Guide to the Human Genome
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Search of human proteins with 149158698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149158698 major histocompatibility complex, class I, F
isoform 2 precursor [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149158698 major histocompatibility complex, class I, F isofor...   717   0.0  
gi|149158702 major histocompatibility complex, class I, F isofor...   715   0.0  
gi|24797067 major histocompatibility complex, class I, A precurs...   577   e-165
gi|17986001 major histocompatibility complex, class I, B precurs...   567   e-162
gi|4504415 major histocompatibility complex, class I, G precurso...   553   e-158
gi|52630342 major histocompatibility complex, class I, C precurs...   549   e-156
gi|62912479 major histocompatibility complex, class I, E precurs...   520   e-148
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi...   455   e-128
gi|149158700 major histocompatibility complex, class I, F isofor...   421   e-118
gi|4504417 major histocompatibility complex, class I-related [Ho...   222   4e-58
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap...   202   3e-52
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]                191   6e-49
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa...   189   4e-48
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa...   186   3e-47
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa...   166   2e-41
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa...   149   3e-36
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H...   140   1e-33
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom...   140   1e-33
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi...   140   2e-33
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa...   137   1e-32
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s...   116   3e-26
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa...   116   3e-26
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa...   108   5e-24
gi|110618224 CD1A antigen precursor [Homo sapiens]                     82   9e-16
gi|239740920 PREDICTED: similar to major histocompatibility comp...    75   9e-14
gi|239740918 PREDICTED: similar to major histocompatibility comp...    75   9e-14
gi|4504399 major histocompatibility complex, class II, DM beta p...    73   3e-13
gi|169168591 PREDICTED: similar to major histocompatibility comp...    72   7e-13
gi|24797076 major histocompatibility complex, class II, DP beta ...    70   2e-12
gi|4502649 CD1D antigen precursor [Homo sapiens]                       68   1e-11

>gi|149158698 major histocompatibility complex, class I, F isoform 2
           precursor [Homo sapiens]
          Length = 346

 Score =  717 bits (1850), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV 346
           PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV 346


>gi|149158702 major histocompatibility complex, class I, F isoform 1
           precursor [Homo sapiens]
          Length = 442

 Score =  715 bits (1846), Expect = 0.0
 Identities = 345/345 (100%), Positives = 345/345 (100%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
           PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345


>gi|24797067 major histocompatibility complex, class I, A precursor
           [Homo sapiens]
          Length = 365

 Score =  577 bits (1487), Expect = e-165
 Identities = 277/345 (80%), Positives = 302/345 (87%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPR+LLLLLSGALALT TWAGSHS+RYF T+VSRPGRGEPR+IAV YVDDTQF+RFDSD
Sbjct: 4   MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AA  RMEPR PW+EQEGP+YW+  T   KA +QTDRV L  L   YNQSEAGSHT+Q M 
Sbjct: 64  AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCD+G DGR LRGY Q AYDGKDYI+LNEDLRSWTAAD  AQIT+R +EA   AE+ R Y
Sbjct: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           L+G C+E LRRYLENGKETLQR DPPK H+ HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGE+QTQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
           PTIPIVGI+AGLV+LGAV+TGAVVAAVMWR+KSSDR  GSY+QAA
Sbjct: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAA 348


>gi|17986001 major histocompatibility complex, class I, B precursor
           [Homo sapiens]
          Length = 362

 Score =  567 bits (1461), Expect = e-162
 Identities = 275/345 (79%), Positives = 300/345 (86%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPR++LLLLS ALALT+TWAGSHS+RYF T+VSRPGRGEPR+I+V YVDDTQF+RFDSD
Sbjct: 4   MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AA PR EPR PW+EQEGP+YW+  T   KA AQTDR +LRNL   YNQSEAGSHTLQ M 
Sbjct: 64  AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCD+GPDGRLLRG+ Q+AYDGKDYI+LNEDLRSWTAADT AQITQR +EA   AE+ R Y
Sbjct: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LEGEC+E LRRYLENGK+ L+RADPPK HV HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGE+QTQDTELVETRPAGD TFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
            T+PIVGIVAGL VL  VV GAVVAAVM R+KSS    GSYSQAA
Sbjct: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAA 348


>gi|4504415 major histocompatibility complex, class I, G precursor
           [Homo sapiens]
          Length = 338

 Score =  553 bits (1426), Expect = e-158
 Identities = 265/335 (79%), Positives = 292/335 (87%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPR+L LLLSGAL LT+TWAGSHS+RYFS AVSRPGRGEPR+IA+ YVDDTQF+RFDSD
Sbjct: 4   MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           +A PRMEPR PWVEQEGP+YWE  T   KA+AQTDR+ L+ L   YNQSEA SHTLQ M 
Sbjct: 64  SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCD+G DGRLLRGY Q+AYDGKDY++LNEDLRSWTAADT AQI++R  EA   AE+ R Y
Sbjct: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LEG C+E L RYLENGKE LQRADPPK HV HHP+ D+EATLRCWALGFYPAEI LTWQR
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGE+QTQD ELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL+LRW+QS  
Sbjct: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSD 335
           PTIPI+GIVAGLVVL AVVTGA VAAV+WRKKSSD
Sbjct: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338


>gi|52630342 major histocompatibility complex, class I, C precursor
           [Homo sapiens]
          Length = 366

 Score =  549 bits (1415), Expect = e-156
 Identities = 270/346 (78%), Positives = 294/346 (84%), Gaps = 1/346 (0%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPR+LLLLLSG LALT+TWA SHS+RYF TAVSRPGRGEPR+I+V YVDDTQF+RFDSD
Sbjct: 4   MAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSD 63

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AA PR EPR PWVEQEGP+YW+  T   K  AQ DRV+LRNL   YNQSE GSHTLQ M+
Sbjct: 64  AASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMS 123

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCD+GPDGRLLRGY Q AYDGKDYI+LNEDLRSWTAADT AQITQR  EA   AE+ R Y
Sbjct: 124 GCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAY 183

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LEG C+E LRRYLENGKETLQRA+PPK HV HHP+SDHEATLRCWALGFYPAEITLTWQR
Sbjct: 184 LEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQR 243

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGE+QTQDTELVETRPAGDGTFQKWAAVVVP G+EQRYTCH+QHEGL +PL L WE S Q
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQ 303

Query: 301 PTIPIVGIVAGLVVLGAV-VTGAVVAAVMWRKKSSDRNRGSYSQAA 345
           PTIPI+GIVAGL VL  + V GAVV A+M R+KSS    GS SQAA
Sbjct: 304 PTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAA 349


>gi|62912479 major histocompatibility complex, class I, E precursor
           [Homo sapiens]
          Length = 358

 Score =  520 bits (1340), Expect = e-148
 Identities = 251/344 (72%), Positives = 284/344 (82%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           M   +LLLLLS ALALT TWAGSHSL+YF T+VSRPGRGEPR+I+V YVDDTQF+RFD+D
Sbjct: 1   MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AA PRM PR PW+EQEG +YW+  T  A+  AQ  RV LR L   YNQSEAGSHTLQ M+
Sbjct: 61  AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GC++GPDGR LRGY Q AYDGKDY++LNEDLRSWTA DT AQI+++       AE  R Y
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LE  C+E L +YLE GKETL   +PPK HV HHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240

Query: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
           DGE  TQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+P+ LRW+ + Q
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300

Query: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQA 344
           PTIPIVGI+AGLV+LG+VV+GAVVAAV+WRKKSS    GSYS+A
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKA 344


>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
           sapiens]
          Length = 366

 Score =  455 bits (1171), Expect = e-128
 Identities = 224/315 (71%), Positives = 251/315 (79%), Gaps = 4/315 (1%)

Query: 22  GSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYW 81
           GSHSLRYF TAVSRPG GEPR+I+V YVDDTQF+RFDSD+A PR EPR PW+EQEGP+YW
Sbjct: 38  GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97

Query: 82  EWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDG 141
           +  T   K  AQ+ RV L  L   YNQSEAGSHTLQ M GCD+GPDGR LRG+ Q AYDG
Sbjct: 98  DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157

Query: 142 KDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQ 201
           +DYI+LNEDLRSWTAADT AQIT+R  EA   AE  R YLEG C+E LRRYLE GK+ L 
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217

Query: 202 RADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGT 261
           RADPPKAHV HHPIS+ E TLRCWALGFYP EI+LTWQR+GE+QTQD ELVETRP+GDGT
Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277

Query: 262 FQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTG 321
           FQKWAA+VVP GEEQRYTC VQHEGL +PL LRWE  PQ +  I+GI+ GLV+L   V  
Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333

Query: 322 AVVAAVMWRKKSSDR 336
            V  AV+WRKK S R
Sbjct: 334 LVAGAVIWRKKRSGR 348


>gi|149158700 major histocompatibility complex, class I, F isoform 3
           precursor [Homo sapiens]
          Length = 254

 Score =  421 bits (1083), Expect = e-118
 Identities = 203/204 (99%), Positives = 204/204 (100%)

Query: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
           MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD
Sbjct: 1   MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60

Query: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
           AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN
Sbjct: 61  AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120

Query: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
           GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180

Query: 181 LEGECLELLRRYLENGKETLQRAD 204
           LEGECLELLRRYLENGKETLQRA+
Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204



 Score =  101 bits (251), Expect = 1e-21
 Identities = 52/53 (98%), Positives = 52/53 (98%)

Query: 294 RWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV 346
           R EQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV
Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV 254


>gi|4504417 major histocompatibility complex, class I-related [Homo
           sapiens]
          Length = 341

 Score =  222 bits (565), Expect = 4e-58
 Identities = 133/342 (38%), Positives = 192/342 (56%), Gaps = 17/342 (4%)

Query: 5   SLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
           + LL L   L +  + + +HSLRYF   VS P  G P +I+V YVD      +DS     
Sbjct: 6   AFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTR 63

Query: 65  RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
           + EPR PW+ E   P +WE  T   +   Q  +V L+ L R YN S  GSHT Q M GC+
Sbjct: 64  QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCE 121

Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLE 182
           +  DG    G+ Q+AYDG+D++  N+D  SW A D VA   ++ +EA ++   + + +LE
Sbjct: 122 LLEDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE 180

Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
            EC+  L+R+LE GK+TLQR +PP   V           L C A GFYP EI +TW ++G
Sbjct: 181 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG 240

Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ-- 300
           EE  Q+ +  +  P+GDGT+Q WA++ + P     Y+CHV+H G+   L     Q PQ  
Sbjct: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL-----QVPQES 295

Query: 301 PTIPIV-GIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
            TIP+V   V+G +VL  V+ G  V  ++WR++  ++N   Y
Sbjct: 296 ETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335


>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score =  202 bits (515), Expect = 3e-52
 Identities = 121/342 (35%), Positives = 180/342 (52%), Gaps = 9/342 (2%)

Query: 3   PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
           P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66

Query: 63  IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
             R+EPR PWV      Q W   +   K       V    ++  +N S+  SHTLQ + G
Sbjct: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123

Query: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
           C+M  D     GY ++ YDG+D++    D   W AA+  A  T+  +E  +  A + R Y
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LE +C   L++ LE G+  L +  PP   V HH ++    TLRC AL +YP  IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241

Query: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
           D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301

Query: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
             T+ ++G+++G+ V   ++   ++  ++ +++ S    G Y
Sbjct: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342


>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
          Length = 298

 Score =  191 bits (486), Expect = 6e-49
 Identities = 107/293 (36%), Positives = 156/293 (53%), Gaps = 6/293 (2%)

Query: 7   LLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRM 66
           LLLL G     +   G +SL Y  T +S+     P + A+  ++D QF R++S     + 
Sbjct: 11  LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KS 68

Query: 67  EPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP 126
           +P   W + EG + W+  +   KA        L++++  YN S  GSH LQG  GC++  
Sbjct: 69  QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126

Query: 127 DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE-YAEEFRTYLEGEC 185
           + R    + ++ YDGKDYI  N+++ +W   D  AQIT++ +EAE  Y +  + YLE EC
Sbjct: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186

Query: 186 LELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ 245
              LR+YL+  K  L R DPP   V  H     +  L+C A  FYP +I + W R GE Q
Sbjct: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ 246

Query: 246 TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQS 298
             +    +    G+GT+Q W  V VPP +   Y+CHVQH  L QPL++ WE S
Sbjct: 247 EPELR-GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298


>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
           sapiens]
          Length = 325

 Score =  189 bits (479), Expect = 4e-48
 Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%)

Query: 42  RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100
           R + + YVDD  F+ +D ++   R+EPR PWV      Q W   +   K       V   
Sbjct: 23  RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80

Query: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160
            ++  +N S+  SHTLQ + GC+M  D     GY ++ YDG+D++    D   W AA+  
Sbjct: 81  TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138

Query: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219
           A  T+  +E  +  A + R YLE +C   L++ LE G+  L +  PP   V HH ++   
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197

Query: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278
            TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257

Query: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338
           TC V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316

Query: 339 GSY 341
           G Y
Sbjct: 317 GHY 319


>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
           sapiens]
          Length = 334

 Score =  186 bits (471), Expect = 3e-47
 Identities = 116/342 (33%), Positives = 173/342 (50%), Gaps = 23/342 (6%)

Query: 3   PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
           P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66

Query: 63  IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
             R+EPR PWV      Q W   +   K       V    ++  +N S+  SHTLQ + G
Sbjct: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123

Query: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
           C+M  D     GY ++ YDG+D++    D   W AA+  A  T+  +E  +  A + R Y
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182

Query: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
           LE +C   L++ LE G+  L +                  TLRC AL +YP  IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227

Query: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
           D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287

Query: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
             T+ ++G+++G+ V   ++   ++  ++ +++ S    G Y
Sbjct: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328


>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
           sapiens]
          Length = 260

 Score =  166 bits (421), Expect = 2e-41
 Identities = 88/231 (38%), Positives = 134/231 (58%), Gaps = 5/231 (2%)

Query: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
           SHTLQ + GC+M  D     GY ++ YDG+D++    D   W AA+  A  T+  +E  +
Sbjct: 27  SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85

Query: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
             A + R YLE +C   L++ LE G+  L +  PP   V HH ++    TLRC AL +YP
Sbjct: 86  IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144

Query: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
             IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYTC V+H GL QP
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204

Query: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
           LI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    G Y
Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254


>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
           sapiens]
          Length = 246

 Score =  149 bits (377), Expect = 3e-36
 Identities = 83/231 (35%), Positives = 127/231 (54%), Gaps = 19/231 (8%)

Query: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
           SHTLQ + GC+M  D     GY ++ YDG+D++    D   W AA+  A  T+  +E  +
Sbjct: 27  SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85

Query: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
             A + R YLE +C   L++ LE G+  L +                  TLRC AL +YP
Sbjct: 86  IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130

Query: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
             IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYTC V+H GL QP
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190

Query: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
           LI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    G Y
Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240


>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
           sapiens]
          Length = 365

 Score =  140 bits (354), Expect = 1e-33
 Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)

Query: 6   LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
           LL LL G+L      A SH SL Y  TAVS P  G P +    ++   Q+L ++S     
Sbjct: 14  LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66

Query: 65  RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
             EP   WV E +   YWE  T   +   +    A + L         G +TLQG+ GC+
Sbjct: 67  EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120

Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
           +GPD   +    + A +G+++++ +    +W      A  I+QR+ + ++ A +  T+L 
Sbjct: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179

Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
             C   LR +LE G+  L+  +PP   +   P S   + L C A  FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239

Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
                 T   +  P  DG+F   +++ V  G+E  Y C VQH GL QPL +  E   + +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297

Query: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
           + +VGIV G+++L A   G    A++WR+  S
Sbjct: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326


>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
           sapiens]
          Length = 365

 Score =  140 bits (354), Expect = 1e-33
 Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)

Query: 6   LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
           LL LL G+L      A SH SL Y  TAVS P  G P +    ++   Q+L ++S     
Sbjct: 14  LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66

Query: 65  RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
             EP   WV E +   YWE  T   +   +    A + L         G +TLQG+ GC+
Sbjct: 67  EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120

Query: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
           +GPD   +    + A +G+++++ +    +W      A  I+QR+ + ++ A +  T+L 
Sbjct: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179

Query: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
             C   LR +LE G+  L+  +PP   +   P S   + L C A  FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239

Query: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
                 T   +  P  DG+F   +++ V  G+E  Y C VQH GL QPL +  E   + +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297

Query: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
           + +VGIV G+++L A   G    A++WR+  S
Sbjct: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326


>gi|4557751 MHC class I polypeptide-related sequence A [Homo
           sapiens]
          Length = 383

 Score =  140 bits (352), Expect = 2e-33
 Identities = 94/293 (32%), Positives = 150/293 (51%), Gaps = 22/293 (7%)

Query: 6   LLLLLSGALALTDTWAGS--HSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAI 63
           + LLL+G        A +  HSLRY  T +S  G  +  ++   ++D   FLR D     
Sbjct: 6   VFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC- 64

Query: 64  PRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGC 122
            R +P+  W E   G + W+  T     N +  R+ L ++       + G H+LQ +  C
Sbjct: 65  -RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHI----KDQKEGLHSLQEIRVC 119

Query: 123 DMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEF 177
           ++  D       H + YDG+ ++S N + + WT      A T+A   + F +  E A + 
Sbjct: 120 EIHEDNSTRSSQHFY-YDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLK--EDAMKT 176

Query: 178 RTY---LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEI 234
           +T+   +  +CL+ LRRYL++G   L+R  PP  +V     S+   T+ C A GFYP  I
Sbjct: 177 KTHYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNI 235

Query: 235 TLTWQRDGEEQTQDT-ELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
           TL+W++DG   + DT +  +  P G+GT+Q W A  +  GEEQR+TC+++H G
Sbjct: 236 TLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288


>gi|167857788 MHC class I polypeptide-related sequence B [Homo
           sapiens]
          Length = 383

 Score =  137 bits (345), Expect = 1e-32
 Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 20/276 (7%)

Query: 21  AGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQ 79
           A  HSLRY    +S+ G  +  ++A  ++D   FLR+D      R +P+  W E   G +
Sbjct: 23  AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAK 80

Query: 80  YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAY 139
            W+  T     N Q     LR  L      + G H+LQ +  C++  D    RG     Y
Sbjct: 81  TWDTETEDLTENGQD----LRRTLTHIKDQKGGLHSLQEIRVCEIHEDSST-RGSRHFYY 135

Query: 140 DGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEFRTY---LEGECLELLRR 191
           DG+ ++S N + +  T      A T+A     F++  E A + +T+   ++ +CL+ L+R
Sbjct: 136 DGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK--EDAMKTKTHYRAMQADCLQKLQR 193

Query: 192 YLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDT-E 250
           YL++G   ++R  PP  +V    +S+   T+ C A  FYP  ITLTW++DG   + +T +
Sbjct: 194 YLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQ 252

Query: 251 LVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
             +  P G+GT+Q W A  +  GEEQR+TC+++H G
Sbjct: 253 WGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288


>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
           sapiens]
          Length = 168

 Score =  116 bits (291), Expect = 3e-26
 Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)

Query: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
           PP   V HH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85

Query: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
            W  + VPPGEEQRYTC V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   +
Sbjct: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144

Query: 324 VAAVMWRKKSSDRNRGSY 341
           +  ++ +++ S    G Y
Sbjct: 145 LFIILRKRQGSRGAMGHY 162


>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
           sapiens]
          Length = 256

 Score =  116 bits (291), Expect = 3e-26
 Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)

Query: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
           PP   V HH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173

Query: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
            W  + VPPGEEQRYTC V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   +
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232

Query: 324 VAAVMWRKKSSDRNRGSY 341
           +  ++ +++ S    G Y
Sbjct: 233 LFIILRKRQGSRGAMGHY 250



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 3  PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
          P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 7  PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66

Query: 63 IPRMEPREPWVEQE-GPQYW 81
            R+EPR PWV      Q W
Sbjct: 67 --RVEPRTPWVSSRISSQMW 84


>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
           sapiens]
          Length = 242

 Score =  108 bits (271), Expect = 5e-24
 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%)

Query: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175

Query: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339
           C V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    G
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234

Query: 340 SY 341
            Y
Sbjct: 235 HY 236



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 3   PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
           P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66

Query: 63  IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
             R+EPR PWV      Q W   +   K       V    ++  +N S+  +   + +N
Sbjct: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123


>gi|110618224 CD1A antigen precursor [Homo sapiens]
          Length = 327

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 56/206 (27%), Positives = 93/206 (45%), Gaps = 10/206 (4%)

Query: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEA----E 171
           +Q   GC++   G++   + Q AY G D++S   +  SW        + + F +     +
Sbjct: 113 IQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169

Query: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
              +     L   C   +   L+ GK  LQR   P+A ++H P        L C   GFY
Sbjct: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229

Query: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
           P  + + W R GE++ Q T+  +  P+ DGT+   A + V  GE    +C V+H  L  Q
Sbjct: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288

Query: 290 PLILRWEQSPQPTIPIVGIVAGLVVL 315
            ++L WE        I+ ++  L++L
Sbjct: 289 DIVLYWEHHSSVGFIILAVIVPLLLL 314


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 11/194 (5%)

Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
           +RG  ++ Y+ ++Y   + D+  + A   +      ++ ++ E  E  R  L+  C    
Sbjct: 56  VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRH-- 113

Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
             Y    + TLQR   P   ++       +H   L C    FYPA+I + W R+ +E+T 
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172

Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
                     GD TFQ    + + P     YTCHV+H  L  P+I+ W    +S Q  + 
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232

Query: 304 -PIVGIVAGLVVLG 316
             I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 11/194 (5%)

Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
           +RG  ++ Y+ ++Y   + D+  + A   +      ++ ++ E  E  R  L+  C    
Sbjct: 56  VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRH-- 113

Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
             Y    + TLQR   P   ++       +H   L C    FYPA+I + W R+ +E+T 
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172

Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
                     GD TFQ    + + P     YTCHV+H  L  P+I+ W    +S Q  + 
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232

Query: 304 -PIVGIVAGLVVLG 316
             I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246


>gi|4504399 major histocompatibility complex, class II, DM beta
           precursor [Homo sapiens]
          Length = 263

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 44/135 (32%), Positives = 71/135 (52%), Gaps = 8/135 (5%)

Query: 202 RADPPKAHVAHH-PISDHEAT-LRCWALGFYPAEITLTWQRDGEEQTQDTELVET-RPAG 258
           R  PP   VA   P +  E   L C+  GFYPAE+T+TW+++G+     +   +T +P G
Sbjct: 111 RTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNG 170

Query: 259 DGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ--SPQPTIPIVGIVAGLVVLG 316
           D T+Q  + + + P     YTC V+H G P+P++  W    SP  T+  V + A  + LG
Sbjct: 171 DWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLK-VSVSAVTLGLG 229

Query: 317 AVVTGAVVAAVMWRK 331
            ++    +  + WR+
Sbjct: 230 LIIFS--LGVISWRR 242


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 11/194 (5%)

Query: 131 LRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELL 189
           +RG  ++ Y+ ++Y   + D+  + A   +      ++ ++ E  E  R  ++  C    
Sbjct: 56  VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRH-- 113

Query: 190 RRYLENGKETLQRADPPKAHVAHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
             Y    + TLQR   P   ++       +H   L C    FYPA+I + W R+ +E+T 
Sbjct: 114 -NYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETA 172

Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRW---EQSPQPTI- 303
                     GD TFQ    + + P     YTCHV+H  L  P+ + W    +S Q  + 
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKML 232

Query: 304 -PIVGIVAGLVVLG 316
             I G V GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 52/213 (24%), Positives = 89/213 (41%), Gaps = 11/213 (5%)

Query: 132 RGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAE-EYAEEFRTYLEGECLELLR 190
           R   ++ Y+ +++   + D+  + A   + +    ++ ++ +  EE R   +  C     
Sbjct: 52  RFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRH--- 108

Query: 191 RYLENGKETLQRADPPKAHVAHH---PISDHEATLRCWALGFYPAEITLTWQRDGEEQTQ 247
            Y   G  TLQR   P+ +V+     P+  H   L C    FYP  I + W  +G+E+T 
Sbjct: 109 NYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNL-LVCHVTDFYPGSIQVRWFLNGQEETA 167

Query: 248 DTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVG 307
                     GD TFQ    + + P +   YTC V+H  L  P+ + W+           
Sbjct: 168 GVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTL 227

Query: 308 IVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGS 340
             AG  VLG ++ G     +   ++S    RGS
Sbjct: 228 TGAGGFVLGLIICG---VGIFMHRRSKKVQRGS 257


>gi|4502649 CD1D antigen precursor [Homo sapiens]
          Length = 335

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)

Query: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADT----VAQITQRFYEAE 171
           LQ   GC++ P G     +   A+ GKD +S      SW         V    Q   + +
Sbjct: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170

Query: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
              E  +  L G C + +   LE+GK  L++   PKA ++  P        L C   GFY
Sbjct: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230

Query: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
           P  + + W R GE++ Q T+  +  P  D T+   A + V  GE    +C V+H  L  Q
Sbjct: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289

Query: 290 PLILRW 295
            ++L W
Sbjct: 290 DIVLYW 295


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,833,128
Number of Sequences: 37866
Number of extensions: 723677
Number of successful extensions: 1992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1772
Number of HSP's gapped (non-prelim): 165
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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