Search of human proteins with 83700225

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo
sapiens]
         (1039 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]  2053   0.0  
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]  1330   0.0  
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]   1330   0.0  
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...  1329   0.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]            1328   0.0  
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...  1326   0.0  
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]  1321   0.0  
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...  1249   0.0  
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   347   4e-95
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   347   4e-95
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   347   4e-95
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   347   4e-95
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   347   4e-95
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   347   4e-95
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   347   4e-95
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   338   2e-92
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   338   2e-92
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   333   4e-91
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   333   4e-91
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   326   6e-89
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   326   6e-89
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   326   6e-89
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   326   6e-89
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   324   2e-88
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   308   1e-83
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   278   2e-74
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...   249   1e-65
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...   249   1e-65
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...   248   2e-65
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...   247   4e-65

>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 2053 bits (5319), Expect = 0.0
 Identities = 1039/1039 (100%), Positives = 1039/1039 (100%)

Query: 1    MHQKTPEIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHK 60
            MHQKTPEIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHK
Sbjct: 1    MHQKTPEIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHK 60

Query: 61   LSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLW 120
            LSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLW
Sbjct: 61   LSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLW 120

Query: 121  VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI 180
            VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI
Sbjct: 121  VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI 180

Query: 181  PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ 240
            PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ
Sbjct: 181  PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ 240

Query: 241  PRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIA 300
            PRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIA
Sbjct: 241  PRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIA 300

Query: 301  IEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLS 360
            IEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLS
Sbjct: 301  IEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLS 360

Query: 361  LTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSED 420
            LTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSED
Sbjct: 361  LTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSED 420

Query: 421  HSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILG 480
            HSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILG
Sbjct: 421  HSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILG 480

Query: 481  DVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMING 540
            DVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMING
Sbjct: 481  DVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMING 540

Query: 541  EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCF 600
            EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCF
Sbjct: 541  EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCF 600

Query: 601  VGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIA 660
            VGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIA
Sbjct: 601  VGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIA 660

Query: 661  HRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC 720
            HRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC
Sbjct: 661  HRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC 720

Query: 721  QRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEG 780
            QRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEG
Sbjct: 721  QRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEG 780

Query: 781  RLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYE 840
            RLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYE
Sbjct: 781  RLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYE 840

Query: 841  KAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLIN 900
            KAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLIN
Sbjct: 841  KAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLIN 900

Query: 901  LRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIF 960
            LRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIF
Sbjct: 901  LRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIF 960

Query: 961  QQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEV 1020
            QQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEV
Sbjct: 961  QQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEV 1020

Query: 1021 RKLFIRLYPGSWWDKNMYY 1039
            RKLFIRLYPGSWWDKNMYY
Sbjct: 1021 RKLFIRLYPGSWWDKNMYY 1039


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score = 1330 bits (3442), Expect = 0.0
 Identities = 662/1027 (64%), Positives = 823/1027 (80%), Gaps = 17/1027 (1%)

Query: 24   KGDGKEKY-----------RGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGT 72
            KG G++KY           +G K      KK    +E +KE+ +DDHKLS  EL  KYGT
Sbjct: 3    KGVGRDKYEPAAVSEQGDKKGKKG-----KKDRDMDELKKEVSMDDHKLSLDELHRKYGT 57

Query: 73   DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132
            D+  GL+S RAAE+LARDGPN+LTPP  TPE +KF +Q+ GGFS+LLW+GA LC++AY I
Sbjct: 58   DLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSI 117

Query: 133  QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
            Q ++++    +N+YLG VL  VVI+TG F+YYQEAKS+ IM SF  M+PQQALVIR+ EK
Sbjct: 118  QAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEK 177

Query: 193  KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252
             +I +E++VVGD+VEVKGGD+IPAD+R++S+ GC+VDNSSLTGESEPQ RS +FT+ENPL
Sbjct: 178  MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPL 237

Query: 253  ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAG 312
            ET+NI F+ST C+EGT  G+V+ TGDRT++G IA+LASG+   +TPIA EIEHF+HI+ G
Sbjct: 238  ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITG 297

Query: 313  VAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCL 372
            VAV +G+ FFI+++ L+Y  L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCL
Sbjct: 298  VAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCL 357

Query: 373  VKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRT 432
            VKNLEAVETLGSTS ICSDKTGTLTQNRMTVAH+WFDNQI  ADT+E+ S   FD++S T
Sbjct: 358  VKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSAT 417

Query: 433  WASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKV 492
            W +LS+I  LCNRA F+  QEN+PI+K+AV GDASE+ALLK  E+  G V E+R+R  K+
Sbjct: 418  WLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKI 477

Query: 493  AEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKT 552
             EIPFNSTNK+QLSIH+  +    + L+VMKGAPERIL++CS+I+++G+E PLD+     
Sbjct: 478  VEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDA 537

Query: 553  FHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRS 612
            F  AY+ELGGLGERVLGFCHL+LP ++FPE + FD D +NFP  NLCFVGL+SMIDPPR+
Sbjct: 538  FQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRA 597

Query: 613  TVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNK 672
             VPDAV KCRSAGIKVIMVTGDHPITAKAIAK VGIIS  +ETVEDIA RLNI V QVN 
Sbjct: 598  AVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNP 657

Query: 673  RDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGD 732
            RDAKA VV G +LKDM+SEQLD+IL  + EIVFARTSPQQKLIIVEGCQRQ A+VAVTGD
Sbjct: 658  RDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGD 717

Query: 733  GVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIA 792
            GVNDSPALKKADIG+AMGIAGSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IA
Sbjct: 718  GVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIA 777

Query: 793  YSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPR 852
            Y+LT NI E+ PFLI+II  +PLP+GT+TIL IDLGTD++P+I+LAYE+AESDIM R+PR
Sbjct: 778  YTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPR 837

Query: 853  HKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVND 912
            +   D+LVN+ L   +Y  IG++QALG F  YF + A+ GFLP  L+ LRV+W+  ++ND
Sbjct: 838  NPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWIND 897

Query: 913  LKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWV 972
            ++DSYGQ+WT  QR+ +E+T +TAFFV I+V Q ADL+I KTRRNS+FQQG+ +NK++  
Sbjct: 898  VEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGM-KNKILIF 956

Query: 973  GITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSW 1032
            G+  +  +   LSY  G   AL    L+  +WF A P+++LI+VYDEVRKL IR  PG W
Sbjct: 957  GLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGW 1016

Query: 1033 WDKNMYY 1039
             +K  YY
Sbjct: 1017 VEKETYY 1023


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 1330 bits (3441), Expect = 0.0
 Identities = 664/1033 (64%), Positives = 808/1033 (78%), Gaps = 5/1033 (0%)

Query: 7    EIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNREL 66
            E+YSVEL          K   K+K  G        K+K   E  +KE+ ++DH+LS  EL
Sbjct: 8    ELYSVELGPGPGGDMAAKMSKKKKAGGGGG-----KRKEKLENMKKEMEINDHQLSVAEL 62

Query: 67   EEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLC 126
            E+KY T    GLS++ AAELL RDGPN+L PP+ TPE VKF +Q+ GG   L+WV A +C
Sbjct: 63   EQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAIC 122

Query: 127  WIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALV 186
             IA+ IQ S     + +N+YL   L  VV++TG F YYQE KSTNI++SF  ++PQQA V
Sbjct: 123  LIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATV 182

Query: 187  IRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEF 246
            IRD +K  I ++QLVVGD+VE+KGGD++PADIR+L++QGC+VDNSSLTGESEPQ RS E 
Sbjct: 183  IRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPEC 242

Query: 247  THENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHF 306
            THE+PLET+NI F+ST CLEGTV G+V+NTGDRTIIG IASLASGV NEKTPIAIEIEHF
Sbjct: 243  THESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHF 302

Query: 307  VHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRM 366
            V I+AG+A+  G  FFI+A+ + Y  L +++F + I+VA VPEGLLATVTV LSLTAKR+
Sbjct: 303  VDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRL 362

Query: 367  AKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVF 426
            A KNC+VKNLEAVETLGSTS+ICSDKTGTLTQNRMTV+HLWFDN I  ADT+ED S Q F
Sbjct: 363  ASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTF 422

Query: 427  DQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIR 486
            DQSS TW +L +++TLCNRA FK GQ+ VP+ K+ VIGDASETALLKFSE+ LG+ M  R
Sbjct: 423  DQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYR 482

Query: 487  KRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLD 546
             R  KV EIPFNSTNKFQLSIH ++DP   R L+VMKGAPER+LE+CS+I+I G+E PLD
Sbjct: 483  DRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLD 542

Query: 547  KSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSM 606
            +   + F TAY+ LGGLGERVLGFC LYL   ++P  Y+FD++AMNFP+S LCF GL+SM
Sbjct: 543  EQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSM 602

Query: 607  IDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIA 666
            IDPPR+TVPDAV KCR+AGI+VIMVTGDHPITAKAIA SVGIIS  SETVEDIA RL + 
Sbjct: 603  IDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVP 662

Query: 667  VEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAV 726
            V+QVN++DA+A V+ GM+LKDM   +L E L  + E+VFARTSPQQKL+IVE CQR  A+
Sbjct: 663  VDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAI 722

Query: 727  VAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDN 786
            VAVTGDGVNDSPALKKADIG+AMGIAGSDAAKNAADM+LLDDNFASIVTGVE+GRLIFDN
Sbjct: 723  VAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDN 782

Query: 787  LKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDI 846
            LKK+IAY+LTKNI EL P+LIYI V +PLP+G ITILFI+L TDI PS++LAYEKAESDI
Sbjct: 783  LKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDI 842

Query: 847  MNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWE 906
            M+ +PR+  +DRLVN+PLA YSY  IG +Q+   F  YFT  AQEG+ P   + LR +WE
Sbjct: 843  MHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE 902

Query: 907  KDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFR 966
              ++ DL+DSYGQEWT  QR Y ++T YT FF+ I V QIAD++IRKTRR S FQQG FR
Sbjct: 903  DHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFR 962

Query: 967  NKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIR 1026
            NK++ + I  Q+ IG  L Y  G     +F  +R Q+W V +P+ ILI+VYDE+RKL +R
Sbjct: 963  NKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVR 1022

Query: 1027 LYPGSWWDKNMYY 1039
              PGSWWD+ +YY
Sbjct: 1023 CCPGSWWDQELYY 1035


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score = 1329 bits (3439), Expect = 0.0
 Identities = 655/998 (65%), Positives = 813/998 (81%), Gaps = 1/998 (0%)

Query: 42   KKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQT 101
            KK    +E +KE+ +DDHKLS  EL  KYGTD+  GL+S RAAE+LARDGPN+LTPP  T
Sbjct: 27   KKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTT 86

Query: 102  PEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIF 161
            PE +KF +Q+ GGFS+LLW+GA LC++AY IQ ++++    +N+YLG VL  VVI+TG F
Sbjct: 87   PEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCF 146

Query: 162  AYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVL 221
            +YYQEAKS+ IM SF  M+PQQALVIR+ EK +I +E++VVGD+VEVKGGD+IPAD+R++
Sbjct: 147  SYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRII 206

Query: 222  SSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTI 281
            S+ GC+VDNSSLTGESEPQ RS +FT+ENPLET+NI F+ST C+EGT  G+V+ TGDRT+
Sbjct: 207  SANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTV 266

Query: 282  IGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIG 341
            +G IA+LASG+   +TPIA EIEHF+HI+ GVAV +G+ FFI+++ L+Y  L+++IFLIG
Sbjct: 267  MGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIG 326

Query: 342  IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
            IIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETLGSTS ICSDKTGTLTQNRM
Sbjct: 327  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 386

Query: 402  TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKA 461
            TVAH+WFDNQI  ADT+E+ S   FD++S TW +LS+I  LCNRA F+  QEN+PI+K+A
Sbjct: 387  TVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRA 446

Query: 462  VIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMV 521
            V GDASE+ALLK  E+  G V E+R+R  K+ EIPFNSTNK+QLSIH+  +    + L+V
Sbjct: 447  VAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLV 506

Query: 522  MKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFP 581
            MKGAPERIL++CS+I+++G+E PLD+     F  AY+ELGGLGERVLGFCHL+LP ++FP
Sbjct: 507  MKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFP 566

Query: 582  ETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKA 641
            E + FD D +NFP  NLCFVGL+SMIDPPR+ VPDAV KCRSAGIKVIMVTGDHPITAKA
Sbjct: 567  EGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 626

Query: 642  IAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQ 701
            IAK VGIIS  +ETVEDIA RLNI V QVN RDAKA VV G +LKDM+SEQLD+IL  + 
Sbjct: 627  IAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHT 686

Query: 702  EIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAA 761
            EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKKADIG+AMGIAGSD +K AA
Sbjct: 687  EIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAA 746

Query: 762  DMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTIT 821
            DM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+ PFLI+II  +PLP+GT+T
Sbjct: 747  DMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVT 806

Query: 822  ILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAF 881
            IL IDLGTD++P+I+LAYE+AESDIM R+PR+   D+LVN+ L   +Y  IG++QALG F
Sbjct: 807  ILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGF 866

Query: 882  LVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGI 941
              YF + A+ GFLP  L+ LRV+W+  ++ND++DSYGQ+WT  QR+ +E+T +TAFFV I
Sbjct: 867  FTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSI 926

Query: 942  LVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRA 1001
            +V Q ADL+I KTRRNS+FQQG+ +NK++  G+  +  +   LSY  G   AL    L+ 
Sbjct: 927  VVVQWADLVICKTRRNSVFQQGM-KNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKP 985

Query: 1002 QYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
             +WF A P+++LI+VYDEVRKL IR  PG W +K  YY
Sbjct: 986  TWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 1328 bits (3436), Expect = 0.0
 Identities = 654/1019 (64%), Positives = 816/1019 (80%), Gaps = 9/1019 (0%)

Query: 21   KTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSS 80
            K D  D  +K +G        K++   ++ +KE+ + +HK+S  E+  KY TD + GL+ 
Sbjct: 4    KKDDKDSPKKNKG--------KERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTH 55

Query: 81   TRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSA 140
            ++A E+LARDGPN+LTPP  TPE VKF +Q+ GGFSILLW+GA LC++AYGIQ  ++   
Sbjct: 56   SKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDP 115

Query: 141  SLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQL 200
            S +N+YLG VL  VVI+TG F+YYQEAKS+ IM SF  M+PQQALVIR+ EK  + +E++
Sbjct: 116  SGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEV 175

Query: 201  VVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFY 260
            VVGD+VE+KGGD++PAD+R++S+ GC+VDNSSLTGESEPQ RS + TH+NPLET+NI F+
Sbjct: 176  VVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFF 235

Query: 261  STTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGIL 320
            ST C+EGT  G+V+ TGDRT++G IA+LASG+   KTPIAIEIEHF+ ++ GVAV +G+ 
Sbjct: 236  STNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVS 295

Query: 321  FFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVE 380
            FFI+++ L Y  L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVE
Sbjct: 296  FFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVE 355

Query: 381  TLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKII 440
            TLGSTS ICSDKTGTLTQNRMTVAH+WFDNQI  ADT+ED S   FD+SS TW +LS I 
Sbjct: 356  TLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIA 415

Query: 441  TLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNST 500
             LCNRA FK GQ+N+P++K+ V GDASE+ALLK  E+  G V  +R+RN+KVAEIPFNST
Sbjct: 416  GLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNST 475

Query: 501  NKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
            NK+QLSIHE +DP+  R+L+VMKGAPERIL++CSTI++ G+E PLD+   + F  AY+EL
Sbjct: 476  NKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLEL 535

Query: 561  GGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTK 620
            GGLGERVLGFCH YLP ++FP+ ++FD D +NF T NLCFVGL+SMIDPPR+ VPDAV K
Sbjct: 536  GGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGK 595

Query: 621  CRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVV 680
            CRSAGIKVIMVTGDHPITAKAIAK VGIIS  +ETVEDIA RLNI V QVN RDAKA V+
Sbjct: 596  CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVI 655

Query: 681  TGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPAL 740
             G +LKD +SEQ+DEIL N+ EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPAL
Sbjct: 656  HGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPAL 715

Query: 741  KKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIA 800
            KKADIG+AMGIAGSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI 
Sbjct: 716  KKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 775

Query: 801  ELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLV 860
            E+ PFL++I+  +PLP+GTITIL IDLGTD++P+I+LAYE AESDIM R+PR+   D+LV
Sbjct: 776  EITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLV 835

Query: 861  NQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQE 920
            N+ L   +Y  IG++QALG F  YF + A+ GFLP  L+ +R+ W+   VNDL+DSYGQ+
Sbjct: 836  NERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQ 895

Query: 921  WTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIII 980
            WT  QR+ +E+T +TAFFV I+V Q ADLII KTRRNS+FQQG+ +NK++  G+  +  +
Sbjct: 896  WTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLFEETAL 954

Query: 981  GLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
               LSY  G   AL    L+  +WF A P++ LI+VYDE+RKL +R  PG W +K  YY
Sbjct: 955  AAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
          Length = 992

 Score = 1326 bits (3432), Expect = 0.0
 Identities = 653/992 (65%), Positives = 811/992 (81%), Gaps = 1/992 (0%)

Query: 48   EEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKF 107
            +E +KE+ +DDHKLS  EL  KYGTD+  GL+S RAAE+LARDGPN+LTPP  TPE +KF
Sbjct: 2    DELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKF 61

Query: 108  LKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEA 167
             +Q+ GGFS+LLW+GA LC++AY IQ ++++    +N+YLG VL  VVI+TG F+YYQEA
Sbjct: 62   CRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 121

Query: 168  KSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCR 227
            KS+ IM SF  M+PQQALVIR+ EK +I +E++VVGD+VEVKGGD+IPAD+R++S+ GC+
Sbjct: 122  KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCK 181

Query: 228  VDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIAS 287
            VDNSSLTGESEPQ RS +FT+ENPLET+NI F+ST C+EGT  G+V+ TGDRT++G IA+
Sbjct: 182  VDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIAT 241

Query: 288  LASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANV 347
            LASG+   +TPIA EIEHF+HI+ GVAV +G+ FFI+++ L+Y  L+++IFLIGIIVANV
Sbjct: 242  LASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANV 301

Query: 348  PEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLW 407
            PEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETLGSTS ICSDKTGTLTQNRMTVAH+W
Sbjct: 302  PEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW 361

Query: 408  FDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDAS 467
            FDNQI  ADT+E+ S   FD++S TW +LS+I  LCNRA F+  QEN+PI+K+AV GDAS
Sbjct: 362  FDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDAS 421

Query: 468  ETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPE 527
            E+ALLK  E+  G V E+R+R  K+ EIPFNSTNK+QLSIH+  +    + L+VMKGAPE
Sbjct: 422  ESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPE 481

Query: 528  RILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFD 587
            RIL++CS+I+++G+E PLD+     F  AY+ELGGLGERVLGFCHL+LP ++FPE + FD
Sbjct: 482  RILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFD 541

Query: 588  IDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVG 647
             D +NFP  NLCFVGL+SMIDPPR+ VPDAV KCRSAGIKVIMVTGDHPITAKAIAK VG
Sbjct: 542  TDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG 601

Query: 648  IISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFAR 707
            IIS  +ETVEDIA RLNI V QVN RDAKA VV G +LKDM+SEQLD+IL  + EIVFAR
Sbjct: 602  IISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFAR 661

Query: 708  TSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLD 767
            TSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKKADIG+AMGIAGSD +K AADM+LLD
Sbjct: 662  TSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLD 721

Query: 768  DNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDL 827
            DNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+ PFLI+II  +PLP+GT+TIL IDL
Sbjct: 722  DNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDL 781

Query: 828  GTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTV 887
            GTD++P+I+LAYE+AESDIM R+PR+   D+LVN+ L   +Y  IG++QALG F  YF +
Sbjct: 782  GTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVI 841

Query: 888  YAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIA 947
             A+ GFLP  L+ LRV+W+  ++ND++DSYGQ+WT  QR+ +E+T +TAFFV I+V Q A
Sbjct: 842  LAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWA 901

Query: 948  DLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVA 1007
            DL+I KTRRNS+FQQG+ +NK++  G+  +  +   LSY  G   AL    L+  +WF A
Sbjct: 902  DLVICKTRRNSVFQQGM-KNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960

Query: 1008 VPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
             P+++LI+VYDEVRKL IR  PG W +K  YY
Sbjct: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 1321 bits (3420), Expect = 0.0
 Identities = 659/1017 (64%), Positives = 809/1017 (79%), Gaps = 13/1017 (1%)

Query: 23   DKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTR 82
            + G GK+K           +K+   +E +KE+ +DDHKLS  EL  KY  D+  GL++ R
Sbjct: 17   ENGGGKKK-----------QKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQR 65

Query: 83   AAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASL 142
            A ++LARDGPN+LTPP  TPE VKF +Q+ GGFSILLW+GA LC++AYGIQ + +   S 
Sbjct: 66   AQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSN 125

Query: 143  NNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVV 202
            +N+YLG VL  VVI+TG F+YYQEAKS+ IM SF  M+PQQALVIR+ EK  I +E++VV
Sbjct: 126  DNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVV 185

Query: 203  GDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYST 262
            GD+VEVKGGD++PAD+R++SS GC+VDNSSLTGESEPQ RS EFTHENPLET+NICF+ST
Sbjct: 186  GDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFST 245

Query: 263  TCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFF 322
             C+EGT  G+VI TGDRT++G IA+LASG+   +TPIA+EIEHF+ ++ GVAV +G+ FF
Sbjct: 246  NCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFF 305

Query: 323  IIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETL 382
            ++++ L Y  L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETL
Sbjct: 306  VLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETL 365

Query: 383  GSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITL 442
            GSTS ICSDKTGTLTQNRMTVAH+WFDNQI  ADT+ED S   FD+ S TW +LS+I  L
Sbjct: 366  GSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGL 425

Query: 443  CNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNK 502
            CNRA FK GQEN+ + K+   GDASE+ALLK  E+  G V ++R RN KVAEIPFNSTNK
Sbjct: 426  CNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNK 485

Query: 503  FQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGG 562
            +QLSIHE +D   +  ++VMKGAPERIL++CSTI++ G+E PLDK     F  AYMELGG
Sbjct: 486  YQLSIHEREDSP-QSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGG 544

Query: 563  LGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCR 622
            LGERVLGFC L LP+ +FP  + FD D +NFPT  LCFVGL+SMIDPPR+ VPDAV KCR
Sbjct: 545  LGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCR 604

Query: 623  SAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTG 682
            SAGIKVIMVTGDHPITAKAIAK VGIIS  +ETVEDIA RLNI + QVN R+AKA VV G
Sbjct: 605  SAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHG 664

Query: 683  MELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKK 742
             +LKDM+SEQLDEIL N+ EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKK
Sbjct: 665  SDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKK 724

Query: 743  ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802
            ADIGIAMGI+GSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+
Sbjct: 725  ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI 784

Query: 803  CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862
             PFL++II  +PLP+GT+TIL IDLGTD++P+I+LAYE AESDIM R+PR+   D+LVN+
Sbjct: 785  TPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNE 844

Query: 863  PLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWT 922
             L   +Y  IG++QALG F  YF + A+ GFLP  L+ +R++W+   +NDL+DSYGQEWT
Sbjct: 845  RLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWT 904

Query: 923  RYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGL 982
              QR+ +E+T +TAFF  I+V Q ADLII KTRRNS+FQQG+ +NK++  G+  +  +  
Sbjct: 905  YEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLLEETALAA 963

Query: 983  ILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
             LSY  G   AL    L+  +WF A P+++LI++YDEVRKL +R YPG W +K  YY
Sbjct: 964  FLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score = 1249 bits (3233), Expect = 0.0
 Identities = 628/998 (62%), Positives = 779/998 (78%), Gaps = 3/998 (0%)

Query: 42   KKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQT 101
            K+K + EE +KE+ +DDHKL+  EL  KY  D+  G S  RA E+L R GPN++TPP  T
Sbjct: 35   KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94

Query: 102  PEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIF 161
            PE VKF KQ+ GGFS+LLW GA LC++AY IQ   ++  + +N+YL  VL +VVI+TG F
Sbjct: 95   PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154

Query: 162  AYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVL 221
            +YYQEAKS+ IM SF  M+PQQALVIR  EK  I  +++V+GD+VE+KGGD++PAD+R++
Sbjct: 155  SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214

Query: 222  SSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTI 281
            S+QGC+VDNSSLTGESEPQ RS +FTHENPLET+NICF+ST C+EGT  G+VI TGD T+
Sbjct: 215  SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274

Query: 282  IGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIG 341
            +G IASL SG+   +TPIA EIEHF+H++  VAV +G+ FF +++ L Y  L++IIFLIG
Sbjct: 275  MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334

Query: 342  IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
            IIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETLGSTS ICSDKTGTLTQNRM
Sbjct: 335  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394

Query: 402  TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKA 461
            TVAH+WFD  ++ ADT+E+ + + F +SS TW  L++I  LCNRA+FK  QE +PI K+A
Sbjct: 395  TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454

Query: 462  VIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMV 521
              GDASE+ALLKF E     V E+R++N KVAEIPFNSTNK+Q+SIH  +D      LM 
Sbjct: 455  TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLM- 513

Query: 522  MKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFP 581
            MKGAPERILE CST ++NG+E+ ++    + F  AY+ELGGLGERVLGFC L LP+  F 
Sbjct: 514  MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-SFS 572

Query: 582  ETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKA 641
            + + F+ D +NFP  NLCFVGL+SMIDPPR+ VPDAV+KCRSAGIKVIMVTGDHPITAKA
Sbjct: 573  KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632

Query: 642  IAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQ 701
            IAK VGIIS  +ET E++A RL I + +V+   AKA VV G ELKD+ S+QLD+IL N+ 
Sbjct: 633  IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692

Query: 702  EIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAA 761
            EIVFARTSPQQKLIIVEGCQR  AVVAVTGDGVNDSPALKKADIGIAMGI+GSD +K AA
Sbjct: 693  EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752

Query: 762  DMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTIT 821
            DM+LLDDNFASIVTGVEEGRLIFDNLKK+I Y+LT NI E+ PFL++II+G+PLP+GTIT
Sbjct: 753  DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812

Query: 822  ILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAF 881
            IL IDLGTD++P+I+LAYE AESDIM R PR+   D LVN  L   +Y  IG++QAL  F
Sbjct: 813  ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872

Query: 882  LVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGI 941
              YF + A+ GF P  L+ +R+ WE  Y+NDL+DSYGQ+WT  QR+ +E+T  TAFFV I
Sbjct: 873  FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932

Query: 942  LVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRA 1001
            +V Q ADLII KTRRNS+FQQG+ RNKV+  GI  + ++   LSY  G   AL    L+ 
Sbjct: 933  VVVQWADLIISKTRRNSLFQQGM-RNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKI 991

Query: 1002 QYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039
             +W  A+P++ILI+VYDE+RKL IR +P  W ++  YY
Sbjct: 992  TWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  347 bits (889), Expect = 4e-95
 Identities = 276/878 (31%), Positives = 432/878 (49%), Gaps = 100/878 (11%)

Query: 77  GLSSTRAAELLARDGPNSLTPP--KQTPEIV--KFLKQMVGGFSILLWVGAFLCWIAYGI 132
           GLS  +      R GPN L     K   E+V  +F   +V    +   V   L W   G 
Sbjct: 23  GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
           + ++     L       V+ L+++   I   +QE  + + + +  +  P+   VIR   K
Sbjct: 83  ETTTAFVEPL-------VIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRK 135

Query: 193 --KTIPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLTGESEPQPRSSEFTH 248
             + I +  +V GDIVEV  GD++PAD+R++   S   RVD S LTGES    + +E   
Sbjct: 136 GVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIP 195

Query: 249 ENPL---ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
           +      + KN+ F  T    G   G+ + TG  T +G I S  + V  E+TP+  +++ 
Sbjct: 196 DPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDE 255

Query: 306 F----VHIVAGVAVSIGIL---FFIIAVSLKYQVLDSIIFL---IGIIVANVPEGLLATV 355
           F     H ++ + V++ ++    F         +  ++ +    + + VA +PEGL A +
Sbjct: 256 FGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVI 315

Query: 356 TVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFD------ 409
           T  L+L  +RMA+KN +V++L +VETLG TS+ICSDKTGTLT N+M+V  ++        
Sbjct: 316 TTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAG 375

Query: 410 ----NQIFVADTSEDHSNQVF--DQSSRTW-----ASLSKIITLCNRAEFKPGQENVPIM 458
               ++  ++ T+     +V   DQ  R         L+ I  LCN +     +      
Sbjct: 376 SCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYE 435

Query: 459 KKAVIGDASETALLKFSE---VILGDVME-------------IRKRNRKVAEIPFNSTNK 502
           K   +G+A+ETAL    E   V   D+               I++  RK   + F+   K
Sbjct: 436 K---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRK 492

Query: 503 FQLSIHEMDDPH--GKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
                     PH  G+   M +KGAPE ++E+CS++ +     PL  ++ +       + 
Sbjct: 493 SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDW 552

Query: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTSNLCFVGLLSMIDPPRSTVPD 616
           G   + +   C      D  P     ++D     + + T +L FVG + M+DPPR  V  
Sbjct: 553 GSGSDTLR--CLALATRDAPPRKEDMELDDCSKFVQYET-DLTFVGCVGMLDPPRPEVAA 609

Query: 617 AVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAK 676
            +T+C  AGI+V+M+TGD+  TA AI + +GI        ED+A +              
Sbjct: 610 CITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG----DTEDVAGK-------------- 651

Query: 677 AAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVND 736
               TG E  D+S EQ  +     +   FAR  P  K  IVE  Q  + + A+TGDGVND
Sbjct: 652 --AYTGREFDDLSPEQQRQACRTAR--CFARVEPAHKSRIVENLQSFNEITAMTGDGVND 707

Query: 737 SPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLT 796
           +PALKKA+IGIAMG +G+  AK+AA+MVL DDNFASIV  VEEGR I+ N+K+ I Y ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLIS 766

Query: 797 KNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
            N+ E+    +  I+GLP  +  + +L+++L TD +P+ AL +   + DIM + PR   +
Sbjct: 767 SNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPR-SPR 825

Query: 857 DRLVNQPLAVYSYLHIGLMQALG--AFLVYFTVYAQEG 892
           + L++  L  + YL IG+   L   A   ++ VY  EG
Sbjct: 826 EALISGWL-FFRYLAIGVYVGLATVAAATWWFVYDAEG 862


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  338 bits (866), Expect = 2e-92
 Identities = 266/878 (30%), Positives = 427/878 (48%), Gaps = 105/878 (11%)

Query: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118
           H  +  E+   +G +   GLS  +  +L  R G N L P ++   +++ + +      +L
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFE--DLL 61

Query: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178
           + +      I++ + +  +   ++       V+ L+++   I   +QE  + N + +  +
Sbjct: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKE 121

Query: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234
             P+   V R   K    I ++ +V GDIVE+  GD++PADIR+ S  S   RVD S LT
Sbjct: 122 YEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILT 181

Query: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286
           GES      S   H +P+        + KN+ F  T    G   G+V+ TG  T IG I 
Sbjct: 182 GESV-----SVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIR 236

Query: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGII--- 343
                   E+TP+  +++ F   ++ V   I I  +II +      +    ++ G I   
Sbjct: 237 DEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYF 296

Query: 344 -------VANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396
                  VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356

Query: 397 TQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWA---------------------S 435
           T N+M+V  ++  +++      +  S   F  +  T+A                      
Sbjct: 357 TTNQMSVCRMFILDRV----EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVE 412

Query: 436 LSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVI------LGDVMEIRKRN 489
           L+ I  LCN +     +      K   +G+A+ETAL    E +      L  + +I + N
Sbjct: 413 LATICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERAN 469

Query: 490 ----------RKVAEIPFNSTNKFQLSIHEMDDPHGKRFL--MVMKGAPERILEKCSTIM 537
                     +K   + F+   K  +S++   +   +  +  M +KGAPE ++++C+ I 
Sbjct: 470 ACNSVIKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR 528

Query: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPT-- 595
           +   + P+     +   +   E G  G   L    L    +          D+ NF    
Sbjct: 529 VGSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYE 587

Query: 596 SNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSET 655
           +NL FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI   +   
Sbjct: 588 TNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE-- 645

Query: 656 VEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLI 715
                             D  +   TG E  +++     +   N +   FAR  P  K  
Sbjct: 646 ------------------DVTSKAFTGREFDELNPSAQRDACLNAR--CFARVEPSHKSK 685

Query: 716 IVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVT 775
           IVE  Q  D + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV 
Sbjct: 686 IVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVA 744

Query: 776 GVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSI 835
            VEEGR I++N+K+ I Y ++ N+ E+    +   +G P  +  + +L+++L TD +P+ 
Sbjct: 745 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPAT 804

Query: 836 ALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG 873
           AL +   + DIMN+ PR+  K+ L++  L  + YL IG
Sbjct: 805 ALGFNPPDLDIMNKPPRNP-KEPLISGWL-FFRYLAIG 840


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
           [Homo sapiens]
          Length = 1042

 Score =  338 bits (866), Expect = 2e-92
 Identities = 266/878 (30%), Positives = 427/878 (48%), Gaps = 105/878 (11%)

Query: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118
           H  +  E+   +G +   GLS  +  +L  R G N L P ++   +++ + +      +L
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFE--DLL 61

Query: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178
           + +      I++ + +  +   ++       V+ L+++   I   +QE  + N + +  +
Sbjct: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKE 121

Query: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234
             P+   V R   K    I ++ +V GDIVE+  GD++PADIR+ S  S   RVD S LT
Sbjct: 122 YEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILT 181

Query: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286
           GES      S   H +P+        + KN+ F  T    G   G+V+ TG  T IG I 
Sbjct: 182 GESV-----SVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIR 236

Query: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGII--- 343
                   E+TP+  +++ F   ++ V   I I  +II +      +    ++ G I   
Sbjct: 237 DEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYF 296

Query: 344 -------VANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396
                  VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356

Query: 397 TQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWA---------------------S 435
           T N+M+V  ++  +++      +  S   F  +  T+A                      
Sbjct: 357 TTNQMSVCRMFILDRV----EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVE 412

Query: 436 LSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVI------LGDVMEIRKRN 489
           L+ I  LCN +     +      K   +G+A+ETAL    E +      L  + +I + N
Sbjct: 413 LATICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERAN 469

Query: 490 ----------RKVAEIPFNSTNKFQLSIHEMDDPHGKRFL--MVMKGAPERILEKCSTIM 537
                     +K   + F+   K  +S++   +   +  +  M +KGAPE ++++C+ I 
Sbjct: 470 ACNSVIKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR 528

Query: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPT-- 595
           +   + P+     +   +   E G  G   L    L    +          D+ NF    
Sbjct: 529 VGSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYE 587

Query: 596 SNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSET 655
           +NL FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI   +   
Sbjct: 588 TNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE-- 645

Query: 656 VEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLI 715
                             D  +   TG E  +++     +   N +   FAR  P  K  
Sbjct: 646 ------------------DVTSKAFTGREFDELNPSAQRDACLNAR--CFARVEPSHKSK 685

Query: 716 IVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVT 775
           IVE  Q  D + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV 
Sbjct: 686 IVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVA 744

Query: 776 GVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSI 835
            VEEGR I++N+K+ I Y ++ N+ E+    +   +G P  +  + +L+++L TD +P+ 
Sbjct: 745 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPAT 804

Query: 836 ALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG 873
           AL +   + DIMN+ PR+  K+ L++  L  + YL IG
Sbjct: 805 ALGFNPPDLDIMNKPPRNP-KEPLISGWL-FFRYLAIG 840


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score =  333 bits (855), Expect = 4e-91
 Identities = 273/898 (30%), Positives = 431/898 (47%), Gaps = 104/898 (11%)

Query: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118
           H  +  E    +G     GL+  +    L + G N L P ++   + + + +      +L
Sbjct: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNEL-PAEEGKTLWELVIEQFE--DLL 61

Query: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178
           + +      I++ + +  +   ++       V+ L++I   I   +QE  + N + +  +
Sbjct: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121

Query: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234
             P+   V R   K    I +  +V GDIVEV  GD++PADIR+L+  S   RVD S LT
Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286
           GES      S   H  P+        + KN+ F  T    G   G+V  TG  T IG I 
Sbjct: 182 GESV-----SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIR 236

Query: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAV----------SLKYQVLDSI 336
              +    +KTP+  +++ F   ++ V   I +  ++I +          S     +   
Sbjct: 237 DQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYF 296

Query: 337 IFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396
              + + VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356

Query: 397 TQNRMTVAHLWFD----------NQIFVADTSEDHSNQVFDQSSRT-------WASLSKI 439
           T N+M+V  ++            N+  +  ++     +V                 L+ I
Sbjct: 357 TTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATI 416

Query: 440 ITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE---VILGDVMEIRKRNR------ 490
             LCN +     +      K   +G+A+ETAL    E   V   DV  + K  R      
Sbjct: 417 CALCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNS 473

Query: 491 -------KVAEIPFNSTNKFQLSIHEMDDPHGKRFL---MVMKGAPERILEKCSTIMING 540
                  K   + F+   K  +S++       +  +   M +KGAPE ++++C+ + +  
Sbjct: 474 VIRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532

Query: 541 EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTS 596
              PL     K    A ++  G G   L  C      D  P+     +D     + + T 
Sbjct: 533 TRVPLT-GPVKEKIMAVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYET- 589

Query: 597 NLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETV 656
           +L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI   N E V
Sbjct: 590 DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEE-V 648

Query: 657 EDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLII 716
            D A+                   TG E  D+   +  E  A  +   FAR  P  K  I
Sbjct: 649 ADRAY-------------------TGREFDDLPLAEQRE--ACRRACCFARVEPSHKSKI 687

Query: 717 VEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTG 776
           VE  Q  D + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV  
Sbjct: 688 VEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 746

Query: 777 VEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIA 836
           VEEGR I++N+K+ I Y ++ N+ E+    +   +GLP  +  + +L+++L TD +P+ A
Sbjct: 747 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATA 806

Query: 837 LAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG--LMQALGAFLVYFTVYAQEG 892
           L +   + DIM+R PR   K+ L++  L  + Y+ IG  +  A      ++ +YA++G
Sbjct: 807 LGFNPPDLDIMDRPPR-SPKEPLISGWL-FFRYMAIGGYVGAATVGAAAWWFLYAEDG 862


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score =  333 bits (855), Expect = 4e-91
 Identities = 273/898 (30%), Positives = 431/898 (47%), Gaps = 104/898 (11%)

Query: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118
           H  +  E    +G     GL+  +    L + G N L P ++   + + + +      +L
Sbjct: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNEL-PAEEGKTLWELVIEQFE--DLL 61

Query: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178
           + +      I++ + +  +   ++       V+ L++I   I   +QE  + N + +  +
Sbjct: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121

Query: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234
             P+   V R   K    I +  +V GDIVEV  GD++PADIR+L+  S   RVD S LT
Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286
           GES      S   H  P+        + KN+ F  T    G   G+V  TG  T IG I 
Sbjct: 182 GESV-----SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIR 236

Query: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAV----------SLKYQVLDSI 336
              +    +KTP+  +++ F   ++ V   I +  ++I +          S     +   
Sbjct: 237 DQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYF 296

Query: 337 IFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396
              + + VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356

Query: 397 TQNRMTVAHLWFD----------NQIFVADTSEDHSNQVFDQSSRT-------WASLSKI 439
           T N+M+V  ++            N+  +  ++     +V                 L+ I
Sbjct: 357 TTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATI 416

Query: 440 ITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE---VILGDVMEIRKRNR------ 490
             LCN +     +      K   +G+A+ETAL    E   V   DV  + K  R      
Sbjct: 417 CALCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNS 473

Query: 491 -------KVAEIPFNSTNKFQLSIHEMDDPHGKRFL---MVMKGAPERILEKCSTIMING 540
                  K   + F+   K  +S++       +  +   M +KGAPE ++++C+ + +  
Sbjct: 474 VIRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532

Query: 541 EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTS 596
              PL     K    A ++  G G   L  C      D  P+     +D     + + T 
Sbjct: 533 TRVPLT-GPVKEKIMAVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYET- 589

Query: 597 NLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETV 656
           +L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI   N E V
Sbjct: 590 DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEE-V 648

Query: 657 EDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLII 716
            D A+                   TG E  D+   +  E  A  +   FAR  P  K  I
Sbjct: 649 ADRAY-------------------TGREFDDLPLAEQRE--ACRRACCFARVEPSHKSKI 687

Query: 717 VEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTG 776
           VE  Q  D + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV  
Sbjct: 688 VEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 746

Query: 777 VEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIA 836
           VEEGR I++N+K+ I Y ++ N+ E+    +   +GLP  +  + +L+++L TD +P+ A
Sbjct: 747 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATA 806

Query: 837 LAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG--LMQALGAFLVYFTVYAQEG 892
           L +   + DIM+R PR   K+ L++  L  + Y+ IG  +  A      ++ +YA++G
Sbjct: 807 LGFNPPDLDIMDRPPR-SPKEPLISGWL-FFRYMAIGGYVGAATVGAAAWWFLYAEDG 862


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  326 bits (836), Expect = 6e-89
 Identities = 246/847 (29%), Positives = 408/847 (48%), Gaps = 104/847 (12%)

Query: 73  DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132
           D+  GL+    +   A  G N     +  P   K++ Q      +LL   A +  +    
Sbjct: 41  DLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVL---- 96

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
            +  D + S+        + +++++T   A+ QE +S   +   +K++P +   +R+ + 
Sbjct: 97  MHQFDDAVSIT-------VAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVREGKL 147

Query: 193 KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252
           +   +  LV GD V +  GD++PAD+R+  +    +D SSLTGE+ P    S+ T   P 
Sbjct: 148 EHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP---CSKVTAPQPA 204

Query: 253 ETK-------NICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
            T        NI F  T    G   G+VI TG+ +  G +  +       KTP+   ++ 
Sbjct: 205 ATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDL 264

Query: 306 FVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKR 365
               ++  +  I  +  ++   L   +L+     + + VA +PEGL   VTVTL+L   R
Sbjct: 265 LGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMR 324

Query: 366 MAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSN-- 423
           M KK  +VK L  VETLG  ++ICSDKTGTLT+N MTV H++  + +    T   ++   
Sbjct: 325 MVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG 384

Query: 424 QVFDQSSRTWA----SLSKIIT---LCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476
           +V             ++S+I+    +CN A          I    ++G  +E AL+  + 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV---------IRNNTLMGKPTEGALIALAM 435

Query: 477 VILGDVME---IRKRNRKVAEIPFNSTNKFQL--SIH--EMDDPHGKRFLMVMKGAPERI 529
            +  D ++   IRK     AE PF+S  K+     +H  + D P     +  MKGA E++
Sbjct: 436 KMGLDGLQQDYIRK-----AEYPFSSEQKWMAVKCVHRTQQDRPE----ICFMKGAYEQV 486

Query: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589
           ++ C+T    G+   L +     +      +G  G RVL            PE       
Sbjct: 487 IKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SGPEL------ 533

Query: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649
                   L F+GL+ +IDPPR+ V +AVT   ++G+ + M+TGD   TA AIA  +G+ 
Sbjct: 534 ------GQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLY 587

Query: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709
           S  S++V                        +G E+  M  +QL +I+      VF R S
Sbjct: 588 SKTSQSV------------------------SGEEIDAMDVQQLSQIVPKVA--VFYRAS 621

Query: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769
           P+ K+ I++  Q+  +VVA+TGDGVND+ ALK ADIG+AMG  G+D  K AADM+L+DD+
Sbjct: 622 PRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 681

Query: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829
           F +I++ +EEG+ I++N+K  + + L+ +IA L    +  ++  P P+  + IL+I++  
Sbjct: 682 FQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741

Query: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889
           D  P+ +L  E  + D++ RKP    KD ++ + L +   L   ++   G   V++    
Sbjct: 742 DGPPAQSLGVEPVDKDVI-RKPPRNWKDSILTKNL-ILKILVSSIIIVCGTLFVFWRELR 799

Query: 890 QEGFLPR 896
                PR
Sbjct: 800 DNVITPR 806


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  326 bits (836), Expect = 6e-89
 Identities = 246/847 (29%), Positives = 408/847 (48%), Gaps = 104/847 (12%)

Query: 73  DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132
           D+  GL+    +   A  G N     +  P   K++ Q      +LL   A +  +    
Sbjct: 41  DLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVL---- 96

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
            +  D + S+        + +++++T   A+ QE +S   +   +K++P +   +R+ + 
Sbjct: 97  MHQFDDAVSIT-------VAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVREGKL 147

Query: 193 KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252
           +   +  LV GD V +  GD++PAD+R+  +    +D SSLTGE+ P    S+ T   P 
Sbjct: 148 EHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP---CSKVTAPQPA 204

Query: 253 ETK-------NICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
            T        NI F  T    G   G+VI TG+ +  G +  +       KTP+   ++ 
Sbjct: 205 ATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDL 264

Query: 306 FVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKR 365
               ++  +  I  +  ++   L   +L+     + + VA +PEGL   VTVTL+L   R
Sbjct: 265 LGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMR 324

Query: 366 MAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSN-- 423
           M KK  +VK L  VETLG  ++ICSDKTGTLT+N MTV H++  + +    T   ++   
Sbjct: 325 MVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG 384

Query: 424 QVFDQSSRTWA----SLSKIIT---LCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476
           +V             ++S+I+    +CN A          I    ++G  +E AL+  + 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV---------IRNNTLMGKPTEGALIALAM 435

Query: 477 VILGDVME---IRKRNRKVAEIPFNSTNKFQL--SIH--EMDDPHGKRFLMVMKGAPERI 529
            +  D ++   IRK     AE PF+S  K+     +H  + D P     +  MKGA E++
Sbjct: 436 KMGLDGLQQDYIRK-----AEYPFSSEQKWMAVKCVHRTQQDRPE----ICFMKGAYEQV 486

Query: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589
           ++ C+T    G+   L +     +      +G  G RVL            PE       
Sbjct: 487 IKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SGPEL------ 533

Query: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649
                   L F+GL+ +IDPPR+ V +AVT   ++G+ + M+TGD   TA AIA  +G+ 
Sbjct: 534 ------GQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLY 587

Query: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709
           S  S++V                        +G E+  M  +QL +I+      VF R S
Sbjct: 588 SKTSQSV------------------------SGEEIDAMDVQQLSQIVPKVA--VFYRAS 621

Query: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769
           P+ K+ I++  Q+  +VVA+TGDGVND+ ALK ADIG+AMG  G+D  K AADM+L+DD+
Sbjct: 622 PRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 681

Query: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829
           F +I++ +EEG+ I++N+K  + + L+ +IA L    +  ++  P P+  + IL+I++  
Sbjct: 682 FQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741

Query: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889
           D  P+ +L  E  + D++ RKP    KD ++ + L +   L   ++   G   V++    
Sbjct: 742 DGPPAQSLGVEPVDKDVI-RKPPRNWKDSILTKNL-ILKILVSSIIIVCGTLFVFWRELR 799

Query: 890 QEGFLPR 896
                PR
Sbjct: 800 DNVITPR 806


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  326 bits (836), Expect = 6e-89
 Identities = 246/847 (29%), Positives = 408/847 (48%), Gaps = 104/847 (12%)

Query: 73  DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132
           D+  GL+    +   A  G N     +  P   K++ Q      +LL   A +  +    
Sbjct: 41  DLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVL---- 96

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
            +  D + S+        + +++++T   A+ QE +S   +   +K++P +   +R+ + 
Sbjct: 97  MHQFDDAVSIT-------VAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVREGKL 147

Query: 193 KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252
           +   +  LV GD V +  GD++PAD+R+  +    +D SSLTGE+ P    S+ T   P 
Sbjct: 148 EHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP---CSKVTAPQPA 204

Query: 253 ETK-------NICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
            T        NI F  T    G   G+VI TG+ +  G +  +       KTP+   ++ 
Sbjct: 205 ATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDL 264

Query: 306 FVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKR 365
               ++  +  I  +  ++   L   +L+     + + VA +PEGL   VTVTL+L   R
Sbjct: 265 LGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMR 324

Query: 366 MAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSN-- 423
           M KK  +VK L  VETLG  ++ICSDKTGTLT+N MTV H++  + +    T   ++   
Sbjct: 325 MVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG 384

Query: 424 QVFDQSSRTWA----SLSKIIT---LCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476
           +V             ++S+I+    +CN A          I    ++G  +E AL+  + 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV---------IRNNTLMGKPTEGALIALAM 435

Query: 477 VILGDVME---IRKRNRKVAEIPFNSTNKFQL--SIH--EMDDPHGKRFLMVMKGAPERI 529
            +  D ++   IRK     AE PF+S  K+     +H  + D P     +  MKGA E++
Sbjct: 436 KMGLDGLQQDYIRK-----AEYPFSSEQKWMAVKCVHRTQQDRPE----ICFMKGAYEQV 486

Query: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589
           ++ C+T    G+   L +     +      +G  G RVL            PE       
Sbjct: 487 IKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SGPEL------ 533

Query: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649
                   L F+GL+ +IDPPR+ V +AVT   ++G+ + M+TGD   TA AIA  +G+ 
Sbjct: 534 ------GQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLY 587

Query: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709
           S  S++V                        +G E+  M  +QL +I+      VF R S
Sbjct: 588 SKTSQSV------------------------SGEEIDAMDVQQLSQIVPKVA--VFYRAS 621

Query: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769
           P+ K+ I++  Q+  +VVA+TGDGVND+ ALK ADIG+AMG  G+D  K AADM+L+DD+
Sbjct: 622 PRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 681

Query: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829
           F +I++ +EEG+ I++N+K  + + L+ +IA L    +  ++  P P+  + IL+I++  
Sbjct: 682 FQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741

Query: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889
           D  P+ +L  E  + D++ RKP    KD ++ + L +   L   ++   G   V++    
Sbjct: 742 DGPPAQSLGVEPVDKDVI-RKPPRNWKDSILTKNL-ILKILVSSIIIVCGTLFVFWRELR 799

Query: 890 QEGFLPR 896
                PR
Sbjct: 800 DNVITPR 806


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  326 bits (836), Expect = 6e-89
 Identities = 246/847 (29%), Positives = 408/847 (48%), Gaps = 104/847 (12%)

Query: 73  DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132
           D+  GL+    +   A  G N     +  P   K++ Q      +LL   A +  +    
Sbjct: 41  DLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVL---- 96

Query: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192
            +  D + S+        + +++++T   A+ QE +S   +   +K++P +   +R+ + 
Sbjct: 97  MHQFDDAVSIT-------VAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVREGKL 147

Query: 193 KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252
           +   +  LV GD V +  GD++PAD+R+  +    +D SSLTGE+ P    S+ T   P 
Sbjct: 148 EHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP---CSKVTAPQPA 204

Query: 253 ETK-------NICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305
            T        NI F  T    G   G+VI TG+ +  G +  +       KTP+   ++ 
Sbjct: 205 ATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDL 264

Query: 306 FVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKR 365
               ++  +  I  +  ++   L   +L+     + + VA +PEGL   VTVTL+L   R
Sbjct: 265 LGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMR 324

Query: 366 MAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSN-- 423
           M KK  +VK L  VETLG  ++ICSDKTGTLT+N MTV H++  + +    T   ++   
Sbjct: 325 MVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG 384

Query: 424 QVFDQSSRTWA----SLSKIIT---LCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476
           +V             ++S+I+    +CN A          I    ++G  +E AL+  + 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV---------IRNNTLMGKPTEGALIALAM 435

Query: 477 VILGDVME---IRKRNRKVAEIPFNSTNKFQL--SIH--EMDDPHGKRFLMVMKGAPERI 529
            +  D ++   IRK     AE PF+S  K+     +H  + D P     +  MKGA E++
Sbjct: 436 KMGLDGLQQDYIRK-----AEYPFSSEQKWMAVKCVHRTQQDRPE----ICFMKGAYEQV 486

Query: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589
           ++ C+T    G+   L +     +      +G  G RVL            PE       
Sbjct: 487 IKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SGPEL------ 533

Query: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649
                   L F+GL+ +IDPPR+ V +AVT   ++G+ + M+TGD   TA AIA  +G+ 
Sbjct: 534 ------GQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLY 587

Query: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709
           S  S++V                        +G E+  M  +QL +I+      VF R S
Sbjct: 588 SKTSQSV------------------------SGEEIDAMDVQQLSQIVPKVA--VFYRAS 621

Query: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769
           P+ K+ I++  Q+  +VVA+TGDGVND+ ALK ADIG+AMG  G+D  K AADM+L+DD+
Sbjct: 622 PRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 681

Query: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829
           F +I++ +EEG+ I++N+K  + + L+ +IA L    +  ++  P P+  + IL+I++  
Sbjct: 682 FQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741

Query: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889
           D  P+ +L  E  + D++ RKP    KD ++ + L +   L   ++   G   V++    
Sbjct: 742 DGPPAQSLGVEPVDKDVI-RKPPRNWKDSILTKNL-ILKILVSSIIIVCGTLFVFWRELR 799

Query: 890 QEGFLPR 896
                PR
Sbjct: 800 DNVITPR 806


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  324 bits (831), Expect = 2e-88
 Identities = 254/848 (29%), Positives = 392/848 (46%), Gaps = 78/848 (9%)

Query: 60  KLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILL 119
           K    +L   +  D+  GLS     +     G N        P   K+L Q      ILL
Sbjct: 59  KCQKEDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPL-ILL 117

Query: 120 WVGAFLCWIAYGIQYSSDKSASLNNVYLGCV-LGLVVILTGIFAYYQEAKSTNIMSSFNK 178
            +G+ L  +             L   Y   V +   V++    A+ QE +S   +    K
Sbjct: 118 LLGSALVSV-------------LTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELTK 164

Query: 179 MIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESE 238
           M+P +   +R+ + + + + +LV GD+V +  GD+IPADIR+       VD SS TGE+E
Sbjct: 165 MVPPECNCLREGKLQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAE 224

Query: 239 PQPRS-SEFTHENPLET-KNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEK 296
           P  ++ S  T    L T  NI F  T    G   G+VI TG+ +  G +  +       K
Sbjct: 225 PCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPK 284

Query: 297 TPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVT 356
           TP+   ++     +   +  I  L  +I  S   Q+L      + + VA +PEGL   V 
Sbjct: 285 TPLQKSMDRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVM 344

Query: 357 VTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIF--V 414
           VTL L   RMAKK  +VK L  VETLG  S++CSDKTGTLT N MTV  L   + +   V
Sbjct: 345 VTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEV 404

Query: 415 ADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKF 474
           +    D    V    S+        +++    E      N  I K AV+G  +E AL+  
Sbjct: 405 SGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMAL 464

Query: 475 SEVILGDVMEIRKRNRKVAEIPFNSTNKFQ-----LSIHEMDDPHGKRFLMVMKGAPERI 529
           +  +  D+ +I+    +  EIPF+S  K+      L   + +D      +  MKGA E +
Sbjct: 465 AMKM--DLSDIKNSYIRKKEIPFSSEQKWMAVKCSLKTEDQED------IYFMKGALEEV 516

Query: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589
           +  C+     G   PL              +G LG RVL            PE       
Sbjct: 517 IRYCTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALA-------SGPEL------ 563

Query: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649
                   L F+GL+ +IDPPR  V +AV     +G+ V M+TGD   TA AI +++G+ 
Sbjct: 564 ------GRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLC 617

Query: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709
           +                         K   ++G E+  +   +L + +      VF RTS
Sbjct: 618 NG------------------------KLQAMSGEEVDSVEKGELADRVGKVS--VFFRTS 651

Query: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769
           P+ KL I++  Q   A+VA+TGDGVND+ ALK ADIGIAMG  G+D +K AA+M+L+DD+
Sbjct: 652 PKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDD 711

Query: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829
           F++I+  VEEG+ IF N+K  + + L+ +I+ L    +  +  LP P+  + IL+I++  
Sbjct: 712 FSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIM 771

Query: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889
           D  P+ +L  E  + D   + PR   +D ++++ L +   +   ++ +   F+ +  +  
Sbjct: 772 DGPPAQSLGVEPVDKDAFRQPPR-SVRDTILSRALILKILMSAAIIISGTLFIFWKEMPE 830

Query: 890 QEGFLPRT 897
                PRT
Sbjct: 831 DRASTPRT 838


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score =  308 bits (790), Expect = 1e-83
 Identities = 249/868 (28%), Positives = 410/868 (47%), Gaps = 112/868 (12%)

Query: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118
           H  +  E+   +G +   GLS  +  +L  R G N L P ++   +++ + +      +L
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFE--DLL 61

Query: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178
           + +      I++ + +  +   ++       V+ L+++   I   +QE  + N + +  +
Sbjct: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKE 121

Query: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGE 236
             P+   V R   K    I ++ +V GDIVE+ G                  ++ S+   
Sbjct: 122 YEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIKH 163

Query: 237 SEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEK 296
           ++P P       +     KN+ F  T    G   G+V+ TG  T IG I         E+
Sbjct: 164 TDPVPDPRAVNQDK----KNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQER 219

Query: 297 TPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGII----------VAN 346
           TP+  +++ F   ++ V   I I  +II +      +    ++ G I          VA 
Sbjct: 220 TPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAA 279

Query: 347 VPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHL 406
           +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTLT N+M+V  +
Sbjct: 280 IPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 339

Query: 407 WFDNQIFVADTSEDHSNQVFDQSSRTWA---------------------SLSKIITLCNR 445
           +  +++      +  S   F  +  T+A                      L+ I  LCN 
Sbjct: 340 FILDRV----EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 395

Query: 446 AEFKPGQENVPIMKKAVIGDASETALLKFSEVI------LGDVMEIRKRN---------- 489
           +     +      K   +G+A+ETAL    E +      L  + +I + N          
Sbjct: 396 SALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLM 452

Query: 490 RKVAEIPFNSTNKFQLSIHEMDDPHGKRFL--MVMKGAPERILEKCSTIMINGEEHPLDK 547
           +K   + F+   K  +S++   +   +  +  M +KGAPE ++++C+ I +   + P+  
Sbjct: 453 KKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTS 511

Query: 548 STAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPT--SNLCFVGLLS 605
              +   +   E G  G   L    L    +          D+ NF    +NL FVG + 
Sbjct: 512 GVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVG 570

Query: 606 MIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNI 665
           M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI   +             
Sbjct: 571 MLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE------------ 618

Query: 666 AVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDA 725
                   D  +   TG E  +++     +   N +   FAR  P  K  IVE  Q  D 
Sbjct: 619 --------DVTSKAFTGREFDELNPSAQRDACLNAR--CFARVEPSHKSKIVEFLQSFDE 668

Query: 726 VVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFD 785
           + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV  VEEGR I++
Sbjct: 669 ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 727

Query: 786 NLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESD 845
           N+K+ I Y ++ N+ E+    +   +G P  +  + +L+++L TD +P+ AL +   + D
Sbjct: 728 NMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 787

Query: 846 IMNRKPRHKNKDRLVNQPLAVYSYLHIG 873
           IMN+ PR+  K+ L++  L  + YL IG
Sbjct: 788 IMNKPPRNP-KEPLISGWL-FFRYLAIG 813


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  278 bits (710), Expect = 2e-74
 Identities = 238/784 (30%), Positives = 374/784 (47%), Gaps = 129/784 (16%)

Query: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213
           VV++T    + +E +   + S   +   Q+  V+R  +   IP  ++VVGDI +VK GD 
Sbjct: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221

Query: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273
           +PAD   +     ++D SSLTGES+   +S +   ++P+         T  +EG+   +V
Sbjct: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVMEGSGRMLV 273

Query: 274 INTGDRTIIGHIASLASGVGNEK------------------------------------- 296
              G  +  G I +L    G E+                                     
Sbjct: 274 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASM 333

Query: 297 ------------TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLK 329
                       T +A++I     +++ + V I +L+F +                V ++
Sbjct: 334 HKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQ 393

Query: 330 YQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIIC 389
           Y V   II +  ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + IC
Sbjct: 394 YFVKFFIIGVTVLVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452

Query: 390 SDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLC--NRA- 446
           SDKTGTLT NRMTV       Q +V D    H  ++ D SS    ++  +I     N A 
Sbjct: 453 SDKTGTLTTNRMTVV------QAYVGDV---HYKEIPDPSSINTKTMELLINAIAINSAY 503

Query: 447 --EFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKR--NRKVAEI-PFNSTN 501
             +  P ++   + ++  +G+ +E  LL F   +  D   +R +    K+ ++  FNS  
Sbjct: 504 TTKILPPEKEGALPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVR 561

Query: 502 KFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAY 557
           K   ++ ++ D   + F M  KGA E +L+KC  I+    E     P D+          
Sbjct: 562 KSMSTVIKLPD---ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEP 618

Query: 558 MELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDA 617
           M   GL       C  Y    +FP +   D D  N   + L  + ++ + DP R  VP+A
Sbjct: 619 MACDGLRT----ICVAYR---DFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEA 671

Query: 618 VTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKA 677
           + KC+ AGI V MVTGD+  TA+AIA   GII    +        L +  ++ N+R    
Sbjct: 672 IRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIRN- 723

Query: 678 AVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC-----QRQDAVVAVTGD 732
                 E  ++  E++D+I    +  V AR+SP  K  +V+G        Q  VVAVTGD
Sbjct: 724 ------EKGEIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD 775

Query: 733 GVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIA 792
           G ND PALKKAD+G AMGIAG+D AK A+D++L DDNF+SIV  V  GR ++D++ K + 
Sbjct: 776 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQ 835

Query: 793 YSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPR 852
           + LT N+  +        +    P+  + +L+++L  D   S+ALA E     ++ RKP 
Sbjct: 836 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPY 895

Query: 853 HKNK 856
            +NK
Sbjct: 896 GRNK 899


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
            sapiens]
          Length = 1176

 Score =  249 bits (635), Expect = 1e-65
 Identities = 224/755 (29%), Positives = 353/755 (46%), Gaps = 103/755 (13%)

Query: 297  TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLKYQVLDSIIFLIG 341
            T +A++I     +++ + V I +L+F+I                + ++Y V   II +  
Sbjct: 367  TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426

Query: 342  IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
            ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 427  LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485

Query: 402  TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIIT-----LCNRAEFKPGQENVP 456
            TV   + +         E H  +V +  +     LS ++T         ++  P ++   
Sbjct: 486  TVVQAYIN---------EKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536

Query: 457  IMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVA---EIPFNSTNKFQLSIHEMDDP 513
            + +   +G+ +E ALL     +  D  ++R    + A      FNS  K   ++ +  D 
Sbjct: 537  LPRH--VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDG 594

Query: 514  HGKRFLMVMKGAPERILEKCSTIM-INGEE---HPLDKSTAKTFHTAYMELGGLGERVLG 569
              + F    KGA E IL+KC  I+  NGE     P D+       T    +   G R + 
Sbjct: 595  SYRIF---SKGASEIILKKCFKILSANGEAKVFRPRDRDDI--VKTVIEPMASEGLRTIC 649

Query: 570  FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629
                  PA E PE    + D  N   + L  + ++ + DP R  VPDA+ KC+ AGI V 
Sbjct: 650  LAFRDFPAGE-PEP---EWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVR 705

Query: 630  MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689
            MVTGD+  TA+AIA   GI+    +        L +  +  N+R          E  ++ 
Sbjct: 706  MVTGDNINTARAIATKCGILHPGEDF-------LCLEGKDFNRRIRN-------EKGEIE 751

Query: 690  SEQLDEILANYQEIVFARTSPQQKLIIVEGC-------QRQDAVVAVTGDGVNDSPALKK 742
             E++D+I    +  V AR+SP  K  +V+G        QRQ  VVAVTGDG ND PALKK
Sbjct: 752  QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTNDGPALKK 807

Query: 743  ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802
            AD+G AMGIAG+D AK A+D++L DDNF SIV  V  GR ++D++ K + + LT N+  +
Sbjct: 808  ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 867

Query: 803  CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862
                    +    P+  + +L+++L  D + S+ALA E     ++ RKP  +NK      
Sbjct: 868  IVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK------ 921

Query: 863  PLAVYSYLHIGLMQALGAFLVYFT-VYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEW 921
            PL   + +   L  A    +V FT ++A E F                  D+        
Sbjct: 922  PLISRTMMKNILGHAFYQLVVVFTLLFAGEKFF-----------------DIDSGRNAPL 964

Query: 922  TRYQREYLEWTGYTAFF-VGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIII 980
                 E+     YT  F   +L+Q   ++  RK        +G+F N +    +    ++
Sbjct: 965  HAPPSEH-----YTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019

Query: 981  GLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIW 1015
             +I+    G   + S   +    W + +    L+W
Sbjct: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLW 1054



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 56/313 (17%)

Query: 23  DKGDGKEKYRGLKNNCLELKKKNHKEEFQ---------KELHLDDHKLSNRELEEKYG-- 71
           D  +    Y G+KN+   LK+ NH  +F           EL   D   + R+++E YG  
Sbjct: 3   DMANNSVAYSGVKNS---LKEANHDGDFGITLAELRALMELRSTD---ALRKIQESYGDV 56

Query: 72  --------TDIIMGLSSTRAAELLARDGP--NSLTPPKQTPEIVKFLKQMVGGFS-ILLW 120
                   T    GLS    A+L  R+     +  PPK+    ++ + + +   + I+L 
Sbjct: 57  YGICTKLKTSPNEGLSGN-PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILE 115

Query: 121 VGAF----------------LCW-IAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAY 163
           + A                 LC  ++ G +    ++  +    +   +  VV++T    +
Sbjct: 116 IAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDW 175

Query: 164 YQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSS 223
            +E +   + S   +   Q+  VIR  +   IP   + VGDI +VK GD +PAD  ++  
Sbjct: 176 SKEKQFRGLQSRIEQ--EQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQG 233

Query: 224 QGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIG 283
              ++D SSLTGES+   +S        L+   +    T  +EG+   +V   G  +  G
Sbjct: 234 NDLKIDESSLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTG 285

Query: 284 HIASLASGVGNEK 296
            I +L    G E+
Sbjct: 286 IIFTLLGAGGEEE 298


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
            sapiens]
          Length = 1220

 Score =  249 bits (635), Expect = 1e-65
 Identities = 224/755 (29%), Positives = 353/755 (46%), Gaps = 103/755 (13%)

Query: 297  TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLKYQVLDSIIFLIG 341
            T +A++I     +++ + V I +L+F+I                + ++Y V   II +  
Sbjct: 367  TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426

Query: 342  IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
            ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 427  LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485

Query: 402  TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIIT-----LCNRAEFKPGQENVP 456
            TV   + +         E H  +V +  +     LS ++T         ++  P ++   
Sbjct: 486  TVVQAYIN---------EKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536

Query: 457  IMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVA---EIPFNSTNKFQLSIHEMDDP 513
            + +   +G+ +E ALL     +  D  ++R    + A      FNS  K   ++ +  D 
Sbjct: 537  LPRH--VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDG 594

Query: 514  HGKRFLMVMKGAPERILEKCSTIM-INGEE---HPLDKSTAKTFHTAYMELGGLGERVLG 569
              + F    KGA E IL+KC  I+  NGE     P D+       T    +   G R + 
Sbjct: 595  SYRIF---SKGASEIILKKCFKILSANGEAKVFRPRDRDDI--VKTVIEPMASEGLRTIC 649

Query: 570  FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629
                  PA E PE    + D  N   + L  + ++ + DP R  VPDA+ KC+ AGI V 
Sbjct: 650  LAFRDFPAGE-PEP---EWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVR 705

Query: 630  MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689
            MVTGD+  TA+AIA   GI+    +        L +  +  N+R          E  ++ 
Sbjct: 706  MVTGDNINTARAIATKCGILHPGEDF-------LCLEGKDFNRRIRN-------EKGEIE 751

Query: 690  SEQLDEILANYQEIVFARTSPQQKLIIVEGC-------QRQDAVVAVTGDGVNDSPALKK 742
             E++D+I    +  V AR+SP  K  +V+G        QRQ  VVAVTGDG ND PALKK
Sbjct: 752  QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTNDGPALKK 807

Query: 743  ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802
            AD+G AMGIAG+D AK A+D++L DDNF SIV  V  GR ++D++ K + + LT N+  +
Sbjct: 808  ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 867

Query: 803  CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862
                    +    P+  + +L+++L  D + S+ALA E     ++ RKP  +NK      
Sbjct: 868  IVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK------ 921

Query: 863  PLAVYSYLHIGLMQALGAFLVYFT-VYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEW 921
            PL   + +   L  A    +V FT ++A E F                  D+        
Sbjct: 922  PLISRTMMKNILGHAFYQLVVVFTLLFAGEKFF-----------------DIDSGRNAPL 964

Query: 922  TRYQREYLEWTGYTAFF-VGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIII 980
                 E+     YT  F   +L+Q   ++  RK        +G+F N +    +    ++
Sbjct: 965  HAPPSEH-----YTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019

Query: 981  GLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIW 1015
             +I+    G   + S   +    W + +    L+W
Sbjct: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLW 1054



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 56/313 (17%)

Query: 23  DKGDGKEKYRGLKNNCLELKKKNHKEEFQ---------KELHLDDHKLSNRELEEKYG-- 71
           D  +    Y G+KN+   LK+ NH  +F           EL   D   + R+++E YG  
Sbjct: 3   DMANNSVAYSGVKNS---LKEANHDGDFGITLAELRALMELRSTD---ALRKIQESYGDV 56

Query: 72  --------TDIIMGLSSTRAAELLARDGP--NSLTPPKQTPEIVKFLKQMVGGFS-ILLW 120
                   T    GLS    A+L  R+     +  PPK+    ++ + + +   + I+L 
Sbjct: 57  YGICTKLKTSPNEGLSGN-PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILE 115

Query: 121 VGAF----------------LCW-IAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAY 163
           + A                 LC  ++ G +    ++  +    +   +  VV++T    +
Sbjct: 116 IAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDW 175

Query: 164 YQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSS 223
            +E +   + S   +   Q+  VIR  +   IP   + VGDI +VK GD +PAD  ++  
Sbjct: 176 SKEKQFRGLQSRIEQ--EQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQG 233

Query: 224 QGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIG 283
              ++D SSLTGES+   +S        L+   +    T  +EG+   +V   G  +  G
Sbjct: 234 NDLKIDESSLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTG 285

Query: 284 HIASLASGVGNEK 296
            I +L    G E+
Sbjct: 286 IIFTLLGAGGEEE 298


>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
           sapiens]
          Length = 1243

 Score =  248 bits (634), Expect = 2e-65
 Identities = 196/592 (33%), Positives = 303/592 (51%), Gaps = 70/592 (11%)

Query: 297 TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLKYQVLDSIIFLIG 341
           T +A++I     +++ + V I +L+F +                V ++Y V   II +  
Sbjct: 391 TKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTV 450

Query: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
           ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 451 LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRM 509

Query: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLC--NRA---EFKPGQENVP 456
           TV       Q +V D    H  ++ D SS    ++  +I     N A   +  P ++   
Sbjct: 510 TVV------QAYVGDV---HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560

Query: 457 IMKKAVIGDASETALLKFSEVILGDVMEIRKR--NRKVAEI-PFNSTNKFQLSIHEMDDP 513
           + ++  +G+ +E  LL F   +  D   +R +    K+ ++  FNS  K   ++ ++ D 
Sbjct: 561 LPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPD- 617

Query: 514 HGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAYMELGGLGERVLG 569
             + F M  KGA E +L+KC  I+    E     P D+          M   GL      
Sbjct: 618 --ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRT---- 671

Query: 570 FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629
            C  Y    +FP +   D D  N   + L  + ++ + DP R  VP+A+ KC+ AGI V 
Sbjct: 672 ICVAYR---DFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728

Query: 630 MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689
           MVTGD+  TA+AIA   GII    +        L +  ++ N+R          E  ++ 
Sbjct: 729 MVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIRN-------EKGEIE 774

Query: 690 SEQLDEILANYQEIVFARTSPQQKLIIVEGC-----QRQDAVVAVTGDGVNDSPALKKAD 744
            E++D+I    +  V AR+SP  K  +V+G        Q  VVAVTGDG ND PALKKAD
Sbjct: 775 QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKAD 832

Query: 745 IGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCP 804
           +G AMGIAG+D AK A+D++L DDNF+SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 833 VGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 892

Query: 805 FLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
                 +    P+  + +L+++L  D   S+ALA E     ++ RKP  +NK
Sbjct: 893 AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNK 944



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 10/143 (6%)

Query: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213
           VV++T    + +E +   + S   +   Q+  V+R  +   IP  ++VVGDI +VK GD 
Sbjct: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221

Query: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273
           +PAD   +     ++D SSLTGES+   +S        ++   +    T  +EG+   +V
Sbjct: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKS--------VDKDPMLLSGTHVMEGSGRMLV 273

Query: 274 INTGDRTIIGHIASLASGVGNEK 296
              G  +  G I +L    G E+
Sbjct: 274 TAVGVNSQTGIIFTLLGAGGEEE 296


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score =  247 bits (631), Expect = 4e-65
 Identities = 194/594 (32%), Positives = 304/594 (51%), Gaps = 74/594 (12%)

Query: 297 TPIAIEIEHFVHIVAGVAVSIGILFFIIA---------------VSLKYQVLDSIIFLIG 341
           T +A++I     +++ + V I +L+F+I                V ++Y V   II +  
Sbjct: 365 TKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTV 424

Query: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
           ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 425 LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRM 483

Query: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCN-----RAEFKPGQENVP 456
           TV       Q ++ DT   H  ++   S+ T   L  ++   +       +  P ++   
Sbjct: 484 TVV------QSYLGDT---HYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGA 534

Query: 457 IMKKAVIGDASETALLKFSEVILGDVMEIRKR---NRKVAEIPFNSTNKFQLSIHEMDDP 513
           + ++  +G+ +E ALL F   +  D   +R++   ++      FNS  K   ++  M D 
Sbjct: 535 LPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG 592

Query: 514 HGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAYMELGGLGERVLG 569
               F +  KGA E +L+KC+ I+ +  E     P D+          M   GL  R + 
Sbjct: 593 G---FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGL--RTIC 647

Query: 570 FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629
             +    A + P     D D  N    +L  + ++ + DP R  VP+A+ KC+ AGI V 
Sbjct: 648 IAYRDFSAGQEP-----DWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVR 702

Query: 630 MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689
           MVTGD+  TA+AIA   GII    +        L +  ++ N+R          E  ++ 
Sbjct: 703 MVTGDNINTARAIAAKCGIIQPGEDF-------LCLEGKEFNRRIRN-------EKGEIE 748

Query: 690 SEQLDEILANYQEIVFARTSPQQKLIIVEGC-------QRQDAVVAVTGDGVNDSPALKK 742
            E+LD++    +  V AR+SP  K  +V+G        QRQ  VVAVTGDG ND PALKK
Sbjct: 749 QERLDKVWPKLR--VLARSSPTDKHTLVKGIIDSTTGEQRQ--VVAVTGDGTNDGPALKK 804

Query: 743 ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802
           AD+G AMGIAG+D AK A+D++L DDNF SIV  V  GR ++D++ K + + LT N+  +
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864

Query: 803 CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856
                   +    P+  + +L+++L  D   S+ALA E     ++ RKP  ++K
Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDK 918



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 43/143 (30%), Positives = 74/143 (51%), Gaps = 10/143 (6%)

Query: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213
           VV++T    + +E +   + S   +   Q+  VIR+ +   +P   LVVGDI +VK GD 
Sbjct: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224

Query: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273
           +PAD  ++ +   ++D SSLTGES+   +S++   ++P+         T  +EG+   +V
Sbjct: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276

Query: 274 INTGDRTIIGHIASLASGVGNEK 296
              G  +  G I +L    G E+
Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEE 299


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,615,306
Number of Sequences: 37866
Number of extensions: 1513598
Number of successful extensions: 4369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4014
Number of HSP's gapped (non-prelim): 176
length of query: 1039
length of database: 18,247,518
effective HSP length: 112
effective length of query: 927
effective length of database: 14,006,526
effective search space: 12984049602
effective search space used: 12984049602
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.