Guide to the Human Genome
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Search of human proteins with 10518338

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10518338 crystallin, gamma C [Homo sapiens]
         (174 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10518338 crystallin, gamma C [Homo sapiens]                        375   e-104
gi|148491074 crystallin, gamma B [Homo sapiens]                       303   4e-83
gi|148491057 crystallin, gamma A [Homo sapiens]                       290   3e-79
gi|13377002 crystallin, gamma D [Homo sapiens]                        273   5e-74
gi|8922120 crystallin, gamma S [Homo sapiens]                         207   4e-54
gi|89886227 absent in melanoma 1-like [Homo sapiens]                  123   9e-29
gi|12056461 crystallin, beta A3 [Homo sapiens]                        118   3e-27
gi|4758074 crystallin, beta B3 [Homo sapiens]                         118   3e-27
gi|4503063 crystallin, beta B2 [Homo sapiens]                         114   4e-26
gi|4503061 crystallin, beta B1 [Homo sapiens]                         112   2e-25
gi|4503059 crystallin, beta A4 [Homo sapiens]                         110   8e-25
gi|16936542 crystallin, beta A2 [Homo sapiens]                         99   2e-21
gi|16936540 crystallin, beta A2 [Homo sapiens]                         99   2e-21
gi|7019357 crystallin, beta A2 [Homo sapiens]                          99   2e-21
gi|21389517 gammaN-crystallin [Homo sapiens]                           95   3e-20
gi|62988361 absent in melanoma 1 [Homo sapiens]                        86   1e-17
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi...    81   4e-16
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b...    30   1.4  
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]            28   4.0  
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]             28   4.0  
gi|188595677 integrin, beta 2 precursor [Homo sapiens]                 28   5.2  
gi|89191865 integrin, beta 2 precursor [Homo sapiens]                  28   5.2  
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]      27   6.8  
gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]       27   6.8  

>gi|10518338 crystallin, gamma C [Homo sapiens]
          Length = 174

 Score =  375 bits (963), Expect = e-104
 Identities = 174/174 (100%), Positives = 174/174 (100%)

Query: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
Sbjct: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60

Query: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120
           GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
Sbjct: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120

Query: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY 174
           IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
Sbjct: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY 174


>gi|148491074 crystallin, gamma B [Homo sapiens]
          Length = 175

 Score =  303 bits (777), Expect = 4e-83
 Identities = 138/175 (78%), Positives = 158/175 (90%), Gaps = 1/175 (0%)

Query: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           MGKITFYEDRAFQGRSYE TTDCPNLQPYFSRCNSIRVESGCWM+YERPNYQG QY LRR
Sbjct: 1   MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR 60

Query: 61  GEYPDYQQWMGLSDSIRSCCLI-PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLS 119
           GEYPDYQQWMGLSDSIRSCCLI P + ++R+++Y+R++ +G M EL++DC S+QDRFHL+
Sbjct: 61  GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT 120

Query: 120 EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY 174
           EI SL+VLEG W+LYE+PNYRGRQYLLRP EYRR  DWGA +AK GSLRRV+DLY
Sbjct: 121 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY 175


>gi|148491057 crystallin, gamma A [Homo sapiens]
          Length = 174

 Score =  290 bits (743), Expect = 3e-79
 Identities = 130/174 (74%), Positives = 147/174 (84%)

Query: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           MGKITFYEDR FQGR Y   +DCPNL+ YFSRCNSIRV+SGCWMLYERPNYQG QY LRR
Sbjct: 1   MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60

Query: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120
           G+YPDYQ WMGLSDS++SC +IP T SH+LRLYER+D++GLM EL++DC  + + F L E
Sbjct: 61  GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120

Query: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY 174
           I SLHVLEGCWVLYE+PNYRGRQYLLRP +YRR  DWG  DAK GSLRRV DLY
Sbjct: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY 174


>gi|13377002 crystallin, gamma D [Homo sapiens]
          Length = 174

 Score =  273 bits (698), Expect = 5e-74
 Identities = 124/172 (72%), Positives = 144/172 (83%)

Query: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           MGKIT YEDR FQGR YE ++D PNLQPY SRCNS RV+SGCWMLYE+PNY G QY LRR
Sbjct: 1   MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60

Query: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120
           G+Y D+QQWMGLSDS+RSC LIP + SHR+RLYERED++G M+E +EDC  +QDRF  +E
Sbjct: 61  GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120

Query: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172
           I SL+VLEG WVLYEL NYRGRQYLL P +YRR QDWGA +A+ GSLRRV+D
Sbjct: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172


>gi|8922120 crystallin, gamma S [Homo sapiens]
          Length = 178

 Score =  207 bits (527), Expect = 4e-54
 Identities = 92/172 (53%), Positives = 121/172 (70%), Gaps = 2/172 (1%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGE 62
           KITFYED+ FQGR Y+   DC +   Y SRCNSI+VE G W +YERPN+ G  Y+L +GE
Sbjct: 7   KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66

Query: 63  YPDYQQWMGLSDSIRSCCLI--PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120
           YP+YQ+WMGL+D + SC  +  P    ++++++E+ D  G M E +EDCPSI ++FH+ E
Sbjct: 67  YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126

Query: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172
           I S  VLEG W+ YELPNYRGRQYLL  +EYR+  DWGA      S RR+V+
Sbjct: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178


>gi|89886227 absent in melanoma 1-like [Homo sapiens]
          Length = 616

 Score =  123 bits (308), Expect = 9e-29
 Identities = 64/175 (36%), Positives = 97/175 (55%), Gaps = 8/175 (4%)

Query: 7   YEDRAFQGRSYETTTDCPNLQ-------PYFSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
           YE   FQGRS+E + D  NLQ       P+ +   S+RV  GCW+ YE+  ++G QYLL 
Sbjct: 128 YEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLE 187

Query: 60  RGEYPDYQQWMGLSDSIRSCCLIPQTVSH-RLRLYEREDHKGLMMELSEDCPSIQDRFHL 118
            GEYPD+  W G  + + S  +I        + L+E  D +G  +E+S+  P ++   H 
Sbjct: 188 EGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEVSKALPDVELVQHG 247

Query: 119 SEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDL 173
              +++HVL G WV Y+   + G QY+L    YR C+DWGA ++   SL+ V+ +
Sbjct: 248 PSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQV 302



 Score = 88.2 bits (217), Expect = 3e-18
 Identities = 56/180 (31%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPYFS--RCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           +I+ + +   +G   + T    N Q      +  S  V +G W+LY +P ++   Y+L  
Sbjct: 29  EISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEP 88

Query: 61  GEYPDYQQWMGLSDSIRS-------CCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQ 113
           GEYP  + W     S+ S       C  + +    R  +YE    +G   E+S D  ++Q
Sbjct: 89  GEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQ 148

Query: 114 -----DRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLR 168
                   HL+ + SL VL GCWV YE   +RG QYLL   EY     WG  D    SLR
Sbjct: 149 QPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLR 208



 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 42/176 (23%), Positives = 82/176 (46%), Gaps = 12/176 (6%)

Query: 4   ITFYEDRAFQGRSYETTTDCPNLQ--PYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           +  +E   F+G   E +   P+++   +     +I V SG W+ Y+   + G+QY+L +G
Sbjct: 219 VVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKG 278

Query: 62  EYPDYQQWMGLSDSIRSCCLIPQTVSH------RLRLYEREDHKGLMMELSEDCPSIQDR 115
            Y + + W   + ++ S   + Q   H      +++L+ R D  G      +D  ++   
Sbjct: 279 VYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPAS 338

Query: 116 FHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKA-GSLRRV 170
           F     +S  V  G W+L++  N+ G Q++L   E+      G + +   GSL++V
Sbjct: 339 F---RPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKV 391



 Score = 63.9 bits (154), Expect = 7e-11
 Identities = 45/151 (29%), Positives = 71/151 (47%), Gaps = 9/151 (5%)

Query: 1   MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           + KI  +    F G  +    D   L   F R  S RV  G W+L++  N++G Q++L  
Sbjct: 310 VSKIQLFSRPDFLGDHFSFEDDQAALPASF-RPQSCRVHGGSWILFDETNFEGDQHILSE 368

Query: 61  GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLR-----LYEREDHKGLMMELSEDCPSIQDR 115
           GE+P       L+ ++       Q VS         LY  E  +G  +ELS +  S+Q  
Sbjct: 369 GEFPTLTAMGCLASTVLGSL---QKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAE 425

Query: 116 FHLSEIRSLHVLEGCWVLYELPNYRGRQYLL 146
              + + S+ +  G WVL E  ++RGRQ+L+
Sbjct: 426 GFNNHVLSVRIKGGIWVLCEHSDFRGRQWLV 456



 Score = 35.8 bits (81), Expect = 0.019
 Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 4   ITFYEDRAFQGRSYETTTDCPNLQP--YFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           I  Y    F+G+  E + +  +LQ   + +   S+R++ G W+L E  +++G+Q+L+   
Sbjct: 400 IFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSC 459

Query: 62  EYPDYQQWMG 71
           E  ++  + G
Sbjct: 460 EITNWLTYSG 469


>gi|12056461 crystallin, beta A3 [Homo sapiens]
          Length = 215

 Score =  118 bits (295), Expect = 3e-27
 Identities = 65/183 (35%), Positives = 103/183 (56%), Gaps = 16/183 (8%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           KIT Y+   FQG+  E T+ CPN+ +  F    S++VESG W+ YE  ++ GQQ++L RG
Sbjct: 32  KITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERG 91

Query: 62  EYPDYQQWMGLSD-------SIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQD 114
           EYP +  W G +        S R  C      S ++ ++E+E+  G   E+S+D PS+Q 
Sbjct: 92  EYPRWDAWSGSNAYHIERLMSFRPICSANHKES-KMTIFEKENFIGRQWEISDDYPSLQA 150

Query: 115 R-FHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ----EYRRCQDWG--AMDAKAGSL 167
             +  +E+ S+ +  G WV Y+ P YRG QY+L       +Y+  ++WG  A  ++  S+
Sbjct: 151 MGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSI 210

Query: 168 RRV 170
           RR+
Sbjct: 211 RRI 213


>gi|4758074 crystallin, beta B3 [Homo sapiens]
          Length = 211

 Score =  118 bits (295), Expect = 3e-27
 Identities = 61/175 (34%), Positives = 92/175 (52%), Gaps = 5/175 (2%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           K+  YE   FQG+  E + +CP+L      +  SI+VESG W+ +E   ++G+Q++L +G
Sbjct: 25  KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84

Query: 62  EYPDYQQWMGLSDSIRSCCLIPQTVS---HRLRLYEREDHKGLMMEL-SEDCPSIQDRFH 117
           +YP +  W    DS     L P  +    H+L L+E     G  ME+  +D PS+     
Sbjct: 85  DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144

Query: 118 LSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172
              + S+  + G WV YE P YRGRQY+    EYR   +W A   +  S+RR+ D
Sbjct: 145 QDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199



 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 87  SHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLL 146
           S+++ LYE E+ +G   ELS +CPS+ D   L ++ S+ V  G W+ +E   +RG Q++L
Sbjct: 23  SYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFVL 81

Query: 147 RPQEYRRCQDW 157
              +Y R   W
Sbjct: 82  EKGDYPRWDAW 92


>gi|4503063 crystallin, beta B2 [Homo sapiens]
          Length = 205

 Score =  114 bits (285), Expect = 4e-26
 Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 5/176 (2%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           KI  +E   FQG S+E    CPNL+     +  S+ V++G W+ YE+ N +G+Q++  +G
Sbjct: 18  KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77

Query: 62  EYPDYQQWMGL--SDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMEL-SEDCPSIQDRFH 117
           EYP +  W     +DS+ S   I   +  H++ LYE  +  G  ME+  +D PS     +
Sbjct: 78  EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137

Query: 118 LSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDL 173
             ++ S+ V  G WV Y+ P YRG QYLL   +Y+   D+GA   +  S+RR+ D+
Sbjct: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDM 193



 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 1/75 (1%)

Query: 83  PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGR 142
           PQ+++ ++ ++E+E+ +G   EL+  CP++++   + +  S+ V  G WV YE  N +G 
Sbjct: 12  PQSLNPKIIIFEQENFQGHSHELNGPCPNLKET-GVEKAGSVLVQAGPWVGYEQANCKGE 70

Query: 143 QYLLRPQEYRRCQDW 157
           Q++    EY R   W
Sbjct: 71  QFVFEKGEYPRWDSW 85


>gi|4503061 crystallin, beta B1 [Homo sapiens]
          Length = 252

 Score =  112 bits (279), Expect = 2e-25
 Identities = 61/175 (34%), Positives = 93/175 (53%), Gaps = 5/175 (2%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           ++  +E   FQGR  E + +C NL    F R  SI V +G W+ +E+ N++G+ ++L +G
Sbjct: 60  RLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKG 119

Query: 62  EYPDYQQWMGLSDSIRSCCLIP---QTVSHRLRLYEREDHKGLMMELS-EDCPSIQDRFH 117
           EYP +  W     S R     P       H++ L+E  + KG  +E+  +D PS+     
Sbjct: 120 EYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGF 179

Query: 118 LSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172
              + S+ V  G WV Y+ P YRG QYLL P ++R   +WGA   +  SLRR+ D
Sbjct: 180 SDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRD 234


>gi|4503059 crystallin, beta A4 [Homo sapiens]
          Length = 196

 Score =  110 bits (274), Expect = 8e-25
 Identities = 65/182 (35%), Positives = 102/182 (56%), Gaps = 14/182 (7%)

Query: 3   KITFYEDRAFQGRSYETTTDCPN-LQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           K+  +++  FQGR +E T +CP+ L+  F    S++V SG W+ +E   +QGQQY+L RG
Sbjct: 13  KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72

Query: 62  EYPDYQQWMGLS--DSIRSCCLIPQTVSH----RLRLYEREDHKGLMMELSEDCPSIQDR 115
           EYP +  W G +   + R     P   ++    RL ++E+E+  G   ELS+D PS+Q  
Sbjct: 73  EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAM 132

Query: 116 -FHLSEIRSLHVLEGCWVLYELPNYRGRQYLL----RPQEYRRCQDWG--AMDAKAGSLR 168
            +  +E+ S HV  G WV  + P YRG QY+L       +Y+  ++WG  A   +  S+R
Sbjct: 133 GWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIR 192

Query: 169 RV 170
           R+
Sbjct: 193 RI 194


>gi|16936542 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score = 98.6 bits (244), Expect = 2e-21
 Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 9/152 (5%)

Query: 4   ITFYEDRAFQGRSYETTTDCPNL--QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           +T +++  FQGR     +DC N+  +    R  S++VE+G W+ +E P++QGQQ++L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  EYPDYQQWMGLSDSIRSCCLIPQTV------SHRLRLYEREDHKGLMMELSEDCPSIQDR 115
           +YP +  W G S    +  L  + V        R+ L+E ++ +G   +L +D PS+   
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 FHLS-EIRSLHVLEGCWVLYELPNYRGRQYLL 146
              S ++ SL V  G WV Y+ P YRG QY+L
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 24/68 (35%), Positives = 40/68 (58%)

Query: 90  LRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ 149
           L L++ ED +G    L  DC ++ +R  L  +RS+ V  G WV +E P+++G+Q++L   
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 150 EYRRCQDW 157
           +Y R   W
Sbjct: 74  DYPRWSAW 81



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY---FSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
           ++T +E   FQG  ++   D P+L           S++V SG W+ Y+ P Y+G QY+L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  R----GEYPDY 66
           R    GE+  Y
Sbjct: 167 RDRHSGEFCTY 177


>gi|16936540 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score = 98.6 bits (244), Expect = 2e-21
 Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 9/152 (5%)

Query: 4   ITFYEDRAFQGRSYETTTDCPNL--QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           +T +++  FQGR     +DC N+  +    R  S++VE+G W+ +E P++QGQQ++L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  EYPDYQQWMGLSDSIRSCCLIPQTV------SHRLRLYEREDHKGLMMELSEDCPSIQDR 115
           +YP +  W G S    +  L  + V        R+ L+E ++ +G   +L +D PS+   
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 FHLS-EIRSLHVLEGCWVLYELPNYRGRQYLL 146
              S ++ SL V  G WV Y+ P YRG QY+L
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 24/68 (35%), Positives = 40/68 (58%)

Query: 90  LRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ 149
           L L++ ED +G    L  DC ++ +R  L  +RS+ V  G WV +E P+++G+Q++L   
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 150 EYRRCQDW 157
           +Y R   W
Sbjct: 74  DYPRWSAW 81



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY---FSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
           ++T +E   FQG  ++   D P+L           S++V SG W+ Y+ P Y+G QY+L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  R----GEYPDY 66
           R    GE+  Y
Sbjct: 167 RDRHSGEFCTY 177


>gi|7019357 crystallin, beta A2 [Homo sapiens]
          Length = 197

 Score = 98.6 bits (244), Expect = 2e-21
 Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 9/152 (5%)

Query: 4   ITFYEDRAFQGRSYETTTDCPNL--QPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61
           +T +++  FQGR     +DC N+  +    R  S++VE+G W+ +E P++QGQQ++L +G
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 62  EYPDYQQWMGLSDSIRSCCLIPQTV------SHRLRLYEREDHKGLMMELSEDCPSIQDR 115
           +YP +  W G S    +  L  + V        R+ L+E ++ +G   +L +D PS+   
Sbjct: 74  DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133

Query: 116 FHLS-EIRSLHVLEGCWVLYELPNYRGRQYLL 146
              S ++ SL V  G WV Y+ P YRG QY+L
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 24/68 (35%), Positives = 40/68 (58%)

Query: 90  LRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQ 149
           L L++ ED +G    L  DC ++ +R  L  +RS+ V  G WV +E P+++G+Q++L   
Sbjct: 14  LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73

Query: 150 EYRRCQDW 157
           +Y R   W
Sbjct: 74  DYPRWSAW 81



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY---FSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
           ++T +E   FQG  ++   D P+L           S++V SG W+ Y+ P Y+G QY+L 
Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166

Query: 60  R----GEYPDY 66
           R    GE+  Y
Sbjct: 167 RDRHSGEFCTY 177


>gi|21389517 gammaN-crystallin [Homo sapiens]
          Length = 182

 Score = 95.1 bits (235), Expect = 3e-20
 Identities = 47/117 (40%), Positives = 68/117 (58%), Gaps = 3/117 (2%)

Query: 2   GKITFYEDRAFQGRSYETTTDCPNLQP--YFSRCNSIRVESGCWMLYERPNYQGQQYLLR 59
           GKIT YE + F G+  E   DC N Q   + +R NSI VESG W+ +  P+++GQQ++L 
Sbjct: 6   GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65

Query: 60  RGEYPDYQQWMGLSDSIRSCCLIPQTVSH-RLRLYEREDHKGLMMELSEDCPSIQDR 115
            G+YPD+ +W   SD + SC  +     H RL ++E  +  G  +E  ED P +Q R
Sbjct: 66  HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122



 Score = 60.5 bits (145), Expect = 7e-10
 Identities = 28/84 (33%), Positives = 46/84 (54%)

Query: 87  SHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLL 146
           S ++ LYE +   G  +E+  DC + QDR  ++ + S+HV  G WV +  P++RG+Q++L
Sbjct: 5   SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64

Query: 147 RPQEYRRCQDWGAMDAKAGSLRRV 170
              +Y     W +     GS R V
Sbjct: 65  EHGDYPDFFRWNSHSDHMGSCRPV 88


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 86.3 bits (212), Expect = 1e-17
 Identities = 58/172 (33%), Positives = 86/172 (50%), Gaps = 6/172 (3%)

Query: 3    KITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGE 62
            +I  + +  FQG S         +   FS   S RV  G W++Y+  N+ G QY+L  G 
Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFST-KSCRVSGGSWVVYDGENFTGNQYVLEEGH 1474

Query: 63   YPDYQQWMGLSD--SIRSCCLIPQTVSH-RLRLYEREDHKGLMMELSEDCPSIQDRFHLS 119
            YP     MG     + +S   I    S   + L+ERED KG  +EL+ +  +++     +
Sbjct: 1475 YPCLSA-MGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETVNLRSLGFNT 1533

Query: 120  EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVV 171
            +IRS+ V+ G WV YE  +YRGRQ+LL P E     ++     + GSLR  V
Sbjct: 1534 QIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGC-RQIGSLRPFV 1584



 Score = 85.9 bits (211), Expect = 2e-17
 Identities = 52/185 (28%), Positives = 89/185 (48%), Gaps = 17/185 (9%)

Query: 3    KITFYEDRAFQGRSYETTTDCPNLQPY--------------FSRCNSIRVESGCWMLYER 48
            K+  YE   F+G+  E  T   +                  F+   S++V  G W+ YE+
Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEK 1278

Query: 49   PNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS--HRLRLYERE-DHKGLMMEL 105
            P + G QYLL  GEY D++ W G +  ++S   I    S  H +   E+    KG  +++
Sbjct: 1279 PGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSIDV 1338

Query: 106  SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAG 165
                 ++++  +  + +S++VL G WV YE P++ G QY+L    Y   +DWG  + K  
Sbjct: 1339 LGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNCKIS 1398

Query: 166  SLRRV 170
            S++ +
Sbjct: 1399 SVQPI 1403



 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 19/156 (12%)

Query: 35   SIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQW---MGLSDSIRSCCLIPQTVSH--- 88
            S++V  G W++YE P +QG  ++L  GEYPD   W        S+R   +  + V     
Sbjct: 1158 SMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGSMRPLKMGGRKVEFPTD 1217

Query: 89   -RLRLYEREDHKGLMMELSEDCPSI------------QDRFHLSEIRSLHVLEGCWVLYE 135
             ++ +YE+   +G  +EL     S              D    + + S+ VL G WV YE
Sbjct: 1218 PKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYE 1277

Query: 136  LPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVV 171
             P + G QYLL   EYR  + WG  + +  SLR ++
Sbjct: 1278 KPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPIL 1313



 Score = 67.0 bits (162), Expect = 8e-12
 Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 21/185 (11%)

Query: 2    GKITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
            GK+  Y +     +  E  +D  +   +  S    I+V  GCW+LYE+PN++G    L  
Sbjct: 1022 GKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEE 1081

Query: 61   GEYPDYQQWMGLSD-----------------SIRSCCLIPQTVSHRLRLYEREDHKGLMM 103
            GE      W G+ D                 SIR   +    VSH + L+   +  G++ 
Sbjct: 1082 GELELSGLW-GIEDILERHEEAESDKPVVIGSIRHV-VQDYRVSH-IDLFTEPEGLGILS 1138

Query: 104  ELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAK 163
               +D   +Q    + +  S+ V  G W++YE P ++G  ++L P EY     W    A 
Sbjct: 1139 SYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAY 1198

Query: 164  AGSLR 168
             GS+R
Sbjct: 1199 IGSMR 1203


>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
           sapiens]
          Length = 1022

 Score = 81.3 bits (199), Expect = 4e-16
 Identities = 50/176 (28%), Positives = 88/176 (50%), Gaps = 8/176 (4%)

Query: 3   KITFYEDRAFQGRSYETTTDCPNLQPY------FSRCNSIRVESGCWMLYERPNYQGQQY 56
           K+  YE   F G++ E +    ++  +      F R  SIRV  G W+ YE+ +++GQQ+
Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591

Query: 57  LLRRGEYPDYQQWMGLSDSIRSC-CLIPQTVSHRLRLYEREDHKGLMMEL-SEDCPSIQD 114
           LL  G++ D      LS  I S   L    +   + L+E +   G  +++ +++   +++
Sbjct: 592 LLEEGDFEDSNACGALSSPILSFRYLQANFIESSVTLFESDLESGKFIDITNQEISDLEE 651

Query: 115 RFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRV 170
               S+ RS+HV  G WV Y+   + G QY+L   +Y+   DWG  +    S+R +
Sbjct: 652 IGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPI 707



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 13/176 (7%)

Query: 4   ITFYEDRAFQGRSYETTT-DCPNLQP--YFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60
           +T +E     G+  + T  +  +L+   + S+  SI V+SG W+ Y++  + G+QY+L +
Sbjct: 626 VTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEK 685

Query: 61  GEYPDYQQWMGLSD---SIRSCCLIPQTVS---HRLRLYEREDHKGLMMELSEDCPSIQD 114
           G+Y  +  W G ++   SIR   L P  ++   H L+ + +   +G  ++ +E+   +  
Sbjct: 686 GKYKCFFDWGGSNNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEETSDLTS 745

Query: 115 RFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRV 170
               S      VL GCW+LY   +      +L    Y      G   +K  SL+ +
Sbjct: 746 LMPCS----FKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPASKVKSLKPI 797



 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 48/163 (29%), Positives = 70/163 (42%), Gaps = 14/163 (8%)

Query: 12  FQGRSY---ETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQ 68
           FQG      E T+D  +L P      S +V  GCW+LY + +      +L  G Y D   
Sbjct: 729 FQGECIDFTEETSDLTSLMPC-----SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTS 783

Query: 69  WMGLSDSIRSCCLIPQTVSH-RLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVL 127
               +  ++S   I        + L+  E  +G  + L E   S+ ++      +S+ V 
Sbjct: 784 CGCPASKVKSLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVK 843

Query: 128 EGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMD--AKAGSLR 168
            G W+ YE  N+ GRQ LLRP E     +W A       GSLR
Sbjct: 844 SGLWIAYEGSNFLGRQILLRPNE---IPNWTAFSRWKTIGSLR 883



 Score = 51.2 bits (121), Expect = 4e-07
 Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 8/153 (5%)

Query: 24  PNLQPY-FSRCNSIRVESGCWMLYERPNYQGQQYLLRRGE---YPDYQQWMGLSDSIRSC 79
           PNL+    S+  S  V+SG W+ Y   N++GQ  +L            +   L       
Sbjct: 463 PNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEEDHGLFEISTAEMKSLHPLQMGG 522

Query: 80  CLIPQTVSHRLRLYEREDHKGLMMELSEDCPSI----QDRFHLSEIRSLHVLEGCWVLYE 135
             +   ++ ++ +YE+    G   E SE   S+    ++      I S+ V+ G WV YE
Sbjct: 523 LKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYE 582

Query: 136 LPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLR 168
             +++G+Q+LL   ++      GA+ +   S R
Sbjct: 583 KEHFKGQQFLLEEGDFEDSNACGALSSPILSFR 615



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 36  IRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQW-------------MGLSDSIRSCCLI 82
           I+V  GCW+LYE+P+++GQ+ +L  GE    + W             +G    +   C I
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSI 440

Query: 83  PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGR 142
           P+     + L+ + D     + +    P++++  ++S+  S  V  G W+ Y   N++G+
Sbjct: 441 PE-----IELFPQSDPACCPVYIQRAVPNLEE-LNISKSVSFTVKSGVWLAYPDINFKGQ 494

Query: 143 QYLL 146
             +L
Sbjct: 495 ATVL 498



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 7/55 (12%)

Query: 124 LHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAK-------AGSLRRVV 171
           + V+ GCW+LYE P++RG++ +L   E    +DW   + +        GSL+RV+
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVL 435


>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
           [Homo sapiens]
          Length = 416

 Score = 29.6 bits (65), Expect = 1.4
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 8/63 (12%)

Query: 74  DSIRSCCLIPQTV-SHRLRLYEREDHKGLMM-------ELSEDCPSIQDRFHLSEIRSLH 125
           D + +  ++ + V SHRL ++ + D KG  +       E ++D P+ +D   L+E + LH
Sbjct: 192 DGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLH 251

Query: 126 VLE 128
           V E
Sbjct: 252 VGE 254


>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 88  HRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGC 130
           H++ L   EDH+        DCP  Q  F    I ++H+L+ C
Sbjct: 141 HKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHI-NIHILKDC 182


>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 88  HRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGC 130
           H++ L   EDH+        DCP  Q  F    I ++H+L+ C
Sbjct: 141 HKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHI-NIHILKDC 182


>gi|188595677 integrin, beta 2 precursor [Homo sapiens]
          Length = 769

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 128 EGCWVLYELPNYRGR-QYLLRPQEYRRC 154
           EGCWV Y L    G  +YL+   E R C
Sbjct: 668 EGCWVAYTLEQQDGMDRYLIYVDESREC 695


>gi|89191865 integrin, beta 2 precursor [Homo sapiens]
          Length = 769

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 128 EGCWVLYELPNYRGR-QYLLRPQEYRRC 154
           EGCWV Y L    G  +YL+   E R C
Sbjct: 668 EGCWVAYTLEQQDGMDRYLIYVDESREC 695


>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 1063

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 12/22 (54%), Positives = 16/22 (72%)

Query: 143 QYLLRPQEYRRCQDWGAMDAKA 164
           +YLL+ Q + RCQ+ GA  AKA
Sbjct: 473 EYLLKNQWFVRCQEMGARAAKA 494


>gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]
          Length = 1142

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 14/53 (26%), Positives = 26/53 (49%)

Query: 72  LSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSL 124
           LS    + C+  + +++   +Y    +K     +S+ C ++ DR  LS I SL
Sbjct: 771 LSSLFNTICMSGEMLANFRNIYRLSQNKTCKKHISQSCWTVHDRTLLSVIDSL 823


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.458 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,980,425
Number of Sequences: 37866
Number of extensions: 307557
Number of successful extensions: 770
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 646
Number of HSP's gapped (non-prelim): 48
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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