Guide to the Human Genome
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Search of human proteins with 93004078

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|93004078 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
         (578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|93004078 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]              1168   0.0  
gi|21361361 ilvB (bacterial acetolactate synthase)-like [Homo sa...   190   3e-48
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]          32   1.2  
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]          32   1.2  
gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]       32   1.6  
gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]        32   1.6  
gi|21361771 phosphatidylinositol glycan class V [Homo sapiens]         32   1.6  
gi|57165364 gametocyte specific factor 1-like isoform 2 [Homo sa...    31   3.6  
gi|167621456 kinase suppressor of ras 2 [Homo sapiens]                 30   4.6  
gi|110624787 5'-3' exoribonuclease 1 isoform b [Homo sapiens]          30   4.6  
gi|110624792 5'-3' exoribonuclease 1 isoform a [Homo sapiens]          30   4.6  

>gi|93004078 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
          Length = 578

 Score = 1168 bits (3022), Expect = 0.0
 Identities = 578/578 (100%), Positives = 578/578 (100%)

Query: 1   MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNE 60
           MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNE
Sbjct: 1   MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNE 60

Query: 61  QAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMG 120
           QAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMG
Sbjct: 61  QAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMG 120

Query: 121 AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVN 180
           AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVN
Sbjct: 121 AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVN 180

Query: 181 VNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY 240
           VNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY
Sbjct: 181 VNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY 240

Query: 241 KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVK 300
           KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVK
Sbjct: 241 KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVK 300

Query: 301 FIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSN 360
           FIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSN
Sbjct: 301 FIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSN 360

Query: 361 EAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDA 420
           EAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDA
Sbjct: 361 EAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDA 420

Query: 421 GTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV 480
           GTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV
Sbjct: 421 GTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV 480

Query: 481 NNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQK 540
           NNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQK
Sbjct: 481 NNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQK 540

Query: 541 SLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM 578
           SLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM
Sbjct: 541 SLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM 578


>gi|21361361 ilvB (bacterial acetolactate synthase)-like [Homo
           sapiens]
          Length = 632

 Score =  190 bits (483), Expect = 3e-48
 Identities = 155/586 (26%), Positives = 266/586 (45%), Gaps = 61/586 (10%)

Query: 16  GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTS 75
           G + +A  L+   V +IF +VG  ++ + +A ++LGI+ +  R+E  A +AA A+  L+ 
Sbjct: 54  GGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSG 113

Query: 76  RPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYT 135
             GV  V +GPGL + +  + NA M   P+L++GG++    +  GA Q   Q+   R   
Sbjct: 114 TVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLC 173

Query: 136 KFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPAD----FVNLQVNVNSIK------ 185
           KF      +  I   +  A+ ++  G PG  +V++P D    +  +Q  +   K      
Sbjct: 174 KFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLV 233

Query: 186 ------YMERCMSP----------------PISMAETSAVCTAASVIRNAKQPLLIIGKG 223
                 Y+E  ++                  I  A    V     ++  AK+PL+++G  
Sbjct: 234 GRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQ 293

Query: 224 AAYAHAE-ESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGAR 282
           A       + ++  VE   +P     M +G++  NHP  +   RS AL+ ADVIVL G  
Sbjct: 294 ALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTV 353

Query: 283 LNWILHFGLPPRYQPDVKFIQVDICAEELGNNV----KPAVTLLGNIHAVTKQLLEELDK 338
            ++ L +G    +    K I V+   EE+  N     KP   + G++ +   +L+E L  
Sbjct: 354 CDFRLSYGRVLSHSS--KIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQG 411

Query: 339 TPWQYPPESKWWKTLREKMKSNEAASKELASKK-SLPMNYYTVFYHVQEQLPRDCFVVSE 397
             W       W + LRE  +  E   +E A+   +  +N   V   V+E LP +  +V +
Sbjct: 412 QTWA----PDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVD 467

Query: 398 GANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSA 457
           G + +     ++Q   P   LD G FGT+GVG GFA+ A +   D      + C+ GD A
Sbjct: 468 GGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAE----VWCLFGDGA 523

Query: 458 FGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSH 517
           FG+S +E +T  R+ +P++ LV N+ G         W ++ + Q  +      C L  + 
Sbjct: 524 FGYSLIEFDTFVRHKIPVMALVGNDAG---------WTQISREQVPSLGSNVACGLAYTD 574

Query: 518 YEQVMTAFGGKGYFV--QTPEELQKSLR--QSLADTTKPSLINIMI 559
           Y +     G +G  +  +  +++ K L   Q       P ++NI+I
Sbjct: 575 YHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILI 620


>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 340 PWQYPPESKWWKTLREKMKSNEAASKELASKKS--LPMNYYTVFYHVQEQLPRDCFVVSE 397
           P Q  P  ++ +   ++  S E  SK L+      LP  +          LP+    +S 
Sbjct: 70  PGQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSR 129

Query: 398 GANTMDIGRTVLQNYLPRHRLDAGTFGTMGVG 429
            A+  DIG   L+ Y+   +L  GT+ T+  G
Sbjct: 130 RASLSDIGFGKLETYVKLDKLGEGTYATVFKG 161


>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 340 PWQYPPESKWWKTLREKMKSNEAASKELASKKS--LPMNYYTVFYHVQEQLPRDCFVVSE 397
           P Q  P  ++ +   ++  S E  SK L+      LP  +          LP+    +S 
Sbjct: 70  PGQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSR 129

Query: 398 GANTMDIGRTVLQNYLPRHRLDAGTFGTMGVG 429
            A+  DIG   L+ Y+   +L  GT+ T+  G
Sbjct: 130 RASLSDIGFGKLETYVKLDKLGEGTYATVFKG 161


>gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]
          Length = 789

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/55 (23%), Positives = 31/55 (56%)

Query: 16  GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAI 70
           G  + +  LK+ +  +  G V  P+T++ + A     +Y+GM +++ + Y A+++
Sbjct: 646 GGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASV 700


>gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]
          Length = 796

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/55 (23%), Positives = 31/55 (56%)

Query: 16  GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAI 70
           G  + +  LK+ +  +  G V  P+T++ + A     +Y+GM +++ + Y A+++
Sbjct: 653 GGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASV 707


>gi|21361771 phosphatidylinositol glycan class V [Homo sapiens]
          Length = 493

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 7/80 (8%)

Query: 134 YTKF----SARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQ---VNVNSIKY 186
           YT+F    SARP     +   ++K  R +    P  C+ D+P  +  +Q    NV  +KY
Sbjct: 260 YTQFCLPGSARPIPEPLVQLAVDKGYRIAEGNEPPWCFWDVPLIYSYIQDVYWNVGFLKY 319

Query: 187 MERCMSPPISMAETSAVCTA 206
            E    P   +A   A+  A
Sbjct: 320 YELKQVPNFLLAAPVAILVA 339


>gi|57165364 gametocyte specific factor 1-like isoform 2 [Homo
           sapiens]
          Length = 123

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 104 PLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAI 147
           PL V   SSE+N +T   F  FPQ   C   TK SAR +S + I
Sbjct: 77  PLKVSPPSSEQNDDTQQTF--FPQKVVCENDTKESARETSPQKI 118


>gi|167621456 kinase suppressor of ras 2 [Homo sapiens]
          Length = 921

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 13/66 (19%)

Query: 182 NSIKYMERCMSPPISMAETSAVC---TAASVIRNAKQPLLI---------IGKGAAYAHA 229
           N + +M  CMSPP  +A  +++C   T  SV+R+AK  L +         I KG  Y HA
Sbjct: 692 NVVLFMGACMSPP-HLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHA 750

Query: 230 EESIKK 235
           +  + K
Sbjct: 751 KGILHK 756


>gi|110624787 5'-3' exoribonuclease 1 isoform b [Homo sapiens]
          Length = 1693

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 26/108 (24%)

Query: 239 QYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHF--------- 289
           QYK  +  T MG  VV D+               AD    +   + WILH+         
Sbjct: 432 QYKRTYYMTKMGVDVVSDDF-------------LADQAACYVQAIQWILHYYYHGVQSWS 478

Query: 290 -GLPPRYQP---DVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLL 333
              P  Y P   D+  I       ELG   KP   LL  + A +K LL
Sbjct: 479 WYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLL 526


>gi|110624792 5'-3' exoribonuclease 1 isoform a [Homo sapiens]
          Length = 1706

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 26/108 (24%)

Query: 239 QYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHF--------- 289
           QYK  +  T MG  VV D+               AD    +   + WILH+         
Sbjct: 432 QYKRTYYMTKMGVDVVSDDF-------------LADQAACYVQAIQWILHYYYHGVQSWS 478

Query: 290 -GLPPRYQP---DVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLL 333
              P  Y P   D+  I       ELG   KP   LL  + A +K LL
Sbjct: 479 WYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLL 526


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,903,538
Number of Sequences: 37866
Number of extensions: 951943
Number of successful extensions: 2102
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2092
Number of HSP's gapped (non-prelim): 12
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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