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Search of human proteins with 6912458
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912458 calcineurin binding protein 1 [Homo sapiens]
(2220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912458 calcineurin binding protein 1 [Homo sapiens] 4470 0.0
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 72 8e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 72 8e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 72 8e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 72 8e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 71 1e-11
gi|116284392 mucin 2 precursor [Homo sapiens] 67 1e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 1e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 2e-09
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 63 4e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 6e-09
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 62 6e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 8e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 61 1e-08
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 59 5e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 58 9e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 58 9e-08
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 58 9e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 58 1e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 58 1e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 58 1e-07
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 56 4e-07
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 56 4e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 55 6e-07
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 55 6e-07
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 55 1e-06
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 55 1e-06
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 55 1e-06
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 55 1e-06
gi|54860079 nadrin isoform 1 [Homo sapiens] 54 1e-06
>gi|6912458 calcineurin binding protein 1 [Homo sapiens]
Length = 2220
Score = 4470 bits (11593), Expect = 0.0
Identities = 2220/2220 (100%), Positives = 2220/2220 (100%)
Query: 1 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH 60
MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
Sbjct: 1 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH 60
Query: 61 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD 120
ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
Sbjct: 61 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD 120
Query: 121 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF 180
STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
Sbjct: 121 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF 180
Query: 181 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA 240
ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
Sbjct: 181 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA 240
Query: 241 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL 300
LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
Sbjct: 241 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL 300
Query: 301 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET 360
SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
Sbjct: 301 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET 360
Query: 361 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS 420
GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
Sbjct: 361 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS 420
Query: 421 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT 480
RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
Sbjct: 421 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT 480
Query: 481 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD 540
NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
Sbjct: 481 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD 540
Query: 541 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS 600
MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
Sbjct: 541 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS 600
Query: 601 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR 660
SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
Sbjct: 601 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR 660
Query: 661 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG 720
DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
Sbjct: 661 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG 720
Query: 721 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK 780
FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
Sbjct: 721 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK 780
Query: 781 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP 840
EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
Sbjct: 781 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP 840
Query: 841 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG 900
HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
Sbjct: 841 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG 900
Query: 901 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA 960
RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
Sbjct: 901 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA 960
Query: 961 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE 1020
RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
Sbjct: 961 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE 1020
Query: 1021 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH 1080
RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
Sbjct: 1021 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH 1080
Query: 1081 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL 1140
DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
Sbjct: 1081 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL 1140
Query: 1141 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD 1200
SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
Sbjct: 1141 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD 1200
Query: 1201 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA 1260
GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
Sbjct: 1201 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA 1260
Query: 1261 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD 1320
LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
Sbjct: 1261 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD 1320
Query: 1321 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA 1380
EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
Sbjct: 1321 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA 1380
Query: 1381 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL 1440
VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
Sbjct: 1381 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL 1440
Query: 1441 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG 1500
ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
Sbjct: 1441 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG 1500
Query: 1501 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW 1560
AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
Sbjct: 1501 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW 1560
Query: 1561 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS 1620
QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
Sbjct: 1561 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS 1620
Query: 1621 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG 1680
TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
Sbjct: 1621 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG 1680
Query: 1681 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS 1740
LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
Sbjct: 1681 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS 1740
Query: 1741 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE 1800
ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
Sbjct: 1741 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE 1800
Query: 1801 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL 1860
ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
Sbjct: 1801 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL 1860
Query: 1861 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA 1920
LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
Sbjct: 1861 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA 1920
Query: 1921 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP 1980
SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
Sbjct: 1921 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP 1980
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
Sbjct: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
Query: 2041 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS 2100
APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
Sbjct: 2041 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS 2100
Query: 2101 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
Sbjct: 2101 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
Query: 2161 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI 2220
KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
Sbjct: 2161 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI 2220
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 71.6 bits (174), Expect = 8e-12
Identities = 123/547 (22%), Positives = 188/547 (34%), Gaps = 72/547 (13%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR 1754
+P +E P K+P P P K + A + + KE
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSP 382
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPE----SRPTELSLEELSISARQQP 1810
P EP T+ + + E P P + P P + +E + + ++P
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 442
Query: 1811 TPLTPAQPAPA----PAPATTTGTRAGGHPEEPLSRLSRKR-----KLLEDTESGKTLLL 1861
P TP +PAP PAP TTT A P+EP ++ K L T K
Sbjct: 443 APTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 1862 DAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
+ + +A EE + AAA
Sbjct: 502 TPEKPAPTTPEELA-----------------PTTPEEPTPTTPEEPAPTTPKAAAPNTPK 544
Query: 1922 GDTPTTPKHPKDSREN----FFPVTVVPTAPDPVPADSVQRPS-DAHTKPRPALAAATTI 1976
PTTPK P + P PT P +++ P+ KP P A TT
Sbjct: 545 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 604
Query: 1977 -----ITC----PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSF 2027
TC P + + K+P P P P T P+G + E
Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT------PKGTAPTTLKEPAPT 658
Query: 2028 PPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAE--PTCSQEGKLRPEPRRDGEAQEA 2085
P++P +P+ ++APT++ + A T E PT +E P P +
Sbjct: 659 TPKKP--APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPT 711
Query: 2086 ASETQP--LSSPPTAASSKAPSSGSAQPPEGHP---GKPEPSRAKSRPL-PNMPKLVIPS 2139
ET P S T ++K P++ P E P +P P ++ P P +P P
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP- 770
Query: 2140 AATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLE 2199
AATK PE+T T T + E T K +A + + + +V
Sbjct: 771 AATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 828
Query: 2200 TSSQESS 2206
T++Q+++
Sbjct: 829 TTTQDTT 835
Score = 68.9 bits (167), Expect = 5e-11
Identities = 119/526 (22%), Positives = 181/526 (34%), Gaps = 77/526 (14%)
Query: 1704 PQPKKPPLADGSGPGPEPG--------------GKVGL---------LNHRPVAMDAGDS 1740
P PK PP+ D +G G + G KV +N RP D+
Sbjct: 78 PTPK-PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 136
Query: 1741 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPL-----LPGRPARDRGPESR-- 1793
+ ++ +KE+ T+ T+ E+T + A+D P S+
Sbjct: 137 SKETSLTVNKET--TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194
Query: 1794 --PT---ELSLEELSISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRK 1846
PT E + + +++ ++PTP TP +PA P TT A P+EP ++
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 1847 RKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVK 1906
+ T A ++ + + T +E A K
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKK 308
Query: 1907 FCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVT---VVPTAP-DPVPADSVQRPSDA 1962
A TPTTPK P + + P T PTAP P P +
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 1963 HTKPRPALA---AATTIITCPPSASASTLDQSKDPGP---------PRPHRPEATPSMAS 2010
+P P + TT P+ + S +K+P P P+ P T A
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 2011 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEG 2070
P+ + P+EP + + APT++ P E A T E +
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488
Query: 2071 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP 2130
KL P E + T P PT AP++ +P P +P P+ K+ P
Sbjct: 489 KLTP------TTPEKLAPTTPEKPAPTTPEELAPTT-PEEPTPTTPEEPAPTTPKA-AAP 540
Query: 2131 NMPKLVIPSAATKFPPEITVTPPTPTL------LSPKGSISEETKQ 2170
N PK P+ K P T P PT +PKG+ K+
Sbjct: 541 NTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Score = 68.2 bits (165), Expect = 9e-11
Identities = 103/505 (20%), Positives = 149/505 (29%), Gaps = 47/505 (9%)
Query: 1674 PGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPV 1733
P KV P + T A + PK+P P P P
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 1734 AMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHS--DLERTPPLLPGRPARDRGPE 1791
+ E + PT P + + T ++ P P PA +
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 1792 SRPTELSLEELSISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRKRKL 1849
PT ++P P TP +P P PA TT A P+EP +K
Sbjct: 309 PAPT----------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1850 LEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQ 1909
E T + + + + T + K
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 1910 VHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAP-DPVPADSVQRPSDAHTKPRP 1968
+ PTTPK P + P PT P +P P + KP P
Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468
Query: 1969 ALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFP 2028
P A T + P P+ P +A PE E
Sbjct: 469 T----------TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 2029 PQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASE 2088
P+EP + + APT+ A P E A T EP + + P ++ +
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE------TAP 572
Query: 2089 TQPLSSPPTAASSKAPSSGSAQPPE---GHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP 2145
T P + PT AP++ P+ K S +P P PK P+ +
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632
Query: 2146 PEITVTPPTPTLLSPKGSISEETKQ 2170
P TP P +PKG+ K+
Sbjct: 633 P---TTPKEPAPTTPKGTAPTTLKE 654
Score = 67.4 bits (163), Expect = 1e-10
Identities = 120/537 (22%), Positives = 175/537 (32%), Gaps = 65/537 (12%)
Query: 1695 SPEDGQEGLPQ-PKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP 1753
+P +E P PK+P P P P A + + KE
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP----APTTPKKPAPTTPKEPA 318
Query: 1754 RAGPTEPMDTSEATVCHSDLERTP-------PLLPGRPARDRGPESRPTELSLEELSISA 1806
P EP T+ + E P P P +PA E PT + +E + +
Sbjct: 319 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT--TPKEPAPTT 376
Query: 1807 RQQPTPLTPAQPAP-----APA----PATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGK 1857
++P+P TP +PAP AP PA TT A P+EP +++ E
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436
Query: 1858 TLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQ 1917
T K A + +E A K A
Sbjct: 437 TT-----------PKKPAPTTPKEP---------APTTPKEPAPTTTKKPAPTTPKEPAP 476
Query: 1918 RQASGDTPTTPKH-PKDSRENFFPVT---VVPTAPDPVPADSVQRPSDAHTKPRPALAAA 1973
PTTPK + E P T PT P+ + + + P+ T PA
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT-TPEEPAPTTP 535
Query: 1974 TTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPR 2033
P A T + P P+ P A P+G + E P++P
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP- 594
Query: 2034 HSPQVKMAPTSS--PAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQP 2091
+P+ ++APT++ P C G PT +E P P E + T P
Sbjct: 595 -APK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKE----PAPTTP 644
Query: 2092 LSSPPTAASSKAPSSGSAQPPE---GHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEI 2148
+ PT AP++ P+ K S +P P PK P+ + P
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 2149 TVTPPTPTLLSPKGSISE-ETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQE 2204
P T +P + SE T K +S E +P + LE S +E
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 761
Score = 46.6 bits (109), Expect = 3e-04
Identities = 103/476 (21%), Positives = 148/476 (31%), Gaps = 68/476 (14%)
Query: 1656 TVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQ-PKKPPLADG 1714
T K T E A + + P P T + +P +E P PKKP
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE----PAPTTPKEPAPTTPKKPAPTTP 447
Query: 1715 SGPGPE-PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR------------AGPTEPM 1761
P P P +P + A + + +P+ P +P
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
T+ + + E P P PA + P + +E + + ++P P TP +PAP
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 1822 PAPATTTGTRAGGHP---EEPLSRLSRK--RKLLEDTESGKTLLLDAYRVWQQGQKGVAY 1876
T T G P +EP +K K L T + + + KG A
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA- 624
Query: 1877 DLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRE 1936
+E A + A G PTT K P
Sbjct: 625 ----------------PTTPKEPAPTTPKE--------PAPTTPKGTAPTTLKEPA---- 656
Query: 1937 NFFPVTVVPTAPDPVPADSVQRP-SDAHTKPRPALAAATTIITCPPSASASTLDQSKDPG 1995
P T AP + + + P S KP P T T P A T K P
Sbjct: 657 ---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPT--TPKKPA 709
Query: 1996 PPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAE 2055
P P P T S S +E + + E P K A +SP EP +
Sbjct: 710 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTK 768
Query: 2056 AALGTGAEPTCSQEGK-----LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS 2106
T E T + + K LR P A + ET + T + A ++
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 824
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 71.6 bits (174), Expect = 8e-12
Identities = 123/547 (22%), Positives = 188/547 (34%), Gaps = 72/547 (13%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR 1754
+P +E P K+P P P K + A + + KE
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSP 423
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPE----SRPTELSLEELSISARQQP 1810
P EP T+ + + E P P + P P + +E + + ++P
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 483
Query: 1811 TPLTPAQPAPA----PAPATTTGTRAGGHPEEPLSRLSRKR-----KLLEDTESGKTLLL 1861
P TP +PAP PAP TTT A P+EP ++ K L T K
Sbjct: 484 APTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 1862 DAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
+ + +A EE + AAA
Sbjct: 543 TPEKPAPTTPEELA-----------------PTTPEEPTPTTPEEPAPTTPKAAAPNTPK 585
Query: 1922 GDTPTTPKHPKDSREN----FFPVTVVPTAPDPVPADSVQRPS-DAHTKPRPALAAATTI 1976
PTTPK P + P PT P +++ P+ KP P A TT
Sbjct: 586 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 645
Query: 1977 -----ITC----PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSF 2027
TC P + + K+P P P P T P+G + E
Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT------PKGTAPTTLKEPAPT 699
Query: 2028 PPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAE--PTCSQEGKLRPEPRRDGEAQEA 2085
P++P +P+ ++APT++ + A T E PT +E P P +
Sbjct: 700 TPKKP--APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPT 752
Query: 2086 ASETQP--LSSPPTAASSKAPSSGSAQPPEGHP---GKPEPSRAKSRPL-PNMPKLVIPS 2139
ET P S T ++K P++ P E P +P P ++ P P +P P
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP- 811
Query: 2140 AATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLE 2199
AATK PE+T T T + E T K +A + + + +V
Sbjct: 812 AATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 869
Query: 2200 TSSQESS 2206
T++Q+++
Sbjct: 870 TTTQDTT 876
Score = 68.9 bits (167), Expect = 5e-11
Identities = 119/526 (22%), Positives = 181/526 (34%), Gaps = 77/526 (14%)
Query: 1704 PQPKKPPLADGSGPGPEPG--------------GKVGL---------LNHRPVAMDAGDS 1740
P PK PP+ D +G G + G KV +N RP D+
Sbjct: 119 PTPK-PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 177
Query: 1741 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPL-----LPGRPARDRGPESR-- 1793
+ ++ +KE+ T+ T+ E+T + A+D P S+
Sbjct: 178 SKETSLTVNKET--TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235
Query: 1794 --PT---ELSLEELSISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRK 1846
PT E + + +++ ++PTP TP +PA P TT A P+EP ++
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 1847 RKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVK 1906
+ T A ++ + + T +E A K
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKK 349
Query: 1907 FCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVT---VVPTAP-DPVPADSVQRPSDA 1962
A TPTTPK P + + P T PTAP P P +
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 1963 HTKPRPALA---AATTIITCPPSASASTLDQSKDPGP---------PRPHRPEATPSMAS 2010
+P P + TT P+ + S +K+P P P+ P T A
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 2011 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEG 2070
P+ + P+EP + + APT++ P E A T E +
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529
Query: 2071 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP 2130
KL P E + T P PT AP++ +P P +P P+ K+ P
Sbjct: 530 KLTP------TTPEKLAPTTPEKPAPTTPEELAPTT-PEEPTPTTPEEPAPTTPKA-AAP 581
Query: 2131 NMPKLVIPSAATKFPPEITVTPPTPTL------LSPKGSISEETKQ 2170
N PK P+ K P T P PT +PKG+ K+
Sbjct: 582 NTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Score = 68.2 bits (165), Expect = 9e-11
Identities = 103/505 (20%), Positives = 149/505 (29%), Gaps = 47/505 (9%)
Query: 1674 PGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPV 1733
P KV P + T A + PK+P P P P
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 1734 AMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHS--DLERTPPLLPGRPARDRGPE 1791
+ E + PT P + + T ++ P P PA +
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 1792 SRPTELSLEELSISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRKRKL 1849
PT ++P P TP +P P PA TT A P+EP +K
Sbjct: 350 PAPT----------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1850 LEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQ 1909
E T + + + + T + K
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 1910 VHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAP-DPVPADSVQRPSDAHTKPRP 1968
+ PTTPK P + P PT P +P P + KP P
Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509
Query: 1969 ALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFP 2028
P A T + P P+ P +A PE E
Sbjct: 510 T----------TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 2029 PQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASE 2088
P+EP + + APT+ A P E A T EP + + P ++ +
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE------TAP 613
Query: 2089 TQPLSSPPTAASSKAPSSGSAQPPE---GHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP 2145
T P + PT AP++ P+ K S +P P PK P+ +
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673
Query: 2146 PEITVTPPTPTLLSPKGSISEETKQ 2170
P TP P +PKG+ K+
Sbjct: 674 P---TTPKEPAPTTPKGTAPTTLKE 695
Score = 67.4 bits (163), Expect = 1e-10
Identities = 120/537 (22%), Positives = 175/537 (32%), Gaps = 65/537 (12%)
Query: 1695 SPEDGQEGLPQ-PKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP 1753
+P +E P PK+P P P P A + + KE
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP----APTTPKKPAPTTPKEPA 359
Query: 1754 RAGPTEPMDTSEATVCHSDLERTP-------PLLPGRPARDRGPESRPTELSLEELSISA 1806
P EP T+ + E P P P +PA E PT + +E + +
Sbjct: 360 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT--TPKEPAPTT 417
Query: 1807 RQQPTPLTPAQPAP-----APA----PATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGK 1857
++P+P TP +PAP AP PA TT A P+EP +++ E
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477
Query: 1858 TLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQ 1917
T K A + +E A K A
Sbjct: 478 TT-----------PKKPAPTTPKEP---------APTTPKEPAPTTTKKPAPTTPKEPAP 517
Query: 1918 RQASGDTPTTPKH-PKDSRENFFPVT---VVPTAPDPVPADSVQRPSDAHTKPRPALAAA 1973
PTTPK + E P T PT P+ + + + P+ T PA
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT-TPEEPAPTTP 576
Query: 1974 TTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPR 2033
P A T + P P+ P A P+G + E P++P
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP- 635
Query: 2034 HSPQVKMAPTSS--PAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQP 2091
+P+ ++APT++ P C G PT +E P P E + T P
Sbjct: 636 -APK-ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKE----PAPTTP 685
Query: 2092 LSSPPTAASSKAPSSGSAQPPE---GHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEI 2148
+ PT AP++ P+ K S +P P PK P+ + P
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 2149 TVTPPTPTLLSPKGSISE-ETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQE 2204
P T +P + SE T K +S E +P + LE S +E
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 802
Score = 46.6 bits (109), Expect = 3e-04
Identities = 103/476 (21%), Positives = 148/476 (31%), Gaps = 68/476 (14%)
Query: 1656 TVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQ-PKKPPLADG 1714
T K T E A + + P P T + +P +E P PKKP
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE----PAPTTPKEPAPTTPKKPAPTTP 488
Query: 1715 SGPGPE-PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR------------AGPTEPM 1761
P P P +P + A + + +P+ P +P
Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
T+ + + E P P PA + P + +E + + ++P P TP +PAP
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 1822 PAPATTTGTRAGGHP---EEPLSRLSRK--RKLLEDTESGKTLLLDAYRVWQQGQKGVAY 1876
T T G P +EP +K K L T + + + KG A
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA- 665
Query: 1877 DLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRE 1936
+E A + A G PTT K P
Sbjct: 666 ----------------PTTPKEPAPTTPKE--------PAPTTPKGTAPTTLKEPA---- 697
Query: 1937 NFFPVTVVPTAPDPVPADSVQRP-SDAHTKPRPALAAATTIITCPPSASASTLDQSKDPG 1995
P T AP + + + P S KP P T T P A T K P
Sbjct: 698 ---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPT--TPKKPA 750
Query: 1996 PPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAE 2055
P P P T S S +E + + E P K A +SP EP +
Sbjct: 751 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTK 809
Query: 2056 AALGTGAEPTCSQEGK-----LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS 2106
T E T + + K LR P A + ET + T + A ++
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 865
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 71.6 bits (174), Expect = 8e-12
Identities = 123/547 (22%), Positives = 188/547 (34%), Gaps = 72/547 (13%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR 1754
+P +E P K+P P P K + A + + KE
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSP 475
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPE----SRPTELSLEELSISARQQP 1810
P EP T+ + + E P P + P P + +E + + ++P
Sbjct: 476 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 535
Query: 1811 TPLTPAQPAPA----PAPATTTGTRAGGHPEEPLSRLSRKR-----KLLEDTESGKTLLL 1861
P TP +PAP PAP TTT A P+EP ++ K L T K
Sbjct: 536 APTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594
Query: 1862 DAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
+ + +A EE + AAA
Sbjct: 595 TPEKPAPTTPEELA-----------------PTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 1922 GDTPTTPKHPKDSREN----FFPVTVVPTAPDPVPADSVQRPS-DAHTKPRPALAAATTI 1976
PTTPK P + P PT P +++ P+ KP P A TT
Sbjct: 638 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697
Query: 1977 -----ITC----PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSF 2027
TC P + + K+P P P P T P+G + E
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT------PKGTAPTTLKEPAPT 751
Query: 2028 PPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAE--PTCSQEGKLRPEPRRDGEAQEA 2085
P++P +P+ ++APT++ + A T E PT +E P P +
Sbjct: 752 TPKKP--APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPT 804
Query: 2086 ASETQP--LSSPPTAASSKAPSSGSAQPPEGHP---GKPEPSRAKSRPL-PNMPKLVIPS 2139
ET P S T ++K P++ P E P +P P ++ P P +P P
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP- 863
Query: 2140 AATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLE 2199
AATK PE+T T T + E T K +A + + + +V
Sbjct: 864 AATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 921
Query: 2200 TSSQESS 2206
T++Q+++
Sbjct: 922 TTTQDTT 928
Score = 70.1 bits (170), Expect = 2e-11
Identities = 124/572 (21%), Positives = 196/572 (34%), Gaps = 79/572 (13%)
Query: 1661 EDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPK---KPPLADGSGP 1717
E + S + S K+ + ++ K +D ++ + K KPP+ D +G
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Query: 1718 GPEPG--------------GKVGL---------LNHRPVAMDAGDSADQSGERKDKESPR 1754
G + G KV +N RP D++ ++ +KE+
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET-- 241
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPL-----LPGRPARDRGPESR----PT---ELSLEEL 1802
T+ T+ E+T + A+D P S+ PT E + +
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 301
Query: 1803 SISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL 1860
+++ ++PTP TP +PA P TT A P+EP ++ + T
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 1861 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA 1920
A ++ + + T +E A K A
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTP 415
Query: 1921 SGDTPTTPKHPKDSRENFFPVT---VVPTAP-DPVPADSVQRPSDAHTKPRPALA---AA 1973
TPTTPK P + + P T PTAP P P + +P P +
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475
Query: 1974 TTIITCPPSASASTLDQSKDPGP---------PRPHRPEATPSMASLGPEGEELARVAEG 2024
TT P+ + S +K+P P P+ P T A P+ +
Sbjct: 476 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 535
Query: 2025 TSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQE 2084
P+EP + + APT++ P E A T E + KL P E
Sbjct: 536 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP------TTPE 589
Query: 2085 AASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKF 2144
+ T P PT AP++ +P P +P P+ K+ PN PK P+ K
Sbjct: 590 KLAPTTPEKPAPTTPEELAPTT-PEEPTPTTPEEPAPTTPKA-AAPNTPKEPAPT-TPKE 646
Query: 2145 PPEITVTPPTPTL------LSPKGSISEETKQ 2170
P T P PT +PKG+ K+
Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678
Score = 46.6 bits (109), Expect = 3e-04
Identities = 103/476 (21%), Positives = 148/476 (31%), Gaps = 68/476 (14%)
Query: 1656 TVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQ-PKKPPLADG 1714
T K T E A + + P P T + +P +E P PKKP
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE----PAPTTPKEPAPTTPKKPAPTTP 540
Query: 1715 SGPGPE-PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR------------AGPTEPM 1761
P P P +P + A + + +P+ P +P
Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
T+ + + E P P PA + P + +E + + ++P P TP +PAP
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 1822 PAPATTTGTRAGGHP---EEPLSRLSRK--RKLLEDTESGKTLLLDAYRVWQQGQKGVAY 1876
T T G P +EP +K K L T + + + KG A
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA- 717
Query: 1877 DLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRE 1936
+E A + A G PTT K P
Sbjct: 718 ----------------PTTPKEPAPTTPKE--------PAPTTPKGTAPTTLKEPA---- 749
Query: 1937 NFFPVTVVPTAPDPVPADSVQRP-SDAHTKPRPALAAATTIITCPPSASASTLDQSKDPG 1995
P T AP + + + P S KP P T T P A T K P
Sbjct: 750 ---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPT--TPKKPA 802
Query: 1996 PPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAE 2055
P P P T S S +E + + E P K A +SP EP +
Sbjct: 803 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTK 861
Query: 2056 AALGTGAEPTCSQEGK-----LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS 2106
T E T + + K LR P A + ET + T + A ++
Sbjct: 862 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 917
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 71.6 bits (174), Expect = 8e-12
Identities = 123/547 (22%), Positives = 188/547 (34%), Gaps = 72/547 (13%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR 1754
+P +E P K+P P P K + A + + KE
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE---PAPTTPKEPAPTTTKEPSP 516
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPE----SRPTELSLEELSISARQQP 1810
P EP T+ + + E P P + P P + +E + + ++P
Sbjct: 517 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 576
Query: 1811 TPLTPAQPAPA----PAPATTTGTRAGGHPEEPLSRLSRKR-----KLLEDTESGKTLLL 1861
P TP +PAP PAP TTT A P+EP ++ K L T K
Sbjct: 577 APTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 635
Query: 1862 DAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
+ + +A EE + AAA
Sbjct: 636 TPEKPAPTTPEELA-----------------PTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 1922 GDTPTTPKHPKDSREN----FFPVTVVPTAPDPVPADSVQRPS-DAHTKPRPALAAATTI 1976
PTTPK P + P PT P +++ P+ KP P A TT
Sbjct: 679 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738
Query: 1977 -----ITC----PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSF 2027
TC P + + K+P P P P T P+G + E
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT------PKGTAPTTLKEPAPT 792
Query: 2028 PPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAE--PTCSQEGKLRPEPRRDGEAQEA 2085
P++P +P+ ++APT++ + A T E PT +E P P +
Sbjct: 793 TPKKP--APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPT 845
Query: 2086 ASETQP--LSSPPTAASSKAPSSGSAQPPEGHP---GKPEPSRAKSRPL-PNMPKLVIPS 2139
ET P S T ++K P++ P E P +P P ++ P P +P P
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP- 904
Query: 2140 AATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLE 2199
AATK PE+T T T + E T K +A + + + +V
Sbjct: 905 AATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 962
Query: 2200 TSSQESS 2206
T++Q+++
Sbjct: 963 TTTQDTT 969
Score = 70.1 bits (170), Expect = 2e-11
Identities = 124/572 (21%), Positives = 196/572 (34%), Gaps = 79/572 (13%)
Query: 1661 EDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPK---KPPLADGSGP 1717
E + S + S K+ + ++ K +D ++ + K KPP+ D +G
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Query: 1718 GPEPG--------------GKVGL---------LNHRPVAMDAGDSADQSGERKDKESPR 1754
G + G KV +N RP D++ ++ +KE+
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET-- 282
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPL-----LPGRPARDRGPESR----PT---ELSLEEL 1802
T+ T+ E+T + A+D P S+ PT E + +
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 342
Query: 1803 SISARQQPTPLTPAQPAPAPA--PATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL 1860
+++ ++PTP TP +PA P TT A P+EP ++ + T
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 1861 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA 1920
A ++ + + T +E A K A
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPT------TPKEPAPTTPKKPAPTTPKEPAPTTP 456
Query: 1921 SGDTPTTPKHPKDSRENFFPVT---VVPTAP-DPVPADSVQRPSDAHTKPRPALA---AA 1973
TPTTPK P + + P T PTAP P P + +P P +
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516
Query: 1974 TTIITCPPSASASTLDQSKDPGP---------PRPHRPEATPSMASLGPEGEELARVAEG 2024
TT P+ + S +K+P P P+ P T A P+ +
Sbjct: 517 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 576
Query: 2025 TSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQE 2084
P+EP + + APT++ P E A T E + KL P E
Sbjct: 577 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP------TTPE 630
Query: 2085 AASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKF 2144
+ T P PT AP++ +P P +P P+ K+ PN PK P+ K
Sbjct: 631 KLAPTTPEKPAPTTPEELAPTT-PEEPTPTTPEEPAPTTPKA-AAPNTPKEPAPT-TPKE 687
Query: 2145 PPEITVTPPTPTL------LSPKGSISEETKQ 2170
P T P PT +PKG+ K+
Sbjct: 688 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
Score = 46.6 bits (109), Expect = 3e-04
Identities = 103/476 (21%), Positives = 148/476 (31%), Gaps = 68/476 (14%)
Query: 1656 TVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQ-PKKPPLADG 1714
T K T E A + + P P T + +P +E P PKKP
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE----PAPTTPKEPAPTTPKKPAPTTP 581
Query: 1715 SGPGPE-PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR------------AGPTEPM 1761
P P P +P + A + + +P+ P +P
Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
T+ + + E P P PA + P + +E + + ++P P TP +PAP
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN--TPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 1822 PAPATTTGTRAGGHP---EEPLSRLSRK--RKLLEDTESGKTLLLDAYRVWQQGQKGVAY 1876
T T G P +EP +K K L T + + + KG A
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA- 758
Query: 1877 DLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRE 1936
+E A + A G PTT K P
Sbjct: 759 ----------------PTTPKEPAPTTPKE--------PAPTTPKGTAPTTLKEPA---- 790
Query: 1937 NFFPVTVVPTAPDPVPADSVQRP-SDAHTKPRPALAAATTIITCPPSASASTLDQSKDPG 1995
P T AP + + + P S KP P T T P A T K P
Sbjct: 791 ---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPT--TPKKPA 843
Query: 1996 PPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAE 2055
P P P T S S +E + + E P K A +SP EP +
Sbjct: 844 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTK 902
Query: 2056 AALGTGAEPTCSQEGK-----LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS 2106
T E T + + K LR P A + ET + T + A ++
Sbjct: 903 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 958
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 70.9 bits (172), Expect = 1e-11
Identities = 72/249 (28%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 1929 KHPKDSRENFFPVTVVPTAPDPV-PADSVQRPSDAHTKPRPALAAATTIITCPPSASAST 1987
K P + + P T + PV P ++ P ++ + + ATT PPS +
Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 1988 LDQSKDPGPPR----PHRPEATPSMASL-----GPE--GEELARVAEGTSFPPQEPRHSP 2036
+ P P+ P + TPS+ +L GP + A TS P++ R +P
Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925
Query: 2037 QVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPP 2096
AP PA P P A A P + G P P+ AA+ P P
Sbjct: 926 ----APKGIPASPS--PKGAPTPPAATPPSPKGGPATPSPKW-APTPPAATPPSPKGGPA 978
Query: 2097 TAASSKAPSSGSAQPP--EGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPT 2154
T + AP+ +A PP +G P P P A + P P AAT FP + TPP
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS-TPPA 1037
Query: 2155 PTLLSPKGS 2163
T SPKGS
Sbjct: 1038 ATPPSPKGS 1046
Score = 63.5 bits (153), Expect = 2e-09
Identities = 132/586 (22%), Positives = 178/586 (30%), Gaps = 104/586 (17%)
Query: 1669 EGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLL 1728
EG P PK P MT+ KA +G+P P A P K G
Sbjct: 898 EGPATPAPKQA--PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955
Query: 1729 NHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDR 1788
P +A SP+ GP P T + TPP G PA
Sbjct: 956 TPSPKWAPTPPAATPP-------SPKGGPATPSPKGAPTPPAA----TPPSPKGGPATP- 1003
Query: 1789 GPESRPTELSLEELSISARQQPTPLTP-AQPAPAPAPATTTGTRAGGHPEEPLSRLSRKR 1847
P+ PT ++ TP +P PA P P + A P S +
Sbjct: 1004 SPKGAPTPPAV-----------TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 1848 KLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKF 1907
T TL KG T L AA + K
Sbjct: 1053 PKGAPTTPAATL---------PSPKGGP-----------ATPSLKGAPTPPAATPPSPKG 1092
Query: 1908 CQVHLGAAAQRQASGDTPTTPKHPKDSRENF-FPVTVVPTAPDPVPADSVQRPSDAHTKP 1966
TP +PK + + P T T P P + P A T P
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152
Query: 1967 RPALAAATTIITCPPSASASTLDQSKDPGP------PRPHRPEATPSMASLGPEGEELAR 2020
+ + PP A T + P P P P TP+ P+G
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 2021 VAEGTSFPPQEPRHSPQVKMA---PTSSPAEPHCWPAEAALGTGAEPTC----------- 2066
+G P SP+ +A P +P P P G P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 2067 SQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQP--PEGHPGKPEPSRA 2124
S +G L P + + P P T+ AP+ +A P P+G PG P P A
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 2125 KSRP--LPNMPKLVIPSAAT----------------KFPPEIT--------VTPPT---- 2154
+ P P PK AT PP T +TPP+
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 2155 PTLLSPKG-----SISEETKQKLKSAILSAQSAANVRKESLCQPAL 2195
P + SPKG ++ + +K + ++ + AA K L PA+
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Score = 63.2 bits (152), Expect = 3e-09
Identities = 120/485 (24%), Positives = 160/485 (32%), Gaps = 100/485 (20%)
Query: 1704 PQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQS-GERKDKESPRAGPTEPMD 1762
PQ K+PP GS GP+ +G L+ ++A + S + K+SP
Sbjct: 803 PQTKRPPTKKGSA-GPDT--PIGNLSSPVSPVEASFLPENSLSFQGSKDSP--------- 850
Query: 1763 TSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAP 1822
HS TPP G P S T LS + +++ ++ PTP P P
Sbjct: 851 ----ATTHSP---TPPSPKGAPT-----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE 898
Query: 1823 APATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVE 1882
PAT +A LS S K T + K + KG
Sbjct: 899 GPATPAPKQA-----PALSMTSSSPKKARATPAPKGIPA------SPSPKGAP------- 940
Query: 1883 RIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTP--TTPKHPKDSRENFFP 1940
AA + K G A TP TP PK P
Sbjct: 941 -------------TPPAATPPSPKG-----GPATPSPKWAPTPPAATPPSPKGG-----P 977
Query: 1941 VTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP-----PSAS-----ASTLDQ 1990
T P PA + P P P A +T P P+A+ AST
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 1991 SKDPGP-------PRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPT 2043
+ P P P P TP+ P+G +G PP SP+
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK------ 1091
Query: 2044 SSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKA 2103
PA P P A + A P S +G L P + AA+ P T A
Sbjct: 1092 GGPATPS--PKGAPMPPAATPP-SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 2104 PSSGSAQP--PEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP-PEITVTPPTPTLLSP 2160
P++ +A P P+G P P A + P P P P P+ T P T SP
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSP 1205
Query: 2161 KGSIS 2165
KG ++
Sbjct: 1206 KGGLA 1210
Score = 62.4 bits (150), Expect = 5e-09
Identities = 118/538 (21%), Positives = 182/538 (33%), Gaps = 54/538 (10%)
Query: 1674 PGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPV 1733
P PK G PG K +P P PK P + P + G P
Sbjct: 1318 PSPK--GSPGTPPP-----KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
Query: 1734 AMDAGDSADQSGERKDKESPRAGPTEPMDTSEAT------VCHSDLERTPPLLPGRPARD 1787
A + + G SP+ GP P + T + TP G
Sbjct: 1371 P-PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429
Query: 1788 RGPESRP--TELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT-RAGGHPEEPLSRLS 1844
+G + P T +SL++ ++ + P TP+ PA T + + P++ + S
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 1845 RKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQA 1904
K+ G L + ++ A R + I +L K+ A ++A
Sbjct: 1490 PKKAPATPAPMGAPTLPAV--IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 1905 VKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPT----APDPV-----PADS 1955
+ + + + + A P P S+E P V P+ AP P PA +
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPS-SKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606
Query: 1956 VQRPSDAHTKPR---------PALAAATTIITCPPSASASTLDQSKDP-------GPPRP 1999
P +A T P PA A T PP +S D P G P
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666
Query: 2000 HRPEATPSMASLGPEGEELARVA---EGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEA 2056
+ P A GP + VA E T R PQ K + +SP P C A
Sbjct: 1667 QASKGLP--AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPDPSA 1722
Query: 2057 ALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHP 2116
G+ + L P + + + + P SKA + +A E
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
Query: 2117 GKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLL--SPKGSISEETKQKL 2172
KPE + + P P + + PS PP+ P +P L+ SP ++ + +L
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Score = 58.5 bits (140), Expect = 7e-08
Identities = 133/559 (23%), Positives = 183/559 (32%), Gaps = 53/559 (9%)
Query: 1671 SERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNH 1730
S + GP L GA T + SP+ G P PK P+ + P P P G + H
Sbjct: 1066 SPKGGPATPSLKGAP-TPPAATPPSPKGGP-ATPSPKGAPMPPAATP-PSPKGGLATPPH 1122
Query: 1731 RPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGP 1790
+ + P+ PT P T + L PP G P P
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP--KGGLATPPP--KGAPTT---P 1175
Query: 1791 ESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLL 1850
+ P + S + PT TPA P+P T + G + S K L
Sbjct: 1176 AATPPSPKGGLATPSPKGAPT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 1851 EDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYML---IKQVDEEAALEQAVKF 1907
+ G A +G G + L + + A AV
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 1908 CQVHLGAAAQRQASG-DTP--TTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHT 1964
G A G TP TP PK S P PT P P P+ T
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 1965 KPRPALAAATTIITCPPSASASTLDQSKDPG--PPRPHRPEATPS---------MASLGP 2013
P T P+ A+T P PP P R A PS + L P
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 2014 EGEELARVA-EGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKL 2072
+ V EG + P + P V P S P A G A P+ + L
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAV--TPVSLKKAP---ATSAPKGGPATPSSKGDPTL 1467
Query: 2073 R----PEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQP--PEGHPGKPEPSRAKS 2126
P P+ ++ A+ + P +P T A AP+ + P P+ P P R
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 2127 RPLPNM-----PKLVIPSAATKFPPEITVTPP--TPTLLSPKGSISEETKQKLKS---AI 2176
P + P + P A PP +TV P TP + +PK + + + ++ S
Sbjct: 1528 APTATLLSKKTPATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 2177 LSAQSAANVRKESLCQPAL 2195
S A KE L PA+
Sbjct: 1587 PSTYKGAPSPKELLIPPAV 1605
Score = 57.8 bits (138), Expect = 1e-07
Identities = 125/529 (23%), Positives = 163/529 (30%), Gaps = 102/529 (19%)
Query: 1670 GSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLN 1729
G P PK G P TT + SP+ G P PK P + P P K GL
Sbjct: 1162 GLATPPPK--GAP----TTPAATPPSPKGGL-ATPSPKGAPTTPAATP---PSPKGGLAT 1211
Query: 1730 HRPVAMDAGDSADQSGERKD--KESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARD 1787
P +A + SP+ PT P TPP G PA
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-------------ATPPSPKGGPATP 1258
Query: 1788 RGPESRPTELSLEELSISA-------RQQPTPLTPAQPAP-----------APAPATTTG 1829
P+ PT + S+ + P P P+P AP P T
Sbjct: 1259 P-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 1830 TRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETY 1889
G P P + + + T L A +G T
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG---------------GPTT 1362
Query: 1890 MLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKH----PKDSRENFFPVTVVP 1945
K+ A + H G A TP +PK P + P V+P
Sbjct: 1363 PSSKEGPTPPAATPS------HKGGPAM------TPPSPKRGPAIPSPKGDPTSPA-VIP 1409
Query: 1946 TAPDPVPADSVQRPSDAHTKPRPALAAATTII-------TCPPSASASTLDQSKDPG--- 1995
+P PA V R A A T + T P +T DP
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 1996 --PPRPHRPEATPSMA-SLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCW 2052
PP P P A +A S P+ G P SP+ A SS +P
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA- 1528
Query: 2053 PAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPP 2112
P L T + + L P ++ + P +P T SSK SS A P
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP-SSKEASSPPAVTP 1587
Query: 2113 EGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPK 2161
+ G P P +L+IP A T P+ TPP T SP+
Sbjct: 1588 STYKGAPSPK-----------ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Score = 38.1 bits (87), Expect = 0.097
Identities = 112/508 (22%), Positives = 172/508 (33%), Gaps = 74/508 (14%)
Query: 1752 SPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPT 1811
SP+ P P S +PP + P+ +G S P EL + S +
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVT--PSTYKGAPS-PKELLIPPAVTSPSPKEA 1613
Query: 1812 PLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQ 1871
P PA P+P T G P++ S K + S ++ Q
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK----DSPTSPASVTCKMGATVPQAS 1669
Query: 1872 KGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHP 1931
KG+ G +K+V A E +++S +P P
Sbjct: 1670 KGLPAKKGPT---------ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 1932 KDSRENFFPVTVVPTAP-DPVPADS--VQRPSDAHTKPRPALA----AATTIITC----- 1979
+ P++ V AP PV DS + DA P+ LA A+T +T
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 1980 ----PPSASAS-------TLDQSKDPGPPRPHRPEATPSMASLGPE--GEELARVAEGTS 2026
P SAS S +L + P P P + + PS L E + LA E
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Query: 2027 FP--PQEP-----------RHSPQVKMA----PTSSPAEPHCWPAEAALGTGAEPTCSQE 2069
P P EP + P K A PT S +P + G+G E S
Sbjct: 1841 LPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP---VTKNNKGSGTE---SDS 1894
Query: 2070 GKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPL 2129
+ PE Q + TQ A + P S + Q + S+ R +
Sbjct: 1895 DESVPELEEQDSTQ---ATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951
Query: 2130 PNMPKLVIPSAATKF----PPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANV 2185
+ ++ I + P++ +P + T + + E+ Q+ A L+A V
Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQ---AQLAAAEKFKV 2008
Query: 2186 RKESLCQPALEVLETSSQESSLESETDE 2213
+ E++ + QE S E E DE
Sbjct: 2009 QGEAVSNIQENTQTPTVQEESEEEEVDE 2036
Score = 35.0 bits (79), Expect = 0.82
Identities = 58/259 (22%), Positives = 90/259 (34%), Gaps = 32/259 (12%)
Query: 1925 PTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTK---PRPALAAATTIITCPP 1981
P PK P + V P PD P D PS K + ++ P
Sbjct: 487 PVAPKEPSTQVATTLRIPVSPPLPD--PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544
Query: 1982 SASASTLDQSKDPG--PPRPHRPEATPSMAS--------LGPEGEELARVAEGTSFPPQE 2031
S + + L KDP P P+ +PS S L PE LA+ + G P +
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEA-TLAKKSLGEPLPIGK 603
Query: 2032 PRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPE----PRRDGEAQEAAS 2087
P S + SS + ++ G + + + P P + A
Sbjct: 604 PASSMTSPLGVNSSAS---VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 2088 ETQPLSSPPTAASSKAPSSGSAQPPEGHPGKP--------EPSRAKSRPL-PNMPKLVIP 2138
T +S T +S + P+ HP K P+ +++ P+ P+ P
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 2139 SAATKFPPEITVTPPTPTL 2157
A PEI + P+P+L
Sbjct: 721 LATLVLAPEIPKSVPSPSL 739
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 67.4 bits (163), Expect = 1e-10
Identities = 61/239 (25%), Positives = 80/239 (33%), Gaps = 17/239 (7%)
Query: 1925 PTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSD----AHTKPRPALAAATTIITCP 1980
PTT P S P T P+ P P+ PS T P + T
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
P AS +TL + P PP P+ P + T+ PP P
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT-- 1567
Query: 2041 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQP---LSSPPT 2097
T++ P P+ T + PT + P P + T P SPPT
Sbjct: 1568 --TTTTPPPTTTPSPPTTTTPSPPTIT---TTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622
Query: 2098 AASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPT 2156
P+S + PP P P P+ + P P P+ T PP T T P PT
Sbjct: 1623 TTPITPPTSTTTLPPTTTP-SPPPTTTTTPPPTTTPS--PPTTTTPSPPITTTTTPPPT 1678
Score = 57.4 bits (137), Expect = 2e-07
Identities = 56/242 (23%), Positives = 80/242 (33%), Gaps = 23/242 (9%)
Query: 1924 TPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAAT--TIITCPP 1981
T TTP T P P P S T P P + T PP
Sbjct: 1428 TTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP 1487
Query: 1982 SASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMA 2041
+ + +T + P PP S +L P T PP +P
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPASTTTLPP---------TTTPSPPTTTTTTP----P 1534
Query: 2042 PTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLS---SPPTA 2098
PT++P+ P P T P + P P + + P + SPPT
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPS---PPPTTTTTPPPTTTPSPPTTTTPSPPTI 1591
Query: 2099 ASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLL 2158
++ P + + PP P P+ S P + P++ T PP T +PP T
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPSP--PTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649
Query: 2159 SP 2160
+P
Sbjct: 1650 TP 1651
Score = 56.2 bits (134), Expect = 3e-07
Identities = 59/240 (24%), Positives = 80/240 (33%), Gaps = 25/240 (10%)
Query: 1926 TTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASA 1985
TTP P S P T P P P + P T P P TT PP+ +
Sbjct: 1544 TTPITPPTSTTTLPPTTT----PSPPPTTTTTPPPT--TTPSPP----TTTTPSPPTITT 1593
Query: 1986 STLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMA---P 2042
+T + P PP P+ P + T+ PP P P
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653
Query: 2043 TSSPAEPHCWPAEAALGTGAEP--TCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS 2100
T++P+ P + T P T + + P S T SSP T +
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713
Query: 2101 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
+ + S+ + PP P P+ S P M T PP T +P T T L P
Sbjct: 1714 TPS-STTTPSPPPTTMTTPSPTTTPSPPTTTM---------TTLPPTTTSSPLTTTPLPP 1763
Score = 54.7 bits (130), Expect = 1e-06
Identities = 55/200 (27%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 1975 TIITCPPSASASTLDQSKDPGPPRPHR----PEATPS----MASLGPEGEELARVAEGTS 2026
T PP S +TL + P PP P TPS + P + T+
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT 1462
Query: 2027 FPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAA 2086
PP SP PT++P+ P P+ T P + P P A
Sbjct: 1463 TPPPTTTPSP-----PTTTPSPPTTTPSPPTTTTTTPPPTT-----TPSPPTTTPITPPA 1512
Query: 2087 SET----QPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP--LPNMPKLVIPSA 2140
S T SPPT ++ P + + PP P P S P P+ P P+
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP----PTT 1568
Query: 2141 ATKFPPEITVTPPTPTLLSP 2160
T PP T +PPT T SP
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSP 1588
Score = 54.3 bits (129), Expect = 1e-06
Identities = 52/240 (21%), Positives = 76/240 (31%), Gaps = 25/240 (10%)
Query: 1925 PTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSAS 1984
PTT P + P T P+ P P T P T PP +
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPI----------TPPTSTTTLPPTTTPSPPPTT 1568
Query: 1985 ASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTS 2044
+T + P PP P + P + T+ PP SP PT+
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-----PTT 1623
Query: 2045 SPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSS---PPTAASS 2101
+P P + L P+ P P + + P+++ PP +
Sbjct: 1624 TPITPPT--STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681
Query: 2102 KAPSSGSAQPPEGHPGKPEPSRAKSRPL-----PNMPKLVIPSAATKFPPEITVTPPTPT 2156
+P + + PP P P+ S P+ P+ P T P T TP PT
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741
Score = 52.4 bits (124), Expect = 5e-06
Identities = 62/263 (23%), Positives = 88/263 (33%), Gaps = 48/263 (18%)
Query: 1925 PTTPKHPKDSRENFFPVTVVPTAPDPVP------------ADSVQRPSDAHTKPRPALAA 1972
PTT P + P T P+ P P + P+ T P P
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP 1539
Query: 1973 A---TTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPP 2029
+ TT IT P S +TL + P PP P+ P + T+ PP
Sbjct: 1540 SPPTTTPIT--PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597
Query: 2030 QEPRHSPQVKMA----PTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEA 2085
SP PT++P+ P P T P + P P
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS---PPP--------T 1646
Query: 2086 ASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP 2145
+ T P ++ P+ ++ PS PP P P+ S P+ P P
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPS-----PPITTTTTPPPTTTPSSPITTTPS----------P 1691
Query: 2146 PEITVTPPTPTLLSPKGSISEET 2168
P T+T P+PT +P I+ T
Sbjct: 1692 PTTTMTTPSPT-TTPSSPITTTT 1713
Score = 42.0 bits (97), Expect = 0.007
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 18/118 (15%)
Query: 2051 CWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQ 2110
CWP + + T + PT + P P + T SPPT ++ P + +
Sbjct: 1389 CWPMDKCITTPSPPTTT------PSPPPTSTTTLPPTTTP---SPPTTTTTTPPPTTTPS 1439
Query: 2111 PPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEET 2168
PP P P+ S P+ S T PP T +PPT T P + S T
Sbjct: 1440 PPITTTTTPPPTTTPSPPI---------STTTTPPPTTTPSPPTTTPSPPTTTPSPPT 1488
Score = 41.2 bits (95), Expect = 0.011
Identities = 60/270 (22%), Positives = 87/270 (32%), Gaps = 28/270 (10%)
Query: 1924 TPTTPKHPKDSRENFFPVTVVPTA-PDPVPADSVQRPSDAHTKPRPALAAATTIITCPPS 1982
TPT + P + P+T T P P P + + T T T P+
Sbjct: 4051 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4105
Query: 1983 AS--ASTLDQSKDPGPPRPHRPEATPSMASLG------PEGEELARVAEGTSFPPQEPRH 2034
+ +T + P P P TP + P G + T+ P
Sbjct: 4106 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4165
Query: 2035 SPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQ---- 2090
+P PT++P T PT + G P A A T
Sbjct: 4166 TPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216
Query: 2091 PLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITV 2150
S+P T+ S+ +P + S P E + P P PP T
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT 4276
Query: 2151 TPP-TPTLLSPKGSISEETKQKLKSAILSA 2179
+PP TPT + GS S T +++ SA
Sbjct: 4277 SPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 64.7 bits (156), Expect = 1e-09
Identities = 116/501 (23%), Positives = 177/501 (35%), Gaps = 60/501 (11%)
Query: 1707 KKPPLADGSGPGP--EPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP--RAGPTE-PM 1761
++ P A + PGP PG G P+ Q G R E R TE P
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLG--------QKGLRISAEETVARGKATEAPK 152
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
++ + D P P PA R + TE+ L + SAR +P P + +
Sbjct: 153 RSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 1822 --------PAPATTTGTRAGGHPEEPLSRL--SRKRKLLEDTESGKTLLLDAYRVWQQGQ 1871
P+PA AGG + P SR S L SG + R +
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-----RGTPRAP 266
Query: 1872 KGVAYDLGRVERIMSETYMLIKQVDEEAALE--QAVKFCQVHLGAAAQRQASGDTPTTPK 1929
+ + + + + + D AL + AA Q QA P TP
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 1930 HPKDSRENFFPVTVVPTAPDP------VPADSVQRPSDAHTK-PRPALAAATTIITCPPS 1982
+ + P+ + P +P +P+ PS A T P L A + + PP
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 1983 ASASTLDQSKDPG---PP--RPHRPEATPSMASLG-PEGEELARVAEGTSFPPQEPRHSP 2036
+ +T P PP P P A+P ++ L P + +A P P SP
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446
Query: 2037 QVKMA---PTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLS 2093
V+ P S P P P A + A P P A PL+
Sbjct: 447 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 2094 SPPTAASS---KAPSSGSAQPPEGHPGKPE--PSRAKSRPLPNMPKLVIPSAATKFPP-- 2146
+PP + +AP + + P + P P P +A P ++P + + + PP
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 2147 -----EITVTPP-TPTLLSPK 2161
++ +PP +PTL +P+
Sbjct: 567 AAPLLQVPPSPPASPTLQAPR 587
Score = 57.4 bits (137), Expect = 2e-07
Identities = 131/531 (24%), Positives = 177/531 (33%), Gaps = 154/531 (29%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPG---------GKVGLLNHRPVAMDAGDSADQSG 1745
+P GL P+ P P P P G G + +P+A AG G
Sbjct: 16 TPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG---G 67
Query: 1746 ERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSIS 1805
+ +PRAGPT TS R P P PA RG + P + +
Sbjct: 68 ATIPESAPRAGPTRSAGTSS---------RNPASRP--PASGRGERAPPAKNT------- 109
Query: 1806 ARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYR 1865
P P +P +GT G PL
Sbjct: 110 -----------SPGPVSSPGRASGTTRPG----PL------------------------- 129
Query: 1866 VWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTP 1925
GQKG+ RI +E + + EA A L A A+R SG TP
Sbjct: 130 ----GQKGL--------RISAEE-TVARGKATEAPKRSA-------LSAGARRDTSGPTP 169
Query: 1926 TTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPP---- 1981
TP P +R + T V P P P+ + P++ PR ++++A+ T P
Sbjct: 170 GTPS-PAMARRSRAAGTEV-GLPRPAPSARPRPPTEG---PRKSVSSASEHSTTEPSPAA 224
Query: 1982 ------------------SASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAE 2023
S+SA+ L GP P A + P+G + R
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR--- 281
Query: 2024 GTSFPPQ--EPRHSPQVKMAPTSSPAEPHCWPA-EAALGTGAEP-----------TCSQE 2069
PPQ PR + P SS P P+ AAL + A P TC
Sbjct: 282 ----PPQVTPPRKDAAPALGPLSS--SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335
Query: 2070 GKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS-GSAQPPEGHPGKPEPSRAKSRP 2128
L P + A Q L SPP S+A +S GS H P P + P
Sbjct: 336 TPLPLAP----PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS---P 388
Query: 2129 LPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSA 2179
L P P+ A P + +PP LSP + S + L +L A
Sbjct: 389 LATPPPQAPPALALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 438
Score = 48.5 bits (114), Expect = 7e-05
Identities = 63/238 (26%), Positives = 83/238 (34%), Gaps = 36/238 (15%)
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEG-------EELARVAEGTSFPPQEPR 2033
P+A A L + PG PRP P ++ LG G E A G + P PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 2034 HSPQVKMAPTSS-------PAEPHCWPAEAALGTGAEPTCS---QEGKLRPEPRRDGEAQ 2083
P + A TSS PA A A T P S G RP P +
Sbjct: 77 AGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 2084 EAASETQPLSSPPTAASSKAPSSGSAQPPEG-HPGKPEPSRAK-----------SRPLPN 2131
+A ET A A S+G+ + G PG P P+ A+ RP P+
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
Query: 2132 ---MPKLVIPSAATKFPPEITVTPPTPTLL---SPKGSISEETKQKLKSAILSAQSAA 2183
P P + E + T P+P S G + + L S+ S A
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Score = 32.0 bits (71), Expect = 6.9
Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 33/164 (20%)
Query: 1704 PQPKKPPLADGSGP--GPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPM 1761
P P PP S GP+ G P + DS + G A + P
Sbjct: 609 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG---------AAASPPP 659
Query: 1762 DTSEATVCHS---DLERTPPL---------LPGRPARDRGPESRPTELSLEELSISARQQ 1809
D +E CH PPL LP PA GP S ++ E +
Sbjct: 660 D-AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYET-----EG 711
Query: 1810 PTPLTPAQPA--PAPAPATTTGTRAGGHPEEPLSRLSRKRKLLE 1851
P TPA A P P+P T+ G A G SR ++ +L E
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 63.9 bits (154), Expect = 2e-09
Identities = 127/531 (23%), Positives = 178/531 (33%), Gaps = 144/531 (27%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSGPGPEPG---------GKVGLLNHRPVAMDAGDSADQSG 1745
+P GL P+ P P P P G G + +P+A AG G
Sbjct: 16 TPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG---G 67
Query: 1746 ERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSIS 1805
+ +PRAGPT TS R P P PA RG + P + +
Sbjct: 68 ATIPESAPRAGPTRSAGTSS---------RNPASRP--PASGRGERAPPAKNT------- 109
Query: 1806 ARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYR 1865
P P +P +GT G PL
Sbjct: 110 -----------SPGPVSSPGRASGTTRPG----PL------------------------- 129
Query: 1866 VWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTP 1925
GQKG+ RI +E + + EA A L A A+R SG TP
Sbjct: 130 ----GQKGL--------RISAEE-TVARGKATEAPKRSA-------LSAGARRDTSGPTP 169
Query: 1926 TTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASA 1985
TP P +R + T V P P P+ + P++ PR ++++A+ T PS +A
Sbjct: 170 GTPS-PAMARRSRAAGTEVGL-PRPAPSARPRPPTEG---PRKSVSSASEHSTTEPSPAA 224
Query: 1986 STLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSS 2045
S G RP A+ S++S AR P+ P H Q K +
Sbjct: 225 RRRP-SAGGGLQRP----ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 2046 PAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPS 2105
P P PR+D AA PLSS P A S + +
Sbjct: 280 LRPPQVTP----------------------PRKD-----AAPALGPLSSSPLATPSPSGT 312
Query: 2106 SGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSIS 2165
PP + P P+ LP P L P PP + P TL SP +
Sbjct: 313 KARPVPPPDNAATPLPA-----TLPPSPPLATPLPLA--PPSPSAPPSLQTLPSPPATPP 365
Query: 2166 EETKQKLKSAILSAQSAANV-----RKESLCQPALEVLETSSQESSLESET 2211
+ + + + A + SL P+L+ + SSL++ T
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Score = 53.5 bits (127), Expect = 2e-06
Identities = 118/504 (23%), Positives = 166/504 (32%), Gaps = 95/504 (18%)
Query: 1707 KKPPLADGSGPGP--EPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP--RAGPTE-PM 1761
++ P A + PGP PG G P+ Q G R E R TE P
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLG--------QKGLRISAEETVARGKATEAPK 152
Query: 1762 DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPA 1821
++ + D P P PA R + TE+ L + SAR +P P + +
Sbjct: 153 RSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 1822 --------PAPATTTGTRAGGHPEEPLSRL--SRKRKLLEDTESGKTLLLDAYRVWQQGQ 1871
P+PA AGG + P SR S L SG +
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA------------ 259
Query: 1872 KGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHP 1931
+G + + ++ + A + + T P P
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
Query: 1932 KDSRENFFPVTVVPTAP----------DPVPADSVQR-PSDAHTKPR--------PALAA 1972
D+ P T+ P+ P P S+Q PS T P P + A
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 1973 ATTIITCPPSASASTLDQSKDPGPPRP--------------HRPEATPSMASLGPEGEEL 2018
++ T PP +L PP P +AT S ++ P +
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 2019 ARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRR 2078
+ + S P P SP ++ AP S PA P P + +L P S L P +
Sbjct: 440 SLTSP--SRPASTPPDSPPLQ-APLSLPASP---PLQTSLSPAVSPLSSP---LTIHPLQ 490
Query: 2079 DGEAQEAASETQPLSS----PPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPK 2134
+ + S PLSS P SS AP S Q P P+ + PL N+P
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPS--LQTP--------PASLTTPPLENLPS 540
Query: 2135 LVIPSAATKFPPEIT---VTPPTP 2155
L P T P T TPP P
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCP 564
Score = 52.0 bits (123), Expect = 6e-06
Identities = 68/240 (28%), Positives = 89/240 (37%), Gaps = 30/240 (12%)
Query: 1948 PDPVPADSVQRPSDAHTKPR---PALAAATTI-ITCPPSASASTLDQSKDPG---PP--R 1998
P P+ + PS T P PALA+ + PP + +T P PP
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632
Query: 1999 PHRPEATPSMASLG-PEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAA 2057
P P A+P ++ L P + +A P P SP V+ AP S PA P P +A
Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSP--SA 689
Query: 2058 LGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASS--KAPSSGSAQPPEGH 2115
P L+ P + S T P +PP A+ + P S A PP
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749
Query: 2116 PGKPEPSRAKSRPLPNMPKLVIP---------SAATKFPPE---ITVTPPTPTLLSPKGS 2163
P P + PL P L +P S K PP+ TPP L SP S
Sbjct: 750 SATPPP---RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806
Score = 48.5 bits (114), Expect = 7e-05
Identities = 66/243 (27%), Positives = 84/243 (34%), Gaps = 40/243 (16%)
Query: 1940 PVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRP 1999
P P P P P +Q P T P P ++I T PP A + P P
Sbjct: 556 PHLETPPCPAPCP---LQAPPSPLTTPPPE--TPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 2000 HRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSP--------------QVKMAPTSS 2045
P ATP + P L + S PP P SP + AP S
Sbjct: 611 LSPLATPPPQA--PPXLALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 2046 PAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPS 2105
P P P +A A P S P +A + + PL PP+ +S P
Sbjct: 668 PPSP---PVQAPFSPPASPPVS------PSATPPSQAPPSLA-APPLQVPPSPPAS-PPM 716
Query: 2106 SGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP----PEITVTPPTPTLLSPK 2161
S SA PP P P P A +P P P + + P P + PP SP
Sbjct: 717 SPSATPP---PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Query: 2162 GSI 2164
S+
Sbjct: 774 ASL 776
Score = 39.3 bits (90), Expect = 0.044
Identities = 67/236 (28%), Positives = 88/236 (37%), Gaps = 44/236 (18%)
Query: 1925 PTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPR-----------PALAAA 1973
P+ P P S T P AP P+ A +Q P P P L AA
Sbjct: 708 PSPPASPPMSPS----ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 1974 TTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEP- 2032
+ PPS AS L S PP P+A P++A+ P + L + SFP Q P
Sbjct: 764 PPL-QVPPSPPAS-LPMSPLAKPP----PQAPPALAT--PPLQALP--SPPASFPGQAPF 813
Query: 2033 RHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPL 2092
S + M+P ++P P P AA P+ L+ PRR P
Sbjct: 814 SPSASLPMSPLATP-PPQAPPVLAAPLLQVPPSPPASPTLQ-APRR-----------PPT 860
Query: 2093 SSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEI 2148
P T+ S + A P P PSR+ S L S+AT P E+
Sbjct: 861 PGPDTSVSGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Score = 36.6 bits (83), Expect = 0.28
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 1326 SAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSD 1385
S TLP P A+ PS + P +T+PP A P + PH +P ++ S +ALS
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS-PLALSS 411
Query: 1386 SSST 1389
+T
Sbjct: 412 LQAT 415
Score = 32.0 bits (71), Expect = 6.9
Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 33/164 (20%)
Query: 1704 PQPKKPPLADGSGP--GPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPM 1761
P P PP S GP+ G P + DS + G A + P
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG---------AAASPPP 928
Query: 1762 DTSEATVCHS---DLERTPPL---------LPGRPARDRGPESRPTELSLEELSISARQQ 1809
D +E CH PPL LP PA GP S ++ E +
Sbjct: 929 D-AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYET-----EG 980
Query: 1810 PTPLTPAQPA--PAPAPATTTGTRAGGHPEEPLSRLSRKRKLLE 1851
P TPA A P P+P T+ G A G SR ++ +L E
Sbjct: 981 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 1024
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 62.8 bits (151), Expect = 4e-09
Identities = 63/251 (25%), Positives = 94/251 (37%), Gaps = 13/251 (5%)
Query: 1924 TPTTPKHPKDSRENFFPVT--VVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPP 1981
+PT+P + S ++ P + PT+P P P+ P + T+ P
Sbjct: 1700 SPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPT 1758
Query: 1982 SASASTLDQSKDPGPPR--PHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S S S S P P P P +P+ S P + + S+ P PR++PQ
Sbjct: 1759 SPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP--SYSPSSPRYTPQ-- 1814
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+PT +P+ P P+ + + P S T P SP +
Sbjct: 1815 -SPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPK 1873
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP--PEITVTPPTPTL 2157
S + S P+ P P S P PK P++ T P P+ + T PT +
Sbjct: 1874 YSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS-PTSPTYSPTSPKYSPTSPTYSP 1932
Query: 2158 LSPKGSISEET 2168
SPKGS T
Sbjct: 1933 TSPKGSTYSPT 1943
Score = 58.2 bits (139), Expect = 9e-08
Identities = 64/252 (25%), Positives = 87/252 (34%), Gaps = 42/252 (16%)
Query: 1924 TPTTPKHPKDSRENFFPVT--VVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPP 1981
+PT+P + S N+ P + PT+P P P+ + P + T+ P
Sbjct: 1735 SPTSPSYSPTS-PNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT 1793
Query: 1982 SASASTLDQSKDPGPPR--PHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S S S S P PR P P TPS S P S+ P P+++P
Sbjct: 1794 SPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP---------SYSPTSPKYTPT-- 1842
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P+ SP+ P P K P + S T P SP T
Sbjct: 1843 -SPSYSPSSPEYTPTSP--------------KYSPTSPKYSPTSPKYSPTSPTYSPTTPK 1887
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKL---------VIPSAATKFP--PEI 2148
S + S P P P+ S P PK P +T P P
Sbjct: 1888 YSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGY 1947
Query: 2149 TVTPPTPTLLSP 2160
+ T PT +L SP
Sbjct: 1948 SPTSPTYSLTSP 1959
Score = 50.8 bits (120), Expect = 1e-05
Identities = 56/246 (22%), Positives = 81/246 (32%), Gaps = 17/246 (6%)
Query: 1924 TPTTPKHPKDSRENFFPVT--VVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPP 1981
+PT+P + S + P + PT+P P P+ + P + T+ P
Sbjct: 1594 SPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPT 1653
Query: 1982 SASASTLDQSKDPGPPR--PHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S S S S P P P P +P+ S P S+ P P +SP
Sbjct: 1654 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP---------SYSPTSPSYSP--- 1701
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P+ SP P P + + P S T P +P + +
Sbjct: 1702 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPS 1761
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLS 2159
S S S P P P S P P P++ + P TP +PT
Sbjct: 1762 YSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPS-YSPTSPSYSPSSPRYTPQSPTYTP 1820
Query: 2160 PKGSIS 2165
S S
Sbjct: 1821 SSPSYS 1826
Score = 41.6 bits (96), Expect = 0.009
Identities = 45/195 (23%), Positives = 64/195 (32%), Gaps = 12/195 (6%)
Query: 1980 PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEG-----TSFPPQEPRH 2034
P + S + + PG P P +P+ S P + + S+ P P +
Sbjct: 1591 PSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSY 1650
Query: 2035 SP-QVKMAPTS---SPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQ 2090
SP +PTS SP P P + + P + S T
Sbjct: 1651 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1710
Query: 2091 PLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFP--PEI 2148
P SP + + S S S P P P S P P P++ + P P
Sbjct: 1711 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYT-PTSPSYSPTSPSY 1769
Query: 2149 TVTPPTPTLLSPKGS 2163
+ T P T SP S
Sbjct: 1770 SPTSPNYTPTSPNYS 1784
Score = 39.7 bits (91), Expect = 0.033
Identities = 43/193 (22%), Positives = 65/193 (33%), Gaps = 8/193 (4%)
Query: 1971 AAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTS---F 2027
+AA+ P S + PG P P P ++ P + E S +
Sbjct: 1549 SAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGY 1608
Query: 2028 PPQEPRHSP-QVKMAPTS---SPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQ 2083
PQ P +SP +PTS SP P+ P + + P
Sbjct: 1609 TPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1668
Query: 2084 EAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATK 2143
+ S T P SP + + S S S P P P S P P P++ +
Sbjct: 1669 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS-YSPTSPSY 1727
Query: 2144 FPPEITVTPPTPT 2156
P + +P +P+
Sbjct: 1728 SPTSPSYSPTSPS 1740
Score = 38.1 bits (87), Expect = 0.097
Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 9/127 (7%)
Query: 1924 TPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSA 1983
TPT+P + S E PT+P P P+ P + TT P S
Sbjct: 1840 TPTSPSYSPSSPE------YTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSP 1893
Query: 1984 SASTLDQSKDPGPPR--PHRPEATPSMASLGPEGEELARVA-EGTSFPPQEPRHSPQVKM 2040
+ S P P+ P P +P+ P + + +G+++ P P +SP
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPT 1953
Query: 2041 APTSSPA 2047
+SPA
Sbjct: 1954 YSLTSPA 1960
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 62.0 bits (149), Expect = 6e-09
Identities = 113/423 (26%), Positives = 150/423 (35%), Gaps = 61/423 (14%)
Query: 1775 RTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPL----------TPAQPAPAPAP 1824
R P LL RP P T +L L + PL T + AP P
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 1825 ATTTGTRAGGHPEE--PLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVE 1882
T+ A G E P S SG T R GQKG+
Sbjct: 80 TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT------RPGPLGQKGL-------- 125
Query: 1883 RIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVT 1942
RI +E + + EA A L A A+R SG TP TP P +R + T
Sbjct: 126 RISAEE-TVARGKATEAPKRSA-------LSAGARRDTSGPTPGTPS-PAMARRSRAAGT 176
Query: 1943 VVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRP 2002
V P P P+ + P++ PR ++++A+ T PS +A S G RP
Sbjct: 177 EV-GLPRPAPSARPRPPTEG---PRKSVSSASEHSTTEPSPAARR-RPSAGGGLQRP--- 228
Query: 2003 EATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWP----AEAAL 2058
A+ S++S AR P+ P H Q K + P P A AL
Sbjct: 229 -ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287
Query: 2059 G-TGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSS-GSAQPPEGHP 2116
G + P + P P A Q L SPP S+A +S GS H
Sbjct: 288 GPLSSSPLATPSPSAPPSP-------SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340
Query: 2117 GKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAI 2176
P P + PL P P+ A P + +PP LSP + S + L +
Sbjct: 341 FLPSPPLS---PLATPPPQAPPALALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 2177 LSA 2179
L A
Sbjct: 397 LQA 399
Score = 60.8 bits (146), Expect = 1e-08
Identities = 127/554 (22%), Positives = 183/554 (33%), Gaps = 98/554 (17%)
Query: 1670 GSERPGP-------KVCGLPGARMTTDVSHKAS-------PEDGQEGLPQPKKPPLADGS 1715
GS RP P +V G GA ++ +A PE P P A G
Sbjct: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGR 90
Query: 1716 G----------PGP--EPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP--RAGPTE-P 1760
G PGP PG G P+ Q G R E R TE P
Sbjct: 91 GERAPPAKNTSPGPVSSPGRASGTTRPGPLG--------QKGLRISAEETVARGKATEAP 142
Query: 1761 MDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAP 1820
++ + D P P PA R + TE+ L + SAR +P P +
Sbjct: 143 KRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 201
Query: 1821 A--------PAPATTTGTRAGGHPEEPLSRL--SRKRKLLEDTESGKTLLLDAYRVWQQG 1870
+ P+PA AGG + P SR S L SG +
Sbjct: 202 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS------------ 249
Query: 1871 QKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKH 1930
A R S+ Q + K LG + + +P+ P
Sbjct: 250 ----ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 1931 PKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTK-PRPALAAATTIITCPPSASASTLD 1989
P P + +P+ PS A T P L A + + PP + +T
Sbjct: 306 PS-----------APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 1990 QSKDPG---PP--RPHRPEATPSMASLG-PEGEELARVAEGTSFPPQEPRHSPQVKMA-- 2041
P PP P P A+P ++ L P + +A P P SP V+
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 2042 -PTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS 2100
P S P P P A + A P P A PL++PP +
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 2101 S---KAPSSGSAQPPEGHPGKPE--PSRAKSRPLPNMPKLVIPSAATKFPP-------EI 2148
+AP + + P + P P P +A P ++P + + + PP ++
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 2149 TVTPP-TPTLLSPK 2161
+PP +PTL +P+
Sbjct: 535 PPSPPASPTLQAPR 548
Score = 48.9 bits (115), Expect = 5e-05
Identities = 56/228 (24%), Positives = 77/228 (33%), Gaps = 25/228 (10%)
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEG-------EELARVAEGTSFPPQEPR 2033
P+A A L + PG PRP P ++ LG G E A G + P PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 2034 HSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLS 2093
P P +S PA+ G RP P + +A ET
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 2094 SPPTAASSKAPSSGSAQPPEG-HPGKPEPSRAK-----------SRPLPN---MPKLVIP 2138
A A S+G+ + G PG P P+ A+ RP P+ P P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 2139 SAATKFPPEITVTPPTPTLL---SPKGSISEETKQKLKSAILSAQSAA 2183
+ E + T P+P S G + + L S+ S A
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244
Score = 32.0 bits (71), Expect = 6.9
Identities = 45/164 (27%), Positives = 58/164 (35%), Gaps = 33/164 (20%)
Query: 1704 PQPKKPPLADGSGP--GPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPM 1761
P P PP S GP+ G P + DS + G A + P
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG---------AAASPPP 620
Query: 1762 DTSEATVCHS---DLERTPPL---------LPGRPARDRGPESRPTELSLEELSISARQQ 1809
D +E CH PPL LP PA GP S ++ E +
Sbjct: 621 D-AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYET-----EG 672
Query: 1810 PTPLTPAQPA--PAPAPATTTGTRAGGHPEEPLSRLSRKRKLLE 1851
P TPA A P P+P T+ G A G SR ++ +L E
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 716
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 62.0 bits (149), Expect = 6e-09
Identities = 98/435 (22%), Positives = 147/435 (33%), Gaps = 80/435 (18%)
Query: 1744 SGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELS 1803
S E ++S G D+ A+ E PP G+ E + + E S
Sbjct: 342 SDEEDGRDSDEEGAEGHRDSQSASG-----EERPPEADGKKGNSPNSEPPTPKTAWAETS 396
Query: 1804 ISARQQPTPLTPAQPAPAP--APATTTGTRA-----GGHPEEPLSRLSRKRKLLEDTESG 1856
+P P P P P P PA G GG P +P + ED +
Sbjct: 397 RPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP--------EDED-- 446
Query: 1857 KTLLLDAYRVWQQGQK------GVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQV 1910
W+Q +K +A + R R E M Q + AA + +K
Sbjct: 447 --------EAWRQRRKQSSSEISLAVERARRRREEEERRM---QEERRAACAEKLKRLDE 495
Query: 1911 HLGA-----AAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSD---A 1962
GA A+ A P+TP P + P A P P + P+ A
Sbjct: 496 KFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPA 555
Query: 1963 HTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVA 2022
+ P P +AAA T+++ S S ST S + P P P + GPE
Sbjct: 556 QSTPTPGVAAAPTLVSGGGSTS-STSSGSFEASPVEPQLP------SKEGPE-------- 600
Query: 2023 EGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEA 2082
PP+E + P ++P P P +G +P +G P+ ++
Sbjct: 601 -----PPEE--------VPPPTTPPVPKVEPKGDGIGPTRQP--PSQGLGYPKYQKSLPP 645
Query: 2083 QEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAAT 2142
+ + + L + GSA P P P+P + P P P P
Sbjct: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPP---PPPKA 702
Query: 2143 KFPPEITVTPPTPTL 2157
+P + PP P +
Sbjct: 703 LYPGALGRPPPMPPM 717
Score = 48.5 bits (114), Expect = 7e-05
Identities = 109/474 (22%), Positives = 144/474 (30%), Gaps = 68/474 (14%)
Query: 1672 ERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGP--GPEPGGKVGLLN 1729
E PGP+ P S E + P PKK P + + GPE G K
Sbjct: 857 EEPGPRPLPWP----------PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR-- 904
Query: 1730 HRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRG 1789
+ +G R+ + R GP S PP PG P R G
Sbjct: 905 ----GVGSGGQGPPPPRRESRTETRWGPRPG----------SSRRGIPPEEPGAPPRRAG 950
Query: 1790 P-ESRPTELSLEELSISARQQPTPLTPAQPAPAPA---PATTTGTRAGGHPEEP----LS 1841
P + P +EEL P PL P P P T + GG E P LS
Sbjct: 951 PIKKPPPPTKVEEL------PPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS 1004
Query: 1842 RLSRKRKLLEDTESGKTLL----LDAYRVWQQGQKGVAYDLGRVERIMS-ETYMLIKQVD 1896
R R+ G T Y +G +G GR R +Y + D
Sbjct: 1005 PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDD 1064
Query: 1897 EEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSV 1956
G A S + + PK R+ D P+D
Sbjct: 1065 GRGGGTGGPNHPPAPRGRTASETRS-EGSEYEEIPKRRRQRGSETGSETHESDLAPSDK- 1122
Query: 1957 QRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGE 2016
+ P+ P+ + PP A S R P PS G G
Sbjct: 1123 EAPT-----PKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRG-GGR 1176
Query: 2017 ELARVAEGTSFPPQE--PRHSPQVKMAPTSSPAEPHCWPAE----AALGTGAEPTCSQEG 2070
+V G S P + P+ P + P+ P + P A G+ E
Sbjct: 1177 PPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMED 1236
Query: 2071 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRA 2124
RP RR G AQ+ PP K +A+ EG P P+ A
Sbjct: 1237 GERPRRRRHGRAQQQ-------DKPPRFRRLKQERENAARGSEGKPSLTLPASA 1283
Score = 42.4 bits (98), Expect = 0.005
Identities = 41/157 (26%), Positives = 57/157 (36%), Gaps = 18/157 (11%)
Query: 2016 EELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPE 2075
E+L R+ E P + + P A S+PA P P E P + + P
Sbjct: 488 EKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEP- 546
Query: 2076 PRRDGEAQEAASETQPLSSPPTAASSKAPS--SGSAQPPEGHPGKPEPSRAKSRPLPNMP 2133
E ++ P S PT + AP+ SG G E S + P +P
Sbjct: 547 --------EEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE----PQLP 594
Query: 2134 KLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQ 2170
P + PP TPP P + PKG T+Q
Sbjct: 595 SKEGPEPPEEVPP--PTTPPVPK-VEPKGDGIGPTRQ 628
Score = 42.0 bits (97), Expect = 0.007
Identities = 131/542 (24%), Positives = 172/542 (31%), Gaps = 131/542 (24%)
Query: 1708 KPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP---RAGPTEPMDTS 1764
+PPL D PG P G V + DS S E D+ +P R T P+D
Sbjct: 738 RPPL-DFYPPGVHPSGLV--------PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPK 788
Query: 1765 EATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAP 1824
A V + PA R P + P + +E R + TP P P P
Sbjct: 789 LAWV--------GDVFTATPAEPR-PLTSPLRQAADEDDKGMRSE----TPPVPPPPPYL 835
Query: 1825 ATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVA---YDLGRV 1881
A+ G G P P+SR + E G L W G VA +
Sbjct: 836 ASYPGFPENGAPGPPISRFPLE-------EPGPRPL-----PWPPGSDEVAKIQTPPPKK 883
Query: 1882 ERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPV 1941
E ET L EA + A G R+ S P SR P
Sbjct: 884 EPPKEETAQL---TGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPE 940
Query: 1942 TVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKD-PGPPRPH 2000
P AP P A +++P P P T + PP L+Q + P PP+P
Sbjct: 941 E--PGAP-PRRAGPIKKP------PPP-----TKVEELPP----KPLEQGDETPKPPKPD 982
Query: 2001 ----------RPEATPSMASLGP----------------------EGEELA--------- 2019
P+ TP +L P GE A
Sbjct: 983 PLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTY 1042
Query: 2020 ----RVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPE 2075
R A F + T P P A G A T S+ +
Sbjct: 1043 GGRGRGARSREFRSYREFRGDDGRGGGTGGPNHP-----PAPRGRTASETRSEGSEYEEI 1097
Query: 2076 P-RRDGEAQEAASETQPLSSPPTAASSKAPSSGS------AQPPEGHPGKPEPSRAKSRP 2128
P RR E SET P+ + P G+ A PP G P P P+R +R
Sbjct: 1098 PKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARG 1157
Query: 2129 LPNMPKLVIPS----AATKFPPEITV--TPPTPTLL---SPKGSI---SEETKQKLKSAI 2176
+PS + PP++ +PP +L P G + E K+KL
Sbjct: 1158 GRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGP 1217
Query: 2177 LS 2178
LS
Sbjct: 1218 LS 1219
Score = 40.8 bits (94), Expect = 0.015
Identities = 100/484 (20%), Positives = 145/484 (29%), Gaps = 102/484 (21%)
Query: 1691 SHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDK 1750
S ++SP+ G +G + GP PGG LN P G
Sbjct: 1667 SQRSSPDGGLKGAAE----------GPPKRPGGS-SPLNAVPCEGPPGS----------- 1704
Query: 1751 ESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQP 1810
E PR P P D +L R PL PG +R + +
Sbjct: 1705 EPPRRPPPAPHDGDR-----KELPREQPLPPGPIGTERSQRT---------------DRG 1744
Query: 1811 TPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQG 1870
T P +P+ P P GT + + K ++ + T + R W+
Sbjct: 1745 TEPGPIRPSHRPGPPVQFGT--SDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELL 1802
Query: 1871 QKGVA--------YDLGR-VERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
A D G V S L +V +A + + + + +
Sbjct: 1803 PSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSG 1862
Query: 1922 GDTPTTPK-HPKDSRENFFPVTVVPTAPDPVPADSV----------------------QR 1958
G P TP HP S+ + P P P P ++ +
Sbjct: 1863 GFRPGTPSLHPYRSQPLYLP-------PGPAPPSALLSGLALKGQFLDFSTMQATELGKL 1915
Query: 1959 PSDAHTKPRPALAAATTIITCP-PSASASTLDQSKD-------------PGPPRPHRPEA 2004
P+ P P+ + CP P S L +D PG P
Sbjct: 1916 PAGGVLYPPPSFLYSPAF--CPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSG 1973
Query: 2005 TPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEP 2064
P+ L P + V S PP P P + + P +P P+ A A
Sbjct: 1974 APAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQP---PSLAVRPPPAPA 2030
Query: 2065 TCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRA 2124
T RP P G A+ E +P +S+ S PP G SR
Sbjct: 2031 TRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRL 2090
Query: 2125 KSRP 2128
K+ P
Sbjct: 2091 KATP 2094
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 61.6 bits (148), Expect = 8e-09
Identities = 75/262 (28%), Positives = 107/262 (40%), Gaps = 49/262 (18%)
Query: 1923 DTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPS 1982
++PT+P P ++ P +P +P P + ++ P P + + P S
Sbjct: 455 ESPTSP--PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE---ESPLSPPPES 509
Query: 1983 ASASTLDQSK----DPGPPRPHR-------PEATP-----SMASLGPEGEELARVAEGTS 2026
+ S L++S + PP P PEA+P + L P EEL TS
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP-----TS 564
Query: 2027 FPPQEPRHSPQVKMAPTSSPAE--PHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQE 2084
PP+ R SP + +P S P E P P EA+ +E L P P
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP----FEESPLSPPP-------- 612
Query: 2085 AASETQPLSSPPTAASSKAPSSGS--AQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAAT 2142
E PLS PP A+ P S + PPE P P P ++ PLP + +L P +
Sbjct: 613 ---EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 2143 KF--PPEITVT--PPTPTLLSP 2160
PPE + T PP + LSP
Sbjct: 670 PLSPPPEESPTSPPPEASRLSP 691
Score = 61.2 bits (147), Expect = 1e-08
Identities = 113/477 (23%), Positives = 155/477 (32%), Gaps = 89/477 (18%)
Query: 1696 PEDGQEGLPQPKKPPLADGSGPGP-EPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPR 1754
P + P P+ P++ P P +V L+ PV + ESP
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE--------ESPL 671
Query: 1755 AGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLT 1814
+ P E TS S L P P P + P S P E SL L + + +PL
Sbjct: 672 SPPPEESPTSPPPEA-SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL----EESPLL 726
Query: 1815 PAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGV 1874
P P P + G PEEP LS +
Sbjct: 727 PLPEEPQLCPRSE-GPHLSPRPEEP--HLSPR---------------------------- 755
Query: 1875 AYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDS 1934
E L Q +E Q + C + + P P++
Sbjct: 756 -----------PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 1935 RENFFPVTVVPTAPDPVPADSV--QRPSDAHTKPRPALAAATTIITCPPSASASTLDQSK 1992
+ P T P PVP + +P ++H P+ + ++ P S + + K
Sbjct: 805 --HLSPQTEEPHL-SPVPEEPCLSPQPEESHLSPQ----SEEPCLSPRPEESHLSPELEK 857
Query: 1993 DPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHC- 2051
P PRP +P P P EEL PP EP SP + S P EP
Sbjct: 858 PPLSPRPEKPPEEPGQC---PAPEELPLFP-----PPGEPSLSPLLGEPALSEPGEPPLS 909
Query: 2052 -WPAEAALGTGAEPTCSQEGKLRPEPRRD-------GEAQEAASETQPLSSPPTAASSKA 2103
P E L EP+ S + + P+P A A S L P A
Sbjct: 910 PLPEELPLSPSGEPSLSPQ-LMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSD 968
Query: 2104 PSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
P S A P P P P + P P P ++ PS P V P +P L+ P
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPS------PGSPVGPASPILMEP 1019
Score = 58.5 bits (140), Expect = 7e-08
Identities = 121/540 (22%), Positives = 189/540 (35%), Gaps = 68/540 (12%)
Query: 1672 ERPGPKVCG---LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGP-EPGGKVGL 1727
+ PGP C L A + + +A + LP P++ PL+ P P +
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASR 466
Query: 1728 LNHRPVAMDAGDSADQSG-ERKDKESPRAGPTE--PMDTSEATVCHSDLERTP----PLL 1780
L+ P + A + R +ESP + P E P+ + S LE +P
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 1781 PGRPARDRG----PESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHP 1836
P PA + PE+ P EE +S + P +P A +P +
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 1837 EEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVD 1896
E P+S +L E ++ + R+ ++ M
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPP-----EESPLSPPPEASRLSPPPEDSPM--SPPP 639
Query: 1897 EEAALEQAVKFCQVHLGAAAQRQASG--DTPTTPKHPKDSRENFFPVTVVPTAPDPVPAD 1954
EE+ + + ++ R + ++P +P P++S PT+P P +
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP-PEES----------PTSPPPEASR 688
Query: 1955 SVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSM----AS 2010
P D+ T P P + A+ PP S +L + P P P P+ P S
Sbjct: 689 LSPPPEDSPTSPPPEDSPASP----PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
Query: 2011 LGPEGEELARVAEGTSFPPQ--EPRHSPQ-VKMAPTSSPAEPHCWPAEAALGTGAEP--- 2064
PE L+ E PQ EP SPQ + + P EPH P +P
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 2065 ------------TCSQEGKLRPEPRR---DGEAQEAASETQPLSSPPTAASSKAPSSGSA 2109
+E L P+P +++E +P S + K P S
Sbjct: 805 HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864
Query: 2110 QPPEGHPGK-PEPSRAKSRPLPNMPKL--VIPSAATKFPPEITVTP-PTPTLLSPKGSIS 2165
+ P PG+ P P P P P L ++ A P E ++P P LSP G S
Sbjct: 865 EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924
Score = 45.1 bits (105), Expect = 8e-04
Identities = 57/215 (26%), Positives = 74/215 (34%), Gaps = 19/215 (8%)
Query: 1955 SVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPE 2014
S P D T AL A P T Q K+PGP + + L P+
Sbjct: 373 SPPEPGDTPTDEPDALYVACQ---GQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQ 429
Query: 2015 GEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEP-HCWPAEAALGTGAEPTCS------ 2067
E PP+E SP + +PTS P E P L P
Sbjct: 430 LEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPL 489
Query: 2068 QEGKLRPEPRRDGEAQEAAS------ETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEP 2121
+E L P P + S E PLS P + S A + + PPE P P
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 2122 SRAKSRPLP-NMPKLVIPSAATKFPP--EITVTPP 2153
+ P P +P P A+ PP E ++PP
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Score = 40.0 bits (92), Expect = 0.026
Identities = 120/508 (23%), Positives = 157/508 (30%), Gaps = 88/508 (17%)
Query: 1673 RPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRP 1732
+PG P A T + +P KPP GS PGP+ G++ L P
Sbjct: 2109 QPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPA--GSVPGPDSPGEL-FLKLPP 2165
Query: 1733 VAMDAGDSADQSGERK----DKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDR 1788
S D G + P A PT P S + PP+L A R
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-----TGAPAQPPMLG---ASSR 2217
Query: 1789 GPESRPTELSLEELSISARQQPTP---LTPAQPAPAPAPATTTGTRAGGHPEEPLSR--- 1842
+P E Q TP L P P+ + GG EPL
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Query: 1843 LSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAY---DLGRVERIMSETYM--LIKQVDE 1897
RK LE + + G +Y +LG V+ S T++ L + +
Sbjct: 2278 FGESRKALEVKKE------------ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPD 2325
Query: 1898 EAALEQAVKFCQVH-----LGAAAQRQ--ASGDTPTTPKHPKDSRENFF--PVTVVPTAP 1948
+ QV LG Q A P+ P HP R + P P P
Sbjct: 2326 VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP 2385
Query: 1949 DPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEA---- 2004
P P S PR + + + P + +S S+ P PRP EA
Sbjct: 2386 RPQPPPP---ESCCALPPRSLPSDPFSRVPASPQSQSS----SQSPLTPRPLSAEAFCPS 2438
Query: 2005 --TPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGA 2062
TP S P +R F P PQ + + H +LG G
Sbjct: 2439 PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH-----TSLGAGG 2493
Query: 2063 EPTCSQEGKLRPEPRRDGEAQEAASETQP---LSSPPTAASSKAPS-----------SGS 2108
P G GE QP + SP T A PS S
Sbjct: 2494 FPAALPAGPA-------GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPS 2546
Query: 2109 AQPPEGHPGKPEPSRAKSR--PLPNMPK 2134
+PP PG P P S P P + K
Sbjct: 2547 LKPPVPQPGLPPPHGINSHFGPGPTLGK 2574
Score = 37.4 bits (85), Expect = 0.17
Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 10/102 (9%)
Query: 2071 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGH-PGKPEPSRAKSRPL 2129
++ P+P G AA+ T + SP T A + G +PP G PG P +
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 2130 PNMPKLVIPS-----AATKFP--PEITVTPPT-PTLLSPKGS 2163
P +P V PS A +P P PPT P SP G+
Sbjct: 2165 PQVPAQV-PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA 2205
Score = 37.4 bits (85), Expect = 0.17
Identities = 60/274 (21%), Positives = 95/274 (34%), Gaps = 27/274 (9%)
Query: 1945 PTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEA 2004
P P P P+ S Q P P P+ + T PP+ PG P+P P
Sbjct: 4304 PVHPTPPPS-SPQEPKRPSQLPSPS-SQLPTEAQLPPT----------HPGTPKPQGPTL 4351
Query: 2005 TPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEP 2064
P + P +LA P +P + +A T P + P G
Sbjct: 4352 EPPPGRVSPAAAQLADTLFSKGLGPWDPPDN----LAETQKPEQSSLVPGHLDQVNGQVV 4407
Query: 2065 TCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQP--PEGHPGKPEPS 2122
+ + ++ EPR + A A S + + P A + A P GH +
Sbjct: 4408 PEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLL 4467
Query: 2123 RAK---------SRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLK 2173
RAK S L I S ++ TP + + ++ + K+ K
Sbjct: 4468 RAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQK 4527
Query: 2174 SAILSAQSAANVRKESLCQPALEVLETSSQESSL 2207
++ S +RKE + + +L+ QE SL
Sbjct: 4528 ASDRLVSSRKKLRKEDGVRASEALLKQLKQELSL 4561
Score = 36.6 bits (83), Expect = 0.28
Identities = 54/214 (25%), Positives = 74/214 (34%), Gaps = 46/214 (21%)
Query: 1993 DPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCW 2052
+PG P+A P+G + TS P+EP P A+P
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHV------TSMQPKEP--------GPLQCEAKP-LG 420
Query: 2053 PAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPP 2112
A L E ++E L P P E PLS PP S ++ PP
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPP-----------EESPLSPPPE-------ESPTSPPP 462
Query: 2113 EGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKL 2172
E P P + PLP L P + P PP + LSP S + +
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSP-----PPEESPLSPPPESSPFSPLE- 516
Query: 2173 KSAILSAQSAANVRKESLCQPALEVLETSSQESS 2206
+S + +ES PALE + E+S
Sbjct: 517 -------ESPLSPPEESPPSPALETPLSPPPEAS 543
Score = 35.8 bits (81), Expect = 0.48
Identities = 55/237 (23%), Positives = 91/237 (38%), Gaps = 26/237 (10%)
Query: 1988 LDQSKDPGPPRP----HRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPT 2043
+ + P PP+P + P + + G+ A++ + PQ SPQ +
Sbjct: 4164 MQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223
Query: 2044 SSPAEPHCWPAEAALGTGA--EP---TCSQEGKLRPEPR-------RDGEAQEAASETQP 2091
+ + ++A T EP T +G L +P+ + G QE + +P
Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP 4283
Query: 2092 LSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVT 2151
P A A S+G P HP P PS + P+ +PS +++ P E +
Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPV-HP-TPPPSSPQEPKRPSQ----LPSPSSQLPTEAQLP 4337
Query: 2152 PPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESL--CQPALEVLETSSQESS 2206
P P P+G E ++ A +AQ A + + L P + ET E S
Sbjct: 4338 PTHPGTPKPQGPTLEPPPGRVSPA--AAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
Score = 34.7 bits (78), Expect = 1.1
Identities = 41/172 (23%), Positives = 61/172 (35%), Gaps = 21/172 (12%)
Query: 1976 IITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHS 2035
+ P + AS ++ RP P ++A P ++ R T +P
Sbjct: 2326 VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYT-----DPYAQ 2380
Query: 2036 PQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSP 2095
P + P P E C AL + P+ P R Q +S PL+
Sbjct: 2381 PPLTPRPQPPPPESCC-----ALPPRSLPS-------DPFSRVPASPQSQSSSQSPLTPR 2428
Query: 2096 PTAASSKAPSSGSAQPPEGHPGKPEPSRAKSR----PLPNMPKLVIPSAATK 2143
P +A + PS + + P PSR +SR PL P+ P A K
Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFK 2480
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 61.2 bits (147), Expect = 1e-08
Identities = 127/563 (22%), Positives = 197/563 (34%), Gaps = 95/563 (16%)
Query: 1696 PEDGQEGLPQPKKPPLADGSGPGPEPGGKV-------GLLNHR--PVAMDAGDSADQSGE 1746
P G LP P P+ GS G G V GLLN + P + A +
Sbjct: 969 PGVGAGDLPGPTSAPVPSGSQSGGR-GSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVS 1027
Query: 1747 RKDKESPRAG-----PTEPMDTSEATVCHSDLERTPP-----LLPG-----RPARDRGPE 1791
R D+ESP A P P + S PP LLP R R G +
Sbjct: 1028 RGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQ 1087
Query: 1792 SRPTELSLEELSI-----------SARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPL 1840
P EL S+R P P T A P P P+ +T +P
Sbjct: 1088 EAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTP-----KPT 1142
Query: 1841 SRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAA 1900
S+ +R R ++ + ++ A + Q + D + + SE QV
Sbjct: 1143 SQATRSRTNRSSVKTPEPVVPTAPEL----QPSTSTD----QPVTSEP---TSQVTRGRK 1191
Query: 1901 LEQAVKFCQVHLGAAAQRQ--ASGDTPTTPKHPKDS---RENFF----PVTVVPTAPDPV 1951
+VK + + A + Q S D P T + + R+N P VVPTAP+
Sbjct: 1192 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQ 1251
Query: 1952 PADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASL 2011
P+ S +P T+ T + K P P P PE PS ++
Sbjct: 1252 PSTSTDQP-------------VTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD 1298
Query: 2012 GPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGK 2071
P + TS + + VK T P P E + T + +
Sbjct: 1299 RPV------TPKPTSRTTRSRTNMSSVKTPETVVPTAP-----ELQISTSTDQPVTP--- 1344
Query: 2072 LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPN 2131
+P R +S P S+ P A PS+ + QP P K+R
Sbjct: 1345 -KPTSRTTRSRTNMSSVKNPESTVPIAPELP-PSTSTEQPVTPEPTSRATRGRKNRSSGK 1402
Query: 2132 MPKLVIPSAATKFPPEITVTP--PTPTLLSPKGSISEETKQKLKSAILSA---QSAANVR 2186
P+ ++P+A P T P P PT + +G + + + ++ + +A Q + +
Sbjct: 1403 TPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTD 1462
Query: 2187 KESLCQPALEVLETSSQESSLES 2209
+ +P + + SS+++
Sbjct: 1463 QPVTPEPTSQATRGRTDRSSVKT 1485
Score = 60.1 bits (144), Expect = 2e-08
Identities = 103/494 (20%), Positives = 169/494 (34%), Gaps = 54/494 (10%)
Query: 1743 QSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEEL 1802
Q G ++ E+P + EP TP PA PE P+ + + +
Sbjct: 1083 QDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTP-----FPATSAAPEPHPSTSTAQPV 1137
Query: 1803 SISARQQ-------------PTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKL 1849
+ Q P P+ P P P+ +T + EP S+++R RK
Sbjct: 1138 TPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-----EPTSQVTRGRKS 1192
Query: 1850 LEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQ 1909
++ +T++ A + Q + D S+ K E V
Sbjct: 1193 RSSVKTPETVVPTALEL----QPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAP 1248
Query: 1910 VHLGAAAQRQASGDTPT--TPKHPKDSRENFFPVTVVPTAPDPVPADSVQRP-----SDA 1962
+ + Q PT + K+ P VVPTAP+ P+ S RP +
Sbjct: 1249 ELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSR 1308
Query: 1963 HTKPRPALAAATTIITCPPSASASTLDQSKD-PGPPRPHRPEATPSMASLGPEGEELARV 2021
T+ R +++ T T P+A + S D P P+P T S ++ + V
Sbjct: 1309 TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP-TSRTTRSRTNMSSVKNPESTV 1367
Query: 2022 AEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGE 2081
PP P V PTS + G E KL P D
Sbjct: 1368 PIAPELPPSTSTEQP-VTPEPTSRATRGR---KNRSSGKTPETLVPTAPKLEPSTSTD-- 1421
Query: 2082 AQEAASETQPLSSPPTAASSKAPSSGSA--QPPEGHPGKPEPSRAKSRPLPNMPKLVIPS 2139
QP++ PT+ +++ ++ S+ P P PE + S P P+ +
Sbjct: 1422 --------QPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQA 1473
Query: 2140 AATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLE 2199
+ TP T +P+ S T Q + S S + + S+ P E +
Sbjct: 1474 TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTP--ETVV 1531
Query: 2200 TSSQESSLESETDE 2213
++ E + TD+
Sbjct: 1532 PAAPELQPSTSTDQ 1545
Score = 56.6 bits (135), Expect = 3e-07
Identities = 108/468 (23%), Positives = 176/468 (37%), Gaps = 75/468 (16%)
Query: 1755 AGPTEPMDTSEAT---VCHSDLERTPPLLPGRP------ARDRGPESRPT-ELSLEELSI 1804
A P P TS+AT S ++ P++P P + D+ S PT +++ S
Sbjct: 1134 AQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSR 1193
Query: 1805 SARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAY 1864
S+ + P + P P+ +T + EP S+ +R RK ++ + ++ A
Sbjct: 1194 SSVKTPETVVPTALELQPSTSTDRPVTS-----EPTSQATRGRKNRSSVKTPEPVVPTAP 1248
Query: 1865 RVWQQGQKGVAYDLGRVERIMSE-TYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGD 1923
+ Q + D + + SE TY + ++++ V + S D
Sbjct: 1249 EL----QPSTSTD----QPVTSEPTYQATRGRKNRSSVKTPEPV--VPTAPELRPSTSTD 1298
Query: 1924 TPTTPK---HPKDSRENFF----PVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTI 1976
P TPK SR N P TVVPTAP+ + S +P P+P
Sbjct: 1299 RPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQP----VTPKP-------- 1346
Query: 1977 ITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGP-EGEELARVAEGT---------- 2025
T + S + + K+P P PE PS ++ P E +R G
Sbjct: 1347 -TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPE 1405
Query: 2026 SFPPQEPRHSPQ------VKMAPTSSPAEPHCWPA-----EAALGTGAE--PTCSQEGKL 2072
+ P P+ P V PTS + E + T E P+ S + +
Sbjct: 1406 TLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPV 1465
Query: 2073 RPEPRRDGEA--QEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP 2130
PEP + +S P + PTA +A S+ + QP P K+R
Sbjct: 1466 TPEPTSQATRGRTDRSSVKTPETVVPTAPELQA-SASTDQPVTSEPTSRTTRGRKNRSSV 1524
Query: 2131 NMPKLVIPSAATKFPPEITVTP--PTPTLLSPKGSISEETKQKLKSAI 2176
P+ V+P+A P T P P PT + +G + + + +S +
Sbjct: 1525 KTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIV 1572
Score = 43.9 bits (102), Expect = 0.002
Identities = 103/522 (19%), Positives = 180/522 (34%), Gaps = 64/522 (12%)
Query: 1654 ILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLP-QPKKPPLA 1712
+ T + + T EL + P V P +R T ++ +S ++ + +P P+ PP
Sbjct: 1319 VKTPETVVPTAPELQISTSTDQP-VTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1377
Query: 1713 DGSGP-GPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEAT---V 1768
P PEP + + ++ + + + + P P TS+AT
Sbjct: 1378 STEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRT 1437
Query: 1769 CHSDLERTPPLLPGRPARDRG----------PESRPTELSLEELSISARQQPTPLTPAQP 1818
S ++ ++P P P S+ T + S+ + P P
Sbjct: 1438 NRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQ 1497
Query: 1819 APAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDL 1878
A A T EP SR +R RK ++ +T++ A + Q + D
Sbjct: 1498 ASASTDQPVTS--------EPTSRTTRGRKNRSSVKTPETVVPAAPEL----QPSTSTDQ 1545
Query: 1879 GRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTT-PKHPKDSREN 1937
S E V + ++ Q PT+ + +R +
Sbjct: 1546 PVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSS 1605
Query: 1938 F-FPVTVVPTAPDPVPADSVQRP-----SDAHTKPRPALAAATTIITCPPSASASTLDQS 1991
P VVPTAP+P P S +P + T+ + ++ T P+AS
Sbjct: 1606 VKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAAS------- 1658
Query: 1992 KDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHC 2051
D P P TP + G + + L P P V T P P
Sbjct: 1659 -DLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPV---TTDQPISPE- 1713
Query: 2052 WPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSP--PTAASSKAPSSGSA 2109
+P+C + + P + A + +P S+P P + +S+ G+
Sbjct: 1714 --------PITQPSCIKRQRAAGNP----GSLAAPIDHKPCSAPLEPKSQASRNQRWGAV 1761
Query: 2110 QPPEGHPGKPEPSRAKSRPLP---NMPKLVIPSAATKFPPEI 2148
+ E PEP+ + P + + V P+ ++F PE+
Sbjct: 1762 RAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPEL 1803
Score = 40.8 bits (94), Expect = 0.015
Identities = 97/455 (21%), Positives = 157/455 (34%), Gaps = 69/455 (15%)
Query: 1757 PTEPMDTSEATVCHSDL------ERTPPLLPGRP---ARDRGPESRPTELSLE-ELSISA 1806
P P TS T +++ E T P+ P P + ++ PT + + S+
Sbjct: 1341 PVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Query: 1807 RQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRV 1866
+ P L P P P+ +T EP S+ +R R ++ +T++ A +
Sbjct: 1401 GKTPETLVPTAPKLEPSTSTDQPVTP-----EPTSQATRGRTNRSSVKTPETVVPTAPEL 1455
Query: 1867 WQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDT-- 1924
Q + D T Q +VK + + A + QAS T
Sbjct: 1456 ----QPSTSTD-------QPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQ 1504
Query: 1925 -----PT--TPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTII 1977
PT T + K+ P TVVP AP+ P+ S +P P P
Sbjct: 1505 PVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP----VTPEP--------- 1551
Query: 1978 TCPPSASASTLDQSKDPGPPRPHRPEATPSMAS---LGPEGEELARVAEGTSFPPQEPRH 2034
T + + K P P PE PS + + PE A + P
Sbjct: 1552 TSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTP-- 1609
Query: 2035 SPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLR-PEPRRDGEAQEAASETQPLS 2093
P V AP P P L + A + ++ P+P + AAS+ +P +
Sbjct: 1610 EPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP-----VEPAASDLEPFT 1664
Query: 2094 SPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPP 2153
+ + +A + G G S ++ P+P P+ P + +T P
Sbjct: 1665 PTDQSVTPEAIAQG------GQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQP 1718
Query: 2154 T----PTLLSPKGSISEETKQKLKSAILSAQSAAN 2184
+ GS++ K SA L +S A+
Sbjct: 1719 SCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQAS 1753
Score = 32.3 bits (72), Expect = 5.3
Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 37/195 (18%)
Query: 1292 KEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSPPYT 1351
+EA E P + E PK + + S+ P P S P TS
Sbjct: 1087 QEAPEAPLSSELEPFHPKPKIRTR---------KSSRMTPFPATSAAPEPHPS-TSTAQP 1136
Query: 1352 ATPIDHDYVKCKKPHQQATPDDRSQDS---------TAVALSDSSST-QDFFNEPTSLLE 1401
TP KP QAT ++ S TA L S+ST Q +EPTS +
Sbjct: 1137 VTP---------KPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVT 1187
Query: 1402 GSRKSYTEKRLPILSSQAGATGKDLQ--GATEERGKNEESLESTEGFRAAEQGVQKPAAE 1459
RKS + + P T +LQ +T+ +E + ++T G R V+ P
Sbjct: 1188 RGRKSRSSVKTP---ETVVPTALELQPSTSTDRPVTSEPTSQATRG-RKNRSSVKTPEPV 1243
Query: 1460 TPASACIPGKPSAST 1474
P + + +PS ST
Sbjct: 1244 VPTAPEL--QPSTST 1256
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 58.9 bits (141), Expect = 5e-08
Identities = 128/584 (21%), Positives = 201/584 (34%), Gaps = 89/584 (15%)
Query: 1694 ASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESP 1753
A P + + P + + + P E G + L N A + ++ +K +P
Sbjct: 496 AEPTENGQRTPFANEKTTSSSAEP-TEHGERTPLANENTTPSPAEPTENRERTANEKTTP 554
Query: 1754 RAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGP---------ESRPTELSLEELSI 1804
P EP + + T ++ + TP L R P + PTE EE +
Sbjct: 555 --SPAEPTENGDRTPLANE-KTTPSLAEPTENGQRTPFANEKTTSSSAEPTEH--EERTP 609
Query: 1805 SARQQPTPLTPAQPA------------PAPAPAT-----TTGTRAGGHPEEPLSRLSRKR 1847
A + TP +PA+P P+PA T T + P EP +R+R
Sbjct: 610 LANENTTP-SPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTE--NRER 666
Query: 1848 KLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKF 1907
E T S + GQ+ + E+ S + + + +
Sbjct: 667 TANEKTTSSPA------EPTENGQRTPFAN----EKTTSSSAEPTEHGERTPLANENTTL 716
Query: 1908 CQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPV-PADSVQRPSDAHTKP 1966
+R A+ T P P ++RE T P P P ++ R A+ K
Sbjct: 717 SPAEPTENRERTANEKTTPFPAEPTENRER---TANENTTPSPAQPTENGDRTPLANEKT 773
Query: 1967 RPALAAATTIITCPPSASASTLDQSKDPGPPRPHRP---EATPSMASLGPEGEELARVAE 2023
P+LA T P A+ T S +P P E T S + E E +
Sbjct: 774 TPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEK 833
Query: 2024 GTSFP--PQEPRHSPQVKMAPTSSPAEP---HCW---------PAEAALGTGAEPTCSQE 2069
T FP P E R S + T PAEP W PAE P +++
Sbjct: 834 TTQFPAEPTENRESTANEKT-TPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEK 892
Query: 2070 GKLRP-EPRRDGEAQEAASE-TQPLSSPPTAASSKAPSSGS------AQPPE------GH 2115
L P EP +GE +E T P S+ PT + P + A+P E
Sbjct: 893 TTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANE 952
Query: 2116 PGKPEPSRAKSRPLPNMPKLVIPSAA--------TKFPPEITVTPPTPTLLSPKGSISEE 2167
P P++ + + PS+A T E T T PT + + + +E+
Sbjct: 953 KATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEK 1012
Query: 2168 TKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESET 2211
T + + ++++ PA S+ E+ T
Sbjct: 1013 TTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTT 1056
Score = 42.7 bits (99), Expect = 0.004
Identities = 66/302 (21%), Positives = 104/302 (34%), Gaps = 38/302 (12%)
Query: 1917 QRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTI 1976
+R A+ +T +P P + E P+ +P + +R A+ K + A +T
Sbjct: 366 ERTANENTTPSPAEPTEHGERTANENTTPSPAEPT--EHGERTPFANDKTTSSSAESTEH 423
Query: 1977 ITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSP 2036
P A+ +T +P R + + GP E T+ P EP +
Sbjct: 424 GERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENR 483
Query: 2037 Q--VKMAPTSSPAEP------HCWPAEAALGTGAEPTCSQE------GKLRPEPRRDGEA 2082
+ T SPAEP + E + AEPT E P P E
Sbjct: 484 ETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTEN 543
Query: 2083 QE--AASETQPLSSPPTAASSKAPSSGS------AQPPEGHPGKP-----------EPSR 2123
+E A +T P + PT + P + A+P E P EP+
Sbjct: 544 RERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTE 603
Query: 2124 AKSR-PLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSA 2182
+ R PL N P+ T+ TP+ P + + E K+ + A+
Sbjct: 604 HEERTPLANENTTPSPAEPTENRERTANENTTPSPAGP--TENREMTANEKTTLFPAEPT 661
Query: 2183 AN 2184
N
Sbjct: 662 EN 663
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 58.2 bits (139), Expect = 9e-08
Identities = 112/509 (22%), Positives = 167/509 (32%), Gaps = 86/509 (16%)
Query: 1667 LAEGSER--PGPKVCGLPGARMTTDVSHKASPE----DGQEGLPQPKKPPLADGSGPGPE 1720
L+EG R GP++ + G + A P G E P+ + G P P
Sbjct: 550 LSEGGRRLAKGPELMAIEGLE-NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPL 608
Query: 1721 PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLL 1780
P + P G + SG +++ +P+ +P E + ER P L
Sbjct: 609 PPAR------SPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGT-ERPPKLC 661
Query: 1781 PGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAP-ATTTGTRAGGHPEEP 1839
P + GP P + S P+ PAP P P A + G P P
Sbjct: 662 SSLPGQ--GPP--PYVFMYPQGS-----------PSSPAPGPPPGAPWAFSYLAGPPATP 706
Query: 1840 LSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEA 1899
KR+ + G T + +G A G V + L ++ A
Sbjct: 707 PDPPRPKRRSHSLSRPGPT---------EGDAEGEAE--GPVGSTLGSYATLTRRPGRSA 755
Query: 1900 ALEQAVKFCQVHLGAAAQRQA-------SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVP 1952
+ + + Q+ G P PK +V +P+P P
Sbjct: 756 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLS---------SVSGPSPEPPP 806
Query: 1953 ADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLG 2012
D P + T PR + S+ PGPP P P + G
Sbjct: 807 LDESPGPKEGATGPRRRTLSEPA-------------GPSEPPGPPAPAGPASDTEEEEPG 853
Query: 2013 PEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKL 2072
PEG +R + G P E + +K P PA P P E + G + ++ +
Sbjct: 854 PEGTPPSRGSSGEGLPFAE-EGNLTIKQRP--KPAGPP--PRETPVPPGLDFNLTESDTV 908
Query: 2073 RPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQP-PEGHPGKPEPSRAKSRPLPN 2131
+ P+ E +PL + A + + G A P P PG+ P A S P P
Sbjct: 909 KRRPK--------CREREPLQTALLAFGVASATPGPAAPLPSPTPGESPP--ASSLPQPE 958
Query: 2132 MPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
L T P + PP P P
Sbjct: 959 PSSLPAQGVPTPLAPSPAMQPPVPPCPGP 987
Score = 45.1 bits (105), Expect = 8e-04
Identities = 49/171 (28%), Positives = 64/171 (37%), Gaps = 24/171 (14%)
Query: 1663 TLSELAEGSERPG--------PKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADG 1714
TL A + RPG P V P T S + ++G P P L+
Sbjct: 740 TLGSYATLTRRPGRSALVRTSPSVTPTPARG--TPRSQSFALRARRKGPPPPPPKRLSSV 797
Query: 1715 SGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLE 1774
SGP PEP P+ G +G R+ S AGP+EP SD E
Sbjct: 798 SGPSPEP---------PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTE 848
Query: 1775 RTPPLLPGR-PARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAP 1824
P G P+R E P EE +++ +Q+P P P P P P
Sbjct: 849 EEEPGPEGTPPSRGSSGEGLP---FAEEGNLTIKQRPKPAGP-PPRETPVP 895
Score = 43.5 bits (101), Expect = 0.002
Identities = 55/201 (27%), Positives = 70/201 (34%), Gaps = 44/201 (21%)
Query: 1663 TLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPG---- 1718
TLSE A SE PGP P S E G EG P P SG G
Sbjct: 824 TLSEPAGPSEPPGPPAPAGPA-------SDTEEEEPGPEGTP-----PSRGSSGEGLPFA 871
Query: 1719 ----------PEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATV 1768
P+P G P +D + + +R+ P+ EP+ T A +
Sbjct: 872 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRR----PKCREREPLQT--ALL 925
Query: 1769 CHSDLERTPPLLPGRPARDRGPESRPTELSL---EELSISARQQPTPLTPAQ-------P 1818
TP P P P P SL E S+ A+ PTPL P+ P
Sbjct: 926 AFGVASATPG--PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPP 983
Query: 1819 APAPAPATTTGTRAGGHPEEP 1839
P P ++ +R G E P
Sbjct: 984 CPGPGLESSAASRWNGETEPP 1004
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 58.2 bits (139), Expect = 9e-08
Identities = 112/509 (22%), Positives = 167/509 (32%), Gaps = 86/509 (16%)
Query: 1667 LAEGSER--PGPKVCGLPGARMTTDVSHKASPE----DGQEGLPQPKKPPLADGSGPGPE 1720
L+EG R GP++ + G + A P G E P+ + G P P
Sbjct: 632 LSEGGRRLAKGPELMAIEGLE-NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPL 690
Query: 1721 PGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLL 1780
P + P G + SG +++ +P+ +P E + ER P L
Sbjct: 691 PPAR------SPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGT-ERPPKLC 743
Query: 1781 PGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAP-ATTTGTRAGGHPEEP 1839
P + GP P + S P+ PAP P P A + G P P
Sbjct: 744 SSLPGQ--GPP--PYVFMYPQGS-----------PSSPAPGPPPGAPWAFSYLAGPPATP 788
Query: 1840 LSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEA 1899
KR+ + G T + +G A G V + L ++ A
Sbjct: 789 PDPPRPKRRSHSLSRPGPT---------EGDAEGEAE--GPVGSTLGSYATLTRRPGRSA 837
Query: 1900 ALEQAVKFCQVHLGAAAQRQA-------SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVP 1952
+ + + Q+ G P PK +V +P+P P
Sbjct: 838 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLS---------SVSGPSPEPPP 888
Query: 1953 ADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLG 2012
D P + T PR + S+ PGPP P P + G
Sbjct: 889 LDESPGPKEGATGPRRRTLSEPA-------------GPSEPPGPPAPAGPASDTEEEEPG 935
Query: 2013 PEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKL 2072
PEG +R + G P E + +K P PA P P E + G + ++ +
Sbjct: 936 PEGTPPSRGSSGEGLPFAE-EGNLTIKQRP--KPAGPP--PRETPVPPGLDFNLTESDTV 990
Query: 2073 RPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQP-PEGHPGKPEPSRAKSRPLPN 2131
+ P+ E +PL + A + + G A P P PG+ P A S P P
Sbjct: 991 KRRPK--------CREREPLQTALLAFGVASATPGPAAPLPSPTPGESPP--ASSLPQPE 1040
Query: 2132 MPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
L T P + PP P P
Sbjct: 1041 PSSLPAQGVPTPLAPSPAMQPPVPPCPGP 1069
Score = 45.1 bits (105), Expect = 8e-04
Identities = 49/171 (28%), Positives = 64/171 (37%), Gaps = 24/171 (14%)
Query: 1663 TLSELAEGSERPG--------PKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADG 1714
TL A + RPG P V P T S + ++G P P L+
Sbjct: 822 TLGSYATLTRRPGRSALVRTSPSVTPTPARG--TPRSQSFALRARRKGPPPPPPKRLSSV 879
Query: 1715 SGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLE 1774
SGP PEP P+ G +G R+ S AGP+EP SD E
Sbjct: 880 SGPSPEP---------PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTE 930
Query: 1775 RTPPLLPGR-PARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAP 1824
P G P+R E P EE +++ +Q+P P P P P P
Sbjct: 931 EEEPGPEGTPPSRGSSGEGLP---FAEEGNLTIKQRPKPAGP-PPRETPVP 977
Score = 43.5 bits (101), Expect = 0.002
Identities = 55/201 (27%), Positives = 70/201 (34%), Gaps = 44/201 (21%)
Query: 1663 TLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPG---- 1718
TLSE A SE PGP P S E G EG P P SG G
Sbjct: 906 TLSEPAGPSEPPGPPAPAGPA-------SDTEEEEPGPEGTP-----PSRGSSGEGLPFA 953
Query: 1719 ----------PEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATV 1768
P+P G P +D + + +R+ P+ EP+ T A +
Sbjct: 954 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRR----PKCREREPLQT--ALL 1007
Query: 1769 CHSDLERTPPLLPGRPARDRGPESRPTELSL---EELSISARQQPTPLTPAQ-------P 1818
TP P P P P SL E S+ A+ PTPL P+ P
Sbjct: 1008 AFGVASATPG--PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPP 1065
Query: 1819 APAPAPATTTGTRAGGHPEEP 1839
P P ++ +R G E P
Sbjct: 1066 CPGPGLESSAASRWNGETEPP 1086
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 58.2 bits (139), Expect = 9e-08
Identities = 65/238 (27%), Positives = 96/238 (40%), Gaps = 25/238 (10%)
Query: 1938 FFPVTVVPTAPDPVPADSVQRPSDAHTKPR--PALAAATTIITCPPSASASTLDQSKDPG 1995
F VT+ T D + ++ + PS A P PA A A P ASA+T ++++
Sbjct: 481 FSAVTLQDTVSDRLASEEL--PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEV 538
Query: 1996 PPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAE 2055
PPRP P+ T S E++AR + + P + PQV + +S PA P
Sbjct: 539 PPRPASPKVTRSPPETAAPVEDMARRTKRPA-PARPTMPPPQVSGSRSSPPAPP------ 591
Query: 2056 AALGTGAEPTCSQEGKLRPEPRR-DGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEG 2114
P G + PRR G + A + PL P + + A P
Sbjct: 592 ------LPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPA 645
Query: 2115 HPGKPEPSRAKSRPLPNMPKLVIPSA-ATKFPPEITVTPPTPTLLSPK---GSISEET 2168
PG PS L N ++ + +A A PE PTP + P+ S++ ET
Sbjct: 646 SPGPASPSPVS---LSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLASET 700
Score = 33.9 bits (76), Expect = 1.8
Identities = 26/100 (26%), Positives = 37/100 (37%), Gaps = 8/100 (8%)
Query: 1752 SPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPT 1811
+P P + A + ERT +P RPA + S P + E ++P
Sbjct: 510 TPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPA 569
Query: 1812 PLTPAQPAP--------APAPATTTGTRAGGHPEEPLSRL 1843
P P P P PAP G+ + G P+ RL
Sbjct: 570 PARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRL 609
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 57.8 bits (138), Expect = 1e-07
Identities = 87/415 (20%), Positives = 139/415 (33%), Gaps = 70/415 (16%)
Query: 1803 SISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLD 1862
S+S + PA P +P +G + S S K +T+
Sbjct: 26 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK-------AETVKKS 78
Query: 1863 AYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG 1922
A +V ++ + + + E++ S+T + ++ ++ + G +
Sbjct: 79 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 138
Query: 1923 DTPTTPKHPKD-SRENFFPVTVVPTAPD-PVPADSVQRPSDAHTKPRPALAAATTIITCP 1980
PKD ++N +P+ D +DS + +P PAL A T + P
Sbjct: 139 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAP 197
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
SA PG P+ P TPS ++ P+G A A P P ++
Sbjct: 198 SSAP---------PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 248
Query: 2041 APT---SSPAEPHCWP---------------AEAALGTGAEPTCSQEGKLRPEPRRDGEA 2082
AP P PH P + + + A+P +G P + G
Sbjct: 249 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 308
Query: 2083 QEAASETQPLSSPPTAASSKAP---------------------SSGSAQPPEGHPGKPEP 2121
+ QP PP A+ +AP + S QPP P P P
Sbjct: 309 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368
Query: 2122 ---SRAKSRPLPNMPKLVIPSAATKFPPEIT--------VTPPTPTLLSPKGSIS 2165
K P +P+L P A K PP ++ P P L P S+S
Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/461 (21%), Positives = 143/461 (31%), Gaps = 68/461 (14%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSG----PGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDK 1750
S Q+ + Q + P L +G P P G L P S
Sbjct: 171 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 230
Query: 1751 ESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQP 1810
+ PT P V H+ +++ P L P RP P L+ L+ SA Q
Sbjct: 231 PNQPQAPTAP-------VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPS 283
Query: 1811 TPLTPAQPAPAPAPATTTGTRAGG---HPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVW 1867
P P P +AG HP P + L G+ L +
Sbjct: 284 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP-----QPFGLPPQASQGQAPLGTS---- 334
Query: 1868 QQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG-DTPT 1926
AY ++ S++ + +Q E L A H+ P
Sbjct: 335 ----PAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQ 389
Query: 1927 TPKHPKD-SRENFFPVTV---VPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPS 1982
KHP S + F + P A P+ + S P AH P + + + + P
Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 449
Query: 1983 ASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAP 2042
T Q+ P PP H P +A P A+ P P +P +
Sbjct: 450 PPGLTQSQNLPP-PPASHPPTGLHQVAPQPP-------FAQHPFVPGGPPPITPPTCPST 501
Query: 2043 TSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSK 2102
++ PA P GT A+P CS G A S S P K
Sbjct: 502 STPPAGP---------GTSAQPPCS------------GAAASGGSIAGGSSCPLPTVQIK 540
Query: 2103 APSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATK 2143
+ A+ PE P P P P + PS A++
Sbjct: 541 EEALDDAEEPESPPPPPR------SPSPEPTVVDTPSHASQ 575
Score = 36.6 bits (83), Expect = 0.28
Identities = 51/251 (20%), Positives = 92/251 (36%), Gaps = 33/251 (13%)
Query: 1271 ILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTL 1330
+ K + + D G+ + + + R K P AS + ++ED SS
Sbjct: 1 MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQP-ASPDGRTSPINEDIRSSGRN- 58
Query: 1331 PGPGASLPSSSGPGLTSPPYTATPIDHD----YVKCKKPHQQATPDDRSQDSTAVALSDS 1386
P A+ SS+ + +A + + K+ ++ D D T+ S
Sbjct: 59 -SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS---SKK 114
Query: 1387 SSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQG----------ATEERGKN 1436
+ TQ+ + P S EG +S + + + + + KD+ + ++ +
Sbjct: 115 TKTQEI-SRPNSPSEGEGESSDSRSV---NDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 170
Query: 1437 EESLESTEGFRAAEQGVQKPAAETPA-SACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQ 1495
+S + +A +Q P TPA S+ PG P TP G P PQ
Sbjct: 171 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP--------GPTPSATAVPPQ 222
Query: 1496 GLPAGAEEQRQ 1506
G P ++ Q
Sbjct: 223 GSPTASQAPNQ 233
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.8 bits (138), Expect = 1e-07
Identities = 87/415 (20%), Positives = 139/415 (33%), Gaps = 70/415 (16%)
Query: 1803 SISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLD 1862
S+S + PA P +P +G + S S K +T+
Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK-------AETVKKS 632
Query: 1863 AYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG 1922
A +V ++ + + + E++ S+T + ++ ++ + G +
Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 692
Query: 1923 DTPTTPKHPKD-SRENFFPVTVVPTAPD-PVPADSVQRPSDAHTKPRPALAAATTIITCP 1980
PKD ++N +P+ D +DS + +P PAL A T + P
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAP 751
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
SA PG P+ P TPS ++ P+G A A P P ++
Sbjct: 752 SSAP---------PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 802
Query: 2041 APT---SSPAEPHCWP---------------AEAALGTGAEPTCSQEGKLRPEPRRDGEA 2082
AP P PH P + + + A+P +G P + G
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 862
Query: 2083 QEAASETQPLSSPPTAASSKAP---------------------SSGSAQPPEGHPGKPEP 2121
+ QP PP A+ +AP + S QPP P P P
Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Query: 2122 ---SRAKSRPLPNMPKLVIPSAATKFPPEIT--------VTPPTPTLLSPKGSIS 2165
K P +P+L P A K PP ++ P P L P S+S
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/461 (21%), Positives = 143/461 (31%), Gaps = 68/461 (14%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSG----PGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDK 1750
S Q+ + Q + P L +G P P G L P S
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 784
Query: 1751 ESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQP 1810
+ PT P V H+ +++ P L P RP P L+ L+ SA Q
Sbjct: 785 PNQPQAPTAP-------VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPS 837
Query: 1811 TPLTPAQPAPAPAPATTTGTRAGG---HPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVW 1867
P P P +AG HP P + L G+ L +
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP-----QPFGLPPQASQGQAPLGTS---- 888
Query: 1868 QQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG-DTPT 1926
AY ++ S++ + +Q E L A H+ P
Sbjct: 889 ----PAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQ 943
Query: 1927 TPKHPKD-SRENFFPVTV---VPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPS 1982
KHP S + F + P A P+ + S P AH P + + + + P
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 1983 ASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAP 2042
T Q+ P PP H P +A P A+ P P +P +
Sbjct: 1004 PPGLTQSQNLPP-PPASHPPTGLHQVAPQPP-------FAQHPFVPGGPPPITPPTCPST 1055
Query: 2043 TSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSK 2102
++ PA P GT A+P CS G A S S P K
Sbjct: 1056 STPPAGP---------GTSAQPPCS------------GAAASGGSIAGGSSCPLPTVQIK 1094
Query: 2103 APSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATK 2143
+ A+ PE P P P P + PS A++
Sbjct: 1095 EEALDDAEEPESPPPPPR------SPSPEPTVVDTPSHASQ 1129
Score = 36.6 bits (83), Expect = 0.28
Identities = 51/251 (20%), Positives = 92/251 (36%), Gaps = 33/251 (13%)
Query: 1271 ILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTL 1330
+ K + + D G+ + + + R K P AS + ++ED SS
Sbjct: 555 MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQP-ASPDGRTSPINEDIRSSGRN- 612
Query: 1331 PGPGASLPSSSGPGLTSPPYTATPIDHD----YVKCKKPHQQATPDDRSQDSTAVALSDS 1386
P A+ SS+ + +A + + K+ ++ D D T+ S
Sbjct: 613 -SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS---SKK 668
Query: 1387 SSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQG----------ATEERGKN 1436
+ TQ+ + P S EG +S + + + + + KD+ + ++ +
Sbjct: 669 TKTQEI-SRPNSPSEGEGESSDSRSV---NDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 724
Query: 1437 EESLESTEGFRAAEQGVQKPAAETPA-SACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQ 1495
+S + +A +Q P TPA S+ PG P TP G P PQ
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP--------GPTPSATAVPPQ 776
Query: 1496 GLPAGAEEQRQ 1506
G P ++ Q
Sbjct: 777 GSPTASQAPNQ 787
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.8 bits (138), Expect = 1e-07
Identities = 87/415 (20%), Positives = 139/415 (33%), Gaps = 70/415 (16%)
Query: 1803 SISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLD 1862
S+S + PA P +P +G + S S K +T+
Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK-------AETVKKS 632
Query: 1863 AYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG 1922
A +V ++ + + + E++ S+T + ++ ++ + G +
Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 692
Query: 1923 DTPTTPKHPKD-SRENFFPVTVVPTAPD-PVPADSVQRPSDAHTKPRPALAAATTIITCP 1980
PKD ++N +P+ D +DS + +P PAL A T + P
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAP 751
Query: 1981 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM 2040
SA PG P+ P TPS ++ P+G A A P P ++
Sbjct: 752 SSAP---------PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 802
Query: 2041 APT---SSPAEPHCWP---------------AEAALGTGAEPTCSQEGKLRPEPRRDGEA 2082
AP P PH P + + + A+P +G P + G
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 862
Query: 2083 QEAASETQPLSSPPTAASSKAP---------------------SSGSAQPPEGHPGKPEP 2121
+ QP PP A+ +AP + S QPP P P P
Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Query: 2122 ---SRAKSRPLPNMPKLVIPSAATKFPPEIT--------VTPPTPTLLSPKGSIS 2165
K P +P+L P A K PP ++ P P L P S+S
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/461 (21%), Positives = 143/461 (31%), Gaps = 68/461 (14%)
Query: 1695 SPEDGQEGLPQPKKPPLADGSG----PGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDK 1750
S Q+ + Q + P L +G P P G L P S
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 784
Query: 1751 ESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQP 1810
+ PT P V H+ +++ P L P RP P L+ L+ SA Q
Sbjct: 785 PNQPQAPTAP-------VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPS 837
Query: 1811 TPLTPAQPAPAPAPATTTGTRAGG---HPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVW 1867
P P P +AG HP P + L G+ L +
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP-----QPFGLPPQASQGQAPLGTS---- 888
Query: 1868 QQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASG-DTPT 1926
AY ++ S++ + +Q E L A H+ P
Sbjct: 889 ----PAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTPIPQLPAPQ 943
Query: 1927 TPKHPKD-SRENFFPVTV---VPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPS 1982
KHP S + F + P A P+ + S P AH P + + + + P
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 1983 ASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAP 2042
T Q+ P PP H P +A P A+ P P +P +
Sbjct: 1004 PPGLTQSQNLPP-PPASHPPTGLHQVAPQPP-------FAQHPFVPGGPPPITPPTCPST 1055
Query: 2043 TSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSK 2102
++ PA P GT A+P CS G A S S P K
Sbjct: 1056 STPPAGP---------GTSAQPPCS------------GAAASGGSIAGGSSCPLPTVQIK 1094
Query: 2103 APSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATK 2143
+ A+ PE P P P P + PS A++
Sbjct: 1095 EEALDDAEEPESPPPPPR------SPSPEPTVVDTPSHASQ 1129
Score = 36.6 bits (83), Expect = 0.28
Identities = 51/251 (20%), Positives = 92/251 (36%), Gaps = 33/251 (13%)
Query: 1271 ILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTL 1330
+ K + + D G+ + + + R K P AS + ++ED SS
Sbjct: 555 MFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQP-ASPDGRTSPINEDIRSSGRN- 612
Query: 1331 PGPGASLPSSSGPGLTSPPYTATPIDHD----YVKCKKPHQQATPDDRSQDSTAVALSDS 1386
P A+ SS+ + +A + + K+ ++ D D T+ S
Sbjct: 613 -SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS---SKK 668
Query: 1387 SSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQG----------ATEERGKN 1436
+ TQ+ + P S EG +S + + + + + KD+ + ++ +
Sbjct: 669 TKTQEI-SRPNSPSEGEGESSDSRSV---NDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 724
Query: 1437 EESLESTEGFRAAEQGVQKPAAETPA-SACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQ 1495
+S + +A +Q P TPA S+ PG P TP G P PQ
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP--------GPTPSATAVPPQ 776
Query: 1496 GLPAGAEEQRQ 1506
G P ++ Q
Sbjct: 777 GSPTASQAPNQ 787
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 55.8 bits (133), Expect = 4e-07
Identities = 125/533 (23%), Positives = 175/533 (32%), Gaps = 107/533 (20%)
Query: 1676 PKVCGLPGARMTTD--VSHKASPEDGQEGLP--QPKKPPLADGSGPGPEPGGKVGLLNHR 1731
P GL G R TT + +P+ + L P PP GP P P G+ +H
Sbjct: 470 PFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA 529
Query: 1732 PVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTP--PLLPGRPARDRG 1789
PV+ P+ P + T S P P+ PG
Sbjct: 530 PVS--------------------GSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPA 569
Query: 1790 PESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKL 1849
P S S + +SA PL P+ APAP G PE P +R R
Sbjct: 570 PPSAAAMTSTASIFLSA-----PLRPSARPEAPAPGP-------GAPEPPSAREQR---- 613
Query: 1850 LEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMS---ETYMLIKQVD---------- 1896
+ +T +L R ++G + + G+ E S E L++ +D
Sbjct: 614 -ISVPAARTGILQEAR--RRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAES 670
Query: 1897 --EEAALEQAVKFCQV--HLGAAAQRQASGDTPTT--PKHPKDSRENFFPVTVVPTAPDP 1950
EE AL + C +GA + + TP T P PK + P T P AP P
Sbjct: 671 GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-TPPPMTPKTPPPVAPKP 729
Query: 1951 VPADSVQ-----RPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGP---PRPHRP 2002
+ S A P L + + A PGP PRP P
Sbjct: 730 PSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 789
Query: 2003 EATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHC---WPAEAALG 2059
TP SL P + + R P + P SP P P + G
Sbjct: 790 SPTP---SLPPSWKYSPNI-----------RAPPPIAYNPLLSPFFPQAARTLPKAQSQG 835
Query: 2060 TGAEPTCSQEGK--LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPG 2117
A P + +R +P + A E P P + S K +A+ E
Sbjct: 836 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPK-----TARVQEIRRF 890
Query: 2118 KPEPSRAKSRPLPNMPKLVIPSAATKFPPEI--------TVTPPTPTLLSPKG 2162
+ + PL P ++ P AAT I V P P +P+G
Sbjct: 891 STPAPQPTAEPL--APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRG 941
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 55.8 bits (133), Expect = 4e-07
Identities = 125/533 (23%), Positives = 175/533 (32%), Gaps = 107/533 (20%)
Query: 1676 PKVCGLPGARMTTD--VSHKASPEDGQEGLP--QPKKPPLADGSGPGPEPGGKVGLLNHR 1731
P GL G R TT + +P+ + L P PP GP P P G+ +H
Sbjct: 246 PFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA 305
Query: 1732 PVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTP--PLLPGRPARDRG 1789
PV+ P+ P + T S P P+ PG
Sbjct: 306 PVS--------------------GSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPA 345
Query: 1790 PESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKL 1849
P S S + +SA PL P+ APAP G PE P +R R
Sbjct: 346 PPSAAAMTSTASIFLSA-----PLRPSARPEAPAPGP-------GAPEPPSAREQR---- 389
Query: 1850 LEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMS---ETYMLIKQVD---------- 1896
+ +T +L R ++G + + G+ E S E L++ +D
Sbjct: 390 -ISVPAARTGILQEAR--RRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAES 446
Query: 1897 --EEAALEQAVKFCQV--HLGAAAQRQASGDTPTT--PKHPKDSRENFFPVTVVPTAPDP 1950
EE AL + C +GA + + TP T P PK + P T P AP P
Sbjct: 447 GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-TPPPMTPKTPPPVAPKP 505
Query: 1951 VPADSVQ-----RPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGP---PRPHRP 2002
+ S A P L + + A PGP PRP P
Sbjct: 506 PSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 565
Query: 2003 EATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHC---WPAEAALG 2059
TP SL P + + R P + P SP P P + G
Sbjct: 566 SPTP---SLPPSWKYSPNI-----------RAPPPIAYNPLLSPFFPQAARTLPKAQSQG 611
Query: 2060 TGAEPTCSQEGK--LRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPG 2117
A P + +R +P + A E P P + S K +A+ E
Sbjct: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPK-----TARVQEIRRF 666
Query: 2118 KPEPSRAKSRPLPNMPKLVIPSAATKFPPEI--------TVTPPTPTLLSPKG 2162
+ + PL P ++ P AAT I V P P +P+G
Sbjct: 667 STPAPQPTAEPL--APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRG 717
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 55.5 bits (132), Expect = 6e-07
Identities = 108/463 (23%), Positives = 156/463 (33%), Gaps = 72/463 (15%)
Query: 1699 GQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPT 1758
G EG P+P PPL G P + + +D +P PT
Sbjct: 507 GTEGPPRPAPPPLPHREGFLGPPASRFSV------------------GTQDSHTPPTPPT 548
Query: 1759 EPMDTSEATV-CHSDLERTPPLLPGRP--ARDRGPESRPTELSLEELSISARQQPTPLTP 1815
+S + HS P P P AR P RP S + Q PL P
Sbjct: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP-------SPAQNPQDPPLVP 601
Query: 1816 AQPAPAPAPATTTGTRAGG---HPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQK 1872
A PAP ++ G PE P R+S + L A Q
Sbjct: 602 LTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP---QPVPP 658
Query: 1873 GVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPK 1932
GV R R+ E E+ +F + G A + ++ K
Sbjct: 659 GVGELPARGPRLFD-----FPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIR-----K 708
Query: 1933 DSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKP-RPALAAATTIITCPPSASASTLDQS 1991
+ + V P P P S+Q P T P A A A T T + + +T ++
Sbjct: 709 EEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEE 768
Query: 1992 KDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHC 2051
K P P P P +A P + PP P + +K + + +C
Sbjct: 769 KKPPPALP----PPPPLAKFPPPSQPQPP-------PPPPPSPASLLKSLASVLEGQKYC 817
Query: 2052 WPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQ- 2110
+ GTGA ++ G L P + A+ P S+ P+A S PS+ S+
Sbjct: 818 Y-----RGTGA-AVSTRPGPL-PTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ 870
Query: 2111 -PPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTP 2152
G P E RA P+P P T+ PP +++ P
Sbjct: 871 FSTSGGPWARE-RRAGEEPVPG------PMTPTQPPPPLSLPP 906
Score = 43.1 bits (100), Expect = 0.003
Identities = 122/513 (23%), Positives = 159/513 (30%), Gaps = 101/513 (19%)
Query: 1706 PKKPPLADGSGPGPEPGGKVG---LLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMD 1762
P PP GPGP P G L RP D +S Q SP A
Sbjct: 331 PAAPP-----GPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAA------- 378
Query: 1763 TSEATVCHSDLERTPPLLPGRPARD----------RGPESRPT-------ELSLEELSIS 1805
T C PP LPG RG E P + E+S
Sbjct: 379 ---TTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHH 435
Query: 1806 ARQQPTPLTPAQP---APAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLD 1862
R P+ + +P APA P + P P RL R
Sbjct: 436 GRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRP---------------P 480
Query: 1863 AYRVWQQGQKGVAYDLGRVE-RIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQAS 1921
W KG A R + I+ E + + A + + LG A R +
Sbjct: 481 PPPAWL---KGPACRAAREDGEILEELFFGTEGPPRPAP--PPLPHREGFLGPPASRFSV 535
Query: 1922 GD----TPTTPKHPKDSRENF-------FPVTVVPTAPDPVPADSV----QRPSDAHTKP 1966
G TP TP P S N P V P P A S+ + PS A
Sbjct: 536 GTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQ 595
Query: 1967 RPALAAATTIITCPPSASA--STLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEG 2024
P L T + P +S +T + P PRP GP L++ +
Sbjct: 596 DPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQP 655
Query: 2025 TSFPP---QEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGE 2081
PP + P P++ P + + PAE + + K+ E R E
Sbjct: 656 V--PPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI---LPDGLANIMKMLDESIRKEE 710
Query: 2082 AQ---EAASETQP--------LSSP---PTAASSKAPSSGSAQPPEGHPGKPEPSRAKSR 2127
Q EA QP L SP TA ++ AP+ + +
Sbjct: 711 EQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKK 770
Query: 2128 PLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
P P +P P KFPP PP P SP
Sbjct: 771 PPPALPP---PPPLAKFPPPSQPQPPPPPPPSP 800
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 55.5 bits (132), Expect = 6e-07
Identities = 145/669 (21%), Positives = 207/669 (30%), Gaps = 171/669 (25%)
Query: 1613 LAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELA---- 1668
LA + D S + SS L + + K ++ +++ R L+ + ++LS+L
Sbjct: 203 LAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRR--LSSRAQSESLSDLTCTPE 260
Query: 1669 --EGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP---------------- 1710
E E+P +V P R ++ A + G P P PP
Sbjct: 261 EEENEEKPLLEVS--PEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
Query: 1711 ---LADGSGPGPEPGGKVG------------LLNHRPVAMDAGDSADQSGERKDKESPRA 1755
+ +G PG +P + L P + + G ++D E+P A
Sbjct: 319 TASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPA 378
Query: 1756 GPTEPM-DTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLT 1814
GP P D +E VC + + P P D P T+ + + SAR P
Sbjct: 379 GPCAPATDKAEEVVCAPE-DVASPFPTAIPEGDTTPPE--TDPAATSEAPSARDGPERSV 435
Query: 1815 PAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGV 1874
P + P P G EP +R+ + E G
Sbjct: 436 PKEAEPTPPVLPDEEKGPPGPAPEP------EREAETEPERGAGT--------------- 474
Query: 1875 AYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDS 1934
ERI +E A A K C H AAA + P
Sbjct: 475 -----EPERIGTEPSTA------PAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPV 523
Query: 1935 RENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAAT--TIITCPPSASASTLDQSK 1992
+ AP+ A+ + P + P A + S S+
Sbjct: 524 EPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP 583
Query: 1993 DPGPPRP-HRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHS-----------PQVKM 2040
PG RP R +A GP A + + P EP+H+ PQ
Sbjct: 584 RPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLP--EPQHAKPGPRKLAERGPQDSG 641
Query: 2041 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRP-EPR----------------RDGEAQ 2083
+SPA P P EAA G C + P E R RDG +Q
Sbjct: 642 DRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQ 701
Query: 2084 EA--------------------ASETQPLSSPPTAASSKAPS---SGSAQPPEGHPGKP- 2119
E E PL + P ++APS G A+PPE KP
Sbjct: 702 EVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPP 761
Query: 2120 ------------------------------EPSRAKSRPLPNMPKLVIPSAAT------- 2142
EP A+ RPL + +P AAT
Sbjct: 762 LPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQ 821
Query: 2143 KFPPEITVT 2151
PP ITVT
Sbjct: 822 PAPPWITVT 830
Score = 50.1 bits (118), Expect = 2e-05
Identities = 113/456 (24%), Positives = 144/456 (31%), Gaps = 83/456 (18%)
Query: 1784 PARDRGPESRPTELSLEELSISARQQPTP---LTPAQPAPAPAP--------------AT 1826
P + E E+S EE S +Q P P PAP P P A
Sbjct: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
Query: 1827 TTGTRAGGHP-EEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIM 1885
T GG P E+P SR + L + ES TL ++ +G D G+ +
Sbjct: 319 TASVEEGGVPGEDPSSRPATPE--LAEPESAPTLRVEPPSP-PEGPPNPGPDGGKQDGEA 375
Query: 1886 SETYMLIKQVDEE----AALEQAVKFCQVHLGAAAQRQASGDTPTTPKHP--KDSRENFF 1939
D+ A E + D T + P +D E
Sbjct: 376 PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
Query: 1940 PVTVVPTAP--------DPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQS 1991
P PT P P PA +R +A T+P I PS + +
Sbjct: 436 PKEAEPTPPVLPDEEKGPPGPAPEPER--EAETEPERGAGTEPERIGTEPSTAPA----- 488
Query: 1992 KDPGPPRP-----HRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSP 2046
P PP P HRP A AS GP AE PP EP P A ++P
Sbjct: 489 --PSPPAPKSCLKHRPAA----ASEGPAASPPLAAAES---PPVEP--GPGSLDAEAAAP 537
Query: 2047 AEPHCWPAEA------------------ALGTGAEPTCSQEGKLRPEPRRDGEAQEAASE 2088
P AEA A GA+ + RP P E AS
Sbjct: 538 ERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVS-RPLERASG 596
Query: 2089 TQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSR-PLPNMPKLVIPSAATKFPPE 2147
PL+ S+A PE KP P + R P + + P+ K P E
Sbjct: 597 RLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQE 656
Query: 2148 ITVTP----PTPTLLSPKGSISEET-KQKLKSAILS 2178
P P P P S KL+S LS
Sbjct: 657 AAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLS 692
Score = 46.6 bits (109), Expect = 3e-04
Identities = 70/286 (24%), Positives = 98/286 (34%), Gaps = 44/286 (15%)
Query: 1912 LGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVP---TAPDPVPADSVQRPSDAHTKPRP 1968
L + AQ ++ D TP+ ++ + V+ + V D P P P
Sbjct: 243 LSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPP 302
Query: 1969 ALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFP 2028
A A SA +++++ PG RP ATP +A PE RV E S P
Sbjct: 303 GGARARRARLQHSSALTASVEEGGVPGEDPSSRP-ATPELAE--PESAPTLRV-EPPSPP 358
Query: 2029 PQEPRHSP----QVKMAPTSSPAEPHCWPAEAALGTGAE-----PTCSQEGKLRPEPR-- 2077
P P Q AP + P P AE + + PT EG P
Sbjct: 359 EGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDP 418
Query: 2078 ---------RDGEAQEAASETQPL--------SSPPTAA------SSKAPSSGSAQPPEG 2114
RDG + E +P PP A + P G+ PE
Sbjct: 419 AATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPER 478
Query: 2115 HPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2160
+P + A S P P P+AA++ P +PP SP
Sbjct: 479 IGTEPSTAPAPSPPAPKSCLKHRPAAASEGP---AASPPLAAAESP 521
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 54.7 bits (130), Expect = 1e-06
Identities = 66/302 (21%), Positives = 104/302 (34%), Gaps = 47/302 (15%)
Query: 1920 ASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITC 1979
A+G P+ P R PV V PT P P P P +A +T
Sbjct: 300 ATGLIENRPQSPATGRT---PVFVSPTPPPP---------------PPPLPSALST---- 337
Query: 1980 PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S+ +++ + P P P P AT A P ++A G P P P V+
Sbjct: 338 --SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P + A P C + + P P+ + + PL P
Sbjct: 396 PSPPVARAAPVC----------------ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPL--PNMPKLVIPSAATKFPPEITVTPPTPTL 2157
SS + A PP G P + PL P+ P VIP++ K P P +
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS-----TLPVI 494
Query: 2158 LSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDY 2217
+ + E ++ ++ + Q + E + +L +SE D + D
Sbjct: 495 SDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDE 554
Query: 2218 MD 2219
+D
Sbjct: 555 VD 556
Score = 36.6 bits (83), Expect = 0.28
Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 1962 AHTKPRPA-----LAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGE 2016
+H + RP + + ++ P S + L ++++ RPH P P M G
Sbjct: 233 SHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKP 292
Query: 2017 ELARVAEGTSFPPQEPRHSPQ-----VKMAPTSSPAEPHCWPAEAALGTG---AEPTCSQ 2068
++ T P+ SP V ++PT P P P +AL T A T +
Sbjct: 293 IPTCISSATGLIENRPQ-SPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTP 348
Query: 2069 EGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2128
+ P P PP A + +AP A PP P + P P
Sbjct: 349 PPPVPPPP------------------PPPATALQAP----AVPPPPAPLQIAPGVLHPAP 386
Query: 2129 LPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSI 2164
P P LV PS + T P L P+G +
Sbjct: 387 PPIAPPLVQPSPPVARAAPVCETVPVHPL--PQGEV 420
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 54.7 bits (130), Expect = 1e-06
Identities = 66/302 (21%), Positives = 104/302 (34%), Gaps = 47/302 (15%)
Query: 1920 ASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITC 1979
A+G P+ P R PV V PT P P P P +A +T
Sbjct: 300 ATGLIENRPQSPATGRT---PVFVSPTPPPP---------------PPPLPSALST---- 337
Query: 1980 PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S+ +++ + P P P P AT A P ++A G P P P V+
Sbjct: 338 --SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P + A P C + + P P+ + + PL P
Sbjct: 396 PSPPVARAAPVC----------------ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPL--PNMPKLVIPSAATKFPPEITVTPPTPTL 2157
SS + A PP G P + PL P+ P VIP++ K P P +
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS-----TLPVI 494
Query: 2158 LSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDY 2217
+ + E ++ ++ + Q + E + +L +SE D + D
Sbjct: 495 SDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDE 554
Query: 2218 MD 2219
+D
Sbjct: 555 VD 556
Score = 36.6 bits (83), Expect = 0.28
Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 1962 AHTKPRPA-----LAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGE 2016
+H + RP + + ++ P S + L ++++ RPH P P M G
Sbjct: 233 SHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKP 292
Query: 2017 ELARVAEGTSFPPQEPRHSPQ-----VKMAPTSSPAEPHCWPAEAALGTG---AEPTCSQ 2068
++ T P+ SP V ++PT P P P +AL T A T +
Sbjct: 293 IPTCISSATGLIENRPQ-SPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTP 348
Query: 2069 EGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2128
+ P P PP A + +AP A PP P + P P
Sbjct: 349 PPPVPPPP------------------PPPATALQAP----AVPPPPAPLQIAPGVLHPAP 386
Query: 2129 LPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSI 2164
P P LV PS + T P L P+G +
Sbjct: 387 PPIAPPLVQPSPPVARAAPVCETVPVHPL--PQGEV 420
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 54.7 bits (130), Expect = 1e-06
Identities = 66/302 (21%), Positives = 104/302 (34%), Gaps = 47/302 (15%)
Query: 1920 ASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITC 1979
A+G P+ P R PV V PT P P P P +A +T
Sbjct: 300 ATGLIENRPQSPATGRT---PVFVSPTPPPP---------------PPPLPSALST---- 337
Query: 1980 PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S+ +++ + P P P P AT A P ++A G P P P V+
Sbjct: 338 --SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P + A P C + + P P+ + + PL P
Sbjct: 396 PSPPVARAAPVC----------------ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPL--PNMPKLVIPSAATKFPPEITVTPPTPTL 2157
SS + A PP G P + PL P+ P VIP++ K P P +
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS-----TLPVI 494
Query: 2158 LSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDY 2217
+ + E ++ ++ + Q + E + +L +SE D + D
Sbjct: 495 SDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDE 554
Query: 2218 MD 2219
+D
Sbjct: 555 VD 556
Score = 36.6 bits (83), Expect = 0.28
Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 1962 AHTKPRPA-----LAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGE 2016
+H + RP + + ++ P S + L ++++ RPH P P M G
Sbjct: 233 SHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKP 292
Query: 2017 ELARVAEGTSFPPQEPRHSPQ-----VKMAPTSSPAEPHCWPAEAALGTG---AEPTCSQ 2068
++ T P+ SP V ++PT P P P +AL T A T +
Sbjct: 293 IPTCISSATGLIENRPQ-SPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTP 348
Query: 2069 EGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2128
+ P P PP A + +AP A PP P + P P
Sbjct: 349 PPPVPPPP------------------PPPATALQAP----AVPPPPAPLQIAPGVLHPAP 386
Query: 2129 LPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSI 2164
P P LV PS + T P L P+G +
Sbjct: 387 PPIAPPLVQPSPPVARAAPVCETVPVHPL--PQGEV 420
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 54.7 bits (130), Expect = 1e-06
Identities = 66/302 (21%), Positives = 104/302 (34%), Gaps = 47/302 (15%)
Query: 1920 ASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITC 1979
A+G P+ P R PV V PT P P P P +A +T
Sbjct: 300 ATGLIENRPQSPATGRT---PVFVSPTPPPP---------------PPPLPSALST---- 337
Query: 1980 PPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVK 2039
S+ +++ + P P P P AT A P ++A G P P P V+
Sbjct: 338 --SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
Query: 2040 MAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAA 2099
+P + A P C + + P P+ + + PL P
Sbjct: 396 PSPPVARAAPVC----------------ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
Query: 2100 SSKAPSSGSAQPPEGHPGKPEPSRAKSRPL--PNMPKLVIPSAATKFPPEITVTPPTPTL 2157
SS + A PP G P + PL P+ P VIP++ K P P +
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS-----TLPVI 494
Query: 2158 LSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDY 2217
+ + E ++ ++ + Q + E + +L +SE D + D
Sbjct: 495 SDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDE 554
Query: 2218 MD 2219
+D
Sbjct: 555 VD 556
Score = 36.6 bits (83), Expect = 0.28
Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 1962 AHTKPRPA-----LAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGE 2016
+H + RP + + ++ P S + L ++++ RPH P P M G
Sbjct: 233 SHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKP 292
Query: 2017 ELARVAEGTSFPPQEPRHSPQ-----VKMAPTSSPAEPHCWPAEAALGTG---AEPTCSQ 2068
++ T P+ SP V ++PT P P P +AL T A T +
Sbjct: 293 IPTCISSATGLIENRPQ-SPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTP 348
Query: 2069 EGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2128
+ P P PP A + +AP A PP P + P P
Sbjct: 349 PPPVPPPP------------------PPPATALQAP----AVPPPPAPLQIAPGVLHPAP 386
Query: 2129 LPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSI 2164
P P LV PS + T P L P+G +
Sbjct: 387 PPIAPPLVQPSPPVARAAPVCETVPVHPL--PQGEV 420
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 54.3 bits (129), Expect = 1e-06
Identities = 68/281 (24%), Positives = 105/281 (37%), Gaps = 43/281 (15%)
Query: 1942 TVVPTAPDPVPADS-VQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPH 2000
TVVP P+P P S + S T P +SA L+Q PG P
Sbjct: 534 TVVPAGPEPPPQSSRAESSSGGGTVP----------------SSAGILEQGPSPGDGSPP 577
Query: 2001 RPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGT 2060
+P+ P A++ G +++A G + PQ S Q+ M + A P A+
Sbjct: 578 KPK-DPVSAAVPAPGRNNSQIASGQN-QPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKK 635
Query: 2061 GAEPTCSQEGKLRPEPRRDGEAQEAASETQP--LSSPPTAASSKAPSSGSAQPPEGHPGK 2118
A P + G P P G + + P LS P S P+ + QPP G P
Sbjct: 636 PA-PAPPKPGN--PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPP-GQPSA 691
Query: 2119 P-------------EPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSIS 2165
P P +A + P P P P TK + PP P L + +
Sbjct: 692 PSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTK---PNSQGPPNPMALPSEHGLE 748
Query: 2166 EETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESS 2206
+ + ++ + S + K++ PA + L + E++
Sbjct: 749 QPSHTPPQTP--TPPSTPPLGKQNPSLPAPQTLAGGNPETA 787
Score = 38.1 bits (87), Expect = 0.097
Identities = 50/198 (25%), Positives = 72/198 (36%), Gaps = 32/198 (16%)
Query: 1665 SELAEGSERPGPKVCGLPGARMTTDVSHKA---SPEDGQEGLPQPKKPPLADGSGPGPEP 1721
S++A G +P +++ H A SP + + +P P G+ P P
Sbjct: 595 SQIASGQNQPQ---AAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHP 651
Query: 1722 GGKV--GLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLE----- 1774
GG+ G H P + S + P P+ P S S L
Sbjct: 652 GGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAP 711
Query: 1775 ---------RTPPLLPGRPARDRGPE--SRPTELSLEELSISARQQPT-PLTP---AQPA 1819
+ PL+ +P P + P+E LE+ S + Q PT P TP Q
Sbjct: 712 NHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP 771
Query: 1820 PAPAPATTTGTRAGGHPE 1837
PAP T AGG+PE
Sbjct: 772 SLPAPQTL----AGGNPE 785
Score = 36.2 bits (82), Expect = 0.37
Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 20/195 (10%)
Query: 2000 HRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSS-----PAEPHCWPA 2054
HR T + + P + +G++ P P PQ A +SS P+
Sbjct: 508 HRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQ 567
Query: 2055 EAALGTGAEPTCSQE-GKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSG---SAQ 2110
+ G G+ P P P R+ +Q A+ + Q P AA S S G +A
Sbjct: 568 GPSPGDGSPPKPKDPVSAAVPAPGRN-NSQIASGQNQ----PQAAAGSHQLSMGQPHNAA 622
Query: 2111 PPEGHP-----GKPEPSRAK-SRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSI 2164
P H KP P+ K P P P S ++ PP ++ PPT + P
Sbjct: 623 GPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHT 682
Query: 2165 SEETKQKLKSAILSA 2179
+ Q + LSA
Sbjct: 683 GQPPGQPSAPSQLSA 697
Score = 32.7 bits (73), Expect = 4.1
Identities = 41/154 (26%), Positives = 57/154 (37%), Gaps = 23/154 (14%)
Query: 1696 PEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRA 1755
P G P+PK P A PG ++ ++P A AG G+ + P
Sbjct: 569 PSPGDGSPPKPKDPVSAAVPAPGRN-NSQIASGQNQPQAA-AGSHQLSMGQPHNAAGP-- 624
Query: 1756 GPTEPMDTSEATVCHSDLERTP-PLLPGRPARDRGPESRPTELSLEELSISARQQPTPLT 1814
S T+ + + P P PG P P P S S Q P L+
Sbjct: 625 --------SPHTLRRAVKKPAPAPPKPGNP-----PPGHPGGQS----SSGTSQHPPSLS 667
Query: 1815 PAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRK 1848
P P +P+P T + G P P S+LS R+
Sbjct: 668 PKPPTRSPSPPTQHTGQPPGQPSAP-SQLSAPRR 700
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,065,426
Number of Sequences: 37866
Number of extensions: 5249686
Number of successful extensions: 32171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 1359
Number of HSP's that attempted gapping in prelim test: 22547
Number of HSP's gapped (non-prelim): 9113
length of query: 2220
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2102
effective length of database: 13,779,330
effective search space: 28964151660
effective search space used: 28964151660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.