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Search of human proteins with 153946397
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
(1029 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 2038 0.0
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 1632 0.0
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 1606 0.0
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 1606 0.0
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 1599 0.0
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 1589 0.0
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 1249 0.0
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 1246 0.0
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 378 e-104
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 378 e-104
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 378 e-104
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 378 e-104
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 378 e-104
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 378 e-104
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 378 e-104
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 372 e-103
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 372 e-103
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 365 e-101
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 363 e-100
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 363 e-100
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 363 e-100
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 363 e-100
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 363 e-100
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 345 1e-94
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 343 4e-94
gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens] 342 1e-93
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 262 1e-69
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 230 5e-60
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 230 5e-60
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 229 1e-59
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
Length = 1029
Score = 2038 bits (5279), Expect = 0.0
Identities = 1029/1029 (100%), Positives = 1029/1029 (100%)
Query: 1 MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELS 60
MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELS
Sbjct: 1 MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELS 60
Query: 61 TKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCF 120
TKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCF
Sbjct: 61 TKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCF 120
Query: 121 VAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVI 180
VAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVI
Sbjct: 121 VAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVI 180
Query: 181 RGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFT 240
RGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFT
Sbjct: 181 RGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFT 240
Query: 241 HENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFI 300
HENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFI
Sbjct: 241 HENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFI 300
Query: 301 HLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMA 360
HLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMA
Sbjct: 301 HLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMA 360
Query: 361 RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFT 420
RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFT
Sbjct: 361 RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFT 420
Query: 421 KSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMRE 480
KSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMRE
Sbjct: 421 KSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMRE 480
Query: 481 KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE 540
KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE
Sbjct: 481 KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE 540
Query: 541 MKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDP 600
MKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDP
Sbjct: 541 MKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDP 600
Query: 601 PRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISK 660
PRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISK
Sbjct: 601 PRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISK 660
Query: 661 VDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAV 720
VDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAV
Sbjct: 661 VDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAV 720
Query: 721 TGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 780
TGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK
Sbjct: 721 TGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 780
Query: 781 SIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKR 840
SIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKR
Sbjct: 781 SIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKR 840
Query: 841 LPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKY 900
LPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKY
Sbjct: 841 LPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKY 900
Query: 901 LNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVL 960
LNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVL
Sbjct: 901 LNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVL 960
Query: 961 IFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPD 1020
IFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPD
Sbjct: 961 IFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPD 1020
Query: 1021 GWVERETYY 1029
GWVERETYY
Sbjct: 1021 GWVERETYY 1029
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 1632 bits (4225), Expect = 0.0
Identities = 804/999 (80%), Positives = 902/999 (90%), Gaps = 1/999 (0%)
Query: 32 KREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPP 91
K++++++ ++ELKKEV MDDHKL+L+EL KY VDL+KG ++QRA+++L R GPN +TPP
Sbjct: 22 KKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPP 81
Query: 92 PTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVT 151
PTTPEWVKFC+QLFGGFS+LLW GAILCF+AY IQ +EP+ DNLYL +VL+ VVIVT
Sbjct: 82 PTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVT 141
Query: 152 GCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADL 211
GCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKMQIN +EVV+GDLVE+KGGDRVPADL
Sbjct: 142 GCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADL 201
Query: 212 RLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGD 271
R+IS+ GCKVDNSSLTGESEPQ+RSP+FTHENPLETRNICFFSTNCVEGTARGIVIATGD
Sbjct: 202 RIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGD 261
Query: 272 STVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIF 331
TVMGRIA+L SGL VG+TPIA EIEHFI LIT VAVFLGV+FF LSL+LGY WLEA+IF
Sbjct: 262 RTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIF 321
Query: 332 LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ
Sbjct: 322 LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 381
Query: 392 NRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIA 451
NRMTVAHMWFD ++EADTTE+Q+G TF K S TW L+RIAGLCNRA FKA QE + ++
Sbjct: 382 NRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVS 441
Query: 452 KRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHV 511
KR T GDASESALLK IE S SV +MR++NPKVAEIPFNSTNKYQ+SIH REDS Q+HV
Sbjct: 442 KRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHV 501
Query: 512 LMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-S 570
L+MKGAPERIL+ CST L+ G+E ++ EM++AFQNAY+ELGGLGERVLGFC LNLPS
Sbjct: 502 LVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGK 561
Query: 571 FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITA 630
F +GF F+TDE+NFP + LCFVGL+SMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITA
Sbjct: 562 FPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 621
Query: 631 KAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQN 690
KAIAKGVGIISEG ET E++AARL IP+S+V+ AKA VVHG++LKD+ S+QLD+IL+N
Sbjct: 622 KAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKN 681
Query: 691 HPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 750
H EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ
Sbjct: 682 HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 741
Query: 751 AADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGT 810
AADMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII IPLPLGT
Sbjct: 742 AADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGT 801
Query: 811 ITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALA 870
+TILCIDLGTDMVPAISLAYE+AESDIMKR PRN +TD LVN RLI MAYGQIGMIQAL
Sbjct: 802 VTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALG 861
Query: 871 GFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFV 930
GFFTYFVILAENGF P LLGIRL W+D+ +NDLEDSYGQ+WTYEQRKVVEFTC TAFF
Sbjct: 862 GFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFA 921
Query: 931 TIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLK 990
+IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+LEET LAAFLSY PGM VALRMYPLK
Sbjct: 922 SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLK 981
Query: 991 ITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
+TWW CA PYS+LIF+YDE+RKL++R++P GWVE+ETYY
Sbjct: 982 VTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
Length = 1023
Score = 1606 bits (4158), Expect = 0.0
Identities = 797/1003 (79%), Positives = 890/1003 (88%), Gaps = 2/1003 (0%)
Query: 29 KMVKREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTV 88
K K+ K+ R+M+ELKKEV MDDHKL+L+EL KY DL++G + RA EIL R GPN +
Sbjct: 21 KKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNAL 80
Query: 89 TPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVV 148
TPPPTTPEW+KFC+QLFGGFS+LLW GAILCF+AYSIQ EEP DNLYL +VLS VV
Sbjct: 81 TPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVV 140
Query: 149 IVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVP 208
I+TGCFSYYQEAKSSKIMESFKNMVPQQALVIR GEKM IN +EVV+GDLVE+KGGDR+P
Sbjct: 141 IITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIP 200
Query: 209 ADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIA 268
ADLR+ISA GCKVDNSSLTGESEPQ+RSPDFT+ENPLETRNI FFSTNCVEGTARGIV+
Sbjct: 201 ADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVY 260
Query: 269 TGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEA 328
TGD TVMGRIA+L SGL GQTPIAAEIEHFIH+IT VAVFLGV+FF LSL+L Y WLEA
Sbjct: 261 TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEA 320
Query: 329 IIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388
+IFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT
Sbjct: 321 VIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448
LTQNRMTVAHMWFD ++EADTTE Q+G +F K+S TW L+RIAGLCNRA F+ANQE L
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 449 PIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQ 508
PI KRA GDASESALLK IE SV EMRE+ K+ EIPFNSTNKYQ+SIH ++S+
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSE 500
Query: 509 T-HVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNL 567
H+L+MKGAPERIL+ CS+ LL+G+E +++E+K+AFQNAYLELGGLGERVLGFC L L
Sbjct: 501 PQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFL 560
Query: 568 PSS-FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDH 626
P F +GF F+TD++NFP+DNLCFVGLISMIDPPRAAVPDAV KCRSAGIKVIMVTGDH
Sbjct: 561 PDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDH 620
Query: 627 PITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQ 686
PITAKAIAKGVGIISEG ET E++AARL IP+S+V+ AKA VVHG++LKD+ S+QLD
Sbjct: 621 PITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDD 680
Query: 687 ILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSD 746
IL+ H EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSD
Sbjct: 681 ILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSD 740
Query: 747 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPL 806
VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII IPL
Sbjct: 741 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPL 800
Query: 807 PLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI 866
PLGT+TILCIDLGTDMVPAISLAYE AESDIMKR PRNPKTD LVN RLI MAYGQIGMI
Sbjct: 801 PLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI 860
Query: 867 QALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQT 926
QAL GFFTYFVILAENGF P+ LLG+R+ W+D+++ND+EDSYGQQWTYEQRK+VEFTC T
Sbjct: 861 QALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHT 920
Query: 927 AFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRM 986
AFFV+IVVVQWADL+I KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGM VALRM
Sbjct: 921 AFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRM 980
Query: 987 YPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
YPLK TWW CA PYS+LIFVYDE+RKL+IR+ P GWVE+ETYY
Sbjct: 981 YPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 1606 bits (4158), Expect = 0.0
Identities = 797/1003 (79%), Positives = 890/1003 (88%), Gaps = 2/1003 (0%)
Query: 29 KMVKREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTV 88
K K+ K+ R+M+ELKKEV MDDHKL+L+EL KY DL++G + RA EIL R GPN +
Sbjct: 21 KKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNAL 80
Query: 89 TPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVV 148
TPPPTTPEW+KFC+QLFGGFS+LLW GAILCF+AYSIQ EEP DNLYL +VLS VV
Sbjct: 81 TPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVV 140
Query: 149 IVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVP 208
I+TGCFSYYQEAKSSKIMESFKNMVPQQALVIR GEKM IN +EVV+GDLVE+KGGDR+P
Sbjct: 141 IITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIP 200
Query: 209 ADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIA 268
ADLR+ISA GCKVDNSSLTGESEPQ+RSPDFT+ENPLETRNI FFSTNCVEGTARGIV+
Sbjct: 201 ADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVY 260
Query: 269 TGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEA 328
TGD TVMGRIA+L SGL GQTPIAAEIEHFIH+IT VAVFLGV+FF LSL+L Y WLEA
Sbjct: 261 TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEA 320
Query: 329 IIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388
+IFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT
Sbjct: 321 VIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448
LTQNRMTVAHMWFD ++EADTTE Q+G +F K+S TW L+RIAGLCNRA F+ANQE L
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 449 PIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQ 508
PI KRA GDASESALLK IE SV EMRE+ K+ EIPFNSTNKYQ+SIH ++S+
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSE 500
Query: 509 T-HVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNL 567
H+L+MKGAPERIL+ CS+ LL+G+E +++E+K+AFQNAYLELGGLGERVLGFC L L
Sbjct: 501 PQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFL 560
Query: 568 PSS-FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDH 626
P F +GF F+TD++NFP+DNLCFVGLISMIDPPRAAVPDAV KCRSAGIKVIMVTGDH
Sbjct: 561 PDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDH 620
Query: 627 PITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQ 686
PITAKAIAKGVGIISEG ET E++AARL IP+S+V+ AKA VVHG++LKD+ S+QLD
Sbjct: 621 PITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDD 680
Query: 687 ILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSD 746
IL+ H EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSD
Sbjct: 681 ILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSD 740
Query: 747 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPL 806
VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII IPL
Sbjct: 741 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPL 800
Query: 807 PLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI 866
PLGT+TILCIDLGTDMVPAISLAYE AESDIMKR PRNPKTD LVN RLI MAYGQIGMI
Sbjct: 801 PLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI 860
Query: 867 QALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQT 926
QAL GFFTYFVILAENGF P+ LLG+R+ W+D+++ND+EDSYGQQWTYEQRK+VEFTC T
Sbjct: 861 QALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHT 920
Query: 927 AFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRM 986
AFFV+IVVVQWADL+I KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGM VALRM
Sbjct: 921 AFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRM 980
Query: 987 YPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
YPLK TWW CA PYS+LIFVYDE+RKL+IR+ P GWVE+ETYY
Sbjct: 981 YPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
Length = 992
Score = 1599 bits (4141), Expect = 0.0
Identities = 793/992 (79%), Positives = 883/992 (89%), Gaps = 2/992 (0%)
Query: 40 MEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVK 99
M+ELKKEV MDDHKL+L+EL KY DL++G + RA EIL R GPN +TPPPTTPEW+K
Sbjct: 1 MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
Query: 100 FCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQE 159
FC+QLFGGFS+LLW GAILCF+AYSIQ EEP DNLYL +VLS VVI+TGCFSYYQE
Sbjct: 61 FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
Query: 160 AKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC 219
AKSSKIMESFKNMVPQQALVIR GEKM IN +EVV+GDLVE+KGGDR+PADLR+ISA GC
Sbjct: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
Query: 220 KVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIA 279
KVDNSSLTGESEPQ+RSPDFT+ENPLETRNI FFSTNCVEGTARGIV+ TGD TVMGRIA
Sbjct: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
Query: 280 SLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVAN 339
+L SGL GQTPIAAEIEHFIH+IT VAVFLGV+FF LSL+L Y WLEA+IFLIGIIVAN
Sbjct: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
Query: 340 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 399
VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
Query: 400 WFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDA 459
WFD ++EADTTE Q+G +F K+S TW L+RIAGLCNRA F+ANQE LPI KRA GDA
Sbjct: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
Query: 460 SESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQT-HVLMMKGAP 518
SESALLK IE SV EMRE+ K+ EIPFNSTNKYQ+SIH ++S+ H+L+MKGAP
Sbjct: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
Query: 519 ERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSS-FSKGFPF 577
ERIL+ CS+ LL+G+E +++E+K+AFQNAYLELGGLGERVLGFC L LP F +GF F
Sbjct: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
Query: 578 NTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGV 637
+TD++NFP+DNLCFVGLISMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
Query: 638 GIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFA 697
GIISEG ET E++AARL IP+S+V+ AKA VVHG++LKD+ S+QLD IL+ H EIVFA
Sbjct: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
Query: 698 RTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILL 757
RTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILL
Sbjct: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
Query: 758 DDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCID 817
DDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII IPLPLGT+TILCID
Sbjct: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
Query: 818 LGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFV 877
LGTDMVPAISLAYE AESDIMKR PRNPKTD LVN RLI MAYGQIGMIQAL GFFTYFV
Sbjct: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
Query: 878 ILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQW 937
ILAENGF P+ LLG+R+ W+D+++ND+EDSYGQQWTYEQRK+VEFTC TAFFV+IVVVQW
Sbjct: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
Query: 938 ADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCA 997
ADL+I KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGM VALRMYPLK TWW CA
Sbjct: 901 ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
Query: 998 IPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
PYS+LIFVYDE+RKL+IR+ P GWVE+ETYY
Sbjct: 961 FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 1589 bits (4114), Expect = 0.0
Identities = 787/997 (78%), Positives = 884/997 (88%), Gaps = 2/997 (0%)
Query: 35 KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94
K++R++++LKKEV M +HK+++EE+ KY+ D +G +H +A+EIL R GPN +TPPPTT
Sbjct: 17 KERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTT 76
Query: 95 PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154
PEWVKFC+QLFGGFS+LLW GAILCF+AY IQ ++P+ DNLYL IVL+ VVI+TGCF
Sbjct: 77 PEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCF 136
Query: 155 SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214
SYYQEAKSSKIMESFKNMVPQQALVIR GEKMQ+N +EVV+GDLVEIKGGDRVPADLR+I
Sbjct: 137 SYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRII 196
Query: 215 SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274
SA GCKVDNSSLTGESEPQ+RSPD TH+NPLETRNI FFSTNCVEGTARG+V+ATGD TV
Sbjct: 197 SAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTV 256
Query: 275 MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334
MGRIA+L SGL VG+TPIA EIEHFI LIT VAVFLGV+FF LSL+LGY WLEA+IFLIG
Sbjct: 257 MGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIG 316
Query: 335 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394
IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM
Sbjct: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376
Query: 395 TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454
TVAHMWFD ++EADTTE+Q+G +F KSS TW L+ IAGLCNRA FK Q+ +P+ KR
Sbjct: 377 TVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRD 436
Query: 455 TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQT-HVLM 513
GDASESALLK IE S SV MRE+N KVAEIPFNSTNKYQ+SIH ED + ++L+
Sbjct: 437 VAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLV 496
Query: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSS-FS 572
MKGAPERIL+ CST LL G+E +++EMKEAFQNAYLELGGLGERVLGFC LP F
Sbjct: 497 MKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFP 556
Query: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632
KGF F+ D++NF DNLCFVGL+SMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITAKA
Sbjct: 557 KGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 616
Query: 633 IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692
IAKGVGIISEG ET E++AARL IP+S+V+ AKA V+HG +LKD S+Q+D+ILQNH
Sbjct: 617 IAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHT 676
Query: 693 EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752
EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAA
Sbjct: 677 EIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAA 736
Query: 753 DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812
DMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FI+ IPLPLGTIT
Sbjct: 737 DMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTIT 796
Query: 813 ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872
ILCIDLGTDMVPAISLAYE+AESDIMKR PRNP+TD LVN RLI MAYGQIGMIQAL GF
Sbjct: 797 ILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGF 856
Query: 873 FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932
F+YFVILAENGF P +L+GIRL+W+D+ +NDLEDSYGQQWTYEQRKVVEFTC TAFFV+I
Sbjct: 857 FSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSI 916
Query: 933 VVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKIT 992
VVVQWADLII KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGMDVALRMYPLK +
Sbjct: 917 VVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPS 976
Query: 993 WWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
WW CA PYS LIFVYDEIRKL++R++P GWVE+ETYY
Sbjct: 977 WWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 1249 bits (3233), Expect = 0.0
Identities = 628/998 (62%), Positives = 779/998 (78%), Gaps = 3/998 (0%)
Query: 35 KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94
K+K + EE +KE+ +DDHKL+ EL KY D+ G S RA E+L R GPN++TPP T
Sbjct: 42 KKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQT 101
Query: 95 PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154
PE VKF KQ+ GGFS+LLW GA LC++AY IQ ++ + +N+YL VL +VVI+TG F
Sbjct: 102 PEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIF 161
Query: 155 SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214
+YYQEAKS+ IM SF M+PQQALVIR EK I +++V+GD+VE+KGGD++PAD+R++
Sbjct: 162 AYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVL 221
Query: 215 SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274
S+QGC+VDNSSLTGESEPQ RS +FTHENPLET+NICF+ST C+EGT G+VI TGD T+
Sbjct: 222 SSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTI 281
Query: 275 MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334
+G IASL SG+ +TPIA EIEHF+H++ VAV +G+ FF +++ L Y L++IIFLIG
Sbjct: 282 IGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIG 341
Query: 335 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394
IIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETLGSTS ICSDKTGTLTQNRM
Sbjct: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
Query: 395 TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454
TVAH+WFD ++ ADT+E+ + + F +SS TW L++I LCNRA+FK QE +PI K+A
Sbjct: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKA 461
Query: 455 TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLM- 513
GDASE+ALLKF E V E+R++N KVAEIPFNSTNK+Q+SIH +D LM
Sbjct: 462 VIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMV 521
Query: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-SFS 572
MKGAPERILE CST ++NG+E+ ++ + F AY+ELGGLGERVLGFC L LP+ F
Sbjct: 522 MKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFP 581
Query: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632
+ + F+ D +NFP NLCFVGL+SMIDPPR+ VPDAV+KCRSAGIKVIMVTGDHPITAKA
Sbjct: 582 ETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKA 641
Query: 633 IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692
IAK VGIIS +ET E++A RL I + +V+ AKA VV G ELKD+ S+QLD+IL N+
Sbjct: 642 IAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQ 701
Query: 693 EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752
EIVFARTSPQQKLIIVEGCQR AVVAVTGDGVNDSPALKKADIGIAMGI+GSD +K AA
Sbjct: 702 EIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAA 761
Query: 753 DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812
DM+LLDDNFASIVTGVEEGRLIFDNLKK+I Y+LT NI E+ PFL++II+G+PLP+GTIT
Sbjct: 762 DMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTIT 821
Query: 813 ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872
IL IDLGTD++P+I+LAYE AESDIM R PR+ D LVN L +Y IG++QAL F
Sbjct: 822 ILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAF 881
Query: 873 FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932
YF + A+ GF P L+ +R+ WE Y+NDL+DSYGQ+WT QR+ +E+T TAFFV I
Sbjct: 882 LVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGI 941
Query: 933 VVVQWADLIISKTRRNSLFQQGM-RNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKI 991
+V Q ADLII KTRRNS+FQQG+ RNKV+ GI + ++ LSY G AL L+
Sbjct: 942 LVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRA 1001
Query: 992 TWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
+W A+P++ILI+VYDE+RKL IR +P W ++ YY
Sbjct: 1002 QYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 1246 bits (3224), Expect = 0.0
Identities = 609/998 (61%), Positives = 770/998 (77%), Gaps = 3/998 (0%)
Query: 35 KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94
K+K +E +KKE+ ++DH+L++ EL KY TKG S A E+L R GPN + PP T
Sbjct: 38 KRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGT 97
Query: 95 PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154
PE+VKF +QL GG L+W A +C +A++IQ + T DNLYL+I L VV+VTGCF
Sbjct: 98 PEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCF 157
Query: 155 SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214
YYQE KS+ I+ SFKN+VPQQA VIR G+K QIN ++V+GDLVE+KGGDRVPAD+R++
Sbjct: 158 GYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRIL 217
Query: 215 SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274
+AQGCKVDNSSLTGESEPQ+RSP+ THE+PLETRNI FFST C+EGT +G+V+ TGD T+
Sbjct: 218 AAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTI 277
Query: 275 MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334
+GRIASL SG+ +TPIA EIEHF+ +I +A+ G TFF +++ +GY +L A++F +
Sbjct: 278 IGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMA 337
Query: 335 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394
I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRM
Sbjct: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
Query: 395 TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454
TV+H+WFD ++ ADTTE+Q+G+TF +SS+TW L R+ LCNRA FK+ Q+ +P+ KR
Sbjct: 398 TVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRI 457
Query: 455 TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLRED-SSQTHVLM 513
GDASE+ALLKF E + + R++ PKV EIPFNSTNK+Q+SIH ED H+L+
Sbjct: 458 VIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLV 517
Query: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNL-PSSFS 572
MKGAPER+LE CS+ L+ GQE ++++ +EAFQ AYL LGGLGERVLGFC L L +
Sbjct: 518 MKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYP 577
Query: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632
G+ F+ + +NFP LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKA
Sbjct: 578 PGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKA 637
Query: 633 IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692
IA VGIISEG+ET E++AARL++P+ +V+ A+A V++G +LKD+ +L + L+ HP
Sbjct: 638 IAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHP 697
Query: 693 EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752
E+VFARTSPQQKL+IVE CQRLGA+VAVTGDGVNDSPALKKADIG+AMGI+GSD +K AA
Sbjct: 698 EMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAA 757
Query: 753 DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812
DMILLDDNFASIVTGVE+GRLIFDNLKKSI YTLT NIPE+TP+L++I + +PLPLG IT
Sbjct: 758 DMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCIT 817
Query: 813 ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872
IL I+L TD+ P++SLAYE AESDIM PRNPK D LVN L +Y QIG IQ+ AGF
Sbjct: 818 ILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGF 877
Query: 873 FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932
YF +A+ G+ P+ +G+R WED +L DL+DSYGQ+WT+ QR ++TC T FF++I
Sbjct: 878 TDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISI 937
Query: 933 VVVQWADLIISKTRRNSLFQQG-MRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKI 991
V Q AD++I KTRR S FQQG RNK+L+ I+ + + FL Y PGM P++
Sbjct: 938 EVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRF 997
Query: 992 TWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
WWL +PY ILIFVYDEIRKL +R P W ++E YY
Sbjct: 998 QWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 378 bits (971), Expect = e-104
Identities = 314/1040 (30%), Positives = 488/1040 (46%), Gaps = 126/1040 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H L ++ +SV G S + R GPN + W +Q +
Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A++ FV +F E E T +V+ ++++ +QE + +E+ K
Sbjct: 65 LLLAALVSFVL----AWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ VIR K +I +++V GD+VE+ GD+VPADLRLI + +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES ++ PD N + +N+ F TN G A G+ +ATG T +G+I S
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239
Query: 283 SGLAVGQTPIAAEIEHF----IHLITVVAV---FLGVTFFALSLLLGYGWLEAIIFL--- 332
+ + +TP+ +++ F H I+V+ V + + FA G WL ++
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFA-DPAHGGSWLRGAVYYFKI 298
Query: 333 -IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391
+ + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 392 NRMTVAHMWFDMTVYEADTTE------EQTGKTFTKSS--------------DTWFMLAR 431
N+M+V M+ V EAD +G T+T D LA
Sbjct: 359 NQMSVCRMF---VVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELAT 415
Query: 432 IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKN 482
I LCN + N+ K G+A+E+AL +E Q+ S V N
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472
Query: 483 PKVAEIPFN------STNKYQMSIHLR----EDSSQTHVLMMKGAPERILEFCSTFLLNG 532
+ ++ S ++ MS++ + Q + +KGAPE ++E CS+ +
Sbjct: 473 TVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS 532
Query: 533 QEYSMNDEMKEAFQNAYLELGGLGE--RVLGFCFLNLP--------SSFSKGFPFNTDEI 582
+ + +E + G + R L + P SK + TD
Sbjct: 533 RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-- 590
Query: 583 NFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISE 642
L FVG + M+DPPR V +++C AGI+V+M+TGD+ TA AI + +GI +
Sbjct: 591 ------LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD 644
Query: 643 GTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQ 702
E+VA + G E D+ +Q Q + FAR P
Sbjct: 645 ----TEDVAGK----------------AYTGREFDDLSPEQQRQACRTAR--CFARVEPA 682
Query: 703 QKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFA 762
K IVE Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFA
Sbjct: 683 HKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFA 741
Query: 763 SIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDM 822
SIV VEEGR I+ N+K+ I Y ++SN+ E+ + ILG+P L + +L ++L TD
Sbjct: 742 SIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDG 801
Query: 823 VPAISLAYESAESDIMKRLPRNPKTDNLVNHRLI--GMAYGQIGMIQALAGFFTYFVILA 880
+PA +L + + DIM++LPR+P+ + L++ L +A G + +A +FV A
Sbjct: 802 LPATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDA 860
Query: 881 ENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVV-VQWAD 939
E I + +L ED+ + +V E T ++++V ++ +
Sbjct: 861 EGPH-------INFYQLRNFLKCSEDN--PLFAGIDCEVFESRFPTTMALSVLVTIEMCN 911
Query: 940 LIISKTRRNSLFQQ-GMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAI 998
+ S + SL + N L+ + L + P + + ++ PL W+ +
Sbjct: 912 ALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVL 971
Query: 999 PYSILIFVYDEIRKLLIRQH 1018
S+ + + DE K L R H
Sbjct: 972 QISLPVILLDEALKYLSRNH 991
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 372 bits (956), Expect = e-103
Identities = 302/1031 (29%), Positives = 486/1031 (47%), Gaps = 109/1031 (10%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H T+EE+ + V+ + G S ++ K++ R G N + E + + F L
Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELP----AEEGKTLLELVIEQFEDL 60
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L +L + +F E E T V+ ++++ +QE + +E+ K
Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ V R K +I +++V GD+VEI GD+VPAD+RL S + +VD S L
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRSPDFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTS 283
TGES + D + + +N+ F TN G A G+V+ATG +T +G+I
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240
Query: 284 GLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL----I 333
+TP+ +++ F ++ V + + + +++ + G W+ I+ +
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300
Query: 334 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 393
+ VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 394 MTVAHMWFDMTVYEADTTEEQ----TGKTFTKSS--------------DTWFMLARIAGL 435
M+V M F + E DT TG T+ D LA I L
Sbjct: 361 MSVCRM-FILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419
Query: 436 CNRADFKANQEILPIAKRATTGDASESAL----------------LKFIEQSYSSVAEMR 479
CN + N+ K G+A+E+AL L IE++ + + ++
Sbjct: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476
Query: 480 EKNPKVAEIPFNSTNKYQMSIHLREDS-SQTHV--LMMKGAPERILEFCSTFLLNGQEYS 536
+ K + F+ K MS++ + S+T + + +KGAPE +++ C+ + +
Sbjct: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535
Query: 537 MNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPM--DNLCFVGL 594
M +K+ + E G + + + + D NF NL FVG
Sbjct: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGC 595
Query: 595 ISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARL 654
+ M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + +
Sbjct: 596 VGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT-- 653
Query: 655 KIPISKVDASAAKAIVVHGAELKDIQ-SKQLDQILQNHPEIVFARTSPQQKLIIVEGCQR 713
G E ++ S Q D L FAR P K IVE Q
Sbjct: 654 ------------------GREFDELNPSAQRDACLNAR---CFARVEPSHKSKIVEFLQS 692
Query: 714 LGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRL 773
+ A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR
Sbjct: 693 FDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRA 751
Query: 774 IFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESA 833
I++N+K+ I Y ++SN+ E+ + LG P L + +L ++L TD +PA +L +
Sbjct: 752 IYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPP 811
Query: 834 ESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI--QALAGFFTYFVILAENGFRPVDLLG 891
+ DIM + PRNPK + L++ L Y IG A G ++ I A+ G R
Sbjct: 812 DLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR------ 863
Query: 892 IRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC---QTAFFVTIVVVQWADLIISKTRRN 948
+ + +L ED+ +E F T +V ++ + + S +
Sbjct: 864 VSFYQLSHFLQCKEDNP----DFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQ 919
Query: 949 SLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCAIPYSILIFVY 1007
SL + + + G + ++ FL Y + + ++ PL +T WL + S+ + +
Sbjct: 920 SLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILM 979
Query: 1008 DEIRKLLIRQH 1018
DE K + R +
Sbjct: 980 DETLKFVARNY 990
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 372 bits (956), Expect = e-103
Identities = 302/1031 (29%), Positives = 486/1031 (47%), Gaps = 109/1031 (10%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H T+EE+ + V+ + G S ++ K++ R G N + E + + F L
Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELP----AEEGKTLLELVIEQFEDL 60
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L +L + +F E E T V+ ++++ +QE + +E+ K
Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ V R K +I +++V GD+VEI GD+VPAD+RL S + +VD S L
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRSPDFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTS 283
TGES + D + + +N+ F TN G A G+V+ATG +T +G+I
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240
Query: 284 GLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL----I 333
+TP+ +++ F ++ V + + + +++ + G W+ I+ +
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300
Query: 334 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 393
+ VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
Query: 394 MTVAHMWFDMTVYEADTTEEQ----TGKTFTKSS--------------DTWFMLARIAGL 435
M+V M F + E DT TG T+ D LA I L
Sbjct: 361 MSVCRM-FILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419
Query: 436 CNRADFKANQEILPIAKRATTGDASESAL----------------LKFIEQSYSSVAEMR 479
CN + N+ K G+A+E+AL L IE++ + + ++
Sbjct: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476
Query: 480 EKNPKVAEIPFNSTNKYQMSIHLREDS-SQTHV--LMMKGAPERILEFCSTFLLNGQEYS 536
+ K + F+ K MS++ + S+T + + +KGAPE +++ C+ + +
Sbjct: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535
Query: 537 MNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPM--DNLCFVGL 594
M +K+ + E G + + + + D NF NL FVG
Sbjct: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGC 595
Query: 595 ISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARL 654
+ M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + +
Sbjct: 596 VGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT-- 653
Query: 655 KIPISKVDASAAKAIVVHGAELKDIQ-SKQLDQILQNHPEIVFARTSPQQKLIIVEGCQR 713
G E ++ S Q D L FAR P K IVE Q
Sbjct: 654 ------------------GREFDELNPSAQRDACLNAR---CFARVEPSHKSKIVEFLQS 692
Query: 714 LGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRL 773
+ A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR
Sbjct: 693 FDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRA 751
Query: 774 IFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESA 833
I++N+K+ I Y ++SN+ E+ + LG P L + +L ++L TD +PA +L +
Sbjct: 752 IYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPP 811
Query: 834 ESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI--QALAGFFTYFVILAENGFRPVDLLG 891
+ DIM + PRNPK + L++ L Y IG A G ++ I A+ G R
Sbjct: 812 DLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR------ 863
Query: 892 IRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC---QTAFFVTIVVVQWADLIISKTRRN 948
+ + +L ED+ +E F T +V ++ + + S +
Sbjct: 864 VSFYQLSHFLQCKEDNP----DFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQ 919
Query: 949 SLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCAIPYSILIFVY 1007
SL + + + G + ++ FL Y + + ++ PL +T WL + S+ + +
Sbjct: 920 SLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILM 979
Query: 1008 DEIRKLLIRQH 1018
DE K + R +
Sbjct: 980 DETLKFVARNY 990
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
sapiens]
Length = 994
Score = 365 bits (938), Expect = e-101
Identities = 297/1044 (28%), Positives = 476/1044 (45%), Gaps = 128/1044 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H T EE + V T G + + K L + G N + W +Q +
Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A + FV +F E E T V+ +++I +QE + +E+ K
Sbjct: 65 LLLAACISFVL----AWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ V R K +I +++V GD+VE+ GD+VPAD+R+++ + +VD S L
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES + PD N + +N+ F TN G A GIV TG T +G+I
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
Query: 283 SGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL---- 332
+ +TP+ +++ F ++ V + V + +++ + G W I+
Sbjct: 240 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
Query: 333 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 392
+ + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
Query: 393 RMTVAHMWFDMTVYEAD----TTEEQTGKTFTKSS--------------DTWFMLARIAG 434
+M+V M F + + D TG T+ D LA I
Sbjct: 360 QMSVCKM-FIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICA 418
Query: 435 LCNRADFKANQEILPIAKRATTGDASESALLKFIEQ---------SYSSVAEMREKNPKV 485
LCN + N+ K G+A+E+AL +E+ S S V N +
Sbjct: 419 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVI 475
Query: 486 AEIPFN------STNKYQMSIHLREDSSQT----HVLMMKGAPERILEFCSTFLLNGQEY 535
++ S ++ MS++ S + + +KGAPE +++ C+ +
Sbjct: 476 RQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRV 535
Query: 536 SMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDE----INFPMDNLCF 591
+ +KE A ++ G G L L + K D+ + + D L F
Sbjct: 536 PLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTF 593
Query: 592 VGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVA 651
VG++ M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E E A+
Sbjct: 594 VGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAY 653
Query: 652 ARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGC 711
G E D+ + + + FAR P K IVE
Sbjct: 654 T--------------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYL 691
Query: 712 QRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEG 771
Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEG
Sbjct: 692 QSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 750
Query: 772 RLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYE 831
R I++N+K+ I Y ++SN+ E+ + LG+P L + +L ++L TD +PA +L +
Sbjct: 751 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFN 810
Query: 832 SAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLG 891
+ DIM R PR+PK + L + +F +A G+ +G
Sbjct: 811 PPDLDIMDRPPRSPK--------------------EPLISGWLFFRYMAIGGYVGAATVG 850
Query: 892 IRLHW-----EDKYLNDLEDSYGQQWTYEQRKVVEFTCQ--------TAFFVTIVVVQWA 938
W + ++N + ++ Q T + C+ T +V ++
Sbjct: 851 AAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMC 910
Query: 939 DLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCA 997
+ + S + SL + + + G + ++ FL Y + + ++ L +T WL
Sbjct: 911 NALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMV 970
Query: 998 IPYSILIFVYDEIRKLLIRQHPDG 1021
+ S+ + DEI K + R + +G
Sbjct: 971 LKISLPVIGLDEILKFVARNYLEG 994
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
sapiens]
Length = 1001
Score = 363 bits (933), Expect = e-100
Identities = 296/1041 (28%), Positives = 474/1041 (45%), Gaps = 128/1041 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H T EE + V T G + + K L + G N + W +Q +
Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L A + FV +F E E T V+ +++I +QE + +E+ K
Sbjct: 65 LLLAACISFVL----AWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226
P+ V R K +I +++V GD+VE+ GD+VPAD+R+++ + +VD S L
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
Query: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282
TGES + PD N + +N+ F TN G A GIV TG T +G+I
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
Query: 283 SGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL---- 332
+ +TP+ +++ F ++ V + V + +++ + G W I+
Sbjct: 240 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
Query: 333 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 392
+ + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
Query: 393 RMTVAHMWFDMTVYEAD----TTEEQTGKTFTKSS--------------DTWFMLARIAG 434
+M+V M F + + D TG T+ D LA I
Sbjct: 360 QMSVCKM-FIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICA 418
Query: 435 LCNRADFKANQEILPIAKRATTGDASESALLKFIEQ---------SYSSVAEMREKNPKV 485
LCN + N+ K G+A+E+AL +E+ S S V N +
Sbjct: 419 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVI 475
Query: 486 AEIPFN------STNKYQMSIHLREDSSQT----HVLMMKGAPERILEFCSTFLLNGQEY 535
++ S ++ MS++ S + + +KGAPE +++ C+ +
Sbjct: 476 RQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRV 535
Query: 536 SMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDE----INFPMDNLCF 591
+ +KE A ++ G G L L + K D+ + + D L F
Sbjct: 536 PLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTF 593
Query: 592 VGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVA 651
VG++ M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E E A+
Sbjct: 594 VGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAY 653
Query: 652 ARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGC 711
G E D+ + + + FAR P K IVE
Sbjct: 654 T--------------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYL 691
Query: 712 QRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEG 771
Q + A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEG
Sbjct: 692 QSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 750
Query: 772 RLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYE 831
R I++N+K+ I Y ++SN+ E+ + LG+P L + +L ++L TD +PA +L +
Sbjct: 751 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFN 810
Query: 832 SAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLG 891
+ DIM R PR+PK + L + +F +A G+ +G
Sbjct: 811 PPDLDIMDRPPRSPK--------------------EPLISGWLFFRYMAIGGYVGAATVG 850
Query: 892 IRLHW-----EDKYLNDLEDSYGQQWTYEQRKVVEFTCQ--------TAFFVTIVVVQWA 938
W + ++N + ++ Q T + C+ T +V ++
Sbjct: 851 AAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMC 910
Query: 939 DLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCA 997
+ + S + SL + + + G + ++ FL Y + + ++ L +T WL
Sbjct: 911 NALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMV 970
Query: 998 IPYSILIFVYDEIRKLLIRQH 1018
+ S+ + DEI K + R +
Sbjct: 971 LKISLPVIGLDEILKFVARNY 991
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
sapiens]
Length = 939
Score = 363 bits (932), Expect = e-100
Identities = 258/850 (30%), Positives = 422/850 (49%), Gaps = 84/850 (9%)
Query: 53 KLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLL 112
+L + E+++ DL G + G N P W K+ Q +LL
Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
Query: 113 WTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNM 172
A++ + + F++ +SI ++++++VT F QE +S K +E +
Sbjct: 88 LASAVISVLMHQ----FDDA-------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
Query: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEP 232
VP + +R G+ +++V GD V + GDRVPADLRL A +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
Query: 233 QSR----SPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288
S+ P T+ + NI F T G A+G+VI TG+++ G + +
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
Query: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATV 348
+TP+ ++ ++ + + + LLG LE + + VA +PEGL V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
Query: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408
TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ ++
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA- 373
Query: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFK-------ANQEILPIAKRATTGDASE 461
E TG + + + + G N A + N + I G +E
Sbjct: 374 ----EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV--IRNNTLMGKPTE 427
Query: 462 SALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQM--SIHLREDSSQTHVLMMKGAPE 519
AL+ + + +++ + AE PF+S K+ +H R + + MKGA E
Sbjct: 428 GALIALAMKM--GLDGLQQDYIRKAEYPFSSEQKWMAVKCVH-RTQQDRPEICFMKGAYE 484
Query: 520 RILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNT 579
+++++C+T+ GQ ++ + ++ +Q +G G RVL L S G
Sbjct: 485 QVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGPELG----- 534
Query: 580 DEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGI 639
L F+GL+ +IDPPR V +AV+ ++G+ + M+TGD TA AIA +G+
Sbjct: 535 --------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
Query: 640 ISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFAR 698
S+ +++ V G E+ + +QL QI+ P++ VF R
Sbjct: 587 YSKTSQS------------------------VSGEEIDAMDVQQLSQIV---PKVAVFYR 619
Query: 699 TSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLD 758
SP+ K+ I++ Q+ G+VVA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+D
Sbjct: 620 ASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVD 679
Query: 759 DNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818
D+F +I++ +EEG+ I++N+K + + L+++I +T + ++ P PL + IL I++
Sbjct: 680 DDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINI 739
Query: 819 GTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVI 878
D PA SL E + D++++ PRN K L + ++ + I I F ++
Sbjct: 740 IMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWRE 797
Query: 879 LAENGFRPVD 888
L +N P D
Sbjct: 798 LRDNVITPRD 807
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
sapiens]
Length = 949
Score = 363 bits (932), Expect = e-100
Identities = 258/850 (30%), Positives = 422/850 (49%), Gaps = 84/850 (9%)
Query: 53 KLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLL 112
+L + E+++ DL G + G N P W K+ Q +LL
Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
Query: 113 WTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNM 172
A++ + + F++ +SI ++++++VT F QE +S K +E +
Sbjct: 88 LASAVISVLMHQ----FDDA-------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
Query: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEP 232
VP + +R G+ +++V GD V + GDRVPADLRL A +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
Query: 233 QSR----SPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288
S+ P T+ + NI F T G A+G+VI TG+++ G + +
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
Query: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATV 348
+TP+ ++ ++ + + + LLG LE + + VA +PEGL V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
Query: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408
TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ ++
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA- 373
Query: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFK-------ANQEILPIAKRATTGDASE 461
E TG + + + + G N A + N + I G +E
Sbjct: 374 ----EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV--IRNNTLMGKPTE 427
Query: 462 SALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQM--SIHLREDSSQTHVLMMKGAPE 519
AL+ + + +++ + AE PF+S K+ +H R + + MKGA E
Sbjct: 428 GALIALAMKM--GLDGLQQDYIRKAEYPFSSEQKWMAVKCVH-RTQQDRPEICFMKGAYE 484
Query: 520 RILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNT 579
+++++C+T+ GQ ++ + ++ +Q +G G RVL L S G
Sbjct: 485 QVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGPELG----- 534
Query: 580 DEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGI 639
L F+GL+ +IDPPR V +AV+ ++G+ + M+TGD TA AIA +G+
Sbjct: 535 --------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
Query: 640 ISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFAR 698
S+ +++ V G E+ + +QL QI+ P++ VF R
Sbjct: 587 YSKTSQS------------------------VSGEEIDAMDVQQLSQIV---PKVAVFYR 619
Query: 699 TSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLD 758
SP+ K+ I++ Q+ G+VVA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+D
Sbjct: 620 ASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVD 679
Query: 759 DNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818
D+F +I++ +EEG+ I++N+K + + L+++I +T + ++ P PL + IL I++
Sbjct: 680 DDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINI 739
Query: 819 GTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVI 878
D PA SL E + D++++ PRN K L + ++ + I I F ++
Sbjct: 740 IMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWRE 797
Query: 879 LAENGFRPVD 888
L +N P D
Sbjct: 798 LRDNVITPRD 807
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
sapiens]
Length = 888
Score = 363 bits (932), Expect = e-100
Identities = 258/850 (30%), Positives = 422/850 (49%), Gaps = 84/850 (9%)
Query: 53 KLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLL 112
+L + E+++ DL G + G N P W K+ Q +LL
Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
Query: 113 WTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNM 172
A++ + + F++ +SI ++++++VT F QE +S K +E +
Sbjct: 88 LASAVISVLMHQ----FDDA-------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
Query: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEP 232
VP + +R G+ +++V GD V + GDRVPADLRL A +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
Query: 233 QSR----SPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288
S+ P T+ + NI F T G A+G+VI TG+++ G + +
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
Query: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATV 348
+TP+ ++ ++ + + + LLG LE + + VA +PEGL V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
Query: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408
TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ ++
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA- 373
Query: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFK-------ANQEILPIAKRATTGDASE 461
E TG + + + + G N A + N + I G +E
Sbjct: 374 ----EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV--IRNNTLMGKPTE 427
Query: 462 SALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQM--SIHLREDSSQTHVLMMKGAPE 519
AL+ + + +++ + AE PF+S K+ +H R + + MKGA E
Sbjct: 428 GALIALAMKM--GLDGLQQDYIRKAEYPFSSEQKWMAVKCVH-RTQQDRPEICFMKGAYE 484
Query: 520 RILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNT 579
+++++C+T+ GQ ++ + ++ +Q +G G RVL L S G
Sbjct: 485 QVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGPELG----- 534
Query: 580 DEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGI 639
L F+GL+ +IDPPR V +AV+ ++G+ + M+TGD TA AIA +G+
Sbjct: 535 --------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
Query: 640 ISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFAR 698
S+ +++ V G E+ + +QL QI+ P++ VF R
Sbjct: 587 YSKTSQS------------------------VSGEEIDAMDVQQLSQIV---PKVAVFYR 619
Query: 699 TSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLD 758
SP+ K+ I++ Q+ G+VVA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+D
Sbjct: 620 ASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVD 679
Query: 759 DNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818
D+F +I++ +EEG+ I++N+K + + L+++I +T + ++ P PL + IL I++
Sbjct: 680 DDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINI 739
Query: 819 GTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVI 878
D PA SL E + D++++ PRN K L + ++ + I I F ++
Sbjct: 740 IMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWRE 797
Query: 879 LAENGFRPVD 888
L +N P D
Sbjct: 798 LRDNVITPRD 807
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
Length = 919
Score = 363 bits (932), Expect = e-100
Identities = 258/850 (30%), Positives = 422/850 (49%), Gaps = 84/850 (9%)
Query: 53 KLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLL 112
+L + E+++ DL G + G N P W K+ Q +LL
Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
Query: 113 WTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNM 172
A++ + + F++ +SI ++++++VT F QE +S K +E +
Sbjct: 88 LASAVISVLMHQ----FDDA-------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
Query: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEP 232
VP + +R G+ +++V GD V + GDRVPADLRL A +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
Query: 233 QSR----SPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288
S+ P T+ + NI F T G A+G+VI TG+++ G + +
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
Query: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATV 348
+TP+ ++ ++ + + + LLG LE + + VA +PEGL V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
Query: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408
TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ ++
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA- 373
Query: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFK-------ANQEILPIAKRATTGDASE 461
E TG + + + + G N A + N + I G +E
Sbjct: 374 ----EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV--IRNNTLMGKPTE 427
Query: 462 SALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQM--SIHLREDSSQTHVLMMKGAPE 519
AL+ + + +++ + AE PF+S K+ +H R + + MKGA E
Sbjct: 428 GALIALAMKM--GLDGLQQDYIRKAEYPFSSEQKWMAVKCVH-RTQQDRPEICFMKGAYE 484
Query: 520 RILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNT 579
+++++C+T+ GQ ++ + ++ +Q +G G RVL L S G
Sbjct: 485 QVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGPELG----- 534
Query: 580 DEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGI 639
L F+GL+ +IDPPR V +AV+ ++G+ + M+TGD TA AIA +G+
Sbjct: 535 --------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
Query: 640 ISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFAR 698
S+ +++ V G E+ + +QL QI+ P++ VF R
Sbjct: 587 YSKTSQS------------------------VSGEEIDAMDVQQLSQIV---PKVAVFYR 619
Query: 699 TSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLD 758
SP+ K+ I++ Q+ G+VVA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+D
Sbjct: 620 ASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVD 679
Query: 759 DNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818
D+F +I++ +EEG+ I++N+K + + L+++I +T + ++ P PL + IL I++
Sbjct: 680 DDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINI 739
Query: 819 GTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVI 878
D PA SL E + D++++ PRN K L + ++ + I I F ++
Sbjct: 740 IMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWRE 797
Query: 879 LAENGFRPVD 888
L +N P D
Sbjct: 798 LRDNVITPRD 807
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 345 bits (885), Expect = 1e-94
Identities = 260/850 (30%), Positives = 406/850 (47%), Gaps = 93/850 (10%)
Query: 27 KKKMVKREKQKRNMEELKKEVVMDDH---KLTLEELSTKYSVDLTKGHSHQRAKEILTRG 83
++ ++ + + + +E+ KK + K E+L+ + VDL G S +
Sbjct: 30 EEALIDEQSELKAIEKEKKVTALPPKEACKCQKEDLARAFCVDLHTGLSEFSVTQRRLAH 89
Query: 84 GPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIV 143
G N + P W K+ Q LLL A++ + + +SI
Sbjct: 90 GWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSVLTKEYEDA-----------VSIA 138
Query: 144 LSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKG 203
+V+V+VT F QE +S K +E MVP + +R G+ + +E+V GD+V +
Sbjct: 139 TAVLVVVTVAF--IQEYRSEKSLEELTKMVPPECNCLREGKLQHLLARELVPGDVVSLSI 196
Query: 204 GDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPD-FTHENPLET-RNICFFSTNCVEGT 261
GDR+PAD+RL VD SS TGE+EP S++ T L T NI F T G
Sbjct: 197 GDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGR 256
Query: 262 ARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLL 321
+G+VI TG+S+ G + + +TP+ ++ +T+ + F + L++
Sbjct: 257 GQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTLFS------FGIIGLIM 310
Query: 322 GYGWLEA----IIFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETL 375
GW + +F IG+ VA +PEGL V V L L RMA+K +VK L VETL
Sbjct: 311 LIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETL 370
Query: 376 GSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLAR---- 431
G S +CSDKTGTLT N MTV + V E +G + + ++
Sbjct: 371 GCCSVLCSDKTGTLTANEMTVTQL-----VTSDGLRAEVSGVGYDGQGTVCLLPSKEVIK 425
Query: 432 -----IAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVA 486
G A AN + I K A G +E AL+ + +++++ +
Sbjct: 426 EFSNVSVGKLVEAGCVANNAV--IRKNAVMGQPTEGALMALAMKM--DLSDIKNSYIRKK 481
Query: 487 EIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQ 546
EIPF+S K+ + Q + MKGA E ++ +C+ + G + + +
Sbjct: 482 EIPFSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGIPLPLTPQQRSFCL 541
Query: 547 NAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVP 606
+G LG RVL L S G L F+GL+ +IDPPR V
Sbjct: 542 QEEKRMGSLGLRVLA-----LASGPELG-------------RLTFLGLVGIIDPPRVGVK 583
Query: 607 DAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAA 666
+AV +G+ V M+TGD TA AI + +G+ +
Sbjct: 584 EAVQVLSESGVSVKMITGDALETALAIGRNIGLCN------------------------G 619
Query: 667 KAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVN 726
K + G E+ ++ +L + VF RTSP+ KL I++ Q GA+VA+TGDGVN
Sbjct: 620 KLQAMSGEEVDSVEKGELADRVGKVS--VFFRTSPKHKLKIIKALQESGAIVAMTGDGVN 677
Query: 727 DSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTL 786
D+ ALK ADIGIAMG +G+DVSK+AA+MIL+DD+F++I+ VEEG+ IF N+K + + L
Sbjct: 678 DAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQL 737
Query: 787 TSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPK 846
+++I ++ + + +P PL + IL I++ D PA SL E + D ++ PR+ +
Sbjct: 738 STSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVR 797
Query: 847 TDNLVNHRLI 856
D +++ LI
Sbjct: 798 -DTILSRALI 806
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
sapiens]
Length = 1015
Score = 343 bits (881), Expect = 4e-94
Identities = 290/1026 (28%), Positives = 473/1026 (46%), Gaps = 126/1026 (12%)
Query: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111
H T+EE+ + V+ + G S ++ K++ R G N + E + + F L
Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELP----AEEGKTLLELVIEQFEDL 60
Query: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170
L +L + +F E E T V+ ++++ +QE + +E+ K
Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120
Query: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTG 228
P+ V R K +I +++V GD+VEI G ++ S+
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162
Query: 229 ESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288
++P PD N + +N+ F TN G A G+V+ATG +T +G+I
Sbjct: 163 HTDPV---PDPRAVNQ-DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218
Query: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL----IGIIVA 338
+TP+ +++ F ++ V + + + +++ + G W+ I+ + + VA
Sbjct: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278
Query: 339 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 398
+PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V
Sbjct: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338
Query: 399 MWFDMTVYEADTTEEQ----TGKTFTKSS--------------DTWFMLARIAGLCNRAD 440
M F + E DT TG T+ D LA I LCN +
Sbjct: 339 M-FILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397
Query: 441 FKANQEILPIAKRATTGDASESAL----------------LKFIEQSYSSVAEMREKNPK 484
N+ K G+A+E+AL L IE++ + + +++ K
Sbjct: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454
Query: 485 VAEIPFNSTNKYQMSIHLREDS-SQTHV--LMMKGAPERILEFCSTFLLNGQEYSMNDEM 541
+ F+ K MS++ + S+T + + +KGAPE +++ C+ + + M +
Sbjct: 455 EFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513
Query: 542 KEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPM--DNLCFVGLISMID 599
K+ + E G + + + + D NF NL FVG + M+D
Sbjct: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573
Query: 600 PPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPIS 659
PPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + +
Sbjct: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT------- 626
Query: 660 KVDASAAKAIVVHGAELKDIQ-SKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVV 718
G E ++ S Q D L FAR P K IVE Q +
Sbjct: 627 -------------GREFDELNPSAQRDACLNAR---CFARVEPSHKSKIVEFLQSFDEIT 670
Query: 719 AVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNL 778
A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++N+
Sbjct: 671 AMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNM 729
Query: 779 KKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIM 838
K+ I Y ++SN+ E+ + LG P L + +L ++L TD +PA +L + + DIM
Sbjct: 730 KQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM 789
Query: 839 KRLPRNPKTDNLVNHRLIGMAYGQIGMI--QALAGFFTYFVILAENGFRPVDLLGIRLHW 896
+ PRNPK + L++ L Y IG A G ++ I A+ G R + +
Sbjct: 790 NKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR------VSFYQ 841
Query: 897 EDKYLNDLEDSYGQQWTYEQRKVVEFTC---QTAFFVTIVVVQWADLIISKTRRNSLFQQ 953
+L ED+ +E F T +V ++ + + S + SL +
Sbjct: 842 LSHFLQCKEDNP----DFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRM 897
Query: 954 GMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRK 1012
+ + G + ++ FL Y + + ++ PL +T WL + S+ + + DE K
Sbjct: 898 PPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLK 957
Query: 1013 LLIRQH 1018
+ R +
Sbjct: 958 FVARNY 963
>gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens]
Length = 165
Score = 342 bits (876), Expect = 1e-93
Identities = 165/165 (100%), Positives = 165/165 (100%)
Query: 865 MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 924
MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC
Sbjct: 1 MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 60
Query: 925 QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 984
QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL
Sbjct: 61 QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 120
Query: 985 RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029
RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY
Sbjct: 121 RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 165
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 262 bits (670), Expect = 1e-69
Identities = 240/815 (29%), Positives = 380/815 (46%), Gaps = 132/815 (16%)
Query: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
+I+LSV+ V++ F+ + + K + ++S + Q+ V+R G+ +QI V E+V+GD+
Sbjct: 156 AILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214
Query: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
++K GD +PAD I K+D SSLTGES+ +S D ++P+ T+ +E
Sbjct: 215 QVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVME 266
Query: 260 G------TARGIVIATGDS-TVMG----------RIASLTSGLAVGQ------------- 289
G TA G+ TG T++G + A G A +
Sbjct: 267 GSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDAD 326
Query: 290 -------------------TPIAAEIEHFIHLITVVAVFLGVTFFALSLLL--GYGWLEA 328
T +A +I +++ + V + V +F + + WL
Sbjct: 327 DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPE 386
Query: 329 I----------IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG 376
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G
Sbjct: 387 CTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMG 446
Query: 377 STSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLC 436
+ + ICSDKTGTLT NRMTV + Y D ++ + ++ T +L +
Sbjct: 447 NATAICSDKTGTLTTNRMTV------VQAYVGDVHYKEIPDPSSINTKTMELLINAIAIN 500
Query: 437 NRADFKANQEILPIAKRAT----TGDASESALLKFI---EQSYSSVAEMREKNPKVAEIP 489
+ K ILP K G+ +E LL F+ +Q Y V +
Sbjct: 501 SAYTTK----ILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYT 556
Query: 490 FNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSM--NDEMKEAFQN 547
FNS K ++ D S + KGA E +L+ C L E + + E +
Sbjct: 557 FNSVRKSMSTVIKLPDES--FRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKK 614
Query: 548 AYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPD 607
+ G R + + + PSS + D +N + +C VG+ DP R VP+
Sbjct: 615 VIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILN-ELTCICVVGI---EDPVRPEVPE 670
Query: 608 AVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDA 663
A+ KC+ AGI V MVTGD+ TA+AIA GII G + +E R++
Sbjct: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIR-------- 722
Query: 664 SAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGC-----QRLGAV 717
E +I+ +++D+I P++ V AR+SP K +V+G V
Sbjct: 723 ----------NEKGEIEQERIDKI---WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQV 769
Query: 718 VAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDN 777
VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDNF+SIV V GR ++D+
Sbjct: 770 VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDS 829
Query: 778 LKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDI 837
+ K + + LT N+ + + PL + +L ++L D +++LA E +
Sbjct: 830 ISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETL 889
Query: 838 MKRLP---RNPKTDNLVNHRLIGMAYGQIGMIQAL 869
+ R P P + ++G A Q+ +I L
Sbjct: 890 LLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 230 bits (587), Expect = 5e-60
Identities = 179/565 (31%), Positives = 282/565 (49%), Gaps = 64/565 (11%)
Query: 331 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
Query: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448
LT NRMTV + + Y+ E +++ I+ C +IL
Sbjct: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILS-----YLVTGISVNC-----AYTSKIL 529
Query: 449 PIAKRA----TTGDASESALLKFIEQSYSSVAEMREKNPKVA---EIPFNSTNKYQMSIH 501
P K G+ +E ALL + ++R + P+ A FNS K ++
Sbjct: 530 PPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVL 589
Query: 502 LREDSSQTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERV 559
D S + + KGA E IL+ C L NG+ ++ +E + G R
Sbjct: 590 KNSDGS--YRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRT 647
Query: 560 LGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKV 619
+ F + P+ + N ++I + L + ++ + DP R VPDA+ KC+ AGI V
Sbjct: 648 ICLAFRDFPAGEPEPEWDNENDI---VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 620 IMVTGDHPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDASAAKAIVVHGAE 675
MVTGD+ TA+AIA GI+ G + ++ R++ E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------------NE 746
Query: 676 LKDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGC-------QRLGAVVAVTGDGVND 727
+I+ +++D+I P++ V AR+SP K +V+G QR VVAVTGDG ND
Sbjct: 747 KGEIEQERIDKI---WPKLRVLARSSPTDKHTLVKGIIDSTVSDQR--QVVAVTGDGTND 801
Query: 728 SPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLT 787
PALKKAD+G AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 802 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 861
Query: 788 SNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RN 844
N+ + + PL + +L ++L D + +++LA E ++ R P
Sbjct: 862 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK 921
Query: 845 PKTDNLVNHRLIGMAYGQIGMIQAL 869
P + ++G A+ Q+ ++ L
Sbjct: 922 PLISRTMMKNILGHAFYQLVVVFTL 946
Score = 74.3 bits (181), Expect = 5e-13
Identities = 51/142 (35%), Positives = 84/142 (59%), Gaps = 10/142 (7%)
Query: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
+I+LSVV V++ F+ + + K + ++S + Q+ VIRGG+ +QI V ++ +GD+
Sbjct: 158 AILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQVIQIPVADITVGDIA 216
Query: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
++K GD +PAD LI K+D SSLTGES+ +S D ++PL T+ +E
Sbjct: 217 QVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL-----LLSGTHVME 268
Query: 260 GTARGIVIATGDSTVMGRIASL 281
G+ R +V A G ++ G I +L
Sbjct: 269 GSGRMVVTAVGVNSQTGIIFTL 290
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 230 bits (587), Expect = 5e-60
Identities = 179/565 (31%), Positives = 282/565 (49%), Gaps = 64/565 (11%)
Query: 331 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
Query: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448
LT NRMTV + + Y+ E +++ I+ C +IL
Sbjct: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILS-----YLVTGISVNC-----AYTSKIL 529
Query: 449 PIAKRA----TTGDASESALLKFIEQSYSSVAEMREKNPKVA---EIPFNSTNKYQMSIH 501
P K G+ +E ALL + ++R + P+ A FNS K ++
Sbjct: 530 PPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVL 589
Query: 502 LREDSSQTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERV 559
D S + + KGA E IL+ C L NG+ ++ +E + G R
Sbjct: 590 KNSDGS--YRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRT 647
Query: 560 LGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKV 619
+ F + P+ + N ++I + L + ++ + DP R VPDA+ KC+ AGI V
Sbjct: 648 ICLAFRDFPAGEPEPEWDNENDI---VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 620 IMVTGDHPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDASAAKAIVVHGAE 675
MVTGD+ TA+AIA GI+ G + ++ R++ E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------------NE 746
Query: 676 LKDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGC-------QRLGAVVAVTGDGVND 727
+I+ +++D+I P++ V AR+SP K +V+G QR VVAVTGDG ND
Sbjct: 747 KGEIEQERIDKI---WPKLRVLARSSPTDKHTLVKGIIDSTVSDQR--QVVAVTGDGTND 801
Query: 728 SPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLT 787
PALKKAD+G AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 802 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 861
Query: 788 SNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RN 844
N+ + + PL + +L ++L D + +++LA E ++ R P
Sbjct: 862 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK 921
Query: 845 PKTDNLVNHRLIGMAYGQIGMIQAL 869
P + ++G A+ Q+ ++ L
Sbjct: 922 PLISRTMMKNILGHAFYQLVVVFTL 946
Score = 74.3 bits (181), Expect = 5e-13
Identities = 51/142 (35%), Positives = 84/142 (59%), Gaps = 10/142 (7%)
Query: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
+I+LSVV V++ F+ + + K + ++S + Q+ VIRGG+ +QI V ++ +GD+
Sbjct: 158 AILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQVIQIPVADITVGDIA 216
Query: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
++K GD +PAD LI K+D SSLTGES+ +S D ++PL T+ +E
Sbjct: 217 QVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL-----LLSGTHVME 268
Query: 260 GTARGIVIATGDSTVMGRIASL 281
G+ R +V A G ++ G I +L
Sbjct: 269 GSGRMVVTAVGVNSQTGIIFTL 290
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 229 bits (584), Expect = 1e-59
Identities = 195/619 (31%), Positives = 300/619 (48%), Gaps = 79/619 (12%)
Query: 290 TPIAAEIEHFIHLITVVAVFLGVTFFALSLLL--GYGWLEAI----------IFLIGI-- 335
T +A +I +++ + V + V +F + + G WL F+IG+
Sbjct: 365 TKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTV 424
Query: 336 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 395
+V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT
Sbjct: 425 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMT 484
Query: 396 VAHMWFDMTVY-EADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454
V + T Y E T K +L + + K ILP K
Sbjct: 485 VVQSYLGDTHYKEIPAPSALTPKILD-------LLVHAISINSAYTTK----ILPPEKEG 533
Query: 455 T----TGDASESALLKFIEQSYSSVAEMREKNP--KVAEI-PFNSTNKYQMSIHLREDSS 507
G+ +E ALL F+ +RE+ P K+ ++ FNS K ++ D
Sbjct: 534 ALPRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGG 593
Query: 508 QTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERVLGFCFL 565
L KGA E +L+ C+ L NG+ ++ +E + G R + +
Sbjct: 594 FR--LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYR 651
Query: 566 NLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGD 625
+ FS G + D N + +L + ++ + DP R VP+A+ KC+ AGI V MVTGD
Sbjct: 652 D----FSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGD 707
Query: 626 HPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQS 681
+ TA+AIA GII G + +E R++ E +I+
Sbjct: 708 NINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIR------------------NEKGEIEQ 749
Query: 682 KQLDQILQNHPEI-VFARTSPQQKLIIVEGC-------QRLGAVVAVTGDGVNDSPALKK 733
++LD++ P++ V AR+SP K +V+G QR VVAVTGDG ND PALKK
Sbjct: 750 ERLDKVW---PKLRVLARSSPTDKHTLVKGIIDSTTGEQR--QVVAVTGDGTNDGPALKK 804
Query: 734 ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEI 793
AD+G AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ +
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864
Query: 794 TPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RNPKTDNL 850
+ PL + +L ++L D +++LA E ++ R P P
Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924
Query: 851 VNHRLIGMAYGQIGMIQAL 869
+ ++G A Q+ +I L
Sbjct: 925 MMKNILGHAVYQLAIIFTL 943
Score = 72.4 bits (176), Expect = 2e-12
Identities = 49/142 (34%), Positives = 84/142 (59%), Gaps = 10/142 (7%)
Query: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
+I+LSV+ V++ F+ + + K + ++S + Q+ VIR G+ +Q+ V +V+GD+
Sbjct: 159 AILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRNGQLLQVPVAALVVGDIA 217
Query: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
++K GD +PAD LI A K+D SSLTGES+ +S D ++P+ T+ +E
Sbjct: 218 QVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVME 269
Query: 260 GTARGIVIATGDSTVMGRIASL 281
G+ R +V A G ++ G I +L
Sbjct: 270 GSGRMVVTAVGVNSQTGIIFTL 291
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,999,933
Number of Sequences: 37866
Number of extensions: 1541051
Number of successful extensions: 4972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 4628
Number of HSP's gapped (non-prelim): 169
length of query: 1029
length of database: 18,247,518
effective HSP length: 112
effective length of query: 917
effective length of database: 14,006,526
effective search space: 12843984342
effective search space used: 12843984342
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.