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Search of human proteins with 154091028
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154091028 sorting nexin 29 [Homo sapiens]
(428 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154091028 sorting nexin 29 [Homo sapiens] 846 0.0
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 99 7e-21
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 55 1e-07
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 55 1e-07
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 55 1e-07
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 52 1e-06
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 50 3e-06
gi|66472382 nischarin [Homo sapiens] 50 5e-06
gi|17864088 sorting nexin 13 [Homo sapiens] 49 1e-05
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 48 2e-05
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 48 2e-05
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 47 3e-05
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 47 3e-05
gi|21735548 centrosomal protein 2 [Homo sapiens] 45 2e-04
gi|23111038 sorting nexin 2 [Homo sapiens] 45 2e-04
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 44 3e-04
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 44 3e-04
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 43 5e-04
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 43 5e-04
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 43 5e-04
gi|7662655 SBBI31 protein [Homo sapiens] 43 5e-04
gi|38708169 sorting nexin 25 [Homo sapiens] 43 6e-04
gi|33946313 ninein isoform 4 [Homo sapiens] 42 8e-04
gi|33946321 ninein isoform 5 [Homo sapiens] 42 8e-04
gi|148536871 ninein isoform 1 [Homo sapiens] 42 8e-04
gi|148536869 ninein isoform 2 [Homo sapiens] 42 8e-04
gi|221136814 coiled-coil domain containing 154 [Homo sapiens] 42 0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 0.001
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 42 0.001
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 42 0.001
>gi|154091028 sorting nexin 29 [Homo sapiens]
Length = 428
Score = 846 bits (2186), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASS 60
MHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASS
Sbjct: 1 MHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASS 60
Query: 61 PGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAAL 120
PGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAAL
Sbjct: 61 PGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAAL 120
Query: 121 RQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWS 180
RQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWS
Sbjct: 121 RQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWS 180
Query: 181 VDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQ 240
VDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQ
Sbjct: 181 VDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQ 240
Query: 241 ELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIK 300
ELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIK
Sbjct: 241 ELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIK 300
Query: 301 DDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSV 360
DDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSV
Sbjct: 301 DDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSV 360
Query: 361 MNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRN 420
MNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRN
Sbjct: 361 MNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRN 420
Query: 421 VEPQSGDL 428
VEPQSGDL
Sbjct: 421 VEPQSGDL 428
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 99.0 bits (245), Expect = 7e-21
Identities = 78/314 (24%), Positives = 138/314 (43%), Gaps = 42/314 (13%)
Query: 86 RQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQAL 145
R +T+ M E+EE+ + L +L G E S L+ ++ + + + +ER ++Q L
Sbjct: 1021 RHSTLGM-----EIEEQRQKLASLNSGSREQSG-LQASLEAEQEALEKDQERLEYEIQQL 1074
Query: 146 ARENEVLKVQLKKYVGAVQMLKREGQTAE--VPNLWSVDGEVTVAEQKPGEIAEELAS-- 201
++ + K + G + EG+ A +P V + + + EE
Sbjct: 1075 KQKIYEVDGVQKDHHGTL-----EGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRR 1129
Query: 202 --SYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSED 259
R + E + ++ NE+LH + ++ +M + G P DL
Sbjct: 1130 LQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSL---GANPDDLKDP--- 1183
Query: 260 QSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHK 319
I + IP L G+ +A ++V I + D+ W ++RRY+ FR +H
Sbjct: 1184 -------------IKISIPRYVLCGQGKDAHFEFEVKITVLDETWTVFRRYSRFREMHKT 1230
Query: 320 LQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVMNKVIQM------VPEFAA 373
L+ KY ++ A FPPKK GNKD + + ERR L+ YLR + ++Q + +
Sbjct: 1231 LKLKYAELAALEFPPKKLFGNKDERVIAERRSHLEKYLRDFFSVMLQSATSPLHINKVGL 1290
Query: 374 SPKKETLIQLMPFF 387
+ K T+ + PFF
Sbjct: 1291 TLSKHTICEFSPFF 1304
Score = 30.0 bits (66), Expect = 4.2
Identities = 36/199 (18%), Positives = 87/199 (43%), Gaps = 24/199 (12%)
Query: 67 LSSLLPSASVPESMTISELRQATVAMMNRKDE----LEEENRSLRNLLDGEMEHSAALRQ 122
L LL E + E ++ + +++E ++EE + L+ L + E + Q
Sbjct: 669 LKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQ 728
Query: 123 EVDTLKRKVAEQEERQGMKVQALARENEV-------LKVQLKKYVGAVQMLKR------E 169
E+D L+++ EQ + ++ + L + + L+ QL++ +Q+L+R E
Sbjct: 729 ELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVE 788
Query: 170 GQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSY-------ERKLIEVAEMHGELIEFNE 222
+ ++ + V A E EEL + R+L+++ + +L++ +
Sbjct: 789 EEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKD 848
Query: 223 RLHRALVAKEALVSQMRQE 241
L + + ++ ++ ++ E
Sbjct: 849 ILKKEVQEEQEILECLKCE 867
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 274 NVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFP 333
+V IPS + F VY+V + + EW ++RRY EF L++ L+ ++P + A P
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAM-ALKIP 73
Query: 334 PKKAIG-NKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQL 383
K+ G N D F+++RR L ++++++ PE P +Q+
Sbjct: 74 AKRIFGDNFDPDFIKQRRAGLNEFIQNLVR-----YPELYNHPDVRAFLQM 119
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 274 NVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFP 333
+V IPS + F VY+V + + EW ++RRY EF L++ L+ ++P + A P
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAM-ALKIP 73
Query: 334 PKKAIG-NKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQL 383
K+ G N D F+++RR L ++++++ PE P +Q+
Sbjct: 74 AKRIFGDNFDPDFIKQRRAGLNEFIQNLVR-----YPELYNHPDVRAFLQM 119
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 55.1 bits (131), Expect = 1e-07
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 274 NVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFP 333
+V IPS + F VY+V + + EW ++RRY EF L++ L+ ++P + A P
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAM-ALKIP 73
Query: 334 PKKAIG-NKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQL 383
K+ G N D F+++RR L ++++++ PE P +Q+
Sbjct: 74 AKRIFGDNFDPDFIKQRRAGLNEFIQNLVR-----YPELYNHPDVRAFLQM 119
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 3/60 (5%)
Query: 301 DDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSV 360
++ W I RRY++F L++ LQ + PPKK IGN D +F+ ER+K LQNYL +
Sbjct: 47 ENSWQIVRRYSDFDLLNNSLQIAGLSLP---LPPKKLIGNMDREFIAERQKGLQNYLNVI 103
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 50.4 bits (119), Expect = 3e-06
Identities = 46/193 (23%), Positives = 89/193 (46%), Gaps = 20/193 (10%)
Query: 51 GLRYSVEASSPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLL 110
G + S E S+ G G + + P +S P + E + M ++L EEN +L+N +
Sbjct: 317 GPQQSAEGSASGGG--MQAAAPPSSQPHPQQLQEQEE----MQEEMEKLREENETLKNEI 370
Query: 111 DGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQ-ALARENEVLKVQLKKYVGAVQMLKRE 169
D LR E+D ++ E++ Q +++ L R N+ ++ + A + R
Sbjct: 371 D-------ELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRY 423
Query: 170 GQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALV 229
QT E +DGE+ + ++ ++A++++ +L V E + NE+L + L+
Sbjct: 424 AQTGE------IDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLI 477
Query: 230 AKEALVSQMRQEL 242
E ++ EL
Sbjct: 478 EVEIAKQALQNEL 490
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 49.7 bits (117), Expect = 5e-06
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 288 NAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVE 347
+ + VY + + EW + RY++F LH KL + ++ PPKK IG VE
Sbjct: 28 DTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAER-KIDKNLLPPKKIIGKNSRSLVE 86
Query: 348 ERRKQLQNYLRSVMNKVIQMVPEFAA 373
+R K L+ YL+ ++ + P A
Sbjct: 87 KREKDLEVYLQKLLAAFPGVTPRVLA 112
>gi|17864088 sorting nexin 13 [Homo sapiens]
Length = 957
Score = 48.5 bits (114), Expect = 1e-05
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
Query: 252 DLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIK----DDEWNIY 307
DLS S D S+ ++ +I + + +Y + + + ++ W Y
Sbjct: 549 DLSNVSSDDSVQ---------LHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTY 599
Query: 308 RRYTEFRSLHHKLQNKYPQVRA-YNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361
RRY++F H ++ ++ + + P KK N D F+E+R+K L YL+ ++
Sbjct: 600 RRYSDFHDFHMRITEQFESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLL 654
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/74 (35%), Positives = 47/74 (63%), Gaps = 3/74 (4%)
Query: 290 FHVYQVYIRIKDDE-WNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAI-GNKDAKFVE 347
F VY++ ++ +E W ++RRYT+F L+ KL+ +P R PPK+ N +A F+E
Sbjct: 124 FTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFR-LALPPKRWFKDNYNADFLE 182
Query: 348 ERRKQLQNYLRSVM 361
+R+ LQ +L++++
Sbjct: 183 DRQLGLQAFLQNLV 196
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/74 (35%), Positives = 47/74 (63%), Gaps = 3/74 (4%)
Query: 290 FHVYQVYIRIKDDE-WNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAI-GNKDAKFVE 347
F VY++ ++ +E W ++RRYT+F L+ KL+ +P R PPK+ N +A F+E
Sbjct: 124 FTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFR-LALPPKRWFKDNYNADFLE 182
Query: 348 ERRKQLQNYLRSVM 361
+R+ LQ +L++++
Sbjct: 183 DRQLGLQAFLQNLV 196
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 47.0 bits (110), Expect = 3e-05
Identities = 20/60 (33%), Positives = 35/60 (58%)
Query: 302 DEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361
+ W++YRRY EF L KL + P K+ IG K+ +F++ +R++ Q YL+ ++
Sbjct: 556 EHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLL 615
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 47.0 bits (110), Expect = 3e-05
Identities = 20/60 (33%), Positives = 35/60 (58%)
Query: 302 DEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361
+ W++YRRY EF L KL + P K+ IG K+ +F++ +R++ Q YL+ ++
Sbjct: 609 EHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLL 668
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/191 (24%), Positives = 87/191 (45%), Gaps = 22/191 (11%)
Query: 96 KDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQ 155
KD+LE++ + L + + QE+ L++++ E E+ +K Q+L + + +
Sbjct: 1752 KDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRA 1811
Query: 156 LKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHG 215
L + ++ L++E Q A+ G+ E++ E A+ L + E+ + + E HG
Sbjct: 1812 LAQRDQELEALQQEQQQAQ--------GQ----EERVKEKADALQGALEQAHMTLKERHG 1859
Query: 216 ELIEFNE---RLHRALVAKEALVSQMRQELIDLRGPVPGD------LSQTSEDQSLSDFE 266
EL + E RL L + V + + L DLR L Q +Q+ + E
Sbjct: 1860 ELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQA-QEHE 1918
Query: 267 ISNRALINVWI 277
+ RAL + W+
Sbjct: 1919 VETRALQDSWL 1929
Score = 35.8 bits (81), Expect = 0.077
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 29/170 (17%)
Query: 71 LPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRK 130
L +A+V S L V + + +LEEEN+S+ + ++ A Q + L+
Sbjct: 594 LRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME-------AAEQARNALQVD 646
Query: 131 VAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQ 190
+AE E+R+ +AL +N L+ QL+K E AE+ ++ ++
Sbjct: 647 LAEAEKRR----EALWEKNTHLEAQLQK---------AEEAGAEL------QADLRDIQE 687
Query: 191 KPGEIAEELASS---YERKLIEVAEMHGELIEFNERLHRALVAKEALVSQ 237
+ EI ++L+ S E ++ ++H E E L RA+ KEALV +
Sbjct: 688 EKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVRE 737
Score = 35.4 bits (80), Expect = 0.100
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 34/185 (18%)
Query: 69 SLLPSASVPESMTISELRQ-------ATVAMMNRKDELEEENRSLRNLLDGEMEHSAALR 121
+L+ S + +LRQ A + + D+ EEE ++LR L L
Sbjct: 389 TLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQ-------KLT 441
Query: 122 QEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSV 181
E DTL + + QG +V +L++E E+L+ ++ +++L++E W +
Sbjct: 442 GERDTL---AGQTVDLQG-EVDSLSKERELLQKAREELRQQLEVLEQEA--------WRL 489
Query: 182 DGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQE 241
V V Q G+ A+ +K + E+H + E ERL L+ EA S+ E
Sbjct: 490 R-RVNVELQLQGDSAQG------QKEEQQEELHLAVRE-RERLQEMLMGLEAKQSESLSE 541
Query: 242 LIDLR 246
LI LR
Sbjct: 542 LITLR 546
Score = 33.5 bits (75), Expect = 0.38
Identities = 40/206 (19%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 78 ESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEER 137
+S I +L + + E ++E +S R ++ L Q+++ +++ Q+ER
Sbjct: 1607 QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKER 1666
Query: 138 QGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIA- 196
+ R+ ++L+ L++ +++ RE T + ++ + G +
Sbjct: 1667 IQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEH 1726
Query: 197 --------EELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGP 248
E+ + + E+ E+ +L + + LHR + L+SQ QE++ L+
Sbjct: 1727 MKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQ 1786
Query: 249 VPGDLSQTS-EDQSL-SDFEISNRAL 272
+ Q ++QSL S + + RAL
Sbjct: 1787 LQEAREQGELKEQSLQSQLDEAQRAL 1812
Score = 32.7 bits (73), Expect = 0.65
Identities = 44/183 (24%), Positives = 87/183 (47%), Gaps = 28/183 (15%)
Query: 84 ELRQATVAMMNRKDELEEENRSLRNLLD-GEM---------EHSAALRQ-------EVDT 126
+LR A A+ + +E+E E + L + GE+ E+ A L Q EV+T
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVET 1439
Query: 127 LKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVT 186
L+ ++ E E+++ M+ AL E+L + LKK V + ++ Q E+ SV +
Sbjct: 1440 LRGQIQELEKQREMQKAAL----ELLSLDLKKRNQEVDL--QQEQIQELEKCRSVLEHLP 1493
Query: 187 VA----EQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQEL 242
+A EQK E++ + + + + +L+E E+ + + ++ V ++++L
Sbjct: 1494 MAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLEL-EKKDQMIESQRGQVQDLKKQL 1552
Query: 243 IDL 245
+ L
Sbjct: 1553 VTL 1555
Score = 28.9 bits (63), Expect = 9.4
Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 85 LRQATVAMMNRKDELEEENRSLRNL-----LDGEMEHSAALRQEVDTLKRKVAEQEERQG 139
L++A + + + LE+E LR + L G+ Q+ + L V E+E Q
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQ-EELHLAVRERERLQE 526
Query: 140 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEEL 199
M + A+++E L +L A++ EG+ L EVT A + + EL
Sbjct: 527 MLMGLEAKQSESLS-ELITLREALESSHLEGEL-----LRQEQTEVTAALARAEQSIAEL 580
Query: 200 ASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQ 240
+SS EVA++ ++ + + K L Q+ Q
Sbjct: 581 SSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQ 621
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 20/106 (18%)
Query: 284 GKAANAFHVYQVYIR-----IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPP---- 334
G NA+ Y+V + E+++ RR+++F LH KL +KY V Y PP
Sbjct: 153 GDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV-GYIVPPAPEK 211
Query: 335 ------KKAIGNKDA---KFVEERRKQLQNYL-RSVMNKVIQMVPE 370
K +G +D+ +FVE+RR L+ YL R+V + + P+
Sbjct: 212 SIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPD 257
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 43.9 bits (102), Expect = 3e-04
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 36/238 (15%)
Query: 96 KDELEEENRSLRNLLD---GE-MEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEV 151
+ ELE N+SL L D GE +EH+AALR D + + A+ +E +V+ L EN
Sbjct: 229 QQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQE----QVEGLLAENNA 284
Query: 152 LKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVA 211
L+ L A++ + QTA+ L + EQ G LA+ +++ E
Sbjct: 285 LRTSL----AALEQI----QTAKTQEL------NMLREQTTG-----LAAELQQQQAEYE 325
Query: 212 EMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRA 271
++ G+ + N +L +L A L+ Q+ QE+ + + +L + + + A
Sbjct: 326 DLMGQKDDLNSQLQESLRANSRLLEQL-QEIGQEKEQLTQELQEARKSAEKRKAMLDELA 384
Query: 272 LINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRY-TEFRSLHHKLQNKYPQVR 328
+ L+ K+ + + V +R + + + RY E R LH + + ++R
Sbjct: 385 MET-------LQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELR 435
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 43.9 bits (102), Expect = 3e-04
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 36/238 (15%)
Query: 96 KDELEEENRSLRNLLD---GE-MEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEV 151
+ ELE N+SL L D GE +EH+AALR D + + A+ +E +V+ L EN
Sbjct: 282 QQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQE----QVEGLLAENNA 337
Query: 152 LKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVA 211
L+ L A++ + QTA+ L + EQ G LA+ +++ E
Sbjct: 338 LRTSL----AALEQI----QTAKTQEL------NMLREQTTG-----LAAELQQQQAEYE 378
Query: 212 EMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRA 271
++ G+ + N +L +L A L+ Q+ QE+ + + +L + + + A
Sbjct: 379 DLMGQKDDLNSQLQESLRANSRLLEQL-QEIGQEKEQLTQELQEARKSAEKRKAMLDELA 437
Query: 272 LINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRY-TEFRSLHHKLQNKYPQVR 328
+ L+ K+ + + V +R + + + RY E R LH + + ++R
Sbjct: 438 MET-------LQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELR 488
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/152 (25%), Positives = 69/152 (45%), Gaps = 26/152 (17%)
Query: 229 VAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAAN 288
V + L+S QE + P P + E++ F+++ V I G N
Sbjct: 108 VLAKTLISLPPQEATNSSKPQP-TYEELEEEEQEDQFDLT------VGITDPEKIGDGMN 160
Query: 289 AFHVYQVYIR-----IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPP--------- 334
A+ Y+V + + ++ + RR+++F L+ KL K+ Q + PP
Sbjct: 161 AYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQ-NGFIVPPPPEKSLIGM 219
Query: 335 -KKAIGNKD---AKFVEERRKQLQNYLRSVMN 362
K +G +D A+F+E+RR L+ YL+ ++N
Sbjct: 220 TKVKVGKEDSSSAEFLEKRRAALERYLQRIVN 251
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/152 (25%), Positives = 69/152 (45%), Gaps = 26/152 (17%)
Query: 229 VAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAAN 288
V + L+S QE + P P + E++ F+++ V I G N
Sbjct: 108 VLAKTLISLPPQEATNSSKPQP-TYEELEEEEQEDQFDLT------VGITDPEKIGDGMN 160
Query: 289 AFHVYQVYIR-----IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPP--------- 334
A+ Y+V + + ++ + RR+++F L+ KL K+ Q + PP
Sbjct: 161 AYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQ-NGFIVPPPPEKSLIGM 219
Query: 335 -KKAIGNKD---AKFVEERRKQLQNYLRSVMN 362
K +G +D A+F+E+RR L+ YL+ ++N
Sbjct: 220 TKVKVGKEDSSSAEFLEKRRAALERYLQRIVN 251
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Query: 279 SVFLRGKAANAFHVYQVYIRI----KDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPP 334
SVF K N Y +RI + + ++R + EF+ LH+KL +P + FP
Sbjct: 1428 SVFTYHKKYNPDKHYIYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPN 1487
Query: 335 KKAIGNKDAKFVEERRK-QLQNYLRSVMN 362
+ +G K V +RK +L +YL+S+MN
Sbjct: 1488 RMVLGRTHIKDVAAKRKIELNSYLQSLMN 1516
>gi|7662655 SBBI31 protein [Homo sapiens]
Length = 169
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/92 (28%), Positives = 51/92 (55%), Gaps = 9/92 (9%)
Query: 273 INVWIPSV-FLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQN--KYPQVRA 329
+ V+IPS + + V+++ + + + + +RY+EF +LH KL+ K P++
Sbjct: 1 MEVYIPSFRYEESDLERGYTVFKIEVLMNGRKHFVEKRYSEFHALHKKLKKCIKTPEI-- 58
Query: 330 YNFPPKKAIGNKDAKFVEERRKQLQNYLRSVM 361
P K + N K +E+RR+ L+ YL++V+
Sbjct: 59 ----PSKHVRNWVPKVLEQRRQGLETYLQAVI 86
>gi|38708169 sorting nexin 25 [Homo sapiens]
Length = 840
Score = 42.7 bits (99), Expect = 6e-04
Identities = 19/66 (28%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Query: 299 IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNK--DAKFVEERRKQLQNY 356
++ W + RR +EF++LH KL P ++ P + K D KF+E+ + QL +
Sbjct: 542 VETKNWTVPRRLSEFQNLHRKLSECVPSLKKVQLPSLSKLPFKSIDQKFMEKSKNQLNKF 601
Query: 357 LRSVMN 362
L+++++
Sbjct: 602 LQNLLS 607
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
Query: 80 MTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQG 139
+T SE++Q + ++L++EN LRN + E + ++ TL +E
Sbjct: 1506 ITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLN----GSQEEMW 1561
Query: 140 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEEL 199
K + + +EN ++ ++ + LK + Q ++ N + + + ++K E+ + L
Sbjct: 1562 QKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENT-ELSQKNSQNQEKLQELNQRL 1620
Query: 200 ASSYERKLIE-----VAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLR 246
+K E + E E E L R V LVS + EL +++
Sbjct: 1621 TEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVK 1672
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 113 EMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQT 172
E H A R E + + +V +EE+ ++ + + LK +L + + + +REG
Sbjct: 694 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFER-EREGLQ 752
Query: 173 AEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNER 223
+ W+ + + ++ E+L S E+ +E E+ EL+E ++R
Sbjct: 753 SSA---WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQR 800
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
Query: 80 MTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQG 139
+T SE++Q + ++L++EN LRN + E + ++ TL +E
Sbjct: 1500 ITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLN----GSQEEMW 1555
Query: 140 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEEL 199
K + + +EN ++ ++ + LK + Q ++ N + + + ++K E+ + L
Sbjct: 1556 QKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENT-ELSQKNSQNQEKLQELNQRL 1614
Query: 200 ASSYERKLIE-----VAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLR 246
+K E + E E E L R V LVS + EL +++
Sbjct: 1615 TEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVK 1666
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 113 EMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQT 172
E H A R E + + +V +EE+ ++ + + LK +L + + + +REG
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFER-EREGLQ 746
Query: 173 AEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNER 223
+ W+ + + ++ E+L S E+ +E E+ EL+E ++R
Sbjct: 747 SSA---WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQR 794
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
Query: 80 MTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQG 139
+T SE++Q + ++L++EN LRN + E + ++ TL +E
Sbjct: 1500 ITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLN----GSQEEMW 1555
Query: 140 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEEL 199
K + + +EN ++ ++ + LK + Q ++ N + + + ++K E+ + L
Sbjct: 1556 QKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENT-ELSQKNSQNQEKLQELNQRL 1614
Query: 200 ASSYERKLIE-----VAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLR 246
+K E + E E E L R V LVS + EL +++
Sbjct: 1615 TEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVK 1666
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 113 EMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQT 172
E H A R E + + +V +EE+ ++ + + LK +L + + + +REG
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFER-EREGLQ 746
Query: 173 AEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNER 223
+ W+ + + ++ E+L S E+ +E E+ EL+E ++R
Sbjct: 747 SSA---WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQR 794
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
Query: 80 MTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQG 139
+T SE++Q + ++L++EN LRN + E + ++ TL +E
Sbjct: 1500 ITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLN----GSQEEMW 1555
Query: 140 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEEL 199
K + + +EN ++ ++ + LK + Q ++ N + + + ++K E+ + L
Sbjct: 1556 QKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENT-ELSQKNSQNQEKLQELNQRL 1614
Query: 200 ASSYERKLIE-----VAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLR 246
+K E + E E E L R V LVS + EL +++
Sbjct: 1615 TEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVK 1666
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 113 EMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQT 172
E H A R E + + +V +EE+ ++ + + LK +L + + + +REG
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFER-EREGLQ 746
Query: 173 AEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNER 223
+ W+ + + ++ E+L S E+ +E E+ EL+E ++R
Sbjct: 747 SSA---WTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQR 794
>gi|221136814 coiled-coil domain containing 154 [Homo sapiens]
Length = 667
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 14/189 (7%)
Query: 85 LRQATVAMMNRKDELEEENRSLRNLLDGEMEHS-AALRQEVDTLKRKVAEQEERQGMKVQ 143
L+++ +A+ R E L L GE+E LR ++ R + Q E + Q
Sbjct: 250 LQKSFLALEKRMKASESSRLKLEGSLRGELESRWEKLRGLMEERLRALQGQHEESHLLEQ 309
Query: 144 ALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSY 203
+ V QL K+V Q AE W G + E + GE+A + +
Sbjct: 310 CQGLDAAV--AQLTKFVQQNQASLNRVLLAE-EKAWDAKGRLE--ESRAGELAAYVQENL 364
Query: 204 ERKLI--EVA--EMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSED 259
E + E+A EMHGEL+ E+ RAL EA V+Q+ +L +L G +P S+
Sbjct: 365 EAAQLAGELARQEMHGELVLLREK-SRAL---EASVAQLAGQLKELSGHLPALSSRLDLQ 420
Query: 260 QSLSDFEIS 268
+ + +S
Sbjct: 421 EQMLGLRLS 429
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.0 bits (97), Expect = 0.001
Identities = 74/335 (22%), Positives = 145/335 (43%), Gaps = 37/335 (11%)
Query: 95 RKDELEEENRSLRNLLDGEMEHSAALR-------QEVDTLKRKVAEQEERQGMKVQALAR 147
+K +L EE +L+ L+ ++ +AA + QEV+ LK+ + E+ + ++Q + +
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 148 EN----EVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSY 203
++ E L QL++ L++ QT E + EV V Q G+ S +
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLE-NERGELANEVKVLLQGKGD------SEH 1245
Query: 204 ERKLIEVAEMHGELIEFN--ERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQS 261
+RK +E A++ ++FN ER+ L K V++++ EL + V G LSQ+ S
Sbjct: 1246 KRKKVE-AQLQELQVKFNEGERVRTELADK---VTKLQVELDN----VTGLLSQSDSKSS 1297
Query: 262 --LSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHK 319
DF L + L+ + + +++D++ + + E H
Sbjct: 1298 KLTKDFSALESQLQDT---QELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 320 LQNKYPQVRAYNFPPKKAIGNKDA--KFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKK 377
L+ + + A KK + + + EE +++LQ L + + + V + K
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 378 ETLIQ--LMPFFVDITPPGEPVNSRPKAASRFPKL 410
+T +Q L VD+ + + K +F +L
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
Score = 37.0 bits (84), Expect = 0.034
Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 18/185 (9%)
Query: 78 ESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEER 137
E+ +E + + +K ELEE L ++ E E L+ E +++ + E EE+
Sbjct: 892 ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQ 951
Query: 138 QGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQKPGEIAE 197
++ + AR+ K+QL+K ++ K E + + D +A++K ++ E
Sbjct: 952 --LEEEESARQ----KLQLEKVTTEAKLKKLEEE-----QIILEDQNCKLAKEK--KLLE 998
Query: 198 ELASSYERKLIEVAEMHGELIEFNERLHRALVA--KEAL--VSQMRQELIDLRGPVPGDL 253
+ + + L E E L + + H A++ +E L + RQEL R + GD
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNK-HEAMITDLEERLRREEKQRQELEKTRRKLEGDS 1057
Query: 254 SQTSE 258
+ S+
Sbjct: 1058 TDLSD 1062
Score = 34.3 bits (77), Expect = 0.22
Identities = 34/147 (23%), Positives = 73/147 (49%), Gaps = 8/147 (5%)
Query: 67 LSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDT 126
L+ + ++S ++ + E R+ + ++ELEEE + L++ ++ + +++T
Sbjct: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE-LINDRLKKANLQIDQINT 1764
Query: 127 ---LKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDG 183
L+R A++ E Q L R+N+ LKV+L++ G V+ + TA + ++
Sbjct: 1765 DLNLERSHAQKNENAR---QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 184 EVTVAEQKPGEIAEELASSYERKLIEV 210
++ E K + A + E+KL +V
Sbjct: 1822 QLD-NETKERQAACKQVRRTEKKLKDV 1847
Score = 29.6 bits (65), Expect = 5.5
Identities = 36/173 (20%), Positives = 75/173 (43%), Gaps = 21/173 (12%)
Query: 82 ISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMK 141
I++L + ++ ELE+ R L + A L+ ++ LK ++A++EE
Sbjct: 1029 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 1088
Query: 142 VQALARENEVLKVQLKKYVGAVQMLKREGQTAEV-PNLWSVDGEVTVAEQKPGEIAEEL- 199
+ + E + LKK + + E Q +E+ +L S AE++ ++ EEL
Sbjct: 1089 LARVEEEAAQKNMALKK------IRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 200 -----------ASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQE 241
+++ +++L E +++ + L EA + +MRQ+
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILK--KTLEEEAKTHEAQIQEMRQK 1193
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 19/103 (18%)
Query: 278 PSVFLRGKAANAFHVYQVYIR-----IKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNF 332
P G NA+ Y+V + + ++ + RR+++F L+ KL K+ Q +
Sbjct: 85 PQDLFAGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQ-NGFIV 143
Query: 333 PP----------KKAIGNKD---AKFVEERRKQLQNYLRSVMN 362
PP K +G +D A+F+E+RR L+ YL+ ++N
Sbjct: 144 PPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVN 186
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/173 (24%), Positives = 84/173 (48%), Gaps = 23/173 (13%)
Query: 113 EMEHSAALRQ---EVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKRE 169
E+EHS +++Q +V +L+ KV Q + Q + ++L +++ +V++++ +GA +
Sbjct: 441 ELEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSL--QDKAAEVEVER-MGAKGLQLEL 497
Query: 170 GQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSY---ERKLIEVAEMHGELIEFNERLH- 225
+ E W + AE++ + ++SS E + +V +L N RL
Sbjct: 498 SRAQEARRRWQQ--QTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSY 555
Query: 226 --------RALVAKEALVSQMRQELIDLRGPVPG---DLSQTSEDQSLSDFEI 267
R L+A++ ++Q+RQE L PV +L Q E+++ D E+
Sbjct: 556 AVRKVHTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAEL 608
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 76 VPESMTISELRQATVAMMNRKDELEEENRSLR---NLLDGEMEHSAALRQEVDTLKRKVA 132
+ + +++LRQ + + ++ E + LR N LD E++ SA L Q+ R+
Sbjct: 567 IARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQG 626
Query: 133 EQEERQGMKV-QALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQK 191
E E +Q KV Q L +E + + L +G + R+GQ S+ E+T ++
Sbjct: 627 EAERQQLSKVAQQLEQELQQTQESLAS-LGLQLEVARQGQQESTEEAASLRQELTQQQEL 685
Query: 192 PGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQ 240
G+ +E + E +L E +L + RL+ A V +RQ
Sbjct: 686 YGQALQEKVAEVETRLRE------QLSDTERRLNEARREHAKAVVSLRQ 728
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,806,573
Number of Sequences: 37866
Number of extensions: 803120
Number of successful extensions: 3936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 3185
Number of HSP's gapped (non-prelim): 1030
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.