Guide to the Human Genome
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Name: PDGFA Sequence: fasta or formatted (196aa) NCBI GI: 15208656
Description:

platelet-derived growth factor alpha isoform 2 preproprotein

Referenced in:

Platelets and Megakaryocytes

Other entries for this name:
alt prot [211aa] platelet-derived growth factor alpha isoform 1 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         13           1
 C cysteine            5.1         10           2
 D aspartate           4.1          8           1
 E glutamate           9.7         19           2
 F phenylalanine       0.5          1           1
 G glycine             2.6          5           1
 H histidine           4.1          8           2
 I isoleucine          5.1         10           1
 K lysine              6.1         12           2
 L leucine             9.7         19           4
 M methionine          0.5          1           1
 N asparagine          1.5          3           1
 P proline             6.1         12           2
 Q glutamine           2.6          5           1
 R arginine           10.2         20           2
 S serine              7.1         14           2
 T threonine           5.6         11           2
 V valine             10.2         20           1
 W tryptophan          0.5          1           1
 Y tyrosine            2.0          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   platelet-derived growth factor alpha isoform 2 prepr... 
PDGFA                 0.984   platelet-derived growth factor alpha isoform 1 prepr...
PDGFB                 0.327   platelet-derived growth factor beta isoform 1 preprop...
PDGFB                 0.306   platelet-derived growth factor beta isoform 2 prepro...
VEGFB                 0.067   vascular endothelial growth factor B 
FIGF                  0.056   vascular endothelial growth factor D preproprotein [H...
PGF                   0.054   placental growth factor, vascular endothelial growth...
VEGFC                 0.048   vascular endothelial growth factor C preproprotein [H...
PDGFC                 0.040   platelet-derived growth factor C precursor 
VEGFA                 0.038   vascular endothelial growth factor A isoform f precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform e precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform d precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform c precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform b precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform a precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform g precu...
PDGFD                 0.029   platelet derived growth factor D isoform 1 precursor...
PDGFD                 0.029   platelet derived growth factor D isoform 2 precursor...
APC2                  0.016   adenomatosis polyposis coli 2 
C1orf68               0.013   skin-specific protein 32 
TBCKL                 0.011   TBC domain-containing protein kinase-like 
NF2                   0.008   neurofibromin 2 isoform 7 
NF2                   0.008   neurofibromin 2 isoform 2 
NF2                   0.008   neurofibromin 2 isoform 2 
NF2                   0.008   neurofibromin 2 isoform 7 
NF2                   0.008   neurofibromin 2 isoform 6 
NF2                   0.008   neurofibromin 2 isoform 5 
NF2                   0.008   neurofibromin 2 isoform 2 
NF2                   0.008   neurofibromin 2 isoform 1 
SLIT3                 0.008   slit homolog 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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