F +SQ Y VPI+ F+FVCHP VLPIY EL S+RRM V+
Sbjct: 269 PALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVS 328
Query: 295 NVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQ---KDPLILCVRLAVLLAVTLTVP 351
+S AMF MY L A FGYLTFY V++E+LH YS D L+L VRLAVL+AVTLTVP
Sbjct: 329 KISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVP 388
Query: 352 VVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPS 411
VV+FPIR ++ LL K FSW RH I + +L N+LVI VPTIRDIFG IG+++A
Sbjct: 389 VVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASM 448
Query: 412 LIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
LIFILPS FY+++V + EP S KI AL F + GVL M S+ + +W
Sbjct: 449 LIFILPSAFYIKLV--KKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDW 497
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 394 bits (1013), Expect = e-110
Identities = 218/430 (50%), Positives = 289/430 (67%), Gaps = 14/430 (3%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105
G TS GMSVFNLSNAIMGSGILGLA+A+A+TG++ FL LL + LLS YSI+LLL C+
Sbjct: 69 GTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKE 128
Query: 106 AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE-- 163
G YE+LG++ FG GK V+ L N GAM SYLFI+K+ELP I FL E
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAI-KFLMGKEETF 187
Query: 164 GDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAI 223
W++ G +L++IV+ IILPL L+K+LGYLGYTSG SL+CM+FFL+ VIYKKFQ+ C +
Sbjct: 188 SAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIV 247
Query: 224 GHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELC 283
+ + + + +C + T +S+ Y +P +AFAFVCHP VLPIY+EL
Sbjct: 248 PELNSTISANSTNA-------DTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300
Query: 284 RPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDP-LILCVRLAV 342
S+++MQ V+N+S AMF MY LTA FGYLTFY +V++++LH Y KD LIL VRLAV
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360
Query: 343 LLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFG 402
++AV LTVPV+ F +R +L +L K F+ RH + ILLV++N+LVI +P+++DIFG
Sbjct: 361 IVAVILTVPVLFFTVRSSLFELAKKTK-FNLCRHTVVTCILLVVINLLVIFIPSMKDIFG 419
Query: 403 VIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
V+G TSA LIFILPS YL+I + + +I A F LGVLF VS+ + +W
Sbjct: 420 VVGVTSANMLIFILPSSLYLKITDQDGDK--GTQRIWAALFLGLGVLFSLVSIPLVIYDW 477
Query: 463 ATGQSRMSGH 472
A S GH
Sbjct: 478 ACSSSSDEGH 487
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 394 bits (1013), Expect = e-110
Identities = 218/430 (50%), Positives = 289/430 (67%), Gaps = 14/430 (3%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105
G TS GMSVFNLSNAIMGSGILGLA+A+A+TG++ FL LL + LLS YSI+LLL C+
Sbjct: 69 GTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKE 128
Query: 106 AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE-- 163
G YE+LG++ FG GK V+ L N GAM SYLFI+K+ELP I FL E
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAI-KFLMGKEETF 187
Query: 164 GDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAI 223
W++ G +L++IV+ IILPL L+K+LGYLGYTSG SL+CM+FFL+ VIYKKFQ+ C +
Sbjct: 188 SAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIV 247
Query: 224 GHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELC 283
+ + + + +C + T +S+ Y +P +AFAFVCHP VLPIY+EL
Sbjct: 248 PELNSTISANSTNA-------DTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300
Query: 284 RPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDP-LILCVRLAV 342
S+++MQ V+N+S AMF MY LTA FGYLTFY +V++++LH Y KD LIL VRLAV
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360
Query: 343 LLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFG 402
++AV LTVPV+ F +R +L +L K F+ RH + ILLV++N+LVI +P+++DIFG
Sbjct: 361 IVAVILTVPVLFFTVRSSLFELAKKTK-FNLCRHTVVTCILLVVINLLVIFIPSMKDIFG 419
Query: 403 VIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
V+G TSA LIFILPS YL+I + + +I A F LGVLF VS+ + +W
Sbjct: 420 VVGVTSANMLIFILPSSLYLKITDQDGDK--GTQRIWAALFLGLGVLFSLVSIPLVIYDW 477
Query: 463 ATGQSRMSGH 472
A S GH
Sbjct: 478 ACSSSSDEGH 487
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 365 bits (938), Expect = e-101
Identities = 194/417 (46%), Positives = 266/417 (63%), Gaps = 12/417 (2%)
Query: 49 SFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGI 108
SFG+SVFNL NAIMGSGILGLAY MA+TGV F LLL +ALL+SYS+HLLL+ +
Sbjct: 46 SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAV 105
Query: 109 RAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFL 168
+YE LG AFG GK+VVA I + N+GAMSSYL IIK+ELP I FL D W+L
Sbjct: 106 TSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYL 165
Query: 169 KGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNET 228
G L+II+ V I+ PLAL+ +G+LGYTS LS M+FF + VI KK+ + C + N
Sbjct: 166 DGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYV 225
Query: 229 AMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKR 288
G + C+ ++F + +Y +P MAF+F+CH +LPIY EL PSK+
Sbjct: 226 EK------GFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKK 279
Query: 289 RMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQ---KDPLILCVRLAVLLA 345
RMQ V N +I F +Y ++A FGYLTFY V++E+L YS+ D +++ V+L +L A
Sbjct: 280 RMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFA 339
Query: 346 VTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIG 405
V LTVP++ FP R+A+ + F FSW RH I L L +++ +L I VP IR++FGV+G
Sbjct: 340 VLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVG 399
Query: 406 STSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
++++ LIFI P +FYL++ E FLSW K+ A + G+L SL + +W
Sbjct: 400 ASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDW 453
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 106 bits (265), Expect = 4e-23
Identities = 106/444 (23%), Positives = 192/444 (43%), Gaps = 49/444 (11%)
Query: 31 GPAPGSKPVQFMDFEGKTSFGMS----VFNLSNAIMGSGILGLAYAMAHTGVIF--FLAL 84
G PGS+ + + +S VF L + +G+G+L +A + G + FL
Sbjct: 3 GQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVE 62
Query: 85 LLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLF 144
L+ + L S + +L A ++G Y+ + + GPA + L+ + ++L
Sbjct: 63 LVSLVFLIS-GLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLR 121
Query: 145 IIKSELPLVIGTFLYMDPEGD--WFLKGNLLIIIVSVLIILPLALMKHLGYLGYTS--GL 200
+I +L + + L P W+ + ++SVL+ILPL+ + + + YTS G
Sbjct: 122 VIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGT 181
Query: 201 SLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSY 260
C L +++V Y + G LV L+ + +F+V
Sbjct: 182 LAACYLALVITVQYYLWPQG--------------LVRESHPSLSPASWTSVFSV------ 221
Query: 261 TVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSV 320
P + F F CH + IY + + S V+ +S+ A +Y LT +G+LTF + V
Sbjct: 222 -FPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEV 280
Query: 321 KAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSW-PRHVA- 378
A++L Y D +I+ R+ +++ P+VLF R +Q W P +A
Sbjct: 281 SADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALAD 340
Query: 379 ---------IALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEV 429
+ ++ + + + + +P + +I +IG S+ IFI P + I V
Sbjct: 341 PSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIFIFPGL--CLICAMGV 397
Query: 430 EPFLSWPKIQALCFGVLGVLFMAV 453
EP P+++ C V GV+ + V
Sbjct: 398 EPI--GPRVKC-CLEVWGVVSVLV 418
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 103 bits (257), Expect = 3e-22
Identities = 96/428 (22%), Positives = 180/428 (42%), Gaps = 34/428 (7%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTG-VIFFLALLLCIALLSSYSIHLLLTCAG 104
G TS ++F + NA +G+G+L A + G V +AL + + + + +L C+
Sbjct: 49 GTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQ 108
Query: 105 IAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEG 164
+ R Y+++ G V+ I ++ G ++L II + +I + +PEG
Sbjct: 109 ASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAV-MAKEPEG 167
Query: 165 ---DWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGC 221
W+ I + + L ILPL++ + +G+ Y S LS+ + VI K
Sbjct: 168 ASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIW--- 224
Query: 222 AIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTE 281
+ M ++ P+ + + +P + F F CH +P++
Sbjct: 225 ----PDKEMTPGNILTRPASWM-------------AVFNAMPTICFGFQCHVSSVPVFNS 267
Query: 282 LCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLA 341
+ +P + V ++ +Y T G+LTF ++V ++L Y +D + R
Sbjct: 268 MQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAF 327
Query: 342 VLLAVTLTVPVVLFPIRRALQQLLFPGKAF--------SWPRHVAIALILLVLVNVLVIC 393
++L+V + P++ F R ++ L + R V L+ +L +L +
Sbjct: 328 IILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALF 387
Query: 394 VPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAV 453
+P I + VIG +A IF+ P + ++ SE+E + +GVL V A
Sbjct: 388 IPDIGKVISVIGGLAA-CFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAF 446
Query: 454 SLGFMFAN 461
G AN
Sbjct: 447 IFGQTTAN 454
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 102 bits (255), Expect = 6e-22
Identities = 97/390 (24%), Positives = 171/390 (43%), Gaps = 54/390 (13%)
Query: 73 MAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVIC 132
M G + LL ++ ++ +S+ LL+ ++G Y+ L + FG G ++++ +
Sbjct: 1 MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60
Query: 133 LHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLG 192
L Y FI+ DPE + F+ + +I + +V LPL+L +++
Sbjct: 61 L--------YPFIV--------------DPE-NVFIGRHFIIGLSTVTFTLPLSLYRNIA 97
Query: 193 YLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMF 252
LG S +S L V+ + LG I E +A +F
Sbjct: 98 KLGKVSLISTGLTTLILGIVMARAISLGPHIPKTE--------------------DAWVF 137
Query: 253 TVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFG 312
+ + V +M+FAF+CH +Y+ L P+ + + ++SI + AT G
Sbjct: 138 AKPNAIQ-AVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCG 196
Query: 313 YLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFS 372
YLTF + ++ Y + D L+ R + V LT P+ F R + + F G S
Sbjct: 197 YLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSS 256
Query: 373 WPRHVAIALILLV--LVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVE 430
V +++ V LV++L+ C+ + ++ GV+ +T LIFI+PS YL++ E
Sbjct: 257 VFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCAT---PLIFIIPSACYLKL---SEE 310
Query: 431 PFLSWPKIQALCFGVLGVLFMAVSLGFMFA 460
P KI + +G + M GF+ A
Sbjct: 311 PRTHSDKIMSCVMLPIGAVVMV--FGFVMA 338
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 102 bits (254), Expect = 8e-22
Identities = 86/382 (22%), Positives = 168/382 (43%), Gaps = 35/382 (9%)
Query: 54 VFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQ 113
+ N+ N+I+G +L + + G++ LL+ + ++ S L+ A ++ R Y
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 114 LGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLL 173
L A+G AGK++V T + +G ++ +++ +L L+ G F L
Sbjct: 72 LAFHAYGKAGKMLVETSMIGLMLGTCIAF-YVVIGDLGSNFFARLFGFQVGGTFRM--FL 128
Query: 174 IIIVSVLIILPLALMKH-LGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMES 232
+ VS+ I+LPL+L ++ + + S ++L F+ ++ + G G +
Sbjct: 129 LFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSY 188
Query: 233 EALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQA 292
G + +PI +F C +VLP Y L PS + M +
Sbjct: 189 VRWEG--------------------VFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSS 228
Query: 293 VANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPV 352
+ S+ + Y + FGY++F + +L M+ + + +R+ +++V + P+
Sbjct: 229 IFASSLNVVTTFYVMVGFFGYVSFTEATAGNVL-MHFPSNLVTEMLRVGFMMSVAVGFPM 287
Query: 353 VLFPIRRALQQLL---------FPGKAFSWP-RHVAIALILLVLVNVLVICVPTIRDIFG 402
++ P R+AL LL F + P R A+ L ++ V I +P + I G
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILG 347
Query: 403 VIGSTSAPSLIFILPSIFYLRI 424
+ G+T + FI P++ Y +I
Sbjct: 348 LTGATMGSLICFICPALIYKKI 369
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 102 bits (254), Expect = 8e-22
Identities = 86/382 (22%), Positives = 168/382 (43%), Gaps = 35/382 (9%)
Query: 54 VFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQ 113
+ N+ N+I+G +L + + G++ LL+ + ++ S L+ A ++ R Y
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 114 LGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLL 173
L A+G AGK++V T + +G ++ +++ +L L+ G F L
Sbjct: 72 LAFHAYGKAGKMLVETSMIGLMLGTCIAF-YVVIGDLGSNFFARLFGFQVGGTFRM--FL 128
Query: 174 IIIVSVLIILPLALMKH-LGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMES 232
+ VS+ I+LPL+L ++ + + S ++L F+ ++ + G G +
Sbjct: 129 LFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSY 188
Query: 233 EALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQA 292
G + +PI +F C +VLP Y L PS + M +
Sbjct: 189 VRWEG--------------------VFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSS 228
Query: 293 VANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPV 352
+ S+ + Y + FGY++F + +L M+ + + +R+ +++V + P+
Sbjct: 229 IFASSLNVVTTFYVMVGFFGYVSFTEATAGNVL-MHFPSNLVTEMLRVGFMMSVAVGFPM 287
Query: 353 VLFPIRRALQQLL---------FPGKAFSWP-RHVAIALILLVLVNVLVICVPTIRDIFG 402
++ P R+AL LL F + P R A+ L ++ V I +P + I G
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILG 347
Query: 403 VIGSTSAPSLIFILPSIFYLRI 424
+ G+T + FI P++ Y +I
Sbjct: 348 LTGATMGSLICFICPALIYKKI 369
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 69.3 bits (168), Expect = 7e-12
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 74/402 (18%)
Query: 55 FNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQL 114
+N++NAI G +LGL YA+ H G + L L++ A++ Y+ +L+ C YE+
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACL-------YEEN 174
Query: 115 --GQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNL 172
G+ V +A C + + + + LV+ LY+ + GNL
Sbjct: 175 EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYV------VVSGNL 228
Query: 173 LI-------------IIVSVLIILPLALMKHLGYLGYTSGLSLTCML-FFLVSVIYKKFQ 218
+ I++ ++LP A +K+L + S SL C L F+++++ +
Sbjct: 229 MYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYC 285
Query: 219 LGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVD-SQMSYTVPIMAFAFVCHPEVLP 277
L S+ + + E F +D + ++ I+ F++ +
Sbjct: 286 L--------------------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPS 325
Query: 278 IYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILC 337
+ + +PS+ + N + A + GL A YLT+ K + + +
Sbjct: 326 LEGNMQQPSE--FHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITD--NLPGSIRAV 381
Query: 338 VRLAVLLAVTLTVPVVLFPIRRALQQLLFP--------------GKAFSWPRHVAIALIL 383
V + ++ L+ P+ F L++ LF G+ SW + AL++
Sbjct: 382 VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVV 441
Query: 384 LVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIV 425
L+ + I VP + G+ GS + L F+LPS+F+LR++
Sbjct: 442 FTLL--MAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 60.5 bits (145), Expect = 3e-09
Identities = 95/473 (20%), Positives = 183/473 (38%), Gaps = 89/473 (18%)
Query: 34 PGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSS 93
P K Q D EG SF ++ +L +G+G+LGL A+ + G++ L+ I ++S
Sbjct: 46 PVQKHYQLDDQEG-ISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISV 104
Query: 94 YSIHLLLTCAGIAGIR------AYEQLGQRAFGPA-----------GKVVVATVICLHNV 136
+ +H+L+ C+ +R Y A + G+ VV + + +
Sbjct: 105 HCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQL 164
Query: 137 GAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGN-----------------LLIIIVSV 179
G S Y+ + + V FL E F+ + +L + +
Sbjct: 165 GFCSVYIVFLAENVKQVHEGFL----ESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFI 220
Query: 180 LIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLP 239
++++ + +K+L L + + +S+ L +IY+ HN LP
Sbjct: 221 ILLVFIRELKNLFVLSFLANVSMAVSLV----IIYQYVVRNMPDPHN-----------LP 265
Query: 240 SQGLNSSCEAQMFTVDSQMSYTV--PIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVS 297
V Y + FAF VLP+ ++ + SKR QA+ N+
Sbjct: 266 -------------IVAGWKKYPLFFGTAVFAFEGIGVVLPLENQM-KESKRFPQAL-NIG 310
Query: 298 IGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPI 357
+G + +Y AT GY+ F+ +K + Q L V++ + +T + +
Sbjct: 311 MGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFY-- 368
Query: 358 RRALQQLLFPGKA----FSWPR--HVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPS 411
+++ PG W + I L+ + I +P + + +G+ S+ +
Sbjct: 369 --VPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSST 426
Query: 412 LIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWAT 464
L ILP + + I+ E + W ++ + GV +GF+ + T
Sbjct: 427 LALILPPL--VEILTFSKEHYNIWMVLKNISIAFTGV------VGFLLGTYIT 471
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 53.1 bits (126), Expect = 5e-07
Identities = 86/425 (20%), Positives = 172/425 (40%), Gaps = 82/425 (19%)
Query: 47 KTSFGMSVF----NLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTC 102
K + G++VF +L MG+GILGL A+ + G++ LL + ++ + +H+L+ C
Sbjct: 49 KKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKC 108
Query: 103 AG-----------------IAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFI 145
A + G+ A + G+ +V+ + + +G Y+
Sbjct: 109 AQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVF 168
Query: 146 IKSELPLVIGTF------------LYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGY 193
+ L V+ + + P D + L ++ + ++ L L+++L
Sbjct: 169 LADNLKQVVEAVNSTTNNCYSNETVILTPTMD-----SRLYMLSFLPFLVLLVLIRNLRI 223
Query: 194 LGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFT 253
L S L+ ML LV +I Q +P +++
Sbjct: 224 LTIFSMLANISMLVSLVIIIQYITQ------------------EIPDP-------SRLPL 258
Query: 254 VDSQMSYTV--PIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATF 311
V S +Y + F+F VLP+ ++ + R A+ ++ + + +Y A
Sbjct: 259 VASWKTYPLFFGTAIFSFESIGVVLPLENKM--KNARHFPAILSLGMSIVTSLYIGMAAL 316
Query: 312 GYLTFYSSVKAEM-LHMYS----QKDPLILCVRLAVLLAVTLTVP---VVLFPIRRALQQ 363
GYL F +KA + L++ + Q L+ + A+ VP ++ F I R +
Sbjct: 317 GYLRFGDDIKASISLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTR 376
Query: 364 LLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLR 423
++ P ++I L+++ L +L I +P + + ++GS S +L I+P + +
Sbjct: 377 -------WALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVT 429
Query: 424 IVPSE 428
SE
Sbjct: 430 TFYSE 434
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 52.4 bits (124), Expect = 9e-07
Identities = 98/435 (22%), Positives = 178/435 (40%), Gaps = 57/435 (13%)
Query: 45 EGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAG 104
E S ++ +L +G+G+LGL A+ + G++ LL I +L+ + + +LL CA
Sbjct: 39 EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
Query: 105 -----------------IAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIK 147
+ G+ RA G+ V+ ++ + +G S Y +
Sbjct: 99 HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158
Query: 148 SELPLVIG----TFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLT 203
L ++ T P L +L I +LIILP ++ L + L +
Sbjct: 159 DNLQQMVEKAHVTSNICQPREILTLTP-ILDIRFYMLIILPFLIL-----LVFIQNLKVL 212
Query: 204 CMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVP 263
+ L ++ LG E ME G+P N A T + +
Sbjct: 213 SVFSTLANIT----TLGSMALIFEYIME-----GIPYPS-NLPLMANWKTF--LLFFGTA 260
Query: 264 IMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAE 323
I F V VLP+ ++ P ++ V + + + +Y L T GY+ F S +A
Sbjct: 261 IFTFEGV--GMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQAS 316
Query: 324 M-LHMYS----QKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVA 378
+ L++ + Q L+ + + A+ VP + I A+ Q+ + SW V
Sbjct: 317 ITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEII-IPFAISQV-----SESWALFVD 370
Query: 379 IAL--ILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWP 436
+++ L+ L V I +P + + ++GS S+ +L I+P++ + I SE ++
Sbjct: 371 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 430
Query: 437 K-IQALCFGVLGVLF 450
K I G+LG +F
Sbjct: 431 KDIMISIVGLLGCIF 445
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 44.3 bits (103), Expect = 2e-04
Identities = 87/456 (19%), Positives = 169/456 (37%), Gaps = 92/456 (20%)
Query: 46 GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105
GK + +++F + N +MG+ IL + + + G + +++ + LL+ Y + ++ +
Sbjct: 115 GKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYCCYRVVKSRTM 174
Query: 106 -----AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFL-- 158
Y + + FG G+ + +GAM Y +++ S G F+
Sbjct: 175 MFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVY-WVLMSNFLFNTGKFIFN 233
Query: 159 --------------------------------------YMDPEG-----DWFLKGNLLII 175
Y + G W+ K +
Sbjct: 234 FIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWWDKSRTVPF 293
Query: 176 IVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEAL 235
+ V ++LPL K + + L +L+ + V +K +LG + E
Sbjct: 294 YL-VGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHL---------EFH 343
Query: 236 VGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVAN 295
+P+ E + + Q ++ AF H ++ L + +K++ V +
Sbjct: 344 WFIPT-------EFFVPEIRFQFPQLTGVLTLAFFIHNCIIT----LLKNNKKQENNVRD 392
Query: 296 VSIGAMFCMYGLTATF---GYLTFYS---------SVKAEMLHMYSQKDPLILCVRLAVL 343
+ I M +T T+ G L F S ++ L + D L R+ +L
Sbjct: 393 LCIAYML----VTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLL 448
Query: 344 LAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICV-PTIRDIFG 402
+ P++ + R L +F G + HV I +++V V++ C P I I
Sbjct: 449 FQMMTVYPLLGYLARVQLLGHIF-GDIYPSIFHVLILNLIIVGAGVIMACFYPNIGGIIR 507
Query: 403 VIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKI 438
G+ + +FI PS+ Y I+ E L+WPK+
Sbjct: 508 YSGAACGLAFVFIYPSLIY--IISLHQEERLTWPKL 541
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 16/184 (8%)
Query: 275 VLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEM-LHMYS---- 329
VLP+ ++ P ++ V + + + +Y L T GY+ F S +A + L++ +
Sbjct: 311 VLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLY 368
Query: 330 QKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIAL--ILLVLV 387
Q L+ + + A+ VP + I A+ Q+ + SW V +++ L+ L
Sbjct: 369 QSVKLMYSIGIFFTYALQFHVPAEII-IPFAISQV-----SESWALFVDLSVRSALVCLT 422
Query: 388 NVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPK-IQALCFGVL 446
V I +P + + ++GS S+ +L I+P++ + I SE ++ K I G+L
Sbjct: 423 CVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLL 482
Query: 447 GVLF 450
G +F
Sbjct: 483 GCIF 486
Score = 33.9 bits (76), Expect = 0.33
Identities = 18/59 (30%), Positives = 33/59 (55%)
Query: 45 EGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCA 103
E S ++ +L +G+G+LGL A+ + G++ LL I +L+ + + +LL CA
Sbjct: 39 EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCA 97
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 36.2 bits (82), Expect = 0.066
Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 28 PSRGPAPGSKPVQFMDF--EGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALL 85
PS G S P + F T++ ++ +L +G+G+LGL A+ + G++ L
Sbjct: 25 PSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISL 84
Query: 86 LCIALLSSYSIHLLLTCA 103
L I +++ + + +L+ CA
Sbjct: 85 LIIGIVAVHCMGILVKCA 102
Score = 32.7 bits (73), Expect = 0.73
Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 23/173 (13%)
Query: 267 FAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEM-L 325
F+F VLP+ ++ P R+ + + + + +Y GYL F ++++ + L
Sbjct: 267 FSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITL 324
Query: 326 HMYS----QKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIAL 381
++ + Q L+ + + A+ VP +++ P P H + +
Sbjct: 325 NLPNCWLYQSVKLLYSIGIFFTYALQFYVPA----------EIIIPFFVSRAPEHCELVV 374
Query: 382 ------ILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSE 428
+L+ L +L I +P + + ++GS S+ +L I+P + + SE
Sbjct: 375 DLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSE 427
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 32.3 bits (72), Expect = 0.96
Identities = 16/40 (40%), Positives = 25/40 (62%)
Query: 329 SQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPG 368
S DPLIL + L +++ + L + L RRAL+Q ++PG
Sbjct: 246 SDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPG 285
>gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b
precursor [Homo sapiens]
Length = 457
Score = 31.2 bits (69), Expect = 2.1
Identities = 21/87 (24%), Positives = 38/87 (43%)
Query: 339 RLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIR 398
RL + V + +P +LF L L +++ L L V + V+V +P+
Sbjct: 229 RLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTS 288
Query: 399 DIFGVIGSTSAPSLIFILPSIFYLRIV 425
+IG +++F++ SI IV
Sbjct: 289 SAVPLIGKYMLFTMVFVIASIIITVIV 315
>gi|87567783 nicotinic cholinergic receptor alpha 1 isoform a
precursor [Homo sapiens]
Length = 482
Score = 31.2 bits (69), Expect = 2.1
Identities = 21/87 (24%), Positives = 38/87 (43%)
Query: 339 RLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIR 398
RL + V + +P +LF L L +++ L L V + V+V +P+
Sbjct: 254 RLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTS 313
Query: 399 DIFGVIGSTSAPSLIFILPSIFYLRIV 425
+IG +++F++ SI IV
Sbjct: 314 SAVPLIGKYMLFTMVFVIASIIITVIV 340
>gi|29789451 cation channel, sperm associated 3 [Homo sapiens]
Length = 398
Score = 30.0 bits (66), Expect = 4.7
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Query: 142 YLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLG 192
++ I SEL + + Y+DP W NLL +I+ +++ LP AL + +G
Sbjct: 90 FVSICTSELSMKV----YVDPINYWKNGYNLLDVIIIIVMFLPYALRQLMG 136
>gi|89044650 PREDICTED: acyl-malonyl condensing enzyme 1-like 1
[Homo sapiens]
Length = 338
Score = 29.6 bits (65), Expect = 6.2
Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 13/74 (17%)
Query: 377 VAIALILLVLVNV-LVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSW 435
+A++L LLV ++ C+PT+ + G++G + +F+L S ++PS++ LSW
Sbjct: 201 LALSLGLLVYRSLHFPSCLPTVAFLSGLVGLLGSVPGLFVLQS----PVLPSDL---LSW 253
Query: 436 PKIQALCFGVLGVL 449
C G +G+L
Sbjct: 254 S-----CVGAVGIL 262
>gi|22748975 acyl-malonyl condensing enzyme 1 [Homo sapiens]
Length = 338
Score = 29.3 bits (64), Expect = 8.1
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 17/76 (22%)
Query: 377 VAIALILLVLVNV-LVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLR--IVPSEVEPFL 433
+A++L LLV ++ C+PT+ + G++G L+ +P +F L+ ++PS++ L
Sbjct: 201 LALSLRLLVYRSLHFPPCLPTVAFLSGLVG------LLGSVPGLFVLQAPVLPSDL---L 251
Query: 434 SWPKIQALCFGVLGVL 449
SW C G +G+L
Sbjct: 252 SWS-----CVGAVGIL 262
>gi|4504859 intermediate conductance calcium-activated potassium
channel protein 1 [Homo sapiens]
Length = 427
Score = 29.3 bits (64), Expect = 8.1
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 413 IFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAV 453
++++P I +L I +V P W KI LC GV+GV A+
Sbjct: 241 LWLIP-ITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTAL 280
>gi|169212904 PREDICTED: acyl-malonyl condensing enzyme 1-like 1
[Homo sapiens]
Length = 338
Score = 29.3 bits (64), Expect = 8.1
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 17/76 (22%)
Query: 377 VAIALILLVLVNV-LVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLR--IVPSEVEPFL 433
+A++L LLV ++ C+PT+ + G++G L+ +P +F L+ ++PS++ L
Sbjct: 201 LALSLGLLVYRSLHFPSCLPTVAFLSGLVG------LLGSVPGLFVLQTPVLPSDL---L 251
Query: 434 SWPKIQALCFGVLGVL 449
SW C G +G+L
Sbjct: 252 SWS-----CVGTVGIL 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,659,009
Number of Sequences: 37866
Number of extensions: 701453
Number of successful extensions: 2259
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2185
Number of HSP's gapped (non-prelim): 42
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.