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Search of human proteins with 73808266
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi... 566 e-162
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 196 1e-50
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens] 195 4e-50
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 191 6e-49
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 187 1e-47
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 186 2e-47
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 185 3e-47
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 183 1e-46
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 182 3e-46
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H... 172 2e-43
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens] 169 2e-42
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 156 2e-38
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 151 5e-37
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 144 1e-34
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 142 2e-34
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 142 2e-34
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 138 4e-33
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 134 8e-32
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 132 4e-31
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 132 4e-31
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ... 131 5e-31
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 131 7e-31
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 113 2e-25
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 112 4e-25
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens] 98 6e-21
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi... 89 5e-18
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ... 68 9e-12
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens] 50 2e-06
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens] 50 2e-06
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens] 48 1e-05
>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
Length = 261
Score = 567 bits (1460), Expect = e-162
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ 60
MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ
Sbjct: 1 MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ 60
Query: 61 FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV 120
FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV
Sbjct: 61 FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV 120
Query: 121 KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG 180
KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG
Sbjct: 121 KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG 180
Query: 181 NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL 240
NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL
Sbjct: 181 NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL 240
Query: 241 SADDIQRIQHLYGEKCSSDIP 261
SADDIQRIQHLYGEKCSSDIP
Sbjct: 241 SADDIQRIQHLYGEKCSSDIP 261
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 196 bits (499), Expect = 1e-50
Identities = 104/263 (39%), Positives = 144/263 (54%), Gaps = 14/263 (5%)
Query: 5 ILRVTIFLPW--CFAVPVPPAADH-----KGWDFVEGYFHQFFLTKKESPLLTQETQTQL 57
+L +FL W C A+P+P D + F E Y ++ + +L + + +
Sbjct: 5 VLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSM 64
Query: 58 LQQ-------FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIIN 110
++ F T LD ++ +P CGVPD + ++ P KW+K LTYRI+N
Sbjct: 65 TERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVN 124
Query: 111 YPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGI 170
Y DM S V+ + A +WS+VTPL F ++ +G ADI +SF H D +PFDGP G+
Sbjct: 125 YTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGL 184
Query: 171 LGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTY 230
L HAF P G HFD +E W++S GYNLFLVA HE GHSLGL HS + ++M+P Y
Sbjct: 185 LAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIY 244
Query: 231 WYHDPRTFQLSADDIQRIQHLYG 253
Y F L DD+Q IQ LYG
Sbjct: 245 TYTGKSHFMLPDDDVQGIQSLYG 267
>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
Length = 267
Score = 195 bits (495), Expect = 4e-50
Identities = 101/264 (38%), Positives = 153/264 (57%), Gaps = 6/264 (2%)
Query: 1 MQLVILRVTIFLPWCFAVPVPPAADHKG---WDFVEGYFHQFFLTKKESPLLTQ-ETQTQ 56
M+L +L LP A+P+P A W+ + Y +F+L E+ E + +
Sbjct: 1 MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK 60
Query: 57 LLQQFHRNG-TDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDM 115
+Q+F T +L+ ++ ++ +P CGVPD ++ S+ P KW +TYRI++Y D+
Sbjct: 61 EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL 120
Query: 116 KPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAF 175
V + A+++W PL F++V G ADI + F + AH D +PFDGPG L HAF
Sbjct: 121 PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF 180
Query: 176 LPNSGNPGVVHFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHD 234
P +G G HFD++E W+ S G N ATHE+GHSLG+ HS + +++MYPTY D
Sbjct: 181 APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD 240
Query: 235 PRTFQLSADDIQRIQHLYGEKCSS 258
P+ F+LS DDI+ IQ LYG++ +S
Sbjct: 241 PQNFKLSQDDIKGIQKLYGKRSNS 264
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 191 bits (485), Expect = 6e-49
Identities = 108/233 (46%), Positives = 132/233 (56%), Gaps = 9/233 (3%)
Query: 31 FVEGYFHQFF--------LTK-KESPLLTQETQTQLLQQFHRNGTDLLDMQMHALLHQPH 81
F E Y +F+ +TK K S L +E ++ T LD ++H P
Sbjct: 32 FGERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPR 91
Query: 82 CGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQ 141
CGVPD PG W KH +TYRI NY DM V +I A +WSNVTPL F +
Sbjct: 92 CGVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSK 151
Query: 142 VQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYN 201
+ G ADI V F + AH D FDG GGIL HAF P SG G HFD++E W+ G N
Sbjct: 152 INTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTN 211
Query: 202 LFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYGE 254
LFL A HEIGHSLGL HS + ++M+PTY Y D TF+LSADDI+ IQ LYG+
Sbjct: 212 LFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD 264
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 187 bits (474), Expect = 1e-47
Identities = 91/228 (39%), Positives = 132/228 (57%), Gaps = 4/228 (1%)
Query: 30 DFVEGYF----HQFFLTKKESPLLTQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVP 85
D++E ++ +Q+ T+K + E ++ + F N T + + ++ +P CGVP
Sbjct: 35 DYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVP 94
Query: 86 DGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNG 145
D ++PG KW + LTYRI NY + + V+ +I +A +WS +PLIF ++ G
Sbjct: 95 DSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQG 154
Query: 146 DADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLV 205
+ADI ++F+Q H D PFDGP GIL HAF P G G HFD E W+ + YNLFLV
Sbjct: 155 EADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLV 214
Query: 206 ATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
A HE GHSLGL HS + ++MYP Y + + + L DDI IQ +YG
Sbjct: 215 AAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG 262
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 186 bits (472), Expect = 2e-47
Identities = 106/254 (41%), Positives = 136/254 (53%), Gaps = 19/254 (7%)
Query: 15 CFAVPVPPAADHKGWD--------FVEGYFH------QFFLTKKESPLLTQETQTQLLQQ 60
C A P+ AA +G D ++E Y+ QF K P++ + + Q
Sbjct: 15 CSAYPLDGAA--RGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLG 72
Query: 61 FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV 120
G LD ++ +P CGVPD PG KW K LTYRI+NY D+ AV
Sbjct: 73 LEVTGK--LDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAV 130
Query: 121 KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG 180
++ A+ +W VTPL F ++ G+ADI +SF H D +PFDGPG +L HA+ P G
Sbjct: 131 DSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPG 190
Query: 181 NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYW-YHDPRTFQ 239
G HFD +E W+ TG NLFLVA HEIGHSLGL HS N ++MYP Y D F+
Sbjct: 191 INGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFR 250
Query: 240 LSADDIQRIQHLYG 253
LS DDI IQ LYG
Sbjct: 251 LSQDDINGIQSLYG 264
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 185 bits (470), Expect = 3e-47
Identities = 108/265 (40%), Positives = 147/265 (55%), Gaps = 15/265 (5%)
Query: 1 MQLVILRVTIFLPWCFAVPVPPAA--DHKGWDFVEGYFHQFF--------LTKKESPLLT 50
M L L V + LP C A P+ AA + D + Y +++ +K+S L+
Sbjct: 2 MHLAFL-VLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIV 60
Query: 51 QETQTQLLQQF-HRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRII 109
++ Q +Q+F T LD ++ +P CGVPD S PG KW K LTYRI+
Sbjct: 61 KKIQG--MQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIV 118
Query: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGG 169
NY D+ AV +I A+ +W VTPL F ++ G+ADI +SF H D + FDGPG
Sbjct: 119 NYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGH 178
Query: 170 ILGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPT 229
L HA+ P G G +HFD +E W+ +G NLFLVA HE+GHSLGL HS N ++MYP
Sbjct: 179 SLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPL 238
Query: 230 Y-WYHDPRTFQLSADDIQRIQHLYG 253
Y + + F+LS DD+ IQ LYG
Sbjct: 239 YNSFTELAQFRLSQDDVNGIQSLYG 263
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 183 bits (464), Expect = 1e-46
Identities = 87/190 (45%), Positives = 114/190 (60%)
Query: 66 TDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIY 125
T LD ++ +P CGVPD ++ + PG KW K+TLTYRI Y M V ++
Sbjct: 84 TGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVE 143
Query: 126 NAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVV 185
A+ WS+ PL F ++ +G+ADI +SF H D +PFDGP G L HAF P G G
Sbjct: 144 MALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDT 203
Query: 186 HFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDI 245
HFD E W+ G+NLF VA HE GH+LGL HS + S++MYPTY Y +P F L DD+
Sbjct: 204 HFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDV 263
Query: 246 QRIQHLYGEK 255
+ IQ LYG +
Sbjct: 264 KGIQALYGPR 273
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 182 bits (461), Expect = 3e-46
Identities = 105/265 (39%), Positives = 143/265 (53%), Gaps = 16/265 (6%)
Query: 1 MQLVILRVTIFLPWCFAVP-VPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQ 59
M+ ++L F+ + A P V + + + Y +QF+ + E L Q L+
Sbjct: 1 MKRLLLLFLFFITFSSAFPLVRMTENEENMQLAQAYLNQFYSLEIEGNHLVQSKNRSLID 60
Query: 60 Q--------FHRNGTDLLDMQMHALLHQPHCGVPD-GSDTSISPGRCKWNKHTLTYRIIN 110
F T LD ++ P CGVPD G PG W K+ LTYRIIN
Sbjct: 61 DKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTLPG---WRKYNLTYRIIN 117
Query: 111 YPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWP--FDGPG 168
Y DM +AV ++I + +WS VTPL F ++ G ADI ++F H P FDGP
Sbjct: 118 YTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVH-GRCPRYFDGPL 176
Query: 169 GILGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYP 228
G+LGHAF P G G HFD++E+W+ G+NLFLVA HE GH+LGL HS +Q+++M+P
Sbjct: 177 GVLGHAFPPGPGLGGDTHFDEDENWTKDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFP 236
Query: 229 TYWYHDPRTFQLSADDIQRIQHLYG 253
Y DPR + LS DDI IQ +YG
Sbjct: 237 NYVSLDPRKYPLSQDDINGIQSIYG 261
>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
sapiens]
Length = 469
Score = 172 bits (437), Expect = 2e-43
Identities = 93/232 (40%), Positives = 129/232 (55%), Gaps = 10/232 (4%)
Query: 30 DFVEGYFHQFFLTKKESPLLTQ--------ETQTQLLQQFHRNGTDLLDMQMHALLHQPH 81
D V+ Y +++ K + + + E Q+ + F T D + ++ QP
Sbjct: 32 DLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPR 91
Query: 82 CGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQ 141
CGVPD + ++ G +W + LTYRI NY D+ + V +I A +WSNVTPL F +
Sbjct: 92 CGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTK 151
Query: 142 VQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYN 201
V G ADI +SF + H D PFDGPGG L HAF P G G HFD++E W+ + YN
Sbjct: 152 VSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYN 211
Query: 202 LFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
L VA HE+GHSLGL HS + ++MYP+Y + QL+ DDI IQ +YG
Sbjct: 212 LHRVAAHELGHSLGLSHSTDIGALMYPSYTFSG--DVQLAQDDIDGIQAIYG 261
>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
Length = 403
Score = 169 bits (429), Expect = 2e-42
Identities = 85/184 (46%), Positives = 112/184 (60%), Gaps = 2/184 (1%)
Query: 70 DMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVS 129
D + ++ QP CGVPD + ++ G +W + LTYRI NY D+ + V +I A
Sbjct: 14 DAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQ 73
Query: 130 IWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDK 189
+WSNVTPL F +V G ADI +SF + H D PFDGPGG L HAF P G G HFD+
Sbjct: 74 LWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDE 133
Query: 190 NEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQ 249
+E W+ + YNL VA HE+GHSLGL HS + ++MYP+Y + QL+ DDI IQ
Sbjct: 134 DERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSG--DVQLAQDDIDGIQ 191
Query: 250 HLYG 253
+YG
Sbjct: 192 AIYG 195
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 156 bits (395), Expect = 2e-38
Identities = 82/187 (43%), Positives = 107/187 (57%), Gaps = 11/187 (5%)
Query: 77 LHQPHCGVPDGSDTSISPGRCK--------WNKHTLTYRIINYPHDMKPSAVKDSIYNAV 128
L P CGVPD SD + R K W K LTYRI+ +P + V+ ++ A+
Sbjct: 75 LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134
Query: 129 SIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFD 188
+WS+VTPL F +V G ADI + F ++ H D PFDGPGGIL HAF P + G VHFD
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFD 194
Query: 189 KNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQR 247
+E W+ D G +L VA HE GH LGLQH+ ++M Y + P LS DD +
Sbjct: 195 YDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYP--LSLSPDDCRG 252
Query: 248 IQHLYGE 254
+QHLYG+
Sbjct: 253 VQHLYGQ 259
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 151 bits (382), Expect = 5e-37
Identities = 86/211 (40%), Positives = 111/211 (52%), Gaps = 24/211 (11%)
Query: 66 TDLLDMQMHALLHQPHCGVPDGSDTSISP------------GRCKWNKHTLTYRIINYPH 113
T +LD + + +P CGVPD + GR KWN H LT+ I NY
Sbjct: 95 TGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGR-KWNNHHLTFSIQNYTE 153
Query: 114 DMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGD--------ADIKVSFWQWAHEDGWPFD 165
+ +++ A +W TPL+FQ+V D ADI V F H D PFD
Sbjct: 154 KLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFD 213
Query: 166 GPGGILGHAFLPNSGNPGVVHFDKNEHWSASDT---GYNLFLVATHEIGHSLGLQHSGNQ 222
G GG L HA+ P G G HFD +E W+ S T G NLFLVA HE+GH+LGL+HS N
Sbjct: 214 GTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNP 273
Query: 223 SSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
++IM P Y + D F+L DD++ IQ LYG
Sbjct: 274 NAIMAPFYQWKDVDNFKLPEDDLRGIQQLYG 304
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 144 bits (362), Expect = 1e-34
Identities = 84/221 (38%), Positives = 116/221 (52%), Gaps = 20/221 (9%)
Query: 52 ETQTQLLQQFHRNG-TDLLDMQMHALLHQPHCGVPDGSDTS--------ISPGRCKWNKH 102
++ +QQF+ T +LD + +P CGVPD S G+ KW +
Sbjct: 108 QSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQ-KWRQK 166
Query: 103 TLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQV-------QNGDADIKVSFWQ 155
+TY I NY + + +I A +W VTPL F++V +ADI + F
Sbjct: 167 HITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFAS 226
Query: 156 WAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWS---ASDTGYNLFLVATHEIGH 212
H D PFDG GG L HA+ P G G HFD +E W+ A+ G +LFLVA HE+GH
Sbjct: 227 GFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGH 286
Query: 213 SLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
+LGL+HS + S+IM P Y Y + F+L DD+Q IQ +YG
Sbjct: 287 ALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYG 327
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 142 bits (359), Expect = 2e-34
Identities = 86/224 (38%), Positives = 117/224 (52%), Gaps = 20/224 (8%)
Query: 50 TQETQTQLLQQFHR-NGTDLLDMQMHALLHQPHCGVPD----GSDTSISPGRC-----KW 99
T ++ +QQF+ N T +D + +P CGVPD S I R KW
Sbjct: 68 TMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKW 127
Query: 100 NKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQV-----QNG--DADIKVS 152
+TY I N + + +I A +W NVTPL F++V +NG D DI +
Sbjct: 128 QHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITII 187
Query: 153 FWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDT---GYNLFLVATHE 209
F H D PFDG GG L HA+ P G G HFD +E W+ + G +LFLVA HE
Sbjct: 188 FASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHE 247
Query: 210 IGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
+GH+LGL+HS + ++IM P Y Y + F+L DD+Q IQ +YG
Sbjct: 248 LGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYG 291
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 142 bits (359), Expect = 2e-34
Identities = 86/224 (38%), Positives = 117/224 (52%), Gaps = 20/224 (8%)
Query: 50 TQETQTQLLQQFHR-NGTDLLDMQMHALLHQPHCGVPD----GSDTSISPGRC-----KW 99
T ++ +QQF+ N T +D + +P CGVPD S I R KW
Sbjct: 68 TMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKW 127
Query: 100 NKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQV-----QNG--DADIKVS 152
+TY I N + + +I A +W NVTPL F++V +NG D DI +
Sbjct: 128 QHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITII 187
Query: 153 FWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDT---GYNLFLVATHE 209
F H D PFDG GG L HA+ P G G HFD +E W+ + G +LFLVA HE
Sbjct: 188 FASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHE 247
Query: 210 IGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
+GH+LGL+HS + ++IM P Y Y + F+L DD+Q IQ +YG
Sbjct: 248 LGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYG 291
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 138 bits (348), Expect = 4e-33
Identities = 82/224 (36%), Positives = 116/224 (51%), Gaps = 18/224 (8%)
Query: 48 LLTQETQTQLLQQFHRNG----TDLLDMQMHALLHQPHCGVPD------GSDTSISPGRC 97
L TQE ++ + + G T +LD AL+ P C +PD +P
Sbjct: 72 LQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPT 131
Query: 98 KWNKHTLTYRIINYPHD--MKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQ 155
KWNK L++R+ +P D + V+ +Y A+ +WS++ PL F +V ADI++ F +
Sbjct: 132 KWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSK 191
Query: 156 WAHEDGWPFDGPGGILGHAFLP-NSGNPGVVHFDKNEHW---SASDTGYNLFLVATHEIG 211
H DG+PFDGPGG + HAF P + G HFD +E W S+ G +LF VA HE G
Sbjct: 192 ADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFG 251
Query: 212 HSLGLQHSGNQSSIMYPTYW--YHDPRTFQLSADDIQRIQHLYG 253
H++GL H SIM P Y DP + L +D R+ LYG
Sbjct: 252 HAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYG 295
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 134 bits (337), Expect = 8e-32
Identities = 79/193 (40%), Positives = 111/193 (57%), Gaps = 12/193 (6%)
Query: 69 LDMQMHALLHQPHCGVPDGSDTS----ISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSI 124
LD A + QP CG+ D + + GR W K LT+RI+N P + P + ++
Sbjct: 72 LDDATRARMRQPRCGLEDPFNQKTLKYLLLGR--WRKKHLTFRILNLPSTLPPHTARAAL 129
Query: 125 YNAVSIWSNVTPLIFQQVQNGDADIKVSF-WQWAHEDGWPFDGPGGILGHAFLPNSGNPG 183
A WSNV PL FQ+VQ G ADI++SF + + FDGPG +L HA +P G+
Sbjct: 130 RQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGS-- 187
Query: 184 VVHFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSA 242
VHFD++E W+ + G NL ++A HE+GH+LGL HS ++M P Y + P F+L
Sbjct: 188 -VHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH-FKLHP 245
Query: 243 DDIQRIQHLYGEK 255
DD+ IQ LYG+K
Sbjct: 246 DDVAGIQALYGKK 258
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 132 bits (331), Expect = 4e-31
Identities = 64/165 (38%), Positives = 97/165 (58%), Gaps = 2/165 (1%)
Query: 35 YFHQFFLTKKESPLL--TQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSI 92
Y + F+ KES L ++T ++ + F T LD + +P CG PD ++ +
Sbjct: 3 YLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF 62
Query: 93 SPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVS 152
P + KW+K+ +TYRII Y D+ P V D+ A +WS+VTPL F ++ +G+ADI ++
Sbjct: 63 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN 122
Query: 153 FWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASD 197
F +W H DG+PFDG G+L HAF P +G G HFD +E W+ +
Sbjct: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGE 167
Score = 69.7 bits (169), Expect = 2e-12
Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Query: 186 HFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADD 244
++D + W D GY+LFLVA HE GH++GL+HS + ++M P Y Y + F+LS DD
Sbjct: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQDD 387
Query: 245 IQRIQHLYGEKCSSDI 260
I+ IQ LYG D+
Sbjct: 388 IKGIQELYGASPDIDL 403
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 132 bits (331), Expect = 4e-31
Identities = 64/165 (38%), Positives = 97/165 (58%), Gaps = 2/165 (1%)
Query: 35 YFHQFFLTKKESPLL--TQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSI 92
Y + F+ KES L ++T ++ + F T LD + +P CG PD ++ +
Sbjct: 53 YLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF 112
Query: 93 SPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVS 152
P + KW+K+ +TYRII Y D+ P V D+ A +WS+VTPL F ++ +G+ADI ++
Sbjct: 113 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN 172
Query: 153 FWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASD 197
F +W H DG+PFDG G+L HAF P +G G HFD +E W+ +
Sbjct: 173 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGE 217
Score = 69.7 bits (169), Expect = 2e-12
Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Query: 186 HFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADD 244
++D + W D GY+LFLVA HE GH++GL+HS + ++M P Y Y + F+LS DD
Sbjct: 380 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQDD 437
Query: 245 IQRIQHLYGEKCSSDI 260
I+ IQ LYG D+
Sbjct: 438 IKGIQELYGASPDIDL 453
>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
[Homo sapiens]
Length = 520
Score = 131 bits (330), Expect = 5e-31
Identities = 73/167 (43%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Query: 98 KWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQV-QNGDADIKVSFWQW 156
KW K L+YR++N+P + AV+ ++ A +WSNV+ L F + G ADI+++F+Q
Sbjct: 129 KWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQG 188
Query: 157 AHEDGW--PFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSAS-DTGYNLFLVATHEIGHS 213
H DG FDGPGG L HAFLP G HFD++E WS S G NLF+V HEIGH+
Sbjct: 189 DHNDGLGNAFDGPGGALAHAFLPRRGE---AHFDQDERWSLSRRRGRNLFVVLAHEIGHT 245
Query: 214 LGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYGEKCSSDI 260
LGL HS ++M P Y+ R LS DD+ +Q LYG+ +
Sbjct: 246 LGLTHSPAPRALMAP-YYKRLGRDALLSWDDVLAVQSLYGKPLGGSV 291
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 131 bits (329), Expect = 7e-31
Identities = 76/208 (36%), Positives = 105/208 (50%), Gaps = 20/208 (9%)
Query: 66 TDLLDMQMHALLHQPHCGVPD--GSDTSISPGR-------CKWNKHTLTYRIINYPHDMK 116
T D + +P CGVPD G++ + R KW + +T+ I NY +
Sbjct: 77 TGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVG 136
Query: 117 PSAVKDSIYNAVSIWSNVTPLIFQQV--------QNGDADIKVSFWQWAHEDGWPFDGPG 168
A ++I A +W + TPL F++V ADI + F + H D PFDG G
Sbjct: 137 EYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEG 196
Query: 169 GILGHAFLPNSGNPGVVHFDKNEHWSASD---TGYNLFLVATHEIGHSLGLQHSGNQSSI 225
G L HA+ P G HFD E W+ + G ++FLVA HE+GH+LGL+HS + S+I
Sbjct: 197 GFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAI 256
Query: 226 MYPTYWYHDPRTFQLSADDIQRIQHLYG 253
M P Y + D F L DD + IQ LYG
Sbjct: 257 MAPFYQWMDTENFVLPDDDRRGIQQLYG 284
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 113 bits (282), Expect = 2e-25
Identities = 75/208 (36%), Positives = 103/208 (49%), Gaps = 19/208 (9%)
Query: 66 TDLLDMQMHALLHQPHCGVPDGSDTSISPGRCK--------WNKHTLTYRIINYPHDMKP 117
T +D A + +P C +PD + R + W K TLT+R+ ++P +
Sbjct: 74 TGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQL 133
Query: 118 S--AVKDSIYNAVSIWSNVTPLIFQQV---QNGDADIKVSFWQWAHEDGWPFDGPGGILG 172
S V+ + A+ W + L F +V Q + DI + F + H+D +PFDG GG L
Sbjct: 134 SQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLA 193
Query: 173 HAFLPNSGN-PGVVHFDKNEHW---SASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYP 228
HAF P G HFD E W S G +LF VA HE GH+LGL HS +SIM P
Sbjct: 194 HAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRP 253
Query: 229 TYW--YHDPRTFQLSADDIQRIQHLYGE 254
Y DP ++LS DD +Q LYG+
Sbjct: 254 FYQGPVGDPDKYRLSQDDRDGLQQLYGK 281
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 112 bits (279), Expect = 4e-25
Identities = 57/138 (41%), Positives = 73/138 (52%)
Query: 57 LLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMK 116
L +Q T LD + P CGVPD G KW+ H +TY I NY D+
Sbjct: 74 LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLP 133
Query: 117 PSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFL 176
+ + D+ A ++WS VTPL F +V + DADI + F H DG+PFDG G+L HAF
Sbjct: 134 RAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFP 193
Query: 177 PNSGNPGVVHFDKNEHWS 194
P G G HFD +E WS
Sbjct: 194 PGPGIQGDAHFDDDELWS 211
Score = 65.9 bits (159), Expect = 3e-11
Identities = 32/71 (45%), Positives = 44/71 (61%), Gaps = 3/71 (4%)
Query: 186 HFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADD 244
+FD ++ W D GY+LFLVA HE GH+LGL HS ++MYP Y + + L DD
Sbjct: 378 NFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGP--PLHKDD 435
Query: 245 IQRIQHLYGEK 255
+ I+HLYG +
Sbjct: 436 VNGIRHLYGPR 446
>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
Length = 390
Score = 98.2 bits (243), Expect = 6e-21
Identities = 59/180 (32%), Positives = 95/180 (52%), Gaps = 22/180 (12%)
Query: 91 SISPGRCKWNKHTLTYRIINYPHDM-KPSAVKDSIYNAVSIWSNVTPLIFQQVQ-NGDAD 148
+++P R +W+ LTYRI+++P ++ P + ++ A +WS+V+P F++V +D
Sbjct: 80 TLTPARLRWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSD 139
Query: 149 IKVSFWQWAHEDGWP------FDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYN- 201
+++ F+ H D FDGP G L HAF P G +HFD +E+W T Y+
Sbjct: 140 LRIGFYPINHTDCLVSALHHCFDGPTGELAHAFFPPHGG---IHFDDSEYWVLGPTRYSW 196
Query: 202 --------LFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
L VA HEIGH+LGL HS + ++M+ + LS D++ + LYG
Sbjct: 197 KKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKA--LSQDELWGLHRLYG 254
>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
sapiens]
Length = 569
Score = 88.6 bits (218), Expect = 5e-18
Identities = 66/180 (36%), Positives = 89/180 (49%), Gaps = 22/180 (12%)
Query: 83 GVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDS--IYNAVSIWSNVTPLIFQ 140
G PDG ++K TL++R++ + S + A +WS VTPL F+
Sbjct: 161 GYPDGGAAQA------FSKRTLSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFR 214
Query: 141 Q---VQNGDADIKVSFWQWAHEDGWP--FDGPGGILGHAFLPNSGNPGVVHFDKNEHWS- 194
+ DIK+ F + H G P FDG G HA+ G +HFD +EH++
Sbjct: 215 EDLAAPGAAVDIKLGFGRGRHL-GCPRAFDGSGQEFAHAW-----RLGDIHFDDDEHFTP 268
Query: 195 -ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYG 253
SDTG +L VA HEIGH LGL H+ SIM P Y +P F+L D + IQ LYG
Sbjct: 269 PTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQEP-AFELDWSDRKAIQKLYG 327
>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
sapiens]
Length = 183
Score = 67.8 bits (164), Expect = 9e-12
Identities = 41/105 (39%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 69 LDMQMHALLHQPHCGVPDGSDTS----ISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSI 124
LD A + QP CG+ D + + GR W K LT+RI+N P + P + ++
Sbjct: 72 LDDATRARMRQPRCGLEDPFNQKTLKYLLLGR--WRKKHLTFRILNLPSTLPPHTARAAL 129
Query: 125 YNAVSIWSNVTPLIFQQVQNGDADIKVSF-WQWAHEDGWPFDGPG 168
A WSNV PL FQ+VQ G ADI++SF + + FDGPG
Sbjct: 130 RQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 358
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168
NY ++ V + A +WSN + L F + + DI +SF A D PF G
Sbjct: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 247
Query: 169 GILGHAFLPNSGNPGVVHFDKNE 191
G L HAF P G G VHFD +E
Sbjct: 248 GCLAHAFPPGPGIGGDVHFDNDE 270
>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 198
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168
NY ++ V + A +WSN + L F + + DI +SF A D PF G
Sbjct: 28 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
Query: 169 GILGHAFLPNSGNPGVVHFDKNE 191
G L HAF P G G VHFD +E
Sbjct: 88 GCLAHAFPPGPGIGGDVHFDNDE 110
>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 198
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168
NY ++ V + A +WS + L F + + DI +SF A D PF G
Sbjct: 28 NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
Query: 169 GILGHAFLPNSGNPGVVHFDKNE 191
G L HAF P G G VHFD +E
Sbjct: 88 GCLAHAFPPGPGIGGDVHFDNDE 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.461
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,704,405
Number of Sequences: 37866
Number of extensions: 550482
Number of successful extensions: 1100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 993
Number of HSP's gapped (non-prelim): 58
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.