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Search of human proteins with 144953898
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 1084 0.0
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 978 0.0
gi|118918415 shank-interacting protein-like 1 [Homo sapiens] 156 4e-38
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 70 5e-12
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 70 5e-12
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 69 8e-12
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 69 1e-11
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 68 2e-11
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 68 2e-11
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 68 2e-11
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 68 2e-11
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 68 2e-11
gi|22749145 ring finger protein 217 [Homo sapiens] 67 4e-11
gi|50284696 IBR domain containing 2 [Homo sapiens] 66 7e-11
gi|38045938 ring finger protein 144 [Homo sapiens] 66 9e-11
gi|109150431 ring finger protein 31 [Homo sapiens] 56 9e-08
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 55 1e-07
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 54 3e-07
gi|5453557 ariadne homolog 2 [Homo sapiens] 54 3e-07
gi|35493801 ring finger protein 19 [Homo sapiens] 54 4e-07
gi|35493782 ring finger protein 19 [Homo sapiens] 54 4e-07
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 52 1e-06
gi|169790973 parkin isoform 3 [Homo sapiens] 48 2e-05
gi|169790971 parkin isoform 2 [Homo sapiens] 48 2e-05
gi|169790969 parkin isoform 1 [Homo sapiens] 48 2e-05
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 42 0.001
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 42 0.002
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 41 0.002
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 41 0.002
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens] 41 0.002
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 1084 bits (2803), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVS 60
MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVS
Sbjct: 1 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVS 60
Query: 61 VEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVR 120
VEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVR
Sbjct: 61 VEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVR 120
Query: 121 QNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQE 180
QNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQE
Sbjct: 121 QNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQE 180
Query: 181 PGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARL 240
PGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARL
Sbjct: 181 PGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARL 240
Query: 241 AGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC 300
AGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC
Sbjct: 241 AGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC 300
Query: 301 LHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISI 360
LHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISI
Sbjct: 301 LHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISI 360
Query: 361 AENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLAL 420
AENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLAL
Sbjct: 361 AENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLAL 420
Query: 421 RAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPR 480
RAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPR
Sbjct: 421 RAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPR 480
Query: 481 WGPGGPGDTSGGCRCRVNGIPCHPSCQNCH 510
WGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
Sbjct: 481 WGPGGPGDTSGGCRCRVNGIPCHPSCQNCH 510
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 978 bits (2529), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 56 RLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLH 115
RLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLH
Sbjct: 14 RLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLH 73
Query: 116 SHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKP 175
SHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKP
Sbjct: 74 SHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKP 133
Query: 176 GVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEE 235
GVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEE
Sbjct: 134 GVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEE 193
Query: 236 ERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAV 295
ERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAV
Sbjct: 194 ERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAV 253
Query: 296 VLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLD 355
VLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLD
Sbjct: 254 VLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLD 313
Query: 356 LGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ 415
LGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ
Sbjct: 314 LGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ 373
Query: 416 EDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV 475
EDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV
Sbjct: 374 EDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV 433
Query: 476 TKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH 510
TKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
Sbjct: 434 TKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH 468
>gi|118918415 shank-interacting protein-like 1 [Homo sapiens]
Length = 387
Score = 156 bits (395), Expect = 4e-38
Identities = 100/224 (44%), Positives = 127/224 (56%), Gaps = 31/224 (13%)
Query: 9 EEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVSVEDAQM-- 66
EE+A SL RA+AGGDE+ A + A LA+ RV LSVQL+ P IRL V++EDA
Sbjct: 173 EELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAA 232
Query: 67 ---HTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNG 123
+ + L V P TVA+L++ VF + GFPP +Q+WVIG+ L + +L S+GVRQ+G
Sbjct: 233 SAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDG 292
Query: 124 DSAYLYLLSARN----TSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQ 179
D A+LYLLSA T +PQ Q +M +LG PP G+P
Sbjct: 293 DPAFLYLLSAPREAPATGPSPQHPQ-----KMDGELG------------RLFPPSLGLPP 335
Query: 180 EPGRGQPDA--VPEPPPVGWQCPGCTFINKPTRPGCEMCCRARP 221
P QP A +P P W CP CTFIN P RPGCEMC RP
Sbjct: 336 GP---QPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRP 376
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 70.1 bits (170), Expect = 5e-12
Identities = 71/299 (23%), Positives = 121/299 (40%), Gaps = 62/299 (20%)
Query: 235 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 293
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 467 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 525
Query: 294 AVVLRECLHTFCRECLQGTIRNSQEA-------EVSCPFIDNTYSCSGKLLEREIKALLT 346
+ H FC+ECL IR +QEA E+SC T S LE+ + +
Sbjct: 526 ELTQCADAHLFCKECL---IRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTIL 582
Query: 347 PEDYQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLL 401
+ Y+R AE A +Y + P C + DV F+C P C C
Sbjct: 583 YKYYERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRK 635
Query: 402 CKAI---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKD 458
C+ + H + C+E E ++ + + + T ++ +C +C + K +
Sbjct: 636 CQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSE 686
Query: 459 GCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 509
GC+ + C C ++C++ CR +NG C HP CQ C
Sbjct: 687 GCNRMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 727
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 70.1 bits (170), Expect = 5e-12
Identities = 71/299 (23%), Positives = 121/299 (40%), Gaps = 62/299 (20%)
Query: 235 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 293
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 524 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 582
Query: 294 AVVLRECLHTFCRECLQGTIRNSQEA-------EVSCPFIDNTYSCSGKLLEREIKALLT 346
+ H FC+ECL IR +QEA E+SC T S LE+ + +
Sbjct: 583 ELTQCADAHLFCKECL---IRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTIL 639
Query: 347 PEDYQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLL 401
+ Y+R AE A +Y + P C + DV F+C P C C
Sbjct: 640 YKYYERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRK 692
Query: 402 CKAI---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKD 458
C+ + H + C+E E ++ + + + T ++ +C +C + K +
Sbjct: 693 CQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSE 743
Query: 459 GCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 509
GC+ + C C ++C++ CR +NG C HP CQ C
Sbjct: 744 GCNRMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 784
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 69.3 bits (168), Expect = 8e-12
Identities = 85/333 (25%), Positives = 111/333 (33%), Gaps = 96/333 (28%)
Query: 169 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 228
EP PP P P P A PPP P P E A EA A
Sbjct: 55 EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
Query: 229 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 288
D+EE A G E ECP+C
Sbjct: 98 EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
Query: 289 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 345
L P A L C H CR+CL+ +R + +SCP CS +L +I+ LL
Sbjct: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
Query: 346 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 398
Y+ F+ Y PDC+ WC D V + C C +
Sbjct: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
Query: 399 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEA--- 444
C CK I H C ++ RAQ + T L + G A
Sbjct: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPADDI 284
Query: 445 MRCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 475
CP+C +++ DG C+ + C VC E CW+
Sbjct: 285 KPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 317
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 68.9 bits (167), Expect = 1e-11
Identities = 84/332 (25%), Positives = 111/332 (33%), Gaps = 95/332 (28%)
Query: 169 EPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPA 228
EP PP P P P A PPP P P E A EA A
Sbjct: 55 EPPPPAAQPPPAPA---PAAAQGPPPEAL----------PAEPAAE----AEAEAAAAAA 97
Query: 229 SYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSV 288
D+EE A G E ECP+C
Sbjct: 98 EPGFDDEEAAEGGGP--------------------------------GAEEVECPLCLVR 125
Query: 289 LAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLLEREIKALL 345
L P A L C H CR+CL+ +R + +SCP CS +L +I+ LL
Sbjct: 126 LPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCP------ECSERLNPHDIRLLL 179
Query: 346 TP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFTCPVCFHVN 398
Y+ F+ Y PDC+ WC D V + C C +
Sbjct: 180 ADPPLMHKYEEFM-----------LRRYLASDPDCR-WCPAPDCGYAVIAYGCASCPKLT 227
Query: 399 ----------CLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQG--EAM 445
C CK I H C ++ RAQ + T L + G +
Sbjct: 228 CEREGCQTEFCYHCKQIWHPNQTCDMARQQ---RAQTLRVRTKHTSGLSYGQESGPDDIK 284
Query: 446 RCPQCQ-IVVQKKDG-CDWIRCTVCHTEICWV 475
CP+C +++ DG C+ + C VC E CW+
Sbjct: 285 PCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWL 316
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)
Query: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325
Q+ N++ C +C+ E + EC H +C+ CL+ IR+ Q ++CP
Sbjct: 208 QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 266
Query: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385
C ++K L+ E + R+ L + + + A +C P C+ E
Sbjct: 267 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 323
Query: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434
C C C LC+ + ++ CK E L LR Q D A ++ + +
Sbjct: 324 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 383
Query: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
++ L++ E+ CP C ++K DGC+ + CT C CW+ G
Sbjct: 384 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)
Query: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325
Q+ N++ C +C+ E + EC H +C+ CL+ IR+ Q ++CP
Sbjct: 208 QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 266
Query: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385
C ++K L+ E + R+ L + + + A +C P C+ E
Sbjct: 267 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 323
Query: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434
C C C LC+ + ++ CK E L LR Q D A ++ + +
Sbjct: 324 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 383
Query: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
++ L++ E+ CP C ++K DGC+ + CT C CW+ G
Sbjct: 384 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)
Query: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325
Q+ N++ C +C+ E + EC H +C+ CL+ IR+ Q ++CP
Sbjct: 208 QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 266
Query: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385
C ++K L+ E + R+ L + + + A +C P C+ E
Sbjct: 267 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 323
Query: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434
C C C LC+ + ++ CK E L LR Q D A ++ + +
Sbjct: 324 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 383
Query: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
++ L++ E+ CP C ++K DGC+ + CT C CW+ G
Sbjct: 384 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)
Query: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325
Q+ N++ C +C+ E + EC H +C+ CL+ IR+ Q ++CP
Sbjct: 82 QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 140
Query: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385
C ++K L+ E + R+ L + + + A +C P C+ E
Sbjct: 141 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 197
Query: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434
C C C LC+ + ++ CK E L LR Q D A ++ + +
Sbjct: 198 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 257
Query: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
++ L++ E+ CP C ++K DGC+ + CT C CW+ G
Sbjct: 258 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 309
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/232 (24%), Positives = 96/232 (41%), Gaps = 27/232 (11%)
Query: 270 QRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPF 325
Q+ N++ C +C+ E + EC H +C+ CL+ IR+ Q ++CP
Sbjct: 208 QQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCP- 266
Query: 326 IDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD 385
C ++K L+ E + R+ L + + + A +C P C+ E
Sbjct: 267 ---EPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPG 323
Query: 386 VNEFTCPVCFHVNCLLCKAIHEQMN-CKEYQEDLA-LR---AQNDVAARQTTE------M 434
C C C LC+ + ++ CK E L LR Q D A ++ + +
Sbjct: 324 CTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRV 383
Query: 435 LKVMLQQGEAMR--------CPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
++ L++ E+ CP C ++K DGC+ + CT C CW+ G
Sbjct: 384 IQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 67.0 bits (162), Expect = 4e-11
Identities = 48/172 (27%), Positives = 76/172 (44%), Gaps = 35/172 (20%)
Query: 318 EAEVSCPFIDNTYSCSGKLLEREIKALLTPED---YQRFLDLGISIAENRSAFSYHCKTP 374
+ E+ CP + C L E + LT ED Y+ FL+LG + + P
Sbjct: 7 QVEIKCPITE----CFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTKPC-------P 55
Query: 375 DCKGWCFFE-----------DDVNEFTCPVCFHVNCLLCKAI-HEQMNCKEYQEDLALRA 422
CK + F+ + + CP C V C C + HE +NCKEY++
Sbjct: 56 QCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHEGVNCKEYKK------ 109
Query: 423 QNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 474
D R ++ Q A +CP+C+I +Q+ +GCD + C+ C+T C+
Sbjct: 110 -GDKLLRHWAS--EIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCY 158
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 66.2 bits (160), Expect = 7e-11
Identities = 48/202 (23%), Positives = 79/202 (39%), Gaps = 20/202 (9%)
Query: 282 CPVCYSVLAPGEAVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLL 337
C +C + + L+EC FC CL Q IR + ++CP D G L
Sbjct: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP--DMVCLNHGTLQ 87
Query: 338 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWC-FFEDDVNE---FTCPV 393
E EI L+ + +Q + L + + C DC+ C D + CP
Sbjct: 88 EAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
Query: 394 CFHVNCLLCK-AIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 452
C C CK A H +++C++ Q + + +K +CP C++
Sbjct: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIK---------QCPVCRV 198
Query: 453 VVQKKDGCDWIRCTVCHTEICW 474
+++ +GC + C C CW
Sbjct: 199 YIERNEGCAQMMCKNCKHTFCW 220
Score = 30.4 bits (67), Expect = 4.0
Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 281 ECPVCYSVLAPGEA---VVLRECLHTFCRECLQ 310
+CPVC + E ++ + C HTFC CLQ
Sbjct: 192 QCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQ 224
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 65.9 bits (159), Expect = 9e-11
Identities = 48/202 (23%), Positives = 71/202 (35%), Gaps = 18/202 (8%)
Query: 282 CPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSGKLL 337
C +C + + +C FC CL+ I+ E +SCP D G L
Sbjct: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCP--DAACPKQGHLQ 77
Query: 338 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED----DVNEFTCPV 393
E EI+ ++ E QR+ L C C+ C +D C
Sbjct: 78 ENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA 137
Query: 394 CFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 452
C C CKA H C E L + A K+ RCP+C++
Sbjct: 138 CRMEFCSTCKASWHPGQGCPETMPITFLPGETSAA-------FKMEEDDAPIKRCPKCKV 190
Query: 453 VVQKKDGCDWIRCTVCHTEICW 474
+++ +GC + C C CW
Sbjct: 191 YIERDEGCAQMMCKNCKHAFCW 212
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 55.8 bits (133), Expect = 9e-08
Identities = 57/250 (22%), Positives = 99/250 (39%), Gaps = 31/250 (12%)
Query: 244 EEALRQYQQRKQQQQEGNYLQHVQLDQ-RSLVLNTEPAECPVCYSVLAPGEAVVLRECLH 302
E AL Q+ + + G+ ++ V+ Q R+ + EC VC L L C
Sbjct: 660 ELALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCEC 719
Query: 303 TFCRECLQG----TIRNSQEAEVSCP------FIDNTYSCSG-KLLEREIKALLTPEDYQ 351
T C +C + ++ ++ CP D+T S L+ +++ L P+ Y
Sbjct: 720 TICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYA 779
Query: 352 RF---LDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCK----A 404
F L G+ + + + + C +E + E TCP C C+ CK
Sbjct: 780 LFHKKLTEGVLMRDPKFLWCAQCSFG-----FIYEREQLEATCPQCHQTFCVRCKRQWEE 834
Query: 405 IHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI-VVQKKDGCDWI 463
H +C+++Q + ND + L + LQ+ + CP+C+ + GC
Sbjct: 835 QHRGRSCEDFQN---WKRMND--PEYQAQGLAMYLQE-NGIDCPKCKFSYALARGGCMHF 888
Query: 464 RCTVCHTEIC 473
CT C + C
Sbjct: 889 HCTQCRHQFC 898
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/211 (21%), Positives = 77/211 (36%), Gaps = 29/211 (13%)
Query: 279 PAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSG 334
P CPVC S L + + C+H C+ C L I + +CP D +G
Sbjct: 2067 PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTG 2126
Query: 335 KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVC 394
+ + + Y++ L G E+ S ++ C + TC C
Sbjct: 2127 AFIRAIVSSPEVISKYEKALLRGY--VESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKC 2184
Query: 395 FHVNCLLCK--AIHEQMNCKE---------YQEDLALRAQNDVAARQTTEMLKVMLQQGE 443
+C C H +C Y + +++ AQ+ A+ ++
Sbjct: 2185 GWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISK---------- 2234
Query: 444 AMRCPQCQIVVQKKDGCDWIRCTVCHTEICW 474
RCP CQ ++K +GC + C C+ CW
Sbjct: 2235 --RCPSCQAPIEKNEGCLHMTCAKCNHGFCW 2263
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 54.3 bits (129), Expect = 3e-07
Identities = 51/220 (23%), Positives = 87/220 (39%), Gaps = 31/220 (14%)
Query: 282 CPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSGKLL 337
C +C ++ E V C H FCR C L I+ + + CP Y C +
Sbjct: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCP----AYDCFQLVP 388
Query: 338 EREIKALLTPEDYQRFLDLGI-SIAENRSAFSYHCKTPDC--------KGWCFFEDDVNE 388
I+++++ E +R+L I + EN A + C TP C +G D
Sbjct: 389 VDIIESVVSKEMDKRYLQFDIKAFVENNPAIKW-CPTPGCDRAVRLTKQGSNTSGSDTLS 447
Query: 389 FTCPVCFHVNC----LLC----KAIHEQMNCKEY----QEDLALRAQNDVAARQTTE-ML 435
F V+C L C HE +C+ + Q+ ++ + V + E
Sbjct: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507
Query: 436 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV 475
+ + C C+ +QK +GC+ ++C C + CW+
Sbjct: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWI 547
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 27/210 (12%)
Query: 279 PAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSG 334
P C VC + E ++ C H FCR C + +++ VSC D C
Sbjct: 136 PHHCAVCMQFVRK-ENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQD----CPL 190
Query: 335 KLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD-VNEF 389
+ E + LL E+ Y+R+L + + C DC ++
Sbjct: 191 RTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQL---CPGADCPMVIRVQEPRARRV 247
Query: 390 TCPVCFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCP 448
C C V C C+ + H +C ++ L A + A + K CP
Sbjct: 248 QCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTK---------DCP 298
Query: 449 QCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
+C I ++K GC+ ++C+ C + CW+ G
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 53.5 bits (127), Expect = 4e-07
Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 48/222 (21%)
Query: 281 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLL 337
ECP+C + + C H C +CL+ +R + +SCP C+ +
Sbjct: 131 ECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP------ECTERFN 184
Query: 338 EREIKALLTP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFT 390
+I+ +L+ E Y+ F+ +A+ PDC+ WC D V F
Sbjct: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVAD-----------PDCR-WCPAPDCGYAVIAFG 232
Query: 391 CPVCFHVNC----------LLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML 439
C C + C CK I H C +++ RAQ+ + +
Sbjct: 233 CASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQE---RAQSLRLRTIRSSSISYSQ 289
Query: 440 QQGEAMR----CPQCQI-VVQKKDG-CDWIRCTVCHTEICWV 475
+ G A CP+C +++ DG C+ + C VC E CW+
Sbjct: 290 ESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWL 331
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 53.5 bits (127), Expect = 4e-07
Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 48/222 (21%)
Query: 281 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLL 337
ECP+C + + C H C +CL+ +R + +SCP C+ +
Sbjct: 131 ECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP------ECTERFN 184
Query: 338 EREIKALLTP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFT 390
+I+ +L+ E Y+ F+ +A+ PDC+ WC D V F
Sbjct: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVAD-----------PDCR-WCPAPDCGYAVIAFG 232
Query: 391 CPVCFHVNC----------LLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML 439
C C + C CK I H C +++ RAQ+ + +
Sbjct: 233 CASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQE---RAQSLRLRTIRSSSISYSQ 289
Query: 440 QQGEAMR----CPQCQI-VVQKKDG-CDWIRCTVCHTEICWV 475
+ G A CP+C +++ DG C+ + C VC E CW+
Sbjct: 290 ESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWL 331
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/232 (23%), Positives = 91/232 (39%), Gaps = 35/232 (15%)
Query: 267 QLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAE-----V 321
Q++ RS + + C +CY + P EC H FC +C + E +
Sbjct: 174 QMNTRS---SAQDMPCQICY-LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTI 229
Query: 322 SCPFIDNTYSCSGKLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCK 377
SCP + C + + + L+T YQ + S E + C PDC
Sbjct: 230 SCP----AHGCDILVDDNTVMRLITDSKVKLKYQHLITN--SFVECNRLLKW-CPAPDCH 282
Query: 378 GWCFFE-DDVNEFTCPVCFHVNCLLC-KAIHEQMNCKEYQEDLALRAQNDVAARQTTEML 435
+ D C C C C + H+ + CK ++ + + +D +T+ +
Sbjct: 283 HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIK-KCDDD---SETSNWI 337
Query: 436 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGG 485
++ CP+C + ++K GC+ + C C E CWV GP W P G
Sbjct: 338 AANTKE-----CPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGP-WEPHG 383
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/237 (23%), Positives = 79/237 (33%), Gaps = 26/237 (10%)
Query: 273 LVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCREC--LQGTIRNSQEAEVSCPFIDN 328
+ N+ C C V +P V++ +C H C +C L R + V P +
Sbjct: 80 IATNSRNITCITCTDVRSP---VLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGY 136
Query: 329 TYSCSGKLLEREIKAL-----LTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFE 383
+ C IK L L E Y R+ G + C P C E
Sbjct: 137 SLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMG-GVLCPRPGCGAGLLPE 195
Query: 384 DDVNEFTCPV-----CFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVM 438
D + TC C C CK + + C E Q + E +
Sbjct: 196 PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWE 255
Query: 439 LQQGEAMR-----CPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGGPGD 488
E ++ CP+C + V+K GC ++C C E CW G W GD
Sbjct: 256 AASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCW-NCGCEWNRVCMGD 311
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/237 (23%), Positives = 79/237 (33%), Gaps = 26/237 (10%)
Query: 273 LVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCREC--LQGTIRNSQEAEVSCPFIDN 328
+ N+ C C V +P V++ +C H C +C L R + V P +
Sbjct: 201 IATNSRNITCITCTDVRSP---VLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGY 257
Query: 329 TYSCSGKLLEREIKAL-----LTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFE 383
+ C IK L L E Y R+ G + C P C E
Sbjct: 258 SLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMG-GVLCPRPGCGAGLLPE 316
Query: 384 DDVNEFTCPV-----CFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVM 438
D + TC C C CK + + C E Q + E +
Sbjct: 317 PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWE 376
Query: 439 LQQGEAMR-----CPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGGPGD 488
E ++ CP+C + V+K GC ++C C E CW G W GD
Sbjct: 377 AASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCW-NCGCEWNRVCMGD 432
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/237 (23%), Positives = 79/237 (33%), Gaps = 26/237 (10%)
Query: 273 LVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCREC--LQGTIRNSQEAEVSCPFIDN 328
+ N+ C C V +P V++ +C H C +C L R + V P +
Sbjct: 229 IATNSRNITCITCTDVRSP---VLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGY 285
Query: 329 TYSCSGKLLEREIKAL-----LTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFE 383
+ C IK L L E Y R+ G + C P C E
Sbjct: 286 SLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMG-GVLCPRPGCGAGLLPE 344
Query: 384 DDVNEFTCPV-----CFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVM 438
D + TC C C CK + + C E Q + E +
Sbjct: 345 PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWE 404
Query: 439 LQQGEAMR-----CPQCQIVVQKKDGCDWIRC--TVCHTEICWVTKGPRWGPGGPGD 488
E ++ CP+C + V+K GC ++C C E CW G W GD
Sbjct: 405 AASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCW-NCGCEWNRVCMGD 460
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/160 (28%), Positives = 68/160 (42%), Gaps = 24/160 (15%)
Query: 132 SARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPE 191
+AR +L P+EL+ E ++ +G +D L P G P+ PG G P P
Sbjct: 84 AARLGALRPEELE-ELAGGLVRAVGLRDRPLSAENP-------GGEPEAPGEGGPAPEPR 135
Query: 192 PPPVGWQCPGC-TFINKP-TRP-GCEMCCR------ARPEAYQVPASYQ-------PDEE 235
P CP C ++KP T P G +C R ARP+ +V P E
Sbjct: 136 APRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAEC 195
Query: 236 ERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVL 275
RLAG+ +L++ QQ + + + D SL+L
Sbjct: 196 RLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLL 235
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/170 (24%), Positives = 62/170 (36%), Gaps = 30/170 (17%)
Query: 118 GVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEP-----GP 172
G Q D++ ++ RN RE L+M + L PR PL+P G
Sbjct: 973 GAAQRSDNSLIHATLRRNN--------REATLKMAQ------LADSPRAPLQPLAKSKGG 1018
Query: 173 PKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASY-- 230
P V Q P R PPP + C C+ ++PG + A +SY
Sbjct: 1019 PGGVVTQLPAR--------PPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSL 1070
Query: 231 -QPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEP 279
P + R R A + + Q Q L+H L + ++ L P
Sbjct: 1071 LSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPP 1120
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 18/115 (15%)
Query: 153 EDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQ---PDAVPEPPPVGWQCPGCTFINKPT 209
++ G K L QP+ PL P PP P PQ P + P +P PV P KP+
Sbjct: 545 QEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPP------KPS 598
Query: 210 RPGCEMCCRARPEAYQVPASYQPDEE---------ERARLAGEEEALRQYQQRKQ 255
G A P A PAS D+E + + EE L+ Q++K+
Sbjct: 599 SQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKK 653
>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
Length = 350
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 172 PPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQ 231
PP P V P A+ P G + P +++ PGC +RP + S
Sbjct: 24 PPPPPV-------SPPALTPAPAAGEEGPAP--LSETGAPGCS---GSRPPELEPERSLG 71
Query: 232 PDEEERARLAGEEEALRQYQQ-RKQQQQEGNYLQHVQL----------DQRSLVLN---- 276
R R E+E L + ++ +++++E + H L D+ ++N
Sbjct: 72 ---RFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSEL 128
Query: 277 TEPAECPVCYSVLAPGEAVVLRECLHTFCRECL 309
T C +C L +A + ECLHTFC+ C+
Sbjct: 129 TPYILCSICKGYLI--DATTITECLHTFCKSCI 159
>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
Length = 275
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 32/153 (20%)
Query: 172 PPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQ 231
PP P V P A+ P G + P +++ PGC +RP + S
Sbjct: 24 PPPPPV-------SPPALTPAPAAGEEGPAP--LSETGAPGCS---GSRPPELEPERSLG 71
Query: 232 PDEEERARLAGEEEALRQYQQ-RKQQQQEGNYLQHVQL----------DQRSLVLN---- 276
R R E+E L + ++ +++++E + H L D+ ++N
Sbjct: 72 ---RFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSEL 128
Query: 277 TEPAECPVCYSVLAPGEAVVLRECLHTFCRECL 309
T C +C L +A + ECLHTFC+ C+
Sbjct: 129 TPYILCSICKGYLI--DATTITECLHTFCKSCI 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,314,523
Number of Sequences: 37866
Number of extensions: 1371315
Number of successful extensions: 11931
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 10067
Number of HSP's gapped (non-prelim): 2024
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.