Search of human proteins with 169203154

Search of human proteins with 169203154

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]          740   0.0  
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]          368   e-102
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]          365   e-101
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   140   2e-33
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]    113   2e-25
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      113   3e-25
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]    104   1e-22
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]   102   5e-22
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]    94   2e-19
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]    91   2e-18
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                 87   3e-17
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]       83   3e-16
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...    83   3e-16
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...    81   1e-15
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...    80   3e-15
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]    76   4e-14
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...    75   7e-14
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...    75   7e-14
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]    67   2e-11
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]     66   5e-11
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]    64   2e-10
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...    63   5e-10
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...    55   1e-07
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...    52   1e-06
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...    50   3e-06
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...    50   4e-06
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...    44   2e-04
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...    35   0.079
gi|88853069 vitronectin precursor [Homo sapiens]                       35   0.10 
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   34   0.18 

>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score =  740 bits (1911), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MGSDLRVYNTVFSPDDWRGIQKWQEVRQSFVQKIGSMPAPSGREQVTSDLQRLRGMLTTG 60
           MGSDLRVYNTVFSPDDWRGIQKWQEVRQSFVQKIGSMPAPSGREQVTSDLQRLRGMLTTG
Sbjct: 1   MGSDLRVYNTVFSPDDWRGIQKWQEVRQSFVQKIGSMPAPSGREQVTSDLQRLRGMLTTG 60

Query: 61  WELPISSHRMVVTRQKRKYDDGDDNNDDYTMMQYLVTQLLLEQCSQISKADDSTWFIVEI 120
           WELPISSHRMVVTRQKRKYDDGDDNNDDYTMMQYLVTQLLLEQCSQISKADDSTWFIVEI
Sbjct: 61  WELPISSHRMVVTRQKRKYDDGDDNNDDYTMMQYLVTQLLLEQCSQISKADDSTWFIVEI 120

Query: 121 QQILLVFSLLYLTAQQQFPQESFPVKYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQN 180
           QQILLVFSLLYLTAQQQFPQESFPVKYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQN
Sbjct: 121 QQILLVFSLLYLTAQQQFPQESFPVKYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQN 180

Query: 181 FFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDN 240
           FFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDN
Sbjct: 181 FFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDN 240

Query: 241 SPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSS 300
           SPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSS
Sbjct: 241 SPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSS 300

Query: 301 FVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358
           FVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN
Sbjct: 301 FVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358


>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score =  368 bits (944), Expect = e-102
 Identities = 173/174 (99%), Positives = 174/174 (100%)

Query: 185 KDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 244
           +DQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY
Sbjct: 25  EDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 84

Query: 245 GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 304
           GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP
Sbjct: 85  GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 144

Query: 305 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358
           ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN
Sbjct: 145 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 198



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25
          MGSDLRVYNTVFSPDDWRGIQKWQE
Sbjct: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25


>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score =  365 bits (938), Expect = e-101
 Identities = 172/174 (98%), Positives = 173/174 (99%)

Query: 185 KDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 244
           +DQNYMPNLPQEDVDRATGKAFELWS ASALTFTRDFESEGDIILSFVFLADLHDNSPFY
Sbjct: 25  EDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFY 84

Query: 245 GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 304
           GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP
Sbjct: 85  GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 144

Query: 305 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358
           ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN
Sbjct: 145 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 198



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25
          MGSDLRVYNTVFSPDDWRGIQKWQE
Sbjct: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  140 bits (353), Expect = 2e-33
 Identities = 81/175 (46%), Positives = 98/175 (56%), Gaps = 45/175 (25%)

Query: 146 KYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQNFFGLKD------------------- 186
           KYLE  YYNLK++  Q+ ++R+S PV+EKLKQMQ FFGLK                    
Sbjct: 36  KYLEK-YYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGV 94

Query: 187 ------------------------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFE 222
                                   +NY P+LP+ DVD A  KAF+LWSN + LTFT+  E
Sbjct: 95  PDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSE 154

Query: 223 SEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 277
            + DI++SFV   D  DNSPF G  G LAHAF PGPGIGGD HFD DE  T +FR
Sbjct: 155 GQADIMISFV-RGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 208



 Score =  113 bits (282), Expect = 3e-25
 Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)

Query: 267 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 326
           D DE R   F+ +K+W VQ   +L GYP+D+YSSF FP  VK IDAA+ E++TGKT+FFV
Sbjct: 336 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 393

Query: 327 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 357
           AN+YWRYDE  +S+D GYPK+I  D PGI  K
Sbjct: 394 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 425


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score =  113 bits (283), Expect = 2e-25
 Identities = 66/187 (35%), Positives = 96/187 (51%), Gaps = 45/187 (24%)

Query: 146 KYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQNFFGLKDQ------------------ 187
           KYLEN YY+LK ++ Q  R++DS PV++K+++MQ F GL+                    
Sbjct: 36  KYLEN-YYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGV 94

Query: 188 -------------------------NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFE 222
                                    NY P+LP++ VD A  KA ++W   + LTF+R +E
Sbjct: 95  PDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYE 154

Query: 223 SEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHW 282
            E DI++SF  + +  D  PF G    LAHA+ PGPGI GD HFD+DE  TKD   +  +
Sbjct: 155 GEADIMISFA-VREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLF 213

Query: 283 VVQEDQL 289
           +V   ++
Sbjct: 214 LVAAHEI 220



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 44/113 (38%), Positives = 70/113 (61%), Gaps = 9/113 (7%)

Query: 250 LAHAFPPGPGIGGDVHFDNDETRTKD----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPE 305
           L  +F P    G D  +   E  +KD    F+ ++ W ++ +++ +GYPR +++   FP 
Sbjct: 328 LISSFWPSLPSGVDAAY---EVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHT-LGFPP 383

Query: 306 RVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPGISKK 357
            V+KIDAAI +K+  KT+FFV ++YWR+DE   S++ G+PK I +D PGI  K
Sbjct: 384 TVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSK 436


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  113 bits (282), Expect = 3e-25
 Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)

Query: 267 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 326
           D DE R   F+ +K+W VQ   +L GYP+D+YSSF FP  VK IDAA+ E++TGKT+FFV
Sbjct: 270 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 327

Query: 327 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 357
           AN+YWRYDE  +S+D GYPK+I  D PGI  K
Sbjct: 328 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 359



 Score =  112 bits (281), Expect = 4e-25
 Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 187 QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGH 246
           +NY P+LP+ DVD A  KAF+LWSN + LTFT+  E + DI++SFV   D  DNSPF G 
Sbjct: 53  ENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFV-RGDHRDNSPFDGP 111

Query: 247 DGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 277
            G LAHAF PGPGIGGD HFD DE  T +FR
Sbjct: 112 GGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 142


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score =  104 bits (259), Expect = 1e-22
 Identities = 72/194 (37%), Positives = 93/194 (47%), Gaps = 51/194 (26%)

Query: 129 LLYLTAQQQFPQESFPVK------YLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQNFF 182
           LL++   + FP  S          YLE  +Y L S   Q  R+  ++ ++EKLK+MQ FF
Sbjct: 12  LLHVQISKAFPVSSKEKNTKTVQDYLEK-FYQLPSNQYQSTRKNGTNVIVEKLKEMQRFF 70

Query: 183 GL-------------------------------------------KDQNYMPNLPQEDVD 199
           GL                                           + +NY P L + +V+
Sbjct: 71  GLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVE 130

Query: 200 RATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPG 259
           RA   AFELWS AS L FTR  + E DI ++F +  D  DNSPF G +G LAHAF PG G
Sbjct: 131 RAIKDAFELWSVASPLIFTRISQGEADINIAF-YQRDHGDNSPFDGPNGILAHAFQPGQG 189

Query: 260 IGGDVHFDNDETRT 273
           IGGD HFD +ET T
Sbjct: 190 IGGDAHFDAEETWT 203



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 54/83 (65%), Gaps = 4/83 (4%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           F+ +++W +    +L GYP+D+ S++ FP  V+ IDAA++ +   KT+FFV +++WRYD 
Sbjct: 344 FKGNQYWALSGYDILQGYPKDI-SNYGFPSSVQAIDAAVFYRS--KTYFFVNDQFWRYDN 400

Query: 336 NMQSVDAGYPKIIDD-LPGISKK 357
             Q ++ GYPK I    PGI  K
Sbjct: 401 QRQFMEPGYPKSISGAFPGIESK 423


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score =  102 bits (254), Expect = 5e-22
 Identities = 63/202 (31%), Positives = 102/202 (50%), Gaps = 52/202 (25%)

Query: 134 AQQQFPQESFPVKYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQNFFGLKDQ------ 187
           A+++   +    +YLE  YYNL+ ++ Q  R++DS+ +++K++ MQ F GL+        
Sbjct: 24  AKEEDSNKDLAQQYLEK-YYNLEKDVKQF-RRKDSNLIVKKIQGMQKFLGLEVTGKLDTD 81

Query: 188 -------------------------------------NYMPNLPQEDVDRATGKAFELWS 210
                                                NY P+LP++ VD A  KA ++W 
Sbjct: 82  TLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWE 141

Query: 211 NASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDG---CLAHAFPPGPGIGGDVHFD 267
             + LTF+R +E E DI++SF     + ++  FY  DG    LAHA+PPGPG+ GD+HFD
Sbjct: 142 EVTPLTFSRLYEGEADIMISFA----VKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFD 197

Query: 268 NDETRTKDFRSSKHWVVQEDQL 289
           +DE  T+D   +  ++V   +L
Sbjct: 198 DDEKWTEDASGTNLFLVAAHEL 219



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 35/83 (42%), Positives = 62/83 (74%), Gaps = 2/83 (2%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           F+ ++ W ++ +++ +GYPR +++   FP  ++KIDAA+ +K+  KT+FF A++YWR+DE
Sbjct: 354 FKGNEFWAIRGNEVQAGYPRGIHT-LGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDE 412

Query: 336 NMQSVDAGYPKII-DDLPGISKK 357
           N QS++ G+P++I DD PG+  K
Sbjct: 413 NSQSMEQGFPRLIADDFPGVEPK 435


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 45/84 (53%), Positives = 57/84 (67%), Gaps = 1/84 (1%)

Query: 187 QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGH 246
           QNY  +LP+  +D A  +AF LWS  + LTFTR +  + DI++ F  +A+  D  PF G 
Sbjct: 126 QNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFG-VAEHGDGYPFDGK 184

Query: 247 DGCLAHAFPPGPGIGGDVHFDNDE 270
           DG LAHAFPPGPGI GD HFD+DE
Sbjct: 185 DGLLAHAFPPGPGIQGDAHFDDDE 208


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 71/249 (28%), Positives = 115/249 (46%), Gaps = 67/249 (26%)

Query: 143 FPVKYLENCYYNLKSEINQIGRQRDSSPVLEKLKQMQNFFGLKDQ--------------- 187
           F  +YL + Y+   + +  I ++  +S + E+L++MQ+FFGL+                 
Sbjct: 38  FAERYLRSYYH--PTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPR 95

Query: 188 ----------------------------NYMPNLPQEDVDRATGKAFELWSNASALTFTR 219
                                       NY P++   +V++A  KAF++WS+ + L FTR
Sbjct: 96  CGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTR 155

Query: 220 DFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSS 279
             +   DI++SF  + +  D  PF G  G LAHAFPPGP  GGD HFD+DET T   +  
Sbjct: 156 LHDGIADIMISFG-IKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGY 214

Query: 280 KHWVVQEDQ----LLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
             ++V   +    L   + +D   + +FP         IY   TGK+HF +       D+
Sbjct: 215 NLFLVAAHEFGHSLGLDHSKDP-GALMFP---------IYTY-TGKSHFMLP------DD 257

Query: 336 NMQSVDAGY 344
           ++Q + + Y
Sbjct: 258 DVQGIQSLY 266



 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 36/83 (43%), Positives = 50/83 (60%), Gaps = 2/83 (2%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           FR  K W +    +L GYP+ + S    P+ VKKI AA++ +DTGKT  F  N+ WRYD+
Sbjct: 349 FRGRKFWALNGYDILEGYPKKI-SELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDD 407

Query: 336 NMQSVDAGYPKII-DDLPGISKK 357
               +D  YP++I +D PGI  K
Sbjct: 408 TNHIMDKDYPRLIEEDFPGIGDK 430


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 63/208 (30%), Positives = 99/208 (47%), Gaps = 56/208 (26%)

Query: 120 IQQILLVFSLLYLTAQQQFP-------QESFPVK--YLENCYYNLKSEINQIGRQRDSSP 170
           ++++LL+F L ++T    FP       +E+  +   YL N +Y+L+ E N + + ++ S 
Sbjct: 1   MKRLLLLF-LFFITFSSAFPLVRMTENEENMQLAQAYL-NQFYSLEIEGNHLVQSKNRSL 58

Query: 171 VLEKLKQMQNFFGL-----------------------------------------KDQNY 189
           + +K+++MQ FFGL                                         +  NY
Sbjct: 59  IDDKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTLPGWRKYNLTYRIINY 118

Query: 190 MPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY--GHD 247
            P++ +  VD A  +  E+WS  + L FT+  +   DI+++F     +H   P Y  G  
Sbjct: 119 TPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAF--RTRVHGRCPRYFDGPL 176

Query: 248 GCLAHAFPPGPGIGGDVHFDNDETRTKD 275
           G L HAFPPGPG+GGD HFD DE  TKD
Sbjct: 177 GVLGHAFPPGPGLGGDTHFDEDENWTKD 204



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/101 (36%), Positives = 61/101 (60%), Gaps = 4/101 (3%)

Query: 258 PGIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIY 315
           P +  D+   ++N   +   F+    W+++   +L  YP+ +++   FP RVKKIDAA+ 
Sbjct: 323 PSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDYPKSIHT-LGFPGRVKKIDAAVC 381

Query: 316 EKDTGKTHFFVANEYWRYDENMQSVDAGYP-KIIDDLPGIS 355
           +K T KT+FFV    WR+DE  Q++D G+P +++   PGIS
Sbjct: 382 DKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGIS 422


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 52/141 (36%), Positives = 75/141 (53%), Gaps = 17/141 (12%)

Query: 189 YMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDG 248
           Y P+L  E VD A  +AF++WS+ + L F+R  + E DI+++F    +  D  PF G DG
Sbjct: 81  YTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRW-EHGDGYPFDGKDG 139

Query: 249 CLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---GYPRDVYSSFVFPE 305
            LAHAF PG G+GGD HFD+DE           W + E Q++    G     Y  F F  
Sbjct: 140 LLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYGNADGEYCKFPFLF 189

Query: 306 RVKKIDAAIYEKDTGKTHFFV 326
             K+ ++     DTG++  F+
Sbjct: 190 NGKEYNSC---TDTGRSDGFL 207



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 270 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 329
           E +   F  +++W+     L  GYP+ + +S   P  V+++DAA       KT+ F  ++
Sbjct: 479 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 537

Query: 330 YWRYDENMQSVDAGYPKIIDD 350
           +WRY+E  + +D G+PK+I D
Sbjct: 538 FWRYNEVKKKMDPGFPKLIAD 558



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 303 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 351
           +PE  +KIDA        K  FF  NEYW Y  +  +++ GYPK +  L
Sbjct: 463 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 509


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 52/141 (36%), Positives = 75/141 (53%), Gaps = 17/141 (12%)

Query: 189 YMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDG 248
           Y P+L  E VD A  +AF++WS+ + L F+R  + E DI+++F    +  D  PF G DG
Sbjct: 131 YTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRW-EHGDGYPFDGKDG 189

Query: 249 CLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---GYPRDVYSSFVFPE 305
            LAHAF PG G+GGD HFD+DE           W + E Q++    G     Y  F F  
Sbjct: 190 LLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYGNADGEYCKFPFLF 239

Query: 306 RVKKIDAAIYEKDTGKTHFFV 326
             K+ ++     DTG++  F+
Sbjct: 240 NGKEYNSC---TDTGRSDGFL 257



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 270 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 329
           E +   F  +++W+     L  GYP+ + +S   P  V+++DAA       KT+ F  ++
Sbjct: 529 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587

Query: 330 YWRYDENMQSVDAGYPKIIDD 350
           +WRY+E  + +D G+PK+I D
Sbjct: 588 FWRYNEVKKKMDPGFPKLIAD 608



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 303 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 351
           +PE  +KIDA        K  FF  NEYW Y  +  +++ GYPK +  L
Sbjct: 513 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 559


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 59/172 (34%), Positives = 79/172 (45%), Gaps = 48/172 (27%)

Query: 147 YLENCYYNLKSEINQIGRQ--RDSSPVLEKLKQMQNFFGLK-----DQN----------- 188
           YL+  Y N   E +QIG    R S+ ++ K+K++Q FFGL+     DQ            
Sbjct: 44  YLDKYYTN--KEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCG 101

Query: 189 ---------------------------YMPNLPQEDVDRATGKAFELWSNASALTFTRDF 221
                                      Y P++   +VD+A   A + WS+A  L+F R  
Sbjct: 102 VPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRIN 161

Query: 222 ESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273
             E DI++SF    D  D+ PF G  G LAHAF PG G+GGD HFDN E  T
Sbjct: 162 SGEADIMISFEN-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 263 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 322
           D  ++  E  T  F    H+ +     + G PR +Y  F FP  V++IDAA+Y ++  KT
Sbjct: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406

Query: 323 HFFVANEYWRYDENMQSVDAGYPK 346
            FFV +EY+ YDE  + ++  YPK
Sbjct: 407 LFFVGDEYYSYDERKRKMEKDYPK 430


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 46/108 (42%), Positives = 60/108 (55%), Gaps = 8/108 (7%)

Query: 164 RQRDSSPVLEKLKQMQNFFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFES 223
           R+    PV  K     ++   +  NY P++ +EDVD A  KAF++WSN + L F++    
Sbjct: 101 REMPGGPVWRK-----HYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTG 155

Query: 224 EGDIILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 270
             DI++  VF    H D   F G  G LAHAF PG GIGGD HFD DE
Sbjct: 156 MADILV--VFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           F+  K+W++   +    YP+ ++S F FP  VKKIDAA++     +T+FFV N+YWRYDE
Sbjct: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405

Query: 336 NMQSVDAGYPKII-DDLPGISKK 357
             Q +D GYPK+I  +  GI  K
Sbjct: 406 RRQMMDPGYPKLITKNFQGIGPK 428


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 10/118 (8%)

Query: 164 RQRDSSPVLEKLKQMQNFFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFT----- 218
           R+R+    L   K  Q        NY P + + D  +A  +AF++W   + LTF      
Sbjct: 150 RRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYH 209

Query: 219 --RDFESEGDIILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273
             +    E DI++ F   +  H D+SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 210 EIKSDRKEADIMIFFA--SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 265



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 32/92 (34%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query: 263 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 322
           D  ++  + R   F+  K+WV +E  +  GYP  +        R + ID A+  +  GKT
Sbjct: 430 DAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPR-EGIDTALRWEPVGKT 488

Query: 323 HFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 354
           +FF    YWRY E  ++ D GYPK I    GI
Sbjct: 489 YFFKGERYWRYSEERRATDPGYPKPITVWKGI 520



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 272 RTKDFRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 329
           +T  F+  ++W   E++  +  GYP+ +      P+  +    A   K+   T+F+   +
Sbjct: 487 KTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQ---GAFISKEGYYTYFYKGRD 543

Query: 330 YWRYDENMQSVDAGYPK-IIDDLPGISKK 357
           YW++D    SV+ GYP+ I+ D  G ++K
Sbjct: 544 YWKFDNQKLSVEPGYPRNILRDWMGCNQK 572


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 39/93 (41%), Positives = 55/93 (59%), Gaps = 6/93 (6%)

Query: 187 QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESE-----GDIILSFVFLADLH-DN 240
           +N  P +   +  +A  +AF++W N + LTF     SE      D+ ++ +F +  H D+
Sbjct: 137 KNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDS 196

Query: 241 SPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273
           SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 197 SPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 39/93 (41%), Positives = 55/93 (59%), Gaps = 6/93 (6%)

Query: 187 QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESE-----GDIILSFVFLADLH-DN 240
           +N  P +   +  +A  +AF++W N + LTF     SE      D+ ++ +F +  H D+
Sbjct: 137 KNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDS 196

Query: 241 SPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273
           SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 197 SPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 37/94 (39%), Positives = 56/94 (59%), Gaps = 5/94 (5%)

Query: 263 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYS--SFVFPERVKKIDAAIYEKDTG 320
           D  ++N +     F+ +K+WV ++  L  GYP D+ +  S + P     ID+AI+ +D G
Sbjct: 393 DAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHG---IDSAIWWEDVG 449

Query: 321 KTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 354
           KT+FF  + YWRY E M+++D GYPK I    GI
Sbjct: 450 KTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGI 483



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 242 PFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ--LLSGYPRDVYS 299
           P Y HD     +  P  GI   + ++ D  +T  F+  ++W   E+   +  GYP+ +  
Sbjct: 421 PGYPHDLITLGSGIPPHGIDSAIWWE-DVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITV 479

Query: 300 SFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPG 353
               PE  +    A   K+ G T+F+   EYW+++  +  V+ GYP+ I+ D  G
Sbjct: 480 WKGIPESPQ---GAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMG 531


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 14/130 (10%)

Query: 172 LEKLKQMQNFFGLKDQNYMPNLPQEDVDRATGKAFELWSNASALTFTR--------DFES 223
           ++ LK   N      QNY P + +     A  KAF +W +A+ L F            E 
Sbjct: 114 IQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEK 173

Query: 224 EGDIILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE---TRTKDFRSS 279
           + DI++ F      H D++PF G  G LAHA+ PGP IGGD HFD+ E    R +D   +
Sbjct: 174 QADIMIFFA--EGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGN 231

Query: 280 KHWVVQEDQL 289
             ++V   +L
Sbjct: 232 DIFLVAVHEL 241



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 1/79 (1%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           F+  KHWV  E  L  GYP+ +           KIDAA++    GKT+FF  N+Y+R++E
Sbjct: 382 FKGDKHWVFDEASLEPGYPKHI-KELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNE 440

Query: 336 NMQSVDAGYPKIIDDLPGI 354
            +++VD+ YPK I    GI
Sbjct: 441 ELRAVDSEYPKNIKVWEGI 459



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 11/79 (13%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAI---YEKDTGKTHFFVANEYWR 332
           F+    W V+ +Q++ GYP  +   +      + + A+I   YE+  GK  FF  +++W 
Sbjct: 336 FKERWFWRVRNNQVMDGYPMPIGQFW------RGLPASINTAYERKDGKFVFFKGDKHWV 389

Query: 333 YDENMQSVDAGYPKIIDDL 351
           +DE   S++ GYPK I +L
Sbjct: 390 FDE--ASLEPGYPKHIKEL 406


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 247
           +Y  +LP   VDR   KA  +W     L F +      DI++ F   A   D+ PF G  
Sbjct: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173

Query: 248 GCLAHAFPPGPGIGGDVHFDNDETRT 273
             LAHAF PG G+GGD HFD DE  T
Sbjct: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 39/96 (40%), Positives = 50/96 (52%), Gaps = 11/96 (11%)

Query: 187 QNYMPNLPQEDVDRATGKAFELWSNASALTFTR--------DFESEGDIILSFVFLADLH 238
           QNY   L       A  +AF +W  A+ L F            + E DI++  +F +  H
Sbjct: 149 QNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMV--LFASGFH 206

Query: 239 -DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273
            D+SPF G  G LAHA+ PGPG+GGD HFD DE  T
Sbjct: 207 GDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWT 242



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 3/98 (3%)

Query: 259 GIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYE 316
           G+ GD+   ++  + R   F+  ++W+ +E  L  GYP+ + +S+       +ID AI+ 
Sbjct: 414 GLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPL-TSYGLGIPYDRIDTAIWW 472

Query: 317 KDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 354
           + TG T FF  + YWR++E  Q  D GYPK I    GI
Sbjct: 473 EPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGI 510



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 276 FRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRY 333
           F+  ++W   E+      GYP+ +      P   K    A    D   T+F+   +YW++
Sbjct: 481 FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPK---GAFLSNDAAYTYFYKGTKYWKF 537

Query: 334 DENMQSVDAGYPKII 348
           D     ++ GYPK I
Sbjct: 538 DNERLRMEPGYPKSI 552


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 38/96 (39%), Positives = 49/96 (51%), Gaps = 11/96 (11%)

Query: 193 LPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAH 252
           L QE V +   +A ++WS+ + LTFT   E   DI++ F       D+ PF G  G LAH
Sbjct: 121 LVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFARYWH-GDDLPFDGPGGILAH 179

Query: 253 AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ 288
           AF P     GDVHFD DET          W + +DQ
Sbjct: 180 AFFPKTHREGDVHFDYDET----------WTIGDDQ 205



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 5/93 (5%)

Query: 263 DVHFDNDETRTKDFRSSKHWVVQ-EDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGK 321
           D  F++ +     F+ +++WV   E  +L   P        FP       A ++  +  K
Sbjct: 344 DAAFEDAQGHIWFFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHA----ALVWGPEKNK 399

Query: 322 THFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 354
            +FF   +YWR+  + + VD+  P+   D  G+
Sbjct: 400 IYFFRGRDYWRFHPSTRRVDSPVPRRATDWRGV 432


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 11/93 (11%)

Query: 261 GGDVHFDNDET---RTKD-----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDA 312
           G  +H D+ +    RT D     F+  ++WV +++ +  GYPR V S F  P     IDA
Sbjct: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLPPG--GIDA 433

Query: 313 AIYEKDTGKTHFFVANEYWRYDENMQSVDAGYP 345
           A       +T+FF    YWRYD++ + +D GYP
Sbjct: 434 AFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 34/76 (44%), Positives = 42/76 (55%), Gaps = 4/76 (5%)

Query: 205 AFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPG-PGIGGD 263
           A ++WS+ + L F     S  DI + F   AD +D  PF G  G +AHAF PG     GD
Sbjct: 163 ALKVWSDIAPLNFHEVAGSAADIQIDFS-KADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221

Query: 264 VHFDNDETRTKDFRSS 279
            HFD+DE  T  FRSS
Sbjct: 222 THFDDDEAWT--FRSS 235



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 253 AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQED--QLLSGYPRDVYSSFVFPERVKKI 310
           + PPG GI     + +++ RT  F+   +W   +    +  GYP     S ++      +
Sbjct: 425 SLPPG-GIDAAFSWAHND-RTYFFKDQLYWRYDDHTRHMDPGYPAQ---SPLWRGVPSTL 479

Query: 311 DAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 346
           D A+   D G ++FF   EYW+  +    V  GYP+
Sbjct: 480 DDAMRWSD-GASYFFRGQEYWKVLDGELEVAPGYPQ 514


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 7/86 (8%)

Query: 188 NYMPNLPQEDVDRATGKAFELWSNASALTF-TRDFESEGDIILSFVFLADLHD--NSPFY 244
           N+  +LP+  V  A   AF+LWSN SAL F         DI L+F F  D +D   + F 
Sbjct: 141 NWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTF-FQGDHNDGLGNAFD 199

Query: 245 GHDGCLAHAFPPGPGIGGDVHFDNDE 270
           G  G LAHAF P     G+ HFD DE
Sbjct: 200 GPGGALAHAFLPR---RGEAHFDQDE 222


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 1/83 (1%)

Query: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 247
           NY  ++    V  +   A  +WSN + L F +    + DI +SF   A   D  PF G  
Sbjct: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168

Query: 248 GCLAHAFPPGPGIGGDVHFDNDE 270
           G L HAF P  G  G VHFD +E
Sbjct: 169 GILGHAFLPNSGNPGVVHFDKNE 191


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 36/85 (42%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 193 LPQEDVDRATGKAFELWSNASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGC 249
           L QE V      A   W   S LTF      +G   DI++ F   A   D+ PF G  G 
Sbjct: 133 LSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFA-RAFHQDSYPFDGLGGT 191

Query: 250 LAHAFPPGP-GIGGDVHFDNDETRT 273
           LAHAF PG   I GD HFD++ET T
Sbjct: 192 LAHAFFPGEHPISGDTHFDDEETWT 216



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 335
           F   + WV Q+ QL  G  R +    + P   +++DA       GKT+     +YWRYDE
Sbjct: 385 FSGPQFWVFQDRQLEGG-ARPLTELGLPPG--EEVDAVFSWPQNGKTYLVRGRQYWRYDE 441

Query: 336 NMQSVDAGYPK 346
                D GYP+
Sbjct: 442 AAARPDPGYPR 452


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 247
           N    LP      A  +AF+ WSN + LTF        DI LSF      + ++ F G  
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174

Query: 248 GCLAHAFPPGPGIGGDVHFDNDETRTK 274
             LAHA  P     G VHFD DE  T+
Sbjct: 175 RVLAHADIPEL---GSVHFDEDEFWTE 198



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 8/77 (10%)

Query: 276 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVK-KIDAAIYEKDTGKTHFFVANEYWRYD 334
           F+  K W     ++  G+P+ +        RV+  +DAA+Y     K   F  + YW++D
Sbjct: 352 FKGDKVWRYINFKMSPGFPKKL-------NRVEPNLDAALYWPLNQKVFLFKGSGYWQWD 404

Query: 335 ENMQSVDAGYPKIIDDL 351
           E  ++  + YPK I  L
Sbjct: 405 ELARTDFSSYPKPIKGL 421



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 10/77 (12%)

Query: 276 FRSSKHWVVQEDQL----LSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYW 331
           F+ S +W  Q D+L     S YP+ +   F     V    +A      G+ +FF    YW
Sbjct: 395 FKGSGYW--QWDELARTDFSSYPKPIKGLFT---GVPNQPSAAMSWQDGRVYFFKGKVYW 449

Query: 332 RYDENMQSVDAGYPKII 348
           R ++ ++ V+ GYP+ I
Sbjct: 450 RLNQQLR-VEKGYPRNI 465



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 310 IDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 346
           +DAA+Y   T   HFF  ++ WRY     S   G+PK
Sbjct: 337 LDAAVYSPRTQWIHFFKGDKVWRYINFKMS--PGFPK 371


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score = 35.4 bits (80), Expect = 0.079
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 8/77 (10%)

Query: 197 DVDRATGKAFELWSNASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGCLAHA 253
           D  R    AF +WS  + L F  D  + G   DI L F     L     F G     AHA
Sbjct: 193 DQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHA 252

Query: 254 FPPGPGIGGDVHFDNDE 270
           +  G     D+HFD+DE
Sbjct: 253 WRLG-----DIHFDDDE 264



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 44/201 (21%), Positives = 81/201 (40%), Gaps = 34/201 (16%)

Query: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFE-------SEGDIILSF--------- 231
           NY+P  P  ++D +  KA +    +   +F   F+         G++++ F         
Sbjct: 304 NYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSW 363

Query: 232 VFLADLHDNSPFYGHDGCLAHAFP--PGPGIGGDVH---FDNDETRTKDFRSSKHW---- 282
            +L +  +N   YG    +   +P  P   I   VH   +  DE     F+ +++W    
Sbjct: 364 YWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYF--FQGNQYWRYDS 421

Query: 283 ----VVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQ 338
                + ED+    YP+ +   F  P     +D A Y++     +FF  +  + +D N  
Sbjct: 422 DKDQALTEDEQGKSYPKLISEGF--PGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRN 479

Query: 339 SVDAGYPKIIDDL-PGISKKN 358
            V   YPK I ++ P +  +N
Sbjct: 480 RVLNSYPKRITEVFPAVIPQN 500



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 250 LAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWV--VQEDQLLSGYPRDVYSSF--VFPE 305
           ++  FP  P       +D  +     F+ S  +   V  +++L+ YP+ +   F  V P+
Sbjct: 440 ISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQ 499

Query: 306 R--VKKIDAAIYEKDTGKTHFFVANEYWR 332
               + ID+A Y        FF  N YW+
Sbjct: 500 NHPFRNIDSAYYSYAYNSIFFFKGNAYWK 528


>gi|88853069 vitronectin precursor [Homo sapiens]
          Length = 478

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 12/79 (15%)

Query: 276 FRSSKHWVVQEDQLLSGYP---RDVYSSFVFPERVKKIDAAIYEKDT-GKTHFFVANEYW 331
           FR    + + E  +  GYP   RDV+           IDAA    +  GKT+ F  ++YW
Sbjct: 175 FRGQYCYELDEKAVRPGYPKLIRDVWGI------EGPIDAAFTRINCQGKTYLFKGSQYW 228

Query: 332 RYDENMQSVDAGYPKIIDD 350
           R+++ +  +D  YP+ I D
Sbjct: 229 RFEDGV--LDPDYPRNISD 245



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 3/69 (4%)

Query: 268 NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF-VFPERVKKIDAAIYEKDTG--KTHF 324
           N + +T  F+ S++W  ++  L   YPR++   F   P+ V    A      +G  + +F
Sbjct: 214 NCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYF 273

Query: 325 FVANEYWRY 333
           F   +YW Y
Sbjct: 274 FKGKQYWEY 282


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 15/29 (51%), Positives = 21/29 (72%), Gaps = 2/29 (6%)

Query: 320  GKTHFFVANEYWRYDENMQSVDAGYPKII 348
            GKT FF  ++YWR+  +++  DAGYPK I
Sbjct: 1072 GKTFFFKDSQYWRFTNDIK--DAGYPKPI 1098



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 268  NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF--VFPERVKKIDAAIYEKDTGKTHFF 325
            N E +T  F+ S++W    D   +GYP+ ++  F  +  + V  +  A Y+      +FF
Sbjct: 1069 NCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFF 1128


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,325,887
Number of Sequences: 37866
Number of extensions: 644592
Number of successful extensions: 1468
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1334
Number of HSP's gapped (non-prelim): 98
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.