Guide to the Human Genome
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Search of human proteins with 183227703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|183227703 mitochondrial translation optimization 1 homolog
isoform c [Homo sapiens]
         (732 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183227703 mitochondrial translation optimization 1 homolog is...  1463   0.0  
gi|74024895 mitochondrial translation optimization 1 homolog iso...  1363   0.0  
gi|19882217 mitochondrial translation optimization 1 homolog iso...  1349   0.0  
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          35   0.19 
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]          35   0.19 
gi|5454102 transforming, acidic coiled-coil containing protein 3...    35   0.25 
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.55 
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.55 
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.55 
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai...    33   0.94 
gi|23943928 hypothetical protein LOC140680 [Homo sapiens]              33   1.2  
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    32   1.6  
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    32   1.6  
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom...    32   2.1  
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap...    32   2.7  
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    31   3.6  
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    31   3.6  
gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type ...    31   3.6  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           31   4.7  
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]            31   4.7  
gi|119709832 low density lipoprotein receptor-related protein 5 ...    31   4.7  
gi|156416003 succinate dehydrogenase complex, subunit A, flavopr...    31   4.7  
gi|4504383 HGF activator preproprotein [Homo sapiens]                  31   4.7  
gi|4557735 monoamine oxidase A [Homo sapiens]                          30   6.1  
gi|26051271 voltage-gated potassium channel, subfamily H, member...    30   6.1  
gi|4557729 voltage-gated potassium channel, subfamily H, member ...    30   6.1  
gi|50301238 glutathione reductase [Homo sapiens]                       30   6.1  
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]           30   8.0  
gi|19923899 coiled-coil domain containing 45 [Homo sapiens]            30   8.0  

>gi|183227703 mitochondrial translation optimization 1 homolog
           isoform c [Homo sapiens]
          Length = 732

 Score = 1463 bits (3787), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420
           MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ
Sbjct: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420

Query: 421 TECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVIAGINASLRVSRKPPFVV 480
           TECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVIAGINASLRVSRKPPFVV
Sbjct: 421 TECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVIAGINASLRVSRKPPFVV 480

Query: 481 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 540
           SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR
Sbjct: 481 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 540

Query: 541 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 600
           YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS
Sbjct: 541 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 600

Query: 601 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 660
           LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR
Sbjct: 601 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 660

Query: 661 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 720
           DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY
Sbjct: 661 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 720

Query: 721 LCDADRLQEREL 732
           LCDADRLQEREL
Sbjct: 721 LCDADRLQEREL 732


>gi|74024895 mitochondrial translation optimization 1 homolog
           isoform a [Homo sapiens]
          Length = 692

 Score = 1363 bits (3527), Expect = 0.0
 Identities = 692/732 (94%), Positives = 692/732 (94%), Gaps = 40/732 (5%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQ 420
           MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAA 
Sbjct: 361 MITCIRGLEKAKVIQPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAA- 419

Query: 421 TECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVIAGINASLRVSRKPPFVV 480
                                                  QGVIAGINASLRVSRKPPFVV
Sbjct: 420 ---------------------------------------QGVIAGINASLRVSRKPPFVV 440

Query: 481 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 540
           SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR
Sbjct: 441 SRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQR 500

Query: 541 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 600
           YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS
Sbjct: 501 YERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDS 560

Query: 601 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 660
           LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR
Sbjct: 561 LAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIR 620

Query: 661 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 720
           DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY
Sbjct: 621 DVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQY 680

Query: 721 LCDADRLQEREL 732
           LCDADRLQEREL
Sbjct: 681 LCDADRLQEREL 692


>gi|19882217 mitochondrial translation optimization 1 homolog
           isoform b [Homo sapiens]
          Length = 717

 Score = 1349 bits (3491), Expect = 0.0
 Identities = 692/757 (91%), Positives = 692/757 (91%), Gaps = 65/757 (8%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQ-------------------------PGYGVQYDYLDPRQITPSLE 395
           MITCIRGLEKAKVIQ                         PGYGVQYDYLDPRQITPSLE
Sbjct: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420

Query: 396 THLVQRLFFAGQINGTTGYEEAAAQTECCSVARLECSDMISQLQAILLPQPSLVAGTAGM 455
           THLVQRLFFAGQINGTTGYEEAAA                                    
Sbjct: 421 THLVQRLFFAGQINGTTGYEEAAA------------------------------------ 444

Query: 456 HHNTQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS 515
               QGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS
Sbjct: 445 ----QGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS 500

Query: 516 LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA 575
           LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA
Sbjct: 501 LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA 560

Query: 576 SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ 635
           SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ
Sbjct: 561 SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ 620

Query: 636 LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII 695
           LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII
Sbjct: 621 LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII 680

Query: 696 NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 732
           NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 681 NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 15/44 (34%), Positives = 27/44 (61%)

Query: 22  LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
           L +++     P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 148 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 191


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 15/44 (34%), Positives = 27/44 (61%)

Query: 22 LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          L +++     P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 50 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 93


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 8/79 (10%)

Query: 588 LDVLKYEEVDMDSLAKAVPEPLKKY-TKCREL----AERLKIEATYESVLFHQLQEI--- 639
           +D+L+Y + D+D++ KA  E  ++  ++C EL     E  KI   +E V++  ++E+   
Sbjct: 634 VDLLQYSQKDLDAVVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQ 693

Query: 640 KGVQQDEALQLPKDLDYLT 658
           K + + E  ++ K+ D LT
Sbjct: 694 KELSKAEIQKVLKEKDQLT 712


>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain
          2 [Homo sapiens]
          Length = 581

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)

Query: 8  GRWVAVSFTKQQFPLARLSSDSA-APRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLT 66
          GR +  +     FP  R  +  A     P +D +VIG GH G  AA    R G  T +  
Sbjct: 5  GRGLCKAVAASPFPAWRRDNTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFE 64

Query: 67 HR 68
           R
Sbjct: 65 RR 66


>gi|23943928 hypothetical protein LOC140680 [Homo sapiens]
          Length = 363

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 41/143 (28%), Positives = 60/143 (41%), Gaps = 43/143 (30%)

Query: 547 MKSSLEEGISVLKSIE----FLSSKWKKLIPEAS-ISTSRSLPVRAL-----------DV 590
           MK+SL  G + L+ +     FLS   ++LI     +  S +L VRAL           D+
Sbjct: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160

Query: 591 LKYEEVDMDSLAKAVPEPLKKYTKCR-----ELAERL--KIEATYESV------------ 631
           L+Y         K+  +  ++  KC+     + AE+L  KIE T E V            
Sbjct: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220

Query: 632 --------LFHQLQEIKGVQQDE 646
                   L  QLQ++K  QQDE
Sbjct: 221 IKSVQISTLMRQLQQVKDSQQDE 243


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 37/158 (23%), Positives = 77/158 (48%), Gaps = 20/158 (12%)

Query: 537 SQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEV 596
           +Q+ Y++    K  ++E    + S+E    ++++ + E S S  R L +    V KY  +
Sbjct: 322 AQKHYKKR---KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRL 378

Query: 597 DMDSLAKA--VPEPLKKYTKCR-------ELAERLKIEATYESVLFHQLQEIKGVQQDEA 647
             ++  +A  + + L+K+ + +       +L ER K+E   E+ +  +L+EI+  Q+   
Sbjct: 379 KEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVET--EAKIKQKLREIEENQK--- 433

Query: 648 LQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASR 685
            ++ K  +Y+T    SL  E ++KL     + +  A R
Sbjct: 434 -RIEKLEEYITTSKQSL--EEQKKLEGELTEEVEMAKR 468


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 3/48 (6%)

Query: 38  DVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIG 85
           DV+VIG G  G  AA   A+ G R L+L       G   C  +FG  G
Sbjct: 69  DVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGG---CCHTFGKNG 113


>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
           sapiens]
          Length = 486

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 25  LSSDSAAPRTPHFDVIVIGGGHAGTEAA----TAAARCGSRTLLLTHRVDTIGQMSCNPS 80
           L  D++     H DV+++GGG  G   A       +R G+  +L+  R  T  Q S   S
Sbjct: 52  LLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLS 111

Query: 81  FGGI 84
            GGI
Sbjct: 112 VGGI 115


>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
           sapiens]
          Length = 1025

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 13/30 (43%), Positives = 19/30 (63%)

Query: 39  VIVIGGGHAGTEAATAAARCGSRTLLLTHR 68
           VIV+G G    + AT+A RCG+R + +  R
Sbjct: 335 VIVLGAGDTAFDCATSALRCGARRVFIVFR 364


>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
           [Homo sapiens]
          Length = 727

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 20/64 (31%), Positives = 30/64 (46%)

Query: 34  TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
           T  FD++VIGGG  G+  A  A   G +T L+     + G  S +      G  +L + +
Sbjct: 67  TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126

Query: 94  DALD 97
             LD
Sbjct: 127 MKLD 130


>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
           [Homo sapiens]
          Length = 727

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 20/64 (31%), Positives = 30/64 (46%)

Query: 34  TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
           T  FD++VIGGG  G+  A  A   G +T L+     + G  S +      G  +L + +
Sbjct: 67  TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126

Query: 94  DALD 97
             LD
Sbjct: 127 MKLD 130


>gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type
           motif 17 [Homo sapiens]
          Length = 328

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 18  QQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSC 77
           Q+ P    ++    PR P  ++    G   G      ++    +T+LLT R  T+   S 
Sbjct: 64  QRPPFCPFAALEERPRVPGAELPTDRGVDLGVAVILQSS---DKTVLLTRRARTL---SV 117

Query: 78  NPSFGGIGKGHLMREVDALDGLCSRICDQSGVH 110
           +P+      GH+  E + LDG    + ++SG+H
Sbjct: 118 SPNLWVPPGGHVELEEELLDGGLRELWEESGLH 150


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 144  NTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVL---VDGSTVYAESVILTTGTFL 197
            N P+   QE +   +IL    P  TG C +SG  +    +GS ++ +SV  T  T+L
Sbjct: 2573 NRPI--AQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYL 2627


>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
          Length = 1289

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 144 NTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVL---VDGSTVYAESVILTTGTFL 197
           N P+   QE +   +IL    P  TG C +SG  +    +GS ++ +SV  T  T+L
Sbjct: 876 NRPI--AQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYL 930


>gi|119709832 low density lipoprotein receptor-related protein 5
           [Homo sapiens]
          Length = 1615

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 490 LIDDLTTLGTSEPYRMFTSRVEF-RLSLRPDNADSRLTLRGYKDAGCV 536
           L+ D+ T    E + +FTSR    R+SL  +N D  + L G K+A  +
Sbjct: 633 LLSDMKTCIVPEAFLVFTSRAAIHRISLETNNNDVAIPLTGVKEASAL 680


>gi|156416003 succinate dehydrogenase complex, subunit A,
           flavoprotein precursor [Homo sapiens]
          Length = 664

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 17/98 (17%)

Query: 27  SDSAAPRTP----HFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDT-----IGQMSC 77
           SDS + + P     FD +V+G G AG  AA   +  G  T  +T    T       Q   
Sbjct: 48  SDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGI 107

Query: 78  NPSFGGI----GKGHLMREVDALDGLCSRICDQSGVHY 111
           N + G +     + H    V   D L     DQ  +HY
Sbjct: 108 NAALGNMEEDNWRWHFYDTVKGSDWL----GDQDAIHY 141


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 591 LKYEEVDMDSLAKAVPEPLKKYTKCR--ELAERLKIEATYESVLFHQLQEIKGVQQDEAL 648
           L Y+E+ +DS+  A    L  +  CR  +  ER       +S L  +   ++  +    +
Sbjct: 314 LLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRV 373

Query: 649 QLPKDLDYLTIRDVSLSHEVREKLH----FSRPQTIGAASRIPGVTP 691
           QL  DL        S   +   + H    F RP+ IG +S +PG  P
Sbjct: 374 QLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP 420


>gi|4557735 monoamine oxidase A [Homo sapiens]
          Length = 527

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 37 FDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIG 73
          FDV+VIGGG +G  AA      G   L+L  R D +G
Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR-DRVG 49


>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
           isoform b [Homo sapiens]
          Length = 888

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 15/45 (33%), Positives = 23/45 (51%)

Query: 419 AQTECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVI 463
           ++  C SV R   +D I  ++A +LP P   A T  MH    G++
Sbjct: 272 SRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLL 316


>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
           isoform a [Homo sapiens]
          Length = 1159

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 15/45 (33%), Positives = 23/45 (51%)

Query: 419 AQTECCSVARLECSDMISQLQAILLPQPSLVAGTAGMHHNTQGVI 463
           ++  C SV R   +D I  ++A +LP P   A T  MH    G++
Sbjct: 272 SRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLL 316


>gi|50301238 glutathione reductase [Homo sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 30  AAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL-THRV-DTIGQMSCNP 79
           AA     +D +VIGGG  G  +A  AA  G+R  ++ +H++  T   + C P
Sbjct: 58  AAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVP 109


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 18/137 (13%)

Query: 551  LEEGISVLKSIEFLSSKWKKL----IPEASISTSRSL-----PVRALDVLKYEEVDMDSL 601
            L EG+ V K  E+  + W  L    + E      R+L     PVR L V  Y E  M + 
Sbjct: 1270 LYEGLKVAKE-EWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAF 1328

Query: 602  AKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYL---- 657
              ++  PL    K   L +R   E   ++ +F ++ E   ++   A++L K  D L    
Sbjct: 1329 KDSI--PLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIV 1386

Query: 658  --TIRDVSLSHEVREKL 672
               I++V++   V+E L
Sbjct: 1387 TAAIKEVAIEKAVKEIL 1403


>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
          Length = 821

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query: 626 ATYESVLFHQLQEIKGV---QQDEALQLPKDLDYLTIR--DVSLSHEVREKLHFSRPQTI 680
           A Y+S+L  ++ ++  +   Q+D+A  +   +D L +    VSLSH   E +     ++I
Sbjct: 38  ALYQSILGEKVPDLIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESI 97

Query: 681 GAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQERE 731
                I          LL ++  T+R     +E S+T+QY  ++DR +  E
Sbjct: 98  KNLLEI-------FDGLLEYL--TERISETSHEKSETEQYFKESDRGERLE 139


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,658,711
Number of Sequences: 37866
Number of extensions: 1226738
Number of successful extensions: 2723
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2700
Number of HSP's gapped (non-prelim): 35
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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