Search of human proteins with 87196351

Search of human proteins with 87196351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3
[Homo sapiens]
         (662 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...  1343   0.0  
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...  1241   0.0  
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...  1241   0.0  
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   452   e-127
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   448   e-126
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   448   e-126
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         334   2e-91
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          333   4e-91
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    327   2e-89
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   293   3e-79
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  292   6e-79
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   281   1e-75
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   274   2e-73
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            268   9e-72
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            268   9e-72
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   251   1e-66
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   232   9e-61
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   216   5e-56
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   214   2e-55
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   210   4e-54
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   205   1e-52
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   204   2e-52
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   197   2e-50
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   196   7e-50
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   188   2e-47
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   187   3e-47
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   187   3e-47
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   186   8e-47
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      185   1e-46
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   181   2e-45

>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score = 1343 bits (3476), Expect = 0.0
 Identities = 662/662 (100%), Positives = 662/662 (100%)

Query: 1   MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60
           MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW
Sbjct: 1   MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60

Query: 61  SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120
           SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE
Sbjct: 61  SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120

Query: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180
           RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE
Sbjct: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240

Query: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300
           QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
Sbjct: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300

Query: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360
           YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
Sbjct: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360

Query: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420
           IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
Sbjct: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420

Query: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
           WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
Sbjct: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480

Query: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
           EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL
Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540

Query: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600
           ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR
Sbjct: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600

Query: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660
           DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
Sbjct: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660

Query: 661 GN 662
           GN
Sbjct: 661 GN 662


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 608/662 (91%), Positives = 634/662 (95%), Gaps = 2/662 (0%)

Query: 1   MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60
           MSHV V+N   LDQQ A LDLNS     G STASKGRYIPPHLRNREA+KGF+DKDSSGW
Sbjct: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60

Query: 61  SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120
           S SKDKDAYSSFGSR DSRGK  +FS+RGSGSRGRFDDRGRSDYDGIG+R +R GFG+FE
Sbjct: 61  SCSKDKDAYSSFGSR-DSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNR-ERPGFGRFE 118

Query: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180
           R G+SRWCDKS EDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATG+NCPPHIE
Sbjct: 119 RSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIE 178

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           +FSD++MGEIIMGNIELTRYTRPTPVQKHAIPIIK KRDLMACAQTGSGKTAAFLLPILS
Sbjct: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238

Query: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300
           QIY+DGPGEAL+A+KENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298

Query: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360
           YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
Sbjct: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358

Query: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420
           IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
Sbjct: 359 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 418

Query: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
           WVE+ DKRSFLLD+L ATG DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
Sbjct: 419 WVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478

Query: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
           EEALHQFRSGKSPILVATAVAARGLDISNV+HVINFDLPSDIEEYVHRIGRTGRVGNLGL
Sbjct: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538

Query: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600
           ATSFFNE+N+NITKDLLDLLVEAKQEVPSWLENMAYEHHYKG SRGRSKS+RFSGGFGAR
Sbjct: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGAR 598

Query: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660
           DYRQSSG+SSS F +SR SSSRSGGGG+G+SRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
Sbjct: 599 DYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 658

Query: 661 GN 662
           GN
Sbjct: 659 GN 660


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 608/662 (91%), Positives = 634/662 (95%), Gaps = 2/662 (0%)

Query: 1   MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW 60
           MSHV V+N   LDQQ A LDLNS     G STASKGRYIPPHLRNREA+KGF+DKDSSGW
Sbjct: 1   MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGW 60

Query: 61  SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE 120
           S SKDKDAYSSFGSR DSRGK  +FS+RGSGSRGRFDDRGRSDYDGIG+R +R GFG+FE
Sbjct: 61  SCSKDKDAYSSFGSR-DSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNR-ERPGFGRFE 118

Query: 121 RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE 180
           R G+SRWCDKS EDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATG+NCPPHIE
Sbjct: 119 RSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIE 178

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           +FSD++MGEIIMGNIELTRYTRPTPVQKHAIPIIK KRDLMACAQTGSGKTAAFLLPILS
Sbjct: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238

Query: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300
           QIY+DGPGEAL+A+KENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 298

Query: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360
           YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
Sbjct: 299 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 358

Query: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420
           IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
Sbjct: 359 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 418

Query: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
           WVE+ DKRSFLLD+L ATG DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
Sbjct: 419 WVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478

Query: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
           EEALHQFRSGKSPILVATAVAARGLDISNV+HVINFDLPSDIEEYVHRIGRTGRVGNLGL
Sbjct: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538

Query: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR 600
           ATSFFNE+N+NITKDLLDLLVEAKQEVPSWLENMAYEHHYKG SRGRSKS+RFSGGFGAR
Sbjct: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGAR 598

Query: 601 DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 660
           DYRQSSG+SSS F +SR SSSRSGGGG+G+SRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
Sbjct: 599 DYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW 658

Query: 661 GN 662
           GN
Sbjct: 659 GN 660


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  452 bits (1162), Expect = e-127
 Identities = 278/601 (46%), Positives = 369/601 (61%), Gaps = 55/601 (9%)

Query: 52  FYDKDSSGW--SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGS 109
           F D DSSG+   SS D +   +       RG +    D      G      R    G G+
Sbjct: 101 FEDGDSSGFWRESSNDCEDNPTRNRGFSKRGDNDLDPDECMQRTGGLFGSRRPVLSGTGN 160

Query: 110 RGD----RSGFGKFERGG----NSRWCDKSDEDDWSK------------------PLPPS 143
            GD    RSG G  ERGG    N      S ++ W                    P PP 
Sbjct: 161 -GDTSQSRSGSGS-ERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPP 218

Query: 144 ERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRP 203
           E  E  +F+   TGINF+KYD I VE +G++ PP I +F +  + + +  NI    YT+ 
Sbjct: 219 ED-EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKL 277

Query: 204 TPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRR 263
           TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  DG   +        R+ + 
Sbjct: 278 TPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITAS--------RF-KE 328

Query: 264 KQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVAT 323
            Q P  +++APTREL  QIY EARKFS+ + VR  V+YGG  +G  IR + +GC++L AT
Sbjct: 329 LQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCAT 388

Query: 324 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSA 383
           PGRL+D++ + KIGL   KYLVLDEADRMLDMGF P++++++    MP K  R T+MFSA
Sbjct: 389 PGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSA 448

Query: 384 TFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDS 442
           TFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V +  KR  L+++L   G D 
Sbjct: 449 TFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIG-DE 507

Query: 443 LTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAA 502
            T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+AL  FR GK P+LVAT+VAA
Sbjct: 508 RTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAA 567

Query: 503 RGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN-ERNINITKDLLDLLV 561
           RGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A SFF+ E + ++ + L+ +L 
Sbjct: 568 RGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLT 627

Query: 562 EAKQEVPSWLENMAYEHH---YKGSSRGRSKSSRFSGGFGARDYRQ-SSGASSSSFSSSR 617
           +A+Q+VP+WLE +A+  +   + GS+RG          F + D R+  S  +++ FSSS+
Sbjct: 628 DAQQDVPAWLEEIAFSTYIPGFSGSTRGNV--------FASVDTRKGKSTLNTAGFSSSQ 679

Query: 618 A 618
           A
Sbjct: 680 A 680


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  448 bits (1153), Expect = e-126
 Identities = 265/560 (47%), Positives = 356/560 (63%), Gaps = 40/560 (7%)

Query: 72  FGSR----SDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSR---GDRSGFGKFERGGN 124
           FGSR    S +    +  S  GSGS        R  Y G+      G      K E  G 
Sbjct: 182 FGSRRPVLSGTGNGDTSQSRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGG 234

Query: 125 SRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSD 184
                +  +  +  P PP +  E  +F+   TGINF+KYD I VE +G++ PP I +F +
Sbjct: 235 ESSDTQGPKVTYIPPPPPED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEE 292

Query: 185 VEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYS 244
             + + +  NI    YT+ TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  
Sbjct: 293 ANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMH 352

Query: 245 DGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGA 304
           DG   +        R+ +  Q P  +++APTREL  QIY EARKFS+ + VR  V+YGG 
Sbjct: 353 DGITAS--------RF-KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT 403

Query: 305 DIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI 364
            +G  IR + +GC++L ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P+++++
Sbjct: 404 QLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKL 463

Query: 365 VEQDTMPPKGVRHTMMFSATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVE 423
           +    MP K  R T+MFSATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V 
Sbjct: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523

Query: 424 ESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEA 483
           +  KR  L+++L   G D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+A
Sbjct: 524 QFSKREKLVEILRNIG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQA 582

Query: 484 LHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 543
           L  FR GK P+LVAT+VAARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A S
Sbjct: 583 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642

Query: 544 FFN-ERNINITKDLLDLLVEAKQEVPSWLENMAYEHH---YKGSSRGRSKSSRFSGGFGA 599
           FF+ E + ++ + L+ +L +A+Q+VP+WLE +A+  +   + GS+RG          F +
Sbjct: 643 FFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNV--------FAS 694

Query: 600 RDYRQ-SSGASSSSFSSSRA 618
            D R+  S  +++ FSSS+A
Sbjct: 695 VDTRKGKSTLNTAGFSSSQA 714


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  448 bits (1153), Expect = e-126
 Identities = 265/560 (47%), Positives = 356/560 (63%), Gaps = 40/560 (7%)

Query: 72  FGSR----SDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSR---GDRSGFGKFERGGN 124
           FGSR    S +    +  S  GSGS        R  Y G+      G      K E  G 
Sbjct: 182 FGSRRPVLSGTGNGDTSQSRSGSGSE-------RGGYKGLNEEVITGSGKNSWKSEAEGG 234

Query: 125 SRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSD 184
                +  +  +  P PP +  E  +F+   TGINF+KYD I VE +G++ PP I +F +
Sbjct: 235 ESSDTQGPKVTYIPPPPPED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEE 292

Query: 185 VEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYS 244
             + + +  NI    YT+ TPVQK++IPII   RDLMACAQTGSGKTAAFLLPIL+ +  
Sbjct: 293 ANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMH 352

Query: 245 DGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGA 304
           DG   +        R+ +  Q P  +++APTREL  QIY EARKFS+ + VR  V+YGG 
Sbjct: 353 DGITAS--------RF-KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGT 403

Query: 305 DIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRI 364
            +G  IR + +GC++L ATPGRL+D++ + KIGL   KYLVLDEADRMLDMGF P+++++
Sbjct: 404 QLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKL 463

Query: 365 VEQDTMPPKGVRHTMMFSATFPKEIQMLARDFL-DEYIFLAVGRVGSTSENITQKVVWVE 423
           +    MP K  R T+MFSATFP+EIQ LA +FL   Y+F+AVG+VG    ++ Q V+ V 
Sbjct: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523

Query: 424 ESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEA 483
           +  KR  L+++L   G D  T+VFVETKK AD +  FL  E  + TSIHGDR QR+RE+A
Sbjct: 524 QFSKREKLVEILRNIG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQA 582

Query: 484 LHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATS 543
           L  FR GK P+LVAT+VAARGLDI NV+HVINFDLPS I+EYVHRIGRTGR GN G A S
Sbjct: 583 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642

Query: 544 FFN-ERNINITKDLLDLLVEAKQEVPSWLENMAYEHH---YKGSSRGRSKSSRFSGGFGA 599
           FF+ E + ++ + L+ +L +A+Q+VP+WLE +A+  +   + GS+RG          F +
Sbjct: 643 FFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNV--------FAS 694

Query: 600 RDYRQ-SSGASSSSFSSSRA 618
            D R+  S  +++ FSSS+A
Sbjct: 695 VDTRKGKSTLNTAGFSSSQA 714


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  334 bits (856), Expect = 2e-91
 Identities = 205/511 (40%), Positives = 286/511 (55%), Gaps = 45/511 (8%)

Query: 172 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
           G+ CP  + +F      + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222

Query: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269

Query: 292 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 351
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329

Query: 352 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 410
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 330 MLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385

Query: 411 TSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHEGYAC 468
            + NI Q V    ES+K   L+ L+      K++ T++FVETK+  D L   +  +G+  
Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445

Query: 469 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHR 528
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +VK VIN+D P+  E+YVHR
Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505

Query: 529 IGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRS 588
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +  +H   G   G+ 
Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564

Query: 589 KSSRFSGGFGARDYR--------------QSSGASSSSFSSSRASSSRSG---GGGHGSS 631
             SR+     A +                +  G   S+    R+ + R+G   G G+GS 
Sbjct: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624

Query: 632 RGFGGGGYG------GFYNSDGYG-GNYNSQ 655
               G   G      G Y +  YG  +Y +Q
Sbjct: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  333 bits (853), Expect = 4e-91
 Identities = 206/508 (40%), Positives = 284/508 (55%), Gaps = 41/508 (8%)

Query: 172 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
           G+ CP  + +F      + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222

Query: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269

Query: 292 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 351
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329

Query: 352 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 410
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 330 MLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385

Query: 411 TSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHEGYAC 468
            + NI Q V    ES+K   L+ L+      K++ T++FVETK+  D L   +  +G+  
Sbjct: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445

Query: 469 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHR 528
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +VK VIN+D P+  E+YVHR
Sbjct: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505

Query: 529 IGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRS 588
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +       G   GRS
Sbjct: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRS 565

Query: 589 KSSRFSGGFGAR-------DYR----QSSGASSSSFSSSRASSSRSG---GGGHGSSRGF 634
           +    S             D R    +  G   S+    R+ + R+G   G G+GS    
Sbjct: 566 RYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSA 625

Query: 635 GGGGYG------GFYNSDGYG-GNYNSQ 655
            G   G      G Y +  YG  +Y +Q
Sbjct: 626 FGAQAGQYTYGQGTYGAAAYGTSSYTAQ 653


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  327 bits (839), Expect = 2e-89
 Identities = 198/500 (39%), Positives = 280/500 (56%), Gaps = 37/500 (7%)

Query: 168 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 227
           +   G+NCP  + +F +      +M  I    +T PT +Q    P+     D++  AQTG
Sbjct: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141

Query: 228 SGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 287
           SGKT ++LLP +  I              +  +  R   PI LVLAPTRELA Q+ + A 
Sbjct: 142 SGKTLSYLLPAIVHI-------------NHQPFLERGDGPICLVLAPTRELAQQVQQVAA 188

Query: 288 KFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 347
           ++    R++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L    YLVLD
Sbjct: 189 EYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLD 248

Query: 348 EADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 407
           EADRMLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +YI + +G 
Sbjct: 249 EADRMLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGA 304

Query: 408 VG-STSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHE 464
           +  S + NI Q V    + +K   L+ L+    + K++ T+VFVETK+  D L   +  +
Sbjct: 305 LELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRD 364

Query: 465 GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEE 524
           G+    IHGD+SQ++R+  L++F+ GK+PIL+AT VA+RGLD+ +VK VIN+D P+  E+
Sbjct: 365 GWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSED 424

Query: 525 YVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 584
           Y+HRIGRT R    G A +FF   NI    DL+ +L EA Q +   L  +  E    G S
Sbjct: 425 YIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLV-EDRGSGRS 483

Query: 585 RGRSKSSRFSGGFGARDYRQS--SGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGF 642
           RGR          G +D R+   S      F++ R   +   G      R FG     G 
Sbjct: 484 RGRG---------GMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGV 534

Query: 643 YNSDGY-----GGNYNSQGV 657
           Y++  Y     G N+ S G+
Sbjct: 535 YSAANYTNGSFGSNFVSAGI 554


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  293 bits (751), Expect = 3e-79
 Identities = 173/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%)

Query: 149 ELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQK 208
           EL       +N  + +   +   G  CP  I+S+    +   I+ +++   Y +PTP+Q 
Sbjct: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400

Query: 209 HAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPI 268
            AIP I   RDL+  A+TGSGKT AFLLP+   I         R+++E        + PI
Sbjct: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447

Query: 269 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 328
           ++++ PTRELA+QI +E +KFS    +R   VYGG  I +QI +L+RG  ++V TPGR++
Sbjct: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507

Query: 329 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 385
           DM+    G++  L    Y+VLDEADRM DMGFEPQ+ RIV  D + P   R T+MFSATF
Sbjct: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563

Query: 386 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTL 445
           P+ ++ LAR  L + I + VG       ++ Q+V+ +EE  K   LL+LL    +    +
Sbjct: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623

Query: 446 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
           +FV+ ++ AD L   L    Y C S+HG   Q DR+  ++ F++G   +LVAT+VAARGL
Sbjct: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683

Query: 506 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQ 565
           D+ ++  V+N+  P+  E+YVHR GRTGR GN G A +F  E       D++  L  +  
Sbjct: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743

Query: 566 EVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYR 603
            VP  LE +  +  +K   +   K  + S GF  + ++
Sbjct: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  292 bits (748), Expect = 6e-79
 Identities = 170/439 (38%), Positives = 253/439 (57%), Gaps = 30/439 (6%)

Query: 172 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
           G+  PP I+SF +++    I+  ++      PTP+Q   IP I   RD++  A TGSGKT
Sbjct: 173 GDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKT 232

Query: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELA------VQIYEE 285
             F LP++  ++     + L   K  G YG        L++ P+RELA      ++ Y  
Sbjct: 233 LVFTLPVI--MFCLEQEKRLPFSKREGPYG--------LIICPSRELARQTHGILEYYCR 282

Query: 286 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 345
             +      +R  +  GG  + +Q+  +  G H++VATPGRL+D++++  + LD C+YL 
Sbjct: 283 LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLA 342

Query: 346 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405
           LDEADRM+DMGFE  IR I        KG R T++FSAT PK+IQ  A+  L + + + V
Sbjct: 343 LDEADRMIDMGFEGDIRTIFSYF----KGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398

Query: 406 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 465
           GR G+ S ++ Q+V +V+E  K  +LL+ L  T      L+F E K   D++ ++L  +G
Sbjct: 399 GRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPP--VLIFAEKKADVDAIHEYLLLKG 456

Query: 466 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525
               +IHG + Q +R +A+  FR GK  +LVAT VA++GLD   ++HVIN+D+P +IE Y
Sbjct: 457 VEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENY 516

Query: 526 VHRIGRTGRVGNLGLATSFFNER-NINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 584
           VHRIGRTGR GN G+AT+F N+  + ++  DL  LL+EAKQ+VP  L+ +    H    S
Sbjct: 517 VHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL----HCGDES 572

Query: 585 R---GRSKSSRFSGGFGAR 600
               G  +   F GG G R
Sbjct: 573 MLDIGGERGCAFCGGLGHR 591


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  281 bits (719), Expect = 1e-75
 Identities = 168/443 (37%), Positives = 240/443 (54%), Gaps = 33/443 (7%)

Query: 164 DDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMAC 223
           +D  +   G   P  I S+ D  +   I+  I+   Y  PTP+Q+ AIPI  + RD++  
Sbjct: 375 EDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGV 434

Query: 224 AQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIY 283
           A+TGSGKTAAFL+P+L  I +         + +  R     Q P +++LAPTRELA QI 
Sbjct: 435 AETGSGKTAAFLIPLLVWITT---------LPKIDRIEESDQGPYAIILAPTRELAQQIE 485

Query: 284 EEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKY 343
           EE  KF     +R   V GG     Q   L  GC +++ATPGRL+D++E   + L  C Y
Sbjct: 486 EETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTY 545

Query: 344 LVLDEADRMLDMGFEPQIRRIVEQDTM------------PPKGV----------RHTMMF 381
           +VLDEADRM+DMGFEP +++I+E   +            P K +          R T+MF
Sbjct: 546 VVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMF 605

Query: 382 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKD 441
           +AT P  ++ LAR +L     + +G  G   E + QKV  + ES+KR  LL +L   G D
Sbjct: 606 TATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQ-GFD 664

Query: 442 SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 501
              ++FV  KKG D L   L   GY   ++HG + Q  RE AL   ++G   ILVAT VA
Sbjct: 665 PPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVA 724

Query: 502 ARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLV 561
            RG+DI +V  V+N+D+  +IE+Y+HRIGRTGR G  G+A +F  + +  +  +L   ++
Sbjct: 725 GRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAIL 784

Query: 562 EAK-QEVPSWLENMAYEHHYKGS 583
           E+     P  L N     H  G+
Sbjct: 785 ESPVSSCPPELANHPDAQHKPGT 807


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  274 bits (700), Expect = 2e-73
 Identities = 156/386 (40%), Positives = 229/386 (59%), Gaps = 18/386 (4%)

Query: 191 IMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEA 250
           +M NI+   + +PTP+Q  A PI+ +  DL+  AQTG+GKT  +L+P             
Sbjct: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGF----------- 301

Query: 251 LRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 310
           +  + +    G+R + P  LVL PTRELA+Q+  E  K+SY+  +R   VYGG +  +QI
Sbjct: 302 IHLVLQPSLKGQRNR-PGMLVLTPTRELALQVEGECCKYSYKG-LRSVCVYGGGNRDEQI 359

Query: 311 RDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTM 370
            +L++G  +++ATPGRL D+     + L    YLVLDEAD+MLDMGFEPQI +I+  D  
Sbjct: 360 EELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL-LDVR 418

Query: 371 PPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEESDKRS 429
           P    R T+M SAT+P  +  LA+ +L E + + VG +   +  ++ Q ++   E +K S
Sbjct: 419 PD---RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475

Query: 430 FLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRS 489
            +   L +       +VFV  K  AD L   L     +  S+HGDR QRDRE+AL  F++
Sbjct: 476 HMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKT 535

Query: 490 GKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERN 549
           GK  IL+AT +A+RGLD+ +V HV NFD P +IEEYVHRIGRTGR G  G++ +     +
Sbjct: 536 GKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRND 595

Query: 550 INITKDLLDLLVEAKQEVPSWLENMA 575
             +  +L+++L  A Q +P  L +MA
Sbjct: 596 WRVASELINILERANQSIPEELVSMA 621


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  268 bits (686), Expect = 9e-72
 Identities = 161/437 (36%), Positives = 238/437 (54%), Gaps = 25/437 (5%)

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           SF+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TGSGKTAAF+ P+L 
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313

Query: 241 QIYSDG---PGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297
            I       PG+                 PI++++ PTREL  QI+ E ++F     +R 
Sbjct: 314 HIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHAECKRFGKAYNLRS 357

Query: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357
             VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YLV DEADRM DMGF
Sbjct: 358 VAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGF 417

Query: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
           E Q+R I        +  R T++FSATF K+I+ LARD L + I +  G +G  +E++TQ
Sbjct: 418 EYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQ 473

Query: 418 KVVWVEES-DKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRS 476
            V  +     K ++L   L         L+FV  K  A+ L + L  EG+    +HGD  
Sbjct: 474 IVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMD 533

Query: 477 QRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
           Q +R + +  F+    P+LVAT VAARGLDI ++K VIN+D+  DI+ + HRIGRTGR G
Sbjct: 534 QSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAG 593

Query: 537 NLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGR-SKSSRFSG 595
             G+A +    ++ N   DL+  L  A Q V   L ++A ++ +   SR +  K  + + 
Sbjct: 594 EKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNI 653

Query: 596 GFGARDYRQSSGASSSS 612
           G G   YR+  G  S +
Sbjct: 654 GGGGLGYRERPGLGSEN 670


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  268 bits (686), Expect = 9e-72
 Identities = 161/437 (36%), Positives = 238/437 (54%), Gaps = 25/437 (5%)

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           SF+     E +M  I  + YT+PTP+Q   +P+    RD++  A+TGSGKTAAF+ P+L 
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313

Query: 241 QIYSDG---PGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297
            I       PG+                 PI++++ PTREL  QI+ E ++F     +R 
Sbjct: 314 HIMDQKELEPGDG----------------PIAVIVCPTRELCQQIHAECKRFGKAYNLRS 357

Query: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357
             VYGG  + +Q + L+ G  ++V TPGRL+D +++    L    YLV DEADRM DMGF
Sbjct: 358 VAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGF 417

Query: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
           E Q+R I        +  R T++FSATF K+I+ LARD L + I +  G +G  +E++TQ
Sbjct: 418 EYQVRSIASH----VRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQ 473

Query: 418 KVVWVEES-DKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRS 476
            V  +     K ++L   L         L+FV  K  A+ L + L  EG+    +HGD  
Sbjct: 474 IVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMD 533

Query: 477 QRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
           Q +R + +  F+    P+LVAT VAARGLDI ++K VIN+D+  DI+ + HRIGRTGR G
Sbjct: 534 QSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAG 593

Query: 537 NLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGR-SKSSRFSG 595
             G+A +    ++ N   DL+  L  A Q V   L ++A ++ +   SR +  K  + + 
Sbjct: 594 EKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNI 653

Query: 596 GFGARDYRQSSGASSSS 612
           G G   YR+  G  S +
Sbjct: 654 GGGGLGYRERPGLGSEN 670


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  251 bits (642), Expect = 1e-66
 Identities = 144/395 (36%), Positives = 220/395 (55%), Gaps = 18/395 (4%)

Query: 202 RPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 261
           +PTP+Q  A PII +  DL+  AQTG+GKT ++L+P    + S    + +   + NG   
Sbjct: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDS----QPISREQRNG--- 296

Query: 262 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 321
                P  LVL PTRELA+ +  E  K+SY+     C+ YGG +   QI D+ +G  +++
Sbjct: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350

Query: 322 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 381
           ATPGRL D+     + L    YLV+DEAD+MLDM FEPQIR+I+  D  P    R T+M 
Sbjct: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406

Query: 382 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEESDKRSFLLDLLNATGK 440
           SAT+P  ++ LA  +L + + + VG +   + N + Q ++   E +KR+   + +     
Sbjct: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466

Query: 441 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 500
           +   ++FV  K  AD L      +G +  S+HG+  Q D+E A+  F+SG   IL+ T +
Sbjct: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526

Query: 501 AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLL 560
            +RGLD+++V HV N+D P +I+ YVHR+G  GR G  G + +   +R+  +  +L+ +L
Sbjct: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586

Query: 561 VEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSG 595
             A Q VP  L  MA ++      R R   SR  G
Sbjct: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  232 bits (591), Expect = 9e-61
 Identities = 144/417 (34%), Positives = 230/417 (55%), Gaps = 25/417 (5%)

Query: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238
           I  F    + E++  N++ + Y  PTP+Q   IP+    RD++A A TGSGKTAAFLLP+
Sbjct: 202 IIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPV 261

Query: 239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF-SYRSRVRP 297
           +           +RA+ E+       + P +L+L PTRELA+QI  +A++  S   R++ 
Sbjct: 262 I-----------MRALFES-------KTPSALILTPTRELAIQIERQAKELMSGLPRMKT 303

Query: 298 CVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357
            ++ GG  +  Q+  L++   +++ATPGRL+D++++  + L   K +V+DEAD ML MGF
Sbjct: 304 VLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGF 363

Query: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
           + Q+  I+E     P   + T++ SAT P  I+ LA   L   + +  G       N+ Q
Sbjct: 364 QQQVLDILENI---PNDCQ-TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQ 419

Query: 418 KVVWVEESDKRSFLLDLLNATGK-DSLTLVFVETKKGADSLEDFLYH-EGYACTSIHGDR 475
            ++WVE+  K+  L ++LN         LVFV+ K GAD L + +    G    SIH ++
Sbjct: 420 IILWVEDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEK 479

Query: 476 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRV 535
           SQ +R+  L     G   ++V+T V  RGLD+ +V+ V+NFD+PS ++EYVH+IGR GR+
Sbjct: 480 SQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRL 539

Query: 536 GNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSR 592
           G  G A +F N  +  +  D+   +      +P  L N  Y H  K   + + K ++
Sbjct: 540 GQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQ 596


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  216 bits (550), Expect = 5e-56
 Identities = 137/383 (35%), Positives = 203/383 (53%), Gaps = 28/383 (7%)

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           SF D+ +   ++  I    + +PTP+QK  IP+    +D+ ACA TG+GKTAAF LP+L 
Sbjct: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278

Query: 241 QIYSDGPGEALRAMKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 298
           ++                   + +Q P++  LVL PTREL +Q++   R+ +    +  C
Sbjct: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321

Query: 299 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 357
           +  GG D+  Q   L     +L+ATPGRL+D +       L   + L+LDEADRMLD  F
Sbjct: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381

Query: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
           E Q++ I+   +      R TM+FSAT   E++ LA   L   + + V      +  + Q
Sbjct: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437

Query: 418 KVVWVE---ESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 474
           + + +    E D+ + +  LL  T  D + L F +TKK A  +   L   G     +HG+
Sbjct: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496

Query: 475 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
            SQ  R EAL +F+  +  ILVAT VAARGLDI  VK VINF +P+ I+ YVHR+GRT R
Sbjct: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556

Query: 535 VGNLGLATSFFNERNINITKDLL 557
            G  G + S   E    + K+++
Sbjct: 557 AGRAGRSVSLVGEDERKMLKEIV 579


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  214 bits (545), Expect = 2e-55
 Identities = 131/382 (34%), Positives = 210/382 (54%), Gaps = 24/382 (6%)

Query: 180 ESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPIL 239
           ++F D+ + +++    +   +T+PT +Q  AIP+  + RD++  A+TGSGKT AF LPIL
Sbjct: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83

Query: 240 SQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 299
           + +                      Q   +LVL PTRELA QI E+         V+  V
Sbjct: 84  NALLET------------------PQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125

Query: 300 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 358
           + GG D   Q   L +  H+++ATPGRL+D +E  K   L   KYLV+DEADR+L+M FE
Sbjct: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185

Query: 359 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 418
            ++ +I++   + P+  R T +FSAT  K++Q L R  L   +  AV     T E + Q 
Sbjct: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241

Query: 419 VVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 478
            +++    K ++L+ +LN    +S  ++F  T          L + G+    +HG  SQ 
Sbjct: 242 YIFIPSKFKDTYLVYILNELAGNSF-MIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300

Query: 479 DREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL 538
            R  +L++F++    IL+AT VA+RGLDI +V  V+NFD+P+  ++Y+HR+GRT R G  
Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360

Query: 539 GLATSFFNERNINITKDLLDLL 560
           G A +F  + ++ + + +  L+
Sbjct: 361 GKAITFVTQYDVELFQRIEHLI 382


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  210 bits (534), Expect = 4e-54
 Identities = 139/413 (33%), Positives = 215/413 (52%), Gaps = 32/413 (7%)

Query: 156 TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIK 215
           T + FE  +++ V  T          F  + + E ++  I    + +P+ +Q+ AI  I 
Sbjct: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73

Query: 216 EKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPT 275
           + RD++A +Q+G+GKTA F + +L  +                   R  Q   +L+LAPT
Sbjct: 74  KGRDVIAQSQSGTGKTATFSISVLQCLDIQV---------------RETQ---ALILAPT 115

Query: 276 RELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK 335
           RELAVQI +          V+     GG ++G+ IR L+ G H++  TPGR+ DM+ R  
Sbjct: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRS 175

Query: 336 IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARD 395
           +     K LVLDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +   
Sbjct: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTNK 231

Query: 396 FLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGAD 455
           F+ + I + V R   T E I Q  V VE  + +   L  L  T   +  ++F  TK+  D
Sbjct: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVD 291

Query: 456 SLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVIN 515
            L + +    +  +S+HGD  Q++RE  + +FRSG S +L++T V ARGLD+  V  +IN
Sbjct: 292 WLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN 351

Query: 516 FDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 568
           +DLP++ E Y+HRIGR+GR G  G+A +F    +I I +D+         E+P
Sbjct: 352 YDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  205 bits (521), Expect = 1e-52
 Identities = 144/467 (30%), Positives = 240/467 (51%), Gaps = 38/467 (8%)

Query: 120 ERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDI----PVEATGNNC 175
           E G   +W    +     K +    + E +L SG    +  EK + +     +   G + 
Sbjct: 101 EEGATIQWMSSVEAKIEDKKV----QRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL 156

Query: 176 PPHIESFSDVE----MGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
           P  I +F  ++    +   ++ NI    +  PTP+Q  AIP++   R+L+A A TGSGKT
Sbjct: 157 PDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKT 216

Query: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291
            AF +PIL Q+            K+    G R     +L+++PTRELA QI+ E  K S 
Sbjct: 217 LAFSIPILMQL------------KQPANKGFR-----ALIISPTRELASQIHRELIKISE 259

Query: 292 RSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFC--KYLVLDE 348
            +  R  +++  A   ++      +   +LV TP RL+ ++++   G+D    ++LV+DE
Sbjct: 260 GTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319

Query: 349 ADRMLD---MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405
           +D++ +    GF  Q+  I    T     VR  M FSATF  +++   +  LD  I +++
Sbjct: 320 SDKLFEDGKTGFRDQLASIFLACTSHK--VRRAM-FSATFAYDVEQWCKLNLDNVISVSI 376

Query: 406 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 465
           G   S  E + Q++++V     +   +  L   G +   LVFV++ + A  L   L +EG
Sbjct: 377 GARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEG 436

Query: 466 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525
                IH +R+Q+ R+  +H FR+GK  +L+ TA+ ARG+D   V  VIN+D P+   EY
Sbjct: 437 INVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEY 496

Query: 526 VHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLE 572
           +HRIGRTGR GN G A +FF E +  + + + +++ +A   VP +++
Sbjct: 497 IHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIK 543


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  204 bits (520), Expect = 2e-52
 Identities = 140/440 (31%), Positives = 232/440 (52%), Gaps = 34/440 (7%)

Query: 147 EQELFSGGNTGINFEKYDDI----PVEATGNNCPPHIESFSDVE----MGEIIMGNIELT 198
           E +L SG    +  EK + +     +   G + P  I +F  ++    +   ++ NI   
Sbjct: 16  ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 75

Query: 199 RYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENG 258
            +  PTP+Q  AIP++   R+L+A A TGSGKT AF +PIL Q+            K+  
Sbjct: 76  GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 123

Query: 259 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 317
             G R     +L+++PTRELA QI+ E  K S  +  R  +++  A   ++      +  
Sbjct: 124 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 178

Query: 318 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 372
            +LV TP RL+ ++++   G+D    ++LV+DE+D++ +    GF  Q+  I    T   
Sbjct: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238

Query: 373 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLL 432
             VR  M FSATF  +++   +  LD  I +++G   S  E + Q++++V     +   +
Sbjct: 239 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 295

Query: 433 DLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 492
             L   G +   LVFV++ + A  L   L +EG     IH +R+Q+ R+  +H FR+GK 
Sbjct: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355

Query: 493 PILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINI 552
            +L+ TA+ ARG+D   V  VIN+D P+   EY+HRIGRTGR GN G A +FF E +  +
Sbjct: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 415

Query: 553 TKDLLDLLVEAKQEVPSWLE 572
            + + +++ +A   VP +++
Sbjct: 416 LRSVANVIQQAGCPVPEYIK 435


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  197 bits (502), Expect = 2e-50
 Identities = 124/391 (31%), Positives = 208/391 (53%), Gaps = 23/391 (5%)

Query: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238
           ++SF D+ + E ++  I    + +P+ +Q+ AI    +  D++A AQ+G+GKTA F + I
Sbjct: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90

Query: 239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPC 298
           L QI  D     L+A +             +LVLAPTRELA QI +              
Sbjct: 91  LQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGDYMGASCH 132

Query: 299 VVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357
              GG ++  +++ L+    H++V TPGR+ DM+ R  +   + K  VLDEAD ML  GF
Sbjct: 133 ACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGF 192

Query: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
           + QI  I ++     + V    + SAT P ++  + + F+ + I + V +   T E I Q
Sbjct: 193 KDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248

Query: 418 KVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQ 477
             + VE  + +   L  L  T   +  ++F+ T++  D L + ++   +  +++HGD  Q
Sbjct: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308

Query: 478 RDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGN 537
           ++R+  + +FRSG S +L+ T + ARG+D+  V  VIN+DLP++ E Y+HRIGR GR G 
Sbjct: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368

Query: 538 LGLATSFFNERNINITKDLLDLLVEAKQEVP 568
            G+A +   E +    +D+      + +E+P
Sbjct: 369 KGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  196 bits (497), Expect = 7e-50
 Identities = 130/421 (30%), Positives = 218/421 (51%), Gaps = 26/421 (6%)

Query: 152 SGGNTGINFEKYDDIPVEATG---NNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQK 208
           SGG+   N E      ++  G   +N    +++F D+ + E ++  I    + +P+ +Q+
Sbjct: 2   SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61

Query: 209 HAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPI 268
            AI    +  D++A AQ+G+GKTA F + IL Q+  +         KE            
Sbjct: 62  RAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ---------- 103

Query: 269 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRL 327
           +LVLAPTRELA QI +                 GG ++  +++ L+    H++V TPGR+
Sbjct: 104 ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRV 163

Query: 328 VDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 387
            DM+ R  +   + K  VLDEAD ML  GF+ QI  I ++     + V    + SAT P 
Sbjct: 164 FDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMPT 219

Query: 388 EIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVF 447
           ++  + + F+ + I + V +   T E I Q  + VE  + +   L  L  T   +  ++F
Sbjct: 220 DVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIF 279

Query: 448 VETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDI 507
           + T++  D L + ++   +  +++HGD  Q++R+  + +FRSG S +L+ T + ARG+D+
Sbjct: 280 LNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 339

Query: 508 SNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEV 567
             V  VIN+DLP++ E Y+HRIGR GR G  G+A +F  E +  I +D+        +E+
Sbjct: 340 QQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEM 399

Query: 568 P 568
           P
Sbjct: 400 P 400


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  188 bits (477), Expect = 2e-47
 Identities = 140/447 (31%), Positives = 214/447 (47%), Gaps = 47/447 (10%)

Query: 129 DKSDEDDWSKPLPPSERLEQELFSGGNT---------GINFEKYDDIPVEATGNNCPPHI 179
           ++  E++   P P   + E+E+   G T         G    + D  P EA        I
Sbjct: 118 EEPSEEEIDAPKPKKMKKEKEM--NGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEI 175

Query: 180 ESFSDVEMGEIIMGNIELTRYTRPT----------PVQKHAIPIIKEKRDLMACAQTGSG 229
           E    VE  E    N  ++  T             P+Q      +   +DL+A A+TG+G
Sbjct: 176 EQEIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTG 235

Query: 230 KTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKF 289
           KT +F +P++ +++ +          ++ + GR  Q    LVLAPTRELA Q+ ++    
Sbjct: 236 KTFSFAIPLIEKLHGE---------LQDRKRGRAPQV---LVLAPTRELANQVSKDFSDI 283

Query: 290 SYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEA 349
           + +  V     YGG   G Q   +  G  +LV TPGR+ D ++ GK+ L   K++VLDE 
Sbjct: 284 TKKLSV--ACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEV 341

Query: 350 DRMLDMGFEPQIRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIF 402
           D+MLDMGF  Q+  I+        +    T++FSAT P  +  +A+ ++       + I 
Sbjct: 342 DQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIG 401

Query: 403 LAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNA-TGKDSLTLVFVETKKGADSLEDFL 461
               +   T E++  K  W + +   + + D++   +G    T++F ETKK A  L    
Sbjct: 402 KKTQKTAITVEHLAIKCHWTQRA---AVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNS 458

Query: 462 YHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSD 521
             +  A  S+HGD  Q+ RE  L  FR+G   +LVAT VAARGLDI  V  VI    P D
Sbjct: 459 AIKQDA-QSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKD 517

Query: 522 IEEYVHRIGRTGRVGNLGLATSFFNER 548
           +E Y+HR GRTGR G  G+   F+  +
Sbjct: 518 VESYIHRSGRTGRAGRTGVCICFYQHK 544


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  187 bits (475), Expect = 3e-47
 Identities = 120/358 (33%), Positives = 185/358 (51%), Gaps = 21/358 (5%)

Query: 200 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGR 259
           Y  PTP+Q+  IP+I + +D++A A+TGSGKTA FLLP+  ++ +       RA      
Sbjct: 116 YKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGARA------ 169

Query: 260 YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 319
                     L+L+PTRELA+Q  +  ++    + ++  ++ GG  +  Q   L     +
Sbjct: 170 ----------LILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDI 219

Query: 320 LVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTM 379
           ++ATPGRLV +     + L   +Y+V DEADR+ +MGF  Q++ I+ +  +P  G   T+
Sbjct: 220 IIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR--LP--GGHQTV 275

Query: 380 MFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLL-NAT 438
           +FSAT PK +   AR  L E + + +      +E +      V E  K + LL LL N  
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV 335

Query: 439 GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVAT 498
                T+VFV TK  A+ L + L  +  +C  I+       R+  L +F  GK   L+ T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395

Query: 499 AVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDL 556
            +AARGLDI  + +VIN+  P+  + ++HR+GR  R G  G A S      I    DL
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  187 bits (475), Expect = 3e-47
 Identities = 120/358 (33%), Positives = 185/358 (51%), Gaps = 21/358 (5%)

Query: 200 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGR 259
           Y  PTP+Q+  IP+I + +D++A A+TGSGKTA FLLP+  ++ +       RA      
Sbjct: 116 YKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGARA------ 169

Query: 260 YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 319
                     L+L+PTRELA+Q  +  ++    + ++  ++ GG  +  Q   L     +
Sbjct: 170 ----------LILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDI 219

Query: 320 LVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTM 379
           ++ATPGRLV +     + L   +Y+V DEADR+ +MGF  Q++ I+ +  +P  G   T+
Sbjct: 220 IIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR--LP--GGHQTV 275

Query: 380 MFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLL-NAT 438
           +FSAT PK +   AR  L E + + +      +E +      V E  K + LL LL N  
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV 335

Query: 439 GKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVAT 498
                T+VFV TK  A+ L + L  +  +C  I+       R+  L +F  GK   L+ T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395

Query: 499 AVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDL 556
            +AARGLDI  + +VIN+  P+  + ++HR+GR  R G  G A S      I    DL
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  186 bits (471), Expect = 8e-47
 Identities = 126/372 (33%), Positives = 193/372 (51%), Gaps = 29/372 (7%)

Query: 202 RPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 261
           +PTPVQ   IP I E RD + CA+TGSGKTAAF+LPIL ++  D  G             
Sbjct: 24  QPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGI------------ 71

Query: 262 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 321
                   LVL PTRELA QI E+ R       ++ C++ GG D+  Q  +L R  H+++
Sbjct: 72  ------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVI 125

Query: 322 ATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---FEPQIRRIVEQDTMPPKGVRH 377
           ATPGRL D +       +   ++LV+DEADR+L+ G   F   +  I+    +P +  R 
Sbjct: 126 ATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILA--AVPAR--RQ 181

Query: 378 TMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNA 437
           T++FSAT    ++ L     ++  F       ST E + Q+ + V E  K ++L+ L+  
Sbjct: 182 TLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQR 241

Query: 438 ---TGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPI 494
                +D   ++F  T K    L   L    +   ++H    Q++R  AL +F+S    I
Sbjct: 242 FQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRI 301

Query: 495 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITK 554
           L+AT VA+RGLDI  V+ VIN + P   + Y+HR+GRT R G  G A +   + +I++  
Sbjct: 302 LIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVH 361

Query: 555 DLLDLLVEAKQE 566
            + + + +  +E
Sbjct: 362 AIEEQIKKKLEE 373


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  185 bits (469), Expect = 1e-46
 Identities = 119/376 (31%), Positives = 194/376 (51%), Gaps = 26/376 (6%)

Query: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
           +FS+  + E  +  ++    T   P+Q      + E +DL+A A+TG+GKT +F +P++ 
Sbjct: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197

Query: 241 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 300
           ++            + N    ++ + P  LVLAPTRELA Q+ ++ +  + +  V     
Sbjct: 198 RL------------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSV--ACF 243

Query: 301 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 360
           YGG     QI  +  G  +LV TPGR+ D ++ G++ L   +++VLDE D+MLD+GF  Q
Sbjct: 244 YGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 303

Query: 361 IRRIVEQD-TMPPKGVRHTMMFSATFPKEIQMLARDFLD------EYIFLAVGRVGSTSE 413
           +  I+ +      +    T++FSAT P+ +  +A+ ++       + +     +  +T E
Sbjct: 304 VEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 363

Query: 414 NITQKVVWVEESDKRSFLLDLLNA-TGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIH 472
           ++  +  W   S + + + D+L   +G +   ++F ETKK    +     H       +H
Sbjct: 364 HLAIQCHW---SQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMA-MNPHIKQNAQCLH 419

Query: 473 GDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRT 532
           GD +Q  RE  L  FR G   +LVAT VAARGLDI  V  VI    P D+E Y+HR GRT
Sbjct: 420 GDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRT 479

Query: 533 GRVGNLGLATSFFNER 548
           GR G  G+   F+  R
Sbjct: 480 GRAGRTGICICFYQPR 495



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 7/78 (8%)

Query: 52  FYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRG 111
           +YD ++S  S+S+ +  +SS   RS   G+S   S   SG + R   R  S  DG    G
Sbjct: 667 YYDGNTS--SNSRQRSGWSS--GRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSG 722

Query: 112 DRSGFGKFERGGNSRWCD 129
           +R+   +   GG+ R  D
Sbjct: 723 NRN---RSRSGGHKRSFD 737


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  181 bits (459), Expect = 2e-45
 Identities = 121/393 (30%), Positives = 204/393 (51%), Gaps = 26/393 (6%)

Query: 189 EIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPG 248
           E++MG  E+  + +P+P+Q+ +IPI    RD++A A+ G+GK+ A+L+P+L         
Sbjct: 106 ELLMGIFEMG-WEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL--------- 155

Query: 249 EALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIG 307
           E L   K+N +         ++V+ PTRELA+Q+ +   + S +    +     GG ++ 
Sbjct: 156 ERLDLKKDNIQ---------AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR 206

Query: 308 QQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ 367
             I  L+   H+++ATPGR++D++++G   +D  + +VLDEAD++L   F   +  I+  
Sbjct: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIIL- 265

Query: 368 DTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDK 427
            T+P    R  +++SATFP  +Q      L +   + +     T + +TQ   +V E  K
Sbjct: 266 -TLPKN--RQILLYSATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQK 321

Query: 428 RSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF 487
              L  L +   + + +++F  + +  + L   +   GY+C  IH    Q  R    H F
Sbjct: 322 VHCLNTLFSRL-QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380

Query: 488 RSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNE 547
           R+G    LV T +  RG+DI  V  VINFD P   E Y+HRIGR+GR G+LGLA +    
Sbjct: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY 440

Query: 548 RNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 580
            +    K + + L    + +PS ++   Y   Y
Sbjct: 441 DDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEY 473


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,020,007
Number of Sequences: 37866
Number of extensions: 1251850
Number of successful extensions: 12467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 270
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 6181
Number of HSP's gapped (non-prelim): 3402
length of query: 662
length of database: 18,247,518
effective HSP length: 109
effective length of query: 553
effective length of database: 14,120,124
effective search space: 7808428572
effective search space used: 7808428572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.